[[quoteright:300:[[Creator/MartenEskilWinge http://static.tvtropes.org/pmwiki/pub/images/06lyx73z-2_7932.jpg]]]]
[[caption-width-right:300:[[Literature/TheSagaOfArrowOdd Hjalmar and Orvar-Odd]]]]

This trope refers to a specific {{plot}} that is OlderThanDirt. In it, two [[AlwaysMale heroes]] are [[HeterosexualLifePartners intensely close friends]]. Unfortunately, one of them (usually [[{{Deuteragonist}} the one who's not the main character]]) dies during the course of the story. The death has a profound effect on the remaining hero, and changes them forever.

It's important to note that
# The two cannot just be friends or acquaintances. They have to be [[HeterosexualLifePartners REALLY close]], and
# The character's [[AnyoneCanDie death]] needs to be a huge turning point in the story.

!As a DeathTrope, many if not all spoilers will be unmarked ahead. Beware.
! Examples:
%% Zero Content examples have been commented out. Please write up a full example before uncommenting.


[[folder:Anime & Manga]]
* ''Manga/FullmetalAlchemist'': Roy Mustang and Maes Hughes were friends ever since the Academy times, survived the cruel Ishbalan war, discussed the mental wounds left by the horrible shit they witnessed there, and decided to do their best to keep Amestris peaceful. Then Hughes was murdered [[HeKnowsTooMuch after he learned the villains' plans]] and Roy was ''deeply'' affected by that...
* ''Anime/TengenToppaGurrenLagann'': Simon and Kamina. They consider each other brothers, despite not being blood related, and Kamina's death in battle almost breaks Simon's mind. While he eventually recovers, he never forgets Kamina's huge influence in his life.
%%* ''Manga/NabariNoOu'': Miharu and Yoite.
* ''Anime/LegendOfGalacticHeroes'' has two of these, both of epic proportions:
** Reinhard and Kircheis. They were childhood friends, and Kircheis became Reinhard's first follower, his closest (only, in fact) [[OnlyFriend friend]], [[NumberTwo trusted confidant and right hand man (being quite brilliant on his own right)]], [[TheConsigliere providing good advice and overall having a tempering effect on Reinhard]]. His murder that takes place in front of Reinhard's eyes (as Kircheis is shielding him from an attack) is [[HeroicBSOD such a blow to Reinhard]] that he never completely gets over it, and Kircheis' loss is felt keenly through the rest of the story. To hammer the point home, Kircheis' first name is "Siegfried", and Reinhard is associated with "Brunhild" (the name of his flagship that he always uses to travel).
** Reuenthal and Mittermeier. They were [[OddCouple unlikely friends]] who nevertheless became very close, and very loyal and attached to each other; eventually their friendship and military prowess earned them the nickname "The Twin Stars of the Empire". As the years went by and Reuenthal's already dark psyche became even darker and more conflicted, Mittermeier became [[LivingEmotionalCrutch the only one anchoring him and keeping him in line as much as possible]]. In the end due to circumstances and Reuenthal's darker thoughts getting the better of him, he betrays Reinhard, and in a cruel twist Mittermeier is ordered to subdue him, breaking his heart. To further twist the knife, Reuenthal was always associated with Tristan (the name of his flagship), and his death has ''TristanAndIsolde'' parallels as he's clinging on to life hoping to see Mittermeier one last time. Their TragicBromance ends on a bittersweet note: Mittermeier adopts Reuenthal's orphaned infant son, giving him the loving family that his friend never had.)
* ''Anime/PuellaMagiMadokaMagica'': GenderFlipped with Homura and Madoka [[AlternateTimeline in the original timeline]]. Madoka dying prompts Homura to contract, wishing to be able to [[TimeTravel go back and protect her]]. This has the unintended side-effect of making Madoka increasingly important to causality, [[GoneHorriblyWrong making Kyubey try even harder to contract her]] and setting off the entire plot of the series.
* ''Anime/CodeGeass'': They put each other through [[WeUsedToBeFriends absolute hell]] first, but Lelouch and Suzaku's reconciliation at the end implies they've come to an understanding of each other. Lelouch's ThanatosGambit at the end of the series changes the course of Suzaku's life forever (and, ironically, gives him a reason to keep living)as well as the world.
* ''Manga/SevenSeeds'' has Aramaki Takahiro and Saejima Fubuki. Both are part of Team Winter and, before being drafted for the project, they were on different baseball teams but knew of each other and ''really'' wanted to meet each other. When they finally do, they immediately strike up a friendship and become as close as brothers. Unfortunately, Fubuki dies shortly after they become friends and Aramaki [[DeadGuyJunior named one of the two puppies that accompany him after Fubuki]].
* ''Manga/DeathNote'' features a bizarre example: [[PersonOfMassDestruction Light]] and [[SympatheticInspectorAntagonist L]] are, on many levels, the only people capable of [[IntelligenceEqualsIsolation understanding one another]], and spend several months literally [[ChainedHeat attached to each other]] twenty-four/seven; ultimately, though, Light [[CradlingYourKill kills L]] for the sake of his [[UtopiaJustifiesTheMeans 'new world']]. This is a definite [[KickTheMoralityPet turning point of the story]]; from that point onward, Light's mental instability reaches [[MoralEventHorizon a whole new level of horrific]]. Had they met under different circumstances, their bromance would've been a lot less tragic.
* In ''Anime/HeatGuyJ'', Clair's EliteMook and friend Ian is killed after a fact-finding mission gone wrong, and just hours later Mitchal blows himself up (ostensibly to allow Giovanni and Clair to make a getaway from their enemies, though part of it may have been so he and Ian could be TogetherInDeath). All Clair has left of them are Mitchal's "lucky" dice and Ian's Phi Beta Kappa ring. This (coupled with losing his [[TheDon Vampire]] status and his home, plus the Daddy Issues he had from the start) sends him into an AngstComa.
* In ''Manga/ZeroSevenGhost'', Mikage is the {{only friend}} that Teito has. Mikage likewise is very attached to Teito and fiercely protective of him. After a few plot events, [[BigBad Ayanami]] hijacks Mikage's body and irrepairably destroys his soul. Frau is forced to kill him to save Teito's life. It's worse, in that Mikage dies smiling in Teito's arms before dissolving into feathers. It's made better/worse, depending on the viewer, when Mikage's soul is reincarnated into the cutest bunny-dragon you ever did see.
