->'''Jabba:''' You weak minded fool! He's using an old Jedi mind trick.\\
'''Luke:''' You will bring Captain Solo and the Wookiee to me.\\
'''Jabba:''' *laughs* Your mind powers will not work on me, boy.
-->-- ''Franchise/StarWars'' Episode VI: ''Film/ReturnOfTheJedi''

Some baddies aren't particularly dangerous, but they are [[GoddamnedBats annoying to deal with]], because the usual tricks used by our heroes [[KryptoniteProofSuit don't work on them]]. This kind of opponent proves difficult to be overcome by a hero who is used to fighting using a [[WhenAllYouHaveIsAHammer small repertoire of techniques]]. As such, these encounters force our heroes to think outside of the box. Mostly because it's [[RuleOfCool cooler]] than showing them win fights the same way all of the time.

Common reasons for this include:
* AntiMagic: So much for magic.
* BallsOfSteel: {{Groin Attack}}s won't work on me, lady.
* ContractualBossImmunity: Being a boss immunises you against certain moves.
* GiantMook: Size protects you from being BlownAcrossTheRoom.
* HeavilyArmoredMook: Armor Is NOT Useless.
* ImmuneToBullets: GunsAreWorthless against them.
* TheSpiny: No GoombaStomp for you!
* ShieldBearingMook: LuckilyMyShieldWillProtectMe from a certain angle!

Runs on the same principle as KryptoniteIsEverywhere, as an attempt to avert BoringInvincibleHero. May be part of an ElementalRockPaperScissors system. BackStab, CriticalHit and OneHitKill are popular abilities to be immunised against. PunchPunchPunchUhOh is a common consequence. Subtrope of NoSell, supertrope to InvincibleMinorMinion which is this UpToEleven. BreakMeter and InjuredVulnerability is where you can break the Kung Fu Proofing by harming them enough (or zeroing in on the AchillesHeel you find).


[[folder:{{Anime}} and {{Manga}}]]
* The Anti-Magic Field Drones in the [[Anime/MagicalGirlLyricalNanohaStrikerS third season]] of ''Franchise/LyricalNanoha'' ... which just means you have to use MoreDakka or MagicKnight tactics.
** Although, once the {{Power Limiter}}s are removed, the [=AMFs=] really don't stop Nanoha and Fate from bringing down the whoop-ass on Jail Scagletti, Quattro, [[spoiler:and Sankt Kaiser-mode Vivio]].
** Eclipse shown in ''Force'' is a much better example, since it seems to make those who have it {{Nigh Invulnerab|ility}}le to magic.
* In the first ''Manga/RanmaOneHalf'' movie, our hero encounters a ''giant'' (and I do mean '''giant''') man. All that fat makes him feel no pain from kicks or punches.
* ''Manga/FistOfTheNorthStar'':
** Mr. Heart is an enemy [[{{Kevlard}} so fat that only Nanto Seiken can injure him]], hence why Shin sicked him on Kenshiro. Kenshiro countered this by ''moving'' the fat away [[CrazyPrepared with a move created to do just that]], [[DidntSeeThatComing leaving Shin speechless]].
** [[BigBad Souther]] is apparently immune to Hokuto Shinken, at least until Kenshiro discovers his pressure points are inverted due a rare [[http://en.wikipedia.org/wiki/Dextrocardia cardiovascular condition]].
** Parodied with Dù Tiān-Fēng from the spin-off ''Manga/FistOfTheBlueSky''. Knowing that Liú Zōng-Wǔ (an Hokuto Ryuu Ken practitioner) is after his head, he decided to defend himself from his pressure point attacks by procuring a [[ExactlyWhatItSaysOnTheTin Pressure Point Defense Suit]], that not only defends his pressure points but electrocutes anyone trying to hit them. When he finally found him on a ship, Liú Zōng-Wǔ [[CuttingTheKnot simply kicked him in the ocean with his rubber-soled boots]].
* A number of Stands in ''Manga/JojosBizarreAdventure'' can't be beaten through conventional means, like Justice, which is a Stand made of air and thus intangible, and Yellow Temperance, a Stand made of flesh-eating goo that can't be destroyed (and obviously even ''touching'' it is a bad idea.) Both Stands are beaten by [[spoiler: breathing in the Stand to suffocate the [[{{Synchronization}} synchronized Stand User]], and just attacking the Stand User directly, respectively.]]
* In ''Manga/DragonBall'' Goku faced a monster name Buyon who was a giant purplish-pink creature. No matter what Goku did he couldn't hurt Buyon since his blabber absorbed all of his attacks and even deflected the Kamehameha. Solution, Goku kicked in a wall and let the cold air freeze Buyon (he was in a winter area), making him so firm that Goku shattered him in one kick.
* In ''Manga/OnePiece'' Hordy minions tried to defeat Sanji ( [[ExtremityExtremist who has kick-based fighting style]] ), by sending mooks, wearing coats covered in huge spikes. Turns out, that [[DoubleJump he can walk on air]].
* ''Manga/TigerMask'':
** Black V, Wrestling/BoboBrazil's fictional apprentice, was trained to have circus contorsionism-level of flexibility to be immune to submission holds, and he shows it on-page when he takes the Fujiyama Tiger Breaker (a devastating submission move) and [[NoSell just shrugs it off]]. He's then [[OhCrap horrified]] when Tiger Mask [[SubvertedTrope shows him the Fujiyama Tiger Breaker can still work on him if used in a certain way]].
