* While Mario and VideoGame/DonkeyKong have both ascended to stardom since their debut game, Pauline, the girl they fought each other for the first place faded into obscurity as Princess Peach took over her role as DistressedDamsel in the ''Franchise/SuperMarioBros'' games. She did reappear in ''VideoGame/DonkeyKong94'', only to disappear for another decade until ''Mario vs. Donkey Kong 2'', in which Pauline's relationship status to Mario was demoted from "girlfriend" to "friend". However, she does appear (instead of Peach) in the ''VideoGame/MarioVsDonkeyKong'' games ''March of The Minis'', ''Minis March Again'', and ''Mini-Land Mayhem''.
** Donkey Kong Junior hasn't appeared since ''Game & Watch Gallery Advance''.
*** Though, this depends on which continuity you subscribe to. According to Rare, the Donkey Kong seen from ''VideoGame/DonkeyKongCountry'' on forth ''is'' DK Jr., while SelfDemonstrating/CrankyKong is the previous DK. ''VideoGame/DonkeyKongCountryReturns'' retcons it, however, to current DK being Cranky's grandson, meaning that DK Jr. really has been MIA ever since.
** Stanley, from ''Donkey Kong 3'' also vanished from the series appearing only in some cameos like ''VideoGame/WarioWare'' or ''VideoGame/SuperSmashBros''. It's unclear, but it's said he's also the protagonist from the Game & Watch ''Greenhouse'' and it's also rumored that he is Mario's cousin.
** [[VideoGame/SuperMarioBros2 Wart]] similarly disappeared.
*** This one actually makes sense. Wart was nothing but Mario's dream... Except [[FridgeLogic so were several enemies]] who made appearances in later games.
**** This could, however, be explained as Mario dreaming about creatures that actually exist, but which players had simply not yet seen.
** ''VideoGame/SuperMarioLand'': Tatanga seems to have ceased to exist. He kidnapped Princess Daisy in ''Super Mario Land'', appeared as a boss in ''Super Mario Land 2'', and was never heard from again.
** Chronologically, [[VideoGame/YoshisIsland Shy Guys appeared as enemies for Yoshi]] before the events of ''VideoGame/SuperMarioBros2''.
** Poochy had an entire level designed around him in ''VideoGame/YoshisIsland'', but was absent from new titles after ''VideoGame/YoshisStory'' and before ''VideoGame/YoshisNewIsland''.
** Plum, Charlie, Sonny, Harry, and Maple, human characters who are playable in ''VideoGame/MarioGolf'' for the Nintendo 64. They have not made a single appearance in any game since, unless you count Plum's cameos in ''VideoGame/SuperSmashBros Melee'' and ''Brawl'' as a trophy and sticker respectively. Not to mention that that's ''five out of fourteen'' playable characters.
** Toadette also seems to be a short-lived character, first appearing in ''VideoGame/MarioKart: Double Dash!!'', then making periodic appearances in Mario games until ''Super Mario Sluggers'' nearly five years later, then never appearing again. After another five years, she reappears in ''Mario Kart 8''.
** Bowser's Koopalings have a long and convoluted history of being PutOnABus. They first appeared as recurring antagonists in ''Super Mario Bros. 3'', ''Super Mario World'', and ''Yoshi's Safari'', then vanished without mention for over a decade before reappearing in ''VideoGame/MarioAndLuigiSuperstarSaga'', then vanished again, then reappeared a second time in ''VideoGame/NewSuperMarioBrosWii'' (with their original relationship to Bowser having been {{retcon}}ned away) and have been making fairly regular appearances since.
** All the original characters from ''VideoGame/SuperMarioRPG'' like Geno or Mallow [[ExiledFromContinuity are property of Square-Enix, therefore they simply vanished]] from all the subsequent Mario games except from a brief cameo of Geno in ''[[VideoGame/MarioAndLuigiSuperstarSaga Superstar Saga]]''.
*** On a related note, Mario RPG characters in general rarely reappear in other Mario titles. Exceptions include Goomba King, Baby Peach, and the Star Spirits, although in Baby Peach's case her debut in ''VideoGame/MarioAndLuigiPartnersInTime'' was likely coincidental. ''VideoGame/PaperMarioStickerStar'' is notable for not returning any previous ''Paper Mario'' characters and only using characters from the main series, introducing only Kersti as a new character.