* ''Manga/AttackOnTitan'' has [[JerkWithAHeartOfGold Jean]] and [[TheHeart Marco]], who become close friends during their three years in training together. Both dream of joining the Military Police Brigade, but for very different reasons and are opposites in terms of demeanor. However, Marco recognizes and encourages Jean's potential as TheLeader, seeing in him someone capable of much more than he's [[YouAreBetterThanYouThinkYouAre willing to believe]]. During the gruesome cleanup of Trost in the aftermath of the battle there, Jean discovers [[HalfTheManHeUsedToBe what remains]] of Marco. The meaningless and lonely death of his best friend prompts Jean to abandon his selfish ideals, and enlist in the Survey Corps where he quickly establishes himself as a capable young leader. When the others joke wondering [[OOCIsSeriousBusiness what happened]] to the Jean they all knew, he states his intention to not disappoint [[MeaningfulFuneral those charred bones]] he saw.
** Then there are Eren and Armin, whose relationship was far closer and more intense in the manga than in the anime. Armin, brilliant but physically weak, often doubted his self-worth in his DoomedHometown and in the physically-demanding soldier training he and Eren both went through. Eren saw his friend for the genius he was, and constantly put himself in harm's way to protect Armin - to the point of jumping into a Titan's mouth to save Armin, sacrificing his life in the process. Of course, he got better, but that moment where he watched helplessly as his best friend died for him changed Armin forever. From then on, he started volunteering to come up with crazy strategies that had a habit of working; he saved the world far more effectively than even Eren did, just by trusting in his own strength like Eren had. But the truly tragic part of this friendship happens much later in the manga, when [[spoiler: Armin ([[NotQuiteDead briefly]]) gives up his own life so that Eren can defeat the Colossal Titan. He just saved the world, changing everyone's lives irrevocably...but the look on Eren's face shows just how shocked and heartbroken he is to lose his oldest and closest friend]].
* ''Anime/RebuildOfEvangelion'': The third installment is a big TraumaCongaLine for Shinji, but what finally breaks him is the death of Kaworu, the only person in the film who was genuinely nice to him.
** Their relationship counts in the [[Anime/NeonGenesisEvangelion original anime]] and its manga adaptation as well. [[BroadStrokes The details differ in each continuity]], but all three incarnations involve an intense relationship between the two which ends in Kaworu's death, driving Shinji deeper into despair.
* Waver and his [[SummoningRitual Servant]] Rider from ''LightNovel/FateZero'', despite only knowing each other for a few weeks, forge an intense friendship which culminates in Waver pledging his UndyingLoyalty to Rider shortly before the latter is killed by Gilgamesh (whose ''own'' tragic bromance with Enkidu is alluded to afterwards). Waver undergoes tremendous CharacterDevelopment due to his friendship with Rider and is deeply influenced by his Servant's ideals for the rest of his life. Considering Rider is ''the'' UsefulNotes/AlexanderTheGreat, this isn't surprising.
** [[RaisedAsTheOppositeGender Saber]] and Lancer comes across like this, despite being opposite genders. The two of them share the same code of ethics in a conflict which doesn't have a place for their knightly chivalry, and while they are enemies [[EnemyMine for the most part]], they connect more strongly to each other than to anyone else. Lancer's death is a pivotal moment in her character arc, and without him there is no one who truly understands and respects her.
* ''Franchise/{{Gundam}}'' really loves this, mostly to show that WarIsHell.
** Played a lot in ''Anime/MobileSuitGundamSEED''. The series mainly revolves around ChildhoodFriends [[TheHero Kira Yamato]] and [[TheDragon Athrun Zala]] having to reluctantly fight each other due to ending at two warring factions. Then came the time when Kira kills a close friend and comrade of Athrun in combat, who in turn becomes furious and retaliates by killing one of Kira's TrueCompanions. Said killings resulted with the two former friends having a battle to the death which Athrun won, but said victory is more like a PyrrhicVictory as he becomes emotionally damaged as a result. However, Kira survives their encounter. Not only that, but Athrun's fiancee also helped him steal one of their faction's [[BiggerStick top mobile suits]]. Once he learns this, he was ordered to reclaim or destroy the stolen unit by piloting another one of those top MS. By this time, Athrun has become very aware that WarIsHell and pulls a HeelFaceTurn and [[BashBrothers reunites and reconciled with his friend]] and [[MeleeATrois join/create a third faction]] to stop it.
*** The original planned ending of the series had ''[[TheHeroDies Kira dying]]'', with Athrun [[AnArmAndALeg losing an arm]] and being emotionally damaged.
** In ''Anime/MobileSuitGundamAGE'', the series' second protagonist (it's a GenerationalSaga) Asemu Asuno eventually have to fight his best friend Zeheart Galette, who is TheMole of the other faction. Obviously, both guys have a hard time dealing with having to fight each other, especially Asemu. Ultimately, Asemu ended up having to kill Zeheart, but not long before having a final heartfelt conversation. Their friendship is much more emphasized in the show's [[LimitedSpecialCollectorsUltimateEdition Special Edition]].
* ''Anime/{{K}}'' has the something like a domino example:
** The founding trio of HOMRA: Izumo, Mikoto and Tatara - particularly the last two. They became good friends in their teenage years, and after Mikoto became the Red King, the other two became his first Clansmen, and Tatara helped him deal with his nearly uncontrollable powers. Tatara is murdered, and it very obviously effects Mikoto's psychological state. He becomes a DeathSeeker whose only goal is fiery, violent revenge on the killer, despite the fact that his own powers are going haywire - which he knows will cause [[SuperPowerMeltdown large-scale destruction]] if that's allowed to happen, and the only way to stop it is for someone to kill him.
** Mikoto and Reisi have this dynamic as well. Though the two fight constantly, it's clear that they care about each other, and spend the series trying to find a way to prevent Mikoto's powers from destroying the city and himself. [[spoiler: Mikoto chooses Reisi to be the one to kill him to prevent the aforementioned SuperPowerMeltdown, potentially causing Reisi to lose control of his powers in the same way. Reisi spends the second season grieving for Mikoto while dealing with that possibility.]]

