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->"''When did mankind lose touch with natural selection? No matter how inferior a human's genes are, that person is protected by laws, and can't be killed. Even those incapacitated in accidents or stricken with a serious illness are needlessly kept alive. What a drawn out, wasteful existence. It's this divorce from natural selection that has caused mankind to stop evolving. It's a step down. The devolution of mankind. But I intend to accelerate the culling of genetically inferior humans. To rekindle the refining fire of natural selection!''"
-->-- '''Hans Davis''', ''VideoGame/MetalGearAcid''

Some evil {{mad scientist}}s use their twisted intellect solely for personal gain. This particular villain is not so provincial. His genius and his motives go hand in hand, and his concerns are (he thinks) with the welfare of the human species. Simply put, to the Evilutionary Biologist, humanity is stuck in an evolutionary rut, and it's up to him to put us back on the proper path so we can continue to evolve.

Why the Evilutionary Biologist believes this is necessary varies, as do his methods. Some Evilutionary Biologists simply believe that humanity has erred in its domination of the environment, and thus our very survival as a species is threatened unless they force us to continue evolving. Others see change and so-called improvement as [[ForScience goals in and of themselves,]] and resolve to use scientific advancement to cause them. Still others seek to create a new race of [[BioAugmentation biologically superior]] {{transhuman}}s or just the UltimateLifeForm with the power of science, either because they see humans as having outlived their time on the planet or because of a genuine desire to improve the human condition. They often subscribe to the philosophies of SocialDarwinism and "[[WellIntentionedExtremist The Ends Justify the Means]]". It's not uncommon for them to [[DarwinistDesire practice what they preach]] and marry someone they see as fit and worthy for them.

Regardless, because of his dedication, the Evilutionary Biologist is willing to break laws, engage in [[PlayingWithSyringes experimental alterations upon other human beings]], and ruin lives for [[UtopiaJustifiesTheMeans the higher goal]]. Their creations are no less exempt; whether they're ReplacementGoldfish, with the CloningBlues, or genetically "programmed" to have evil InTheBlood, their "children" are doomed to live sad, short, [[TurnedAgainstTheirMasters rebellious]] lives, unless they really ''do'' feel [[TrulySingleParent parental]]. They will never realize that EvilEvolves, and will never be able to identify themselves as the villains.

Evilutionary Biologists often create [[HalfHumanHybrid inhuman]] [[MixAndMatchCritters monsters]] and {{artificial human}}s to serve as minions and {{Mooks}}, as well as to populate their extensive GardenOfEvil. They themselves may even be willing to [[ProfessorGuineaPig suffer the fruits of their experimentation]], often resulting in [[OneWingedAngel a monstrous, inhuman new body.]]

Whenever an Evilutionary Biologist appears on the scene -- they are the most common form of villainous biologist in many games and SpeculativeFiction media -- be on guard for a ScienceIsBad [[AnAesop aesop]] to rear its ugly head.

This is especially ironic because in real biology, one of the core precepts of the theory of evolution is that it does not "improve" a species, because there is no such thing as an ideal form for a species -- only what is best[[note]]Or rather "good enough". Products of evolution are often TheAllegedCar of the natural world. [[http://en.wikipedia.org/wiki/Argument_from_poor_design#Examples Go figure]].[[/note]] at surviving and reproducing in ''current'' conditions. If the environment changes, the species must adapt all over again, which is why genetic diversity (Nature's way of "hedging her bets") is usually a good thing. Moreover, assuming that a species '''must''' evolve if subjected to imposed selection pressures (or Phlebotinum-induced mutations) overlooks the harsh fact that most organisms ''don't'' adapt in the face of such challenges: they simply go extinct, which is why we're not rubbing elbows with mammoths, sauropods and trilobites today. Deliberately applying such selective forces to humans may let us join them in extinction, not improve upon our current state. Finally, evolution is conservative, and a species which is ''thriving'' (you know, like ''Homo sapiens'') is unlikely to evolve new traits, because it's doing fine the way it is. Sharks, for example, haven't changed much since ''before the first dinosaurs appeared,'' and they're just as successful as ever...making the entire mania of the Evilutionary Biologist suspect at best.

Even so, GoalOrientedEvolution was taken dead seriously by many in the heyday of the Eugenics Movement, and still gets cited by people who really ought to know better [[TheSingularity (Singularitarians]] are frequently guilty of it).

Examples of this trope will probably be [[HerrDoktor German]], and possibly one of ThoseWackyNazis, if we want to be ''really'' [[{{Anvilicious}} obvious.]]

Compare DesignerBabies, UpliftedAnimal, SuperBreedingProgram, and {{Transhumanism}}.


