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[[caption-width-right:248:[[{{Irony}} Something's]] [[FurryConfusion wrong here.]]]]

->''"Mice to me mean the little white furry things with the cheese fixation and women standing screaming on tables in early Sixties sitcoms..."''
-->-- '''Arthur Dent''', ''Literature/TheHitchhikersGuideToTheGalaxy1''

A staple of early domestic comedies in both film and television. The mere sight of a mouse (or sometimes another animal who is the subject of [[WhyDidItHaveToBeSnakes a common phobia]]) will drive a housewife up onto a chair or a table, where she stands shrieking, stomping her feet, and clutching the hem of her skirt until the rodent is captured or driven away. This is largely a DeadHorseTrope today, rooted in a very specific and sexist image of women [[ValuesDissonance dating back to the early part of the 20th Century]], but it is still visible in old WesternAnimation/LooneyTunes cartoons and in the odd [[ScreamsLikeALittleGirl ironic reference]].

Cartoons will sometimes [[PlayingWithATrope play with this trope]] by crossing it with the old myth (recently deemed plausible by the Series/MythBusters) about mice frightening elephants, resulting in elephants that shriek and leap up onto some (possibly insufficiently-strong) object upon sighting a mouse. Other ways to subvert this trope involve showing the wife standing unmoved while her ''husband'' shrieks and leaps to safety.

This trope is arguably justified by evolution. For the vast majority of human existence, the animals commonly associated with this trope--rodents, snakes, spiders, etc.--were potentially venomous or carrying disease, and a human's fear of it could be an evolved self-preserving instinct.

See also CowerPower and WhyDidItHaveToBeSnakes.

Not to be confused with ''EekTheCat.'' Also not to be confused with the Jamaican reggae artist "Eek-A-Mouse".

TruthInTelevision, as there is [[http://en.wikipedia.org/wiki/Fear_of_mice an actual condition, called [=musophobia=] or [=murophobia=]]].



* There was a commercial that had a woman do "EEK a Mouse!" bit and her husband hunts the mouse down but before he can dispatch it the wife see the mouse cornered and now it's a cute little mousey and she stops him. End of commercial has couple cuddling on the couch and mouse in a cage running on a wheel.
* [[http://www.youtube.com/watch?v=AKLyHTcZqOs This]] Samsung Infuse commercial, only with the image of a large spider.
* A cheese advert in New Zealand in the early 1990s featured local celebrity [[http://www.imdb.com/name/nm0168040/ Lana Coc-Kroft]] in this situation. She finds a wedge of Gouda cheese to ward off the mouse, only to frown and pause for a moment before eating it herself. Oops.

[[folder:Anime and Manga]]
* Freya from ''KenichiTheMightiestDisciple'' is, among other things, a BadAss LadyOfWar ActionGirl and has apparently eschewed femininity. However, she still freaks out when she sees [[SexyMentor Shigure's]] pet mouse.
* Used for a second in the last episode of ''GakuenAlice'', where Hotaru uses a gang of robot mice to keep two GirlyGirl classmates at bay.
* In ''Manga/HayateTheCombatButler'', Maria is scared of cockroaches (they even have a nickname within the story so they can be talked about around her). Shiranui brings one into the house and she shrieks standing on Hayate until he apparently shoos the kitten away. Still trying to figure out how he did anything with her standing on him like that.
** [[HandWave Don't worry]], [[RunningGag he trains]].
* In ''Anime/SaberMarionetteJ'', in order to make the marionette robots as much like (stereotypical) women as possible, every one of them is programmed to be afraid of mice -- except the tomboyish Lime, who merely finds them cute.
* ''{{Kekkaishi}}'' had [[LadyOfWar Tokine]] perform this trope, right after fighting a much bigger rodent ''that could breathe fire''. She and her grandmother also have a similarly disproportionate fear of cockroaches.
* In ''Manga/RanmaOneHalf'''s second movie, all the girls run away from a horde of mice. Ranma stands there unaffected and comments on how silly they are to be afraid of mice, until he discovers that cats are following said mice. [[WhyDidItHaveToBeSnakes At that point, he starts screaming in terror.]]
* In the ''GundamSEED'' VisualNovel ''Tomo to Kimi to Senjou de'', Athrun decides to make a robot pet for his crush Cagalli. He ends up giving it a hamster design, but when she first sees it she has this reaction and smashes it. Kira steps in and explains, and Cagalli is both very touched by the gesture and very apologetic for destroying it.
* ''Manga/{{InuYasha}}'': Kagome can handle {{youkai}}, blood, guts, wounds, two-timing boyfriends, time-travel, saving the world while trying to pass exams, lifting the spirits of the depressed, downtrodden and bullied and can even befriend the reclusive, the painfully shy, and aggressively hostile, but ask her to help a giant beast-faced [[HalfHumanHybrid hanyou]] in his herb garden when there's an earthworm in plain sight and she'll fall to pieces.
* In ''Manga/DragonBall'', Goku is fighting General Blue of the Red Ribbon Army. Blue has Goku paralyzed with telekinesis, and is about to finish him off...when a small mouse appears. Blue flips his lid, freaks out, and loses focus. Goku is grateful enough for the unwitting save that he rescues the mouse when the cave they're fighting in collapses.
* ''Manga/AiYoriAoshi'': Miyabi is capable of bodily throwing someone across the room if she even ''suspects'' someone is trying to [[MamaBear harm Aoi]], but completely flips her lid at the sight of bugs. Unfortunately for her, the Sakuraba house's pet ferret, Uzume, develops a habit of bringing her dead bugs.