[[folder:Comic Books]]
* Creator/DCComics
%%** ''ComicBook/{{Hitman}}'': Tommy and Ringo, Tommy and Pat, and Hacken and Ringo. A case could be made for Tommy and Bob as well.
** ComicBook/BoosterGold and Ted Kord's ComicBook/BlueBeetle, though in some continuities, Jaime Reyes' Beetle serves as ReplacementGoldfish. Beetle's death makes Booster go from an egotistical, fame-seeking buffoon to wanting to genuinely be a heroic hero who contributes something.
** Though he got better, Franchise/GreenLantern Kyle Rayner's death in the ComicBook/BlackestNight story arc caused his close friend and colleague, Guy Gardner, to break down in tears for a moment before entirely giving in to his maddened rage and becoming a Red Lantern.
* Creator/MarvelComics
** ''ComicBook/CaptainAmerica'': Steve Rogers and ComicBook/BuckyBarnes. The Cap seemed broken when Bucky died back in the war and at present, he found out the hard way that Bucky is still alive except he's Comicbook/WinterSoldier who is brainwashed by HYDRA. And when Steve died after the end of ''Comicbook/CivilWar'', Bucky takes it hard and tries to find those responsible for his assassination. Later on, Bucky takes the shield and the name of Captain America as a way to continue his best friend's legacy.
** Captain America and [[Comicbook/IronMan Tony Stark]]. Their friendship was destroyed no thanks to a certain SuperRegistrationAct which sends them and the rest of the superheroes as [[Comicbook/CivilWar a ruthless battle between those who support and those who are against the act]]. In the end, the Cap surrenders and the pro-regs win but with a price: HYDRA took this opportunity to kill the Cap which they succeeded. As a result, Tony mourns the death of his once close friend and couldn't give a proper farewell speech during his funeral, letting the Falcon do the honors.