[[folder:Anime & Manga]]
* ''Anime/BlueSubmarineNo6'': EmperorScientist Dr. Zorndyke.
* Chief Kakuzawa's "diclonius" efforts in ''Manga/ElfenLied''. Too bad for him that pissing off the crux of his plans (Lucy) slaps him with the TooDumbToLive label.
* In another Okamodo work, ''Manga/BrynhildrInTheDarkness'', Takachiho, an amateur ''geologist'' who stumbles upon alien corpses and technology while exploring a mine for gold, gets the [[SarcasmMode brilliant idea]] to replace all of humanity with HalfHumanHybrids using the alien's own FantasticNuke to do it and, with a group of like minded individuals, spends 100 years rounding up ''children'' under the age of ten and having "researchers," at gun point, perform horrific experiments indistinguishable from ColdBloodedTorture on them to unlock their "true potential" just to achieve this end. At the start of the story, [[FridgeHorror he's on the cusp of succeeding.]]
* [=DIO=] Brando/Joestar from ''Manga/JoJosBizarreAdventure''. The man works on turning humans into zombies and putting human heads on cats for amusement.
* Okay, so he's a computer scientist, not an evolutionary biologist. But Masami Eiri from ''Anime/SerialExperimentsLain'' could fit this trope nonetheless. He believed that humans had reached the pinnacle of evolution physically, and that in order to continue evolving to more perfect forms, humanity had to give up their bodies for a digital existence. To that end, he [[spoiler:secretly put code into the latest version of the protocol that controls the Wired that would connect humans together on a subconscious level through the network. He also created Lain a physical body to aid in this effort.]]
* [[MadScientist Dr. Ulen Hibiki]] from ''Anime/MobileSuitGundamSEED'', although he hadn't really built his views around evolutionary dead-end, still wanted to advance the human race as much as possible -- ForScience! So, to produce his [[ArtificialHuman Ultimate Coordinator]], he didn't stop before using his own yet unborn (in fact, just conceived) son, [[spoiler:Kira Yamato]], as well as many others, as a guinea pig for his experiments. The fact that he eventually succeeded didn't help him, though, when [[TorchesAndPitchforks he was lynched by an angry mob]].
* ''Manga/AstroBoy'' had a lot of run-ins with guys like this. His own father even became one.
* In ''Anime/BagiTheMonsterOfMightyNature'', another Creator/OsamuTezuka creation, [[spoiler:Ryo's mother was one of these.]]
* The Towa Organization in the ''[[LightNovel/BoogiepopSeries Boogiepop]]'' series see it as their duty to help push humanity forward in its evolution as well as seeking out and destroying the individuals who pose a threat to that goal. Much of the conflict in the series is the direct result of their actions, including the creation of Manticore, a human eating monster cloned from an alien.
** In the novels it seems that Towa wants to keep the "overevolved" individuals in check, and prevent the evolution of humanity in larger scale - ironically they enforce this ideology with Synthetic Humans who have very little difference to the "overevolved" individuals, except that most of them are absolutely loyal to Towa Organization.
* Dr. Jail Scaglietti of ''Anime/MagicalGirlLyricalNanohaStrikers'', the MadScientist behind [[CloningBlues Project F]] and several other ArtificialHuman related experiments. According to [[SmugSnake Quattro]], his ultimate goal is the completion of biomanipulation technology and the creation of a space to do that. That at least several hundred thousand people would die in the process is acceptable collateral damage.
* [[spoiler: [[MagnificentBastard Grace O'Connor]], the resident MadScientist]] from ''Anime/MacrossFrontier''. In Episode 24 [[spoiler: she]] directly stated that [[spoiler:her main goal is for humanity to become greater than [[{{Precursors}} the Protoculture]]]].
* Zeus from ''Manga/KingOfThorn''.
* In ''Manga/{{Naruto}}'', it's Orochimaru's StartOfDarkness: he just wants to learn all the jutsu in the world, and when he realizes he can't in a normal human lifetime, he starts experimenting to put himself above all else. It's more just for his own sake than for the world's, and he's using human guinea pigs left and right.
* Medusa from ''Manga/SoulEater'' would count: experimenting on children with black blood and reviving the kishin, thus allowing his madness to spread, in her mind means the same as allowing evolution to take over. Her older sister Arachne started off a example when she 'borrowed' the work of an {{Anthropomorphic Personification}} and combined witch and human souls to create the first [[EquippableAlly Weapons]]. The effects have lasted centuries, with the Weapon forms even changing over time; there are several gun-type Weapons alongside the older swords or polearms.
* Keith White of ''Manga/ProjectARMS''. He thinks that his pursuit of knowledge leaves him perfectly justified to kill, experiment on, mutate, torture, and otherwise ruin the lives of the human test subjects he works with, most of them children. By the series' end, he has taken to [[AGodAmI declaring himself God]] and insisting that he'll nuke the planet so he can remake it in his image. [[spoiler:The irony is that the sentient alien meteor he was using for this plan, Azreal, only came to Earth because it was drawn to the novelty of human emotions, after spending millions of years alone in space. It helps the protagonists instead, since it doesn't want to be alone.]]
* ''Anime/NeonGenesisEvangelion'': Seele. Next step in evolution apparently is [[spoiler:all of humanity and an EldritchAbomination merging together.]]
* Dr. Genus from ''Webcomic/OnePunchMan'', founder of the "House of Evolution".
* Dr. Akihiro Kanou from ''Manga/TokyoGhoul'', a MadScientist obsessed with the creation of superior HalfHumanHybrids. His ghoulization experiments have an incredibly high mortality rate, with over a 1000 people killed in his efforts to create his hybrids. He claims that he's doing it to free humanity from their cage, but considering that he's [[TheSociopath a Sociopath]] that readily lies to everyone around him, it's difficult to tell how much of this is true. His study at his old laboratory was filled with "hybrids" he'd created by stitching together preserved insect bodies to create things like "Scorpion-Butterflies".
* Aleister Crowley ([[BeethovenWasAnAlienSpy yes, that one]]) of ''LightNovel/ACertainMagicalIndex'' is, in this universe, the founder and leader of [[TwentyMinutesIntoTheFuture Academy City]], a scientifically advanced city located within Tokyo that is comprised mostly of students. Said students are [[ESPer espers]] whose studies are mainly focused on the development of PsychicPowers, which they gain through a combination of drug treatment and hypnosis, and the usefulness of which are ranked from [[PowerLevels Levels]] [[WhatKindOfLamePowerIsHeartAnyway 1]] through [[PersonOfMassDestruction 5]]. Every esper is essentially a human guinea pig in a massive citywide experiment conducted by the scientists that run Academy City, who range from the [[ForScience amoral]] to the downright [[MadScientist insane]] (the Kihara family), and Aleister himself [[spoiler: is a former magician who turned his back on magic after growing disillusioned with a world in which humans allowed their destiny to be controlled by the magical "phases" that can affect a person's fortune. It's implied that his ultimate goal for the espers is to use the unique energy they unconsciously emit, known as [[AppliedPhlebotinum AIM fields]] , to rid the world of magic, which he believes will direct humanity towards its ideal course in which people are freed from fate and mysticism, and the world is built up from the efforts of individuals rather than that of [[RageAgainstTheHeavens the gods]]]].


[[folder:Comic Books]]
* Creator/MarvelComics is filled with these: Mister Sinister, Phaeder, Maelstrom and also possibly ComicBook/{{Apocalypse}}, depending on how strict a definition of biologist is used.
** ComicBook/{{Magneto}} also dabbled into this a bit, with his creation of the Mutates, genetically-altered mutant {{Mooks}} created when the normal-variety mutants just weren't cutting it in his SocialDarwinist army.
** Predating almost all of these is the High Evolutionary (yeah), who can [[FaceHeelRevolvingDoor sometimes]] come across as actually a rather reasonable person. Unfortunately his AGodAmI delusions of grandeur keep driving him to take the theory of evolution and beat it into submission with a sack of rusty doorknobs in order to make his experiments work.
* Marvel's most notable example is probably Miles Warren, aka the Jackal, an enemy of Franchise/SpiderMan. He had a lot of fun cloning Peter Parkers (and Gwen Stacies). Most of the blame for ComicBook/TheCloneSaga was his.
* Dr Payne in the British comic book series ''Comicbook/{{Zenith}}'' created the second generation superhumans with the explicit intent that they replace humanity. [[spoiler:They did. After a fashion.]]
* Bertron, an ancient alien who created the creature Doomsday in ''ComicBook/SupermanDoomsdayHunterPrey''. He was HoistByHisOwnPetard millions of years ago in the days of prehistoric Krypton, but unfortunately for the rest of the universe "The Ultimate" lives on to this day.
* In Franchise/TheDCU, there was the mad obstetrician Dr. Love who created the supervillain team Helix by experimenting on the unborn children of pregnant women under his care.
* According to ''Comicbook/{{Legion Of Super-Heroes}}'', 1000 years from now Ra's Al Ghul will plot to crash the Moon into the Earth to force humanity to [[YouFailBiologyForever pre-emptively evolve]] to prevent it.
* In the ''ComicBook/ChickTracts'', every single believer in evolution is like this. No exceptions.
** Fortunately, they have a KryptoniteFactor in the form of merely hearing that [[NuclearPhysicsGoof gluons have never been seen]].
* Reed Richards [[NotBrainwashed doesn't get infected]] in ''ComicBook/MarvelZombies'', but [[spoiler:infects his entire team with the zombie interdimensional bug]], claiming it's the best course of evolution mankind has been presented with. Being an expendable CrapsackWorld, this is just the beginning...
* [[ComicBook/CaptainMarVell The Supreme Intelligence of the Kree]] has committed monstrous atrocities against his own people in order to spur their evolutionary development.
* Spartacus Hughes in ''ComicBook/TheFilth'', or at least he tries to be. His dabblings in this seem less like a plan to change humanity than just a particular twisted way of amusing himself.
* IDW's [[ComicBook/TheTransformersMegaseries Transformers output]] has Jhiaxus, who among other things introduced gender to Cybertron just because he could (never mind that the person he did this to went insane in the process), and CombiningMecha (which was also insane), not to mention [[spoiler:turning an entire planet into a replica Cybertron. It's implied he did this to more than one planet.]] Just because he wanted to accelerate Cybertronian evolution.
* ''ComicBook/JudgeDredd'': Morton Judd was a genetic engineer who once served as the head of Justice Department's cloning project. He started to see it as the solution to crime by creating a docile population, but Chief Judge Fargo vetoed his proposal on the grounds that it was their duty to police the citizens they have, not create the citizens they'd like. Judd went rogue and fled to the Australian wastes, where for decades he built a CloneArmy to replace the Judges.