** Kintaro Oki, Bobo Brazil and Black V are almost immune to attacks on their heads thanks to [[UseYourHead their heavy use of headbutts increasing the already great hardness of their heads]]. They're not ''completely'' immune, as hitting those heads with enough strength or something harder ''will'' have effect, but pulling it off is extremely hard.

* Good luck countering something with split second in ''TabletopGame/MagicTheGathering''; you can't respond to it. Or something [[ExactlyWhatItSaysOnTheTin uncounterable]], for that matter. Once in play, we have several other options, including:
** Indestructible. This does not stop zero-toughness and other state-based effects.
** Protection from X. Whatever X is, they can't be damaged, enchanted, equipped, blocked, or targeted by it, leading to the abbreviation DEBT. There are still ways to destroy them, like with [[TheEndOfTheWorldAsWeKnowIt global spells]]. Even then, you can simply change its type from (say) land creature to land to avoid this. Or return it to your hand with another spell.
** Unblockable. As long as this creature's attacking, your creatures can't block it.
* There are many examples in [[TabletopGame/YuGiOh Yu-Gi-Oh]], but perhaps the most extreme is Vennominaga the Deity of Poisonous Snakes, which is immune to all spell, trap, and monster effects. The only way to beat it is to kill it with a stronger monster (which is often difficult, as it gains ATK points based on monsters in the graveyard, and can reach very high numbers), or by exploiting a loophole and tributing it with the cards Lava Golem or Volcanic Queen. Of course, it's pretty difficult to summon this card in the first place.

* Yellow enemies for the old ComicBook/GreenLantern.
** Or enemies armed with wooden weapons (e.g. Sportsmaster with his bats and hockey sticks) for the ''original'' Green Lantern.
* Various ComicBook/XMen, for various reasons, are, or have been {{retcon}}ned to be, immune to telepathy due to government experiments (ComicBook/{{Wolverine}}), messed up heads with way too much going on in them (Wolverine, Rogue), powers (ComicBook/{{Magneto}} in some continuities), equipment (Magneto again, TheJuggernaut). Others are specifically immune to each others' powers, usually in the case of siblings like the Summers brothers or the Frost sisters.
** Because telepathy can stop most fights before they start, either being conveniently immune or knocking the telepath out before the fights starts are frequent strategies, especially when you have a solo villain.
** You also have villains like the Blob, the Juggernaut, or Sinister who are immune to everything. This requires either clever, out-of-the-box thinking, or a DeusExMachina, depending on the writing quality.
** Syndicate in the Ultimate continuity is immune to telepathy. Which is convenient, since Professor X has to deal with him solo.
* One of the first enemies [[ComicBook/FantasticFour the Human Torch]] ever fought was the Asbestos Man, a guy with a suit and net made out of, well, asbestos.
* Minor MarvelComics villain the Metal Master has the psychic power to control any metal, but he suffers a VillainousBSOD if he comes to believe his powers are failing him. TheIncredibleHulk (during one of his early "smart" incarnations) tricked him with a huge wooden gun painted to look like metal; while the villain panicked, the Hulk finally got close enough to grab him. Metal Master suffered an even bigger emotional breakdown when he realized ComicBook/RomSpaceknight's armor was made of an alien metal he ''legitimately'' couldn't control.
* One JusticeLeagueOfAmerica story established that ComicBook/PlasticMan is immune to most telepathic attacks because he doesn't have a physical, organic brain; his whole body is just made of the same [[VoluntaryShapeShifting amorphous stuff.]] He discovers this when he has to fight a BrainwashedAndCrazy ComicBook/MartianManhunter, who has psychically defeated everyone else.
* One of the most deadly things about ComicBook/{{Venom}} as an enemy of ComicBook/SpiderMan is that, as a result of all the time it spent bonded with him (as part of its origin in the series), it doesn't activate Spidey's SpiderSense when it approaches. Spidey usually relies on this ability when dealing with pretty much anyone else, so, whenever Venom is his enemy, he generally has to try other tactics (most often around exploiting its weakness to sonic vibrations and loud sounds).

* ''Franchise/StarWars'' has several examples of characters immune to the Jedi "mind trick" of Force Persuasion, to avoid letting the Jedi have too easy a time of it:
** Watto in ''Film/ThePhantomMenace'' and Jabba the Hutt in ''Film/ReturnOfTheJedi''.
** Given that Force Persuasion only works on the "weak-minded" as Obi-Wan puts it, foiling it doesn't require any special immunity. Knowing what it is (and when a Jedi is attempting it) seems to help. Indeed, Han seems to be at least somewhat resistant to mind tricks in ''Legends'' (as shown in the short story ''[[Literature/NewJediOrder Recovery]]''); it helps that his brother-in-law Luke is a Jedi.
** In ''Franchise/StarWarsLegends'', the [[Literature/NewJediOrder Yuuzhan Vong]] are transparent to the Force, apart from Force Lightning and indirect applications of the Force, like hurling a boulder at them with telekinesis.
** Also in ''Star Wars'', the Droidekas have shields that make them immune to both lightsabers and their own blaster bolts reflected from lightsabers. [[SubvertedTrope The clone troopers are equipped with blasters strong enough to punch through their shields]].
* The MadeOfIron LondonGangster from ''Film/NinjaAssassin'' is surprisingly ninjitsu-proof compared to everyone else in the story.
* Used in ''Film/ThreeHundred''. Under normal conditions the Spartans should just use the "force everybody off the cliff" strategy that they first utilized. This is indeed what the Greek forces did in RealLife. So in the movie, Xerxes ups the ante with war rhinos, crazy berserkers, and Immortal warriors [[NotEvenHuman without faces]] to keep them from doing it again.
