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[[caption-width-right:320:"Some assembly required."]]

->''"They used to say that a child conceived in love has a greater chance of happiness. They don't say that anymore."''
-->-- '''Vincent''', ''Film/{{Gattaca}}''

One of the biggest downfalls of LegoGenetics is the fact that it's hard to modify an adult. They're already done with development and cell specialization and the idea seems a bit far fetched to most people. It's like putting flour on a cake after it's been baked.

If you modify humans before they're born, however, then it's far more plausible, because foetuses are mostly stem cells that can be modified into any cell. DesignerBabies are what occurs when you [[ArtificialHuman create]], or [[GeneticEngineering genetically engineer]] embryos and then implant them into a womb (either the original mother's or, especially in the case of completely artificial genomes, a host mother's) or a UterineReplicator.

The resulting child is often seen either as a more perfect, beautiful and wonderful {{Transhuman}} than normal people, or as a freak/monstrous UncannyValley who should have never existed and must now be destroyed -- and sometimes both at the same time by different groups of people. This is often a [[GeneticEngineeringIsTheNewNuke source]] of StockSuperpowers. It's also frequently the purview of the EvilutionaryBiologist, who believes that humanity can be "[[{{Transhuman}} improved]]" if they would only allow him to tinker with nature a bit. WhatCouldPossiblyGoWrong

It is not uncommon to have settings, especially in ScienceFiction of the {{Dystopia}}n variety, in which most or all humans are produced via genetic engineering/cloning, sometimes forced into physical and mental specializations similar to a HiveCasteSystem. This is often done in an effort to "perfect" humanity in a belief that nature is stronger than nurture. [[GuiltByAssociation Parallels with Nazi]] [[GodwinsLaw Eugenics are likely]]. In almost all of these settings, there will be a group of people who want to make babies the "natural" way. Whether they're right depends on which side of ScienceIsBad the {{Aesop}} of the work falls on.

See also the EvilutionaryBiologist and SocialDarwinist. Compare DarwinistDesire and GeniusBreedingAct.


[[folder:Anime & Manga]]
* Team Summer A and its candidates in ''Manga/SevenSeeds'' were all created by picking only superior sperm and eggs to fertilize, so they would have inherently improved skills, reflexes and looks from birth onward.
* That's a big part of the premise behind ''Anime/SaberMarionetteJ''.
** Considering that men were the only survivors. Which doesn't make a lot of sense when you consider you CAN clone females from males. If women were the only survivors, it would make more sense. [[ArtisticLicenseBiology But at the end of the day, that's not really important]].
* An interesting variant occurs in ''Anime/{{Simoun}}'', in which one of the enemy nations has replaced the traditional method of sex selection among the HumanAliens who populate the world: instead of everyone being female until 17, and choosing a sex then, the enemy nation assigns sexes to babies shortly after birth through hormones and surgery.
* ''Anime/{{Monster}}'' includes a more realist variation on the concept- the babies produced by Franz Bonaparta's program [[spoiler:including Johan and Anna/Nina]] are conceived in the normal way and carried by their own biological mothers, but their parents were handpicked by the program's supervisors and manipulated into falling in love.
* In ''Anime/{{Vandread}}'', humanity has split into a planet of all males called Tarak and a planet of all females called Mejare. DNA from a couple is manipulated to give a new baby. On Tarak, this means a factory birth, while on Mejare, the baby is implanted in the womb to be born normally. This makes them effectively a pair of {{One Gender Race}}s, though normal breeding could be resumed. Note that these are not the only colony worlds left, just the main ones we see.
** It was later revealed to be due to an AncientConspiracy involving the mass organ-harvest of {{Expendable Clone}}s.
* ''Anime/MobileSuitGundamSEED'' derives much of its drama from the fact that DesignerBabies (Coordinators) exist alongside naturally-born humans (Naturals), leading to racial strife and outright warfare. Though the Coordinators still grow in a mothers womb and but are genetically modified shortly after conception (not before). The one true Designer Baby is [[spoiler:Kira, who was grown in a UterineReplicator and free of the influence of a mothers hormones during pregnancy thus the 'perfect' Coordinator]].
** The spinoff ''Manga/MobileSuitGundamSEEDAstray'' shows a darker side to this with Kaite Maddigan, a freelance mercenary who was abandoned by his parents because his mods didn't come out right. What's his problem, you ask? [[FelonyMisdemeanor His hair is two-toned (blond and black).]] It's implied that this is a common occurrence, since Kaite is a former member of a merc group made ''entirely'' of Coordinators who got discarded for similarly petty reasons.
** In X Astray, we are given Canard Pars. A failed attempt in the Perfect Coordinator project, but the only one besides [[spoiler: Kira Yamato]] to survive. At first, his entire reason for existence was to hunt down [[spoiler: Kira]] , and defeat him, to prove that he isn't a worthless, failed experiment.
* In ''Anime/MobileSuitGundamWing'', all of the Winner family's children [[spoiler:except Quatre]] were test tube babies, due to the then-current difficulties of natural birth in space.
** The story implies that the difficulties were slowly sorted out as mankind got acclimated to space, but because the Winner family had been in space the whole time they still had to deal with them.
* The Abh from ''LightNovel/CrestOfTheStars'' are all DesignerBabies. Most embryos are created in a lab, but some are created naturally and then later taken out and adjusted in a lab. These "love children" are seen as a beneficial and generally preferred way to reproduce.
* In the ([[SugarWiki/NeedsMoreLove relatively unknown]]) anime ''Anime/{{Himawari}}!'', most of the ninjas, [[spoiler: including the title character]], are test tube babies, designed to be perfect ninja.
* Ayanami Rei and Nagisa Kaworu from ''Anime/NeonGenesisEvangelion'' fit this trope, minus the whole metaphysical mumbo jumbo that accompanies them and their superpowers, of course. In the manga, Asuka Langley Soryu is one as well.
* It is quite heavily implied that [[spoiler:Aoi Hidaka, the main heroine]] of ''Anime/DancougarNova'', was born this way.
* In ''VideoGame/{{Utawarerumono}}'', it's eventually revealed that the various PettingZooPeople actually descend from a vast series of genetic experimentation projects that was undertaken in a hidden underground lab, apparently as part of a project to reclaim the (for some reason) uninhabitable Earth above. Their ancestors were all grown in the titular jars by the human scientists.
* In ''Anime/MagicalGirlLyricalNanohaStrikers'', Fate, Erio, Subaru, Vivio, [[spoiler:and Scaglietti himself]] are all the products of genetic engineering of one kind or another. The technology is experimental and illegal, but the children created by Project F and its descendants have full human rights.
* ''Anime/CaptainEarth'' has the aptly named Designer's Children, a group of children whose genetic structure was specifically altered so that other people could install their consciousness into them, effectively rendering these individuals immortal if the process is repeated. However, this genetic structure made them the perfect prey for the alien Kiltgangs, who installed ''their'' consciousnesses into them to infiltrate Earth and ultimately drain all of humanity's life force. The children know nothing of that and their Kiltgang personality is latent until they're awakened, but even unawakened, they possess supernatural abilities, called Singularities. Once they come in contact with another Kiltgang or libido, they awake.
* ''Manga/TokyoGhoul'': [[spoiler: The Sunlit Garden is revealed to be a facility that breeds HalfHumanHybrid TykeBombs for the CCG. These children are typically born nearly identical to their human parent, but possess the superhuman physical attributes of their ghoul parent. In exchange, however, they suffer from [[YourDaysAreNumbered a significantly shortened]] lifespan and begin to break down internally by the time they reach their 30s. This makes them ideal as disposable ChildSoldiers, trained from birth to fight and sent into the field as Ghoul Investigators around the age of 15. The mysterious Rize Kamishiro was also bred at the facility, and is stated to possess an unique and powerful kagune. The purpose of her creation hasn't been revealed]].
* ''Manga/OnePiece'': all children of [[spoiler:Vinsmoke Judge]] were genetically modified to be superhumans with near-limitless potential, in order to become perfect generals for his CloneArmy.