[[folder: Fanfiction]]
* In ''Fanfic/ChildOfTheStorm'', [[MadScientist Arnim Zola]] moonlights as this. Worryingly, however, he learned his trade from someone even worse... [[spoiler: Sinister.]]
* In the ''Anime/DragonballZ'' fanfic ''Fanfic/HonorTrip'', [[MadScientist Ratsura]] plays this trope straight as an arrow, [[DepravedBisexual though he himself]] [[AxeCrazy is not straight]] [[JustForPun in the least.]]
* In ''Fanfic/PagesOfHarmony'', Twilight Sparkle definitely counts as this. Using [[ColdBloodedTorture twisted forms of science]], MindRape, and magic to extract the Elements of Harmony from her friends [[spoiler: before killing them]]. She claims that it's all to [[WellIntentionedExtremist preserve harmony]] and set ponykind ([[spoiler: and everything else]]) [[UtopiaJustifiesTheMeans on the right path]].
* In ''FanFic/MegaManRecut'', Otto 'Raptor' Moreau is this.
* In ''Fanfic/WarbandOfTheForsakenSons'', Jikaerus, former Apothecary of the Alpha Legion, is this. In order to create recruits for his master, he released mutated monsters on an world already plunged into eternal night and manipulated entire bloodlines so that natural selection and careful breeding would do his work for him.

* Regressing humans into caveman/werewolf hybrids was the only way for humans to develop further, according to the villain of ''Film/IWasATeenageWerewolf''. Specifically, the scientist says that mankind has become too violent for their own good, a problem which [[InsaneTrollLogic turning humanity into bloodthirsty wolf-creatures]] would surely solve.
* Tyler Durden of ''Film/FightClub'' has the motivation, but not the methodology. He believes society and rampant consumerism are stagnating human development. Rather than combat this with mad science, however, he plans to force humanity to "evolve, and let the chips fall where they may" by crashing the global economy.
* Jigsaw from the ''Franchise/{{Saw}}'' movie franchise is not a scientist, but an engineer, which still fits the trope well: instead of participating in scientific experimentation, he uses the applied science of engineering to build his traps. In a similar variation, his concerns are social rather than biological or genetic - he is disgusted with the indolence and sloth he sees surrounding him. Without the "Will to Live", humankind faces extinction. His preferred solution is to maim and murder people in interesting ways.
* ''Film/TheManWithTwoBrains'': Dr. Michael Hfuhruhurr is in many ways one of these; as well as being not-quite-all-there and his developing God-complex, he confidently predicts a day where his research will allow "brilliant minds to live on in the bodies of dumb people" and the like. He's somewhat lacking in the evil department, though, as for all the MadScientist CharacterDevelopment that occurs, he's a bit too decent and moral to actually kill in order to achieve his ends.
* In the ''Film/JamesBond'' film ''Film/{{Moonraker}},'' Drax's scheme is to wipe out humanity with a human-specific poison pollen plant, then repopulate the Earth with the pairs of perfect supermodels he has kept out of harm's way on his space shuttle/Noah's Ark.
* The Octopus from ''Film/TheSpirit'' is trying to find the secret to immortality and godhood. He actually created the titular hero in one of his experiments when he brought a dead cop back to life. The Octopus' {{Mook}}s are also apparently artificial creations.
* In ''Film/KamenRiderTheFirst'', the organization Shocker's name stands for "Sacred Hegemony Of Cycle Kindred Evolutional Realm."
* The mad scientist in the Japanese/American co-production B-movie ''The Manster''.
* Dr. Mirakle, the villain of ''Film/MurdersInTheRueMorgue''. Although insane, his theory of the descent of man from ape ancestors is impressive, given that the film is set 15 years before UsefulNotes/CharlesDarwin published ''On the Origin of Species''.
* The various film adaptations of Creator/HGWells' ''Film/TheIslandOfDrMoreau'', make Dr. Moreau into one of these. (The original Moreau in the book wasn't trying to improve the species (ours or otherwise), but to refine and explore the limits of his ''unorthodox surgical techniques''.)
* Faora, one of the villains in ''Film/ManOfSteel'', delivers a lengthy speech to Superman about how "evolution always wins".
* The obscure 1956 low-budget film 'The Werewolf' has two of these, who both subvert the one in ''Film/IWasATeenageWerewolf'' and then actually exceed his stupidity. They seize upon an innocent man lost in their remote mountain village and inject him with 'irradiated wolf's blood', causing his transformation. They don't view the werewolf as an evolutionary breakthrough, but as something to be avoided, since they feel this is the fate of a post-apocalyptic humanity, to become ravening beasts once the bombs fall (As always, viewed as inevitable in this era, both in real life and twice over in films). They turn this man into the werewolf so that they can figure out how to let 'geniuses' like themselves survive with their intellects intact. But they like so many others in this trope prove TooDumbToLive while still managing to be the direct cause of a serious DownerEnding. The lead one was particularly JerkAss and really earned his mauling.
* In ''Film/XMenFirstClass'', Sebastian Shaw believes that mutants are further along the evolutionary chain than ordinary humans, therefore they should inherit the earth. And by the end of the film, he's convinced others, perhaps more than he wishes he had:
--> Erik Lensherr: ''If you're in there, I'd like you to know that I agree with every word you said. We are the future. But, unfortunately, [[spoiler: you killed my mother.]]''