** Even Luigi went through a low hiatus for almost ten years. Eventually he came back though. Similarly, Mario rescued Daisy in an old Game Boy title and she didn't appear again for years. Now she's a standard of spin-off party games.
* Zhuzhen and Halley from the original ''VideoGame/ShadowHearts'' are unmentioned in the sequels. This may be somewhat justified, though, in that the former returned to China while the later left for America. The Valentine family gleefully subvert this.
* Dynamo in ''VideoGame/MegaManX5'' and ''[[VideoGame/MegaManX6 X6]]''. The only antagonist in the series to remain alive and intact (that is, not coming BackFromTheDead), he worked for Sigma in ''X5'', returned in an arbitrary cameo in ''X6'', and vanished off the face of the earth.
** Similarly, Douglas only appears in ''X5'' and ''X6'', then disappears after that. Lifesaver only appears in ''X5'' (granted, he wasn't very popular due to his NiceJobBreakingItHero action). Dr. Cain was last seen in ''[[VideoGame/MegaManX3 X3]]'', last mentioned in ''[[VideoGame/MegaManX4 X4]]'', and gone after that.
*** The UpdatedRerelease ''Maverick Hunter X'' has Dr. Cain dying in an attack on the Hunters' headquarters; whether this is a {{retcon}} or not remains unclear.
** In the ''VideoGame/MegaManStarForce'' series, Pat Sprigs is a major character in the first game, cameos in the second, and vanishes in the third. What's frustrating is that the game itself acknowledges that it still has plot points to wrap up regarding him. Pat also disappears from the anime as well, only to make a very minor cameo at the end of the final episode.
* In ''VideoGame/{{Xenogears}}'', Billy's dad Jessiah disappears (much like most of the game) when Disc 2 starts. At least, from the storyline, technically he is still around as he is is the gun/bullet in one of Billy's gear's special moves. Oh, and Kaiser Sigmund too - despite the fact that an early Disc 2 plot point would probably have him heavily involved. Disc 2 has a much tighter story focus than the first disc, playing more like an interactive novel than a standard RPG, and the planned storylines for both characters may have gotten lost in the same budgetary constraints that are rumored to have caused the gameplay shift.
** Yui, Citan's wife, also vanished from Disc 2 onwards, although it's implied that [[spoiler:[[FridgeHorror she may have become a Wels like most of the other ordinary people]].]]
* Parodied in ''[[VideoGame/BanjoKazooie Banjo-Tooie]]'', where the face of Tooty, DistressedDamsel of the first game and kid sister of Banjo, appears on [[FaceOnAMilkCarton a milk carton]] in CloudCuckooland, one of only two appearances of Tooty in the game (the picture of her in Banjo's house from the previous game is still there; in fact it's one of the few things in the house that is not significantly damaged or destroyed). Rare obviously never saw her as anything more than a [[FlatCharacter walking plot device]] for the first game, and thus hand-waved her absence circa ''Nuts and Bolts'', saying she was hauled off by the "Rubbish Video Game Characters Police".
** Brentilda completely vanished as well. Her only appearance is in a portrait in Pawno's Emporium in Jolly Roger's Lagoon.
* Every surviving character from ''VideoGame/MetalGear'' and ''VideoGame/MetalGear2'' that didn't make the transition into the ''VideoGame/MetalGearSolid'' series was forgotten by default: Ellen Madnar, Diane, Jennifer, Holly White, [[strike:Yozef Norden]] Johan Jacobsen, and George Kasler.
** Subverted with Meryl, who vanished without explanation, except for an implied reference an optional conversation in [=MGS2=] in which Snake says he's had enough of tomboys. Players were left to assume that the ending of [=MGS1=] in which she died was canon, until she showed up in [=MGS4=].
** Surprisingly enough, this is Averted with Dr. Pettrovich Madnar in [=MGS4=]. While he doesn't make an actual appearance, it's explained that he saved Raiden's life behind the scenes, even though he hadn't been mentioned at all in the last games, and him being the original creator of the first Metal Gear had long since been retconned.