* Inverted in ''WesternAnimation/KungFuPanda'': [[spoiler: Po, the hero, is revealed to be immune to villain Tai Lung's TouchOfDeath powers purely due to being so fat]].
* In ''Film/PacificRim'' the Kaiju Otachi {{No Sell}}s Crimson Typhoon's famed Thundercloud Formation attack by catching all three of it's arms.
* In ''Film/XMenDaysOfFuturePast'', the Prototype Sentinels are designed with non-metallic alloys to keep Magneto from affecting them, [[spoiler:which he gets around by weaving metal into them while they're being transported to D.C.]]

* In Creator/LarryNiven's ''Literature/KnownSpace'' setting, the thrint conquered the galaxy by using telepathy to enslave everyone. Then they [[TooDumbToLive didn't watch their slaves closely]] and some of them engineered immunity to telepathy. The telepathy-immunes started a revolt. Then the thrint [[TakingYouWithMe killed themselves and every slave in the galaxy]], leaving the rebels to (mostly) starve to death.

* ''Franchise/StarTrek'':
** Ferengi are telepath-proof.
** One ''Franchise/StarTrek'' novel features a character who is "esper-blind." They are utterly incapable of sending or receiving any telepathic signal. This turns out to be very useful in solving the problem of the week.
** The Doctor from ''Series/StarTrekVoyager'' is a hologram, and as such is immune to physical attacks, unless they are aimed at his holographic emitters or holoemitter.
* In the ''Series/DoctorWho'' serial ''The Time Monster'', the Master tries his usual trick of hypnosis -- "You will obey me. You--will--obey--ME!" -- on the 500-year-old king of Atlantis, who laughs and says that he's much too old (and learned in the sacred mysteries) for that to work on him.
** There are also various beings on whom the Psychic Paper is ineffective, including particularly clever humans such as William Shakespeare, or anyone with the right training such as Torchwood employees.

* ''TabletopGame/DungeonsAndDragons'':
** In most incarnations, elves are immune to ''sleep'' spells. Bummer.
** In both 3rd editions, a staggering variety of other creature types are immune to one thing or another -- critical hits, flanking, mind-affecting effects, energy drain, magic in general, non-magical weapons, or more commonly several categories at once. Listing all the creature types and immunities takes up multiple pages of the rulebook.
** Golems in particular have magic resistance as their major schtick. In earlier editions (1st/2nd and Pathfinder) they are entirely immune to magic, with extremely limited and specific exceptions. If the party cannot fool a golem or sneak past it, physical brute force is the only option. (Though the 3rd and 3.5 editions try to stick with the same theme, the immunity is significantly narrowed in scope, and rules loopholes mean that golems are particularly ''weak'' to certain kinds of spells.)
** This is the bane of the Rogue class -- their main advantage in combat is that when they flank an opponent or catch them unaware, they can sneak attack them for extra damage. Unfortunately for them, anything that's immune to critical hits is also immune to sneak attacks, so they effectively lose their main trick against undead, elementals, oozes, golems and a whole host of other monster types.
** TabletopGame/{{Pathfinder}}, as an adaptation of 3.5, continues the tradition but does remove some of these immunities when they conflict with the RuleOfFun. So Rogues can sneak attack many more targets, but monsters often retain resistances and immunities.
** Editions before 3rd often have a slew of monster resistances and immunities. The absolute king may be TabletopGame/{{Planescape}}. Most of the major parts of the settings are dimensions populated by immortal angels, demons, organic robots, djinn, fae avatars, and so on. Each of these races often have a slew of immunities along with Magic Resistance (a percentage chance to ignore a spell regardless of the caster's level, before saves). They frequently have complete immunity to weapons which are not magical or made of special materials. Additionally, weapons are weakened when "far from home," so your magical weapon might be so depowered it cannot harm your enemy at all. A medium-level enemy (a lesser demon) might possess: Immune to non-magical fire, poison, cold, electricity. Half damage: Magical Fire. +2 or Cold Iron weapon to hit. Magic Resistance: 30%. There just isn't much left to throw at them.
** This trope in ''D&D'' frequently is a modest nod to a creature's mythical origin or even a GeniusBonus. For example, Minotaurs are immune to Maze spells. Elven sleep resistance is almost certainly a nod to Tolkien's ''Literature/TheHobbit''. ''TabletopGame/{{Pathfinder}}'''s Jabberwocky is afraid of Vorpal swords, which are the only weapon which bypass its Damage Resistance.
* Blanks from ''TabletopGame/{{Warhammer 40000}}'' continuity are immune to, and nullify, psychic and [[{{Hell}} Warp]] powers.
** Also known as Pariahs, they are soulless psychic voids whose mere presence makes normal humans deeply uncomfortable. The Culexus Assassin school recruits exclusively from these people, resulting in assassins who are effectively invisible as no normal human mind wants to notice them. Specialists in slaying pskyers, for whom the Culexus represent horror. Even ''daemons'' probably find them disturbing -- in fact, the rules for them in ''Inquisitor'' explain that daemons can't even ''see'' them.
** [[http://wh40k.lexicanum.com/wiki/Blank Blanks and Pariahs]] may not be exactly the same thing, necessarily. DependingOnTheWriter, sometimes. Blanks nullify psychic powers in a certain radius around them, the same field causing revulsion and discomfort in normal people, and enormous discomfort in psykers. [[Literature/{{Ravenor}} Sometimes]] they can have their blankness negated to allow psychics to operate near them. Pariahs additionally lack any presence in the Warp, and can become Culexus assassins, using this fact to power their anti-psychic weaponry.