* In ''Film/ForrestGump'', Forrest and Bubba. After Bubba's death, Forrest fulfills his friend's lifelong dream by buying a shrimping boat.
%%* Several Creator/JohnWoo films
%%** ''Film/ABetterTomorrow'': Sung Tse Ho and Mark Gor
%%** ''A Better Tomorrow II'': Sung Tse Ho and Sung Tse Kit.
%%** Inverted in ''Film/TheKiller'' with Ah Jong and Inspector Li Ying
%%** ''Film/HardBoiled'': Tequila Yuen and Alan
* ''Brian's Song'': Brian Piccolo and Gayle Sayers, due to Brian's death from cancer. Doubles as a Real Life example.
* An epic ''womance'': the two female scientists from ''Film/{{Volcano}}''. The remaining scientist (Anne Heche) is that much more determined to convince [=FEMA=] that there's really a volcano starting in Los Angeles because her best friend died to prove it.
* Similarly, the death of her close friend and fellow CIA agent in the line of duty causes the main character of ''Film/ZeroDarkThirty'' to adopt an [[ItsPersonal It's Personal]] stance on the search for Bin Laden.
* Obi-Wan Kenobi and Anakin Skywalker share this fate throughout the ''StarWars'' saga, though their tragedy isn't either one's literal death, but that Anakin is [[MetaphoricallyTrue "killed by Darth Vader"]] (and eventually kills Obi-Wan).
* In the Franchise/MarvelCinematicUniverse, this is the center of an arc between Steve Rogers and James "Bucky" Barnes. Buck's ([[BackFromTheDead apparent]]) death in ''First Avenger'' shakes up Steve, and they can't fully go back to their previous relationship because of his bloody past as the Winter Soldier, which is either brought up or exploited by the antagonists when relevant. Ultimately, [[spoiler: he decides to put himself on ice]] at the end of ''Film/CaptainAmericaCivilWar'' until his brainwashing is completely flushed out.
* ''Film/DeadPoetsSociety'' has [[BrokenAce Neil]] and [[ShrinkingViolet Todd]] who are roommates and best friends at 'Hellton'. Throughout the movie, they support each other's fight against their controlling parents. Eventually, Neil is cowed by his father and commits suicide, leaving Todd openly distraught and heartbroken.
* In ''Film/{{Star Trek II|The Wrath of Khan}}'', Kirk has to watch his friend Spock die. Of course, in the next movie Spock gets better, but at the time it was intended to stick.
* A variation of this happens in ''Film/XMenFirstClass''; Erik Lehnsherr and Charles Xavier form a close friendship, but [[ForegoneConclusion ultimately part]] because of a major difference in ideals. Notably, neither is killed, although [[spoiler:Professor X does sustain a permanent injury that leads to Magneto [[CradlingYourKill cradling his cripple]]]].
* In ''Film/TopGun'' the death of Maverick's GuyInBack and volleyball partner Goose is a major turning point in the characters life.
%%* Inverted in ''Film/TheWindThatShakesTheBarley'' with Damien and Teddy O'Donovan.
* Happens to Thor and Loki in ''Film/{{Thor}}'' when Loki commits suicide, since although he doesn't actually die, Thor doesn't know that.
* ''Film/MidnightCowboy'': Ratso dies after he and Joe Buck spend the film becoming VitriolicBestBuds.
* In the ''Film/{{Watchmen}}'' movie, Nite Owl II [[AdaptationalAngstUpgrade sees]] Rorschach's death and it visibly crushed him, which ultimately caused him to lash out at [[BigBadFriend the person]] directly responsible for it.
* ''Film/BeastsOfNoNation'': [[spoiler:Strika becomes Agu's [[OnlyFriend only friend]] while serving as child soldiers in the NDF. When Strika dies, there's nothing holding Agu to the NDF anymore]].
* ''Film/TheLivingWake'' is all about K. Roth's last twelve hours to live, and his best friend Mills helping him arrange his own funeral. The two are impossibly close friends (and, indeed, each other's ''only'' friends), and Mills' [[ThePollyanna sunny disposition]] only cracks twice: when he's delivering his eulogy for K. Roth ''to'' K. Roth, and [[spoiler:when K. Roth finally dies at the end of the film. Mills' despair is heartbreaking]].
* In ''Film/AChristmasCarolTheMusical'' Scrooge and Jacob Marley were genuinely good friends. The first thing Marley's ghost does upon appearing is burst into tears and hug Scrooge, and later, Scrooge is distraught at having to relive Marley's death in the Past sequence. Ruthless though he already was beforehand, we get the sense that Marley's death was the last straw that fully hardened Scrooge's heart.

