!!Rin Asogi
A badass immortal P.I. working out of Shinjiku.
* AntiHero: She's a good person at heart, but she has a rather icy personality. Plus, when she [[spoiler:closes the door behind Saya to let her get eaten by various, zombie like creatures]], she proves that, despite being on the side of good, she sure as hell won't forgive you for [[MoralEventHorizon crossing the line]].
* BackFromTheDead: [[spoiler:Or the closest variant for immortals. Her time spore is removed but thanks to Yggdrasil, her body begins regenerating around it.]]
* {{Badass}}: Kinda comes with the territory when you're immortal.
** BadassInANiceSuit
* BiTheWay: Being immortal seems to loosen a person sexuality.
%%* CryCute
%%* DeadpanSnarker
* GoodIsNotNice: Rin is nice, but she won't hesitate to end a bad guys existence in rather wicked ways.
* IdentityAmnesia: [[spoiler: After getting mulched by a jet engine and two decades of regeneration, she loses her memory.]]
* {{Immortality}}: Through FromASingleCell and being TheUndead.
* JekyllAndHyde: Although it's a subversion [[spoiler:when her "bad side" is just Laura impersonating her]].
* JerkWithAHeartOfGold[=/=]{{Kuudere}}: She can be pretty cold and sarcastic, but she's still quite caring towards those close to her.
* MsFanservice: Boy howdy is she.
* PrivateDetective: How she makes her living.

Rin's sidekick and fellow immortal. Works as a hacker.
* BadassBookworm: An immortal hacker. Kind of a requirement.
* BiTheWay: She certainly has a thing for girls after getting a taste for it, but doesn't seem to dislike guys either.
* GirlFriday: For Rin.
* HardDrinkingPartyGirl: And she even holds her liquor better than Rin.
%%* JerkWithAHeartOfGold
%%* PlayfulHacker
* TheSmartGirl: The tech-savvy sidekick.
* TokenMiniMoe: A slight older example but she always looks younger than everyone else she's around.

A sadistic mother-effer who exists to make Rin's life (And any other persons in his way) an utter misery.
* BigBad: Main antagonist of the series.
* BlondGuysAreEvil: Evil right to his core.
%%* TheChessmaster
* {{Expy}}: Of [[{{Devilman}} Ryo Asuka]].
* EvilTastesGood: Just why is he so obsessed with causing as much pain to every immortal he finds? Because their time spores will taste so much ''better'' soaked with the memories of their pain.
* FauxAffablyEvil: He'll put up a cheerful facade if he chooses, but it's just an act that hides an utter psycho underneath.
* FromASingleCell: Just like Rin.
* {{Hermaphrodite}}[=/=]OtherworldlyAndSexuallyAmbiguous: [[spoiler:It is unclear what the hell s/he is, but s/he apparently has two sets of genitalia.]]
* IHaveYouNowMyProudBeauty: Lord help you if you're an immortal.
* KarmicDeath: [[spoiler: He does gain a permanent position with Yggdrasil. [[LaserGuidedKarma By becoming part of it]].]]
%%* ManipulativeBastard
* {{Sadist}}: One enormous understatement...
* SelfMadeOrphan: [[spoiler:Kills his father, Tajimamori]].
* SoftSpokenSadist: Rarely raises his voice, even when he has woman bound in chains.

A gun toting psycho and Rin's arch-nemesis.
* TheDragon: To Apos.
* ProfessionalKiller: Her main occupation.
* PsychoForHire: ''Very'' psycho.
* PsychoLesbian: Again, quite unhinged.
* TakingYouWithMe: [[spoiler: A variation. After being crippled, she has Rin insert her Time Spore into Apos so she can torment him with her memories before dying.]]
* {{We Can Rebuild H|im}}er: [[spoiler:Apos remakes her as cyborg in [[FoeYay Rin's]] image ([[RapeAsDrama which he proceeds to have some fun with]]) and implants a time spore in her as well.]]

A mysterious individual with ties to Rin.
* ChekhovsGunman: [[spoiler:A trait he shares with his descendents.]]
* HeWhoMustNotBeSeen: We don't meet him until the final episode.
* OurAngelsAreDifferent: [[spoiler:The only Angel who has no desire to eat someone. There's a reason for that.]]
* StarCrossedLovers: [[spoiler:With Rin.]]
* ThereCanOnlyBeOne: [[spoiler:And Apos decides that Tajimamori ain't the One [[SelfMadeOrphan anymore.]]]]
* WalkingSpoiler

!!Kouki Maeno
A regular Joe who gets swept into Rin's world.
* AndThenJohnWasAZombie: [[spoiler:To save an immortal, he became an Angel.]]
* {{Deuteragonist}}: Serves as the viewpoint character, when Rin is not it.
* CloningBlues: [[spoiler:Though he gets over it after episode 1.]]
* [[spoiler:KilledOffForReal: Becomes an Angel.]]
* LockedIntoStrangeness: After [[spoiler:attempting suicide and somehow surviving]], he has a permanent spot of miscolored hair.