* Prevalent in TabletopGame/TheWorldOfDarkness. For example, in Old ''TabletopGame/MageTheAscension'', the principle antagonist, the Technocratic Union, deploy many deadly MechaMooks or Men In Black with anti-magic abilities. Older vampires tend to be able to shrug off mind control and other powers by their lessers. Hunters as player characters turn this on their enemies, with their Conviction providing a host of immunities to the powers the monsters used to maintain TheMasquerade. Further examples abound.
* The monsters section of ''TabletopGame/WitchGirlsAdventures'' is littered with monsters with blanket immunities to things.
** Dragons are immune to Elementalism, Giants (Lesser and Greater) and Zombies are immune to Mentalism, Mummies are immune to Elementalism, Illusions AND Mentalism AND they can create Zombies.
** Horrors are immune to Alteration, Mentalism, Time and Space magic, and you pretty much have to 1-shot them to kill them, since they can teleport out of our reality at will. Which can be pretty hard when hearing them talk reduces all but the strongest-willed into madness.
** Ghosts, Reapers and Wraiths are immune to everything EXCEPT mentalism and necromancy. They also respawn if killed in physical form, and are immune to physical attacks in their intangible form.
** Magivores are the masters of this, being immune 2 to unspecified types of Magic that vary randomly amongst the species, meaning that witches won't even know (even passing lore rolls) what the immunities are. Their Resist Magic is so high that a failure for a spell to work could either be due to immunity or a low Casting roll, and there's no way of knowing. Plus if they hit you, besides the chance of reducing your magic abilities across the board, they're guaranteed to reduce at least one of your magic types, and knowing how [=GMs=] think, that type will be the one that they're vulnerable and exactly what you needed to defeat them. Couple that with how Mundanes can't ever see them, and that they can simply teleport to your side no matter how far away from them you flee, and they are pure terror.
** [[TheWitchHunter Malleus Maleficarum]] soldiers are able to shrug off any magic effects used against them, period, due to their iron implants. This only applies to effects that directly target ''them'', however; destroying their weapons or dropping an anvil on them works just fine.

* This is the schtick of the boss Red Giant from ''VideoGame/FinalFantasyVIII''. He will respond with gloats and snarks each time your attacks have little to no effect on him. Tip: Gravity is his AchillesHeel.
* There are certain {{mooks}} in the Nintendo 64 ''VideoGame/BomberMan'' games who are invulnerable to various elemental-type bombs. The most annoying? Without a doubt, the ones impervious to Fire Bombs -- the basic, and most versatile, bombs.
* ''Franchise/{{Metroid}}'':
** The Power Troopers in ''VideoGame/MetroidPrime'' are the most difficult of the reverse-engineered space pirates for this reason. All your fancy new upgrades won't do squat to them. The Chozo Ghosts are also immune to your stronger weapons. Both are vulnerable to Super Missiles, however.
** In ''VideoGame/MetroidZeroMission'', there are these black space pirates which are only weak to your beam, which are annoying to kill. All the missiles, Super Missiles, Power Bombs, Screw Attack? All completely useless. The two in the escape sequence can give players grief, aside from an AIBreaker.
** [[HilariousInHindsight Amusingly]], a KungFuProofMook in ''VideoGame/SuperMetroid'' is a Space Pirate that uses kung fu-like moves. It is only briefly vulnerable after it jump-kicks.
* ''Franchise/{{Kirby}}'' games:
** Scarfys cannot be inhaled. If Kirby tries to inhale them, they'll go crazy and start to chase him down, but then explode after a few seconds.
** Mumbies and some of the larger enemies in certain games are also impossible to inhale (requiring Kirby to spit something at them or use a [[PowerCopying Copy Ability]]) or at least take much longer to do so, though they don't get mad like Scarfys do. Interestingly, [[AllCavemenWereNeanderthals Dogons]] in ''VideoGame/KirbysDreamLand3'' invert this; they ''can'' be inhaled, but most of the more advanced attacks don't work against them as they [[AttackReflector knock all projectiles back]] at Kirby.
* ''Franchise/SuperMarioBros'':
** [[TheSpiny Spinies]] [[ExactlyWhatItSaysOnTheTin are spiny]], immune to [[GoombaStomp stomping]] and must be killed by fireballs, while Buzzy Beetles are immune to fireballs. ''VideoGame/SuperMarioWorld'' puts them together with the Spike Top (spiny ''and'' fireproof); thankfully, you still have ways around that combination.
** ''VideoGame/PaperMarioTheThousandYearDoor'' has flying Spiky Parabuzzies, who are immune to both your standard attacks; they can't be jumped on because they're spiky, and can't be hammered because they fly. The solution is to either equip the Spike Shield badge (which enables you to jump on them without getting hurt) or use a non-jump attack that hits the air (like Hammer Throw). If you don't have ''either'', then at the point in the game where you first encounter them you'll have the crystal star super attack that deals fixed damage based on performance, and can at least knock their wings off.
** Spiked Paragoombas have the same abilities (wings and a spiked helmet), but appears much earlier in the game. The same goes for Bristles, which are ground-based but have spikes all over. Just getting close to one means you get a poke and your attack fails. Since you most likely have neither Spike Shield or Hammer Throw at this point, it means breaking out the consumable item attacks.
* ''Videogame/DonkeyKongJungleBeat'': the elephant turrets are one of the few enemies in the game Donkey Kong can't simply beat by pounding on. He must use explosives or hijack one a Ninjape is using and then use it to shoot the others.