* ''Franchise/{{Tintin}}''. The Thomson twins are startled by mice used for experiments in "Recap/TintinDestinationMoon".
* This once happened in ''{{Archie}}'' when Ms. Grundy jumped on her desk and Jughead took a picture of it for the school newspaper. She actually was worried that the picture would be about how scared she was of a little mouse but instead it turned out to be proof the school needed an exterminator.
* The protagonist of ''ComicBook/JenniferBlood'' takes advantage of this stereotype in issue 3, when a neighbor who's convinced she's attracted to him has cornered her in a bathroom and exposed himself to her. She doesn't want to ruin her "perfectly ordinary suburban housewife" facade by maiming or killing him, but as someone who moonlights as a brutal {{Vigilante}}, that's all she's trained to do. So she starts shrieking about a pretend mouse.

* The main plot of the ''FanFic/CalvinAtCamp'' episode "Bringing Down the Mouse."
* ''[[FanFic/TheRockFarmersDaughters The Rock Farmer's Daughters]]'': Taken to an unusual extreme in the chapter titled "Unusual Incentive": [[spoiler:Marble opens a cupboard, and a waterfall of mice ends up falling onto her head, while everypony else finds mice seeping out of every nook and cranny. Cut to Igneous and Maud outside, hearing Marble shriek. She spends most of the chapter curled up on the table while the others drive the mice out of the house]].

* There is a scene in ''Film/ConanTheDestroyer'' where Grace Jones' character, who up until now has been afraid of nothing, taking on whole villages and men much larger than her in combat fearlessly, jumps and screams at the sight of a mouse. When all of her party look back she looks sheepish.
* The 1959 movie ''Literature/TheMouseThatRoared'' opens with the Columbia Studios girl-with-torch logo suddenly hiking up her gown and fleeing from a mouse at her feet. (The title is a metaphor for a tiny, innocuous nation that ends up holding the fate of the world in its hands.)
* The 1934 film ''Hollywood Party'' has a whole roomful of women doing this when one of them sees a mouse. It turns out to be [[ClassicDisneyShorts Mickey Mouse]].
* In ''ShesTheMan'', Duke and Viola scream and leap on the bed, hugging each other, when a big spider enters their dorm room.
* The two female leads in ''EightHeadsInADuffelBag'' take this kind of behavior UpToEleven when they find a disembodied head in their luggage during a family vacation. ("Eek, A Head!"?) One shuts herself up in a closet and refuses to come out (until the protagonist jokingly suggests that the dead guy's body might be in there), while the other ''attacks the protagonist with a fork''. The latter is especially hilarious because what causes her to snap is the protagonist innocently asking, "Would you like an enchilada?"
* Disney's ''BedknobsAndBroomsticks'' has the "mouse frightening an elephant" version. During the animal soccer game on the Island of Naboombu, an alligator uses a mouse to scare the elephant goalkeeper of the opposing team.
* Timothy Q. Mouse uses this to his advantage against the cruel female elephants in ''Disney/{{Dumbo}}''. Sure, those "over-stuffed hay-bags" can be mean to a little elephant with super-huge ears, but facing Timothy? They're scared to near-stampeding!
* ''WesternAnimation/AnAmericanTail'', in the scene with the wax cylinder gramophone.
* During the Wizard's Duel in ''Disney/TheSwordInTheStone'', Madame Mim turns into an elephant, and Merlin counters by turning into a mouse, scaring her.
* ''JourneyBackToOz'' has the returned Dorothy scaring off Witch Mombi's elephant army with a herd of magical white mice.
* ''MoscowCassiopeia'' has a rare male example. Lob tears through the entire ship and ends up [[spoiler: accidentally causing it to [[FTLTravel travel faster than light]]]] all because of a mouse. May be justified, as the window was blown up and made tiny Pacnuty seem like a giant monster.
* In one scene in ''Film/{{Willow}}'', a woman shrieks at the sight of mouse-sized humanoid creatures called brownies.
* Invoked by Becky in the Alfonso Cuaron version of ''ALittlePrincess''. As the students are stealing Sarah's locket from Miss Minchin's office, Becky screams to distract Minchin and eventually stammers that she thought she saw a mouse.
* Lt. Alexis in ''Film/TheWildcat'' is TheCasanova to an absurd extreme. When it's time for him to leave for his next duty station on the frontier, literally hundreds of women throng the streets, obstructing his car. The other soldiers finally get the crowd of ladies to disperse by dumping a barrel of mice.