* The Operator in ''Literature/{{Duumvirate}}'' has devoted his life to being one of these.
* In ''Literature/OryxAndCrake'', Crake is the consummate Evilutionary Biologist. He designs a new, "perfected" species of human, the Children of Crake, [[spoiler: and decides that humans must be destroyed to make room for them. This plan is [[TheBadGuyWins pretty much entirely successful]]; while the superplague he creates doesn't quite kill ''everyone'', there is [[TheEndOfTheWorldAsWeKnowIt absolutely no hope of human civilization ever coming back]].]]
* Dr. Volescu in Creator/OrsonScottCard's ''Literature/EndersShadow'' series. He genetically engineers superintelligent humans [[spoiler:that have super-short lifespans as a side-effect]].
* Siegmund Loge in George C. Chesbro's ''The Beasts of Valhalla''. He is a Nobelist (often a bad sign in Chesbro's work), famed for his work on a mathematical tool used to predict whether a species is too far along the road to extinction to be saved. In his unpublished, un-peer-reviewed work, he has come to the conclusion that humanity is a doomed species, and must be forced to mutate into MixAndMatchCritters to give it a chance to try again. Experiments on human subjects who didn't volunteer, check. German background, check; bonus, in that he is a fanatical Music/RichardWagner fan. Looks like Santa Claus and has a great public image, and has awesome talents in attracting black budget funding from governments who don't know he's on other people's payrolls or what his agenda is.
* The Meliorare Society in Creator/AlanDeanFoster's ''Literature/HumanxCommonwealth'' series is a group of brilliant scientists and genetic engineers who recklessly violated proscriptions against human eugenics in order to "[[ForScience explore the potential of the human genome]]". They worked by posing as [[TheMasquerade fertility specialists]], among other things, with the plan to reclaim the "superior" children once they started manifesting powers and thereby prove themselves to the galaxy. Instead, several of their more grotesque failures came to light and they were outlawed and hunted down. Those not killed outright were subjected to [[LaserGuidedAmnesia selective mindwipe]], and all of the subjects that could be found were either given mercy killings or "altered" to be as normal as possible. The last few remaining Meliorares went into hiding, carrying their dreams of vindication with them. Flinx, the main protagonist, is one of the subjects who slipped through the cracks, mainly by not manifesting his awesome PsychicPowers until much later in his life, and he has several encounters with Meliorare fugitives who attempt to "reclaim" him. This has not ended well for them.
* Subverted in Creator/RobertAHeinlein's first published novel, ''Literature/BeyondThisHorizon''. The world government genetically engineers everybody for maximum genetic perfection (or, at least, elimination of imperfection), except for a carefully guarded population of "control naturals," and strongly encourages particularly hopeful genetic matches, as between the hero and heroine. The subversion is that this is presented as entirely a good thing. (This society is sometimes described as a "socialist" state but bears more in common with Technocracy. Everybody gets a small annual dividend from the output of the whole global economy as if it were a corporation in which all are stockholders; control naturals get a larger dividend, enough for a livable income, in compensation for their genetic inferiority and inability to compete with the average person.)
* In two separate SF universes created by Creator/FrankHerbert, the planets Dosadi and [[Franchise/{{Dune}} Salusa Secundus]] are both brutally inhospitable prison worlds created to force the beings left on them to adapt and become stronger. The effect seen is more of a cultural (and physical conditioning) change than evolution, though.
** And then, also in Dune, there's the Bene Tleilax which created such things as [[VoluntaryShapeshifting Face Dancers]] that later on in the series can become "perfect mimics" by absorbing the memories of the individual they've... replaced.
* Subverted in Aldous Huxley's ''Literature/BraveNewWorld.'' The World State engineers everyone into five castes, Alpha through Epsilon ranked by intelligence. The point is to keep everything exactly the way it is forever; technological progress is restrained for the same reason. The Savage asks World Controller Mustapha Mond, "If you can get anything you want out of those bottles, why not make everybody an Alpha-double-plus?" Mond says they once tried colonizing an island with nothing but Alphas as an experiment, but it quickly degenerated into civil war; everybody wanted to be boss and nobody wanted to do the scutwork.
** ''Brave New World'' is especially dystopian in that the lower intelligence of the lower castes is not a natural product of genetic variability or even "evolution" in the usual sense. Instead, they've been deliberately handicapped by the introduction of toxins during gestation and development.
* In Creator/CJCherryh's ''Literature/AllianceUnion'' 'verse, Union uses {{Uterine Replicator}}s to produce [[ClonesArePeopleToo Azi]], who are graded by intelligence from Alpha highest down (Rho is mentioned to be the lowest class used as a production-line type). Subverted however, in that the science is handled relatively well, each class consists of multiple genetic types, and the standard practice is to include as much genetic diversity in a population as possible - indeed, one of the purposes of the Azi is to increase the genetic diversity of the space stations they populate. Your Mileage May Vary as to how evil Ariane Emory is, however.
** In a further subversion of the idea in ''Literature/BraveNewWorld'', Alpha Azi are not usually leaders - they take too long to make decisions because they tend to wait for all the information to become available. Betas make better officers.
* Creator/DeanKoontz's portrayal of Dr. Victor Franchise/{{Frankenstein}} in ''[[ExactlyWhatItSaysOnTheTin Dean Koontz's Frankenstein]]''.
* In Creator/CSLewis's ''Literature/SpaceTrilogy'', Professor Weston develops interplanetary travel so humanity and their descendants (whatever they evolve into) could go out into the stars and survive throughout the cosmos. However, Weston doesn't care that this plan may involve wiping out other intelligent life. (In the second book, he abandons this goal in favor of a New Age-y philosophy he dubs "Spiritual Evolution", which has nothing to do with this trope.) The trope is taken further in the third book, where the N.I.C.E. plans to replace all organic life with a machine life.
* ''Literature/TheTurnerDiaries'' by white-supremacist William Luther Pierce (writing as Andrew Macdonald) recounts a racial war that ends with the death of all Jews, nonwhites and "mongrels" -- all of them, everywhere in the world. Most white people also die in the fighting and general disruption; the population of the United States is reduced to 50 million. Only those bearing "especially valuable genes" survive. This fulfills the dream of the "Great One" (Hitler) for an "all-White world." (The historical Hitler would at least have allowed the non-whites to live on as slaves.) The necessity of this appears to be based on "Cosmotheism," a belief-system that is Pierce's own invention, which is a curious mish-mash of the seemingly incompatible beliefs of racism and pantheism.
* The only type of biologist in the employ of [[MegaCorp Manpower Inc]] in Creator/DavidWeber's ''Literature/HonorHarrington'' series. Not only they use genetic engineering to breed [[WeWillUseManualLaborInTheFuture slaves]] for unscrupulous purposes, but they also utilise the experience from this practice to improve ''themselves'', as they feel that natural evolution is too slow.
* An ironic step-sibling of this trope forms the basis for Creator/JohnWyndham's novel ''Literature/TheChrysalids''. In a post-apocalyptic future (the apocalypse is phrased in religious terms by the characters as "The Tribulation", and implied to have been a nuclear disaster or war), a primitive, theocratic society seeks to exterminate all mutants, whether plant, animal or human. While not {{Social Darwinist}}s or scientists, the members of this culture are nevertheless striving to "restore" the purity of life on Earth, in an effort to get back into God's good graces.
* From ''Literature/{{Fingerprints}}'', the doctor who first researched psychic abilities, [[spoiler:Steve Mercer]]. He eventually came to regret his work and tried to undo it, but did ''not'' perform a HeelFaceTurn and remained a WellIntentionedExtremist - just one with different intentions.
* Lord Randolph Hellebore from the ''Literature/YoungBond'' novel ''Literature/SilverFin'' is obsessed with breeding the perfect soldier and is not above experimenting his brother and son in pursuit of his goal.
* Julian May's ''Literature/GalacticMilieu'' books feature Marc Remiliard, whose goal is to accelerate the psychic development of the human race to the same level as [[spoiler:his prochronistic mutant brother Jac a disembodied brain]], he had good PR and merely told everyone he wanted to let people adopt some cool DesignerBabies.
* The Forsaken Aginor in Creator/RobertJordan's ''Literature/TheWheelOfTime'' series. It is revealed that he personally was responsible for the creation of all of the BigBad's monstrous {{Mooks}}, having performed Mengele-esque experiments on his fellow human beings by the thousandfold.
* Dr Peter Whitney is this in the ''GhostWalkers'' series by Christine Feehan. He cruelly experimented on orphan girls inserting animal DNA and altering their psychic abilities. After it went wrong, he tried again with soldiers. Subverted in that Whitney is a genius and has developed many scientific breakthroughs, but he doesn't really worry about ethics or other people.
* 'God' in ''Literature/{{Tarzan}} and the Lion-Man''. He was an English MadScientist who came to Africa to conduct genetic and evolutionary experiments on gorillas. He rejuvenated himself with gorilla genes, but gradually assumed their physical characteristics.
* ''Literature/AMacabreMythOfAMothMan'' has no less than three. Vincent Mordein tried to unlock the secrets of the human brain [[spoiler:and ended up sticking a penny-sized chip in Jack Daw's head, giving him the ability to control crows]]. Dr. Wu performed gene-splicing on multiple subjects, including Ozzy and Moth-man. And Dante Eclipse performed experiments on the cult he heads, believing that humanity is inherently flawed and they must transcend their species to survive.
* In ''Literature/VenissUnderground'', Quin wants to eradicate humanity in order to pave the way for his genetically engineered meerkats to become the new dominant species.
* In the ''Literature/JacobsLadderTrilogy'', the Builders who created ''Jacob's Ladder'' belonged to a religious cult of Evilutionary Biologists who believed that humanity could only advance by facing constant adversity. They expected and indeed hoped for massive amounts of suffering and death among the crew in order to make the survivors stronger.
* Downplayed in ''Literature/ThisImmortal''. George Emmet is not the villain of the piece, but lives purely [[ForScience for science]] and exhibits a LackOfEmpathy, which causes him to do whatever he thinks would improve a species without considering what the moral implications would be. When, at the end of the book, his wife Ellen is pregnant again, he wants to try embryosurgery to create a child capable of breathing underwater... Ellen isn't having any of that, though.
* The Eugenicists in the backstory of ''Literature/StarshipsMage'' started out by quietly manipulating human lineages on Earth to encourage magic in their families. They later took over the Mars colony and began overtly controlling the population and force-breeding test subjects, triggering a war with Earth.
* In Literature/TheVorkosiganSaga the Cetagandan haut caste, especially the haut women; they're basically running a very long-term genetic engineering project to turn themselves into TranshumanAliens.
* The scientists of Chrysalis in ''Literature/StarTrekTheEugenicsWars'' are attempting to make a new breed of humanity to inherit the world.