* The ''Franchise/ShinMegamiTensei'' series lives on this trope. You'll be in a dungeon doing some grinding, and suddenly X enemy comes up. You do check its Hit Points and it's not much, you could ''easily'' rip it a new one. Then you hit him with a physical attack: it does ''one'' hit point of damage. Throw fire magic? Immune. Ice magic? ''[[AttackReflector Bounces back]]''. Electric magic? [[FeedItWithFire It drains and recharges its hit points]]. Argh!
* Shedinja from ''Franchise/{{Pokemon}}'', depending on what kind of Pokémon you have in your team. Shedinja's ability makes it immune to everything that it's not [[ElementalRockPaperScissors weak]] against. It's a Bug/Ghost-type, so it can only be harmed by Fire, Dark, Rock, Ghost, and Flying-type moves. But since it's a OneHitPointWonder and those elements are pretty common it usually ends up being AwesomeButImpractical. It also gets KO'd by any form of indirect damage, such as from weather, status effects, entry hazards like Spikes, or contact damage from Rough Skin/Iron Barbs, which further limits its usefulness. To push it even further, any Pokémon with the Mold Breaker ability can plow through it without need of an attack it's weak against.
** As of ''VideoGame/PokemonXandY'', Shedinja has access to the Safety Goggles, which will keep it from being harmed by weather effects. In a double/triple battle, if you manage to paralyze it, along with giving it the Sturdy ability (Which gives a LastChanceHitPoint to a Pokémon at full HP, except Shedinja is ''always'' considered to be at full HP...) via Entrainment or some other method, this transforms from it a KungFuProofMook to a NighInvulnerable monster that can only beaten via a few very specific methods.
** In [[TournamentPlay competitive play]], Shedinja's viability among the [[CharacterTiers tiers]] is rather interesting. In the Standard tier it tends to drop fast to the frequently-in-play weather effects/status effects/Stealth Rock/[[CrazyPrepared specially prepared moves]], but in the Uber tier, which contains [[OlympusMons the nastiest Pokémon in the game]], such effects are less commonly used and most rely on raw power -- thus, a Shedinja played late in the match (when your opponent's conscious Pokémon, and thus variety of attacks, are limited) can be a nasty surprise.
* In ''VideoGame/{{Iji}}'', Komato Assassins can dodge a lot of weapons, including the [[InfinityMinusOneSword Plasma Cannon]]. They therefore need quite a bit more effort to defeat than most mooks.
** Nukes still work though.
** Asha in particular (who's technically a boss, but still acts like a souped-up assassin) could theoretically dodge every single attack you throw at him (including nukes during the rematch,) but refuses to dodge attacks from your weakest weapon [[HonorBeforeReason because it's beneath him.]]
** The [[BonusBoss hacker Yukabacera]] will also dodge kicks and projectiles, despite [[BossInMooksClothing resembling the second-weakest mooks in the game]].
* The ghosts in ''VideoGame/JadeEmpire'' can't be hit with weapons (but can be punched). [[TacticalRockPaperScissors The reverse applies to Golems, while demons are immune to chi magic styles]].
* In ''VideoGame/PrinceOfPersiaTheSandsOfTime'', enemies can be broadly divided into three categories. Those who die instantly to the vault attack. [[DemonicSpiders Those who put you in a world of hurt every time you try.]] And a single boss who just blocks it. Almost every enemy is vulnerable to the wall kick attack, so in the end no mooks are kung fu-proof; some just require a little more sophisticated kung fu.
* ''VideoGame/BatmanArkhamSeries'':
** In ''VideoGame/BatmanArkhamAsylum'', throughout the game but especially in the challenges, there are the regular mooks, and then there are the mooks with knives, who are block/counter proof and will screw up your combo if you use a basic attack on them without stunning them first. Then there are the mooks with stun batons ...
** ''VideoGame/BatmanArkhamCity'' changes the rules: while stun baton henchmen are still immune to frontal attacks, there's a new dodge/counter move to use against knife-wielding henchmen. It also introduces shields, which make the mooks bearing them invulnerable unless stunned and aerial attacked, and armored henchmen, who are immune to regular strikes (but tailor-made for the new beatdown finish) and silent takedowns (and one Predator Challenge involves clearing a room of nothing but armored henchmen).
* In ''VideoGame/PsiOpsTheMindgateConspiracy'', the EliteMooks are equipped with special armor that makes them immune to your psi powers. If you set them on fire with pyrokinesis, though, they become vulnerable for a split-second before they extinguish themselves.
* The [[EliteMooks Spetznaz Elite]] in {{Singularity}} are equipped with special armor that renders them immune to the age-people-into-dust ability of the TMD. [[GameBreaker Deadlock stasis bubbles]] still work on them, however.
* In the 360 game ''VideoGame/{{Wet}}'' there are two versions, the leaders who can not be hit with a sword,and the sword wielding ones who can not be killed by bullets, unless you stun them.
* In the ''Franchise/AssassinsCreed'' games, some mooks can break free of your grabs or block assassination attempts that aren't done InTheBack.
** The [[PraetorianGuard Papal Guards]] in ''[[VideoGame/AssassinsCreedBrotherhood Brotherhood]]'' can outright block counters (or "counter" you during this -- though you take no damage), unlike in ''2'' where the EliteMooks were still hurt by non-fatal counters, and the Papal Guards are immune to Smoke Bombs deployed in open combat. They however are vulnerable to the kill streak mechanic, which actually makes them tougher by themselves than with a weaker, non-Kung Fu Proof Mook for you to start a kill streak with. The Papal Guards' Ottoman counterparts, the Janissaries, in ''[[VideoGame/AssassinsCreedRevelations Revelations]]'' take this UpToEleven; they can block kill streaks too!
