The protagonist of the game, our heroine is a kind girl who has lost her memories and must retrieve them with the help of Orion. Despite her story and the cause of her amnesia change depending on the route, in all of them she's a first-year university student and a maid at the "Maid to Shitsuji" Café.

->'''Voiced by:''' Creator/KaoriNazuka (anime) (Japanese), Maggie Flecknoe (English)
* AmnesiacHero
* AudienceSurrogate
* BreakTheCutie: [[spoiler: Not only the heroine has to withstand dying in several universes, in Toma's route she's thrown into a cage because supposedly "she'll be safer there".]]
* CanineCompanion: Had a dog named Kuro in Kent's route. [[spoiler: He dies after he's run over by a car, and it was the cause of her fight with Kent.]]
* ChildhoodFriends: With Shin and Toma.
* ExtremeDoormat: In Toma's route, [[spoiler: she's kidnapped, drugged and put into a cage by him; despite everything, she forgives him at the end, since both were in love with each other since the beginning.]]
* FlowerMotifs: She's usually symbolized by flowers. She also wears roses in her hat and her blouse.
* HelloInsertNameHere: In the game.
* IllGirl
* KillTheCutie: The game has ''a lot'' of bad endings, and all of them end with her death.
* {{Meido}}
* NiceHat
* NoNameGiven: In the anime, she doesn't remember her name. In the game it's the only thing she remembers, but it must be chosen by the player.
* TheQuietOne
* ShrinkingViolet
* TheVoiceless: Barely talks in the game, only during choices and a bit at the end of the routes. Her lines aren't voiced either.


The boyfriend figure of the Heart world, Shin is a 17-year-old boy who is studying to get into university. Despite being quite rude, he always tries to do the best for the heroine. In every route (except his own) and the anime he works as a cook at "Maid to Shitsuji".

->'''Voiced by:''' Creator/TetsuyaKakihara (Japanese), Houston Hayes (English)
* DeclarationOfProtection: To the heroine in his route.
* DisappearedDad
* JerkWithAHeartOfGold
* LuminescentBlush: Gets one whenever the heroine does something he finds cute.
* TheRival: With Toma.
* SpotlightStealingSquad: Despite the "true route" being [[spoiler: Ukyo's]], he gets the centre spot (and sometimes he's the sole boy to be featured) in the games' covers.
* {{Tsundere}}


The boyfriend figure of the Spade world, Ikki is a 22-year-old university student in his fourth year. The most popular butler at "Maid to Shitsuji", he even has a fanclub of girls who visit him everyday.

->'''Voiced by:''' Creator/KisshoTaniyama (Japanese), Creator/BlakeShepard (English)
* AffectionateNickname: Is called "Ikkyu" by Kent.
* BeCarefulWhatYouWishFor: [[spoiler: As a child, he wished to be popular. As a result, any woman who looks him in the eye falls in love with him.]]
* TheCasanova
* ChickMagnet
* CoolShades: Wears them to try to keep his fangirls away.
* CurtainsMatchTheWindow
* EverybodyCallsHimBarkeep: His real name is Ikkyou, but everyone goes by Ikki.
* HairDecorations: He wears a spade-shaped clip.
* ILoveYouBecauseICantControlYou: In his route. See {{Be Careful What You Wish For}} entry above.
* InstantFanclub
* LadyKillerInLove: In his route.
* TechnicolourEyes: In the anime, his eyes are switched to a weird mixture of pink and blue.
* VitriolicBestBuds: With Kent.


The boyfriend figure of the Clover world, Kent is 25 years old and the heroine's tutor. He likes math problems and believes everything can be resolved by logic.

->'''Voiced by:''' Creator/AkiraIshida (Japanese), Tyler Galindo (English)
* {{Adorkable}}
* AffectionateNickname: Is called "Ken" by Ikki.
* TheBigGuy: He's considerably taller than the other guys.
* IKissYourHand: One of his [=CGs=] in the first game.
* {{Megane}}
* NoSocialSkills: He has little clue of how to talk normally to people, as he always thinks through cold logic.
* SmartPeopleWearGlasses: He's the tutor of the heroine's study club and is shown to like puzzles and mathematic problems.
* TooManyBelts: [[http://img2.wikia.nocookie.net/__cb20130115223718/amnesia-anime/images/6/63/Amnesia_kent.png His usual outfit.]]
* VitriolicBestBuds: With Ikki.


The boyfriend figure of the Diamond world, Toma is a 20-year-old university student at his second year. He's also a butler at "Maid to Shitsuji", and cares deeply about the heroine.

->'''Voiced by:''' Creator/SatoshiHino (Japanese), Creator/ChrisAyres (English)
* [[spoiler:BlondGuysAreEvil]]
* ChildhoodFriends: With Shin and the heroine.
* CurtainsMatchTheWindow
* [[spoiler: GildedCage: He thinks the cage he forces the heroine to live in is this: it's full of cute plushies he's specially bought for her, and he stills lets her go to the bathroom and wash herself as long as he keeps an eye on her.]]
* HairDecorations: Wears a black headband.
* [[spoiler:{{Yandere}}]]


The boyfriend figure of the Joker world. A 25-year-old photographer who seems to know the heroine, but remains distant in all the other routes.

