[[quoteright:350:[[Disney/{{Zootopia}} http://static.tvtropes.org/pmwiki/pub/images/nick_tranqd.jpg]]]]
[[caption-width-right:350:An '''elephant''' tranquillizer used on a fox?\\
That'll keep him down for awhile.\\
''[-...maybe permanently.-]'']]

If a character needs some InstantSedation, one of the most common delivery methods is the Tranquillizer Dart. Simply put, this is a thin, pointed projectile that is shot, thrown, blown, or otherwise flung at the victim from a distance. The sedative is either smeared on the dart or contained in an ampoule or capsule attached to the dart.

This small projectile, usually fired into the neck or buttocks, seems to put the target to sleep with only enough time to pluck out the dart and stare at it in amazement before passing out. If that much.

Like other forms of InstantSedation, tranquillizer darts are subject to ArtisticLicenseMedicine: [[OneDoseFitsAll the same dose will work on everyone]], they work exactly as fast as the plot demands, are exactly as effective as the plot demands, the effects last exactly as long as the plot demands, and they generally have little or no after-effects beyond a slight headache or some residual grogginess.

Occasionally the dart will have a non-sedative but related effect, delivering a paralytic or amnesiac drug instead, so the victim is still conscious but either can't move or won't remember what happened.

Subtrope of InstantSedation. Sister trope to KnockOutGas which works better for area attacks. Often used in a KnockoutAmbush. Compare StunGun. Sometimes used as FamilyFriendlyFirearms.


[[folder:Anime & Manga]]
* ''Anime/AgentAika'': Aika has a pistol that fires darts. It is used heavily in episode six. In Aika R16 and Aika Zero, guns appear to fire bullets, but they have the same effect as darts.
* ''Webcomic/TowerOfGod'': Koon "recruits" Edin with one of those.
* ''Manga/DetectiveConan'': Conan's wrist-watch tranquilizer needle gun. The victim barely has time to mumble a few words before keeling over. So far, there have been very few characters who have proven resistant to it. When it happens, it catches Conan completely off-guard. Gin shot himself in the arm to overcome the sedation with a rush of pain and adrenaline.
** Subverted in ''Anime/LupinIIIVsDetectiveConan''. Conan uses his watch-dart on Inspector Zenigata, who is so tough that it wears off in no time (though he still goes down quickly). Conan is pretty surprised when it wears off. Tots-san probably built up an immunity to it.
* ''Franchise/LupinIII'': A fairly often trope used when one of the main five characters are shot for real. Zenigata, as the "antagonist" to Lupin, is the frequent target. Usually wears off after his funeral.
* Subverted in ''Anime/MichikoToHatchin''. Michiko appears to be very resilient when hit by a dart from a tranquilizer gun. Twice.
* Subverted in ''New Manga/GetterRobo'', though the writers were probably more concerned with the RuleOfCool than realism. Ryoma gets hit by an animal tranquiliser in the first episode, but it doesn't stop him from running across the street and dropkicking his two attackers before going down. Note that this is ''after'' he had just fought a 3-on-1 fight against some Yakuza goons and had gotten a knife buried into his shoulder.
* In ''Manga/DragonHalf'', Rosario shoots Mink with a knockout dart and she instantly falls. Then Rosario puts two more darts into her right away, [[spoiler:setting up a gag where he and the king think Mink died from the overdose]]. Strangely, at first Rosario accidentally inhaled and got the dart stuck in his tongue, but nothing ever came of this.

[[folder:Comic Books]]
* ComicBook/{{Kaliman}} uses curare-tipped darts (from a blowgun) to paralyze his foes (since he never kills). Ironically, in real life, most curare poisons (there are several under the same appellation) cause death by asphyxia.
* ''Franchise/{{Batman}}''
** Before they learned about each others' secret identity, Bruce Wayne tried to pull this on [[Franchise/{{Superman}} Clark Kent]] so he could change into his cape and cowl. [[CoverBlowingSuperpower This was when Bruce finally realized Clark was Superman.]]
** Batman also used an incredibly amount of darts in ''ComicBook/BatmanTheCult''. In fact, he loaded turrets and rifles with them, basically using them in pretty much the same way everyone else would use bullets. It sure is lucky that nobody can die from the wrong dosage of sedatives, eh?

