History Trivia / OsmosisJones

** According to [[https://www.flickr.com/photos/36185771@N06/8044849561/in/photostream/ this long series of pictures]] (continue by clicking right), had the film not bombed, there would have been a surge of merchandise based off the movie such as T-shirts, key chains, and oddly enough, a snot slingshot that shoots fake boogers.

** In an early script draft, Frank was a construction worker instead of a Zoo keeper.

** In an early script draft, Frank was a construction worker.

* ColbertBump: The film received a major resurgence 20 years later, Due to the ''UsefulNotes/COVID19Pandemic'', Mostly because the main villain is a virus that has franks body assume it's a common cold until it become fatal.

* ColbertBump: The film received a major resurgence 20 years later, Due to the ''UsefulNotes/COVID19Pandemic''.

* ColbertBump: The film received a major resurgence 20 years later, Due to the ''COVID19Pandemic''.

* StarDerailingRole: This movie and ''Pootie Tang'' did Creator/ChrisRock's acting career no favors. Bar the ''WesternAnimation/{{Madagascar}}'' franchise, most of his acting roles since have been in films he's conceived and directed himself.

* OldShame: In a 2017 interview with Hannibal Buress, Chris Rock admitted that the film didn't turn out as well as he'd hoped and believed that, in hindsight, it would have worked better as a fully live-action movie, as the Farrelly brothers' style of comedy doesn't really lend itself well to animation.

* AccidentallyCorrectWriting: As [[https://i.kym-cdn.com/photos/images/original/001/455/495/00b.jpg this post]] points out, [[Franchise/{{Pokemon}} Pikachu]] makes a split-second cameo in a crowd scene. There [[AluminumChristmasTrees actually is a protein]] called [[https://en.wikipedia.org/wiki/Pikachurin Pikachurin]], but it wouldn't be discovered [[HilariousInHindsight until 2008, 7 years after the film premiered.]]

* OldShame: In a 2017 interview with Hannibal Buress, Chris Rock admitted that the film didn't turn out as well as he'd hoped and that, in hindsight, it would have worked better as a fully live-action movie, as the Farrelly brothers' style of comedy doesn't really lend itself well to animation.

* TroubledProduction: Surprisingly ([[WesternAnimation/QuestForCamelot given]] [[WesternAnimation/TheIronGiant their]] [[Film/LooneyTunesBackInAction track record]]) not the case for the animated sequences (that were finished ahead of schedule) but more for the live-action sequences which had no director or a star actor and it took a considerable amount of time acquiring both, until fairly late into production when Bill Murray was cast and the Farrelly brothers stepped in to direct. This was also one of the reasons the film was delayed from its summer 2000 release to the summer of next year.

* TroubledProduction: Surprisingly [[WesternAnimation/QuestForCamelot given]] [[WesternAnimation/TheIronGiant their]] [[Film/LooneyTunesBackInAction track record]] not the case for the animated sequences (that were finished ahead of schedule) but for the live-action sequences which had no director or a star actor and it took a considerable amount of time acquiring both, until fairly late into production when Bill Murray was cast and the Farrelly brothers stepped in to direct. This was also one of the reasons the film was delayed from its summer 2000 release to the summer of next year.

* TroubledProduction: Not the case for the animated sequences (that were finished ahead of schedule) but for the live-action sequences which had no director or a star actor and it took a considerable amount of time acquiring both, until fairly late into production when Bill Murray was cast and the Farrelly brothers stepped in to direct. This was also one of the reasons the film was delayed from its summer 2000 release to the summer of next year.

** After this movie the Farrelly brothers were going to direct an adult comedy film Party Animals for [[Creator/TwentiethCenturyStudios 20th Century Fox]]based on the novel Frisco Pigeon Mambo by C. D. Payne with Creator/SethMacFarlane as the head writer but due to the [[BoxOfficeBomb box-office failure]] of this film the idea was scrapped.