%%* ''Literature/ASeparatePeace'': Gene and Finny
* In ''Literature/DragonBones'', Ward has to kill Oreg, whom he loves like a brother, in order to enable an HeroicSacrifice. When he feels Oreg's last breath on his cheek, he thinks that it feels warm, but ''he'' will never feel warmth again, ever.
* ''Literature/HarryPotter'' gives us James Potter and Sirius Black. They were a part of a four-person group of friends at Hogwarts called the Marauders, but they were described as being the Fred and George Weasley of their time. When James dies at the hands of Voldemort, Sirius was ready to relinquish his rebellious lifestyle to look after James' son Harry, but when Hagrid mentioned that Dumbledore already had a plan in place, Sirius unsuccessfully went after the man responsible for allowing Voldemort to kill his friend, which got him wrongly imprisoned. Ever after both James' death and his imprisonment in Azkaban, he isn't nearly as cheerful or light-hearted as he is presented in flashbacks or in a little side-story, though he does briefly revert to his old self when he comes into possession of his old house.
* ''Literature/TheGreatGatsby'': Nick and Gatsby, certainly by the end of the book.
* Landen Parke-Laine and Anton Next in the ''Literature/ThursdayNext'' series. Especially tragic because Landon's (truthful) testimony in the investigation of the events that killed Anton turned Anton's name to mud for all history.
* Literature/SherlockHolmes and Watson, when Holmes apparently dies in ''The Final Problem''. Luckily, [[HesJustHiding he was just hiding]].
* ''Literature/TheSilmarillion'': Turin and Beleg, immortalized in-universe by the "Song of the Great Bow." The tragedy is made even worse by the fact that Turin [[AccidentalMurder was the cause of Beleg's death]]!
* ''Literature/DragonLance'': Raistlin's ascension to the tower of high sorcery leaves Caramon a drunken wreck for years. Without his brother, he felt completely unneeded. It is only after Raistlin actually dies that he is able to move on with his life.
* While Robert is no longer a main character by the third book in ''Literature/TheEmigrants'' suite him and Arvid still fit this trope. Arvid's death on their way to California has a deep impact on Robert and he never recovers.
* ''Literature/ASongOfIceAndFire'':
** Lord Jon Connington and the late [[TheWhitePrince Prince Rhaegar]] in ''Literature/ADanceWithDragons''. Connington is particularly ashamed of losing a crucial battle against Robert Baratheon, who would go on to kill Rhaegar, take the throne, and exile Connington.
** Jenny of Oldstones and the Ghost of High Heart are a rare female version. They were best friends back during the reign of King Aegon V, and Jenny even brought the Ghost to royal court with her when she married Prince Duncan the Small. Its unknown how or when Jenny died, but the Ghost long outlived her and is still very torn up about it. In exchange for telling people about her prophetic visions, the Ghost demands to be sung the song that was written about Jenny.
* ''Literature/MalazanBookOfTheFallen'':
** In the last volume of the series, [[ThePrankster former prankster]] Silchas Ruin and [[TheQuietOne war veteran]] Kagamandra Tulas Shorn are revealed to have been very close friends before the civil war. Politics saw them end up on opposing sides, but when Tulas inexplicably disappeared, presumed dead, Silchas Ruin was so devastated even his WarriorPrince brother Anomander Rake took out some time from trying to save the realm to help Silchas Ruin look for Tulas' corpse -- although later Silchas comes to the conclusion that his brother was the one to kill Tulas to begin with. Eventually, the series' final volume sees a tearful -- and [[VitriolicBestBuds manly snarky]] -- reunion, with Tulas, [[TheUndead now undead]], having escaped the Realm of the Dead, and they fulfill their hearts' wish to [[BashBrothers fight side by side]] in the series' final battle, where Tulas dies a second and final time at Silchas Ruin's side.
** Icarium Lifestealer and Mappo Runt have been HeterosexualLifePartners for centuries, wandering the world together, and are close enough to openly speak about their deep feelings of friendship. Even though Mappo was originally meant as a guardian and minder for Icarium, Icarium's generous and noble nature makes Mappo cherish him. Despite having severe problems with [[TraumaInducedAmnesia memories]], Icarium can by the feeling of familiarity alone tell that Mappo is indeed the friend he claims to be. When they are attacked and separated, Mappo crosses half the world to find Icarium again, only to die mere metres away from his closest friend. However, it is heavily implied that this is the turning point for Icarium and the latter finally regains at least some of his memories, enabling him to take his life back into his own hands.
** Zig-zagged with Trull Sengar and Ahlrada Ahn. They are set up for a bromance alright. Both are able warriors who have trained together and opposed the Unification Wars and, by Trull's admission, really ought to be close friends. But Ahlrada is [[TheMole a mole]] and deathly afraid of being found out, while Trull is [[NoSocialSkills no good at reading social cues]]. He spends most of the fifth book wondering why Ahlrada hates him so much, while Ahlrada comes to [[HeroWorship worship Trull's courage]]. Eventually, Ahlrada goes as far as being involved in [[TheExile Trull's imprisonment and banishment]], then spends most of the sixths book wracked by guilt over it. When they do meet again, it's in the middle of a battle on opposing sides and Ahlrada promptly deserts his command and begs Trull's forgiveness, only to be cut down and to die in Trull's arms, leaving Trull to wonder what the heck just happened. Neither ever finds out how close they were without ever being able to call each other friend.