[[folder:Live-Action TV]]
* Both the Shadows ''and'' the Vorlons in ''Series/BabylonFive'' attempted to force the evolutionary development of the younger races. Disagreement about the best way to go about this eventually led to all out war.
* This is the plan of Adam from the fourth season of ''Series/BuffyTheVampireSlayer'', by combining demon and human parts to create a superior race.
* ''Series/DoctorWho'':
** John Lumic, creator of the "parallel Earth" Cybermen, sees his creations in this way. Davros, in the original series, created the Daleks for much the same reason.
** And the Daleks themselves, who tried to create Dalek/Human hybrids to overcome their weaknesses--only for Dalek Sec to be influenced a little ''too'' much by his new human side. He, naturally, pays the price.
** In the episode ''[[Recap/DoctorWhoS14E4TheFaceOfEvil The Face of Evil]]'', all of the characters are victims of a eugenics experiment being run by Xoanon. By and large, they bear him no hard feelings for it afterwards.
** In AudioPlay/BigFinishDoctorWho [[AbsoluteXenophobe Rassilon]], Founder of Time Lord Society, tried to prevent any races evolving that could threaten the Time Lords. He seeded other worlds to make sure life like the Time Lords would evolve and imprisoned races in other Universes which are in the dungeons of his Foundry.
* [[spoiler:Alpha]] from ''Series/{{Dollhouse}}''.
* ''Series/OrphanBlack'': Dr. Aldous Leekie. His Neolution movement is all about "self-directed evolution" and he sees no problem in creating human clones or experimenting on them to advance this goal.
* In ''Series/KagakuSentaiDynaman,'' the villains' collective name is the Jashinka - from ''jashin'' ψ(`∇´)ψ and ''shinka'' (evolution.) In other words, their name ''actually translates to "Evilution."'' However, their plan to convert humans didn't go so well, so they went the usual mass destruction route.
* ''Series/StarTrekEnterprise'':
** Dr. Soong in was the more benign flavor of Evilutionary Biologist, who balked at his creations' evil tendencies. He later switches to machines, and his descendant in ''Series/StarTrekTheNextGeneration'' ends up being just a really innovative scientist.
** Dr Phlox in "''Dear Doctor''", where he refuses to help the Valakians despite having a cure to the plague that's threatening to wipe out their entire species. Why would the good doctor refuse to help them, you might you ask? Because the Menk, a Neanderthal-like subspecies that lives on the planet, will apparently only reach their [[EvolutionaryLevels evolutionary breakthrough]] once the Valakians are dead. Despite the fact there is absolutely no proof that they will evolve or that the presence of the Valakians is hindering their development in anyway. Particularly baffling, since without the Valakians, the Menk would have died out ''centuries'' ago.
* The Dominion, a major power on ''Series/StarTrekDeepSpaceNine'', established its rule through this trope. Their stormtroopers are bred from birth to fight and made dependent on drugs to keep them docile. Their emissaries are programmed to believe the Founders (the head honchos) are gods. The Dominion isn't above letting loose a super-plague to punish insurgents, either. [[GreyAndBlackMorality Not that the Federation is above it either.]] However, the Federation expressly bans genetic augmentation, which is a major plot point for one of the characters who was illegally genetically modified as a child. While said character ([[spoiler:Dr. Bashir]]) turned out for the better, many of his other cohorts [[WithGreatPowerComesGreatInsanity weren't so lucky.]]
* Helen Cutter in ''Series/{{Primeval}}'' is a different kind of Evilutionary Biologist: in her own words, she wants to [[spoiler: save the world, not humanity. She ends up going back to the Pliocene to kill hominids and prevent the human race from ever evolving.]]
* On ''Series/{{Heroes}}'', Arthur Petrelli wants to make SuperSerum generally available for this reason.
* Michael on ''Series/StargateAtlantis'' eventually becomes one of these, with his plans to create a race of human-Wraith hybrids and wipe everyone else out. His first experiments were possibly the most atrocious, with him forcibly implanting people with Iratus bug eggs so he could find out the effect of different levels of DNA from either species, creating some sort of Xenomorph-esque monsters in the process.
* ''Series/MurdochMysteries'': In "Future Imperfect", Dr. Dryus Alger is a prominent member of the Eugenics Society who is abducting dogs and conducting illegal experiments in his attempts to 'perfect' humanity.

[[folder:Tabletop Games]]
* ''MagicTheGathering'''s DungeonPunk setting of Ravnica has deranged elf sorcerer/scientist [[http://ww2.wizards.com/gatherer/CardDetails.aspx?&id=107506 Momir Vig,]] the leader of the Simic Combine, a whole guild of such characters.
** In the book, there's a footnote that explains that he's [[LastOfHisKind the last of his specific race of elves]], but that he's gone on the record was saying that it's a good thing that they aren't any others left.
** As far as ''Magic'' goes, it was probably inevitable that Green/Blue would be the Biologist guild, since Green is the "Biology" color and Blue is the "Fuck with..." color.
** Then there was Yawgmoth, a firm believer that strength came from conflict. And then he created a biomechanical hell named Phyrexia where CyberneticsEatYourSoul.
*** As of New Phyrexia, three of the five Phyrexian factions are this to varying degrees. Jin-Gitaxias of the Blue faction is one to the greatest extent (the name of his faction, The Progress Engine, is saying something). The leaders of the Green Vicious Swarm, Vorinclex and Glissa, are all about "encouraging" natural selection instead, via extreme predation and survival of the fittest. And the White Machine Orthodoxy wishes to either unite all beings into one ''[[BodyHorror (by stitching them all together!)]]'' or to transform them all into "perfect" soulless dolls. The two factions not concerned with this are the Black Seven Steel Thanes (who are too occupied trying to slit each other's throats over becoming the new [[TheChosenOne Father of Machines]]) and the Red leader of the Quiet Furnace, Urabrask the Hidden, who just wants everybody else to leave him and his servants in peace.
* ''TabletopGame/{{Warhammer 40000}}'':
** [[FanNickname FABULOUS Bile]]... uh, sorry, Fabius Bile. And like most things in that universe, he is this trope turned up to eleven. His master race are superpowered versions of the existing SuperSoldiers, with the difference that they're all homicidal megalomaniacs, and he's turned the population of entire planets into shambling mutants with his experiments. Oh, and did we mention that his labcoat is sewn from human skin? His most ambitious project? [[spoiler:To clone the Emperor.]]
** Tzeentch, the Master of Change. His entire existence is based on evolution, so his followers enjoy having random "gifts" happening at any moment (read: every moment). Which leads into...
** An inversion by Ahriman, who turned the entire Thousand Sons legion (the ones loyal to Tzeentch) into living coffins to STOP the mutations/evolution. Needless to say, he is not well liked, even among the Thousand Sons.
* Dr. Mara Omokage, in ''TabletopGame/{{GURPS}} Bio-Tech'' and ''TabletopGame/TranshumanSpace''.
* ''TabletopGame/{{Rifts}}'' has Dr. Desmond Bradford. He is head of the Lone Star Complex, a Pre-Rifts genetic engineering facility that experimented in intelligent mutant animals. Bradford has created a variety of mutant animal soldiers for the [[TheEmpire Coalition States]], but also secretly performs experiments on humans, attempting to create powerful psychic humans. Note that [[EvenEvilHasStandards even the Coalition]] would pale if they knew what he was up to.
* The whole backstory of Airship Pirates (inspired by ''Music/{{Abney Park}}'') is thanks to a Evilutionary Biologist that confined most of humanity to fortified Victorian cities and let the rest of the world get taken over by nature.
* The ''TabletopGame/TeenageMutantNinjaTurtlesAndOtherStrangeness'' game featured Doctor Feral. A wealthy humanitarian scientist of [[LawfulGood Scrupulous]] alignment, the good Doctor spends his time honestly working toward a better future for all of humanity. His list of medical advances is long, he donates his medical expertise to assist in difficult cases, and even paid to send his maid's children to college. Too bad he only thinks [[WhatMeasureIsANonHuman of human life as being sacred]] and can routinely be found [[TheyWouldCutYouUp vivisecting sentient mutant animals]] in his [[SupervillainLair underground lab]] while he works on that human immortality drug he is pretty sure he is close to finishing. In a game where all the characters are [[PlayerCharacter intelligent mutant animals]] he tends to come off as a less than altruistic person.
* ''TabletopGame/SirenTheDrowning'' features Echidna, leader of the Current of Oceanus, who wishes to improve Humanity through her experiences so they will have more chance to survive the upcoming [[TheEndOfTheWorldAsWeKnowIt Deluge]]. Unfortunately, she is completely insane, and does so by turning any human she gets her hands into monstrous non-sentient FishPeople called Voldianoi.