* Many ''{{Franchise/Sonic|TheHedgehog}}'' characters like Ray the Flying Squirrel, Mighty the Armadillo, Bean the Dynamite, Bark the Polar Bear, Nack the Weasel (a.k.a. Fang the Sniper), Mecha Sonic, Tails Doll, Gemerl, and Metal Knuckles have been subject to this.
** Several of these characters got [[TheCameo cameos]] on "Wanted" and "Missing" posters in ''VideoGame/SonicGenerations''. Mighty and Ray are listed as [[LampshadeHanging "Missing since 1993"]] (even through Mighty was last seen in 1995's ''Knuckles Chaotix'').
** Since about the time of ''VideoGame/SonicUnleashed'', more recent and/or once-major characters have been set aside in favor of simply having Eggman, Tails, and Sonic. This may be in response to the criticisms for the series' LoadsAndLoadsOfCharacters.
** As of June 2012, the infamous Big the Cat [[http://youtu.be/l_fL0NRDYjw?t=2h2s has also been retired from the series]]. He was already being slowly phased out of the series by that point anyway--his only noteworthy appearances after 2003's ''VideoGame/SonicHeroes'' being in ''VideoGame/SonicChronicles'' and the first ''[[VideoGame/SegaSuperstars Sonic and Sega All-Stars Racing]]'' (and even then, he was removed from the roster in the sequel).
** Several of these characters have remained as recurring characters in the comics, with Mighty being a main/semi-regular cast member since the Chaotix tie-in mini-series and Knuckles' own spin-off, and Nack being a recurring villain as far back as (or even further back as) the "Mecha Madness" super special. [[BrokenBase Fans of the comics are just as outspoken when criticizing these absences from the games that they rival the critics of the series']] LoadsAndLoadsOfCharacters.
* ''[[Franchise/SoulSeries Soul Calibur V]]'' is notable for having a lot of new characters at the expense of losing some old faces, including, rather infamously, popular faces Talim and Zasalamel as well as Rock, who have literally disappeared without a trace. At least Cassandra had her fate told in an artbook and the fate of Seong Mi-Na, Yun-seong and Setsuka were mentioned later on (With Setsuka having been Patroklos' teacher at one point) but Talim, Zasalamel and Rock have seemingly vanished off the face of the earth with no mention whatsoever from artbooks or WordOfGod as to what happened to them, almost as if they never existed. This has contributed to SCV's status as a BaseBreaker amongst the fans.
* ''VideoGame/{{Touhou}}'''s transition from PC-98 to Windows is either a ContinuityReboot or the single largest case of this ever. Only four characters ultimately survived the changeover out of forty or so, losing fairly major characters like [[ArchEnemy Mima]] and [[TalkingAnimal Genji]], though they're still canonally considered the mentors to Marisa and Reimu, respectively.
* ''VideoGame/PacMan'':
** Ms. Pac-Man and just about the entirety of the Pac Family[[note]]which include Pac-Man Jr., Baby Pac-Man, Professor Pac, and the two pets Chomp-Chomp and Sourpuss[[/note]] have been missing for years. With [[WesternAnimation/PacManAndTheGhostlyAdventures the reboot]] they might have been retconned out of existence.
** Any of the ghosts outside of the main four from the original game [[note]]Sue, Funky/Common, Spunky/Grey Common, Kinky, and Orson. Tim from ''Jr. Pac-Man'' is excluded since his game is not considered official.[[/note]] also seemed to vanish.
* In ''Franchise/TheElderScrolls'', General Warhaft. Leader of the Imperial Legion, wrote two of the in-game books on armour and fighting, imprisoned along with the Emperor by Jagar Tharn... but he never is mentioned after ''[[VideoGame/TheElderScrollsArena Arena]]'', except for in the aforementioned books. He goes unheard of in ''[[VideoGame/TheElderScrollsIIDaggerfall Daggerfall]]'', ''Battlespire'' and ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'', and when the player visits the Legion headquarters in ''[[VideoGame/TheElderScrollsIVOblivion Oblivion]]'', he's replaced by Commander Adamus Phillida, with no word on what happened to him or where he is now.