[[folder:Live Action TV]]
* ''Series/{{Supernatural}}'': The two leads Sam and Dean Winchester manage to do this to one another ''multiple times''. Dean is the ruling champion, but if it weren't for Sam's first major death the whole plot from the beginning of season three onward would not exist in any recognizable form.
** [[DealWithTheDevil Getting him out of it]] caused Dean to die at the end of season three, which caused Sam to have a [[DarkerAndEdgier major character shift]] in the four months between then and when Dean got better again at the start of season four; and the combination of what the two of them did ''while'' Dean was dead set up the [[HeroicSacrifice need]] for Sam to [[RedemptionEqualsDeath die]] at the end of season five. Dean followed Sam's "last request" to try and live a normal life, but was ''pissed'' when Sam shows up again and reveals he's been back for a while without telling him. Then it turned out Sam's ''soul'' was still stuck in Hell...
** Dean's 101 deaths during one season three episode hit Sam pretty hard, too, especially the one that last six months before the bastard undid it. And hence the title of reigning champion. Also the fact that he stayed dead the longest.
** Dean and Castiel over the course of seasons six and seven. After Cas's power-trip and ensuing "sacrifice", Dean spends half a season going through the motions like season-six-Buffy, unable to really care about himself or the state of the world, and only starting to recover after Castiel reappears.
--> "You know, I used to be able to just shake this stuff off. You know, whatever it was. It might take me some time, but... I always could. What Cas did... I just can't – I don't know why."
** Dean really can't catch a break from this trope. If it isn't Sam, it's Cas. If it isn't Cas, it's Benny.
* Although Buffy gets better by the end of Season 6, Buffy and Willow between the season 5 finale and the season 6 premiere of ''Series/BuffyTheVampireSlayer'' totally fits this trope. Buffy's death causes Willow to go into a spiral of desperation and bargaining that eventually leads her into [[KnightTemplar extremely morally ambiguous territory]] in her effort to resurrect her best friend, leads to her sliding into DrunkWithPower, and emotionally sets her up for a DespairEventHorizon after her unrelated ''romantic'' tragedy one season later. By the time of season 8, Willow is trying to keep Kennedy isolated from Buffy because she believes that, had she not resurrected Buffy, Tara would still be alive. However, during the ''Angel & Faith'' arc "Family Reunion," Willow tells Angel that, despite all of the pain and angst that the Scoobies went through as a result, she has ''never'' regretted bringing Buffy back to life for a second.
* ''Series/ShutUpFlowerBoyBand'' has one of the members of the titular band die in a tragic fashion. [[AgeAppropriateAngst Being teenagers]], the rest of the band doesn't take his death too well.
* Horatio and Archie's friendship in the ''Series/HoratioHornblower'' miniseries was extremely deep. They were together in purgatory (Horatio's first ship ''Justinian'' where they both got bullied and tormented by a sadistic midshipman), got separated and met again in hell, a Spanish prison when they both got tortured in a PunishmentBox and Archie [[DrivenToSuicide tried to starve himself]]. Horatio saved Archie's life when he nursed him back into health, and Archie saved Horatio's when he dragged him from an exploding bridge during a doomed mission in France. In "Retribution", Horatio is shattered by Archie's [[AlmostDeadGuy slow and painful death]] and his HeroicSacrifice. However, the emotional fallout after Archie's death isn't explored overtly in the subsequent series, but Hornblower is obviously a man who is bitter and surly, without a pal [[SugarAndIcePersonality who could make him show his more cheerful and pleasant side]]. [[note]]This was all done quite possibly due to ExecutiveMeddling because Forester's estate wanted Hornblower to be turned back again into "a hero alone" which is who he is in the books. They also insisted that Archie, a CompositeCharacter, is written off, and Hornblower becomes paired with his canonical best pal, Lieutenant Bush, whose friendship is less tight.[[/note]]
* ''Series/{{Merlin}}'' ends with Arthur dying in Merlin's arms and Merlin believing that he's failed in his destiny to protect him. Scant comfort is derived from his [[PlatonicLifePartners very close friendship with Guinevere]] Arthur's widow and the sole ruler of Camelot and the Great Dragon's promise that one day Arthur will return in the time of Britain's greatest need. A FlashForward shows Merlin as a hobo in modern times, still waiting for Arthur's return.
* This seems to be a thing that happens towards the finale of many a Heisei-era ''Franchise/KamenRider'' show between the protagonist and the deuteragonist.
** ''Series/KamenRiderRyuki'': In the second to last episode, Shinji/Ryuki is dealt a fatal wound by a group of Monsters and his death prompts Ren/Knight to attempt to become the Final Rider.
*** In the 13 Riders special, the roles are reversed.
** ''Series/KamenRiderBlade'': Kenzaki/Blade sacrifices his humanity to become a Joker Undead in the finale, but as a result, must separate himself from Hajime/Chalice.
*** In TheMovie, the roles are reversed with Hajime sacrificing himself in place of Kenzaki.
** ''Series/KamenRiderDouble'': Philip disappears at the conclusion of the second to last episode, leaving Shotaro to protect Futo as Kamen Rider Joker. Fortunately, Philip is revived in the final episode.
** ''Series/KamenRiderOOO'': Ankh's Core Medal is cracked by Maki, but decides to help Eiji/OOO defeat the latter. After defeating Maki, Ankh dies, although his spirit is seen to follow Eiji.
* ''Series/{{Smash}}'': Kyle is the only person Jimmy seems to genuinely love, but he's a jerk to him too. Then Kyle is killed in a hit-and-run, and Jimmy cleans up his act, dedicates himself to their musical, sobs when Kyle wins a posthumous Tony, and fesses up to a past crime and does time so he can start fresh.
* ''Series/SonsOfAnarchy'': Opie's death, which was a combination of [[SuicideByCop Suicide by Prison Gang]] and HeroicSacrifice was the final straw for Jax Teller. After four seasons of contemplating leaving the club, he throws himself full on into the dirty dealings, and onto the ProtagonistJourneyToVillain path.
* ''Series/TheWalkingDead'': Due to Shane being SparedByTheAdaptation, his LoveTriangle with his best friend Rick and the latter's wife Lori is fully utilized. Rick and Shane are the best of friends since high school up until the day they became cops. On one mission, Rick is shot and was put in a coma. During this time, the ZombieApocalypse happened and Shane had to take care of Lori and her and Rick's son Carl. Thinking that Rick is dead, Shane and Lori began a relationship. Once Rick returns to the scene, Lori obviously abandons Shane. Shane, while initially happy to see Rick alive, [[LoveMakesYouEvil gradually becomes resentful]] towards him and [[LoveMakesYouCrazy comes to believe that he is a better husband and father than him]]. The second season shows the dissolution of their friendship, with Rick ultimately having to kill Shane because [[SanitySlippage he has gone to the deep end by that point]]. Having to kill Shane made a huge impact on Rick's CharacterDevelopment in later seasons.

* ''Manhwa/CielTheLastAutumnStory'''s Yvienne and Lariatte form another GenderFlipped version, with Lariatte's HeroicSacrifice causing Yvienne's DespairEventHorizon.

* Music/{{Horslips}}' retelling of Irish primal mythology, ''The Tain'', has the ballad ''[[https://www.youtube.com/watch?v=eHAsDJlG0zs Cuchulain's Lament]]'' in which the hero comes out of a battle-frenzy to realise he's just slain his BFF. Cuchulain and Ferdia were lifelong inseparable friends who, when Ireland went to war with itself, found each other on opposing sides in a battle. Narrative causality meant the inevitable happened...