* The ''VideoGame/BioShock'' series:
** The first game, ''VideoGame/{{BioShock|1}}'', has two example:
*** Yi Suchong, the scientist responsible for the mental conditioning of the Little Sisters and [[spoiler:Jack]] as well as the creation of the Big Daddy.
*** Dr. Bridgette Tenebaum, who made the Little Sisters what they are and is trying to [[TheAtoner atone for her mistakes]] by saving them.
** ''VideoGame/BioShock2'' has [[KnightTemplar Sofia Lamb]]. An insane Altruist, her life experiences [[spoiler: [[CompletelyMissingThePoint and the events of the first game]]]] led her to believe that [[TheEvilsOfFreeWill Free Will is a evolutionarily conditioned illusion]]. In order to release Rapture from the "burden" of self-awareness, she's decided to [[spoiler: ''[[AssimilationPlot fuse all its people into a single, non-aware being using the body of her own daughter]]]]'', believing the result will be a "[[UtopiaJustifiesTheMeans True Utopian]]".
* Palet from ''VideoGame/BreathOfFireIII'' [[spoiler:[[{{Necromantic}} wanted to revive his dead mother]]]], and was very willing to break the laws of nature to do so.
* In ''VideoGame/CommandAndConquerTiberianSun'', Kane's primary plot is to build and launch a world-altering Tiberium missile that will spread Tiberium across the entire planet. He states that this will trigger the next step of humanity's evolution as a species.
* ''VideoGame/DeadSpace'' features two {{Mad Scientist}}s; one relatively helpful and benign despite his insanity, and one who is more clearly villainous. The evil one is an evilutionary biologist, and more than happy to sic his nigh-invulnerable genetically engineered super monster on you.
* The Master from ''VideoGame/{{Fallout 1}}'' was very much an adherent of Evilutionary tenets in the WellIntentionedExtremist mould (certainly, the backdrop of a [[AfterTheEnd post-nuclear apocalypse]] lent his reasoning some gravitas). The Enclave, the adversary of the sequel ''VideoGame/{{Fallout 2}}'', [[spoiler:was in fact a kind of inversion of this trope. being among the last "purebreed humans" in the world, they were planning to commit genocide of all the various mutated strains of humanity that had cropped up, effectively "turning back the clock" on evolution. It is up for discussion whether one of the optional courses of action towards the end of the game, in which the PlayerCharacter convinces one of the scientists responsible for the plan to turn the [[WeaponOfMassDestruction WMD]] they had intended to use for this upon his fellows instead, is a case of using the Evilutionary argument in a more "benign" context]].
** A CrowningMomentOfAwesome for Science characters in ''VideoGame/{{Fallout 1}}'' is when the Vault Dweller, after passing a skill check, [[spoiler:points out that the Master's Super Mutants are entirely sterile and thus doomed to extinction. They're actually ''physically incapable'' of biological evolution.]]
** The ''Old World Blues'' DLC of ''VideoGame/FalloutNewVegas'' has the Think Tanks, with Dr. Borous in particular being responsible for the [[DemonicSpiders Cazadores]] and [[MixAndMatchCritters Nightstalkers]] (which he claims are as [[MetaphoricallyTrue docile as they are sterile]]) as well as subjecting his dog Gabe to some pretty terrible experiments (though it's possible to [[MyGodWhatHaveIDone make him feel regret for the latter]]). They're also responsible for a [[FesteringFungus special spore]] that infects living people and have made lobotomized people into psychotic zombies (or Lobotomites), a process that you barely managed to survive due to the bullet in your head from the beginning of the game.
** Not to mention the fact that ''deathclaws'' and mole rats were developed pre-war as biological weapons against China. Deathclaws were developed for close combat and search-and-destroy missions, while mole rats were developed to be an invasive species. While mole rats are relatively harmless, can be domesticated, and have a genetic kill switch, deathclaws are 9-10 feet tall and live up to their name, and are capable of breeding.
** VideoGame/{{Fallout 4}}: The Institute (basically MIT in post-apocalyptia) generally focuses on creating merciless cyborgs, making breakthroughs in science and technology with no sense of control for the social ramifications, and crushing anyone who could interfere with their work. They're considered the bad guys because even though they mean well and can be highly rational, they've cut themselves off from the Commonwealth and treat its people like toys. This includes testing the FEV on them and loosing any "failures" upon the Commonwealth as the Super Mutants. The head of the project sabotaged the lab because nothing was getting done, yet the CEO kept ordering him to continue with the project and turn the "failures" loose, without so much as even an observational capacity. They don't treat the synths they create any better than they do the people of the Commonwealth either.
* Professor Hojo from ''VideoGame/FinalFantasyVII'' was almost a textbook Evilutionary Biologist, and a thoroughly nasty piece of work.
* He was predated however, by ''VideoGame/FinalFantasyIV'''s Dr Lugae, who was every bit as bad, even if he had less screentime.
* Curien from ''VideoGame/HouseOfTheDead'' is one of these, though [[LoveMakesYouEvil he]] [[JumpingOffTheSlipperySlope wasn't]] [[MadScientist always]]. Goldman has the mentality of one of these, but he isn't a scientist, he's a OmnicidalManiac CorruptCorporateExecutive who dabbles in science.
* ''[[Franchise/MetalGear Les Enfants Terribles]]'', anyone?
* ''VideoGame/MetalGearSolid2'''s infamous GainaxEnding had the Colonel [[spoiler:AI]] justifying the Patriots by referring to this with regards to ''cultural'' evolution, considering the Internet to be what disrupted natural selection. (''VideoGame/MetalGearSolid4'' would reveal that they were probably less than honest about this motivation.)
* The key antagonists of ''VideoGame/ParasiteEve2'' are a shadowy cult who intend to counter humanity's extinction of thousands of species, by 'diversifying' humanity into filling all the ecological niches -- by transforming everybody into hideous and inevitably hostile monsters. Made particularly chilling by the fact that about half of their stated plan -- namely the use of Retroviral Engineering -- isn't too far from being a real possibility.
** [[VideoGame/ParasiteEve The first game]] also had one of these, in the form of Dr. Klamp, who is the one who ultimately created Eve and willingly assists her in her genocidal goals because he wishes to "help humanity evolve".
* Umbrella Corporation from the ''Franchise/ResidentEvil'' games, makers of such fine biological weapons as [[ZombieApocalypse the T-Virus]] and [[ImplacableMan the Nemesis]].
** ''VideoGame/ResidentEvil5'' takes it to a new level with Project W. Ironically this was one of the ''first'' projects Umbrella started in the timeline. Umbrella founder Ozwell Spencer envisioned the rise of a superior breed of humans [[spoiler: consisting of humans infused with the Progenitor Virus at a young age]] indoctrinated with his own SocialDarwinist values and presumably his interest in biological studies. In other words, this was an Evilutionary project ''to manufacture more Evilutionary Biologists''. Fortunately, the project was ultimately a failure since [[spoiler: Albert Wesker and his sister Alex Wesker were the only children to survive the virus injections all the other Wesker children received]].
** Last but not least, there's Wesker's evil plot itself from the same game as above. To put it in his own words, "Natural selection leaves the survivors '''STRONGER''' and '''BETTER'''."
* Parodied in the ''VideoGame/SamAndMaxFreelancePolice'' games with Stinky, an evilutionary ''cook'', who wants to advance mankind by making really bad food that only the strongest can survive eating.
* Abathur from ''StarCraftIIHeartOfTheSwarm''. He's a unique zerg specimen and responsible for all the evolutions and adaptations the zerg go through.
* Jaqueline Natla from the original ''VideoGame/TombRaider'' (but not the remake) who wanted to use Atlantis' powers to create a predator for humans, thereby giving evolution "a kick in the pants".
-->''"Evolution's in a rut, natural selection at an all time low. Shipping out fresh meat will incite territorial rages again, will strengthen and advance us. Even create new breeds."''
* The scientists who ran the White Orphanage in ''VideoGame/{{Wild ARMs 4}}'' fit this trope. They took orphaned children and used a variety of cruel methods to attempt to mass-produce artificially evolved humans who could use the eponymous [=ARMs=]. Of all their subjects, only 19 survived the initial experiments, and only 2 were not eventually killed or turned into mutated horrors.
* This trope forms the basis of the plot of ''VideoGame/WingCommander IV'', where the BigBad is [[spoiler:a WellIntentionedExtremist that let his extremism evolve into a Nazi Germany-style pogrom, including developing a nanotech-based bioweapon that kills based on preselected genetic criteria. It kills by destroying the cells of a infected person that doesn't measure up; liquefying the flesh of the person involved. Slowly. At first it's thought that it's a plague, until the main protagonist finds out the truth behind this, and another weapon that destroys ships by [[MadeOfExplodium somehow]] igniting the atmosphere within, turning spacecraft into impromptu furnaces) during a covert mission to the BigBad's stronghold/spaceship. It doesn't exactly help that the BigBad is a member of the same military that the protagonist is, and is actually higher in rank]]. The purported reason behind all this is that "humanity has gotten weak" without the perpetual warring of the first three games, and needs to be "pruned to be able to face the next adversary." Naturally, the protagonist has to stop this out of moral indignation, and the BigBad is deliberately inciting another war through his use of this stuff.
** The nanotech bioweapon doesn't liquify the flesh of the person involved... not directly, anyway. Instead, it alters the cells' RNA so that the person's ''own immune system'' attacks them, liquifying the flesh.
* In ''{{Headhunter}}'' the BigBad, unbeknownst to TheDragon, was creating a race of super-humans called Adam. He was also releasing a virus only Adam was immune to and if there were any humans left they would be quickly wiped off the face of the Earth by Adam. As I remember it there was only one creature (so no Eve) made and "he" didn't have any genitalia so how a new race was going to be built I don't know.
* In ''VideoGame/IHaveNoMouthAndIMustScream'', Nimdok's story involves him facing the fact that he was a Nazi Scientist and Josef Mengele's partner and atoning for his actions. [[HoistByHisOwnPetard His experiments later come back to bite him]] when AM uses them (for example, a Youth Serum created via the deaths of countless Jewish children) to torture him and the other remaining humans.
* Quite a few villains in the ''VideoGame/MegaManX'' series follow the robotic version of this, trying to improve the technological advancement of their species beyond what humans made them for. Lumine and Sigma (in the MHX remake) actually mention evolution.
** In the ''VideoGame/MegaManZX'', both [[spoiler: Serpent]] and much more notably [[spoiler: Master Albert]] fit this trope to a T. In addition, it is possible that [[spoiler: Master Thomas]] is an example of this trope as well.
* The primary plot in ''VideoGame/DragonQuestIV'' concerns the application of the "Secret of Evolution" to make monsters into more powerful monsters.
* In ''Franchise/MassEffect'', Shepard's crew can't go two weeks without tripping over ''some'' hideously immoral experiment. Usually involving [[NGOSuperpower Cerberus]] or [[BigBad the Reapers]] in some manner.
** [[spoiler: Sometimes BOTH.]]
** Mordin is a subversion. "No testing on species capable of calculus. Simple rule. Never broke it." He is, however, willing to engage in ''very'' DirtyBusiness - like upgrading the [[DepopulationBomb genophage]] - if he feels it will prevent future casualties. Mordin's loyalty mission involves his disillusioned student Maelon, who is willing to conduct brutal experiments to undo the damage they caused. Maelon admits that what he's doing is monstrous, but is already so disgusted with himself he feels he has nothing to lose. Despite this, [[spoiler:[[TheExtremistWasRight Maelon's research proves vital in the third game in securing a future for the Krogan]].]]
** In ''VideoGame/MassEffect3'', we finally meet Miranda's father, Henry Lawson, a man who [[DesignerBabies creates offspring]] based on [[{{Narcissist}} his own genetic template]] and then discards them when [[YouHaveFailedMe they don't live up to his expectations]]. After going through Sanctuary, where he [[spoiler: lured thousands of people promising shelter, only to turn them into husks]], it's clear that he's even more monstrous than Miranda said he was.
* The BigBad, Caulder, from ''[[VideoGame/NintendoWars Advance Wars: Days of Ruin]]''. Strictly speaking, "evolution" isn't his goal, but he is a MadScientist whose involvement in [[spoiler: cloning]] gets him pretty close to this trope. It turns out that [[spoiler: he is actually a clone who killed the original, then made clones of himself in an attempt to sell a clone army.]]
* The Riddler comes off as shades of this in ''VideoGame/BatmanArkhamAsylum'', [[SmugSnake justifying]] his actions by pointing out that if the residents of Gotham weren't so stupid they wouldn't die in his traps.
* In a sense, this is Mitra's motivation in ''VideoGame/ShinMegamiTenseiStrangeJourney''. On encountering humans, he begins experimenting on them to see what they can do without. The problem is that, since demons are made of spirit, he doesn't seem to understand that we need such things as "a functioning brain", "blood", "air", and "skin"...
* If you bring Lucca and/or Robo to the final battle in ''VideoGame/ChronoTrigger'', they reveal that Lavos has the DNA of all living creatures on Earth inside of itself. Then they work out why: Lavos ''caused'' human evolution from primitive cavemen to modern-day humanity. Why? Because it's a PlanetEater, and sentient life is more filling, particularly if it's intelligent.
* [[BigBad Dr. Merlot]] from the ''WebAnimation/{{RWBY}}'' video game ''[[VideoGame/RWBYGrimmEclipse Grimm Eclipse]]'' believes the [[TheHeartless Creatures of Grimm]] to be the ultimate form of evolution and has experimented on them to see how far he can take them to perfection and give them a purpose in life as also explained in his VillainSong "Lusus Naturae".
* One of those serving Zenos yae Galvus in the ''VideoGame/FinalFantasyXIV'' expansion ''Stormblood'' is the Garlean scientist Aulus mal Asina. Asina views the Empire's {{Magitek}} weaponry as "an extrinsic solution to an intrinsic problem," namely the Garlen race's [[UnSorcerer complete inability to use magic]]. With Zenos' personal endorsement, Asina has performed hundreds of human experiments to "correct" that issue and bestow magic powers on those who were not born with the ability, or further the power of one who could use magic to begin with.
* A newer addition to ''VideoGame/{{Overwatch}}'', Moira O'Deorain is single-minded in her pursuit of knowledge (when she spawns she says, "Science will reveal the truth,") and she has wound up working with [[NebulousEvilOrganization Talon]] because the multitude of ethical and moral issues with her experiments have made her such a controversial figure that she can't get work.

