[[quoteright:350:[[TabletopGame/DungeonsAndDragons http://static.tvtropes.org/pmwiki/pub/images/mm35_pg181.png]]]]

->''"My garden's full of pretty men, who couldn't stay away..."''
--> -- '''Music/HeatherDale''', ''Medusa''

Originally a character in Myth/ClassicalMythology, Medusa has taken a life of her own, and now exists in all kinds of fantasy sometimes as a person, [[AKindOfOne sometimes as an entire species]]. Medusa's main characteristics are snakes for hair and that people [[TakenForGranite turn to stone]] just by [[DeadlyGaze seeing her face]]. So [[TheFourthWallWillNotProtectYou don't look at that illustration]].

In almost all versions, Medusa is fully humanoid and AlwaysFemale. In some versions, her hair-snakes are venomous. In others, they are not literal snakes but rather hair that supernaturally behaves as if it were made of living snakes. When a version contain a male Medusa, it's usually some [[DistaffCounterpart Spear Counterpart]] with some other name. Medusa's appearance varies depending on what source you're reading. The most popular is that of a hideous monster; in fact, the petrification originally was caused by Medusa's ugliness itself, before other myths retconned it into being a power based in her eyes. Other myths say that Medusa retained her mortal beauty, as a cruel {{Irony}}. And then there are some that offer a compromise and state that she was both beautiful ''and'' terrible at the same time.

The oldest story known to feature Medusa is the adventures of Perseus. In this story she is a boss monster whom Perseus defeats by decapitating her (and later using her head to petrify enemies) without looking at her he sticks to looking at her shadow or looking through a mirrored shield, depending on the version.

Myths and stories with background for Medusa were added later. There are two different such prequel myths regarding the origins of the original Medusa. When Medusa is used in fiction as a unique being rather than as a species, she is typically given either one of these two origins, or no origin at all.

The ancient Greek origin is that she and her fellow Gorgons were simply created/born that way. In this origin, the Gorgons are typically three sisters, the other two being Stheno and Euryale. The Greek word "gorgon" means "horror". Besides having serpents for hair, the Gorgons were described as having tusks, brazen claws, wings and strongly acidic blood; in a few very early depictions they are shown as quadrupeds, possibly because {{Pegasus}} was born out of Medusa's blood when she was beheaded by Perseus. Note that the Erinnyes (Furiae) were depicted very similarly as hideous snake-haired women.

The other origin is that Medusa was a virgin priestess of Athena, but her incredibly beauty attracted the attentions of the god Poseidon. Reciprocating, she (with a little help from her sisters) let Poseidon into Athena's temple and slept with him on the altar. Athena, understandably pissed that her priestess not only broke her vows but did the nasty in her temple, punished her by turning her into her new hideous form. She was then banished to a desolate island until Perseus slew her.

Medusa's popularity is somewhat NewerThanTheyThink. She doesn't appear that often in media made before the 80s. ''Film/ClashOfTheTitans1981'' (mentioned below) featured her as one of the monsters - and it has been said that modern generations owe their knowledge of Medusa to the film.

Medusa is the trope namer to GorgeousGorgon. Some of her depictions make her one of the SnakePeople.