[[folder:Comic Books]]
* Franchise/{{Superman}}
** In Superman's ComicBook/PostCrisis origin, Kryptonians are born in a "birthing matrix". Jor-El attached a star drive to Kal-El's. This essentially allowed Superman to be "born" on Earth, which was coupled with a severe winter which isolated the Kent family farm for months; this allowed the Kents to claim he was their natural son and eliminated all the hassle adoption of a foundling would entail in the modern world. It also allowed for an alternate future storyline where Superman is elected President of the United States, which only people born in the United States can do. This has [[RetCon since been undone]].
** In ''Comicbook/KryptonNoMore'', Superman is made believe that his cousin Linda -alias Comicbook/{{Supergirl}}- and he have powers due to genetic modification.
* Marvel Comics' Thundra came from a future LadyLand {{Dystopia}} where babies are engineered in the "Temple of Genetics".
* A subtle example with Comicbook/{{X 23}}; when she decided an exact clone of Comicbook/{{Wolverine}} would be impractical, if not outright impossible, to make in the timeframe she was given, Dr. Sarah Kinney instead decided to duplicate his X chromosome and [[OppositeSexClone create a female instead]]. It's subtly implied that she also took measures to ensure that the clone would not only be positive for the X-gene, but that she would be born with the same mutation as Logan.[[note]]Mutant offspring of other mutants don't always share their parent's power set, IE Quicksilver vs. Comicbook/{{Magneto}}[[/note]] Considering Laura is {{The Ugly Guys Hot| Daughter}} OppositeSexClone, that she's generally depicted as having a genius-level intellect, one wonders what other sorts of modifications were made to ensure she was ideally suited for her purpose.
* In the ''ComicBook/SecretWars2015'' version of the ''ComicBook/NewXMen'' storyline "E is for Extinction", creating babies with the perfect X-Gene activated is something of a chic thing. However, it's not perfect - a baby born with one ability would end up with a completely different and unknown secondary mutation, so you could have a baby with hyper intelligence, yet end up as a bag of skin later on in life.

* Like in ''TabletopGame/CthulhuTech'', the first Nazzadi are this in ''FanFic/AeonEntelechyEvangelion''. Concerning the 'fic itself, unlike in the game, the Migou didn't stop making new Nazzadi after the mass defection, they just genetically made them better than the traitors and most importantly, absolutely loyal.
* ''Fanfic/FriendsOfASolarEmpire'' gives us [[spoiler: Twilight Sparkle]].
* ''Fanfic/TheChildOfLove'': Gendo made sure that [[spoiler:Asuka’s robot's cockpit was filled with a new type of LCL blended with especial DNA agents to alter Asuka’s baby.]] Due to this, Teri started to develop PsychicPowers before her birth.
* ''Fanfic/LastChildOfKrypton'': The exact method varies depending on the version (original story or redux), but Shinji was genetically altered with ''[[Franchise/{{Superman}} Kryptonian]]'' DNA before he was born. As a result he is, well, Superman.
* Done in ''Fanfic/{{Morphic}}'', since the author was specifically trying to go for a more [[{{Deconstruction}} realistic approach]] to Pokémorphs (which are often done as LEGOGenetics).
* In the ''Series/DoctorWho'' / ''Series/{{Firefly}}'' crossover "[[http://www.whofic.com/viewstory.php?sid=10564 Out of Joint]]", the Ninth Doctor posits that Simon and River were both given some genetic "adjustments" (more so in River's case).
* Both Serafina and Henriette in ''Fanfic/PanopticonQuest'' are these. They're also common in the Technocracy of ''TabletopGame/MageTheAscension'' in general.
* ''Fanfic/SOE2LoneHeirOfKrypton'': Asuka is born via artificial insemination from ''[[Franchise/{{Superman}} an unknown father]]''. She began to figure out what her genetic makeup had been tinkered with when she started bending titanium with her bare hands and seeing through walls.
* Deconstructed in ''Fanfic/ChildrenOfAnElderGod''. Since most people went mad or mutated horribly when they tried to control an [[HumongousMecha Evangelion]], NERV [[spoiler:created genetically mutated fetuses and implanted them in volunteers. One of them killed Asuka’s mother.]]
-->"How could you do something like that? That's horrible, going around altering the genetics of babies! How could you do that to my parents?"

[[folder:Films -- Animation]]
* FridgeLogic ([[FridgeBrilliance or brilliance]]) indicates that this is the case on board the ''Axiom'' in ''WesternAnimation/WallE''.