* Kim Ross of ''Webcomic/DresdenCodak'' has been moving closer towards this trope over time. Starting with [[TheSingularity a basis in technological transhumanism]], she's been stealing memories from hapless passersby to help create an AI model to help trigger this event. She tries to allow the time-travelling AI that practically lands in her lap to develop in the present, doing the same thing more quickly, ''despite'' the current evidence that says it'll probably wipe out most of humanity in the process. Currently she's gotten her hands on a mini-version and is uploading her model into it. Oh, and she's the protagonist. At the end of the arc where she encounters the time travelling AI, she has somewhat learned to not take her beliefs to the extreme of misanthrope and human inferiority the way her future self did.
* Parodied by ''Webcomic/SaturdayMorningBreakfastCereal'' [[http://www.smbc-comics.com/comics/20081030.gif here.]]
** And again [[http://www.smbc-comics.com/?db=comics&id=1695#comic here.]]
* Also parodied in ''Webcomic/EverydayHeroes'' -- as a ShoutOut to Marvel's High Evolutionary (mentioned above), two members of the S.A.V.E.U.S. team were created by the Somewhat-Below-Average Evolutionary.
* In ''Webcomic/EightBitTheater'', Red Mage has been known to dabble into this field from time to time, as a parody of chocobo breeding in ''Videogame/FinalFantasyVII''.
* Professor George Lonsdale, (the real) BigBad of ''Webcomic/{{Magellan}}'''s fifth chapter ([[http://magellanverse.com/?p=656 "Worst Field Trip Ever"]]). He truly believes that [[LegoGenetics splicing animal and human DNA]] is the next big evolutionary. But then he's also clearly shown as experimenting on innocents (including his own son) ForTheEvulz as much as anything else.
* In ''Webcomic/TheDragonDoctors'' Preston Chang turned himself into the Crax, a species that starts out as parasites until they grow to take control of their hosts and become amorphous blob creatures, Crax can adapt to practically anything but cold. All so that Chang could become immortal. Kili, the shaman, faces Chang in the spirit world twice, the first time when removing a Crax from a patient, his spirit is driven off and the parasite defeated. The second time he just shows up and drags her through a bunch of painful memories in an attempt to drive her to surrender her body to him, [[spoiler: then she realized she was talking to a ghost, the Crax's hyper-fast evolution had determined that Chang's megalomanical mind was a weakness and [[http://dragondoctors.dhscomix.com/archives/comic/ch-15-page-26 discarded him]], then evolved into harmless gut flora.]]
* Many mad scientists fall into this in ''Webcomic/{{Narbonic}}'' and ''Webcomic/SkinHorse'', some to create new life because it's somehow 'better', others because they just can. Helen Narbon, for example, likes gerbils, and one such product, Artie, notes how the gerbil is a much more ecologically sustainable form. [[spoiler:Near the climax of ''Narbonic'', a group of conservative-minded hamsters take this logic to its natural conclusion, seeking to wipe out almost all of humanity.]]