* Myth/GreekMythology
** ''Literature/TheIliad'': It's Patroclus' death that motivates Achilles to [[AchillesInHisTent get out of his tent]] and kick some [[UsefulNotes/TheTrojanWar Trojan]] ass.
** Also Apollo and Hyacinth, who was an even bigger PrettyBoy than Apollo. Zephyrus was jealous that someone so beautiful was spending all his time with someone other than him, so he made the discus that Apollo had thrown slam into his head and kill him.
* ''Literature/TheSagaOfArrowOdd'': Over the course of his life, Odd loses several of his numerous blood-brothers, each death being a great crisis for him: Asmund, who grew up with Odd, is killed on a raid in Ireland; Thord Prow-Gleam is murdered by Odd's arch-enemy Ogmund, causing Odd to swear vengeance on Ogmund; Hjalmar is killed in single-combat with Angantyr; Gardar is killed at Geirrodsgard when Odd tries to avenge Thord. After the death of Gardar, Odd decides to travel alone, for fear of losing yet more blood-brothers, but ultimately he cannot prevent the death of his last blood-brother Sirnir in battle with Ogmund.
* ''Literature/TheEpicOfGilgamesh'': After the godlike Gilgamesh and his best friend Enkidu spend the first half of the epic wreaking havoc, Enkidu is suddenly stricken down with illness. Gilgamesh, terrified, takes on his next quest -- eternal life -- with gusto as a reaction to Enkidu's death, only to walk away with the story's CentralTheme instead: [[YouCantFightFate everybody dies]].
* In [[FightingIrish Irish]] mythology, 'Literature/TainBoCuailnge'', the tragedy of a war that divided Ireland against itself, the tragic bromance is that of Cu Chullain and Ferdia [[note]]your spelling may vary[[/note]], inseparable friends and closer than brothers who inevitably find themselves on opposing sides in a battle. And fight each other to the death.

* In the Literature/BooksOfSamuel in ''Literature/TheBible'', David and Jonathan. David comes to prominence after he slays the giant Goliath, and immediately, Jonathan becomes one of his most steadfast friends, even defying his father over Saul's command to kill David. But they inevitably must part ways so that David can be kept safe from Saul, even though they meet again a few times over the remainder of the book. Eventually, however, Jonathan, along with his brothers and father, is slain by the Philistine army, causing David to mourn heavily for the loss of his friend and devote all of his efforts into making peace with Saul's family by reaching out to Jonathan's son Mephibosheth. After Jonathan's death, David even laments "Your love to me was [[HoYay more wonderful than the love of women."]]

* ''Theatre/RomeoAndJuliet'': Romeo and Mercutio. The former's murderous rage over the latter's death is what sets the entire final tragedy in motion. See also their equivalents in ''Theatre/WestSideStory'', Tony and Riff.
* ''[[Literature/TheEmigrants Kristina från Duvemåla]]'': Robert and Arvid. Robert's song about Arvid's death, "''[[https://www.youtube.com/watch?v=poMvu9EcyfI Gold Can Turn To Sand]]''", is probably the saddest song in a musical that's filled to the brim with sad songs. Especially poignant in the original Swedish where Robert emphasizes Arvid's death as the exact moment when gold turned to sand (can be found [[https://www.youtube.com/watch?v=jzsUxUhBCtE about twenty seconds into this video]] with English subtitles that aren't entirely accurate (for instance mistranslating the last line as "oh Kristina", and not "and, Kristina"), but close enough that you get the idea).
* Female version in ''Theatre/{{Wicked}}'' with Elphaba and Glinda. Although Elphaba doesn't actually die, Glinda thinks she's dead in the end, and it's implied that thanks to having known, learned from and lost her, Glinda will finally become the good, wise leader that the people of Oz believe she is. "Who can say if I've been changed for the better/but because I knew you, I have been changed for good."