[[folder:Films -- Live-Action]]
* ''Film/DemolitionMan'': "Eeewww, disgusting! You mean... ''fluid transfer?''" It's not made implicit that babies are vat grown to be "better" than normal babies. It's rather heavily implied that sex is discouraged to avoid the spread of [=STDs=] that make AIDS look like a picnic. However, the world has become such a joyless "nanny state" that another highly plausible reason is SexIsEvil won to the degree that a less "naughty" way of having children had to be found.
** Presumably it was also a means of PopulationControl "abortion is illegal but so is pregnancy without a permit."
* In ''Film/{{Gattaca}}'', the former TropeNamer, gamete selection technology is routinely used to create the "best possible" child a pair of parents could potentially conceive. Naturally occurring conceptions are unusual, and the people born from them are regarded as inferior and suffer from discrimination, including insults such as "faithbirths", "de'''gene'''rates", and "godchild" (referring to their parents' decision to throw caution to the wind and trust in faith or God to give them a healthy child).
* ''Film/TheMatrix'': "Humans are no longer born. We are grown." However, the fact that people look the same inside and outside the matrix suggests that the sexual decisions made in the matrix are replicated in the real world by the machines.
* The scientists in ''Film/{{Twins}}'' were aiming to do this, but because their effort were done in the beginnings of genetic science [[GoneHorriblyWrong something went wrong]], the "perfectly engineered" gamete divided into two babies, who grew up to look like Danny De Vito and Arnold Schwarzenegger.
* In ''Film/ManOfSteel'', Kryptonians are [[BioAugmentation genetically engineered]] to fill different roles in their society. Kryptonian scientists Jor-El and Lara Lor-Van believe that the element of choice was lost in converting over to such a system, which, combined with the impending self-inflicted destruction of Krypton, led to their conceiving and birthing [[Franchise/{{Superman}} Kal-El]], the first naturally-born child in centuries.

