Biological Weapons Solve Everything
The convenient and easy Final Solution.
Just like Genetic Engineering Is the New Nuke, Biological/Chemical outbreaks are the new Nuke 'em. So why choose this above Deus Ex Nukina? Several reasons. While nuclear weapons are highly destructive and devastating to an enemy, a Nuclear War would probably cause more problems than it solved (perpetual winter, radiation, etc.), and thanks to the Cold War, the general public is very familiar with the theoretical effects of a nuclear war. On the other hand, biological weapons are so variable that they can basically do whatever the plot requires. So, if the heroes are experiencing their Darkest Hour, and the end looms near, this is a simple and effective way to tip-toe around a situation where Only the Author Can Save Them Now. Likewise, if you want to demonstrate how depraved your villain is, you can certainly show victims of The Plague dying in slow and horrible ways, and punctuate it with mounds of burning bodies. It can go by many names: The "Virus", The "Plague", The "Cure", The "Cleansing", etc, but it fits the same criteria:
- It targets only living things. Infrastructure and biospheres are left untouched.
- It will completely destroy the enemy ranks, or at least decimate them to the point that they are not a significant threat.
- It can be spread across the entire kingdom, continent, planet, universe, etc.
- It has a half-life long enough or communicability rapid enough that it's nigh-impossible to escape.
- (Optional) It will target the enemy and only the enemy, leaving the deploying army free from consequence.
- In League of Extraordinary Gentlemen it is revealed that the bacteria which killed the martians during the events of War of the Worlds (see Literature below) was in fact a hybrid of Anthrax and Streptococcus developed by Dr. Moreau while working for the British Military.
- Failed spectacularly in Serenity. The Alliance attempted to use an engineered gas to make the violent populace very docile. The gas worked too well: most of the population became so apathetic that they just laid down and died. The others became hyper-violent berserkers, known as the Reavers.
- The crux of the third and final Blade film is the use of a virus that will kill all vampires everywhere, seemingly instantaneously.
- A subversion in Animorphs: the Andalites tried to do this to prevent the Yeerks from enslaving the Hork-Bajir race (by way of a virus that only affected the Hork-Bajir), but eventually failed.
- The War of the Worlds. In H.G. Wells's classic novel, Earth's bacteria do in the aliens. This is kept in most adaptations, from radio to the 1950's movie. Subverted at first in the 80s TV show that just had the aliens in hibernation. Later one of the characters develops a bacteria to kill off the aliens for good.
- In Edward Willett's "Marseguro" a colony of genetically engineered humans called "Selkies" is invaded by the religious fanatics who rule the rest of human space. The Selkies unleash a plague designed not to harm them and vaccinate the baseline human colonists. The invaders die but the baseline who drew them there in the first place was vaccinated and an unknowing carrier, and he made it back to Earth where it kills a large chunk of the planet. The sequel "Terra Insegura" covers a Selkie mission to bring the vaccine to Earth.
- The Aschen from Stargate SG-1 use super bacteria as a means of destroying any opposition on any newly conquered planets. Once the weapon has killed all infustructer they come in and make themselves look like heroes.
- An erstwhile Alliance officer on Firefly made his fortune using biological weapons to depopulate communities, then he looted their untouched valuables.
- Used in the 7th season of Supernatural by the Leviathans against the other monsters. they used a special chemical in fast food that would make the body's of humans who ate it to be deadly to all monster species, and this is a series where every on is a Humanitarian.
- God has done this a few times.
- Warhammer 40K. Virus bombing is one of the ways Exterminatus (destroying a planet that has succumbed to The Corruption or cannot be saved) can be carried out. As it destroys all life (and eventually, the atmosphere), its use is rather limited.
- The first Halo trilogy can be loosely interpreted to end this way. The eponymous Halos are installations which can wipe out all life within a certain radius, meant to "starve" The Flood. The Halos aren't biological weapons themselves, but they're clearly built to target certain forms of life (plants and most animals are left untouched, but anything sapient is toast).
- In Resistance, an eleventh-hour cure is used to defeat the Chimaera and end a war that, technically, humanity had already lost years ago.
- An eleventh-hour cure is also used in Gears of War to destroy both the Locust and the Lambent.
- Subverted in Metroid. The Chozo created the eponymous Metroids as a biological weapon to control the rampant Parasite X on planet SR-388, which could have threatened the entire galaxy if left unchecked. Later, other races discovered the Metroid and the creatures began to spread across the galaxy, proving to be an even worse threat than Parasite X. Then, when Samus eradicated the Metroid, Parasite X came back stronger than ever.
- Played with in the Multiple Endings of Mass Effect 3.
- In the Destroy ending, the trope is inverted, with the final weapon destroying all synthetic life, including the friendly ones, and leaving the organic life alone.
- In the Control ending, only the leader of the villains is affected, with the Hive Mind now being controlled by the main character.
- In the Synthesis ending, both organic and synthetic life are combined into one hybrid race, making the war completely irrelevant.
- The original Sword of the Stars stated that the Liir rebelled against the Suul'ka by using a bioweapon to wipe them out. Given the species' adeptness with Synthetic Plagues everyone assumed that the bioweapon was one. Until the sequel revealed the true nature of the Suul'ka and the "bioweapon" used to destroy them, and that seven of them survived.
- Star Fox Assault concluded with the heroes attacking the Aparoid queen with a electronic virus intended to induce apoptosis in their biological components. Though she is able to suppress it somehow until you finish killing her with conventional weapons.
- Genocide Man takes place after several extremist groups used open-source biotechnology to kill billions. The titular Genocide Project is an international law enforcement agency that uses targeted plagues to wipe out "genetic deviants" and their creators.
- Family Guy: Stewie and Bertram end up in a playground war which ends when Bertram infects Stewie's side with Chicken Pox.
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