''Black Hole'' is a twelve-issue comic book limited series written and illustrated by Charles Burns and published jointly by Kitchen Sink Press and Fantagraphics. Published between 1995 and 2005, the first four issues were released by Kitchen Sink Press before they went out of business, Fantagraphics took over. A compiled hardcover volume was released by Pantheon Books in 2005. The entire story is collected, but supplemental material shown on the covers and endpages of the individual issues are omitted.

The plot of the comic series follows a number of Seattle teenagers who, over the summer, contract a mysterious sexually transmitted disease known as "the Bug" or "the teen plague," which causes them to develop bizarre unique physical mutations, turning them into social outcasts. In particular it follows four teenagers, Chris, Rob, Keith and Eliza, switching back and forth between their stories as they come in contact with and contract the disease.

The suggestion of a film has been up in the air for a while. In November 2005, the Comics Journal message boards reported that Black Hole would be adapted to film by the French director Alexandre Aja (Haute Tension). In March 2006, comics news site Newsarama reported that Creator/NeilGaiman and ''Film/PulpFiction'' co-writer Creator/RogerAvary would be adapting the screenplay, and in May 2006 Gaiman confirmed this in a Time magazine interview. Neil Gaiman and Roger Avary later left production with it moving to Paramount Pictures and the direction of Creator/DavidFincher. Fincher abandoned the project to focus on the American remake of ''Film/TheGirlWithTheDragonTattoo''.
!!Tropes associated with this work:

* BittersweetEnding: [[spoiler: Keith & Eliza leave Seattle to their own EarnYourHappyEnding, while Rob ends up murdered in the forest, leaving Chris alone and unsure about her future.]]
* BodyHorror: What The Bug does to all of its victims. Some can hide it, others can't.
%%* CantGetAwayWithNuthin
* ComingOfAgeStory: A weird example, certainly, but it's there.
* DeliberatelyMonochrome: A black and white comic.
* FanDisservice: The sex scenes are often times cancelled out by the mutations.
* FreakinessShame: Averted with Keith's positive reaction to Eliza's [[spoiler:tail.]]
* MagicalRealism: Sort of.
* ManicPixieDreamGirl: Eliza
%%* NestedMouths
%%* RuleOfSymbolism
* TheSeventies: When the comic takes place.
* SurrealHorror: While the overall plot makes sense, the imagery and dream sequences alone push it into this territory.
* TrademarkFavoriteFood: Eliza's "best sandwich in the world": bologna, lettuce, and Miracle Whip ("Never mayo") on white bread.
* TwoLinesNoWaiting. The comic jumps from plot thread to plot thread multiple times.
* WhamEpisode: Issue #8, "Lizard Queen," which ends with [[spoiler:Rob being murdered.]]
* WhatHappenedToTheMouse: Keith's mutation from the bug is unseen in later scenes in the comic, without any explanation given.
* WholePlotReference: Of the emergence of [=AIDS=] in suburban seventies America.