History Main / WeaksauceWeakness

* In ''Batman'' story ''Fanfic/DanceWithTheDemons'', Catwoman gets shot with a poisoned dart, and ComicBook/GreenLantern's Power Ring can't extract the poison out of her body. Hal Jordan glumly reckons some of its components must be yellow-colored.[[note]]Green Lantern's greatest weakness is the color yellow and, by extension, the Yellow Lanterns. He was also weak to wood, but in that case it was forced on him for being drunk with power.[[/note]]

* In ''Batman'' story ''Fanfic/DanceWithTheDemons'', Catwoman gets shot with a poisoned dart, and ComicBook/GreenLantern's Power Ring can't extract the poison out of her body. Hal Jordan glumly reckons some of its components must be yellow-colored.[[note]]Green Lantern's greatest weakness is the color yellow and, by extension, the Yellow Lanterns. He's also weak to wood, but in that case it's because he ''thinks'' his powers don't work on wood rather than him ''actually'' being weak to it.[[/note]]

* In ''Batman'' story ''Fanfic/DanceWithTheDemons'', Catwoman gets shot with a poisoned dart, and ComicBook/GreenLantern's Power Ring can't extract the poison out of her body. Hal Jordan glumly reckons some of its components must be yellow-colored.[[note]]Green Lantern's greatest weakness is the color yellow. He's also weak to wood.[[/note]]

* Crocodiles. Easily one of nature's deadliest predators, incredibly hardy and adaptable, can heal from ''torn off limbs'' and have remained virtually unchanged since the age of the dinosaurs since their design was perfectly adaptable to weather through several mass extinctions. But a croc's biggest, most pathetic weakness? While their jaw-closing muscles are incredibly strong and capable of ripping a zebra's leg clean off... their ''jaw-opening'' muscles are surprisingly weak, able to be held shut by a thick rubber band, a roll of tape, or even by human hands. There's at least one known instance of a regular old ''crab'' just pincering a crocodile's jaws shut until it could run off safely It's almost as if evolution found out crocodiles were too overpowered and decided to give them at least ''one'' weakness.

* Crocodiles. Easily one of nature's deadliest predators, incredibly hardy and adaptable, can heal from ''torn off limbs'' and have remained virtually unchanged since the age of the dinosaurs since their design was perfectly adaptable to weather through several mass extinctions. But a croc's biggest, most pathetic weakness? While their jaw-closing muscles are incredibly strong and capable of ripping a zebra's leg clean off... their ''jaw-opening'' muscles are surprisingly weak, able to be held shut by a thick rubber band, a roll of tape, or even by human hands. It's almost as if evolution found out crocodiles were too overpowered and decided to give them at least ''one'' weakness.

* In ''Batman'' story ''Fanfic/DanceWithTheDemons'', Catwoman gets shot with a poisoned dart, and ComicBook/GreenLantern's Power Ring can't extract the poison out of her body. Hal Jordan glumly reckons some of its components must be yellow-colored.

* ''Fanfic/FalloutEquestria'': Littlepip finds evidence of one of the megaspells Twilight Sparkle created during the war, an epic defensive spell that could protect against any attack. The problem? It only works when it's ''sunny''. Even in a world where [[PaintingTheFrostOnWindows the weather is created by ponies]], that's a glaring flaw; the enemy could just wait until the ponies brought some rain clouds in and attack then. By the time of the story, the Pegasus Enclave keeps the Wasteland constantly covered in clouds, meaning it's never an option at all.

* Allergies, especially if the allergen is relatively common. Nuts, animals, shellfish, ''bananas''...in the case of peanut allergies, some cases are so severe that people could be in serious danger just by being in the same ''room'' as peanuts. Some people suffer from [[http://en.wikipedia.org/wiki/Aquagenic_urticaria Aquagenic Urticaria]] (water allergy). That's right, there's people who were unfortunate enough to be born allergic to a substance they can't live without. It's technically not an allergy, but that doesn't make it any better. Any moisture build up on their skin aggravates the condition, so they must carry umbrellas with them at all times, avoid heavy clothing/exercise to prevent sweating and prefer to remain indoors in well ventilated surroundings. For all their precautions, though, they still have to [[FailureIsTheOnlyOption wash themselves with water regularly]].

* Crocodiles. Easily one of nature's deadliest predators, incredibly hardy and adaptable, can heal from ''torn off limbs'' and have remained virtually unchanged since the age of the dinosaurs since their design was perfectly adaptable to weather through several mass extinctions. But a croc's biggest, most pathetic weakness? While their jaw-closing muscles are incredibly strong and capable of ripping a zebra's leg clean off...their ''jaw-opening'' muscles are surprisingly weak, able to be held shut by a thick rubber band, a roll of tape, or even by human hands. It's almost as if evolution found out crocodiles were too overpowered and decided to give them at least ''one'' weakness.

* Programming/coding. Just one missing or extra symbol is enough to make your program fail. Either it will fail at compile time, in which case most compilers will at least helpfully (or not) point out the mistake...or it compiles, only for it to execute in ways you did not intend, and you look through hundreds, maybe thousands, of lines of code to see what you did wrong, and then plant your palm on your forehead because you had an extra semicolon at line 500.

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* ElephantsAreScaredOfMice. At least in cartoons. The scientific jury is still undecided whether this has a sound real-life basis or whether it is just an {{Urban Legend|s}}. ''Series/{{Mythbusters}}'' tested it and found it confirmed: elephants will actively avoid mice if at all possible. Though it's not specifically mice so much as it is wariness at something smaller than an elephant's poor eyesight can reliably identify, to them it could be a snake or something else potentially threatening-the Mythbusters test was done by suddenly revealing white domestic mice to wild elephants, who would have only ever experienced a sudden flash of white color low to the ground as the warning signal of a disturbed cobra. They could also simply be aware of their surroundings and give the small quick moving creature a wide berth to avoid stepping on it.

* In folk tradition, salt is often used to repel evil. It was said a circle of salt could protect one from witches, that salt over your doorstep would ward off ghosts and evil spirit. Salt was often seen as a symbol of purity, especially in its uses: Salt is a conservation agent after all, and salt-cured meats don't spoil. Salt as a purifier appears in Shinto (Where it is used as a ritual purifier and small mounds of salt can be used to repel evil spirits) and Christianity (where it is used before mass and to consecrate a church).