[[folder:Anime And Manga]]
* Medusa from ''Manga/SoulEater'' is a witch with a pronounced snake theme (including having magical snakes stored in her body and a snake-like "vector arrow" attack). Even though she still looks "human" she still [[AnimalMotifs strongly resembles a snake]].
* ''Manga/RosarioToVampire'' has Hitomi Ishigami, a MadArtist who turns unsuspecting people to stone for her private collection. Her snake hair bites people and the venom slowly petrifies them.
* ''Manga/SaintSeiya'': The Silver Saints of Perseus, Algol, has a cloth which includes a shield featuring the head of Madusa (just like in mythology). It can turn people into stone when they look into its eyes. Shiryu tried to defeat Algol with the mirror trick it was believed to have been used against the original Medusa but the Silver Saint, [[ItOnlyWorksOnce already knowing how she was defeated]], didn't fall for it. Shiryu had to [[EyeScream pierce his own eyes]].
* A later book in the ''LightNovel/{{Bakemonogatari}}'' series is titled "Nadeko Medusa," which focuses on [[ExactlyWhatItSaysOnTheTin Nadeko imbibing the remnants of a snake oddity and transforming into a Snake Goddess]], complete with snakes for hair.
* ''LightNovel/KagerouDaze'': Azami, an immortal being as old as the planet whose long black hair grows as snakes. She can petrify people with eye-contact, but she controls when/if that happens. [[spoiler:She also happens to be the source of the cast's eye powers and creator of the Heat Haze world]]. She and her descendants (daughter Shion and granddaughter Mary) are called 'medusae' as a species, and regarded as monsters. Shion and Mary also inherited her abilities, but they get weaker as the medusa-blood is diluted (Shion is a HalfHumanHybrid, hence her daughter is only 1/4 medusa) - by Mary's generation, the most she can do is freeze people in place for a few minutes at a time and make her hair wiggle like snakes when highly emotional.
* ''Manga/OnePiece'': [[WorldsMostBeautifulWoman Boa Hancock]] and her two sisters earned the title "Gorgon Sisters" after they allegedly slew a Gorgon, who left them with eyes on their back that will petrify anyone who sees them. Hancock has the ability to intentionally petrify anyone who feels lust toward her, while her sisters can transform into snakes, with one of them being able to transform her hair into snakes. In reality, their powers come from [[GreenRocks Devil Fruits]], and the story about the eyes on their backs is intended to hide their [[spoiler:slave marks]].
* Medusa is the main villain in ''Manga/{{Pygmalio}}''. The protagonist Kurt goes on a journey to defeat her after finding out his mother Galatea was turned to stone along with an entire village. Medusa here is described as the greatest of all demons, second only to the GodOfEvil, and has an entire army of demons serving her. In addition to the standard snake hair and petrifyint gaze, she's also gigantic in size. Anyone who drinks her black blood will become a demon himself.
* One of the first major villains faced by the heroes of ''Anime/{{Shinzo}}'' is Gyasa, a reptile Enterran with snake hair and the complexion and demeanor of the Joker. He turned Yakumo to stone before dropping her off in an acid lake (it's later reversed) and could shed his skin to avoid getting killed, growing stronger each time.

[[folder:Comic Books]]
* ''ComicStrip/TheFarSide'' cartoon captioned "Medusa Starts Her Day" featuring one of his dowdy, bespectacled women showering, wearing a shower-cap through which a snake has poked its head.
** Another cartoon has Medusa growing up (her snake hair becoming GirlishPigtails, braids, beehive...).
* The Franchise/MarvelUniverse used to feature a supervillain/superhero named [[http://marvel.wikia.com/Medusalith_Amaquelin_(Earth-616) Medusa.]] Her superpower was [[PrehensileHair long hair that could be used as tentacles to grab people]]. She was in the Comicbook/FantasticFour for a while. She was eventually PutOnABus to go and live in space with her fellow [[ComicBook/TheInhumans Inhumans]], and mostly appears in Marvel Cosmic books these days.
* ''Franchise/MastersOfTheUniverse'' featured a male medusa-like character with snakes popping out of his eyes rather than hair. The main power, turning people to stone, was the same.
* During the (first) Creator/GregRucka run, Franchise/WonderWoman fought "Medousa", who has the requisite stone-gaze, ''plus'' the claws and wings, ''[[ComboPlatterPowers plus]]'' a CompellingVoice to force people to look at her. [[spoiler:Diana protected herself by [[EyeScream using a piece of the snake-mane to squirt venom into her own eyes]], and then decapitated Medousa.]]
** Several runs earlier, Diana faced a much-less intelligent (but only slightly less deadly) Medusa during a tournament to choose a new Wonder Woman. Petrification from ''this'' one [[NoOntologicalInertia ended as soon as it died]].
* In issue four of ''Comicbook/TheAvengers'' which featured the Silver Age return of ComicBook/CaptainAmerica, Cap encounters an alien who turned the other Avengers to stone with a special ray. The alien had been stranded on Earth for thousands of years living in a cave and Cap surmised that the alien's wild hair, made him look like a woman in the shadows and was the basis for the myth about Medusa. Cap got the alien to change the Avengers back and helped him leave Earth and return home. The alien would turn out to belong to the D'Bari, whose planet was later destroyed when the [[ComicBook/TheDarkPhoenixSaga Dark Phoenix]] caused their sun to go nova.

[[folder:Fan Works]]
* ''Fanfic/PowersOfInvisibility'' has Madusa, an akuma modeled on Medusa, who turns people to stone via EyeBeams.

