Mongrol and Mek-Quake from the ABC Warriors; Mongrol is a battered, punch drunk colossus whose mind was scarred by war and torture until he considered his brain to be a second party that he must occasionally parlay with, while Mek-Quake is a one-mek wrecking crew whose only aptitude and only joy is in violent acts, known to him as "big jobs".
She meets her match in the first issue of their own series: Mr. Mental is an extremely powerful telepath who is really really really stupid. "Try your helmet! Hit 'em with a blast of telekinetic power!" "Oh, is that what this is for? I thought we'd been playing soldier!"
Two deputy Plexus Rangers in American Flagg!: the robotic Luther Ironheart and the Husky Russkie Yuri Kholyakov.
Obelix from Asterix is the strongest warrior in the series and has permanent superhuman strength. But as an effect of this, he is slow-witted and easily confused.
Jitterjack from Astro City can literally tear a person apart with his bare hands, but his Hulk Speak and other mannerisms indicate serious mental difficulties.
Most incarnations of Killer Croc, particularly in Batman: The Animated Series and current comics. The exception here is The Batman, which, in addition to a Race Lift making him Cajun, made him a bona fide criminal mastermind of his own. This was actually truer to the original version of Croc introduced in the comics of the early '80s, before Flanderization set in and writers portrayed him as nothing but a savage brute. Though, on the other hand, Killer Croc in Batman: The Animated Series did pull off a very intelligent frame job against Harvey Bullock in his first appearance. Then he basically just became comic relief Dumb Muscle.
Other villains in the DC Animated Universe, like Rampage, Solomon Grundy, and (the first) Blockbuster, also count, as do their comics counterparts.
And their fellow Blackgate inmate Titus Czonka, the Baffler. Very stupid but phenomenally powerful, he made the mistake of trying to be a more traditional Batman villain as The Baffler, a second-rate ripoff of his cohort the Cluemaster who was himself a second-rate ripoff of the Riddler. So the stupid guy starts leaving ridiculously simple clues for the authorities to catch him with. The only time he almost succeeded with a plan it was because Robin and Spoiler didn't take him seriously and he nearly got himself killed as well.
Cable & Deadpool: Prester John, a gigantically muscled man who dwarfs even Cable in size. Among other things, he is utterly perplexed at the motive behind the murder of the Marvel Comics equivalent of Osama bin Laden. As it was explained to him, "He wanted him to stop being the world's most wanted terrorist." His reply? "Well, it worked."
DCU villain General Wade Eiling was originally a very clever villain but was reduced to this when he transferred his brain patterns to a Shaggy Man body to avoid dying of cancer. The Shaggy Man's brain was incompatible with Eiling's mind and he became a dumb brute as a result.
Gorgilla and Elektro of the Fin Fang Four; Elektro is a robot with a 32k processor (later upgraded to 64k; as Elsa Bloodstone puts it, "I've got JPEGs smarter than him."), while Gorgilla has grade-A Hulk Speak and intelligence. Both are also incredibly powerful and destructive given the proper motivation.
The Flash villain Big Sir, who was born with severe mental deficiencies and a glandular problem that caused him to grow into an extremely large man of over eight feet. The Monitor gave him equipment to become a supervillain, taking care to include a headset that periodically emits a beeping noise so he'll remember to stay on task.
Block in Hero Camp, who is almost completely illiterate; When we're shown a book from his perspective, it's almost entirely gibberish and he can only understand a single sentence on the page. He's also so slow that he thinks his incredible weight is due to obesity, when he's actually made of solid rock without an ounce of fat on him.
His original characterization, circa joining The Avengers, had him as more of a temperamental, rebellious teenager. Though note there is a difference between childlike and stupid, and the Savage Hulk can be remarkably cunning and shrewd when the situation calls for it.
Although, really, most Hulk villains besides the Leader and MODOK are brawny, brainless monstrosities.
This side of him is played up considerably in Twisted Toyfare Theater, which also features Bizarrobama, the Prime Minister of Canada and an imperfect clone of Barack Obama.
Roxy from Jem and the Holograms (IDW) is The Ditz of her band, is the most muscular main character, and likes boxing (like her bandmate Jetta). The fact she Never Learned to Read is unrelated to her ditziness and never gets poked fun at.
Several Marvel Comics villains like the Rhino, the Sandman, the Blob, and the Ox.
The Ox can trounce She-Hulk with minimal effort and punch colossal holes in brick walls but doesn't grasp the concept of figurative language; when his and Boomerang's lawsuit against the Vision is settled "for an arm and a leg", he violently insists he wants cash and couldn't care less about having a robot's limbs. This is the result of heavy Flanderization: while Ox was always the strongest of the Enforcers, he originally was just somewhat stronger than Spider-Man and somewhat less clever than Montana or Fancy Dan.
Lead of DC's Metal Men is a very strong example, being incapable of completing a thought without stumbling through it with several "Uhmm"s as well as being the toughest of the group (though Iron is slightly more powerful).
The mysterious Zombie, alias John Doe, from Nick Furys Howling Commandos. Big, strong, and with extremely stunted intelligence. This might actually be a Stealth Pun: Zombie could use some brains.
Yeagar from Nodwick is the party fighter and has sub-par intelligence and wisdom scores. In-story he tends to get confused by big words, metaphysical concepts, or most things that cannot be treated by stabbing, imbibing, romancing or looting it.