* In ''[[Literature/LandOfOz The Marvelous Land of Oz]]'', Scarecrow and his friends enter his palace (taken by rebels), and are captured immediately, to be brought before their leader. However: 1) the rebels are all women and 2) Scarecrow has recently met the Queen of the Field Mice and asked for permission to take a few of her subjects along.
* In ''TheWitches'' Bruno's mother flips into hysterics when the [[spoiler: witches start turning into mice thanks to drinking their own potion]]. She literally climbs over her husband screaming about them climbing up her skirt. Although in this case it's completely understandable since there are over a '''hundred''' of them running around.
* In one of the ''Clue'' mystery books, Mr. Boddy reveals that several white mice have escaped. The first one to actually do this trope is the duel-crazy Colonel Mustard, but the other guests don't laugh because they're doing the same thing.
* The non-fiction book that inspired ''HomicideLifeOnTheStreet'' mentions that one of the detectives had been called home by his wife to deal with a rampaging mouse. "I disposed of the body, but considered leaving it as an example to others."
* Happens in a ''Literature/DoctorDolittle'' story: A smaller African kingdom is warred upon by a bigger, expansionist one, whose crack troops are Amazons. The White Mouse who lives in Dolittle's pocket points out that while they are fearsome warriors, the Amazons [[ValuesDissonance are still women]], and gather a force of local mice who scares them away.
* Played with and justified in the last Hawk & Fisher story, where a crime lord keeps a bunch of naked Amazons as bodyguards. Rather than fight them, Hawk and Fisher turn a sackful of ravenous sewer rats loose in the crime lord's lair, and the bodyguards start climbing the furniture in a panic when the starving rodents swarm them to bite their bare toes.
* In ''Literature/TheChroniclesOfNarnia'', BadassAdorable Talking Mouse Reepicheep wants to be a herald, but he's too small to be seen until he's up close (and therefore not very impressive). Of course, since he's [[{{Badass}} very]] [[BerserkButton touchy]] [[HonorBeforeReason when it comes to his honor]], nobody wants to tell him this, so they tell him that it wouldn't be quite fair to their enemies since some humans are afraid of mice.
* In ''Literature/{{Mousenet}}'', this is part of the "EEEK Test," a test used by mice to gauge a humans' feelings towards mice. Jumping on a chair results in a "Loud EEEK" and a grade of C, with fainting being the worst possible response and earning an F. Talking to or touching the mouse is "No EEEK" and an A+.
* In ''Literature/TheHitchhikersGuideToTheGalaxy1'', Arthur Dent associates mice with cheese and women standing screaming on tables in early Sixties {{sitcom}}s.
* Defied in the LordPeterWimsey book "Strong Poison":
-->'''Mr Pond:''' You're not afraid of mice apparently?
-->'''Miss Murchison:''' No. In [[TheGayNineties your days]] I suppose all women were afraid of mice.
-->'''Mr Pond:''' Yes, they were, but then, of course, their garments were longer.
-->'''Miss Murchison:''' Rotten for them.
* ''The Bronze Horseman'' by Paullina Simons. Alexander is rather bemused when his young wife Tatiana has this reaction, as he's seen her brave 500-kg bombs, cannibals and starvation in the Siege of Leningrad.

