List of playable characters, bosses, and other characters in Sonic 3 & Knuckles from the Sonic the Hedgehog series. Bold characters debut in this entry. For the franchise character page, go here.
Characters in Sonic 3 & Knuckles
- Playable Characters: Sonic the Hedgehog, Miles "Tails" Prower, Knuckles the Echidna
- Added in Sonic Origins Plus: Amy Rose
- Bosses: Dr. Ivo ''Eggman'' Robotnik, Knuckles the Echidna, Mecha Sonic Mk. II, Eggrobo
