While the ''VideoGame/{{Touhou}}'' fandom generally operates under the EveryoneIsGay format, the games themselves (and especially the [[ExpandedUniverse supplementary]] [[AllThereInTheManual material]]) don't exactly dispel the notions:
* Reimu gets this a lot. Although treated warily at best by most humans, amongst youkai, she's absurdly popular. They're almost instinctively drawn to her, despite Reimu not feeling strongly one way or the other about youkai [[PretendPrejudice even though hunting youkai is her job]], which is implied to be ''why'' they're drawn to her. They almost always want to gather at her shrine for drinks and revelry; Remilia in particular goes periodically to the shrine just for taking tea, and nearly every member of the main cast [[DefeatMeansFriendship joined after Reimu defeated them]].
** She isn't shunned by all humans, though. She and fellow outcast Marisa are HeterosexualLifePartners at the very least, a bond so strong it was one of the few things to survive the shift from PC-98 to Windows. In the manga especially, they're practically inseparable, eating together and shopping together and investigating together. Many chapters of ''[[Manga/TouhouSuzunaanForbiddenScrollery Forbidden Scrollery]]'' either start or end with them laughing and bonding over a meal that, to all appearances, makes them look like a married couple.
** Mima was pretty much obsessed with Reimu; her first major action was to wreck the Hakurei shrine so Reimu would fight her, and she later declared herself the god of the shrine seemingly just to keep hanging around her.
** In ''Story of Eastern Wonderland'', Reimu mistakes Meira's challenge for a marriage proposal and ''accepts on the spot''. She gets annoyed when Meira tries to clarify things.
-->'''Meira:''' I am Meira. I have come to take the Hakurei [powers].\\
'''Reimu:''' [[EngagingConversation Boy, that was quick...]]but okay!
** In Marisa's route against Flandre in the ''[=EoSD=]'' Extra Stage, she makes a comment about hooking up Flandre with Reimu.
** Yukari teases Reimu relentlessly and is frequently obstinate and unhelpful, but also gives Reimu important guidance, like clues to who the current incident culprit is. She trains Reimu to use her powers more effectively, alternating between TricksterMentor and outright flirting.
** Reimu has a weird trend of youkai basically barging into the shrine and becoming her roommates. Suika lived with her for a while until she moved to Bhava-agra, Orin wanted to be her pet, and though Shinmyoumaru's stay at the shrine was largely a prison sentence, they still bonded quickly, like Shin making a kimono for Reimu (which was way too small, [[CrowningMomentOfHeartwarming so Reimu wore it as a headdress]]).
** Reimu is known for being equally irreverent and brutally frank with everyone she knows—human, youkai, or goddess. The only exception to this rule is the little bookworm Kosuzu, for whom she even has a pet name!
* The [[ShrugOfGod always unclear]] and [[EpilepticTrees widely speculated]] relationship between Marisa and Mima tends to vary from master and servant, to mother and daughter, to even something romantic. Marisa's profile in ''Phantasmagoria of Dim. Dream'' states that she longs for Mima and refers to her with the extremely respectful honorific ''-sama'' (making Mima the only person in the entire ''series'' toward whom Marisa is ever polite and respectful).
* Some of the pre-battle dialogue with bosses can sound pretty flirty, such as this from ''The Embodiment of Scarlet Devil'' (Patchouli's presumably talking about ''literally'' eating Marisa—Patchy ''is'' a youkai—but it can certainly be taken the other way):
-->'''Marisa:''' I have enough. Of plenty of things.\\
'''Patchouli:''' Then I'll dig in.\\
'''Marisa:''' I'm really delicious.
* Patchouli has been living in Remilia's mansion for at least 100 years, serving no particular purpose other than being Remilia's closest friend. They are the only two characters in the series to call each other by nicknames—Remilia calls Patchouli "Pache" (sometimes romanized as "Patchy"), and Patchouli calls Remilia "Remi". Also, in a ''Forbidden Scrollery'' 4koma, Remilia calls for her chupacabra (which she is calling "chupa" at the time), and Patchouli comes and holds her hand instead.
* Sakuya is unwaveringly, inexplicably subservient to Remilia, to the extent that "Sakuya" is not even her original name; it was given to her by Remilia. There is absolutely no explanation for why a [[HypercompetentSidekick powerful, capable human]] has devoted herself entirely to a [[ImmortalImmaturity petulant, selfish brat of a vampire]], with several characters wondering how either of them can trust each other. Remilia implies and Akyuu speculates that Sakuya's been the Scarlet Mansion's head maid for a ''long'' time.
* Sakuya is quite friendly with Marisa despite the latter's tendency to break into the Scarlet Devil Mansion. The normally dutiful maid does a good job of stopping other intruders, but she's surprisingly lax when it comes to Marisa, especially considering that Remilia, Patchouli and Meiling would much rather keep the witch out. In Marisa's endings to ''Embodiment of Scarlet Devil'' and ''Phantasmagoria of Flower View'', Sakuya goes so far as to help her sneak in and serve meals to her.