* ''Film/ClashOfTheTitans1981'' included Medusa as an obstacle for Perseus to overcome - cutting off her head so he can use it to petrify the sea monster who will eat Andromeda. She's made even more monstrous than usual - with a rattlesnake tail that she uses to [[HellIsThatNoise scare people when she's off screen]]. She also becomes an AdaptationalBadass who is pretty nifty with a bow and arrow, hunting down Perseus's comrades one by one. As noted above, this portrayal [[ColbertBump brought Medusa into to pop culture]].
* ''Film/ClashOfTheTitans2010'' includes Medusa's backstory about being cursed. This time it was Aphrodite rather than Athena[[note]]A deleted subplot would have had Athena and Apollo conspiring to help Perseus behind the other gods' backs; presumably having Athena be the one who cursed her would have put her in DesignatedHero territory.[[/note]] - and this version also follows the compromise of Medusa being beautiful and terrible. She's a GorgeousGorgon here, but has a GameFace whenever she petrifies people. She also becomes far more sadistic - cackling cruelly whenever she petrifies someone.
* Medusa is one of the exhibits in ''Film/SevenFacesOfDrLao'', played by Tony Randall. (The film is based on the novel ''Literature/TheCircusOfDoctorLao''.)
* The Film/HammerHorror film ''Film/TheGorgon'', where a small village is terrorized by the eponymous beast and its secret is the DrivingQuestion. In this case, the titular Gorgon is a lot like a werewolf, who transforms at night and is human during the day. It was notably made before Medusa's pop culture popularity - as the Gorgon in this version is named as Magaera ([[SadlyMythtaken who was one of the Furies]]).
* In the first ''Film/PercyJacksonAndTheOlympians'' film, she's played by Creator/UmaThurman. So, not so much hideous. When she discovers that Percy is the son of Poseidon, she snarks "[[FromACertainPointOfView I used to date your daddy."]]

* In Dante's ''[[Literature/TheDivineComedy Inferno]]'', Dante and his guide Virgil are initially barred from entering Lower Hell at the Gate of Dis in Circle Six. Those at the gate threaten to bring out Medusa to turn Dante to stone; Virgil, not trusting Dante to keep his own eyes closed, covers Dante's eyes with his own hands while they wait for divine aid to come to let them pass through.
* Medusa is one of the exhibits in ''Literature/TheCircusOfDoctorLao''.
* Creator/PiersAnthony's ''Literature/{{Xanth}}'' book ''The Source of Magic'' has a Gorgon with snakes for hair. Any man who looks at her face is turned to stone. She is treated sympathetically since she does not want to do this and is forced to live alone; later she marries the Good Magician Humphrey after he fixes her problem by turning her face invisible.
* Creator/ThomasLigotti has a short story called "The Medusa" about an AuthorAvatar who [[GodIsEvil worships the titular character.]] [[TemptingFate Guess what happens.]]
* A gorgon joins the City Watch of Ankh-Morpork in the {{Literature/Discworld}} book ''Discworld/UnseenAcademicals''. She wears sunglasses to avoid turning people to stone when she shouldn't. (In an earlier book, Vimes is very pissed off about citizens interfering with his job by [[FantasticRacism demanding certain kinds of people not be let into the Watch]] and he says that at this point he'd hire a gorgon. [[BrickJoke Guess what]].)
** Previous throwaway mentions: A cross-eyed gorgon with a stone nose was mentioned by one of the monster hunters in ''Discworld/GuardsGuards''. According to ''Discworld/SoulMusic'' Medusa didn't just have snakes on her head: "Underarm hair is even more embarrassing when it keeps biting the deodorant bottle". (The ''Discworld Quizbook'' by Creator/DavidLangford [[{{Squick}} advises against]] [[VaginaDentata extrapolating further]].)
* Medusa is the AlphaBitch for Athena in the children book series, "Goddess Girls".
* Percy faces Medusa (or [[spoiler: Aunty Em, as she's called]]) as one of the monsters he battles in ''Literature/PercyJacksonAndTheOlympians''.
** Later in Literature/TheHeroesOfOlympus. Percy meets the two other Gorgons, Stheno and Euryale. They can't freeze people though, they're also a little touchy about it so don't bring it up. Apparently they had faded away but were restored by a demigod [[ClapYourHandsIfYouBelieve googling their names]].
** Percy also confronts the forgotten other son Chrysaor, embittered at being ignored in legend, who honors his heritage as a son of her and Poseidon by becoming a fearsome pirate. He wears a golden mask modeled after her face and trounced Percy in combat, [[WakeUpCallBoss hard]].