* Myth/NorseMythology: When Baldr/Balder/Baldur, the son of Odin, was born, his mother Frigg made all living things vow not to be able to hurt him. The only living thing that didn't make this promise was mistletoe, as she felt it was too young to be bound to such a promise, and so it alone would be fatal to him. The gods made a game of it, throwing random items at Baldr and amusing themselves by watching the projectiles deliberately avoid striking him. Loki, the trickster god, deceived her so that she would reveal this weakness. He acquired some mistletoe and brought it to the blind god Hodr/Hoder/Hodur, telling him that he should also get to participate in the gods' fun little game; of course, when the mistletoe struck Baldur, it killed him. Baldur's death was the start of the chain of events that led to Ragnarok,

[[folder:Anime & Manga]]
* ''Anime/EighthMan'': Tobor the 8th Man recharges his powers with an inhalant stored in small, thin, white tubes that he carries in a cigarette case. When the bad guys allow him OneLastSmoke before executing him, this is great; when he has a fight where kids can see him, he worries about setting a bad example by appearing to smoke.
* ''Manga/AhMyGoddess'':
** Urd is put to sleep by Enka music, traditional Japanese ballads (in the Viz translation, it becomes polka music). When someone tries to take advantage of this fact, [[MundaneSolution she just pops in earplugs]].
** Mara is weak to rock music; it causes her to dance uncontrollably.
* Shiina from ''Anime/AngelBeats'' is Manga/{{Ranma|OneHalf}} turned [[ExaggeratedTrope Up to Eleven]]: a ridiculously hypercompetent ninja, but when she sees a puppy about to go over a waterfall she instinctively does a StupidSacrifice, getting them both killed...and it was a ''stuffed'' puppy. The puppy trap was actually meant for Angel, so it's possible she has the same weakness.
* In ''Manga/{{Bleach}}'', the Noveno Espada Aaroniero Arruruerie can't use his shapeshifting when in sunlight. Though he can still use any of his other 30,000+ powers (not that he does before getting killed, but he had the option). To make matters worse, he lives in Hueco Mundo, which has no natural sun. His boss builds a fake one for no discernible reason.
* In the ''Anime/CowboyBebop'' episode "[[Recap/CowboyBebopSession20PierrotLeFou Pierrot le Fou]]", Tongpu is a psychotic, unstoppable, bulletproof PsychopathicManchild. He has exactly two weaknesses, both psychological: [[WhyDidItHaveToBeSnakes a pathological fear of cats]] due to the experiments that he was subjected to, and [[spoiler:[[MinorInjuryOverreaction feeling pain]], induced in this case by Spike hurling a knife (a projectile too slow to be stopped by Pierrot's experimental shield) into his thigh]].
* From ''Manga/CromartieHighSchool'':
--> My name is Yutaka Takenouchi, and I have only one weakness ... I am ''very'' susceptible to motion sickness!
* ''Manga/{{Dandadan}}'': The mantis shrimp Gig Worker has the punching ability of a mantis shrimp, and is ''even more powerful'' underwater, but ''doesn't have gills'', so it keeps having to surface to breathe.
* ''Manga/DontMeddleWithMyDaughter'': As a goddess, Athena possesses Herculean [[FlyingBrick strength and nigh-invulnerability]]. So her enemies learned to use her feminine modesty [[DefeatByModesty against her]], by sexually molesting her in public.
* ''Manga/DragonBall'':
** The only way to defeat Chiaotzu's psychic attacks is to break his concentration. Krillin does this quite comically by asking him ''extremely basic math questions.'' Like 9 - 1. After that, his teacher the Crane Hermit immediately [[MundaneSolution gave him remedial math lessons]].
** The sound of whistling can seriously incapacitate Namekians, as a result of their incredibly acute senses of hearing. This becomes a plot point in ''Anime/DragonBallZLordSlug'' where Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
** In the Otherworld Tournament filler, Goku shows that he's exceptionally vulnerable to being tickled given that Caterpy is able to hold Goku in place and [[TickleTorture torture]] him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted.
* ''Anime/DragonBallSuper'':
** A God of Destruction is an extremely powerful being holding its real power back. However, it turns out their existence is tied to the leading Supreme Kai of their universe. If a Supreme Kai were to be killed, the God of Destruction goes away as well. Most of the shown Supreme Kais are unfit for combat and would be easy to dispatch.
** Auta Magetta is a more direct example in that he is almost completely invulnerable and, when motivated enough, near unstoppable, even with Goku, Vegeta, and the like at the levels of power they're at. He has never been shown to have sustained physical damage of any kind. The only way he's ever been stopped is through exploitation of his low self-esteem and sensitive nature: If he hears anyone insulting him, no matter how mild, he becomes distracted and, eventually, unable to attack or even ''move'' as he's paralyzed in sadness. His friend Botamo eventually devises a MundaneSolution to this via plugging his ears while riding on Magetta's shoulders, which apparently is enough to give Super Saiyan Blue Vegeta major problems.
* ''Literature/{{Durarara}}'':
** Celty is an immortal dullahan, but has a couple of absurd weaknesses:
*** She is ''terrified'' of aliens. In a special side story, she tries to play a video game with 'Blue Kappas' as the monsters with the logic that since they're not aliens, she'll be fine. Unfortunately, the monsters are indeed aliens and she's found an hour later, hiding in a closet.
*** [[spoiler:If someone can get her angry enough, such as in the case of Kasane possessing Shinra, Celty will almost instantly turn into an amorphous, insentient monster.]]
** Saika can also be undermined if someone has a strong enough pain tolerance, and thus she will be unable to possess them.
** Despite guns, knives and trucks being ineffective against Shizuo, as it turns out, pens work. Somehow. He also is just as vulnerable to suffocation as anyone else.
** Downplayed in Ruri's case since, as a dhampir, she only gets sunburns very easily and does not like garlic.
* ''Manga/FairyTail'':
** Natsu is MadeOfIron, he can breathe fire and cause [[PersonOfMassDestruction massive property damage simply by punching someone]], but he too suffers from the ignominious susceptibility to ''transportation''. At least once it was actually exploited to defeat him in battle. This motion sickness seems to extend to being carried by people, as well. He's perfectly fine being taken to flight by Happy the cat, however, reasoning that Happy isn't a vehicle. According to Rogue, ''all'' Dragon Slayers suffer from this.
** Wendy however, doesn't suffer from transportation. Rather, She's weak to pickled plums. [[spoiler: After the 1-year timeskip, she started to suffer from transportation.]]
** Gajeel, similarly only began suffering from motion sickness after joining Fairy Tail. It's never explained why it never bothered him before, only that eventually all Dragon Slayers gain this weakness. Even the artificially-created ones like Laxus and Cobra suffer from it.
** [[spoiler:The first Dragon Slayer Irene Belserion]] eventually explains that this is because becoming a Dragon Slayer involves being infused with Dragon magic, which effectively makes them part Dragon. As a Dragon Slayer's power increases, they become more Dragon-like [[spoiler:to the point of ''becoming'' Dragons if the process isn't halted somehow]]. The BizarreAlienSenses of Dragons don't mix well with human bodies, [[spoiler:and even Acnologia, the [[NighInvulnerability nigh-invulnerable]] [[TheJuggernaut unstoppable]] Dragon King is just as vulnerable, nearly throwing up from literally ''holding onto the side of a speeding airship'']].
* In ''Manga/FukashigiPhilia'', the villain Shidow is extremely fearful towards water to the point if he gets in contact with it, he will go berserk and have his abilities neutralized.