* Heinlein's ''Literature/BeyondThisHorizon'' from 1942 has the same gamete-selection process and discrimination as in ''Film/{{Gattaca}}''.
* OlderThanTelevision: ''Literature/BraveNewWorld'' by Aldous Huxley. Babies are "grown" here (and "decanted" rather than "born"), though this was before the development of modern genetics, so they must resort to more complicated and organic means than flipping genetic switches to create their hereditary castes, such as [[OneDrinkWillKillTheBaby alcohol]].
* {{Utopia}} Example: ''Herland'', by Charlotte Perkins Gilman. The titular land is a [[MarySuetopia utopia]] because it is inhabited ''only'' by women, who can reproduce parthenogenically (without a male), and without genetic diversity/contamination, only pass amiable, peaceful, and otherwise perfect personality genes onto their offspring.
** Though it's really more an example of eugenics than designer babies. Women who are considered a danger to society are not allowed to breed.
* Another 'utopian' example, is the city of Diaspar, the last bastion of humanity, in Arthur C. Clarke's ''Against the Fall of Night''[=/=]''Literature/TheCityAndTheStars'', where humanity appears to have given up on sexual reproduction, in favour of an unimaginably massive database of personalities. Whenever a new person is to be born, a personality is downloaded into a created body, and assigned a couple to be its parents. When a person dies, they may choose what memories of theirs will be carried into their next incarnation, which may be ''millennia'' in the future, such is the size of the database, and those memories will become available to their new incarnation once it becomes an adult and has developed a truly unique personality through its childhood. 'Uniques', personalities seemingly generated during the creation process, do occur, but are viewed either as a wonderful accident, one of many little tricks to prevent stagnation, or as some great and possibly subversive plan by Diaspar's architects. Of course, [[spoiler:later on it turns out that there is a second remaining pocket of humanity, Lys, where humans have chosen to be born naturally, and die without the assurance of artificial reincarnation, living an Agrarian lifestyle and having over time developed empathic capabilities. Interestingly however, neither is presented as 'right', rather, as two distinct, viable versions of utopia. The part the book presents as ''wrong'' is the two cultures decision to totally isolate themselves from one another.]]
* In ''Literature/WomanOnTheEdgeOfTime'', this is how the MarySuetopia society reproduces. It's all but stated that this is a necessary sacrifice to eliminate the last vestige of gender discrimination. On the upside, a child is not only raised by the whole village, but get three parents to look after and nurture it. The society also tends to be a FreeLoveFuture.
* In Creator/LoisMcMasterBujold's Literature/VorkosiganSaga, the Cetagandan Haut-lords in the Vorkosiverse reproduce entirely without sex or even coupling being involved... every child is created through contracts arranged by high-ranking family members, frequently with positive genetic alterations added, then the baby cooked up in a replicator and handed to the appropriate parent. The Haut are practically considered a superhuman sub-race at this point.
* The ''[[Franchise/StarWarsExpandedUniverse Star Wars]]'' [[Franchise/StarWarsExpandedUniverse Expanded Universe]] gives us the Khommites, who believed their society was perfect, and froze it by cloning themselves for a thousand years. This changed when the 81st clone of Dorsk was found to be Force-sensitive and left to become a Jedi, eventually bringing Khomm into the galactic war they had avoided up to that point due to their planet's isolation and lack of resources that anybody else cared about.
** The Bith, a species known for intelligence as well as musical prowess, are unable to breed naturally and breed by using a machine that combines the DNA of the two parent Bith in order to create an embryo.
* Most denizens of the [[Literature/TheCulture Culture]] are designer babies. Except that most of the genetic modifications are made to increase lifespan, and to give them [[AuthorAppeal longer and stronger orgasms]] and the ability to naturally [[ImmuneToDrugs synthetize and use drugs with no ill effects]].
* In ''Franchise/{{Dune}}'', the Tleilaxu are a race of humans whose [[PlanetOfHats hat]] is GeneticEngineering - their stock in trade is custom-designed organics. People, animals, living furniture; you name it, they'll make it. This is held in stark contrast with the rest of Galactic society where all breeding is strictly natural by taboo. The Tleilaxu are therefore tolerated for their usefulness but are considered disgusting and degraded by most people. It gets even worse in the sequels when it's revealed exactly what the "[[UterineReplicator axolotl tanks]]" they use to grow their products are.
** Even the Bene Gesserit, an all-female group obsessed with breeding programs, will only use natural methods of impregnation, to the point of forcing the openly-gay Baron Harkonnen to have sex with one of them. This gets ludicrous when they're worried that bloodlines may die out when all they'd have to do is obtain sperm samples and keep those in nullentropy capsules to use in worst-case scenarios. These women claim to be entirely rational (they despise love because it clouds reasoning) but refuse to break irrational taboos. In fact, the only time this is broken is by one of them who does it ''out of love''. Tessia offers to impregnate herself with Rhombur Vernius's half-brother's preserved semen, as Rhombur himself is unable to have children.
** The Bene Gesserit are shown to have a horror of artificial insemination in ''Literature/DuneMessiah'' less out of ethics than because using sex to control powerful men is ''at least'' as important as having their babies.
* In a number of stories by Isaac Asimov, Spacers try to reproduce this way, only to find the fetus only takes fully and grows when conceived the old-fashioned way.
* Parodied in ''Mallworld'', where human babies are produced to order by birth factories ... not because it's necessary or mandated by the state, but because designer babies are ''trendy''.
* In Laura Mixon's ''Burning the Ice'', all of the colonists are clones grown in vitro. Each colonist is a member of a pair of clone twins or triplets, which also belongs to a family of clone siblings of various ages. The protagonist, Manda, is unusual in that she's a singleton, though she does have older clone siblings of the [=CarliPablo=] group.
* Partial example, in ''Literature/TheDarkswordTrilogy'', sex is banned and impregnation must take place magically.
* In ''The Court of the Air'', female slaves in Cassarabia ''wish'' their wombs were used to incubate this trope, and not the monstrous MixAndMatchCritters which the local bio-wizards dream up.
* In Creator/SMStirling's [[Literature/TheDraka Domination of the Draka]] series, the Draka, starting in the late 20th Century, gene-engineer their own babies for physical strength, speed and endurance, their serfs' babies for docility, all babies for intelligence. By the 25th Century humanity in the solar system has split into two distinct species, which by design are not interfertile: ''Homo drakensis'' and ''Homo servus.'' The ''drakensis'' are designed for war and survival, almost impossible to kill, do not age physically after the age of 25, and exude pheromones they can use to emotionally dominate ''servus'' and unmodified ''Homo sapiens.'' (They're also constantly horny, incredibly sexy, and universally bisexual.) A Draka female, ordinarily sterile, is still capable of bearing their own babies, if she takes a month to get her uterus up and running by biofeedback techiques, but it is considered perverse; all ''drakensis'' are gestated by implanting fertilized ova into ''servus'' host-mothers, or mechanical "orthowombs."
* In ''The Fifth Sacred Thing,'' by Starhawk, post-eco-apocalypse southern California is ruled by a high-tech religious dictatorship with several genetically engineered slave-castes -- some bred for war, some for sexual recreation.
* In the Literature/HumanxCommonwealth universe, the outlawed {{Evilutionary Biologist}}s known as the Meliorare Society used this method to produce their "test subjects", including the series' primary protagonist, Flinx.
* The inhabitants of Sulva (Earth's Moon) are said to be born this way in ''Literature/ThatHideousStrength''. Apparently they can only be turned on by {{sexbot}}s and therefore can't make babies the normal way.
* In Creator/RobertAHeinlein's novel ''Literature/{{Friday}}'', human society has learned to grow custom-tailored humans and other creatures; these are known as "Artificial Persons" if they are superficially human and "Living Artifacts" if they are clearly not human. Both are subject to a great deal of FantasticRacism; the eponymous protagonist is an AP and suffers from a crushing inferiority neurosis because of it.