[[folder:Live Action TV]]
* In ''Series/LandOfTheLost'' episode "Meddie," a version of Medusa, appears as a beautiful young woman at first, before her hideous true form is revealed.
* ''Series/RobotWars'' once had a robot called Medusa 2000; the design spec called for a flail at the back, to look rather like snake hair. Unfortunately, the weapon idea fell through, so all that was left was the name and the picture on the top of the robot, which never was shown clearly on TV.
* In ''Series/StarTrekTheOriginalSeries,'' there is a race known as the Medusans. Their appearance is a madness-inducing BrownNote for most humanoid races. They're not bad guys.
* In one episode of ''Series/SwampThing'', Swampy and Dr. Arcane both encounter Medusa in the form of a beautiful woman - that is, she's only beautiful as long as she keeps her sunglasses on. When she takes them off we see glowing eyes and part of a monstrous face. She can't petrify Swamp Thing, as he isn't made of flesh, but she can (somehow) turn him into dry bark. Arcane is a scientist to the core about the whole thing; in one scene she partially petrifies him, and he spends the entire time clinically describing the sensation of his soft tissues being turned to stone.
* One of the later ''Series/LegendsOfTheHiddenTemple'' rooms was Medusa's Lair, where contestants had to properly place snakes into Medusa's head.
* The ''Series/TalesFromTheDarkside'' episode "Miss May Dusa" involves an amnesiac woman discovering that she is Medusa.
* Medusa appears as a character in ''Series/{{Atlantis}}'', where she is initially a normal young woman with whom Hercules falls in love after the heroes rescue her from the cult of the Maenads.
* Medusa is the MonsterOfTheWeek in an episode of ''Series/BigWolfOnCampus''. She looks like a regular human, and can turn people or objects to stone by making eye contact. Merton falls victim to her.
* Medusa is present in the Enchanted Forest in ''Series/OnceUponATime''. It turns out that her head can't be cut off, but she also ''isn't'' immune to her own gaze. Petrifying herself also seems to restore her other victims back to life.

* The song "[[https://youtube.com/watch?v=c4WCK8P-LHg Medusa]]" by folk artist Music/HeatherDale (which provides the page quote) describes a Medusa who has chosen to own her identity as a monster in the face of other people's scorn.

* Since this is a trope about a mythological creature, see the trope description above for the most common versions of the mythology.
* Medusa was a Libyan goddess who was equated with Athena before the Greeks defeated them and [[{{Demonization}} demonized her]] as Athena's enemy and inferior.
* Another origin is that Medusa and her sisters were so beautiful that they angered Athena by bragging about being more beautiful than the goddess, in any case, Athena turned them into monsters so hideous men would turn to stone if they looked at them. A slightly different version of this origin is that they were ''still'' beautiful, but they couldn't be looked at without the beholder turning to stone, making their beauty pointless.
* A slightly different version of the second origin is that Medusa was willingly seduced by Poseidon rather than raped. In some versions, we'll never know if it was consensual. The ancient Greeks (and a number of modern cultures) define rape as having sex with a woman against the wishes of her patron - either her husband, her father, or in this case, Athena. The woman's decision is entirely inconsequential.

[[folder:Professional Wrestling]]
* Wrestling/{{CMLL}} has had at least two wrestlers with this [[TheGimmick gimmick]], one in the late 1980s and another in the 2000s. Despite neither being very prominent, [[HumiliatingWager their wager matches]] got more than a few people's attention, [[RuleOfSymbolism for obvious reasons.]][[/folder]]

