In the good timeline, which according to Word of God is canon, Cole and all other conduits are killed. At the end, however, the lightning forms a question mark, implying he may still be alive. What's to stop other, less heroic conduits like Sasha, with no confirmed death, to survive the blast? Better yet, what's to stop the conduit gene to merely reemerge, just starting the cycle back over again?
Bouncing off that and the horror down below, It's entirely possible Sasha could exist in any of the three timelines, escaping capture by Moya with no confirmed death. The destruction of Empire City was probably caused by him creating new conduits, being a living ray sphere, and she could have lived beneath the sewers as she always did, unaffected by the blast or destruction of the city, or the plague due to being a conduit. Thus, she can exist in any timeline, having likely lived into the events of inFAMOUS 2. In the good, explained above. In the evil, all conduits live while humanity dwindles to extinction due to the plague. She lives unless some other conduit kills her, unlikely, and would probably not be stopped by beast!cole due to him being evil and in New Marais, or other southern cities. In Kessler's timeline, if he didn't create the ray sphere yet, then you can get powers naturally, once again by the beast. She would be weaker, but still possessing the conduit gene, she might get caught in the blast and still gain powers. You are never safe from Sasha, and neither is the world, even with time travel.
John/The Beast has to suck energy out of a few dozen people to awaken a Conduit. So... were the Conduits, besides the main four, in the first game created the same way, somehow?
In a way, yes. Those conduits were affected by the Ray Sphere energy, but weren't in the center like Cole or Bertrand. Like Nix, they were in the proximities, and probably absorbed the energy that people around emitted.
It's specified in the dead drops that blast cores are used ray sphere cores. When I got this dead drop on my second playthrough, it hit me: Cole absorbs seven blast cores over the course of the game. Oh, shit...
Worse yet, Wolfe's dead drops account for two more. He discovered the blast core's potential after a lab animal accidentally absorbed one, and it's implied that another gave Bertrand powers beyond his "maggot" transformation, presumably the Corrupted-making powers.
This becomes even worse when you realise that there was no blast core from cole's ray shpere as cole destroys it (accidentaly when reactivating the ray sphere or on purpose when destroying the ray shpere) at the end of the first game. That means aside from Cole's there were 9 other ray sphere's that Wolfe tested the detonated cores on.
It's revealed that Joseph Bertrand is the one creating the swamp creatures, and they come in several varieties: human-sized, Ravager, Hive Lord, and such...but there's also a tiny version that can be taken out in one hit, doesn't do much damage, and is overall inferior to all the rest. So...where did that type come from? Simple. No one said that adults were the only ones Bertrand was transforming...
We know where they come from. We see the Hive Lords spawn them.
In a mid-game mission, Cole and Zeke are trying to get plague victims to a medical station to give them painkillers to ease the pain. When Zeke first tells Cole about the Dunbar beam, he mentions that while it doesn't have the explosive effect it does on swamp beasts, the super-focused UV will probably give them melanoma, but dismisses it since the plague is killing them anyway. Fast-forward to the good ending when the plague is gone, most of the people survived, but will now have to deal with an even more excrutiating ordeal as they either try to cure or succumb to skin cancer.
When you you're on the good ending you kill all people with the conduit gene, that means besides all the living people that die, the unborn children die as well.
Assuming only the father had the gene, yes. Now what if the mother has the gene, but the fetus doesn't? Unless they get them to the hospital for a C-section...
Kessler as a usable skin for Cole. Why would you ever want to make yourself look like the preceding game's villain... oh.
In the Good Ending he sacrifices himself and all conduits to destroy the beast. A few missions before hand he was able to absorb Lightning from the Storm that had moved into the city. In the very end of the game's good ending There is a lighting storm there.
The reason for the final fight against The Beast being the most ridiculous Curb-Stomp Battle of the century is actually justified by more than just that. We see in the evil ending what happens when Nix uses the RFI against The Beast; it weakens him. The RFI isn't fully charged, and Nix is a weaker Conduit than Cole. In the good ending, the RFI is fully charged and being used by a stronger Conduit, so instead of just weakening The Beast, it straight up incapacitates him.
The RFI is the thing that ultimately defeats the Beast. It was made by someone other that Kessler, to clean up the plague created by Kessler. The Beast was also created by Kessler. The lesson? Kessler creates problems, not solutions.
While Cole's relationship with Kuo is purely professional, if the player chooses to be evil, his tone and behaviour with Nyx is flirtatious and innuendo laden. So soon after Trish dies? But then, while a good man would keep her memory with him always, if a person is following Nyx's questlines, they're not a good man, and are less likely to stay faithful.
In New Marais, sometimes you'll get XP credit for takedowns accomplished by civilians throwing stones at enemies, if you have good Karma. A little thought reveals the logic: the civilians standing up against the Militia and other enemies is a direct result of Cole gaining their trust and inspiring them, so their small victories over the villains are, in a sense, Cole's victories as well. One more subtle way in which Evil pays off quick, but Good pays off big.
A prime example of this: i once saw a civilian single-handedly punch an ice soldier to death.
A lot of fans were angry with Cole's new clothing in inFamous 2. He's headed south from the New York parallel to the warmer New Orleans parallel, it makes sense that he would shed a jacket.
The plot of inFamous was all Kessler's plan to make Cole stronger so he can defeat the beast. At the beginning on inFamous 2, Cole defeats the beast losing all his powers and almost dying in the process. Kessler's training worked after all, the only problem is Kessler didn't account for the fact that the beast can put itself back together