* In Creator/SergeyLukyanenko's ''Literature/{{Genome}}'', many parents choose to "specialize" their children before they're born, if they can afford it. The children grow up normal, but at puberty their bodies and minds undergo changes that irreversibly determine their life path. Furthermore, they don't care because every Spesh loves his or her job. They're programmed to love it. These modifications range from enhanced logical reasoning for detectives to extra joints for fighters, not to mention enhanced reflexes and strength. Also, starship pilots, detectives, and tax inspectors are incapable of love, as it clouds judgment. On the other hand, hetaeras (call girls) are conditioned to fall in love with their clients and be unable to fall out of love until their client reciprocates. There is plenty of distrust between the Speshs and the Naturals, even though everyone has some sort of gene therapy done on them as a fetus, like corrected eyesight and fixed genetic defects. Some jobs simply cannot be done by Naturals, like power specialist who are genetically-modified to handle high doses of radiation (shield it mostly with their skin and long hair).
** Interestingly, at least one job that is assumed to be Spesh-only can be done by an extremely-skilled Natural. This is shown in the novel where a Natural becomes a starship navigator, a job that requires one to memorize the multidimensional map of the galaxy and be able to plot a safe and fast course through FTL. He turns out to be a pretty good navigator, despite his preference for wearing skirts (not [[InsistentTerminology kilts]]).
** The protagonist mentions that, by law, every Spec has a right to remove his or her specialization. However, in practice, this never happens. For one, each Spesh loves his or her job. And two, many changes are simply irreversible.
* In another of Lukyanenko's series called ''Literature/LineOfDelirium'', the protagonist Kay Dutch turns out to be a genetically-engineered "super". His very existence is in danger if this knowledge becomes public, as genetic engineering is against the Imperial law. He is stronger, faster, and smarter than most humans with an affinity for languages (even alien languages). He mostly uses his abilities for mercenary work. His "test tube sister" Lyka Seiker's abilities are more focused on mental calculations, allowing her to rapidly become the leader of an interstellar crime syndicate.
* In ''Literature/HonorHarrington'', Manpower, Inc. specializes in these. Everything from technicians to miners to jugglers and ''entertainers''. Skrags in the backstory are a mix of Designer Baby and {{Transhuman}}, with the nastiest containing so many artificial improvements they were sterile and long dead. Many characters are actually somewhat 'Genie' as Honor herself. But due to the horror of the Skrags, anything Transhuman is looked down on. The new Arc is a war between Transhumanists and baselines that started as a break in philosophy.
** There are essentially two (or possibly three, depending on how you count) kinds of DesignerBaby. First, there are genetic slaves, Manpower Inc's product. These are humans who have been genetically engineered (and psychologically conditioned) to specialize in some specific service, usually at the cost of having all kinds of other health disorders (for example, slaves designed for heavy labor are both grotesquely over-muscled and have more efficient muscle fibers, but at the cost of a much-increased appetite and a high chance of kidney and liver failure). Then you have the Mesan Alignment, the end-product of millennia of genetic engineering and selective breeding aimed at producing humans who are better at everything than baseline humans. Finally, you have what might be described as minor genies, human bloodlines who have experienced very low-scale genetic modification, usually to allow settling worlds that would otherwise have too high a gravity or too little oxygen or whatever.
* In ''Literature/InfinityBeach'', genetic engineering is common. The main character, Kimberly, is a clone of her older sister Emily.
* In Creator/KevinJAnderson's ''Literature/{{Blindfold}}'', the Truthsayers are a group of genetically-engineered people trained from birth with the use of the [[MeaningfulName Veritas]] drug, which temporarily increases their brains' receptive abilities, allowing them to detect another brain's EM impulses (i.e. [[PsychicPowers read thoughts]]). While it is possible for a normal person to use the drug, the results are unpredictable. There is also the fact that it is a gross violation of privacy. Since the Truthsayers have no familial or genetic ties to anyone outside their group, they are used as {{Living Lie Detector}}s. Their verdict in court cases is final. However, not all trainees become Truthsayers, meaning the genetically-engineered process is not perfect.
* Creator/SLViehl's ''Literature/{{Stardoc}}'' series follows a young female doctor named Cherijo Torin, who discovers in the first novel that she is a genetically-modified clone of her "father", who eventually wanted to marry her. That's right, not only did he want to [[ScrewYourself screw himself]] (and later novels indicate that he already did that with his ''male'' clones) but he wanted to do it with someone he raised as his daughter. Cherijo (who name is, actually, an acronym meaning [[FunWithAcronyms "Comprehensive Human Enhancement Research ID: J Organism"]]) discovers that she is immune to any disease, as her body actively fights against any foreign organism in her (which causes problems when she [[spoiler:gets pregnant]]), and has a HealingFactor (in a later novel, she is perfectly willing to throw herself from a big height in order to get a winged friend to save her, even though her colleague later points out that, while her body would probably heal, any brain damage would be permanent).
** Oh, and genetic engineering is forbidden in human space ([[spoiler:except by her "father", who has helped to pass the law and received special dispensation]]), and any "freak" is to be caught and executed as a [[WhatMeasureIsANonHuman non-person]]. When the colony finds out that she is a clone, some of the JerkAss characters immediately start calling her "it", claiming that her "intelligence" is merely an imitation programmed into her.
* ''Literature/MySistersKeeper'' features an extremely mild version of this. Anna was genetically engineered to be an exact donor match for her cancer-stricken older sister Kate. The main plot of the book is Anna suing her parents to escape having to donate a kidney to Kate.
* C.J. Cherryh's ''Literature/AllianceUnion'' universe has the Union using genetically engineered "azi" to rapidly increase their population, azi are separated into castes designated by Greek letters (with alphas being geniuses) but the differences in intelligence don't necessarily breed true when they are freed and have children.
** In fact, Resune's Azi program is a bit more complete than just Designer Babies. It's revealed in ''Literature/{{Cyteen}}'' that Resune doesn't merely design babies, but the entire population to ensure a healthy mix of genetics [[spoiler:and bias the populations towards Resune's political aims]].
* Basically the premise of ''Literature/{{Replica}}''.
* In ''Literature/CourtshipRite'', some clans do perform genetic manipulation to try to improve themselves, but since the results can be unpredictable, and the techniques are expensive and difficult, it's not all that common. Genetic screening for undesirable traits is common, but even there, the Getans are aware that diversity is a boon in the long run.
%% * In ''Literature/MaximumRide'', the entire flock is this. They're regular kids fused with bird DNA.
* Everyone in ''Literature/{{Skinned}}'' is like this. One couple is considered the futuristic version of hippies because they chose to conceive naturally. While there's nothing wrong with their son, he's quite physically flawed when compared to everyone else (for instance, he's basically the only person in the city who wears glasses because he needs them, [[PurelyAestheticGlasses not because they look cool]]).
* Francine in Creator/{{Justina Robson}}'s ''Living Next Door to the God of Love'' - in the novel's near(ish)-future setting, this seems to be a fairly unremarkable choice for moderately affluent parents, and the designer children are known as "Genies". Francine's mother chose various traits for her, including high intelligence, athletic physique and amber-blonde hair. However, Francine clearly doesn't think she's anything special (perhaps by Genie standards, she isn't) and has something of an inferiority complex.
* [[Literature/DrFranklinsIsland Doctor Franklin]]'s dream is to create useful animal-human hybrids. When this trope comes up he sneers and claims that starting from a scratch just won't do for what he wants.
* Nicolae Carpathia, the {{Antichrist}} of the Literature/LeftBehind series, was a designer baby of a project funded by Jonathan Stonagal, with his genetic makeup being the hybrid sperm of two intelligent men (both of whom were gay) impregnated into a willing host, Marilena Carpathia. Of course, Jesus in ''Glorious Appearing'' reveals that it is God who gave Nicolae the gifts of beauty, wisdom, intelligence, and personality, dismissing the idea that it all came from science.
* In the Literature/MoreauSeries, the U.N. forbids human genetic engineering. Several countries did so anyway, results are called frankensteins. [[FantasticRacism They aren't popular]].
* The ''Literature/{{Idlewild}}'' series has the Ten and their children, Waterbabies. Both generations are engineered with the single purpose of surviving [[ThePlague Black Ep]].
* "[[MixAndMatchMan Tetraparentals]]" in Vonda [=McIntyre=]'s novella ''Screwtop''.
* In the ''Literature/ZacharyNixonJohnson'' series, the Thompson Quads are four girls who were designed by Dr. Thompson to be superhumanly beautiful, intelligent, and powerful.