* The ''Series/ThreesCompany'' episode "The Best Laid Plans" revolved a mouse being loose in the trio's apartment. Larry kills the mouse, but Jack doesn't want the girls to find out because Janet won't sleep in her bed as long as the mouse is around and Jack is using it as an excuse to sleep in the same room as Chrissy. Meanwhile, Mr. Roper doesn't want Helen to know the mouse is dead because he was using it as an excuse for Helen's mother to not visit.
** Spinoff the ''Series/TheRopers'' featured a gender-flipped version of this trope: it was ''Mr.'' Brooks, not his wife, who leaped up onto the couch screaming at the sight of a white mouse--safely in a cage, no less.
* [[{{Monk}} Adrian Monk]] frequently [[ScreamsLikeALittleGirl reacts this way]] to a variety of analogous situations.
** Justified in the episode when it was a ''venomous snake'' that was loose in the room.
* Played with on HopeAndFaith: when the two title characters get office jobs together, the ever-immature Faith dangles her computer mouse into Hope's cubicle and yells this trope name.
* ''TheGoldenGirls'' had one, revealing why Dorothy's nickname is Pussycat. Instead of catching it as the other girls expect her to, Dorothy talks the mouse into escaping.
* Used in an episode of the Adam West version of ''Series/{{Batman}}''; villainess Nora Clavicle manipulates Gotham City into hiring only women police officers, then unleashes an army of tiny mechanical mice. At least Batgirl remains "immune".
* Referenced in ''Series/TheGoodies'' episode "Kitten Kong", where a housekeeper (suspiciously similar to the one in ''Tom and Jerry'', we even hear her shouting for "Thomas") jumps on the table and shrieks at the sight of the team dressed as mice.
** Also referenced (and inverted) in ''Punky Business'' when a mouse trying to assure Tim that he is ugly tells him that when he walks into a room all the mice jump onto a chair.
* On ''ImaginationMovers'', Knit Knots wasn't scared by Warehouse Mouse to the point of panic, but did urge the Movers to keep the "woodland creature" away from him. An episode of the show also focused on the Movers helping a TV repairman to get over his fear of mice, so that he could stick around to fix their TV and not be afraid of Warehouse Mouse.
* An amusing variant happened on ''XenaWarriorPrincess.'' Gabrielle (not ''quite'' an ActionGirl yet) was hiding from some bad guys when she noticed a rat crawling about. She had to remain perfectly still and silent lest she blew her cover, and HilarityEnsues as she stares at it with wide eyes and covers her mouth before a whimper comes out.
* Double-subverted on an episode of ''UnhappilyEverAfter''. Ryan, who believes the old legend that the Earth would spin out of its orbit if all the Chinese people in the world jumped off their chairs at the same time, panics when he spies a group of Chinese exchange students standing on their chairs in the school cafeteria. One of the students explains that they had just seen a mouse, causing Ryan to calm down. Once Ryan is gone, though, the student gets angry and mutters: "Curses! They're onto us!"
* The late 80s sitcom ''Kate And Allie'' spent an entire episode dealing with a mouse, complete with jumping on chairs and tables in fright(Allie's son Chip was taking care of his classroom's pet mouse and it got out of its cage). Subverted in that 1) they realized that they were [[GenreSavvy behaving like 60s sitcom housewives]], 2) Kate and Allie were running a catering business at the time and were justifiably concerned about mice on the premises, and 3) Allie's sportscaster boyfriend also turned out to be deathly afraid of mice.
* As mentioned in Real Life below, the "Elephants are afraid of mice" variant was tested by the ''Series/MythBusters'', who were stunned when the elephant actually stopped dead in its tracks at the sight of the mouse, and gave it a wide berth when walking around it, rendering the myth plausible.
** When testing the effects of mood on gas consumption, Grant was forced to drive a course while a pair of mice were allowed to run loose inside the car; his reaction screamed this trope.
--->'''Grant''': *upon realizing he lost track of the mice* [[OhCrap Where did you go?! WHERE DID YOU GO?!?]]
* A late episode of ''Series/ElChavoDelOcho'' has Doņa Florinda's restaurant plagued by mice. She and Chilindrina exhibit the expected reaction throughout, especially in a hilarious scene where Chavo unknowinlgy brushes the latter's leg with the broom he is using to hunt the mouse; she has an absolute panic attack, thinking it's the mouse climbing up her leg.
* This is how Ma Gorg reacted to Fraggles on ''FraggleRock''.
* In ''Series/{{Community}}'' episode [[Recap/CommunityS1E10EnvironmentalScience Environmental Science]] Troy freaks out when a lab rat accidentally escapes.
* In the Mexican SoapOpera ''Series/{{Carrusel}}'', [[ThePrankster Pablo]] releases a mouse in the middle of class. All but one of the girls start screaming and crying. [[spoiler: The one girl who isn't scared, [[{{Tsundere}} Valeria]], "punishes" Pablo by pretending to pass out and tricking him into believing she had a heart attack.]]
* In a ''SexAndTheCity'' episode, Charlotte dates a CampStraight man and they both react to a mouse in a similar way.
* ''Series/PanAm'' has Laura reacting this way to the appearance of a lizard in her hotel room in Rangoon, as she jumps on her bed to get away. Maggie calmly appears to pick it up and put it outside [[spoiler: then joins Laura on the bed shrieking upon discovering a snake in the bathroom]].
* Averted in the premiere episode of ''Series/BuffyTheVampireSlayer''. The heroine doesn't even twitch when a sewer rat runs over her foot.
** And subverted in its spin-off ''Series/{{Angel}}'' when Gunn and Wesley freak out over a rat and Cordelia is the one to get up and deal with it.
** Buffy does jump at a sewer rat in "I Will Remember You", but that's a sign that she's nervous over [[UnresolvedSexualTension working closely with Angel]].
* The ''MyWifeAndKids'' episode "Of Mice and Men".
* On a late 1960s episode of ''TheTonightShow'', Johnny Carson freaks and jumps into Ed [=McMahon=]'s arms after a cheetah cub hisses at him.
* Jane on ''TheMentalist'' once escaped from jail by scaring a rodent-phobic guard with a live mouse he'd caught.
* Exploited in ''TheWorstWitch'' when Helibore and Rowan-Webb have a wizard duel (no not [[Franchise/HarryPotter like that one]]). Helibore turns Ethel into a goose girl and Rowan-Webb counters by turning himself into a mouse to scare her.
* In the 1990's Australian mini-series ''Phoenix'', the [[TheSquadette only female member]] of the Major Crimes Division is mocked by her sergeant when she has a fender-bender accident after a spider drops out of the sun visor in front of her. At the end of the episode, he hands her a can of bug spray and declares he's not going near that car until "that horrible monster" has been killed.
* Happens with Alice on ''TheBradyBunch'' when a pet mouse gets loose. Although, it's averted another time-she hands it to the boys and isn't scared.
** In a different episode, Cindy runs into the kitchen asking Alice if she has seen her pet lizard that escaped its box. Through a clenched-teeth smile, Alice answers, "Yes I have. He's over there." Camera zooms out to reveal that Alice is standing on the table.
* ''{{Dollhouse}}''. At the start of Season 2, a pissed-off Dr Saunders puts lab rats in Topher's cupboard, in a not-too-subtle message of what she thinks of him. His female assistant Ivy has to retrieve them while Topher climbs the nearest railing to get away.
* ''DangerUXB''. A sapper screams when he encounters a rat, just when Lieutenant Ash is about to defuse a bomb designed to blow up at the slightest touch. [[{{Understatement}} He's not impressed.]]
* Cousin Serena in ''Series/{{Bewitched}}'' both invoked and inverted the trope with this line about a woman she found disgusting. "I'll bet when the mice see her, THEY climb up on chairs."