** In ''VideoGame/AssassinsCreedIII'' the simplest way to kill mooks in combat is to block their attack and stab them. This doesn't work on officers though. The higher ranking the officer, the fewer types of attack work on him.
* ''VideoGame/DwarfFortress'' averts AnnoyingArrows, as bolts and arrows are capable of piercing organs to do fatal or debilitating injuries, making them quite a useful weapon. However, certain monsters, like iron men, bronze colossi, [[DemBones skeletal]] anything, and many [[spoiler:[[LegionsOfHell demons]]]] ''don't have organs or blood'' and thus have to be torn apart to be killed, which arrows and bolts are very bad at.\\
This applies to a lesser extent to whips (which are currently [[GameBreaker horrendously overpowered]] for their ability to causes immense pain and enormous injuries through armor), since they also don't feel pain and whips rarely destroy whole limbs, but they're still able to [[GradualGrinder chip them into pieces]].
** Made even worse if you have the misfortune of coming up against a Forgotten Beast that has a "blob" body type of stone or any stronger material. Not only does it not have internal organs to destroy or blood to lose, it doesn't even have limbs you can hack off. It's a clear sign that the RandomNumberGod hates you.
* Pursuit Cops from ''VideoGame/MirrorsEdge'' will dodge away from your usual running attacks and are immune to counters. You're best off avoiding them, but they are vulnerable to disarms from behind. ''ME'' is built around running away, melee combat and stealing guns. Pursuit cops are immune to melee combat 90% of the time, run as fast as you, and have guns. Killing one can easily become a personal [[CrowningMomentOfAwesome CMoA]].
* The [[VideoGame/PlantsVsZombies Screen Door Zombies]] carry [[ExactlyWhatItSaysOnTheTin Screen Doors]] that protect them from most frontal attacks. [[AntiFrustrationFeature Fume Shrooms]] can hurt them, though.
* ''Franchise/StarWarsLegends'':
** In the ''[[VideoGame/DarkForcesSaga Jedi Knight]]'' sequels, humanoids with disruptor rifles go down the same way as anyone else, but the trick is that you can't block their shots with a lightsaber, so you can't just charge straight ahead at them without taking hits, and if the disruptor rifle is charged up enough, it's a OneHitKill. There's also the occasional [[EliteMook Reborn]] in ''VideoGame/JediAcademy'' that can't be affected by Force Push and Pull at all -- because the game doesn't want to give you an opportunity to automatically win so many battles by throwing someone into the abyss they're jumping over to get to you. In other cases, it's clearly intended that you do so, or the opportunity may or may not present itself as the fight goes on.
** ''VideoGame/TheForceUnleashed'' has the Stormtrooper Commanders, which are your average {{mooks}}, except that they have a Force-proof bubble around them. The usual Force Lightning or Force Push don't work, but your lightsaber and hurled debris still does ...
* In ''Franchise/TheElderScrolls'' games, ghosts can't be harmed by weapons unless they're magic, silver or Daedric. Magic also works fine. Fists usually work on ghosts.
* The third and fourth bosses in ''VideoGame/{{Descent}} II'', which are both ThatOneBoss, are impervious to energy weapons, while the fifth is immune to mass weapons, and the FinalBoss can only be damaged on its hard-to-hit backside. The Diamond Claw fires homing plasma balls back when hit with energy weapons.
* In ''VideoGame/DantesInferno'' the Heretical Priests are immune to the cross. This combined with their TeleportSpam would be enough to make them GoddamnedBats, but what makes them all-up DemonicSpiders is their ability to confer that immunity ''on other enemies''.
* The Zuul from ''SwordOfTheStars'' are immune to plagues without needing vaccine research, though they can't use plagues against others either. Spectres can only be hurt by energy weapons. High-end shield techs can outright nullify certain weapon types.
* Ceph Heavies/Devastators and Grunt Commanders from ''VideoGame/{{Crysis}} 2'' are immune to {{Back Stab}}s whereas even [[spoiler: Ceph Guardians]] are not. Grunt Commanders also need to be weakened before Alcatraz can do the OneHitKill NeckLift-and-throw, while Heavies by their large size are understandably completely immune to this.
* Every non-starter enemy in ''VideoGame/GodOfWar'' needs to be softened up before Kratos can grab it.
* ''VideoGame/{{Plok}}'' gives us Shprouts, which become shocked and jump into the air when hit for the first time and need to be hit a second time ''immediately'' afterwards in order to defeat them; taking too long "resets" them, forcing you to start over. It becomes worse when they begin to carry shields in later stages, requiring Plok to hit them in the back by deliberately missing them with a [[FloatingLimbs limb]] he throws at them, [[BoomerangComeback making it hit them on its way back]]; sneaking up behind them won't work well, as they turn around after the first hit.
* ''Franchise/DevilMayCry 3'': Hell Envies are functionally identical to Hell Prides, except that they are almost impossible to launch or knock back.
* In the reboot of ''VideoGame/{{Syndicate}}'' higher-ranking enemies are initially immune to Breaches and must be softened up first. EliteMooks invert this by being immune to damage until Breached. There are also Jammer Commandos who block out Breaching against enemies in their AOE.
* ''VideoGame/ResidentEvil4':
** The later Ganados, with more developed Plagas often don't die immediately when headshot, and need a couple extra shots to kill the parasite. The Type 3 Plagas can separate completely from the host. All are instantly killed with Flash Grenades, though. ** ** ** [[HeavilyArmoredMook Masked Zealots]] are impervious to [[BoomHeadshot headshots]].
