- In Issue #1, The Doctor and his friends are riding around in a chariot in ancient Egypt. The Doctor even wears a royal crown for most of the ride, for some unexplained reason.
- Issue #2: Riker, Doctor Crusher, and Data hear the TARDIS materializing in the Holodeck, but mistake it for an error with the holographic simulation.
- The Doctor meets Lt. Cmdr. Data. Hilarity Ensues.
Doctor: An android! A positively splendid android! What do you have in here, a positronic brain? Those can be tricky to untangle, need lots of artificial synapse jumping. Looks like you've got it running very smoothly.
Data: Curious...
Riker: Um...
Amy: Doctor, you're being rude!
Doctor: Top-notch workmanship, I have to say. Did you build him yourself?
Data: Please let go of my head.- Worf tires of the Doctor's nonstop Gibbering Genius tendencies:
The Doctor: Very nice, very impressive. Roomy. I like roomy. I like the lines. Very nice use of space.Worf: Will you PLEASE stop talking! - Issue #3 has Spock giving a detailed analysis of the jelly baby that the 4th Doctor gives him.Spock: Fascinating. Gelatin confectionary, dusted with starch, and molded into the shape of small child.
- Upon first meeting him, Kirk and crew assume the 4th Doctor is another member of the Federation research team. An assumption The Doctor never bothers to correct.
- When fighting the Cybermen, the Doctor asks Kirk to distract them.
Kirk: Distract him. Sure.- Scotty referring to the Cybermen as "Mechanical Clankers".
- Issue #4, the Doctor, Amy and Rory experiencing the effects of the transporter for the first time.
- Riker's unease with the Doctor taking a sample of dangerous alien technology back to the Enterprise.
Doctor: Trust me, Commander! If there's one thing, I'm good at, it's gumming up the works!Riker: I'm getting a sense of that. - Issue #7, Worf rescues Rory from a squad of Cybermen, and then, holding him aloft by his collar, hands him to Amy.Worf: Watch him.
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