[[folder:Web Original]]
* Professor Hayle of ''Literature/{{Twig}}'' uses this philosophy in order to justify his decision to sink his deparmental funding into six separate projects, children with SuperIntelligence who would act as a gestalt. The plan is that the most successful project will be kept and expanded upon in order to iteratively improve the human brain until a firmly superior product is produced, but the fact that his project takes years to come to fruition means he has much less academic clout than his colleagues, who produce plagues, superweapons, and armies of reanimated corpses.

[[folder:Western Animation]]
* ''WesternAnimation/{{Futurama}}'':
** As well as the other ways in which he's a utterly raving MadScientist, Professor Farnsworth often rants about creating, amongst other things, a "[[Film/BrideOfTheMonster race of atomic supermen]]", which he once actually did in order to win a basketball game.
** ''Futurama'' also had an episode of its ''Series/TheTwilightZone'' parody, ''The Scary Door'', which featured one of these. He combined the most evil genes from the world's most evil creatures to form the evilest creature of them all:
--->"It turns out it's man."
* Doctor X, of the ''WesternAnimation/ActionMan2000'' animated series, was a textbook Evilutionary Biologist obsessed with triggering the [[EvolutionaryLevels next step in human evolution]] by causing all sorts of disasters in the hopes of culling unfit humans and cause beneficial mutations in the survivors.
* The villain of ''WesternAnimation/{{Felidae}}'' turns out to be doing this, with cats.
* Dr. Anton Sevarius of ''WesternAnimation/{{Gargoyles}}'' is a freelance geneticist specializing in clones and mutates. So long as he gets [[ForScience plenty of test subjects]] and money, he doesn't really seem to care ''what'' his creations are used for, having sold his services to almost every BigBad in the series.
* Dr. Paradigm from ''WesternAnimation/StreetSharks'' starts out like this, as evidenced by his monologue about how great his human test subjects will be post-transformation and sans those silly human morals. He abandons that pretty early and switches to simply taking over the town/world though.
** This is after getting a taste of his own medicine makes him seven kinds of AxCrazy though.
* ''WesternAnimation/XMenEvolution'' implies that ComicBook/{{Magneto}} is the one responsible for Nightcrawler looking like a demon, via one of his many, many experiments.
* ''WesternAnimation/LegionOfSuperheroes'' has Dr. Londo who was responsible for transforming [[GuineaPigFamily Timber Wolf]] into what he is now. It's also heavily implied that he wasn't the only test subject and subtly implied that he was aware of his father's work before he was transformed.
* Dr. Ketzer in ''WesternAnimation/ExoSquad'' was a genetic engineer who altered a group of villagers ([[ProfessorGuineaPig and himself]]) in the Amazon to give them plant-like abilities. He also infected [[spoiler: Nara Burns]] with the mutating agent as a ploy to get Marsh to do his dirty work for him.
* Dr. Eggbert Zygote from ''WesternAnimation/MightyMax''. His goal is to use his evolution machine to create a perfect race of humans. In practice, he mostly just makes monsters.
* Syrrus from ''WesternAnimation/DexHamiltonAlienEntomologist''. His goal is to breed an army of super insects to allow him to take over the galaxy.
* Victor Veloci from. ''WesternAnimation/DinoSquad'', who wanted to turn regular animals into prehistoric creatures and return Earth to the rule of the dinosaurs.
* Doctor Animo from ''WesternAnimation/Ben10'' was obsessed with advancing the evolution of planet earth ''[[TheUnfettered by any means necessary.]]''