** All of the Abilities Users created by [[spoiler:Noa and Isumi]] have a particular weakness - it's usually whatever originally killed them (such as water for Shidow, who drowned, or dry ice for another, who froze to death).
* ''Manga/FullmetalAlchemist'':
** In the manga and second anime, Pride can project razor-sharp tentacle-like [[LivingShadow shadows]] from his body. But he can only project them where ordinary shadows could be cast; complete darkness renders him unable to attack and bright lights can cut off his tentacles. Granted, he is still near immortal even when he can't attack; in a way he is both the most powerful and the most vulnerable homunculus.
** A common mistake for people in the series is to assume that Flame Alchemist Roy Mustang is useless when wet (or without his gloves). This is only true to a certain extent - while his gloves can't create a spark when they're wet, there's nothing stopping him from using something else in their place (like a lighter) as long as he has access to the right kind of transmutation circle. He's arguably ''more'' dangerous with lots of water around so long as he has an alternative method of creating a spark, as he can split the water into hydrogen and oxygen and then ignite it... the problem is that unless he can trap the target in an enclosed area with the water he's liable to blow up any nearby allies and ''himself'' at the same time, hence this technique being very rarely used. The joking doesn't change the fact that he definitely [[ColonelBadass earned his rank]].
** A combination of this and BerserkButton: Insulting [[PintSizedPowerhouse Ed's]] height, while entertaining, has a tendency to impair his judgement as he blindly charges the enemy. This is mostly PlayedForLaughs, although [[CreepyChild Pride]] uses it once to get an edge in combat.
---> '''Pride''': Appearances can often be deceiving. Isn't that right, little alchemist?\\
'''Ed''': Grk!\\
''(Pride attacks)''
** PlayedForLaughs in one of the manga's early omake, where Hawkeye defeats both Ed and Al with ''[[ItMakesSenseInContext a magnet]]''.
* Shiina in ''Manga/GourmetGirlGraffiti'' '''absolutely''' can't be splashed by rain; any amount would make her [[InstantIllness instantly sick]] for a whole week. This is why she was wearing a whole hazmat gear when she's "risking it" to the cram school in chapter 6/episode 4. Dishwater apparently does the same thing, as seen in episode 7.
* Italy from ''Webcomic/HetaliaAxisPowers'' can run insanely fast, and [[spoiler: defeated the Ottoman Empire, which was pretty powerful at the time, while he was only a child]]. According to the author, the only thing keeping him from dominating Europe is that he's just too afraid to.
* [[OurFairiesAreDifferent Fairies]] from ''Literature/HumanityHasDeclined'' are killed by EM waves, a.k.a. light, the most ubiquitous thing in the universe. If the setting wasn't AfterTheEnd, they'd be screwed, and they still have problems with it anyway.
* ''Manga/JoJosBizarreAdventure'':
** Vampires are seen as nearly invincible gods among men...unless the sun is out. Or you punch them with sunlight-infused martial arts. Or you hit them ''really'' hard in the brain and screw up their ability to control their own bodily functions (though not many beings out there ''aren't'' weak to the ChunkySalsaRule). Or just have a Pillar Man (essentially super vampires) so much as touch them, which will cause them to be instantly absorbed.
** Pillar Men also have a weakness to the sun and Hamon, but due to their biology (and possibly Kars' stone masks) they [[TakenForGranite can turn themselves into something similar to stone]] blocking off UV rays. When Kars becomes the UltimateLifeform, [[OneHeroHoldTheWeaksauce he loses his weakness to the sun]] among other benefits.
** Rock Humans in part 8 are resistant to damage and fatigue, but despite being partly rock they're dependent on oxygen, "breathing" it through their skin. This means that submerging them in water causes them to rapidly "suffocate" and break apart, though Josuke probably didn't help matters when he stole the oxygen from one's body in an attempt to force him to surface.
** Some powerful Stands also incorporate this trope for narrative balance reasons. One key example is [[Manga/JoJosBizarreAdventureDiamondIsUnbreakable Part 4]]'s Red Hot Chili Pepper. Since it becomes stronger and faster the more electricity it has access to, with no stated or hinted upper limit, it can be said to be one of the most powerful stands in Part 4. But this comes with two weaksauce weaknesses; first, if you cut off its access to electricity, say, by destroying the motorcycle battery it was hiding in, it rapidly weakens and fades. Second, since salt water is such an excellent conductor, immersing it in the ocean will cause it to rapidly dissolve.
** For certain stands, ''the user'' is their weaksauce weakness. All non-automatic stands [[{{Synchronization}} share damage]] with their users, but some stands are pretty much impossible to directly hurt, like Yellow Temperance (amorphous blob), The Sun (too hot for anyone to get near it), The Fool, and Horus (can reform from sand and ice, respectively). Their ''users'', on the other hand, can be hurt like normal (and are often [[GlassCannon glass cannons]]), and their defeats will cause their stand to de-manifest.
** There's also The Hand in part 4, a Stand with the ability to ''literally erase anything, even space itself, from existence.'' A truly overpowered stand, in principle...except its user is Okuyasu: a [[JapaneseDelinquents Japanese Delinquent]] with the IQ of [[DumbMuscle a brick wall]] who doesn't have the brains to use it creatively nor the heart to actually use it directly against people.
** ''Manga/JojosBizarreAdventureStoneOcean'' has Ungalo's Stand, Bohemian Rhapsody, which has the incredible power to ''cause every single fictional character ever written to come to life''. On top of that, anyone who identifies with that character will [[YouCantFightFate be doomed to replace them and suffer the character's fate]]. This causes massive devastation across the entire world (for example, characters from ''Manga/FistOfTheNorthStar'' destroy Tokyo while reenacting their battle)... until Weather Report easily stops it dead in its tracks by creating an original character named Put-Back, who returns all of the summoned characters to their stories. As a side-effect, this also permanently renders Bohemian Rhapsody completely unusable, since any future attempts at reactivating its ability would also summon Put-Back, immediately cancelling it. Ungalo [[DespairEventHorizon instantly loses all will to live and falls into a coma]] upon realizing this.
* From ''Manga/KenichiTheMightiestDisciple'', we have Akisame Koetsuji, the Jujutsu Philosopher. Master martial artist, a doctor so skilled he can raise the recently dead, and [[TheAce master of a bazillion and six other fields]]. He's one of Kenichi's six super-powerful masters... and green peppers make him so ill that he can be held at bay simply by hanging one outside his door.
* ''Manga/{{Kinnikuman}}'' is weakened by milk. Though after he goes insane during his match against Curry Cook and ''drinks'' the stuff, it becomes apparent that he just thinks it's disgusting.
* Emperor Nightmare, the leader of Nightmare Enterprises (Holy Nightmare Co. in the Japanese version) in ''Anime/KirbyRightBackAtYa'', is weak against AND afraid of [[spoiler:one weapon that Kirby can take control of by swallowing his Warp Star: the Star Rod]].
-->'''Nightmare''': Aaaah! How did Kirby discover the secret?! That pitiful little Star Warrior has found my only weakness! [[spoiler:I am helpless against the power of the Star Rod! [[DeathCryEcho WAAAAUUUUGGGGHHH!!!!]]]]
* ''Anime/{{Macross}}'':