* Played with in one ''{{Garfield}}'' strip, where Garfield screams and scurries up onto Jon's head upon seeing a mouse - and Jon is disgusted, because Garfield is a ''cat''.
** [[http://www.garfield.com/comics/vault.html?yr=2004&addr=040909 Garfield did it in consideration for the mouse's birthday.]]
** [[http://www.garfield.com/comics/vault.html?yr=2009&addr=090824 Jon yelled "Eeeeeeek!"]] then he said "Um... I mean, get the mouse." Garfield said it'd go into his blog.
** ''USAcres'': [[http://garfield.com/us-acres/1988-07-16 A worm had this reaction after entering a mouse hole to hide from Booker.]]
* ''CalvinAndHobbes'': Calvin once tried to gross out Hobbes by telling him he had a loathsome bug hidden in his hands. When Hobbes asked if it was a centipede with poison pincers, Calvin did an OhCrap, dropped the bug, and jumped into Hobbes's arms, declaring: "It's a lucky thing you guessed so fast!"

[[folder:Religion and Mythology]]
* According to one of the stories about the Chinese calendar, the reason why the rat is the first in the list instead of the ox is this trope. The people were shown the ox and the rat, and only the rat was called "huge". Well, if it's bigger, then it should be first.

* ''A Challenge of Arms'' had a ''mastodon'' that was afraid of mice.