** In a large-scale Chucking, the cities of Sutch, Artemon, and Mir Corrup were mentioned as being in Cyrodiil in several prior games. When ''Oblivion'' comes around, and we actually get to visit Cyrodiil, ''the entire cities are gone''. The developers admitted they never had time to add them into the game (a semi-canonical explanation ''was'' made for Sutch, though - apparently, the city was ceded to Hammerfell as part of the peace settlement following the events of ''Redguard''. Which only left the problem of why Sutch had been implied to have been a part of Cyrodiil after that point, of course).
** The protagonist characters have a semi-enforced and downplayed variant: the following games do acknowledge what happened in the last one, and they do touch upon the character you played, insofar as it would be known to the public, but details that would vary from play-through to play-through are, for the most part, strenuously avoided, presumably to avoid invalidating people's play-throughs.
*** WordOfGod on the events of Skyrim tries to explain this by saying "all the quest chains present in the game happen, but not all are necessarily done by the Dragonborn." This could also be taken as their attitude towards the protagonists in previous games.
* Almost half the kids in the ''VideoGame/BackyardSports'' series. But the series never explains why ''anything'' happens anyway.
* This is, unfortunately, common in ''Franchise/ResidentEvil'':
** Both Barry Burton and Rebecca Chambers in [[VideoGame/ResidentEvil the first game]], discounting both Rebecca being the protagonist of [[VideoGame/ResidentEvil0 the prequel to that game]] and their playable appearances in the Mercenary Reunion mode of ''VideoGame/ResidentEvil5''. Worse yet, Barry is the protagonist of a GaidenGame for the Game Boy Color...which is [[CanonDiscontinuity non-canon]]...
*** [[spoiler:Barry does appear in the ending for ''VideoGame/ResidentEvil3'', as the helicopter pilot rescuing Carlos and Jill.]]
*** Barry is now one of the playable characters, with his own story, in [[VideoGame/ResidentEvilRevelations2 Revelations 2]]. Rebecca, however... [[spoiler: [[FridgeHorror may have been the first victim of Nemesis, since Brad had to know that it was targetting S.T.A.R.S. members]].]]
** Sherry Birkin was originally this in ''VideoGame/ResidentEvil2'', but she now averts this by being a new player character in ''VideoGame/ResidentEvil6''.
** Carlos Olivera in ''VideoGame/ResidentEvil3Nemesis''
** ''VideoGame/ResidentEvil4'': [[MemeticMutation WHERE'S THE]] [[EnsembleDarkhorse MERCHANT?!]]
** Sheva Alomar in the fifth game could become this.
** Anybody in the spinoff games, with ''VideoGame/ResidentEvilOperationRaccoonCity'' taking the cake.
* ''VideoGame/SimonTheSorcerer 3D'' has a strange character called Jar Nin whom you accidentally kill at the beginning of the game. Towards the end of the game it turns out that you have to resurrect him because you need him on your team. But when you do, he does exactly nothing and even vanishes shortly after, never to be seen or mentioned again.
* Not characters ''per se'', but every creature from the Xen borderworld in the first ''VideoGame/HalfLife1'' - apart from the standard headcrabs (and zombies), the barnacles, the Vortigaunts (now as an ally), an ichthyosaur as a cameo, and the leeches ([[BorderPatrol who are now invincible barriers to the ocean]]) - somehow vanished from the cast list before the start of ''VideoGame/HalfLife2''.
** Stranger still, Barney Calhoun seems to be suffering from this as of ''Episode 2''.
** For that matter, with the exclusion of Barney, pretty much every major character from the first game's expansions (Shephard from ''Opposing Force'', Gina and Colette from ''Decay'', and Rosenberg from ''Blue Shift'') disappeared entirely between the first and second game. Considering the circumstances, this could be justified.
* ''Franchise/{{Pokemon}}'' has Agatha, who disappears without a trace in ''[[VideoGame/PokemonGoldAndSilver Gold/Silver/Crystal]] / [[VideoGameRemake HeartGold/SoulSilver]]''. This wouldn't be a problem, since you would think that Agatha could have retired, but the games don't make any further reference to her past in ''[[VideoGame/PokemonRedAndBlue Red and Blue/FireRed and LeafGreen]]''.