** ''Anime/SuperDimensionFortressMacross'' has an alien attack force made up of gigantic ScaryDogmaticAliens who are a {{Proud Warrior Race|Guy}} do a mass MookFaceTurn because of... singing. And souvenirs. In fairness, it does make sense in the story (at least as much as ''Literature/TheWarOfTheWorlds'' Martians being vulnerable to Earth's diseases) and is perhaps one of the best logical conclusions to a typical alien's PlanetOfHats treatment. The Zentradi have no culture to speak of other than fighting, so when exposed to humans and their culture in the form of songs and interacting with the other gender after sending a team of spies to the SDF-1, typical Zentradi start feeling emotions, questioning their purpose, and [[HumanityIsInfectious becoming similar to humans]]. Because of this, their entire fleet gets deemed "contaminated" by the unexposed Zentradi and programmed for destruction. In the face of this EnemyCivilWar, they wisely choose to ally with the humans. Still, it doesn't quite wash away the faint air of ridiculousness when Minmay's singing becomes an ''offensive weapon'' to unbalance the unexposed Zentradi in their attack.
*** Those who consider Minmei TheScrappy half-jokingly argue the Zentraedi were distracted by her singing because [[DreadfulMusician it was so bad]] in the ''Anime/{{Robotech}}'' dub.
*** The initial use of Minmay's voice as a weapon is actually short-lived: while the Zentradi were initially too distracted to react, as soon as the heroes opened fire they started firing back. The real decisive weapon in that engagement was Minmei kissing Kaifun: the Zentradi were so disgusted they stopped fighting effectively, trying absolutely anything to erase the image from their minds, including firing in the middle of nowhere (a Zentradi heavy cruiser was observed doing exactly this as Hikaru locked his nukes on it) and listening to Minmei's songs.
** Taken to even greater extremes in ''Anime/{{Macross 7}}'' where the spirit draining Protodevilns's only weakness is actually the ''energy'' produced by music. It produces a spiritual energy "too pure for them to absorb" and regenerates the lost energy in those drained by them.
*** In one humorous scene, a Protodeviln gets a "brilliant idea" for shielding himself against the humans' singing. [[MundaneSolution He puts on earplugs.]] This actually does work, but Basara just plays even louder. Afterward the Protodeviln installed a noise canceller in his mech, which proved much more effective.
*** Incidentally, one OVA shows us that Minmei's registered songs have absolutely no effect on unexposed Meltrandi (the FEMALE Zentradi), who just ignore them (partly because they had the common sense to just jam the frequencies used to broadcast them), but BASARA's songs made them groupies the very moment he managed to get them to hear him. It baffled a [[GeneralRipper UN Spacy higher-up]], who had assumed the Meltrandi would just jam the broadcast (both times the Minmei tactic had been seen used had been with broadcasts the enemy didn't jam for one reason or another).
* In ''Manga/MissKobayashisDragonMaid'' Tooru mentioned that her friend Herensuge was beaten to death by an egg without a yolk. [[ShownTheirWork This is actually a reference to the legend that Herensuge could be killed by cracking an egg on its head]].
* In ''Manga/{{Moriking}}'', the ridiculously powerful king candidates are all susceptible to cardiac arrest via consuming overly spicy food like kimchi stew or curry. Moriking and Oki find this out the hard way, but it's PlayedForLaughs and they're perfectly fine afterward.
* ''Manga/MyMonsterSecret'': Akane is an ancient demon whose powers include mind control, teleportation, shapeshifting, duplicating herself, and summoning meteors. She also has a ''massive'' SweetTooth, and anyone can foil her plans by holding up a piece of candy, which she will immediately fixate on.
* In one episode of ''Literature/MyriadColorsPhantomWorld'', the team are pitted against a [[{{Youkai}} Youkai Phantom]] in the form of a sunflower. They can't beat him until Koito works out that [[LogicalWeakness because he's a sunflower, he can only face towards the sun]]. They therefore defeat him by simply walking round him and attacking from behind, where he can't see or reach them.
* In ''Anime/TheMysteriousCitiesOfGold'', rainbow light causes the Golden Condor to malfunction and crash down on the ground.
* In ''Manga/{{Naruto}}'' Konan of the Akatsuki is, like all members of that group, very powerful. Yet her [[PaperMaster paper-based techniques]] can be completely nullified by spraying oil on her to make her stick together (a technique one human ninja and some summoned toads have), although water can release her.
** Madara once said that he's sensitive to people standing behind him, and that he couldn't so much as pee if there's someone immediately behind him. He was telling the truth.
* Adam Blade from ''Manga/{{Needless}}'' has a weakness for little girls, and usually ended up getting his butt kicked because of this. Though later in the manga his weakness had developed from mere lolis to naked lolis. On the other hand, his love for lolis can temporally boost his strength and saves him from a LotusEaterMachine, so it's subverted.
* ''Manga/OnePiece'':
** Anyone who's eaten a Devil Fruit gets amazing powers, but they all share one weakness: the inability to swim. ''At all.'' If they are so much as half-submerged in water of any kind, they become paralyzed (and for many, their powers stop working). Which is ''kind of a problem'', seeing as how many of the encountered Devil Fruit users are '''pirates or marines''' in a world that's '''''[[OceanPunk ninety percent ocean]]'''''. If a Devil Fruit user touches Seastone - a material that has been described as "solid sea" - they'll feel the same effects as if they were fully submerged in water.
** Though this is more of a subversion in that this weakness very, very rarely becomes an issue, especially considering how many Devil Fruit users are in the series and how four of them are in the main cast. This is even lampshaded in the Enies Lobby arc; when two members of [[QuirkyMinibossSquad CP9]] are trying to decide whether or not to eat Devil Fruits that had been provided to them, [[DragonInChief Rob Lucci]] mentions that being unable to swim isn't much of a problem (then again, all members of [=CP9=] have the ability to DoubleJump, so there's that).
** Depending on the situation, basic hypnosis (such as Jango's ring or Ms. Goldenweek's emotion-altering paint) serves as one of the weaknesses for Monkey D. Luffy, the protagonist. Due to his simple-minded nature, he just won't have the sense to turn away, which makes him helpless and left to the devices of his enemies.
** Water is actually a much greater weakness to [[DishingOutDirt Sir Crocodile]], as he is a man who can turn into sand, making him [[NighInvulnerability Nigh-Invulnerable]] to most attacks. But if water strikes him, the sand "sticks together," and he is rendered unable to turn into sand at all, thus leaving him fully open to attack. He has a natural defense in that his sand powers extend to causing alarmingly fast dehydration with direct skin contact. In addition, he has the good sense to not only do his villainous business on a relatively large island, but on a ''desert island.'' He also uses Dance Powder to not only to frame the king in an effort to overthrow him, but also to stop it from raining in the town he was using as a base. In addition, on the off-chance that someone was able to negate his Logia defense for a significant period of time (like with Luffy), he's a master tactician who's skilled in other combat arts as well. His hook has a second, ''poisoned'' hook under it, and if ''that'' hook gets broken, [[CrazyPrepared he can eject a knife in its place]].
** Fishmen or Fishmen-hybrids who have eaten Devil Fruits are unable to swim like any other Devil Fruit user, but unlike them, they still can breathe underwater. The problem with that is that they can't move underwater without being surrounded by a special coat of bubble.
** In-universe, at least, we have Enel. His ShockAndAwe abilities are considered among the most godlike Devil Fruit powers in the setting, yet Luffy's relatively low-tier RubberMan powers completely and utterly negated them, to the point that Enel had to get really creative with his powers just to find a way to harm Luffy at all, and only his unrelated CombatClairvoyance protected him from getting beaten to a pulp pretty much instantly.
*** Logia-type Devil Fruits in general tend to react weirdly to various elements, and almost always have at least one weakness that completely shuts down their powers. Moreover, hitting their elemental forms with [[KiManipulation Haki-infused attacks]] damages them as if they were in regular form.
** Blackbeard has one of the most powerful abilities in universe. With his Darkness manipulation, he can wipe out entire towns in seconds, shoot the debris out like a cannon, and negate other Devil Fruit powers through physical contact. But he has a major weakness that isn't shared by any other fruit of the same class as his. Most Logia-users are Nigh-Invulnerable due to being able to dematerialize around attacks, but because Blackbeard's ability makes him a "Gravity Man", his body is always in physical form. Not only that, but the same qualities that let him negate other Devil Fruit powers (by forcibly holding their bodies together) also draws attacks INTO him. In short, attacks are both more likely to hit him ''and'' always exceptionally damaging.
* ''Manga/PokemonAdventures'': Roxanne's Nosepass is very powerful, but as it is basically a living compass, it can only face north. Once an opponent can get behind it, it cannot defend itself.
