Dedicated to villains who have completely lost it.
- Bleach:
- His words say it all.◊
- Also Aizen went from this◊ to this◊ after a long fight.
- Death Note: Light Yagami as his plans come to ruins, and he demands Matsuda to defend him.
- Dragon Ball Z:
- Frieza starts off as "I have an empire and no one can beat me"◊. Cue to Super Saiyan Goku's fight finale... no more empire, and beaten by a monkey.◊
- Cell before◊ fighting Super Saiyan 2 Gohan after◊ fighting Super Saiyan 2 Gohan.
- The Misfit of Demon King Academy: Emilia Before◊ and during◊ the stages◊ of her breakdown, which continued into her half-demon◊ transformation.
- Return to Oz: The Nome King goes from this◊ to this◊ once he realizes what Dorothy is doing.
- Sonic the Hedgehog (Archie Comics): Dr. Eggman before,◊ during◊ and after◊ his descent into madness.
- Avatar: The Last Airbender: Princess Azula◊ starts out as a The Chessmaster. The finale gives us her complete◊ descent◊ into◊ madness◊. Also overlaps with Sanity Slippage.
- Ratigan from The Great Mouse Detective Going from this◊ to THIS◊ after being Out-Gambitted.