* Most characters in the ''VideoGame/WarioLand'' series just vanished without a trace after the original games they were in. Captain Syrup returned in ''The Shake Dimension'', after a ten odd year gap between appearances, but God knows what happened to Rudy the Clown after he returned in ''VideoGame/DrMario 64''...
* ''Franchise/JakAndDaxter'':
** Gol and Maia are the duo's first major baddies, and after their defeat in the first game a return is hinted at by the Green Sage. However, the series decided to go DarkerAndEdgier and thus the rogue Sages were [[{{Pun}} "chucked"]] out.
** [[VideoGame/JakIIRenegade The second game]] introduces us to Brutter, the leader of the local Lurkers who befriends Jak and Daxter. At the end of the game, he seems to be working for Ashelin as captain of the New Krimzon Guard, but he is nowhere to be seen in ''[[VideoGame/Jak3Wastelander Jak 3]]''. Admittedly, Brutter does make a short appearance in the ''Daxter'' spin-off, but since that game is set before ''Jak II'' it doesn't explain what happened to him between ''Jak II'' and ''3''.
** The second game also had the Crocadog, a [[MixAndMatchCritters Mix-and-Match Critter]] that Jak seemingly adopts as his pet in the end. He is never seen or referenced after ''Jak II''.
** Jak's uncle in the first game. While [[spoiler:Jak was born in the future and thus he can't be his real uncle]] it feels a bit weird how after delivering the orbs to him he is never mentioned again. You'd think that he'd care a bit more about Jak's adventuring since he probably raised him.
** [[spoiler:Ottsel Veger]] is adopted by Kleiver as a sidekick, yet vanishes entirely by ''Jak X'' and is never mentioned again. His fate is unknown, but [[MoralEventHorizon hopefully]] [[YouKilledMyFather very]] [[KnightTemplar unpleasant]].
* More or less every single non-Swordian user from ''VideoGame/TalesOfDestiny'' is completely absent from ''Tales of Destiny 2'', except for a brief reference to Mary in one of the first few skits. This was, in retrospect, [[OutOfFocus just a side-effect from what happened to them in the last third of the first game, though]].
* ''VideoGame/{{Ys}}'': Lilia, after being DemotedToExtra, disappears from the series after ''IV'', as well as several other major characters from ''I and II''. Subverted with Dogi, who is oddly absent from ''V'', but returns in ''VI'', as does old man Raba. Also, what happened to Terra between ''VI'' and ''Seven''?
* A handful of the characters from the very first ''VideoGame/{{Street Fighter|I}}'' are nowhere to be found. At first Ryu, Ken, and Sagat were the only ones to return, then the ''[[VideoGame/StreetFighterAlpha Alpha]]'' series brought back Birdie, Gen, and Adon. Eagle made an appearance in ''VideoGame/CapcomVsSNK2MarkOfTheMillennium''. To this day, however, Geki, Retsu, Lee, Mike, and Joe are all but disowned from the series (well, maybe not Mike, who is widely hypothesized to be "[[NoCelebritiesWereHarmed Mike Bison]]"/[[DubNameChange Balrog]]).
** The comics have had some fun with these. Lee reappears in the ''SakuraGanbaru'' manga as an opponent for Sakura, and in UDON's comics, reappears to challenge Fei Long and is stated to be the uncle of Yun and Yang. Also in UDON's comics, Geki attempts to assassinate Gen, and in the Ibuki miniseries, "Geki" is retconned to be the name of a ninja clan, not an individual, which has a rivalry with Ibuki's clan.
** Most of the ''VideoGame/StreetFighterIII'' cast would qualify, too. The popular ones would go on to appear in other ''Street Fighter'' games (Yun, Ibuki, Makoto, Dudley) and crossovers (Alex, Yun, Urien, and Hugo--who is technically not from ''SF III'', but still counts) but most of them were lucky to even appear as cameos or passing mentions in character storylines. Part of the problem, it should be said, is the long lull in Capcom fighting game releases prior to ''VideoGame/StreetFighterIV''.