** Garradors can only be damaged from behind.
** [[ExactlyWhatItSaysOnTheTin Regenerators]] [[HealingFactor regenerate any damage inflicted on them]] unless you [[AttackItsWeakPoint hit their hidden Plagas]], which you need a thermal scope to see.
* In ''VideoGame/PerfectDarkZero'', some [=dataDyne=] guards wear helmets, which are resistant to head shots.
* ''VideoGame/XCOMEnemyUnknown'': Chryssalids, Cyberdiscs and Sectopods are immune to the Arc Thrower's stun, thus you can't take them alive. These three, along with Berserkers and Ethereals, also have the Hardened property, which drastically reduces the likelihood of a CriticalHit to compensate for the fact that they can't use cover. More often than not, the reduction is big enough that you'll get zero chance to crit.
** Ethereals also have a ''very'' high resistance to psi-attacks such as Mindfray.
* Zombies and skeletons in ''VideoGame/{{Minecraft}}'' are weak to the sunlight, but if they are wearing any kind of helmet, then the sun doesn't do anything to them. You have to kill them yourself.
* ''VideoGame/{{Dishonored}}'' features Overseers, who have frontal armor that can take a few instant-kill crossbow bolts to the face, and Tallboys, who have all-round armor and must be killed to be neutralized. Played with for some of the bosses; they're as weak as mooks, but keep respawning from one-hit kills for a while. [[spoiler:You need to destroy Granny Rags' Cameo to finally kill/K.O. her, and Delilah will appear for real one you've killed enough of her duplicates.]]
* ''VideoGame/TheSecretWorld'' spreads a variety of mooks and minibosses with passive shield effects as the player gets through Egypt and into Transylvania. Some, like vampires, are merely highly resistant to afflictions. Others will simply ignore Impairs. It gets worse as you approach Lairs, Nightmare mode bosses, or missions like The Girl Who Kicked The Vampire's Nest, and enemies will actively benefit from players who use the wrong kung fu : the Besieged Farmlands' lair is filled with enemies that silence player characters that Impair them.
* In ''VideoGame/{{Fallout 3}}'', enemies using [[InvisibilityCloak cloaking devices]], such as the [[McNinja Chinese ninjas]] in ''Operation Anchorage'', cannot be hit (or in ''VideoGame/{{Fallout 4}}'', targeted) with VATS. Radscorpions are resistant to being crippled with the Dart Gun, since it uses their venom for the effect.
** Due to a bug, Cazadores in ''VideoGame/FalloutNewVegas'' can't be targeted in the head with VATS unless it is the first body part locked onto.
* In ''VideoGame/{{Warframe}}'', some enemies outright don't give you the BackStab prompt, and some others -- usually shielded ones -- are durable enough that the BackStab will not OneHitKill them.
* In ''VideoGame/{{Borderlands 2}}'', some enemies are bulletproof, at least in Ultimate Vault Hunter Mode. Worse, regular bullets fired at them will ricochet and, usually, hit ''you''. In order to kill them, you need to either use explosive weapons or E-Tech.
* In the TowerDefense ''VideoGame/DesertMoon'', there are Hunters. These guys will tunnel under the sand, invulnerable to ranged attacks until they get near to a unit and surface, then rush at that unit and kill them. Furthermore, they have ''a lot'' of health. It's a good thing they're [[KillItWithFire vulnerable to the Flamethrower]], which hurts them a lot and even pushes them back.
* The Avatar from ''VideoGame/GhostHacker''. It takes a ''maximum'' of 2 damage from anything, making the slow but strong towers bad against them. However, DeathOfAThousandCuts and [[StandardStatusEffects Memory Leak]] will wear them down quickly.
** The sequel brings us the Graviton, which sucks in any projectile attacks. You need to upgrade your towers into lasers in order to defeat them easily.
* In ''VideoGame/{{Something}}'', Boss Bass is the gimmick within Dat Bass, and to make things worse, it is immune to fireballs.
* Titania Capital in ''VideoGame/OdinSphere'' is infamous for being ThatOneLevel partially for having ''two'' of these: slimes and [[EliteMook purple wizards]]. The former suffers only chip damage from physical attacks and offensive psypher magic, and is ImmuneToFlinching except for the strongest attacks, and the latter teleports away each time he's hit. Technically, the slimes demand that the player kill them with offensive alchemical mixes like Napalm, while the wizards need to be hit with their own projectiles and stunned before moving in for the kill, but every character that goes to Titania (except Cornelius, which is why the stage is hardest for him) has a special move that {{One Hit Kill}}s slimes and deals enough damage to the wizards with one hit that it's easier to just spam that instead.
* ''Franchise/MassEffect'':
** ''VideoGame/MassEffect3'': Cerberus Dragoons and Phantoms, being ninjas, are immune to over-cover insta-kill grab attacks, which work on everyone else. Also, Dragoons and CAT-6 Heavies, since they have an armour bar but no health bar below it, cannot be directly targeted by Overload (although they can be hit by arcs), which is especially sucky since Heavies bunker down behind a massive omni-shield that has to be overloaded to destroy it.
** In ''VideoGame/MassEffect2'', Husks and Abominations gained an Armor value on higher difficulties, making them immune to biotics until it's destroyed -- especially bad because biotics are normally an instant kill and lower difficulties rely on using quick-recharging biotic powers to nullify the large numbers of Husks you encounter.
* In ''VideoGame/AstroBoyTheVideoGame'', [[UndergroundMonkey red enemies]] are immune to [[KnockBack knockdown]].