[[folder:Video Games]]
* In ''Videogame/{{Yakuza}} 3'', Rikiya's death deeply affects Kazuma, to the point he breaks his [[TheStoic usually unflappable demeanor]] and [[ManlyTears breaks down crying]].
* ''VideoGame/FinalFantasyVII'': Cloud and Zack. [[note]] It's elaborated in ''LastOrderFinalFantasyVII'' OVA, the ''AdventChildren'' movie and '''specially''' in ''CrisisCore'', where Zack [[HeroOfAnotherStory is the protagonist]].[[/note]] [[spoiler: They met in SOLDIER, became best friends, were part of the horrifying tragedy in Cloud's DoomedHometown, were captured and experimented on, and after Zack managed to escape he took a comatose and traumatised Cloud with him. Zack died at the end of ''Crisis Core'', right as Cloud wakes up from the coma, and his actions '''deeply''' mark Cloud for the rest of his life.]]
%%* ''VideoGame/{{Persona 3}}'': Shinjiro's [[WHAMEpisode death]], from Akihiko's point of view. It's an allusion to Castor and Pollux (see Mythology).
* Solid Snake and Gray Fox in ''VideoGame/MetalGear2'', but [[{{Revision}} properly explored]] in ''VideoGame/MetalGearSolid'', where it's shown Fox's death has broken Snake's heart when Fox [[CameBackWrong Comes Back Wrong]] as a cyborg [[StalkerWithACrush desperate to fight Snake to the death so he can find some peace]].
* ''Franchise/FireEmblem''
** In ''[[VideoGame/FireEmblemJugdral Fire Emblem: Genealogy of the Holy War]]'', Sigurd and Eltshan were best friends since their teen days, they remain close as adults, they trust each other like almost no one else... but then they're pit against each other, [[spoiler: and Eltshan is ultimately executed.]]
** ''VideoGame/FireEmblemAwakening'' has Chrom and [[CanonName Robin]], if Robin is male or a female not romancing Chrom. [[spoiler:Chrom's tragic murder at Robin's (possessed) hands leads to TheEndOfTheWorldAsWeKnowIt and the BadFuture Lucina and the other children hail from.]]
** Done in almost the exact same fashion in the backstory of ''VideoGame/FireEmblemFates'', between [[spoiler:Anankos and the unnamed Vallite king, who were best friends like their kids, [[CanonName Corrin]] and Azura, would be in the future. An increasingly unstable Anankos, in a fit of rage, accidentally murdered Azura's father, which was the final straw in his already-unstable mind snapping completely and him becoming the BigBad. Even more tragically, the King was an AllLovingHero and apparently tried to comfort Anankos as he died.]]
%%* ''VideoGame/TheLegendOfDragoon'': Dart and Lavitz
* In ''Franchise/MassEffect'' [[TheLancer Garrus]] seems to take [[TheLeader Shepard's]] death this way, especially if you influenced him to be more Renegade in the first game. Following the destruction of the Normandy, he heads back to the Citadel, either to rejoin C-Sec or try to become a Spectre. Either way, after seeing the Council bury evidence of the Reapers and [[IgnoredExpert discredit everything Shepard did]] he decides he's finally had enough of the Citadel's bureaucracy and heads to the galaxy's WretchedHive to try and fight crime at its source. This is especially sad if you take him back to Omega after you've recruited him and he notes that despite everything he did, he never actually make a difference.
* In ''KnightsOfTheOldRepublic'', Revan and Malak were best friends before their fall the dark-side, leading Malak to eventually betray his oldest friend. When confronted with an amnesiac Revan who has returned to the light-side, he only regrets betraying them from afar and mourns the loss of the "[[ARealManIsAKiller real]]" Revan.
* ''VideoGame/DynastyWarriors'': Liu Bei took the deaths of his sworn brothers, Guan Yu and Zhang Fei, very hard that it drove him into a RoaringRampageOfRevenge to destroy Wu for their betrayal. If you really think about it, the deaths of Guan Yu and Zhang Fei not only caused Liu Bei to abandon his ideals and go on a revenge spree instead but it marked the beginning of Shu’s downfall when Liu Bei was unable to avenge their deaths and died, leaving the kingdom in his son’s hands who ended up surrendering Shu to Sima Zhao in the later years. As seen in Shu’s hypothetical route in ''DW 8'', if the player followed Xu Shu’s strategy in Fan Castle, Guan Yu wouldn’t have died, Zhang Fei wouldn’t have been betrayed by his own men and Liu Bei would still continue his mission for a land of benevolence and defeat Cao Cao in the end.

[[folder:Visual Novels]]
* ''VisualNovel/{{Danganronpa}}'' features an {{Odd Friendship}} between [[ClassRepresentative hall monitor]] Kiyotaka Ishimaru and [[JapaneseDelinquents biker gang leader]] Mondo Oowada. They have a fierce rivalry at first and only [[FireForgedFriends become friends]] a few days before Mondo is [[SympatheticMurderer pegged as the murderer]] for the second trial. After Oowada's execution, Ishimaru falls far into a [[DespairEventHorizon despair-induced]] HeroicBSOD and never recovers.
** [[PassionateSportsGirl Aoi Asahina]] and [[HugeSchoolgirl Sakura Ogami]] could count as a gender-flipped version, too, as they become incredibly close friends almost immediately and Sakura's [[DrivenToSuicide suicide]] turns Asahina into something of a WoobieDestroyerOfWorlds, though she gets better.

[[folder:Western Animation]]
* ''WesternAnimation/AvatarTheLastAirbender'': Fire Lord Sozin and Avatar Roku. It's a twisted version since Sozin intentionally left Roku to die, although he regrets doing so by the time of his death.

[[folder:Real Life]]
* UsefulNotes/AlexanderTheGreat and Hephaestion, who actually compared themselves to Achilles and Patroclus on more than one occasion, even laying wreaths on their respective graves at Troy.
* Creator/AlfredLordTennyson's ''In Memoriam'' dealt with his emotions surrounding the death of his best friend Arthur Henry Hallam, who died suddenly of cerebral hemorrhaging at the age of 22 (and was, in fact, [[BestFriendsInLaw engaged to Tennyson's sister Emilia]]).
* Either this or StarCrossedLovers took place between UsefulNotes/FrederickTheGreat and [[http://en.wikipedia.org/wiki/Hans_Hermann_von_Katte Lieutenant Hans Hermann von Katte]]. They were friends for many years despite the age difference, Katte tried to help Frederick escape from Prussia to the UK, and when they were caught Katte was executed in front of Frederick...