[[folder:Films -- Animation]]
* In ''WesternAnimation/{{Madagascar}}'', Alex, Marty, Melman, and Gloria are all hit by tranquilizer darts when they are all caught by the animal control while inside New York City's Grand Central Station just right before being locked up into crates and loaded onto a cargo ship that will eventually be hijacked by penguins, causing them to fall out and wash up on the title island.
** When Alex gets darted, the [[http://www.youtube.com/watch?v=jdg-UoAgZio resulting scene]] is [[DisneyAcidSequence very]] [[MushroomSamba interesting]] [[BigLippedAlligatorMoment indeed]].
* On ''WesternAnimation/OpenSeason'', Boog's caretaker has to shoot him with a tranquilizer dart when he apparently goes on a rampage (he's actually fighting with Elliot, who gets several darts to the butt as well).

[[folder:Films -- Live-Action]]
* A {{Lampshaded}} subversion in ''Film/TheGodsMustBeCrazy'' explicitly explains that tranquilizer darts don't take effect immediately. That's why they are rigged to be so easily removed that the victim doesn't know they've been tranked (they feel only the sting, which can be attributed to insects).
* In the opening scene of ''Film/TheRock'', the mercenaries use tranq darts on the soldiers guarding the chemical weapons depot. All of them fall unconscious immediately.
* ''Film/TheAvengers1998''. Sir August renders Mrs. Peel unconscious with a drug-tipped dart.
* ''Film/{{Goldfinger}}''. While Bond is helplessly strapped to a table, Kisch renders him unconscious with a tranquilizer dart pistol.
* ''Film/NeverSayNeverAgain''. James uses a sleep-poisoned blowgun dart on a {{Mook}} guard during UnwinnableTrainingSimulation opening.
* ''Film/SpiesLikeUs''. Emmett Fitz-Hume and Austin Millbarge knock out five Soviet soldiers instantly with "high-compression tranquilizer pistols".
* In the short film made of ''Battleground'' by Creator/StephenKing, TheUnnamed hitman shoots two security guards using a tranquilizer gun. While one goes down immediately, the second guard (a strong, fit-looking man) just yelps from the dart and reaches for his own gun, but the hitman is prepared for this and quickly knocks him out physically.
* Discussed in ''Film/KangarooJack'' when the protagonists accidentally shoot a dart to their airplane pilot while they are airborne; the pilot experiences the effects in stages as noted by one of them.
* Frank Drebin's cufflink tranquilizer darts in the first ''Film/TheNakedGun'' movie. However, they're not ''quite'' instant enough, since the bad guy staggers around long enough to fall over a railing to a CruelAndUnusualDeath.
* ''Film/{{Serenity}}'' subverts this in the [[FinalBattle climactic battle]] when [[WrenchWench Kaylee]] is tranquilised by Reavers. She takes three darts to the neck. Although she quickly begins to feel shaky, she can still hurry (albeit with [[TheMedic Simon's]] help) into the corridor behind and continues to stand, shielded from Reavers by Simon while Zoe and [[BoisterousBruiser Jayne]] struggle to close the blast doors. Only when Simon helps lie her down does she comment she's beginning to lose feeling. Even then, the FinalBattle between [[TheCaptain Mal]] and [[AffablyEvil the Operative]] has to take place and Mal return for us to spot that Kaylee, while not moving very much at all, is still conscious.
* In the 1967 comedy ''Film/ThoroughlyModernMillie'' the darts work instantly, though the earlier KnockoutGas was not played as straight.
* ''Film/RiseOfThePlanetOfTheApes'' has Landon use one of these on Rocket, when he's fighting with Caesar.
* ''Film/SurLaPisteDuMarsupilami''
** The trope is {{exaggerated|Trope}} with Dan Geraldo, who gets ''dozens'' of blowpipe darts in the face before fainting.
-->'''Dan:''' [[NonSequiturThud It stings a bit]].
** Later played straight with tranq darts fired by a rifle, which take out the Marsupilami (as well as a soldier by accident).
* ''Genesis II''. Members of PAX have small pistols that fire tranquilizer darts. They can render the target unconscious in seconds.
* In ''Film/CubeZero'', the soldiers shoot tranq darts at the escaping prisoners, as their mission is retrieval, not elimination.
* In the sequel to ''Film/AceVentura'', Ace takes three darts, which he says "is too much." [[UpToEleven And then he takes four more.]]