->'''Voiced by:''' Creator/KoukiMiyata (Japanese), Patrick Poole (English)
* CameraFiend
* CurtainsMatchTheWindow
* BeCarefulWhatYouWishFor:[[spoiler: He made a wish to (Orion's superior) Neil to save the Heroine's from death and for him to be able to be with her again at the cost of her not remembering him. The problem is that even if he [[IWantMyBelovedToBeHappy lets her be happy with another man]], the wish cannot be fulfilled and Ukyo remembers every world the Heroine dies by his hand or fell in love with another man and dies in her place because their existence in the same timeline is an anomaly.]]
* EarnYourHappyEnding: [[spoiler: In his route, Neil leaves his body and grants Ukyo and the heroine a happy ending together.]]
* GroundhogPeggySue: [[spoiler: This is done by Neil as he needed Ukyo's wish to come true to gain back his powers after the conditions were fulfilled.]]
* ImportantHaircut: [[spoiler: Cuts his hair in the Wedding segment in ''CROWD''.]]
* IWantMyBelovedToBeHappy: In every other route except his own, [[spoiler: he dies to let the heroine have her happy ending with another man.]]
* JekyllAndHyde: [[spoiler:Ukyo, as a side effect of going through so many worlds where either he or the heroine died. His Hyde personality tries to constantly kill the heroine, but even then the personality still admitted he loves her.]]
* LongHairedPrettyBoy
* NiceHat
* SecretCharacter: His route is unlocked after finishing the other four. However, he appears in all of them as a side character.
* StarCrossedLovers: [[spoiler: Ukyo and the Heroine at a cosmic definition. One of them has to die as neither of them are suppose to exist together after the Heroine is fated to die from the injuries she sustained in her university's fire. Luckily, Ukyo's wish to Neil was granted when the Heroine survived after her fated death day in their original world and [[EarnYourHappyEnding was able to be with Ukyo.]]]]
* WalkingSpoiler: He was one of the major reasons why the Heroine has amnesia.


A spirit from the dream world who can only be seen and heard by the heroine. He thinks it's his fault that she lost her memories, so he helps her in that quest.

->'''Voiced by:''' Creator/HiromiIgarashi (Japanese), Creator/ShannonEmerick (English)
* AscendedExtra: Gets his own route in ''LATER''.
* AudienceSurrogate: Even more than the heroine!
* GenreSavvy: Oh so much.
* HornedHumanoid
* [[spoiler: MissionFromGod: He didn't meet the heroine by chance, as he was given the quest of finding his creator, the leader of the spirits Neil.]]
* NonHumanSidekick: Despite his human appearance, he's actually an spirit from the dream world.
* SpiritAdvisor


The heroine's best friend, a lively university student who studies at the same university as the heroine. She also works as a maid at "Maid to Shitsuji".

->'''Voiced by:''' Satomi Moriya (Japanese), Allison Sumrall (English)
* AmbiguouslyGay: At least in the anime. She visits the café in a route where she isn't an employee to flirt with the Heroine, seems a little betrayed when she likes Ikki (and may subtly be trying to influence her away from him despite not showing any interest in him herself, unlike Mine), and is really happy about the high female to male ratio on one of the trips. Some viewers who never got to play the game speculated that she may have been a GayOption.
* BookDumb: She seems to struggle with writing her report for university.
* GenkiGirl
* HairDecorations: Wears two flower hair-clips.
* {{Meido}}
* PassionateSportsGirl: She's in several sport clubs.
* TomboyAndGirlyGirl: The tomboy to Mine's girly girl.
* TomboyishPonytail


A co-worker of the heroine at "Meido to Shitsuji" and a bit younger than her. She has a bubbly personality and is also a member of Ikki's fanclub.

->'''Voiced by:''' Kana Akutsu (Japanese), Molly Searcy (English)
* CurtainsMatchTheWindow
* HairDecorations: Wears a butterfly decoration in her bun.
* LongHairIsFeminine
* {{Meido}}
* PinkMeansFeminine
* TomboyAndGirlyGirl: The girly girl to Sawa's tomboy.
* ValleyGirl: Talks like this in the anime's English dub.


The boss at Meido to Shitsuji. His most remarkable feature is that his personality changes on each route.

->'''Voiced by:''' Hidenori Takahashi (Japanese), Jay Hickman (English)
* AscendedExtra: Got his own route in ''LATER''.
* TheCasanova: In Shin's route.
* HairTriggerTemper: Ikki's route.
* {{Megane}}
* TheQuietOne: Kent's route.
* ReasonableAuthorityFigure: Toma's route.


She is the head of Ikki's fanclub. A sarcastic and aristocratic woman, her obsessive love for Ikki puts her at odds with the heroine.

->'''Voiced by:''' Yoshida Seiko (Japanese)
* AlphaBitch: [[spoiler: She becomes a {{Lovable Alpha Bitch}} in Ukyo's world thanks to being friends with the heroine.]]
* BlondesAreEvil
* CurtainsMatchTheWindow
* NiceHat
* {{Ojou}}: Implied to be one.