** The characters who debuted in ''VideoGame/StreetFighterEX'' belong have never appeared in another Street Fighter game outside of the EX series. The fact that the characters are joint-owned by Capcom and developer Arika may have something to do with it (though a few have made the occasional cameo in other Arika games, and the company started work on a game featuring the EX-only cast.)
*** One of the most unusual cases within the EX series was a character called Hayate, a young Japanese swordsman. He appeared as a newcomer in ''EX 2'', but was mysteriously removed from the updated version of the game. The PS1 port returned him to the roster as a secret character, but after that, he never appeared again (and was the only character from ''EX 2'' to not return for ''EX 3''). There was [[UrbanLegendOfZelda a persistent rumour]] that he had been killed off between the two games, but no, he simply vanished entirely without a trace.
**** A potential explanation for Hayate is that Capcom removed the character because they couldn't sell ''EX 2'' in Korea due to that country's hatred of samurai[[note]]The same reason Namco created Arthur, a blond British [[SuspiciouslySpecificDenial totally-not-a-samurai]], to replace Mitsurugi in certain versions of ''Soul Calibur''[[/note]]; he does stay around in another way, as his Super Combos were given to [[AnimatedArmor Garuda]] as his Meteor Combo.
* In ''VisualNovel/ApolloJusticeAceAttorney'', where did all of Phoenix's friends go in the past seven years? The only characters from the first three games that show up are Phoenix, Ema, Payne, and the Judge (and, in flashback, Gumshoe and Mike Meekins).
** Maya is mentioned, as is Mia, just not by name. Phoenix at one point refers to a "kid" he knows who sends him Samurai series videos tapes and he again mentions a "Girl" he once know who Trucy reminds him of. Guy Eldoon, the noodle saleman, even refers to Maya at one point saying that Phoenix used to frequent his noodle stand with "That assisant girl" back when he was an attorney. Examining "Charley" in the office, prompts Apollo into talking about how Phoenix mentioned his "Chief" once.
** Ema also references Edgeworth when informing Apollo that prosecutors should be "simmerous" rather than "glimmerous."
** This is probably done to not spoil any cases from previous games.
* Continuing from that last example, ''VisualNovel/PhoenixWrightAceAttorneyDualDestinies'' brings back some characters from Phoenix's original trilogy and Apollo's game, but plenty of characters are still no-shows: Maya has yet to return, Gumshoe is still nowhere to be seen, Ema is inexplicably absent despite her role in ''Apollo Justice'' (which chronologically takes place the year before ''Dual Destinies''), and even Payne's gone in favor of his newly-introduced younger brother.
** Phoenix does read a letter from Maya (which was delivered by Pearl) in Case 5.
* ''Franchise/MortalKombat'': All of the characters from ''Special Forces'' and ''Mythologies: Sub-Zero'' who haven't appeared in a FightingGame before (Sareena had a playable appearance in a portable version of ''Deadly Alliance'' called ''Tournament Edition'') didn't made the cut for ''Armageddon''.
** Except Sareena's two partners in ''Mythologies''; they appear in Konquest Mode of ''Armageddon'' as minibosses.
** Tremor later resurfaced in playable for the PS Vita release of ''Mortal Kombat (2011)'' due to immense fan demand, however.
* In ''VideoGame/WorldOfWarcraft'', Calia Menethil, ''heir to the throne of Lordaeron'', disappeared without trace shortly before ''VideoGame/WarcraftIII''. It is speculated that she has taken the name of Calia Hastings and is currently working for the Stormwind SI:7 spy agency, but this is based solely on the OneSteveLimit.
** If Calia Hastings was the missing Princess of Lordaeron, she's either dead, or double-dipping in this trope since the destruction of Theramore just prior to ''Mists of Pandaria''.
** A Q&A with ''Warcraft'''s [[WordOfGod creative devs]] had them answer all "where are they now" questions with a general "we have plans and don't want to spoil them" answer.
** In the RPG books, Brann Bronzebeard lampshades this, briefly mentioning that he's not sure where Calia is and that he'll have to look into it.