* ''Literature/LoneWolf''
** The drugged darts used by Maouk in ''Shadow on the Sand''.
** In the same book, Lone Wolf can use a blowpipe and tranquillizer dart on a guard; [[InstantSedation the effects are instantaneous]].

* A staple of covert operations in Creator/AlanDeanFoster's ''Literature/HumanxCommonwealth'' universe, Instant Sedation darts are most prominently used in ''Bloodhype'', when Kitten Kai-Sung, Mal Hammurabi, and Porsupah are infiltrating the [=AAnn=] enclave on Repler. Possibly justified by being in TheFuture, but it also fails NoBiochemicalBarriers. Oh, well.
* Subverted in the novel ''Franchise/JurassicPark'', where the big ''TyrannosaurusRex'' (yes, there are [[FromBadToWorse two Tyrannosaurs]]) takes over an hour to feel it when she's shot with several times the so-called recommended tranq dose. In fact, she nearly eats the kids while everyone's waiting for her to pitch over.
* In the universe of StevenPerry's ''{{Matador|Series}}'' series, one of the legal loads for the hand-mounted spetsdod is a round loaded with a tranquilizer, appropriately called "Trank".
* ''Literature/{{Dune}}'' has this come up when Leto finds the Shadout Mapes dying on the floor in the palace and [[spoiler:Doctor Yueh]] shoots him with a dart (at the start of the Harkonnens' raid on Arrakis). [[spoiler:Yueh is the family physician, so he knows the duke's body mass, metabolism, and so on.]] Some reference to the drugging of Jessica and Paul is also made; the Baron stands over Jessica as she comes to and tells her, "The drug was timed." This admission tells her the traitor has detailed and intimate knowledge of her vital statistics.
* In Alistair [=MacLean=]'s ''The Golden Gate'', Agent Revson has a device that fires sleep darts that don't have any side effects, which causes their victims to think they fell asleep naturally.
* In the ''Literature/ParadoxTrilogy'', Devi is shot with tranquilizer darts in ''Heaven's Queen''. Because of her resistance to sedatives, the first dart has little effect, and it takes four to bring her down.
* Staple in ''Literature/ButlerParker'', Parker himself usually delivered them through his blowdgun-umbrelly, though he also had ballpoint pens capable of shooting them and in early issues also used a real blowgun. Also, he had similar darts (pins) hidden in the seats of his retooled taxi (to be deployed at the press of a button) and in different forms as needles both in his arsenal and that of his associates.

