"American Gothic" may refer to:

* ''Series/{{American Gothic|1995}}'', the 1995 series.
* ''Series/{{American Gothic|2016}}'', the 2016 series.
* ''ComicBook/AmericanGothic'', the ComicBook/TwoThousandAD strip.
* AmericanGothicCouple, Grant Wood's much-imitated painting.

For Gothic fiction in general, even if set in America, see GothicHorror.

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