** Also a large number of [=NPCs=] in ''World of Warcraft: Cataclysm''. Overlaps with NeverFoundTheBody in some cases.
** The black dragon Sabellian, as the only one of his race who doesn't seem to have a problem with the player races, is conspicuously absent from all the events surrounding the return of his father Deathwing, the destruction of the rest of the black dragonflight as incurably corrupted, and the birth of his uncorrupted brother Wrathion. Possibly he decided he wanted no part of the whole thing and just stayed in Outland. It was later confirmed that Sabellian is still alive and Wrathion simply doesn't know about him.
* Kaya Daidouji is a pretty important character in ''VideoGame/RaidouKuzunohaVsTheSoullessArmy''. In the sequel, ''VideoGame/RaidouKuzunohaVsKingAbaddon'', she isn't mentioned once.
** Believed to have moved away from the family mansion in 'King Abaddon'. It is inhabited by ghosts as a side mission.
* Magma is the point-of-view character and saves the planet in ''VideoGame/XMenLegends'' but isn't even mentioned in its sequel.
* Happens to quite a few characters in ''VideoGame/VanguardBandits'' due to the branching paths in the game. A important ally in one path can disappear into the ether on the next.
* ''Franchise/CrashBandicoot'': Crash's girlfriend Tawna is axed after [[VideoGame/CrashBandicoot1996 the first game]], replaced instead by hacker sister Coco. Yes, [[LampshadeHanging apparently, Crash has a little sister that he was never told about]].
** Though Tawna does reappear as a playable character in the DS game ''Crash Boom Bang!''. The game manual states that she's dumped Crash for Pinstripe Potoroo.
* ''VideoGame/LegoIsland'' was hit with this hard. Let's see, we had Captain D. Rom, Enter and Return, the Funbergs, Polly Gone, Studs Linkin, all of the flying Legondos (excluding Jack O'Trades), and the two workers.
* ''VideoGame/DynastyWarriors 6'' was notorious for cutting some of the roster and relegating twenty-four of the remaining forty-one characters to "Free Mode only" (having no Musou Mode storyline and cutscenes, though its [=PS2=] re-release converted six of them to Musou Mode, for a total of twenty-three Musou Mode characters and eighteen Free Mode only), but in ''Dynasty Warriors 7'' when all of them were brought back except Zuo Ci and Pang De. The former was an inconsequential Daoist mystic, but the latter a notable warrior who'd participated in several key battles ''and'' brought his own coffin to his final military campaign ("win or die," literally), only to not be mentioned ''at all'' in the game, which KOEI explained was due to "certain storyline constraints" (namely, that they didn't have room for him in the direction they were taking the story). In a subversion, however, Pang De reappears in ''Xtreme Legends'', which made it look like the trope was a harbinger for his eventual return.
** ''VideoGame/SamuraiWarriors'' has an JustForFun/{{egregious}} example with Goemon Ishikawa, who has never been seen again after the first game. And after the second game, Musashi Miyamoto and Kojiro Sasaki never appeared either. However, along with Zuo Ci, the three are still present in ''VideoGame/WarriorsOrochi''.
* The heroes of ''VideoGame/MightAndMagic 3'' disappeared without the games ever quite explaining how they went off-course, or even if they did. They just... didn't arrive on XEEN, and when they next showed up (in ''Might and Magic 7''), all they said was that they'd been looking for the Ancients for some time. Of course, they ''did'' return, so it isn't a clear-cut example of Chuck Cunningham Syndrome.
* General Vladimir, who was an important supporting character in ''VideoGame/CommandAndConquerRedAlert2'', is nowhere to be seen in ''Yuri's Revenge'', the game's expansion pack.
* Dragon halfling Halfas in ''VideoGame/DragonValor'' is nowhere to seen chapter five, despite the fact that his actions drive the plot of chapter four (either killing the SacrificialLion or cursing the character to die in a month).
* The ''VideoGame/WaveRace'' series has the four races from ''Wave Race 64'' appear... except for Miles Jeter, who just didn't come back without an explanation.
* In ''[[VideoGame/NintendoWars Advance Wars: Dual Strike]]'', Flak and Adder are completely absent from the story, though they are playable after you beat the campaign. This may have been because of how similar they are to newcomers Jugger and Koal, who have actual bearing on the story.
