- One episode of Ah! My Goddess: Flights of Fancy had Belldandy pitted against Sayoko in a drinking contest. At one point, Bell is still standing strong while Sayoko is having trouble speaking coherently... so she decides to bring a bottle of her most potent stuff — and collapses upon opening it and smelling its contents. Sayoko had to be taken away by paramedics, while Belldandy did eventually get drunk... on cola.
- The Ai Yori Aoshi anime has a bottle of liquor that Tina brought from America. It glowed in the dark. Taeko, the resident Meganekko/Cute Clumsy Girl drank a cup straight, and everyone thought it was fine. As it turned out, Taeko is just really good at holding her liquor, and naturally, Hilarity Ensued.
- The Prince of Tennis: Inui's juices are not alcoholic, but pretty much everyone on the team breaks out in a cold sweat at the thought of them, and even Fuji, who otherwise happily drinks anything Inui makes, passed out upon imbibing the "Aozu".
Gargle Blaster / Anime and Manga
Examples of Gargle Blasters in Anime and Manga.