[[folder:Live-Action TV]]
* Used in ''Series/{{Smallville}}'' on basically everyone who isn't [[NighInvulnerable Clark Kent]], probably more than once.
* ''Series/{{Lost}}''
** Subverted in an episode where Sayid is shot twice with tranquilizing darts. He pulls one dart out and we're led to believe that the trope is playing straight until he surprises the shooter, who approached him to confirm unconsciousness.
** Pretty much played straight in a lot of other episodes, featuring darts, gas and chloroform. Namely, some episodes in this respective order are: "Live Together, Die Alone", "Left Behind" and "Something Nice Back Home".
* ''Series/StargateSG1''
** Tranq guns are used in "Hathor" by O'Neill and Carter to neutralize male soldiers enthralled by Hathor without killing them. As usual, sleep is instantaneous.
** In "In The Line of Duty", when Sam/Jolinar gets tranqued twice, the first case with "enough to knock out an elephant," it takes a minute before she's out.
** In one episode Daniel shoots Osiris with a tranq dart, and she pulls it out, looks annoyed, goes and activates some transporter rings, then leaves in a spaceship. The last shot of her shows that she's just a tad off balance, and that's about two minutes after getting shot. Note that he's using a Goa'uld-specific sedative.
** The same Goa'uld-specific sedative proves completely inefficient against Kull warriors, however, even though the trinium-tipped darts can pierce their special armor.
** In the later seasons, people are using tranq darts all the time and they often knock the victim out in less then a second, and occasionally cause the victim to throw themselves away from the dart.
* Played with in an episode of ''Series/StargateAtlantis''. Ford is hit with a dart, pulls it out and seemingly collapses immediately. The villains move in to restrain him, only for him to suddenly wake up and attack, indicating that he was either only stunned for a moment, or he may have been playing possum to draw them in.
* Subverted once on ''Series/TheRedGreenShow''. Ed Frid once shot himself in the foot with a tranquilizer dart and remained conscious long enough to calculate how long he would sleep, give Red instructions on how to deal with the animal they'd captured and lay down comfortably.
* Although Series/{{Dexter}} consistently uses a syringe up-close, there is one episode involving a tranquilizer dart. The target is an animal control worker who is holding a tranquilizer gun loaded to take down an alligator. Presumably resistant to the effect of tranquilizers from personal experience, he has enough time to shoot Dexter with it before he collapses. Dexter also has a bit of time to pull the dart out before losing consciousness. They both wake up in an ambulance with some really worried [=EMTs=].
* ''Series/{{Eureka}}'' equips Taggert, the Crocodile Dundee-esque dogcatcher, with these. Used twice, to take down FishOutOfWater Marshall Jack Carter, and inadvertently, the owner of the town's biggest (and possibly only) café.
* Subverted in ''Series/MalcolmInTheMiddle'', where trapped with a pair of lions, Malcolm shoots down the zoo personnel's idea of tranquilizing them on the grounds that the beasts would have just enough time to get angry and tear them apart (the show puts it at three minutes, which is almost certainly selling the lions short, but it's the thought that counts).
* ''Series/{{Chuck}}''
** Every time tranquilizers are used, unless the victim is BadassNormal Casey. When they have to tranquilize [[ThoseTwoGuys Jeff and Lester]], Lester goes down instantly but Jeff takes multiple darts and a few minutes to lose consciousness. Jeff is a bigger guy and his past drug use made him more resistant.
** The eponymous character himself is more wont to use tranquilizer darts as opposed to actual guns to (temporarily) take out bad guys. They ''always'' cause harmless InstantSedation.
* Subverted in ''Series/TheAdventuresOfPeteAndPete'''s ChristmasEpisode; Little Pete shoots the Garbage Man with a tranq (actually hitting a major vein!), and it takes a couple minutes of real-time to start taking effect.
* Subverted in ''Series/{{Friends}}'' when Phoebe is shot in the backside with a dart. She never passes out, though she does comment that her buttock is asleep (and that the other one has no idea). Of course, the dart was intended for a very small monkey, so there probably wasn't much juice in there anyway.
* An episode of the documentary series ''Series/FatalAttractions'' gave a good illustration of how these work in RealLife. When a man was discovered [[TooDumbToLive keeping a full-grown tiger in a New York City public-housing apartment]], a NYPD officer rappelled down from the roof with a tranquilizer gun to shoot the tiger through the window. When he did, the tiger immediately charged, hitting the wall with such force that the entire building shook. Only then did the tranquilizer take effect, enabling officers to safely remove the tiger from the building.
* In ''Series/TheIncredibleHulk'' IntrepidReporter Jack [=McGee=] at one point has a tranq gun to use on the Hulk. Sure enough, the Hulk shows up and [=McGee=] shoots him, to seemingly no effect even though he uses several darts. After the Hulk grabs and destroys the gun and runs off, he starts being affected.
* ''Series/BuffyTheVampireSlayer''
** Oz is a frequent victim of these, what with him being a werewolf. Over the course of the series he gets shot six times with a tranquilizer dart: "Phases", "Beauty and the Beasts", ''twice'' in "The Zeppo", "Wild at Heart" and "New Moon Rising".
** Giles gets shot with a tranquilizer dart meant for Oz when Buffy is thrown off the mark by the intended target's girlfriend.
** Willow shoots her vampire counterpart with one in "Doppelgangland".
* Tranquillizer darts are frequently used in ''Series/{{Primeval}}'' to stop creature attacks.
** Also used for that purpose on ''Series/{{Zoo}}'' when afflicted animals are being captured alive for research.
* ''Series/{{Batman}}'' episode "The Ring of Wax". The Riddler takes down Batman and Robin with anesthetic darts fired from a blowgun.

[[folder:Pro Wrestling]]
* In one episode of ''Raw'', the Big Show was shot by a tranquilizer dart used to take down dangerous animals. He may be a giant, but a rampaging deer still weighs more than twice his size. They didn't show a concern for him overdosing, but they did have him raging and ready to fight until it kicked in five minutes later so it's up to you to decide if this was played with, played straight, averted, inverted, or subverted.