* ''Manga/RanmaOneHalf'':
** Ranma Saotome can be incapacitated by [[WhyDidItHaveToBeSnakes the mere sight of a cute little kitten]]. However, those who attempt this should note to apply said weakness quickly and forcefully -- prolonged, intense exposure has a tendency to [[UnstoppableRage backfire]]. Thanks to his GenderBender curse, [[KillItWithWater cold water]] can also count as a weakness. Technically. Ranma's female form has less strength and reach than his male form (though the anime is explicit that Ranma's speed is boosted in this form, so it's more of a trade), but s/he can still pull off all of his/her normal attacks. Based on a character with an identical curse, it's also possible that being in female form weakens his [[KiManipulation Ki Attacks]].
** [[CuteBruiser Shampoo]] and Ryoga Hibiki have an even worse case of the water weakness than Ranma does; Jusenkyo made them become a [[ForcedTransformation little kitten and miniature pig]] respectively when splashed with cold water. So they go from incredibly powerful fighters to harmless little animals whose only recourse is to run or hide until they can get some hot water. Genma Saotome, Ranma's father, subverts it; his panda form loses little, if any, speed and agility while gaining in strength and toughness due to the increased [[StoutStrength bulk]]. Mousse, meanwhile, seesaws between subverting this trope and playing it straight with his duck curse; while it is much smaller, weaker and can't use his physical attacks, it can fly and he's still capable of throwing barrages of knives, darts and bombs in it.
** And a non-water version applies to [[OldMaster Happosai]], who is such a DirtyOldMan that his perversion becomes his own Achilles heel. If there is a fight serious enough, or a reward great enough, that he can't be immediately distracted from whatever he was doing by the sight of girls in skimpy clothing, bare cleavage or a bra, it hasn't come up in the series. He can even be lured right into dangers simply by tossing a bra in the right place.
** Spoiled prince Saffron has incredible fire magic powers, the ability to fly and regenerate so fast that he can tear off his own wings to use as throwing weapons and grow them back in seconds, but because of his lax and pampered upbringing he can't take any sort of physical blow and in a world full of martial artists that's a big problem.
* The specialists, the Paper Sisters in ''Anime/{{Read or D|ie}}ream'' can telekinetically manipulate paper... unless it's ''wet''. This was not a weakness for Yomiko Readman, who ''is'' shown on camera manipulating paper while underwater. This is actually [[JustifiedTrope explained in-universe]]. The Paper Sisters' powers are essentially imperfect clones of Yomiko's, artificially created by Dokusensha; which is why they are weaker and more specialized/limited. Water naturally disrupts the structural integrity of paper, and their inferior powers are not sufficient to maintain it the way Yomiko can.
** One minor villain in ''Anime/RODTheTV'' is an expert on sound, to the point of knowing a certain frequency that can [[PowerNullifier nullify]] the protagonists' PaperMaster abilities, rendering them powerless against him. Anita's solution is to just [[ThrowTheBookAtThem throw a book at him]]; A normal, unpowered hardcover book, which flies right past his defenses and hits him right in the face, knocking him out.
* In ''Manga/RosarioPlusVampire'', vampires are considered the high end of the monster scale, but the fact that you can take a vampire down with a glass of water kinda puts a [[{{Pun}} dampener]] on that idea. Though, you'd have to be of werewolf speed to even ''consider'' hitting them with the stuff in the first place. Vampires are ironically said to have the most weaknesses compared to any other monster. Things like silver would also do them in. However, they are still incredibly strong even when weakened by those weaknesses, albeit far weaker.
* The titular servamps of ''Manga/{{Servamp}}'' are made of this. They cannot swim in running water, cannot separate from their eve or both will eventually die, cannot touch holy water without collapsing, will be weakened to the point of personality changes if their contract item breaks and turn into an animal immediately when exposed to sunlight.
** Tsurugi is a magician and has the same weaknesses as a normal human would (e.i. blood loss, starvation, etc) though he is more resilient. However, as he never learned how to swim and according to himself '[he] sinks like a rock', Tsurugi is so vulnerable to drowning he can't even fill up his bathtub too much.
* In ''Literature/{{Slayers}}'', female spell-casters have a very common and mundane weakness: menstruation. During a woman's menstruation period, her magical power output drops tremendously, so much so that even the protagonist, Lina Inverse, who is one of the strongest sorceresses in the entire Slayers setting, is barely able to cast a novice ''Light'' spell during her period. This is apparently a well-known weakness, as Zelgadis and even [[IdiotHero Gourry]] both figure out why her powers are weakened at one point, though Gourry is so ignorant that he doesn't understand the significance of "that time of the month" and just assumes it's magic-related.
* The Dai Gurren in ''Anime/TengenToppaGurrenLagann'' is a walking battleship... that is not designed to go on water. A ''battleship'' that ''isn't designed to go on water''.
* ''Manga/UshioAndTora'': Youkai in general are implied to have all one or two weakness, aside from the common one to ColdIron and spiritual powers:
** The Stone Eater (a giant two-headed centipede monster) can be easily killed with a weapon moist in human spittle, a nod to the legend of Hidesato Tawaratota.
** Fusuma can only be hurt by fire and black laquered teeth. Since he also lives in the sky, Tora lampshades how difficult it is to actually take advantage of said weaknesses.
** The Vampire is afraid of fire, but also recoils from both Daoist talismans and Christian holy icons, being unable to use any of his powers in front of a crucifix.
** The jashin Hitotsuki, according to the manual, can't stand tobacco smoke.
** The Yamauo normally dwells deep below the surface, but exposure to sunlight makes him explode into smithereens.
* ''Anime/YuGiOhArcV'': Gongenzaka's Superheavy Samurai Deck functions without having Spell/Trap Cards in his Graveyards, so he cannot pick up Action Cards without handicapping him. This is normally not a problem, as his deck is pretty strong, but it makes him unsuitable in Tag Duels, where both partners share the same field and Graveyard, thus his deck is very likely to get screwed by his partner or his partner is screwed for not using Spell/Trap Cards when they actually need them. [[spoiler:Gongenzaka later gains a new ace monster that can banish Spell/Trap Cards from his Graveyard, yet it is still not suitable in Tag Duels.]]
[[/folder]]