[[folder:Tabletop Games]]
* In ''TabletopGame/DungeonsAndDragons'' Medusas have always been a species, but they have undergone some changes between editions.
** In 2nd edition, Medusas are a race that resemble elven maidens with serpents for hair and the ability to petrify with their gaze, even affecting creatures on the Ethereal or Astral Planes (which they can see into). Approximately 10% of the females are "Greater Medusae", who have super-toxic blood and [[SnakePeople a giant snake's body in lieu of humanoid legs]]. There are also male Medusae, called Maedar, who appear as [[BizarreSexualDimorphism bald muscular elven men]]. Maedar are ridiculously rare; whereas female Medusae produce 2-6 Medusa daughters by [[InterspeciesRomance mating with human men]], the result of a Medusa/Maedar coupling is 2-6 offspring, with 25% being male and the remaining 75% being female. Only ''1%'' of the males are Maedar; the rest of them, and ''all'' of the females, are pure human. In addition to lacking the hair-snakes, Maedar have no petrifying gaze; instead, they are immune to petrification, paralyzation and Medusa venom, can walk through stone, and can undo petrification with a touch.
** In editions 3 and 3.5, Medusae are an AlwaysFemale species with a humanoid body but serpentine skin. See page illustration. Petrifying Gaze attack as well as poison bites from the hair snakes come with the package. It is mentioned that Medusae can procreate with any humanoid species, the offspring normally becomes Medusae. There is no official cure for the petrification, but advanced magic can do the job.
*** In Savage Species, several intelligent monsters including Medusas were made into playable classes: If you wanted to play a Medusa under the standard rules you had to start at level 10 or higher, but with Savage Species you could start as a level 1 immature Medusa who had not yet developed her full potential. The same expansions also introduced a Feat that allowed Medusas to enable and disable their gaze attack at will or to focus it at specific opponents, allowing others to see their faces without being turned to stone unless the Medusa wants to do so. Sadly, like most monsters in the book, Medusas are CoolButInefficient due to not only losing so many class levels to normal player character races, but also because their two main powers (petrification and poison) are things that are extremely dangerous to normal PC races but something that [[UselessUsefulSpell many monsters are immune or highly resistant to]].
** In fourth edition, Medusae are a species in the usual sense, with both males and females. The female are the classic medusa, pretty much the same as in the previous edition except that she can now un-petrify her victims by applying a drop of her own blood. The males have different powers, in that they're bald (so no snake-hair attacks) and they can poison with their gaze rather than petrify, rather like certain mythological depictions of the basilisk. Having male medusas with different powers has been done by the game before, as stated above, but this is the first time the concept made it into a core book. Both sexes resemble the scaly humanoid from 3rd edition, though with less haggish features.
** In the fifth addition, Medusae look like humans with snakes for hair, have males with identical powers and are cursed to turn into Medusae on an individual basis.
* In the ''Dungeons and Dragons'' setting "TabletopGame/ScarredLands", the Medusae species was created by the titan Mormo. In this setting, pretty much everything was created by the Titans, including the Gods. Two centuries ago, the Gods rose up against them in what came to be known as the Titanswar or The Divine War. The Medusae was initially an important force at the titan's side, but they switched side to serve the Gods particularly the neutral evil goddess Belsameth.
* In the ''Dungeons and Dragons'' setting ''{{TabletopGame/Eberron}}'', Medusae have a unique culture largely based around avoiding looking someone in the eyes--they're not immune to the petrifying gaze of other medusae, so its kind of the only choice. They were created by the [[EldritchAbomination daelkyr]], but broke free when the [[SealedEvilInACan creatures were sealed away]]. Oh, and there are explicitly males as well--where do you think all the baby medusae come from?
* MagicTheGathering has its fair share of Gorgons. Most of them have some variety of Deathtouch, which will destroy any creature that gets close to them. One that deserves particular mention is the [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=253728 Xathrid Gorgon]] which is the only one to actually [[TakenForGranite petrify]] its enemies.
* In ''{{TabletopGame/Pathfinder}}'', Medusas are rather tragic, as they are not innately evil, but rather are driven to pursue their dark desires out of spite, scornful of those who shun them for their curse. They can mate with any race capable of reproduction with humans, although their children are always female and always bear their curse. They also have literal hearts of stone that are constantly petrifying and un-petrifying themselves, and the places they live [[WalkingWasteland tend to be blighted]] because their petrifying gaze indiscriminately wipes out the local wildlife (including pollinators such as birds and insects).
** The 6th Bestiary introduces the Euryale, an epically powerful Medusa variant supposedly representing ancient Medusa {{sages}} corrupted by [[OneBadMother Lamashtu]]. They have the lower body of a giant serpent, with stony plate-like scales and are ''enormously'' more powerful -- Challenge Rating 20, which is just behind things on the level of DemonLordsAndArchDevils! As well as the spellcasting abilities of 18th level Oracles, they have a wide array of extra abilities. For starters, not only can they turn the petrified corpses of their victims into [[AnimateInanimateObject animated statue defenders]], but if those corpses [[LiterallyShatteredLives shatter]], they can "consume some of the victim's essence" and [[VampiricHealing restore health by doing so]]. Perhaps not coincidentally, they also have several powerful [[MakeMeWannaShout sonic attacks]], in the form of spell-like abilities for Greater Shout, sonic analogues of Fireball, and even the "kills you if you hear it" Wail of the Banshee spell, and a special trait that makes it easier for them to shatter petrified creatures with their sonic attacks. Their venom and their serpents are much nastier than those of their little sisters, and they can turn any blunt weapon they wield into a Rod of the Viper -- an enchanted item consisting of a [[LivingWeapon live and angry serpent]] they can use to simultaneously beat someone to death and bite repeatedly with venomous fangs. Oh, except their version can also spit fangs like poisoned darts.