* Loading the first pre-made neighbourhood included in ''VideoGame/TheSims 2'', the player is greeted with a short slide show which informs them that this particular neighbourhood's story picks up twenty-five years after that of the default neighbourhood in the first game. Members or descendants of four of the five original base game families are there (as well as one or two of the families from later expansion packs). But Chris Jones and Melissa Smith (a.k.a. Chris and Melissa Roomies), who were at least as important and popular with the fans as the other characters - they're simply not there, nor do they even turn up in later expansions as some others eventually did.
* ''VideoGame/FinalFantasyVI'': Most of the first half of the game is spent working with the Returners, including the old man Arvis who's the first non-Imperial you speak to and Banon, their leader. [[spoiler: You last see the two of them in the ruins of the Imperial capital, Vector. Kefka's ascension and the destruction of the world might have killed them, but they're simply never seen or mentioned again.]]
* In the ''Franchise/KingdomHearts'' series, we've got a whole world that is permanently retconed out of series: [[{{Disney/Tarzan}} Deep Jungle]]. This is justified, as Disney could no longer secure the rights to the franchise. Considering that it was one of [[TheScrappy the most hated worlds]], no one really called. In the dreams at the beginning of ''VideoGame/KingdomHeartsII'', when [[{{Disney/Aladdin}} Jafar]] mentions that Sora's found a Keyhole, the resulting scene is Sora sealing the one for Agrabah ([[PlotHole after Jafar's defeat]]), when he actually said it after the one for Deep Jungle is sealed.
* Elora from ''Franchise/SpyroTheDragon'' was a major character in ''VideoGame/Spyro2RiptosRage'' but only got a cameo at the end of ''VideoGame/SpyroYearOfTheDragon''. After that she's suspiciously left out of every other title in the "classic" line, aside from popping up on a trading card in ''Spyro Orange'', despite the fact the others (even Bianca) became {{Ascended Extra}}s. There were plans on include her in two games but she was excluded.
* In the ending of the Decepticon version of the DS game for the 2007 ''Film/{{Transformers}}'' movie, the player's last words imply that Megatron is the only Transformer still alive. While all of the Autobots and most of the Decepticons are killed on screen, Brawl is never seen again after he kills Ironhide.
* It has been three games since [[AssassinsCreed Assassin's Creed 3]] (five if you count the two spinoffs of Black Flag), and we still don't have the slightest idea what became of Connor after the end of the American Revolution. The last we see of him is a melancholy postscript with Davy Crockett, and he's barely mentioned at all in either Rogue or Unity. As he's one of [=UbiSoft's=] least popular characters and there are no plans to develop him any further, it's likely we'll never know.
* Tristan and Duke Devlin don't appear in ''VideoGame/YuGiOhNightmareTroubadour'', even though everyone else from the first three seasons does.
* ''VideoGame/SuperSmashBros.'' has a few of these. Most of them were newcomers from ''Melee''.
** The clones, Pichu, Young Link and Roy are gone completely. One of Pichu's costumes was integrated into Pikachu's available costume set, Roy was gone in favor of non-clone Ike. He also just isn't a very popular character in Fire Emblem's own fanbase. Young Link was replaced with Toon Link. Other clones remained, and started getting differentiated.
** Brawl added Snake and Wolf who are also both completely gone. This may make sense for the former, who's series is almost exclusively on competitor platforms and it may have been difficult to secure the rights for him.
** Due to hardware limitations on the 3DS version, the Ice Climbers are gone from ''4'', even for the Wii U version.
** Averted in the case of Mewtwo and Lucas, who not only at least got trophies when they were cut from ''4'' (the former of which also got one in Brawl where he was also missing from) which is more than other cut characters can say, they also were both announced to be DLC characters due to popular demand. Doctor Mario also averts this, having been missing from Brawl but being back to be included in ''4'' from the start.
** [[InvokedTrope Invoked]] by TrollingCreator Creator/MasahiroSakurai and [[DefiedTrope Defied]] when he stated that Zero Suit Samus wouldn't be making the cut in ''4'', only to show footage of her in-game immediately afterwards.
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