* BoxOfficeBomb: With a gross of $14,026,418 against a $75m budget, ''Osmosis Jones'' was one of the more expensive bombers from 2001. Fortunately, it recouped its losses on home video and WB even allowed its [[WesternAnimation/OzzyAndDrix spin-off TV series]] to happen.

** After this movie the Farrelly brothers were going to direct an adult comedy film Party Animals for Creator/TwentiethCenturyStudios based on the novel Frisco Pigeon Mambo by C. D. Payne with Creator/SethMacFarlane as the head writer but due to the [[BoxOfficeBomb box-office failure]] of this film the idea was scrapped.

* TroubledProduction: Not the case for the animated sequences (that were finished ahead of schedule) but for the live-action sequences which had no director or a star actor and it took a considerable amount of time acquiring both, until fairly late into production when Bill Murry was cast and the Farrelly brothers stepped in to direct. This was also one of the reasons the film was delayed from its summer 2000 release to the summer of next year.

** After this movie the Farrelly brothers were going to direct an adult comedy film Party Animals based on the novel Frisco Pigeon Mambo by C. D. Payne with Creator/SethMacFarlane as the head writer but due to the [[BoxOfficeBomb box-office failure]] of this film the idea was scrapped.

* {{Defictionalization}}: There's a throwaway line about the "National Chicken Wing Festival" in Buffalo, New York. There was no such festival at the time the film was made, but [[http://www.buffalowing.com/ now...]]

* TroubledProduction: Not the case for the animated sequences (that were finished ahead of schedule) but for the live-action sequences, The live-action sequences had no director or a star actor and it took a considerable amount of time acquiring both, until fairly late into production when Bill Murry was cast and the Farrelly brothers stepped in to direct. This was also one of the reasons the film was delayed from its summer 2000 release to the summer of next year.

* TroubledProduction: Not the case for the animated sequences but for the live-action sequences, The live-action sequences had no director or a star actor and it took a considerable amount of time acquiring both untill fairly late into production when Bill Murry was cast and the Farrelly brothers stepped in to direct.

* VindicatedByCable: It didn't do so well in the box office, but its become well-known thanks to home releases and cable reruns.

* BoxOfficeBomb: With a gross of $14,026,418 against a $75m budget, ''Osmosis Jones'' was one of the more expensive bombers from 2001. Fortunately, it recouped its losses on home video and WB even allowed [[WesternAnimation/OzzyAndDrix its spin-off TV series]] to happen.

* BoxOfficeBomb: With a gross of $14,026,418 against a $75m budget, ''Osmosis Jones'' was one of the more expensive bombers from 2001. Fortunately, it recouped its losses on home video and WB even allowed it TV spin off, WesternAnimation/OzzyAndDrix, to happen.

* BoxOfficeBomb: With a gross of $14,026,418 against a $75m budget, ''Osmosis Jones'' was one of the more expensive bombers from 2001. Fortunately, it recouped its loses on home video and WB even allowed it TV spin off.

* BeamMeUpScotty For reasons unknown, some people associate the phrase "ladies and germs" with this movie.

* ExecutiveMeddling: The movie was originally planned to be PG-13, but almost all of the swearing, a scene of Ozzy visiting sperm cells, and several more violent scenes were cut to be more kid friendly. This is considered by fans to be '''''the worst''''' decision made in production. Some have questioned on what the movie [[WhatCouldHaveBeen would have been]] if it was PG-13. Some have believed that Warner Bros had trouble on deciding to market this as an animated comedy for adults or an animated kids' movie.

* OldShame: Not quite shame, but in a 2017 podcast interview with Hannibal Buress, Chris Rock admitted that it didn't turn out as well as he'd hoped. He also said that in hindsight, it would have worked better as a live-action movie, as the Farrelly brothers' style of comedy doesn't really lend itself well to animation.

* StarDerailingRole: This movie and ''Pootie Tang'' did Creator/ChrisRock's acting career no favors until ''WesternAnimation/{{Madagascar}}''. Most of his roles in-between have been in films he's conceived and directed himself.