[[folder:Video Games]]
* ''VideoGame/KingsQuestIIIToHeirIsHuman'' features a Medusa antagonist in the desert. The hero needs a mirror to defeat her. He also needs to face away from her, or else he's petrified instantly. If he has the mirror and the player types "use mirror" fast enough, the Medusa will see herself and be turned to stone. If he doesn't have it, or doesn't use it quickly enough, she will catch up and force him to look at her.
** The AGD FanRemake added a new wrinkle. She is in a cave instead of the open desert, and there is more than one way to solve the puzzle - the traditional mirror, or a test of character.
* ''VideoGame/HeroesOfMightAndMagic III'' and ''IV'' had Medusas as minions of the Dungeon faction. ''II'' had them as neutral (recruitable) creatures. Several of the VideoGame/MightAndMagic games also had medusas. ''VII'' even used the same ''sprite'' as Heroes III.
* Medusa heads are a recurring enemy in the ''{{Franchise/Castlevania}}'' games, with the gold variant able to inflict a petrification StatusEffect starting in ''VideoGame/CastlevaniaRondoOfBlood''. Many games of the series have Medusa herself appear as a {{Snake Pe|ople}}rson. Two games have her appear as a gigantic head instead for some reason.
** ''VideoGame/CastlevaniaLordsOfShadow2'', a reboot, also introduces Medusa's sisters Stheno and Euryale. In this game, they are closer in appearance to their original description in Myth/ClassicalMythology, rather than as snake-women.
* Medusa appears as a lower-level boss in ''VideoGame/FinalFantasyIII''.
** She is also a mid-level boss in ''VideoGame/FinalFantasyMysticQuest''.
*** Medusas also appear as mooks in many of the other games; particularly the earlier ones.
* Medusa shows up in the first ''VideoGame/GodOfWar''. Her sister Eurayle was also a boss in the second game.
* In ''VideoGame/CastleCrashers'', Medusa appears as a level boss. Snakes jump from her hair and attack the player, and she has an attack that can turn players to stone. [[spoiler: When she's defeated, Medusa herself is turned to stone.]]
* ''VideoGame/RingsOfMedusa'' does not feature any character with any traits of the mythological Medusa. While "Medusa" is the main villain, she never comes into play herself, and she doesn't have any traits beyond being evil, in a strictly ProtagonistCenteredMorality sense of the word.
* ''TabletopGame/DungeonsAndDragons'' games with medusas as monsters include ''Curse of the Azure Bonds'', ''Gateway to the Savage Frontier'', ''Pool of Radiance'', ''Pools of Darkness'', ''VideoGame/NeverwinterNights'', and ''Secret of the Silver Blades''
* The ''VideoGame/AdventuresOfLolo'' games have a bust of Medusa as an enemy. It paralyzes and kills Lolo if he steps into its line of sight. The only way to get past the busts is to block their line of sight with an egg or Emerald Framer.
* Medusa is a boss in ''VideoGame/NetHack''.
* Medusa, the Goddess of Darkness in opposition to BigGood [[GodOfGood Palutena]], is the BigBad in ''VideoGame/KidIcarus'' and ''VideoGame/KidIcarusUprising''. [[spoiler:Well, at least for the first part of the latter game.]]
* Medusa is one of the Gorgon Sisters that Davey must defeat in one Ancient Greece stage of the NES game ''VideoGame/DayDreaminDavey''.
* Medusa is the boss form of the Gorgon enemy in ''VideoGame/DesktopDungeons''.
* Since she is part of the toy line, Medusa appears in the LicensedGame of ''VideoGame/MonsterInMyPocket''. She is the boss of the fifth level with four other copies in a DoppelgangerSpin and returns in the BossRush.
* ''VideoGame/DarkWizard'' has the Medusa Head as an item that can be used to petrify enemies. There's also Gorgon's Tails, which are the antidote to petrification.