[[folder:Tabletop Games]]
* ''TabletopGame/{{Shadowrun}}'' has darts filled with Neurostun or Narcoject, which can be fired from pistols and rifles.
* ''TabletopGame/D20Modern'' has the air pistol and air rifle, meant to deliver a tranquilizer round, though some characters don't hesitate to use more deadly payloads.
* ''TabletopGame/DungeonsAndDragons'' naturally has its share of this (especially in earlier editions with their plentiful save-or-die effects, where merely falling unconscious for an hour or two from a single failed saving throw could be considered positively merciful).
** The most iconic example are probably drow hand crossbows and their small but typically sleep drug-coated quarrels.
** ''Fiend Folio''. The red urchin fired spines tipped with a venom that put victims that failed a saving throw to sleep for 1-4 minutes.
* ''TabletopGame/{{Traveller}}'' had the snub pistol which could be loaded with tranquilizer rounds, as described in Book 4 ''Mercenary''. Any creature hit by one would be asleep shortly. In Adventure 2 ''Research Station Gamma'' the Animal Care Robots used them to capture escaped lab animals.

[[folder:Video Games]]
* ''VideoGame/DeusEx''
** Subverted in the first game. JC's mini-crossbow can be loaded with Tranquilizer Darts which take several seconds to subdue the target. And, furthering the subversion, the victim runs around yelling for help before falling unconscious. Though shooting them in the head plays it straight, earning you an instant knock-out. When the PC is shot with a tranquilizer dart, it causes the screen to darken and sway, but the nanotechnology takes care of the venom fairly rapidly. Of course the game is about lies and conspiracy and those tranquilizer darts are in all probability some form of lethal poison. Which is why YOU take damage when you are hit by them.
** But after an NPC finally drops, they lay out cold on the map perpetually.
** Adam Jensen continues, or rather set the precedent for JC to follow in ''VideoGame/DeusExHumanRevolution'', and has access to a tranquillizer rifle.
* Played straight and subverted in ''VideoGame/MetalGearSolid''. Hitting somebody in the head or the heart with the tranquilizing weapons (that is, not the stun grenades or the taser-like weapons) knocks out instantly while hitting the belly or the limbs delays the effect. Some of the boss characters are bizarrely resilient to tranquilizer rounds, though, and can take several rounds to the head before passing out, even though Otacon insists that the tranquilizer rounds are potent enough to knock out an elephant. It's worth pointing out that the same bosses can take a similar number of bullets to the head without dying.
* Played straight in the ''VideoGame/UltimateSpiderMan'' video game when Silver Sable tries to kidnap Peter Parker by knocking him out with a couple of tranquilizer darts... for a few minutes anyway. Then his enhanced metabolism kicks in allowing him to wake up earlier than he was supposed to and resist all subsequent shots. Cue boss battle where he has to fight off both Silver Sable and her mercenaries while trying not to succumb to the effects of the tranquilizers in his system.
* ''VideoGame/ShounenKinindenTsumuji'' has a blowgun that shoots darts causing enemies to be instantly knocked out and easy to attack.
* ''VideoGame/SecondSight'' has people staggering around for a few moments after being hit with tranquillizer darts,then reacting like they have been punched in the chest and falling over. Hitting them in the head takes them down instantly. It's worth noting that on the few occasions where you're shot with one yourself, it slowly saps your health rather than knocking you out (although the game treats knocked out enemies [[EverythingFades more or less]] [[RagdollPhysics the same]] as dead ones and [[spoiler:the cutscenes that play after you're defeated would indicate that you survive whatever takes you down]]).
