When Mystery Fiction meets either Historical Fiction or Period Piece—a mystery set in historical time. This enables the work to draw notice from both aficionados of mysteries and of historical fiction, and the attention to detail that is required in a good mystery can be put to good use in an environment that is both familiar and foreign at the same time. At the same time, this makes good historical mysteries into a very hard genre to master—both historical and mystery fiction are noted as very demanding in the research needed. One of the challenges is that is often forces the detective to use the skill and assumptions of his time period, rather than modern investigative techniques. In settings where professional detectives would be anachronistic, the investigator is often a Amateur Sleuth.
- The Black Dahlia (2006) is a fictionalized tale based on the real-life 1947 Elizabeth Short murder. It was adapted from a novel by James Ellroy.
- Chinatown and it's sequel The Two Jakes take place in the 30's near LA.
- The Film Of The Book of The Name of the Rose (1986) has Sean Connery as William of Baskerville, a monk investigating mysterious deaths in a fourteenth-century abbey.
- L.A. Confidential is a mystery that takes place in the 50's Los Angeles.
- Cadfael is a TV adaptation of the Brother Cadfael book series.
- In BBC America's 2012 Copper Kevin Corcoran is an Irish immigrant living in the Five Points neighborhood of New York City during the 1860s. He returns from fighting in the American Civil War to find that his daughter is dead and his wife has disappeared. Robert Morehouse, Corcoran's former commanding officer, uses his family's connections to arrange for Corcoran to be appointed a detective in the New York Police Department.
- Foyle's War is British Series about a Detective Chief Superintendent Christopher Foyle. It is set during World War II.
- David Liss's A Conspiracy of Paper, is the first of a series of novels about Benjamin Weaver, an ex-boxer and thief-taker living in the London of the early 1720's. The mysteries revolve around historical subjects such as the South Sea Bubble and the General Election of 1722.
- The Amelia Peabody series blends mystery, romance, and comedy in its stories about crime solving Egyptologists. The series spans a thirty-eight-year period from 1884 to 1923, with most of the stories taking place in Egypt.
- The American Girls series had a spinoff line actually called "American Girls History Mysteries" featuring characters unconnected to their main lines, but having the same little section about the historical part in the back. The main lines have spin off mysteries too.
- Andrew Pepper's A Pyke Mystery series features the titular character as a Bow Street Runner turned private investigator, who works in the 1840's, at the time when the new railways are opening up Britain as never before.
- The Aristotle Detective series by Margaret Doody has the historic philosopher Creator/Aristotle help his fictional student Stephanous solve mysteries and navigate Athenian politics during the age of Alexander the Great.
- The Benjamin January books by Barbara Hambly tells the story of a free man of color (also the title of the first book) who investigates crime in the city of New Orleans of the 1830s, between working as a pianist and a surgeon.
- The Ben Snow series by Edward D. Hoch is a series of American Old West mysteries set around the turn of the 20th century. These tales are carefully researched historical pieces, sometimes including real historical characters such as Butch Cassidy.
- The Brother Cadfael series is about a medieval British monk who frequently ends up investigating crimes.
- Death Comes as the End, by Agatha Christie, is set in Egypt circa 2000 BC.
- Detectives in Togas is a Kid Detective series set in Ancient Rome.
- The Elizabethan Theatre series by Edward Marston, featuring Nicholas Bracewell, stage manager (and amateur detective) for one of Elizabethan London leading theatrical companies.
- The Enola Holmes Mysteries stars Enola Holmes as the 14 year old kid sister of Sherlock Holmes. While the original Sherlock Holmes stories would not be considered historical fiction because they are contemporary to the time they were written, these stories were written in the 21st century.
- The Erast Fandorin cycle of novels, set in Imperial Russia, and sometimes Imperial Japan.
- Alan Gordon's Fools Guild series, which follows Feste, the jester from Shakespeare's Twelfth Night.
- The Gareth And Gwen series in Medieval Wales
- Judge Dee is a series of novels about a Tang dynasty official in 7th century AD China, who solves various mysteries ranging from domestic crimes to conspiracies against the throne.
- Groucho Marx, Master Detective and its sequels by Robert Goulart, which portrays Grouch as an Amateur Sleuth in 1930s Hollywood.
- The Marcus Didius Falco series, set in ancient Rome at the time of the Emperor Vespasian.
- The Monk Series by Ann Perry is set in Victorian London in the 1850's though the 1860's. The title character, William Monk, is at various times in the series a police detective or a Private Detective.
- The Name of the Rose by Umberto Eco is the story of the monk William with his novice sidekick Adso as they visit a famous monastery and investigate several mysterious deaths there.
- Ann Perry's Pitt Series is set in Victorian London in the 1880's though the 1890's. Thomas Pitt starts out as an ordinary Scotland Yard Inspector at the famous Bow Street police station and eventually works his way up to the head of Special Branch. His wife, Charlotte Pitt, is a well born lady who sometimes uses her social status to assist her husband by investigating parts of upper-class female society that are not easily accessible by police officers.
- The Roman Mysteries is a Kid Detective series by Caroline Lawrence, set in The Roman Empire.
- The Roman Mystery Scrolls is a sequel to The Roman Mysteries, intended for younger readers.
- Roma Sub Rosa is a Detective Fiction series by Steven Saylor, about a Private Detective called "Gordianus the Finder." Like the SPQR Series, it takes place during the final years of The Roman Republic.
- Simon Hawke's Shakespeare And Smythe mystery series includes A Mystery of Errors, The Slaying of the Shrew, Much Ado About Murder, and The Merchant of Vengeance. They're all about William Shakespeare and a friend solving mysteries which bear strong parallels to Shakespeare's.
- The SPQR Series by John Maddox Roberts follows the sleuthing and political career of Senator Decius Caecilius Metellus during the final years of the The Roman Republic.
- The Western Mysteries, also known as The PK Pinkerton Mysteries, is a Kid Detective series by Caroline Lawrence set the The Wild West.
- The Yashim Series by Jason Goodwin is set in Istanbul during the 1830's.
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