* Ellie in ''VideoGame/DonkeyKongCountry 3'' is an elephant who rapidly runs away from any Sneeks (basically rats) that she sees. One level requires the player to either dispatch the Sneeks from a distance or in the dark (apparently, she doesn't mind if she can only barely see them), and another features her running madly away from a trio of Sneeks, with the player only able to control her jumping until she settles down.
** Also quite funnily used in the 101% ending of ''DonkeyKong64'', where Dogadon (aka the huge dragon who's fought twice in the game) is scared of a tiny mouse squeaking. Well, among various other jokey scenes, as seen [[http://www.youtube.com/watch?v=BZihf09JkLU here]]
* Princess Zelda in ''VideoGame/TheLegendOfZeldaSpiritTracks'' reacts to mice in that manner. Not that that makes her any less [[LadyOfWar awesome.]] Although it is a bit silly seeing her cower when she's [[BodySurf animating a steel-clad phantom]].
** And hence why stage 2 of the final battle has Link having to take down the ghost mice used to attack Zelda by Chancellor Cole.
* Played with in ''VideoGame/GalaxyAngel'', where in an AmazonBrigade full of girly-girls, the one with the paralyzing phobia of mice is the [[MightyGlacier powerful]] and [[BoobsOfSteel intimidating]], [[RareGuns Rare Gun]]-collecting, ultra-violent {{Bifauxnen}} Forte.
* [=HanPan=] from ''WildArms'' uses this to his advantage in several places in the game to spook certain [=NPCs=] and make them move.
* ''VideoGame/DragonQuestVIII'' has [[PrinceCharmless Prince Charmless]] who [[DirtyCoward refuses to undergo the hunt for an Argonian Lizard]] to prove he's worthy of the throne because he's afraid of lizards. All lizards. Even little ones. You have to scare him out of a room he's holed himself up in at one point by nudging a lizard into it, provoking this trope as a reaction to it.
* Mongoria from ''VideoGame/ComixZone'', an otherwise extremely formidable enemy, had this as her weakness.
* Elh from ''{{Solatorobo}}'' absolutely ''hates'' bugs and insists that Red kill them as quickly as possible when you come upon them (which is a good idea, since the bugs attack you [[EverythingTryingToKillYou like most everything else in video games]]). There are also ''two'' {{Protection Mission}}s in which the goal is just "don't let the bugs get near Elh" (this includes if you accidentally throw a bug across the line, because apparently even a dead bug is creepy).
* Played with for a laugh in ''VideoGame/FinalFantasyIX''. [[KingIncognito Incognito princess]] Garnet picks up an oglop (a beetle-like insect), having no problem with the little critter whatsoever. However, since she's supposed to be undercover as a normal country girl, when an old woman comments that most girls hate them, she squeals theatrically and flings it into the air.
* Can be invoked for rewards in the [=PS2=] release of ''VideoGame/TheBardsTale'', by summoning and dismissing the rat in bars. In fact, this is how the eponymous Bard starts the game.
* In a skit in the UpdatedRerelease of ''[[VideoGame/TalesOfGraces Tales of Graces]]'', ''Tales of Graces f'', Cheria is freaked when Sophie discovers a mouse in Pascal's invention, Mecha-Asbel.
* Frog in ''VideoGame/ChronoTrigger'' manages to frighten Lucca when they first meet. Later, if Marle is in the party when Crono and Lucca see him off from Guardia Castle, he'll approach Marle to comment on her resemblence to Leene, prompting her to shriek.
* In ''VideoGame/BrainLord'', Ferris screams her head off when she encounters a room full of mice in the Tower of Light.
* Monomi and Monokuma in ''VisualNovel/SuperDanganronpa2'' are revealed to be terrified of mice in chapter 4.

* Often Florida wildlife will invade the live webcast of ''TheFundayPawpetShow'', leading Ezra to envoke this trope, while Mutt commands the show's border collie to "Eat it, Bandit! Eat it eat it eat it!"
* The {{Facebook}} game ''MouseHunt'' features the king of Gnawnia hiring a team of mouse hunters to rid Gnawnia of their mouse problem.
* ''WebAnimation/PorkchopNFlatscreen'' has a mouse showing up and scaring...the girl called Mouse. She panics and tries to smash it with a baseball bat, which then flies out of her hands, conks her on the head, and lets loose her SuperpoweredEvilSide.