* ''VideoGame/LeagueOfLegends'' has a champion named Cassiopeia which is a snake-woman very similar to that in ''Film/{{Clash of the Titans|1981}}''. She has snake hair and her ultimate ability is to turn enemies into stone in a cone in front of her. Her name is even tangentially related: Cassiopeia was the mother of the princess that Perseus was out to save.
* ''VideoGame/DefenseOfTheAncients'' features Medusa as one of the Scourge/Dire Heroes you can pick. She's a marksman and for quite some time, her ultimate is just a slowing effect. Eventually, it got reworked it into an actual petrification: face her while the ultimate is active and you will turn to stone.
* In ''VideoGame/AgeOfMythology'', chosing to worship Hera when you advance to the Mythic Age lets you train Medusae at your temple. Yes, Medusae, [[AKindOfOne plural]]. As expected, their special ability lets them turn one enemy unit into stone (except Seige Weapons and Heroes). Their scientific name is ''Gorgon chrysaorus'' (while the genus is obvious, the species derivates from Chrysaor, her son with Poseidon).
** Also, Hades players can get Perseus as a hero in the Mythic age. He carries a Medusa head he similarily uses to petrify enemy units.
* ''VideoGame/FireEmblemTheSacredStones'' depicts Gorgons as SnakePeople with snaky hair. They hatch from eggs and use petrification attacks.
* Medusas are regular enemies in ''VideoGame/{{Miitopia}}'', where they are serpentines ladies with a Mii mouth on their faces and a Mii eye on five snakes of her hair. Of course, one of their attack can petrify Miis.
* Medusa is playable in ''VideoGame/{{Smite}}'' and for once, able to go toe to toe against the ones who caused her misery: Poseidon and ''especially'' Athena. She's not a Goddess, but gets the pass for being one of the more famous monsters in mythology (when they have already included monsters like Scylla or Demigods like Hercules)
* Medusa's are among the creatures you can summon in ''VideoGame/{{Scribblenauts}}''. True to the myth, they can turn other characters to stone. You can also summon only a Medusa's head, which Maxwell himself can use to petrify others.
* ''VideoGame/DragonsCrown'' has Medusa as the boss for Route B of the Ancient Temple Ruins. Here, she has the lower body of a snake, scaly green skin, and monstrous clawed hands in addition to the traditional snakes for hair. In addition to her petrifying gaze, she could also summon snakes and shoot EyeBeams. Completing the Request to defeat her solo reveals her history. [[spoiler:Combining both of the classical Medusa origin stories, this Medusa is the youngest of the three Gorgon sisters who desecrated the resident Athena {{Expy}}'s temple by meeting with men there, whereupon [[DisproportionateRetribution she was turned into a monster as punishment]]. She then hid herself away with her sisters, who stayed with her out of pity, until she started showing up again at the temple]].
* A non-hostile Medusa appears in ''VideoGame/PlanescapeTorment'' as one of the women in the [[PlatonicProstitution Brothel for the Slaking of Intellectual Lusts]]. You never clearly see her as she's hiding in a dark room to avoid harming anyone with her petrifying gaze due to having lost the veil she normally wears over her face. Finding it for her is one of the quests you can complete inside the Brothel.
* ''VideoGame/HolyUmbrella'' has a villainess named Donderadusa, who, aside from magically [[TakenForGranite turning people into stone]], looks and acts much more like a stereotypical CatGirl than a classical Gorgon.