Captain Everything in normalman. Cap is, well, a moron who has been known to forget how to fly in midflight, but he's so childlike it's hard not to like him anyway. So, while he causes needless destruction and fights his own friends just because he thinks the scene needs action, he's still completely guileless and doesn't have a mean bone in his body.
Captain Marvel's naïveté tends to come across this way, but since he's a kid in an adult's body, it's excusable. He also has the Wisdom of Solomon, so he's extremely insightful when he remembers to be.
Played with in Sin City. Marv is not educated and considers himself stupid but he displays a knack for solving mysteries and figuring out a way to defeat a skilled opponent.
Spider-Man has several villains who aren't all-hands-on-deck Avengers-level threats because they just don't have the brains to use their powers to their fullest extent.
Electro can control electricity, which should put him around Magneto's level, but the guy has no ability to plan ahead beyond his latest dumb grudge, and never bothers to master his powers. He can't even use his powers to go legit because he's too much of a petty jerk to keep any job longer than a few days.
Rhino was chosen to get his armor suit because his bosses in organized crime thought he was dumb enough to be easily controlled. For the record, they were right.
Sandman downplays this depending on whether he's a heel or a face this week, but he's always incredibly tough (he can be as solid as granite, or flow around blows like sand), but often terribly uncreative.
Hydro-Man has Sandman's problems taken up a notch; his water control could make him a global threat or filthy rich, but Hydro can't think of anything better to do with it than clobber Spider-Man... and he's so careless that he keeps defeating himself while he's at it.
Dengar. A big, beefy lunkhead, he at least has the excuse of having suffered brain damage in a swoop bike race with Han Solo. Combine that with the loss of sanity from the experiments the Empire did on him afterward to program him as an assassin, it's actually a wonder that Dengar functions as well as he does.
Gamoreans are a species whose entire Hat is being Dumb Muscle.
Doomsday barely has any mind to speak of at all. Due to the multiple deaths he suffered during the experiments that created him, Doomsday is little more than a frightened and enraged baby. Imagine an infant trying to swat away something scary with his little baby fist. Now imagine that said baby could topple a mountain with that swat and you've got Doomsday. The one time he was given intelligence it rendered him weaker because it exposed his true nature as an infantile coward terrified of death.
Bizarro and Bizarrogirl, though not to the same degree as the usual Bizarros. Bizarrogirl is capable of learning from her mistakes -even though she needs a bit of help of Supergirl- and doesn't get everything backwards.
Kaliber from Superboy and the Ravers is a super-strong Qwardian with a very simple worldview who luckily idolizes heroes and is therefore generally on the same side Superboy, although he's easily duped.
Tiger Division from Marvel Comics has its founder and field leader, Taegugki who's also South Korea's greatest hero due to his godlike power levels. Unfortunately he's headstrong, rather awkward and really dumb especially for a guy who's well into his seventies. In one instance, while fighting a bunch of robot mooks, instead of using his Eye Beams or at least using his Super-Strength more wisely, he grabs the robot and flies it into the main support pillar of the building Tiger Division was investigating which collapses the building. There's a good reason despite being much younger, Ami Han the White Fox leads the team officially while the sorceress Bright Lady helps him do the thinking on-site.
Thor is a subversion. His plan A is always "Hit it with Mjolnir until it stops resisting." and given his strength and weapons, there is rarely a need for plan B. However, Thor is more thoughtless and impulsive than stupid, and displays a lot of cunning when circumstances force him out of his comfort zone.
Played straight with the Jotuns Hymir and Hrugnir, however, both of whom are physically powerful (Hymir more in that he's built for manual labour than an outright fighter; he is able to pull whales out of the ocean when fishing) but also dumb as a post. Hrugnir is also extremely crude and short-sighted; Tjalfe is able to trick him into letting his guard down by convincing him that Thor can throw Mjollnir through the Earth and attack people from below.
Wild C.A.T.s (WildStorm): Maul actually gets dumber as he gets bigger. He once got so big he forgot how to return to normal size. He is a bizarre case: while his power is that he can swap brains for brawn, in his "normal" form he's a Nobel laureate: so, when he doesn't grow too much, he retains enough smarts to be more like a Genius Bruiser.
The Lifter (an airheaded superhuman weightlifter) and Mover (a Gentle Giant who lets his girlfriend Shaker do that thinking).
American Icon and the Romancer are arguable examples as well, while the Human Shield is a giant beast who only recently overcame his lifelong struggle with illiteracy.
Wonder WomanVol 1: Giganta starts out as a Killer Gorilla, and after her transformation into a large Super Strong woman her mental capacity is unchanged. The fact that the heroes know this becomes an issue after Dr. "fixes" this mistake since they're still expecting her not to do much thinking and she's become quite clever and calculating, and no less pissed off at the world at large making her far more dangerous.
Though you wouldn't know it most of the time, this role is often filled by Wolverine of all people in the X-Men. Yes, the expert survivalist who speaks 17 languages. Of course, Wolverine's a moron in a more social sense, and while he is very knowledgeable in areas concerning, to be frank, killing guys, he can have trouble with almost anything else.
And several other X-Men, as well. Sunder of the Morlocks (virtually retarded, mountainous size and strength), Basilisk (in Xorn's "special" class, giant-sized, weight off the charts), Rockslide (a muted example; not the strongest X-Man around, but just a tad above "moronic" intelligence wise), and Onyxx (who seems to have stopped developing mentally around age 12).