[[folder:Live-Action TV]]
* In two-part crossover of ''Series/LawAndOrderSpecialVictimsUnit'' and ''Series/LawAndOrder'', the cast(s) encounters a character played by Estella Warren who was conceived as a genetically superior {{Transhuman}} by her scientist father. As an adult, she became a con artist who date-raped handsome and talented men in order to continue her father's work. (One character in ''SVU'' even mentions this trope by name.)
** A latter-season episode of ''Law & Order'' had a perp whose main motivation was preventing the "gay gene" from being discovered, which he believed would lead to the elimination of all future gay people in the womb.
* In ''Series/BlakesSeven'', crewmember Cally is from Auron, a world where parents clone themselves to create their children. Auron had only started to do it several decades previously, so there were also people who were 'born of natural birth'. Cally herself had a twin sister Zelda.
* In ''Series/CenturyCity'', a fertility specialist is sued for having his clients babies turn out gay.
* In the ''Series/DoctorWho'' episode "The Doctor's Daughter", [[spoiler:there's an entire society created by machines which spilt one persons cells into a sets of haploid cells and recombines them to make a new adult in seconds.]]
** The Time Lords as well if you consider TheExpandedUniverse Canon. It reveals that Time Lords have been inflicted a species-wide Infertility curse by magical Queen who was overthrown by Rassilon. So the Time Lords avoided extinction with by using this, even when the curse wears off. Mind you its not like they can have sex, its because that they have been using this trope for so long they decided to avoid the whole pregnancy process when you can get an instant baby.
** Ridiculously, the reason for this is because the Doctor's CelibateHero status is something fans and some writers had already become very protective of by TheEighties - but he's got a granddaughter. There were even plans to reveal Susan as not his biological granddaughter ''onscreen,'' simply a girl he'd rescued as a child who ''called'' him Grandpa or something like that, but Carole Ann Ford said she'd not return for "The Fifth Doctors" unless she ''was'' still his granddaughter. The whole "'looming' babies" thing is all so the Doctor can be said to have never done what most of us must do to have children and therefore grandchildren.
* In one episode of ''PicketFences'', it's discovered that a reproductive services clinic is gestating human babies inside of cows. One infertile woman who has contracted for her child to be grown this way says that this is done to bypass the legal minefields associated with hiring a human surrogate mother. ("I own the cow!") Subverted in that nothing is said about selecting for superior genetic traits, and the use of cows as surrogates is voluntary on the part of the parents, albeit done in secret to avoid controversy.
* Ransik's villain motivation in ''Series/PowerRangersTimeForce'' is that, in the year 3000, where all are perfect designer babies, the process sometimes goes wrong and he was born a [[{{Mutants}} mutant]], and was a pariah growing up, ending up living on the street. In fact, all of the [[MonsterOfTheWeek Monsters of the Week]] are mutant accidents.
* ''Series/SpaceAboveAndBeyond'' had "Tanks", vat-grown, genetically selected humans made to fill a worldwide labor shortage after a partial DepopulationBomb, and then abandoned when no longer needed. Naturally, they are the target of [[FantasticRacism prejudice and stereotype]].
* In the ''Franchise/StarTrek'' franchise, Earth suffers a terrible series of Eugenics Wars in the [[TwentyMinutesIntoTheFuture near future]] between normal humans and genetic "augments." By the logic that "superior ability breeds superior ambition," these young [[{{Ubermensch}} Ubermenschen]] all tend to suffer a [[TakeOverTheWorld Napoleon complex,]] leading them to war not just with mankind, but with each other. Humanity wins, with the lasting result that [[NoTranshumanismAllowed genetic engineering of human beings is outlawed and held in universal contempt for centuries afterward.]] The two most well known augments in Trek are Kirk's archnemesis Khan Noonien Singh; and ''[[Series/StarTrekDeepSpaceNine Deep Space Nine]]'''s doctor Julian Bashir, who was augmented illegally.
** Apparently genetic resequencing is allowed for medical purposes such as preventing birth defects, but forbidden for "cosmetic" or "augmenting" reasons. In the ''Series/StarTrekVoyager'' episode "Lineage" The Doctor uses resequencing to eliminate a spinal defect in B'Elanna's child, but balks at making changes to eliminate or suppress the child's Klingon DNA.
* Played with a lot on ''Series/TheXFiles''. There are many attempts to make a human/alien hybrid. Most notable was Emily, Scully's [[spoiler: daughter]], who ends up dying soon after she meets her. And though many attemps are made, nothing sticks. All the hybrids die. This becomes a problem when Scully conceives William, who is what everyone involved in the conspiracy has been after--a human alien hybrid gestated naturally. And why the hype? After realizing that their deal with the aliens has gone south and [[spoiler: the world will be taken over by an alien virus in 2012]], the good guys seek to use William to find a way to stop that from happening. The bad guys want to stop the good guys. Which equals ''many'' near-death experiences for itty bitty William.
* In ''Series/{{Helix}}'' ResearchInc, Arctic Biosystems' lab rats are genetically engineered to lack sex organs, which, according to its head of security, makes them more controllable.
* In ''Series/AlmostHuman'', the so-called "Chromes" are genetically-engineered to have perfect health and above-average intelligence. One of the main characters is a Chrome, which is unusual as Chromes never go into police work, thinking of it as a waste of their talents. Chromes have a lot of influence, as a number of politicians and judges are Chromes. One episode involves a Chrome dying of what appears to be a heart attack. This threatens to start a panic, as Chromes are not supposed to be susceptible to such things.
* ''Series/TotalRecall2070'': In one episode, the Citizen's Protection Bureau is taken over by a mysterious hacker who turns out to be the result of a failed human gene modification experiment. Rather than creating the perfect {{Transhuman}}, it ended up creating intelligent children with severe psychological disabilities.