* The Genesis version of ''JurassicPark'' limited Dr. Grant exclusively to non-lethal guns like tranquilizers, tasers, grenades and sedative-laced rockets, only the last of which put down dinosaurs indefinitely. The ActionizedSequel ''Rampage Edition'' added in some more deadly guns and removed the possibility for enemies to get back up (they'll still flash and disappear even if you are just using the tranq guns on them).
* In ''VideoGame/TheSeveralJourneysOfReemus'': Chapter two, Reemus is shot from offscreen by a dart so loaded with sedative that it actually sprays a considerable amount on Liam when it hits. Liam has just enough time to identify the sedative before he, too, is shot and goes under. Later on, they have to collect a sample of it (it's a type of honey made by a particular bee, which is so potent that even a small amount contains enough sugar to induce a temporary diabetic coma) to exploit its faux-sedative properties.
* Used frequently in the ''VideoGame/MonsterHunter'' series, with Tranq Bombs, Tranq S bowgun ammo, and even Tranq Throwing Knives, required for monster capture quests. The monster has to be weakened to the brink of death for them to work, and the effects will only kick in if the monster's in a trap.
* Ada Wong is knocked out by one in ''VideoGame/ResidentEvil4'' fired from a very archaic-looking air rifle. [[InstantSedation It takes her less than half a second from looking at the dart that hit her for her eyes to roll up into her head]].
* ''VideoGame/PerfectDark'' has a tranquilizer gun, but instead of knocking targets out, it blurs their vision, lowering their accuracy. The alternate fire gives the darts a lethal overdose.
* A stock weapon in the ''VideoGame/NoOneLivesForever'' series, essential in the levels where "no casualties" is the requirement.
* In the ''VideoGame/RuneScape'' quest "A Clockwork Syringe", if you're spotted during a StealthBasedMission, a dart will be thrown at you, the screen will turn black, and you'll wake up unharmed in [[CardboardPrison an unguarded jail cell which can be easily escaped]].
* ''VideoGame/{{Fallout 3}}'' has the Dart Gun, a makeshift crossbow that fires throwing darts (the kind used in pubs) tipped with radscorpion venom. The damage is pitiful, but it cripples the target's limbs completely, preventing them from moving or fighting effectively (note that radscorpion venom administered the natural way -- from a radscorpion stinger -- causes damage over time, not paralysis).
* The dart gun in ''VideoGame/FarCry2'' fires tranq darts meant for big game animals, and thus each shot result in an instakill.
* [[http://uncharted.wikia.com/wiki/Tranquilizer_Dart_Gun Such a gun]] is used in ''VideoGame/Uncharted2AmongThieves'' for one level by Drake and Flynn.
* In ''VideoGame/{{Borderlands 2}}'' Mordecai uses a tranq dart on Bloodwing after she is captured, experimented on and attacks the player, in an attempt to calm her down to bring her back to Sanctuary. This triggers possibly one of the saddest lines in the game:
-->'''Mordecai''': I'm loading the tranq dart! Tranquila Blood! This won't hurt, I promise.
* ''VideoGame/AlphaProtocol'' has tranquilizer rounds for the pistol, which does fixed (very low) damage against human foes (and even less so against body armour) with its only advantage being [[TechnicalPacifist that it counts as nonlethal incapacitation]]. They're even usable against bosses, although they will simply be treated as regular (but much less damaging) bullets against them and subsequent cutscenes will ignore said bosses being hopped up on enough tranquilizer to put a herd of elephants to sleep. [[spoiler:This means that if you bring down Darcy with them in the endgame, he'll presumably suffer an allergic reaction to them since he dies anyway.]]

