| 1 | * HilariousInHindsight: |
| 2 | ** The very same episode [[VerySpecialEpisode that tells us homophobia is wrong]] has a plot which ends with Doogie being informed by his girlfriend that "[his] charm lies in ''not'' being one of the guys". |
| 3 | ** Also Doogie attempting to drink scotch and smoke a cigar, but getting ill. Years and years later on ''Series/HowIMetYourMother'', he's playing Barney Stinson, who smokes cigars and is a functional alcoholic. |
| 4 | ** In the episode "That's What Friends Are For", Vinnie reminisces about the Halloween both he and Doogie went as ComicBook/SpiderMan. Neil Patrick Harris would later [[WesternAnimation/SpiderManTheNewAnimatedSeries voice the famous webcrawler.]] |
| 5 | * MemeticMutation: To this day, any person who is established and successful in a career at a much younger age than is typical is referred to as a "Doogie Howser-type". |
| 6 | * RetroactiveRecognition: |
| 7 | ** That reporter from "Love Means Constantly Having to Say You're Sorry"? That's ''[[VideoGame/MetalGearSolid Otacon]].'' |
| 8 | ** Creator/MaxCasella, who plays Doogie's best friend Vinnie, would go onto achieve fame for his roles as Benny Fazio in ''Series/TheSopranos'' and Daxter in the ''VideoGame/JakAndDaxter'' series and [[VideoGame/PlayStationAllStarsBattleRoyale beyond]]. |
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