* Youmu exhibits a devotion to Yuyuko similar to what Sakuya exhibits toward Remilia, constantly acquiescing to the whims of a [[ImmortalImmaturity millennium-old child]] but never shirking her duty. She was even willing to steal the essence of spring from Gensokyo and plunge it into eternal winter simply because Yuyuko told her to.
* Yuyuko and Yukari have been [[IntergenerationalFriendship close friends for more than a millennium]], even before Yuyuko died. In the present, they understand each other better than anyone else, the only ones who don't balk at each other's weirdness. Yuyuko's ''Perfect Cherry Blossom'' profile heavily hints it was Yukari who ensured that she would continue existing as a CuteGhostGirl, never resurrecting or crossing into an afterlife.
-->"My wish...is that she will never again reincarnate, and never again suffer pain..."
* Ever since Marisa and Alice met ([[ContinuityReboot again?]]) in ''Perfect Cherry Blossom'', they have formed a bizarre partnership unique in Gensokyo, based not on greater power or authority but [[BelligerentSexualTension lots and lots of snark]]. They almost the entirety of both ''Imperishable Night'' and ''Subterranean Animism'' arguing LikeAnOldMarriedCouple, often ''ignoring the boss'' just to trade snipes. And yet, they still hold a large amount of affection for each other; Alice is abrasive and rude toward everyone, but displays [[{{Kuudere}} a rare sentimental side]] with Marisa, while Marisa herself, though very much a JerkWithAHeartOfJerk, is far more respectful toward Alice than she is to anyone since Mima. They even share a bed in one of ''IN'''s Bad Ends.
* Eirin made an immortality potion—forbidden by law and punishable by exile—just because Kaguya asked her to. When sent to retrieve Kaguya from Earth once the latter's exile was deemed over, Eirin instead betrayed and ''killed'' her entourage, exiling herself from her home and her position as "Brain of the Moon" [[SubordinateExcuse so she could be with Kaguya]]. She even [[WillfullyWeak hides most of her power]] so that Kaguya isn't offended by a subordinate with more power than her, something completely unprecedented in ''Touhou''. This is even more significant since ZUN stated in ''Symposium of Post-Mysticism'' that Eirin is one of the ultra-powerful gods of the Moon.
* Mokou harbors a [[{{Immortality}} literally eternal]] hatred towards Kaguya for an "offense" made against her father centuries ago. Combined with Kaguya viewing their "rivalry" with amusement more than anything else, this makes Mokou seem more like a gigantic {{Tsundere}}. The semi-canonical ''Inaba of the Moon and Earth'' only seems to confirm what a {{Tsundere}} Mokou is, though as a GagSeries, it naturally plays fast and loose with characterisation to begin with.
* Mokou has been living as a hermit and vagrant for centuries, isolating herself from others because she [[WhoWantsToLiveForever can't bear to see them die while she never changes]]...except for Keine, who is literally Mokou's only friend and even tries to protect her. Mokou knows what will happen, but can't quite bring herself to avoid Keine as she does with everyone else.
* [[PhysicalGod Kanako and Suwako]] first met when Kanako declared war on Suwako's followers and won. Since then, they've been living together for about half a millennium, and they [[HasTwoMommies raised Sanae together]]. Not bad for two people who started as enemies. In addition, for worthwhile context, Kanako's character is apparently based off the actual Shinto goddess Princess Yasakatome, who lives in the Suwa Taisha shrine with another deity: her husband.
* Byakuren and almost the ''entire cast'' of ''Undefined Fantastic Object'', all literally worshipful of and intensely loyal towards [[FanNickname Youkai Jesus]]. Murasa, Shou, and Ichirin all had their lives transformed by Byakuren in the past, and in gratitude worked together to unseal her. This trait is carried on into later games; Byakuren's sheer {{magneti|cHero}}ism has caused her to accumulate by far the largest CastHerd in the entire series [[note]]Shou, Nazrin, Murasa, Ichirin, Unzan, Nue, Kyouko, and to an extent, Koishi.[[/note]], all devoted to her.
* Sanae B's Extra Stage in ''UFO'': Sanae actively refuses to believe that Nue could be a youkai and [[ImTakingHerHomeWithMe drags her off]] to [[NotADate get photos taken together]]. That's bad enough, but Sanae B is [[FantasticRacism not fond of youkai]]...
* Soga no Tojiko is based off of Tojiko no Iratsume. Toyosatomimi no Miko is a genderbent Prince Shoutoku. Historically, Tojiko no Iratsume and Prince Shoutoku were ''married''.
* ''Forbidden Scrollery'' has Kosuzu being rather...taken...by Mamizou's human guise, practically crushing hard over the tanuki-pretending-to-be-human and squeeing over the interesting books and recommendations she gets.
** Kosuzu is very close to Akyuu, enough for Akyuu to show her hidden cynical side and engage in banter even Reimu never gets to partake in.