[[folder:Visual Novels]]
* ''VisualNovel/FateStayNight'' features the actual Medusa (or, more precisely, her Heroic Spirit, i.e. superpowered ghost) as the Servant [[spoiler:Rider]]. While her eyes still turn people into stone, her "snake hair" is explained to be a negative exaggeration of her [[RapunzelHair really long and luxurious hair]]...however, it turns out it would be more accurate to call this Medusa as the one ''before'' she became a monster. She also has the ability to summon her son Pegasus as a mount. One summonable version of her in ''VideoGame/FateGrandOrder'' (specifically summoning her as the Gorgon of legend) ''does'' have the snakes for hair and all versions of her can apparently shift to [[SuperPoweredEvilSide the monster she eventually became at the end of her life at the cost of her sanity]], which can only be described as a [[EldritchAbomination giant monster made of snakes that can shoot lasers from its single eye]].
* ''VisualNovel/AstoriaFatesKiss'' also features the actual Medusa. She is a Gorgon in the middle of a mob war with her sisters, and is a romance option. She has red hair and can turn people to stone with her red hair. However, she hates how people think of her in mythology.

* One of the girls in ''Webcomic/EerieCuties'' has snakes for hair, but is actually a Melusine.
* ''Webcomic/TheOrderOfTheStick'' has been known to throw in Medusas in the background, so far without ever being part of the plot. There is one standing in line for the ladies' bathroom in the first dungeon the [=PCs=] explore.
** One of the bonus strips in the Dragon Magazine book depicts Durkon meeting a medusa who is being employed by a dwarf to create cheap building materials. Not that there are many job openings for medusas:
-->'''Melissa:''' I can't even practice my hobbies in peace! I spend two months carving a dog statue, and PETA is all over me.
* One of the current plot arcs in ''Webcomic/IrregularWebcomic'' concerns Medusa.
* ''Webcomic/TheWotch'' has Scott, who perennially is petrified (and turned into the opposite sex). On one occasion, this happened when his girlfriend was temporarily changed into a Medusa and looked at him, after ''he'd'' been turned into a female elf. They both got better.
** Naturally, it happens ''just'' after he says, after getting turned into a female elf, [[TemptingFate that at least he can still move this time]].
* One of the ''Webcomic/{{Oglaf}}'' strips featured a man who survived a Medusa encounter by being distracted her breasts. In the end it is implied that he got more than a RagingStiffie...
* Turns [[Webcomic/TheNonAdventuresOfWonderella Wonderella]] to stone in one strip -- but she's a CardCarryingVillain at worst, can be nullified by the simple expedient of wearing sunglasses, and quite apologetically explains that the power to turn people into stone isn't under her control.
* She is the main character of ''Webcomic/OlympusInstitute''.
* The title character from ''Webcomic/ModestMedusa'' is a harmless medusa child.
* While Medusa herself has not appeared in ''Webcomic/WapsiSquare'', her sister Euryale has, and she gives an amusing re-interpretation of the legend. Medusa's form was always that way; it was not a curse or anything, and the petrification was under conscious control. The deal with Poseidon in Athena's temple was consensual, and Athena put a price on Medusa's head as a result. Then, Medusa fell in love with this Perseus guy, so they conspired to fake her death at his hands and lived the rest of their lives selling statues.
* ''Webcomic/TheStoryOfAnima'' [[http://tapastic.com/episode/43378 has a little girl in a straight jacket with gigantic snakes for hair appropriately named Medusa, or "Medi", for short]].
* [[CuteMonsterGirl Marina]] in ''Webcomic/MonsterPop'' has snakes for hair and needs to wear sunglasses so she doesn't petrify anyone. This doesn't stop her from being completely {{Adorkable}}, though.


[[folder: Western Animation ]]
* Played with in ''WesternAnimation/ThePowerpuffGirls''. The show had Sedusa; a character with tentacle-like hair (wasn't snakes but definitely had a life of its own) whose speciality was to, [[MeaningfulName yes]], [[InstantSeduction seduce men]].
* ''WesternAnimation/CelebrityDeathmatch'' has Steve Irwin fighting against a Medusa. The fight ends with a ShoutOut to the ending of the original ''Film/{{Clash of the Titans|1981}}''.
* The episode of ''WesternAnimation/TheFairlyOddParents'' where Timmy, Cosmo, and Wanda visit ancient Greece and go to a party at Mt. Olympus features Medusa as a party-crasher.
* In ''Disney/{{Hercules}}'', Medusa was TheWoobie, who makes a [[DealWithTheDevil deal with Hades]] to make herself look like a regular girl.
* Medusa appears in ''[[WesternAnimation/JusticeLeague Justice League Unlimited]]'' thanks to Franchise/WonderWoman connecting the Greek pantheon to this show. Franchise/{{Batman}} and ComicBook/{{Zatanna}} have to be blindfolded in order to meet her - and she sounds like she was raised in New York.
* All three gorgons appear in ''WesternAnimation/AmericanDragonJakeLong''. Aside from their snake hair, they generally look human, and are both good-looking and vain. In addition to their petrifying gaze (which they must intentionally activate), they're also adept at mind control.
* ''WesternAnimation/{{Hurricanes}}'': [[CorruptCorporateExecutive Stavros]] [[BigBad Garkos]] uses the name "Medusa" for some of his business ventures, named his [[OpposingSportsTeam soccer team]] "Garkos Gorgons" and his big sister once dressed herself as Medusa to trick people into thinking players from a rival team were turned into stone.
* The Gorgon sisters in ''WesternAnimation/TheSmurfs'' episode "The Smurf Odyssey".
* One of the students at ''WesternAnimation/GravedaleHigh'', called Dusa for short.
* ''WesternAnimation/SuperFriends'': In "Battle of the Gods", Wonder Woman is challenged by Zeus to steal Medusa's necklace. She eventually defeats her by showing Medusa her reflection with her bracelets, which turns her to stone and restores the Wonder Twins who had been petrified.
* ''WesternAnimation/JonnyQuestTheRealAdventures'': In "Heroes", Jeremiah Surd makes his Quest World avatar turn into Medusa. In addition to the stone gaze, the snakes could detach and their venom could partially petrify. He manages to petrify Race and Jessie, and his snakes petrify Jonny's hand and foot. Jonny defeats him by making his see his own reflection, which turns him to stone and restores the others.

[[folder:Real Life]]
* One development stage of jellyfish is named after Medusa, and jellyfishes are called Medusa in several languages.