[[folder:Film -- Animation]]
* ''WesternAnimation/TheMitchellsVsTheMachines'': The PAL Robots' main weakness is that they are unable to tell if Monchi is a dog, a pig, or a loaf of bread, and they'll [[LogicBomb short-circuit while trying to figure it out]].
* The Blue Meanies from ''WesternAnimation/YellowSubmarine'' are repelled by positivity in any form. This doesn't work out so badly, though, since their entire arsenal is built around the proliferation of depression and despair, but it does still leave them vulnerable to [[ThePowerOfRock music]].
* This trope appears as a pastiche in ''WesternAnimation/{{Bolt}}''. The titular dog believes he has superpowers because he never leaves the set of a TV show. When he is accidentally shipped across the country his powers "mysteriously" vanish, and he blames the Styrofoam packing peanuts he was shipped with.
* Invoked by Syndrome in ''WesternAnimation/TheIncredibles1'' with the Omnidroid. It was built for an EngineeredHeroics scheme, so he designed it to be [[NighInvulnerability nigh-invulnerable]] and unstoppable... to anything ''except'' the remote control that Syndrome wore on his wrist. [[spoiler: It doesn't end well for him when the Omnidroid's adaptive A.I. [[GoneHorriblyRight adapts to cover for that weakness]], but it does eventually allow the heroes to win, after a period of desperately playing keep-away while the Omnidroid attempted to destroy the remote.]]
* ''WesternAnimation/{{Megamind}}'' has Metro Man having a weakness to copper, which causes Megamind to kill him without even meaning to. ([[spoiler:[[SubvertedTrope Except that he actually made it up]] in order to [[FakingTheDead fake his death]] and retire]].) This is even lampshaded by Megamind:
-->'''Megamind:''' Your weakness is ''copper''!? You're kidding, right?
* Stitch of ''WesternAnimation/LiloAndStitch'' is speedy, clever, and able to lift 3000 times his own size, but still has comedic weaknesses:
** He is too heavy to swim. One reason falling in water is so damaging is that Stitch tends to ''panic'' when he's underwater. He eventually starts to handle deep water better; one episode of ''WesternAnimation/LiloAndStitchTheSeries'' (the theme of which was conquering your fears) had him fall into a swimming pool, but he manages to keep calm, hold his breath, and climb out without issue.
** He might be able to lift 3000 times his own size, but not an ounce more. Gantu was able to have a pile of stuff crush Stitch by placing a feather on it.
* ''WesternAnimation/TheKingAndI'' has this in the form of every single solitary minion the BigBad conjures up. His first pair of minions are giant traditional Chinese dragons who ruthlessly attack the teacher's ship to the point that it's near sinking. How are they defeated? Whistling. Everyone aboard whistles a happy tune and they dissolve into nothingness.
* In ''WesternAnimation/ThePrincessAndTheGoblin'', the goblins have two weaknesses: really squishy feet (the Queen wears stone shoes) and ''singing''. They freak out when they hear people sing. At least it's a nice song.
* In the 1973 Russian version of ''Animation/TheNutcracker'', the evil mice [[SneezeOfDoom explode if they sneeze]], so any sneeze-inducing substance is deadly to them. In the Nutcracker Prince's backstory, his father the King defeats the Mouse Queen by dousing her with [[PepperSneeze pepper.]]

