* In the episode "A Star Is Lost," after Gadget telling her about his new assignment to protect rock star [[StevenUlyssesPerhero Rick Rocker]] from MAD, [[NotSoAboveItAll the usually calm and level-headed]] Penny [[http://www.youtube.com/watch?v=ERUMWiGrmQQ briefly turns into a squeeing fangirl]], shaking Gadget by his collar to get him to take her with him.
** Mad Cat's reaction to the brainwashing record is also funny.
* Gadget acting drunk after someone drugs his drink in "A Race To The Finish," to the point where he starts doing donuts on the racetrack.
--> '''Gadget:''' Yoo-hoo! Look at me! I can do a donut!
* Gadget's horrifically bad attempt at flying a rickety airplane in "Photo Safari," starting with this exchange:
--> '''Penny:''' Are you sure about this Uncle Gadget?
--> '''Gadget:''' No problem, Penny! The nice mechanic said any fool could fly this plane!
** And fly it he does. Upside down, sideways, through buildings and nearly into the ground, all before leaving the runway area. What really makes it hilarious it is Penny and Brain's shell shocked reactions, though - while Gadget's whistling and singing, completely oblivious to the danger they were just in as usual, Brain's freaking out and Penny frozen to her seat looking like she's having trouble not joining him.
*** Though the fact that he's able to fly a plane that's falling apart ALL THE WAY ACROSS THE ATLANTIC OCEAN (they live in the U.S., they're going to Africa) [[HiddenDepths says something about his piloting skills.]]
* Don't forget [[http://www.youtube.com/watch?v=4gckb8VIDzg this scene]] from "All That Glitters"
--> '''Dr. Claw:''' You're supposed to be disposing of Gadget.
--> '''Mook:''' I've only got two hands.
--> '''Dr. Claw:''' What!? HOW DARE YOU!
* Most of Claw dealing with his idiot henchmen, but especially this from "Haunted Castle," after a backfiring trap sends a minion into the drip.
--> '''Dr. Claw:''' ''What were you doing in the moat?''
--> '''Henchman:''' "Well... uh... Well, I... uh...
--> '''Dr. Claw:''' '''What happened to Gadget?'''
--> '''Henchman:''' Well, uh... I don't know, sir...
--> '''Dr. Claw:''' '''YOU DON'T KNOW? WHERE IS HE NOW?'''
--> '''Henchman:''' Well, I'm not sure...
--> '''Dr. Claw:''' '''''NEVER MIIIIIIIND!!!'''''
* Gadget getting offended at the beginning of "Busy Signal" when Penny tells him his gadgets have been surpassed.
-->'''Gadget''': What's that you're reading, Penny?
-->'''Penny''': I'm doing the research for my report on the history of computers. It says here that most of the gadgets the doctor put in your body have now been surpassed.
-->'''Gadget''': '''Hmph.''' [[GoToYourRoom It's time for your bath, Penny]].
* Anytime Gadget tries to teach Penny something but ends up messing it up and embarrassing himself instead.
* [[https://www.youtube.com/watch?v=zUgzigD_cgg This scene]] speaks for itself.
* The episode "Quiz Master" has a funny bit where a M.A.D. agent disguised as a bearded caveman in a stovepipe hat tries to waste Gadget, only for the bumbling detective to avoid the attack and say "Sorry, Mr. President".
* This exchange from "Gadget's Clean Sweep".
-->'''Dr. Claw''': You must get the Crown Jewels. I wanted them since I was a child.
-->'''Thelma Botkin''': You were a child?
* In the "Volcano" episode, Gadget's following Brain, who is disguised as a hula girl and gradually shedding the disguise. By the time Gadget finds the ''skirt'', the look on his face is absolutely priceless.
* The M.A.D. Agents mistaking the real Gadget for his robot duplicate in "Doubled Agent", especially when HilarityEnsues once the real Gadget asks the agents if they can stop for ice cream.
* The second episode featuring the Great Wambini and the Lesser Wambini has the Lesser Wambini attempt to stall the rich pet owners at the phony seance by doing shadow puppets. When the Great Wambini hears the cops coming and drags his assistant with him to their escape, the Lesser Wambini is ''still'' doing shadow puppets and is apparently oblivious of what is happening around him.
* "The Infiltration" has Gadget confronting Presto Changeo, each insisting that he's the real Gadget. The real Gadget stands near Chief Quimby, and then Gadget's mallet activates by itself and bonks Quimby on the head. Needless to say, this helps Quimby SpotTheImpostor:
-->'''Quimby''': ''(Pointing at Presto Changeo)'' Arrest that man! ''(Points at Gadget)'' This has '''got''' to be the real Gadget.
** Gadget's {{Leitmotif}} playing as Quimby says this makes it all the funnier.
* Dr. Claw's reaction as Gadget is about to flood MAD's underwater base is a combination of OhCrap and FreakOut, verging on VillainousBreakdown as he realizes that the base is ''doomed''.
* By far the most hilarious of Dr. Claw's minions, however, has to be Macho Miguel from "The Emerald Duck". The guy is CMOF personified; he's [[LargeHam so flamboyant and over-the-top he's laugh-out-loud hilarious every time he's in a scene]]. Some notable entries:
** [[https://youtu.be/5CGkN79-6sg?t=1m35s First scene.]]
--->'''Museum Receptionist''': It was first discovered in...
--->'''Macho Miguel''': Areba! (''Mariachi band plays MM's theme.'') It is I, Macho Miguel!
** [[https://youtu.be/5CGkN79-6sg?t=2m28s Making his escape with the Emerald Duck.]]
--->'''Macho Miguel''': Viva MAD! Viva Dr. Claw! Areba! (''sprints out of scene, then comes back because the mariachi band isn't playing'') Maybe you didn't '''hear''' me. I said, AREBA! (''band plays'') That's more like it!
** [[https://youtu.be/5CGkN79-6sg?t=4m15s Dr. Claw contacting Macho Miguel.]]
--->'''Dr. Claw''': Dr. Claw calling Macho Miguel. Come in, Agent Miguel! Where is that idiot?
--->'''Macho Miguel''': Areba! (''jumps into the scene on Claw's computer, along with his mariachi band.'') Macho Miguel is here!
--->'''Dr. Claw''': '''Enough, you fool!'''
** [[https://youtu.be/5CGkN79-6sg?t=7m7s After Dr. Claw orders him to get rid of Inspector Gadget.]]
--->'''Macho Miguel''': And now, I make my Macho exit! Areba! (''runs into wall'') Eh-yow!
--->'''Dr. Claw''': Forget the theatrics, you fool! '''Just get Gadget!'''
** [[https://youtu.be/5CGkN79-6sg?t=9m56s Random attempt to kill Gadget, who thinks MM is helping him, as usual.]]
--->'''Inspector Gadget''': It certainly is a long way down...
--->'''Macho Miguel''': Yes, '''isn't it'''! (''pulls a lever releasing the ledge under Gadget, laughing'') Adios, Inspector!
--->'''Inspector Gadget''': Wowzers! Go-go-Gadget-copter!
--->(''Gadget uses his helicopter to avoid falling, and Brain in disguise winds up falling with the ledge instead'')
--->'''Inspector Gadget''': I guess they don't make mountain ledges like they used to!
--->'''Macho Miguel''': Santa maria!
** [[https://youtu.be/5CGkN79-6sg?t=18m25s By far the funniest, Macho Miguel making his way to the pedestal that he can use the Emerald Duck on to activate the weapon Dr. Claw wants.]]
--->(''Macho Miguel finishes climbing the cliff side, and stops to catch his breath.'')
--->'''Macho Miguel''': Huh?
--->(''Mariachi band, standing on the cliff, starts playing MM's theme again.'')
--->'''Macho Miguel''': '''How did you get-'''
* "The Japanese Connection" had some pretty funny bits:
-->'''M.A.D. Ninjas''': Konichiwa, Gadget-san. We are about to do away with you!
-->'''Gadget''': Ah so!
** Later on in the episode:
-->'''Sumo Wrestler''': Ohio!
-->'''Gadget''': Oklahoma!

