We are presented with a character that is in some way built to
defy the audience's efforts to sympathize. When this occurs, it is no surprise that this character is served up as a murder victim, or some tragic misfortune. Sometimes this is done in such an anvilicious manner that feeling of crass manipulation may be warranted.
Or the victim has been given the role as the mcguffin, created to get the primary actors into action, and never referenced again. In such a case it would make sense that the audience should waste no time thinking about that poor woman
hit by a bus or strangled in her bed. Because the murderer and the hero are the actual stars.