[[folder:Film -- Live-Action]]
* ''Film/TheWizardOfOz'' gives the trope-codifying example: the Wicked Witch of the West [[KillItWithWater melted when Dorothy splashed her with a bucket of water]].
* ''Film/ReturnToOz'' continues the proud tradition of Oz villains having an unexpected, thorough weakness that kills them on the spot. In this case, the Nome King (and seemingly Nomes in general) [[spoiler:find regular chicken eggs to be extremely poisonous. All of them react to Dorothy bringing a chicken along like she had an armed bomb with her, and when the King accidentally ingests one of its eggs he dies (and falls apart) within the minute]].
* ''Franchise/ANightmareOnElmStreet'': Freddy Krueger, the nigh-unstoppable humanoid monster that can kill you in your dreams, has a weakness to ''[[ClapYourHandsIfYouBelieve people not believing in him]]''. This becomes far funnier when you realise that his weakness is the same as ''[[Literature/PeterPan Tinkerbell]]''!
* In the AffectionateParody superhero movie ''Surge of Power: The Stuff of Heroes'', both the hero and villain have their powers nullified by the presence of peppy music. Fortunately the hero is able to save the day with his incredible accuracy with slingshots.
* The aliens in ''Film/{{Signs}}''. It's [[NightmareRetardant hard to feel threatened]] (retrospectively) by creatures which will dissolve in an April shower or corrode in a particularly humid breeze. And are completely incapable of breaking down wooden doors.
* In Shyamalan's earlier film, ''Film/{{Unbreakable}}'', water is also used as a [[KryptoniteFactor weakness for the main superhero character]]. In that case, though, it isn't that he is especially vulnerable to water, but rather he is just as susceptible to drowning as a normal person. If he drinks something too quickly, he will choke and if he is submerged he will succumb to drowning just like everyone else -- though it was theorized that the dense bone and muscle that make him ''unbreakable'' also make him ''unfloatable'' (or the character simply can't swim). There is a complicating factor in the scene where he ends up almost drowning in a swimming pool: he's tangled up in a big piece of fabric, which would give anyone a bad time while in water. It is also a [[WhyDidItHaveToBeSnakes psychological weakness]]: he had almost drowned once as a child (probably due to the aforementioned bone density), an event so traumatic he blocked it from his memory. That would make anyone nervous around water, even if they couldn't remember why.
* ''Film/InvasionOfTheSaucerMen'': The aliens are melted by ''light''. There is nothing lamer. Especially considering they were done in by [[spoiler: the headlights of teenage hot rodders]]!
* The Bioraptors (also called "Demons") of ''Film/PitchBlack'' has a similar weakness to light. Though this actually works, as most of the movie is during a solar eclipse and they broke their flashlights. Oddly enough, the creatures are shown moving about in the light, albeit cautiously, before the eclipse. Compare this to later on, when a lighter is enough to make them run away...
* The weakness to light appeared in ''Film/AttackOfTheEyeCreatures'' (because it was an almost word-for-word remake of ''Invasion of the Saucer Men'').
* Also happens in ''Film/TheMolePeople'', in which a lost colony of ancient Sumerians living BeneathTheEarth had adapted to their lightless conditions to the point where our heroes can kill them with a ''flashlight''.
* In ''Film/TheDayOfTheTriffids'', the title monsters are melted by sea water. Nearly as lame. In [[Literature/TheDayOfTheTriffids the original novel]], ironically, [[KillItWithFire flame-throwers]] are among the most effective anti-Triffid weapons.
* The Tenctonese in ''Film/AlienNation'' (the movie as well as [[Series/AlienNation the series]]) are harmed by ''salt water''. Seawater is like acid to them. They live mostly on the Californian coast; while they do develop a tolerance to it, direct exposure is still harmful to them. There is a slightly funny moment when the police find the partially-dissolved body of a Newcomer washed up on the beach. When asked how they were able to identify him, they simply shrug and show his soaked wallet. All his clothes were, naturally, fine too.
* In the Creator/DisneyChannel movie ''Film/UpUpAndAway'', the weakness of the superhero family is aluminum foil. However, it's never made clear if it was just their family or all supers who are vulnerable to foil. Both [[Characters/SpiderManPeterParker Spider-Man]] and Characters/{{Superman|TheCharacter}} are mentioned to exist in this 'verse, and they don't have any weakness to aluminum foil (although Supes has his own weakness). The bad guys definitely assume that all supers have this weakness, as, when Randy claims to have powers, they give him some foil to test it.
* In ''Film/{{SYNGENOR}}'', the title creatures were created to be the perfect soldiers for a war with the Middle East. They don't need to eat or sleep, are immune to most weaponry, and reproduce every twenty-four hours. Their only weakness? Water is like acid to them. It's somewhat hard to be afraid of a super soldier that can be defeated with a super soaker. Or, if worst came to worst, by peeing on them.
* In the Dead Gentlemen Productions (of ''The Gamers'' fame) running ''Demon Hunters'' series, Duamerthrax the Indestructible is a walking brick that is, well, all but indestructible. He's an "earthwalker", a demon said to have been kicked out of hell for being ''too mean''. Unlike other monsters and demons in the mythos, he's not susceptible to ordinary injury. He can eat the round of a large-caliber revolver jammed in his mouth ("Mmm! Nice 'n' leady!") casually regrows limbs after being dismembered, and generally shrugs off what few injuries he even takes while making terrible puns. So what's the convenient balance? We're told that every earthwalker has a weakness to some substance, "a plant, metal, anything". Duamerthrax's turns out to be ''mint''. Being shot repeatedly at close range with numerous handguns does little more than inconvenience him, but the breath of someone having just used breath spray causes him intense pain, water-guns full of mouthwash can inflict serious harm and [[spoiler:mint dental floss can do even worse things. Ultimately subverted; he turns out to have faked his defeat when the body count got where he needed it, regenerated almost immediately, and the credits show him happily dancing away. Then he gets hit by a car and sent back to hell in the beginning of the second movie]].
* ''Film/MarsAttacks''. The Martians' weakness is hearing high-pitched yodeling, such as in the song "Indian Love Call" by Slim Whitman, which [[YourHeadAsplode causes their heads to explode]].
* The Tomatoes in ''Film/AttackOfTheKillerTomatoes'' have the same weakness, in the form of a song called "Puberty Love".
* ''Film/TheMummy1999'': Imhotep in his incomplete form is immediately chased away when a cat is in his presence, because they guard the Underworld. Naturally, the heroes never do anything to exploit this weakness, such as by putting cats in the room full of the people he needs to kill to stop being vulnerable to cats.
* From 1966 superhero parody ''Film/RatPfinkABooBoo'': "Remember, Boo Boo, we have only one weakness... bullets."
* Like the Dalek example given below, in ''Film/RoboCop1987'', the killer robot ED-209 chasing the title character is taken out of play simply by trying to chase [=RoboCop=] down stairs that its chicken-walker legs are ill-suited to negotiate. Somewhat justified in that the ED-209 is just meant to look intimidating and get bought up by the military, not to do real police work.
* In an {{Homage}} to ''Film/TheWizardOfOz'', Death in ''Film/SixStringSamurai'' is killed when squirted with water.
* Derek Film/{{Zoolander}} can't turn left until his BigDamnHeroes moment. (Though continuity nitpicks will note that he does turn left (relative to himself, though not the camera) while in disguise while trying to retrieve Maury's computer.)
* The film adaptation of ''Literature/TheSpiderwickChronicles'' gives the villains several Weaksauce Weaknesses they didn't have in the original book series:
** Tomato sauce, vinegar and salt are effective at hurting goblins, with the former being outright corrosive to their bodies.
** Mulgarath's [[spoiler:bird form is ''just as fragile'' as a real bird, as Hogsqueal happily demonstrates by snatching and devouring him]].
* ''Film/MysteryMen'': [[{{Invisibility}} Invisible Boy's]] weakness is anybody looking at him while he is invisible. [[spoiler:(Machines, like motion detectors and cameras, don't trigger this.)]]