* ''InTheYear2525''.
-->Won't need no husbands, won't need no wives
-->Pick your sons, pick your daughters too
-->From the bottom of a long black tube
* "Betty and Me" by Music/JonathanCoulton features the viewpoint character looking forward to a new baby made "out of DNA" to be "better than me", with the help of Dr. Martin. [[spoiler:It's a subversion--he only ''thinks'' this trope is what's happening; by the final verse it's clear that his wife Betty is cheating with "Dr. Martin".]]

[[folder: Newspaper Comics]]
* Parodied in ''ComicStrip/CalvinAndHobbes'', when Calvin asked his dad where babies come from and was told that hopeful parents just buy a kit from Sears and assemble them. Calvin, on the other hand, was a marked-down knock-off brand from K-Mart. This is yet another lie Calvin's dad says to torment his son.

[[folder:Tabletop Games]]
* In ''Tabletopgame/BattleTech'', the "trueborn" warriors of the Clans are an entire [[FantasticCasteSystem caste]] of [[SuperSoldier super soldiers]] who are created this way, descendants of the 600 loyalists who served Nicolai Kerensky after the Star League Defense Force exodus - led by his father - collapsed into anarchy. Only those who have proven themselves in battle have the honor of having their "genetic legacy" preserved in the breeding program; between this and being raised in TheSpartanWay, perhaps only one trueborn in a hundred actually has any descendants (at least in the warrior caste itself), especially since they are considered to be over the hill at 35 - those over 35 are given just an outdated rifle and used as CannonFodder. However, the effectiveness of the program outside of their enormous "Elemental" PoweredArmor soldiers is debatable, as physical strength means little in the cockpit of a [[HumongousMecha BattleMech]] or [[SpacePlane Aerospace Fighter]]. In fact, their aircraft pilots are [[MugglesDoItBetter noticeably worse than their normal counterparts]] in the Inner Sphere.
* ''TabletopGame/{{Paranoia}}'', in which everyone's a clone. Six times over, in fact.
** Well, sort of... some times. In early editions there were clone families of six that were decanted and raised in the same environment, and treated more or less as one person. This did not make sense (not that Alpha Complex ever does), as we're left wondering where the other 5 are most of the time (it was occasionally addressed, but mostly just left off-camera). Later editions have it so every citizen is, theoretically, cloned when they die (except traitors that have earned an erasure), but the red tape delays it to the point of never happening, but Troubleshooters have six immediate backups because they are in highly lethal situations, but with important missions that must be completed. Higher ups tend to buy more packs of six clones when needed, and Ultraviolets are so important the Computer gives them an essentially infinite number of quick clones. This still doesn't make sense, but in a way that works.
* The Primarchs of ''TabletopGame/{{Warhammer 40000}}'' fit into this mold. The God Emperor created each of the 20 Primarchs, using his own DNA, to embody a portion of himself. The Space Marines are implanted with organs cultured from the Primarchs tissues, and recruits are picked at age 10 or above.
** The Tau practice this trope on a racial level: Parents are preselected based their genetic qualities, mate, and then their child is sent to the education center for indoctrination. The parents take no part in raising it, but some take an interest in their progress.
** The Lamenters chapter of SpaceMarines are descended from the Blood Angels who managed to more or less eradicate the [[LeeroyJenkins Black Rage]] that plagues their parent chapter thanks to genetic manipulation. Unfortunately, this comes at the cost of suffering FromBadToWorse at every opportunity: getting caught in a Warp storm after a bloody siege, being branded traitors due to a misunderstanding, losing two thirds of their chapter due to said misunderstanding and sent on a crusade as penitence, running into hive fleet Kraken on said crusade...
** {{Inverted|Trope}}: Most of the Dark Eldar are grown ''en masse'' in PeopleJars. "Trueborn" children, who are born via the natural breeding process, are a luxury afforded only to the upper class.
* Nearly everyone in ''TabletopGame/TranshumanSpace'' (at least in the Fifth Wave) is at the very least "genefixed"; no genetic disorders. There are also parahumans, who range from "like humans, only better" (in theory; some of them grow up to have serious personality problems) to genetically-altered humans for different environments, such as Mars or the deep ocean.
* In ''TabletopGame/RocketAge'' the Nazis are breeding perfect Aryans for their army on Mercury.
* Zig-zagged in ''TabletopGame/HcSvntDracones'', most of the population are genetically-engineered human-animal hybrids known as Vectors that were created shortly before humanity wiped itself out in a nuclear war. But they've been breeding naturally for centuries at the time of the game setting. It is possible to design a custom child that doesn't resemble any established Vector species, but it's illegal to make them any stronger or smarter or have special abilities that unaugmented Vectors lack.
* In ''Tabletopgame/ArsMagica'', A character who researches and recovers an ancient fertility magic tradition will be able to create rituals to endow unborn children with nearly any virtue or flaw.

* Discussed in the song "Oh, Happy Day" from the musical ''Li'l Abner''.

[[folder:Video Games]]
* An old DOS game called ''VideoGame/GenderWars'' plays off this trope - in the game world, human males and females are embroiled in a literal battle of the sexes, each intent on exterminating the other. Because traditional reproduction is effectively banned, each side uses artificial means of conception and incubation to maintain their populations. The twist, of course, is that neither side possesses the means to reproduce without "help" from the other; the males routinely attack female storage facilities to steal frozen eggs, while the females do the same to male bases to obtain sperm samples.
* ''[[VideoGame/AdvancedVariableGeo Advanced V.G.]]'': For reasons unknown, [[BigBad Miranda]] [[CorruptCorporateExecutive Jahana]] is determined to create [[{{Tykebomb}} the ultimate fighting machine.]] So she founded [[ResearchInc Section-9]] as her top-secret R&D department, where she began by experimenting on her own daughter, [[SuperPrototype Reimi.]] And also successfully created K-1 and K-2. All three were defeated by [[TheProtagonist Yuka]] [[SpiritedCompetitor Takeuchi]], who then became [[ArchEnemy the focal point]] [[ItsPersonal of Miranda's hatred.]] After disposing of the K units, she created [[http://www.youtube.com/watch?v=WhMfp-jADZY the Material Twins]] as her revenge.
* In ''VideoGame/{{Prototype}}'' Hunters, a GiantMook superhuman mutant, are grown from normal humans by being stuffed into sacs or water towers flooded with [[TheVirus the Blacklight virus]]. Hunters do not screw, they'd rather fight.
* Miranda Lawson from ''VideoGame/MassEffect2'' is one of these. Her father is wealthy and influential man, thus his desire to create a genetically-modified specimen, a daughter with superhuman abilities, intelligence, and, ahem [[IncrediblyLamePun "talented"]] in every way. [[spoiler:The same goes for her twin sister as well.]]
** It seems that Daddy may have [[spoiler:put in some "[[{{DRM}} Fabrication Rights Management]]" into Miranda, as the dossier on her that the Shadow Broker has indicates she may be infertile.]] Wonderful guy, her dad.
*** If so, he did it by a probably rather painful means: [[spoiler: noncancerous tumors have wrecked her reproductive system.]] Again, no wonder she hates him.
** Grunt is another example, designed to be a SuperSoldier even by [[ProudWarriorRaceGuy krogan]] standards. Thanks to NeuralImplanting, he's "born" with the body and vocabulary of a young adult but no sense of place or direction (enter the player character...).
** '''Humanity''' as a whole is moving towards this. By the twenty-second century, genetic engineering has advanced to the point where the [[WeWillHavePerfectHealthInTheFuture majority of genetic disorders have been cured]]. Governments provide free screening and genetic modification to prospective parents, and as a result everything from near-sightedness to cystic fibrosis has been cured. While IVF is the preferred method of modification, it can also be done on embryos and newborns out of respect for personal belief.
* The Sivadians in ''VideoGame/{{Otherspace}}'' have taken genetic modification in two directions. First, to create beautiful, intelligent, athletic offspring. Second, to create specialized slaves, designed to be [[{{Wolverine}} the best there is at what they do]] to better serve their masters.
* The term has become a running joke among players of ''VideoGame/FireEmblemAwakening'', as you can optimize the parent characters' marriages to make the future kids into {{Game Breaker}}s. It turns out that in-story, [[spoiler: The Avatar is one of these, specifically bred to be a perfect vessel for Grima.]]
* Milluim is implied to be this in ''VideoGame/TheLegendOfHeroesTrailsOfColdSteel''. In one of her bonding events in the sequel, she mentions that she has siblings, but no parents. (And a member of the QuirkyMinibossSquad shares her surname and has the same fighting style) She has difficulty even comprehending the concept of crying. She's a surprisingly effective spy despite her extreme eccentricity. Claire, who has ties to the Intelligence Division, knows more about her origins but isn't at liberty to talk about it. Said QuirkyMinibossSquad member is only able to give one hint as to their origins: "Black Workshop".
* [[spoiler:Most of the main cast]] in ''VideoGame/ShinMegamiTenseiII'', created by the Archangels in a hilariously misguided attempt to fulfill their duties. Whatever the path chosen, they ''never'' get what they expect.