[[AC: 1999 Film]]

* In a movie filled with groaners, when Gadget is battling the evil Robo-Gadget, he's hanging over the edge, holding on by his tie:
-->'''Robo-Gadget:''' Hey Gadget - it's a clip-on!
* "''[[AsideGlance Somebody's]]'' been watching too many Saturday morning cartoons!"
* During Robo-Gadget's rampage across the city:
-->'''Japanese Man''': [[Franchise/{{Godzilla}} THIS IS WHY I LEFT TOKYO!]]
* And how can we possibly forget the part of Inspector Gadget's training session where his guru tells him to focus completely upon "obtaining the balls." More specifically, a pair of balls on the floor in front of him. Gadget's cybernetic hand extends as desired...and then it ''keeps going,'' rocketing [[GroinAttack straight at another pair of balls...]]
-->''[The Guru screams like a little girl; cut to the observation room, where the onlookers wince in sympathy]''\\
'''Guru''': (In the highest-pitched voice imaginable) Ungrip! ''Ungrip!'' Turn it off! TURN IT ''OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOFFFFFFFFF!!!!!!!''\\
'''Chief Quimby''': Well, I guess [[Series/TheSixMillionDollarMan six million dollars]] doesn't buy what it used to.\\
'''Brenda''': Excuse me.\\
''[As hospital workers put the guru in an ambulance, with an ice pack on his crotch]''\\
'''Guru''': (''Still'' in the highest-pitched voice imaginable) He is not a man, you know. Oh! He is a monster! (Sobs in pain)
* When Brown wakes up after the operation and sees all sorts of stuff (pencil, bubble wand, lighter, etc.) coming out of his hand, his response is "What have they got me on?"

[[AC: 2003 Sequel]]

* The opening sequence where Gadget arrests an elderly woman for going ''0.3'' miles above the speed limit. Said old lady turns out to be ''Chief Quimby's mother!''
-->'''Chief Quimby''': Where is he?! '''[[SayMyName GADGET!!!]]''' You put my mother in jail for drag-racing?!\\
'''Inspector Gadget''': And driving without a license. You always said, Chief, "No one is above the law."\\
'''Chief Quimby''': That's what you said last week when you arrested that group of girl rangers for ''selling cookies!''\\
''([[FlashbackCut flashback shows said girl scouts posing for mugshots]])'' \\
'''Inspector Gadget''': Those "cookies" were three days past expiration date!\\
(''Quimby gets his hand in bubble gum!'')\\
'''Chief Quimby''': You are ''this'' close to being put on probation, Gadget! Now, let's get my mother out! Heaven knows what's happening to her down there with all those lowlifes!\\
(''[[DescriptionCut cut to Mama Quimby in the prison cell beating the crap out of the prisioners]]'')\\
'''Mama Quimby''': Who's your granny now?! HUH?!\\
'''Inspector Gadget''': Wowzers! That's gotta hurt!\\
'''Chief Quimby''': Mom's tough love. This your last warning, Gadget: Stick to solving ''real'' crimes!!\\
'''Inspector Gadget''': But, Chief, there are no criminals left! They're all in Riverton prison!\\
(''Cut to a stormy night at Riverton Prison as a claw bursts out from under the earth!'')