[[folder:Web Comics]]
* Subverted and Lampshaded in ''Webcomic/TheLastDaysOfFoxhound''. When [[spoiler:Liquid is possessed by Big Boss]] and he is threatening Raven, he is shot in the head with a high dosage tranq dart by Wolf, and it takes him several seconds to fall unconscious, causing Raven to say "That took ''way'' too fucking long". Also subverted when the Cyborg Ninja is tranquillized and remains conscious long enough to flee.
-->'''Wolf:''' I can never get ze dose right vith zese super-humans.
* Webcomic/DominicDeegan has [[http://www.dominic-deegan.com/view.php?date=2010-08-19 instant paralysis]] darts that, bizarrely wear off moments after being removed.

[[folder:Web Original]]
* In the end of WebVideo/TheNostalgiaCritic's review of ''WesternAnimation/{{GrandmaGotRunOverByAReindeer}}'', he goes briefly insane, singing a terrifyingly Christmas-joy-filled song, before being shot with a tranquilizer dart. [[SubvertedTrope Subverted]], in that he says he loves Christmas so much, that he can build tranquilizer immunity.
* In ''WebAnimation/DeepSpace69'' episode 18:
--> '''Jay:''' Imma take a nap on the ground. ''(faints)''

[[folder:Western Animation]]
* ''WesternAnimation/TheFairlyOddParents'': After recalling all that Cosmo had done to ruin his career, [[DrillSergeantNasty Jorgen von Strangle]] goes into a fit of animalistic rage only to be quickly rendered insensate using two darts humorously marked "K" & "O".
* ''WesternAnimation/JonnyQuest'' TOS episodes:
** "The Quetong Missile Mystery". In what may be a LampshadeHanging, Race Bannon makes a note of how fast anaesthetic darts work on enemy guards.
** "Pirates from Below". Race and Bandit are knocked out by a tranquillizer dart rifle wielded by an enemy operative.
* ''WesternAnimation/FamilyGuy''
** In an early episode, Peter's boss devises a contest for the company picnic, which involves taking shots at the employees with a tranq rifle and seeing who can last the longest. Most of the employees drop like stones the moment they get shot... except for Peter, who ends up with more than a ''dozen'' tranquillizer needles stuck in him, and still manages to stay conscious long enough to win the contest. It would seem that this is either due to his relatively high body mass, which (in theory) would require longer for the chemicals to spread through his body, or due to the increased amount of fatty deposits, which would help isolate the venom from his bloodstream.
* ''WesternAnimation/TheVentureBrothers''
** Subverted in the first episode; Brock takes about a dozen butterfly darts, and only goes down when hit with a truck. Of course, [[MadeOfIron it]] ''[[MadeOfIron is]]'' [[MadeOfIron Brock]].
** The pirate captain has an addiction to tranquillizer darts in the episode "The Lepidopterists."
** 24's attempt to kill Hank in the episode "Tears of the Sea Cow" are averted because he didn't know his rifle only shot tranquillizer darts.
* ''WesternAnimation/TheSimpsons'': In the Season One episode ''The Call of the Simpsons'', Homer is mistaken for Bigfoot and hit with a tranquilizer dart. He has enough time to say "Avenge my death, son," before falling asleep, snoring noticeably.
** Bart has just been "taken" by a monkey at a local zoo, and Homer tries to save him by putting a tranq-dart into a tube and putting it into his mouth. He then inhales, and it gets self-explanatory after that.
** Subverted in another episode when Barney is shot with a ''bear'' tranquilizer dart. He actually pulls out the dart and drinks the remaining sedative before passing out.
* Subverted in a ''WesternAnimation/TheRenAndStimpyShow'' cartoon parodying nature shows; [[HairTriggerTemper Ren]] is accidentally shot with a tranq dart by [[TheDitz Stimpy]], and it takes a minute for him to go down. In the meantime, [[RuleOfFunny his voice slows down]].
* In ''WesternAnimation/{{Gargoyles}}'', when Brooklyn is hit with one, he goes down almost instantly, but is still blinking groggily when he's dragged away -- so it may not have put him out completely at all. Goliath gets hit with one in Awakening Part III which only slows him down for awhile.
* ''WesternAnimation/CodenameKidsNextDoor'': Used in "Operation: Z.O.O." by Mrs. Goodwall (a parody of Jane Goodall) against the KND, to put them in a "Kids Zoo".
* Used in three episodes of the ''WesternAnimation/TotalDrama'' series:
** In "Wawanakwa Gone Wild!", Izzy uses them in a gun to try and bring down the animal she has to capture, a deer. Unfortunately, Heather is hiding behind a bush wearing deer antlers -- Izzy only sees the antlers and shoots her by mistake.
** In "Search and Do Not Destroy", Owen comes back to the campgrounds sticking out of a bear's mouth. Chris uses the darts to sedate the bear, but he gets Owen, too.
** In "Dial M for Merger", Duncan gets shot in the neck with a dart when the interns have to drag the remaining contestants to a cave as part of the challenge.
* Subverted in a ''WesternAnimation/{{Futurama}}'' episode. A mysterious [[spoiler:robot]] in a robe tries to shoot a dart at the Professor, but misses and hits [[RidiculouslyHumanRobots Bender]].
* The villains used such darts in a ''WesternAnimation/TheLegendOfKorra'' episode to knock out and kidnap the titular heroine. They launched them with their bending in lieu of the traditional guns, though.
* Animal Control from ''WesternAnimation/RegularShow'' use assault rifles loaded with tranquilizer darts to bring down Death Bear. It works; About 2 minutes, 300 darts and one pair of arms later.
* In an episode of ''WesternAnimation/HouseOfMouse'', Donald tries to shoot tranquilizers at the Aracuan Bird during his performance, eventually using [[MoreDakka heavier firepower]] in all directions. By the time he's done, everyone in the club, including Mickey and ''Donald himself'' is shot and fast asleep...[[{{Irony}} except]] [[Disney/SleepingBeauty Princess Aurora]].