* Referenced in ''WesternAnimation/SouthPark'' episode "Eek, A Penis!" where a mouse frightened women with a genetically engineered human penis growing on its back. Actually they were frightened by the penis. But the trope still stands.
* Monterey Jack actually uses this trope in the ''WesternAnimation/ChipNDaleRescueRangers'' episode "The Carpetsnaggers" to chase humans from one side of a flying house to the other to prevent it from hitting any buildings.
* Done many a time in ''WesternAnimation/TomAndJerry''.
** Including a short where the "Eeker" was Tom's cowardly identical cousin.
** The Elephant variation is averted in one episode where Jerry befriends a baby elephant, then disguises '''''it''''' as a giant mouse.
** Averted in one episode when the lady who owns Tom ''buys'' a pet white mouse.
** Played straight and then subverted in an episode of WesternAnimation/TomAndJerry where during the usual chase, Jerry stumbles on a circus elephant weeping from a tack stuck under its foot. Jerry removes the tack and the elephant panics, afraid of Jerry (as he is a mouse), desperately [[GrievousHarmWithABody trying to hit him with Tom]] (who happened to be there at that moment) like a drum on a stool. Jerry shows the female elephant the tack and, in AndroclesLion fashion, hugs Jerry in appreciation. From then on, she treats Jerry like her own child, [[MamaBear protecting him]] from a persistent Tom in addition to giving the cat a good beating.
** The Gene Deitch short "Sorry Safari" has the elephant that's carrying Tom and his master getting frightened of Jerry when Tom sticks him in his trunk.
* Several old ''WesternAnimation/LooneyTunes'' shorts utilize this trope, usually starring SylvesterTheCat. ''Lighthous Mouse'' is one example.
** In one short, a mouse mocks the way the housewife panics.
* Also played with in the ''RenAndStimpy'' short "The Boy Who Cried Rat", in which Ren impersonates a rodent so Stimpy can earn his keep by catching him.
* The Dog's reaction to rats in ''FootRotFlats''. The cat, Horse, has the opposite reaction.
* In the premier episode of CourageTheCowardlyDog, Courage was afraid of a mouse in the beginning. Muriel plucks the little rodent and sets it loose outdoors. But after the battle with ''The Chicken From Outer Space'', we see Courage looking at it again as it fed on the ashes of the fallen fowl. [[RedEyesTakeWarning The mouse's eyes turn bright red]] as a result. It was a JustifiedTrope as Courage screams in terror.
-->'''Courage:''' This shouldn't happen to a dog!
* Bella from ''FiremanSam'' often freaks on seeing mice, regardless as to whether they're real or clockwork ones.
* ''TitanicTheLegendGoesOn'' had a scene where Angelica's stepsisters were scared by mouse.
* ''[[VideoBrinquedo Ratatoing]]'' plays this trope straight too.
* In the special ''Toot and Puddle: I'll Be Home for Christmas'', the boarding of Toot's train home is delayed by an elephant who doesn't want to be left alone in jumbo class. He's afraid that a mouse might sneak in. When Toot expresses disbelief that a big guy like him would be terrified by a small mouse, the elephant responds "What can I say? It's genetic." Toot agrees to ride with him to watch for mice.
* Subverted in ''TheSimpsons'' at Apu's wedding. When a mouse runs out in the the elephant's path, the elephant recoils for a moment... and then proceeds to deliberately step on it.
* The premise of many of the TomAndJerry and HermanAndKatnip shorts, only with the mouse as the hero of the story.
* Taken to ridiculous lengths in an episode of ThePowerpuffGirls where a rivaling villain reanimates a mammoth (which appears as comically large as any city destroying monster) to cause destruction in Townsville. To stop it, Mojo-jojo instructs the girls to leave a large hunk of cheese to attract the town's mice and scare the mammoth off. And you know what? It works!
* The main villain of the second half of Disney's ''Disney/GoliathII'' is a mouse in which only the titular elephant can get rid of.
* Creator/TexAvery, naturally, built an entire cartoon out of this trope. "Slap Happy Lion" has a mouse scaring a much-feared lion simply by saying "Boo!" at him. The cartoon ends with the mouse being scared by a much smaller mouse.
** The narrator of that cartoon- a mouse- even wonders why anyone would fear a mouse.
* Stu from ''{{Rugrats}}'' has a moment like this when he discovers the thing wrecking his garage wasn't a rowdy Spike, but a mouse. He even apologizes to his dog when he "saves" the day by chasing it away with a bark.
* The film ''Of Unknown Origin'' is about a New Yorker obsessed with eliminating the large rat that keeps invading his apartment.
* When Captain Fanzone winds up on Cybertron in ''TransformersAnimated'', this is basically the Transformers' response.
* In the silent ''KrazyKat'' cartoon "Krazy Kat and Ignatz Mouse at the Circus", Ignatz [[GenreSavvy knowingly employs this trope]] this to scare a woman in the circus dressing room. When Krazy tries it himself, he gets hit with a broom.
* In ''[[{{Disney/Cinderella}} Cinderella III: A Twist In Time]],'' Jaq and Gus help Cinderella get into the palace by scaring the kitchen servants while Cinderella poses as the "royal mousecatcher".
* ''WesternAnimation/WhoKilledWho'' has a ghost who scares the protagonist, laughs, then promptly gets scared of a tiny mouse, in the classic housewife way.
* ''WesternAnimation/WildWestCowboysOfMooMesa'': When a circus arrived in town, Mayor Bulloney tried to use a mouse to scare an elephant so the resulting distraction would allow Saddlesore and Boothill to steal a diamond.
* Happens in the ''WesternAnimation/DangerMouse'' story arc "The Great Bone Idol." Count Duckula steals the idol and awakens a herd of elephants in the underground cavern in which DM and Penfold had traversed to locate the idol. The elephants naturally freak out.
* [[TVTropesWillRuinYourLife TvTropes must have ruined the life of someone involved in making]] ''WesternAnimation/SpongebobSquarepants'' There's an episode that's actually called "Eek, an Urchin!" which involves the titular creature terrorizing the Krusty Krab.
* Employed and then subverted in ProducingParker when Parker shrieks at the sight of a mouse in Dee's office. Dee, who has been turned into a human/reptile hybrid by experimental snake venom-based drugs, promptly [[{{Squick}} claps her jaws shut on the little critter and gulps it down]].
* In ''Series/{{Thunderbirds}}'', The Hood sneaked a camera disguised as a mouse aboard Thunderbird 2. The plot failed, because it was attracted to, and only photographed, the screaming Lady Penelope.