* ''VideoGame/{{Spelunky}}'' has several:
** [[BigfootSasquatchAndYeti Yetis]] and {{shop|liftAndDie}}keepers are immune to the {{whip|ItGood}}; the remake adds [[HeavilyArmoredMook green knights]] to this list.
** The remake also adds enemies that are immune to unaided {{Goomba Stomp}}s: the aforementioned green knights, giant frogs, and mammoths; mummies have also been promoted to this status. None of the above are immune to spike shoes, however. %% Mantraps and devils are covered on "The Spiny".
* ''VideoGame/SpyroTheDragon1998'' has two varieties. {{Giant Mook}}s can't be [[UseYourHead charged]], and armored ones are immune to Spyro's [[BreathWeapon fire breath]]. So, of course, a couple areas have giant, armored enemies, though there are still ways to deal with them. [[spoiler:The armored giant spiders in the High Caves, for example, can be taken down with a supercharge.]]
* Uruk captains in ''VideoGame/MiddleEarthShadowOfMordor'' are usually immune to several of your attacks or abilities, such as stealth attacks, ranged attacks or being jumped over. To compensate, they have vulnerabilities as well. Berserkers are flat-out immune to all regular attacks and must be stunned or countered before they can be attacked.
* Enforcers in ''VideoGame/WatchDogs'' are immune to takedowns until a certain skill is unlocked.
* In ''VideoGame/HotlineMiami'', Thugs are immune to melee attacks unless you're using Tony, and even when shot with a non-shotgun firearm, can still keep going for a while until they bleed out. The flipside of this is the Charging Prisoner in the sequel, who are immune to guns but get killed just fine by melee attacks.
* Common infected in ''VideoGame/Left4Dead2'' can be killed in a variety of ways, but certain campaigns will have special versions of them that make it harder to dispatch them. Hazmat infected in Dead Center are immune to fire damage, construction infected in Hard Rain are wearing earmuffs so can't hear the attached alarm of pipe bombs, and riot infected in The Parish wear heavy armor that makes them immune to regular weapons fire from the front.

* Black Belt of ''Webcomic/EightBitTheater'' more or less spells this out when White Mage calls him out on his inability to defend himself against giant spiders. He says he was specifically trained to fight humans and humanoids, so his fighting training (for example, attacking pressure points) is useless against the spiders.
* ''Webcomic/KidRadd'' has a few examples where the game physics used by our heroes and the game physics used by their opponents is different enough that problems will ensue. Perhaps the most potent example is the BigBad itself, [[spoiler:the Seer]]. It has absorbed the "any attack just takes away one hit point" trick of the Kid Radd style of platformer; thus no matter [[spoiler:how much Radd charges up]], it'll still be only 1 HP damage. Kind of a bummer after an adventure of overwhelming opponents with [[spoiler:the sheer power granted by his programming glitch]], huh?
** [[spoiler:Radd can charge up to the point where he could utterly destroy The Seer regardless of its programming, but he's not sure how far he should charge up to do so without affecting the rest of the Internet. It's probably a good thing he didn't, though, since The Seer's conflicting death programs caused it to crash upon its defeat]].

* One episode of WesternAnimation/RegularShow involves Mordecai and Rigby fighting a video game character that came to life. When they were playing the game itself, they found the boss was immune to all attacks except for throwing furniture at them. When said boss comes to life, everyone has to trash up the entire house, throwing everything that wasn't nailed down in order to defeat him.
* In ''WesternAnimation/StarWarsTheCloneWars'', Cad Bane shows that even being strong-willed can't help you if the Jedi ''really'' want to persuade you when Mace, Obi-Wan, and Kit Fisto brute-force him into telling them what they need to know. It's clear that being forcefully mind-controlled like that is a horrible deed, Bane's left clearly in mental anguish from it and the Jedi all visibly regret it but have no choice in the matter. That said, for having three Jedi masters persuading him so hard and still managing to not crack until he's nearly knocked unconscious from the mental trauma, it's clear that a single Jedi would never be able to break him.

* In UsefulNotes/WorldWarI, machineguns were a staple of defensive operations. Then along came the tank, a (somewhat) ImmuneToBullets metal monster. Assuming that mechanical failure or rough terrain wasn't in play, the only thing that could really stop a tank was artillery fire, which wasn't always accurate. Needless to say, this real life GameBreaker, along with US intervention, ended the stalemate on the Western Front and helped win the war.
* The perfection of the aircraft carrier as a weapon of naval warfare in UsefulNotes/WorldWarII rendered the battleship obsolete, since it could only lob a shell up to thirty kilometers away at most, while the carrier could launch bombers from hundreds of kilometers away and sink any battleship from a safe distance. This was exemplified by the sinking of the Yamato, the most powerful battleship ever built which was sent on a suicide run against the American pacific fleet towards the end of the war after most of the Japanese carrier fleet had been sunk; it didn't get very far before being bombed and torpedoed to the bottom of the sea without ever even catching sight of the American carriers.
* In the earlier stages of UsefulNotes/WorldWarII, certain tanks were armored so heavily that they could NoSell the anti-tank weapons distributed to infantry at the time, and even in some extreme cases the guns of other tanks! Again, it fell to artillery (and emplacement guns like the Germans' 88mm Flak cannon) to destroy them until technology improved. On the flip side, at the end of the war, Germany produced several tanks and tank destroyers (namely the Elefant, Jagdtiger, and Maus) that were so heavily armored that they were effectively impervious to all the anti-tank cannons being used by the Allies. However, they were so large and slow that they were vulnerable to artillery, tank hunting dive bombers, infantry swarming attacks, and simple mechanical breakdowns.