[[folder:Web Original]]
* The superiors, tweaks, splices/rianths and most nearbaselines in ''WebOriginal/OrionsArm'' were created through generations of germline genetic engineering. Since it's been going on for thousands of years now, it's regarded as normal and no one has any problem with it - indeed, almost no true completely unmodified baseline humans are around any more.
* All Coalition (Ourkind) soldiers are created this way in ''Literature/UnlikelyEden''.
* [[http://www.futuretimeline.net/ FutureTimeline.net]]. Possible by [[http://www.futuretimeline.net/21stcentury/2050-2059.htm#designer-babies 2053]]. They even use the trope name.

[[folder:Web Comics]]
* Dr. Bunnigus from ''Webcomic/SchlockMercenary'' was a Designer Baby as the result of eugenic laws; her inbred and mentally limited parents were required to improve their child, so they gave her a genius IQ and a stripper's body. Her first name, [[TomboyishName Edward]], is because the parents read "E.D." on her genetic profile (for Exotic Dancer) and thought Ed was her proposed name; wanting to show class, they went with the full name "Edward" instead. What's more, she's black (or some brownish ethnicity), and they're both white hillbillies, so apparently their many social problems did not include racism.
* In ''{{Webcomic/Homestuck}}'', [[spoiler: All four kids are revealed to be these, John and Jade being made from Grandpa's and Nana's combined DNA, and Rose and Dave being made from Mom's and Bro's. According to the trolls, anyone who's destined to play Sburb is created in this manner.]]
** In the same sequence, it's revealed that [[spoiler:the Guardians (Grandpa, Nana, Mom, and Bro) are all clones ''of themselves''. It's not clear from what, if any, source the genetic material of the kids destined to play the game comes, but it seems to some degree to be tailored to success at Sburb.]]
* [[Webcomic/{{Freefall}} Winston Thurmad]] was born to well-meaning parents who were convinced that humanity was going to be living exclusively in space by the time he grew up, so they splurged on all manner of genetic modifications optimized for life in zero-G. Most of them are internal modifications to protect against various forms of atrophy and otherwise optimize him for life on a spacecraft, but he can't grow hair either.
* WordOfGod explanation for Rhonda in ''Webcomic/UmlautHouse 2'', who has [[HomosexualReproduction two biological fathers]]. A throwaway line by her grandmother towards the end of the first series implied that this is fairly common in their era.
* In ''Webcomic/GenocideMan'' most types of "genetic deviant" are made this way. Such as the [[http://www.genocideman.com/?p=63 Ugandan Deviants]] who were the result of witch doctors "blessing" pregnant mothers with a teratogenic virus.
* ''WebComic/StandStillStaySilent'' has a proto-example in the Dagrenning program. Set up by the Icelandic government to ensure population growth, genetic diversity and immunity to TheVirus, the program consists of a number of sperm and/or ova banks which only take material from immune donors, from which anyone who wishes to concieve a child can draw freely.

[[folder:Western Animation]]
* ''WesternAnimation/ExoSquad'' has an interesting reversal. While humans are born naturally, the Genetically-engineered Neosapiens are artificially grown by the "brood." At the end of the series, one of the Neosapiens, Marsala, lobbies with the government to allow the creation of one final brood that's capable of natural breeding.
* ''WesternAnimation/BatmanBeyond'' has Xander, whom the terrorist organization Kobra created in a UterineReplicator and raised so they could have a perfect leader.

[[folder:Real Life]]
* Designer Calves, Designer Chicks, Designer Pullets, Designer Lambs: this trope is ubiquitous in the livestock industry.
** And in the seed industry. Designer Corn, Designer Cotton, Designer [[http://en.wikipedia.org/wiki/Brassica_napus Rapeseeds,]] and especially Designer Soybeans.
* [[http://en.wikipedia.org/wiki/Preimplantation_genetic_diagnosis#Indications_and_applications Already here for humans, in some cases]] - mostly to prevent horrific, fatal genetic diseases such as Cystic Fibrosis.
* [[http://en.wikipedia.org/wiki/Artificial_uterus More could happen.]]
* At present, is illegal in many countries.
** Anything of the sort would require a great deal of testing, which could be morally dubious as it would by its very nature be human experimentation, and the creation of human beings for experimental purposes.
** There are also concerns about common vulnerability to disease with genetically engineered crops and people, due to their higher degree of genetic similarity to one another.