* While elephants don't typically leap onto small objects at the sight of a mouse, research has provided a possible reason for the elephant's fear of mice: an elephant's eyes are located on its head in approximately the same position as a human's ears -- add this to the elephant's large body, (relatively) poor eyesight, and sensitive hearing, and what the elephant sees turns from a small, furry rodent into a small, barely-visible, blurry and mostly-unidentifiable squeaking blob somewhere near its feet. It was tested by the ''Series/{{Mythbusters}}''. Myth Plausible.
** If a mouse is ''brought close and shown'' to an elephant, however, it's generally not alarmed in the slightest, and may even lift the rodent in its trunk for a better view. The reality may be that elephants are wary of '''any''' small moving critter on the ground, just in case it turns out to be something a lot nastier than a mouse (e.g. a scorpion or coiled-up cobra).
* Semi real-life, with another type of vermin rather than a mouse: The late XJapan guitarist Hide and the drummer/bandleader Yoshiki were/are both terrified of cockroaches. One story has it that when the band members were in Los Angeles for the first time, a roach had gotten into the room hide and Yoshiki shared. This trope ensued with both, according to the story, jumping up onto the bed and shrieking until it was finally agreed that ''someone'' had to kill the roach, and depending on who's telling the story, either Hide or Yoshiki finally did.
* Psychologists who studied the Eek, a Mouse!! phenomenon concluded that it's not the mouse itself which the typical distressed housewife is afraid of, but her awareness that she'll probably have to ''kill'' the animal to remove it from her residence. The mouse is harmless, killing is Squicky.
** Besides, as humans have co-evolved with mice ever since the dawn of agriculture, screaming, shouting and stamping if a mouse enters your kitchen is a moderately sound response- perfectly sensible for a woman to aggressively protect her food-store by trying to frighten away small invaders.
%%* In the nonfiction book ''Retail Hell: How I sold my soul to the store'', this happened in the "Big Fancy" store when someone returned a product to the handbag department that had a ''huge'' Cockroach in it. Naturally; this trope ensues and Freeman is told to kill it as the ''sole'' male working the department.
* In RealLife, there's very good reason to be afraid of mice. House mice in particular [[http://en.wikipedia.org/wiki/House_mouse#Mice_and_humans can carry deadly diseases]] and there have been reports of ones growing so large they attack albatross chicks nearly one meter tall. In addition, in 1993, Australia was beset by one of the most devastating mouse plagues in the world; mice began eating the '''livestock''' alive.
* Inverted with mice and rats as pets, which are far more popular with women than men. This was even so in Victorian times, where some upper-class young ladies would keep them almost like [[MisterMuffykins toy dogs]].
* Actress Jaimie Alexander has admitted that, while she has no problem with things like snakes or spiders, she is ''terrified'' of mice. You read that right - [[Film/{{Thor}} The warrior goddess Sif]] is afraid of mice.
* In the pregame of the Florida Panthers's home opener in 1995, a mouse entered the Panthers locker room and startled the players. One of them hit the animal with his stick. Given in that same game he scored two of the goals in the 4-3 victory, [[http://en.wikipedia.org/wiki/Rat_trick Panthers fans embraced the rat theme with pleasure]], [[ProducePelting including throwing plastic mice into the ice every time a goal was scored]] (nowadays doing that after ''every'' goal becomes a two-minute delay-of-game penalty on the Panthers, something which is of major concern for the Panthers if unscrupulous fans of the opposing team toss a rat onto the ice to try to snag a cheap power play).
* AkiraToriyama, creator of ''DrSlump'' and ''Manga/DragonBall'', has an intense fear of mice, such that his work suffered when his workplace had an infestation, since he was too scared to step inside.
* [[http://www.bbc.co.uk/news/world-us-canada-26963256 Rat on New York City subway scares passengers]]
* In the nonfiction book ''Retail Hell: How I sold my soul to the store'', this happened in the "Big Fancy" store when someone returned a product to the handbag department that had a ''huge'' Cockroach in it. Naturally; this trope ensues and Freeman is told to kill it as the ''sole'' male working the department.
* "[[http://www.youtube.com/watch?v=dQRKjoAr_q8 Soldiers vs Camel Spider]]", a hilarious Youtube video where a pair of muscular, manly American soldiers are standing on their beds ([[ShirtlessScene in their underwear]]) and hunting down a camel spider in their room...WITH RIFLES.
** While "camel spiders" (which aren't spiders) are not actually very dangerous, there's a ''lot'' of misinformation out there about them, most of which makes them sound [[ScaryScorpions scarier than they are]]. Freaking out is predictable if you think something can literally gouge out chunks of your flesh.