* The SuperCop in ''Film/SuperFuzz'' has super speed, super strength, invulnerability, telekinesis and so on, but he completely loses his powers when he sees the color red (probably a nod to Green Lantern and his vulnerability to yellow): a red traffic light, a red flower, a red ribbon, and he's harmless.
* The Psychlo homeworld of ''Film/BattlefieldEarth'' can be blown to (relatively) tiny bits with a nuclear explosion. You'd think that a nuclear bomb is substantial enough to bypass the Weaksauce bit, but remember that this is a ''[[ScifiWritersHaveNoSenseOfScale PLANET]]''. It'd be like a human exploding in a smear of gore after stubbing their toe. The given reason is that the planet's atmosphere ignites upon the slightest exposure to radiation. This, of course, implies that the planet completely lacks any heavy elements ''and'' has an insane set of Van Allen belts to protect it from any stellar radiation.
* ''Film/{{Sleepwalkers}}'' has monsters that are MadeOfIron, except when scratched by house cats.
* As is the usual with horror movie monsters, the 1973 {{Blaxploitation}} movie titular character Blackenstein was ImmuneToBullets, fists, and blunt objects -- traits which, when added to his SuperStrength, seemingly made him all but unstoppable. What is it that finally laid the mighty monster low? The primal forces of nature themselves or divine intervention? No. The police sicced the hounds on him. That's it. Doberman Pinscher fangs trump bullets, apparently.
* ''Film/MadMaxBeyondThunderdome'': Blaster is the immense Dragon to Master. According to people who want him dead and have been hunting for the right assassin to get the job done, "He can kill most men with his breath." His weakness: he can't stand high pitched noises. Max discovers this when the car alarm on his vehicle renders Blaster into a writhing, screaming, mess -- and promptly figures out that his [[ChekhovsGun whistle]] can have the same effect. [[spoiler:Not a surprise, given that this is a common problem for people with Down's Syndrome.]]
* The [[NinjaPirateZombieRobot undead mutant warrior things]] from TheEighties flick ''Film/NeonManiacs'' are virtually invulnerable except, like many other things on this list, they can be [[KillItWithWater dissolved with a squirt gun.]]
* The goblins from ''Film/Troll2'' are defeated when Joshua eats a double-decker bologna sandwich in front of them during the film's climax. They can't come within 20 feet of you after you eat 2 bites of bologna.
* In ''Film/ErnestScaredStupid'', what's scaring Ernest so much are a variety of trolls who, legend has it, are vulnerable to... milk.
* In ''Film/TheLairOfTheWhiteWorm'', a vampire's natural enemy is the mongoose due to vampires in this universe being snake-people. [[spoiler:The mongoose ends up getting killed anyway but it's still enough to make the BigBad retreat for a while.]] Also, playing the bagpipes puts them in a trance. [[spoiler: Unless they have earplugs.]]
* In ''Film/{{Hook}}'', the Lost Boys exploit Captain Hook's fear of the sound of ticking clocks, which they attribute to Hook's memories of being pursued by a clock-swallowing giant crocodile. Subverted when Peter points out that Hook can't really be afraid of the crocodile, [[spoiler: which he killed years ago; rather, Hook is afraid of ''time'', as he's become an old man beneath his wig and make-up, and old age is hardly a fear that can be dismissed as Weaksauce]].
* ''Film/SupermanIVTheQuestForPeace'' brings us the horror that is Nuclear Man who, for reasons unknown, is powered solely by the sun. The minute he is out of direct sunlight he stops dead. Even if he's in a well lit room but slightly in the shade, he's next to worthless. This is especially pathetic when you consider that, in canon, Superman's own powers are ultimately derived from sunlight, but ''he'' doesn't power down in the shade -- at least not unless he has to use his powers a lot before the next time he can catch some rays.
* In ''Film/TheTraveler'', the only way to counter Mr. Nobody is actually by [[spoiler:letting him [[IKnowYourTrueName hear his real full name]] ]], which will make him lose powers and become vulnerable to physical attacks. Kinda makes sense for him to conceal his identity throughout the film.
* Played for laughs in ''Film/{{Evolution}}'', where the aliens' critical weakness is to [[spoiler:selenium]], the best local source of which is in dandruff shampoo.
* Film/{{Hancock}}'s only weakness? His real wife. Any attempt to live a loving, fulfilling life with his wife of ''3,000'' years will cause them to both become mortal in order to die together. Unfortunately, Hancock has a hero complex to save people, which attracts bad guys who attack them in their weakened state. They argue, he leaves, they meet again and the whole cycle starts again. His wife says the gods who created them gave this as a gift. So that they could find love and be happy, and not have to see everyone they care about die as they remain [[WhoWantsToLiveForever unchanged and alive]].
* ''Film/{{ROTOR}}'' is about a robotic policeman gone mad. He's almost unstoppable except for being paralyzed by loud noises. This might not sound ''that'' dumb, until you witness him repeatedly frozen by people honking their car horns at him or playing a radio a little too loud.
* The SensoryOverload to the Kryptonians in ''Film/ManOfSteel''. Good thing Supes learned how to control it [[spoiler:and unfortunately, so did Zod]].
* Marcus Wright in ''Film/TerminatorSalvation'' is every bit as tough and unstoppable as you would expect [[spoiler:from a terminator...]] except for [[spoiler:his glaring exposed weakpoint in the form of his organic human heart (which isn't even covered with any sort of armor; it just hangs there in a big gaping hole in his chest, leaving it completely exposed to any stray pistol shot or well-aimed punch)]].
* ''Franchise/{{Godzilla}}'':
** In ''Film/Godzilla2014'', Godzilla's arms are very stubby compared to the rest of him. The male M.U.T.O took advantage of this a couple of times by jumping on his head and stabbing away at him with those long forelegs, with Godzilla having an extremely difficult time dislodging him since he could barely touch the top of his head. They are plenty strong, though, and he uses them to fight the female Muto.
** King Ghidorah in ''Film/GodzillaKingOfTheMonsters2019'' is a nigh-unstoppable living extinction event whose very wing-flaps create ''hurricanes''. His notable weakness? The same enormous wings that grant him superpowered flight also make him incredibly ungainly in water, rendering him almost entirely defenceless when Godzilla drags him into the ocean.
* The titular Film/NightmareMan is a pretty powerful fertility god, he can kill people, grab and crush people's hearts by sticking his hand in, control dead people as puppets, etc. His weakness, if the person he's possessed is on anti-psychotic pills he can't do anything at all.
* The aliens in the French comedy ''Film/LeGendarmeEtLesExtraTerrestres'' are physically tough, can teleport, and can appear as any person they desire. What's their weakness? Water (note: the film predates ''Film/{{Signs}}'' by a few decades). Apparently, they're MechanicalLifeforms (they're shown drinking motor oil at one point) and rust at the slightest touch of water in a matter of minutes. The worst part? They came in peace! It was the gendarmes' aggressiveness that made them hostile. In the end, the aliens are destroyed (with water, naturally), and [[BrokenAesop the gendarmes are hailed as heroes]].
* Even though Film/{{Thor}} is the God of Thunder and has the power of ShockAndAwe, he's still vulnerable to electric attacks from others, as we see in ''Film/ThorRagnarok''.
* In ''Film/TheThing1982'', the titular monster's assimilation powers only have one big flaw; it [[AssimilationBackfire acquires the weaknesses of its victims alongside their strengths]]. When it assimilates [[spoiler:Norris]], it unwittingly copies the heart condition he suffers from, which leads to it ''having a heart attack'' during a stressful moment. Things go FromBadToWorse when the rest of the team tries to resuscitate [[spoiler:"Norris"]] with a defibrillator, forcing the Thing to transform and blow its cover in order to stop the painful electric shocks.
* The playable characters in ''Film/JumanjiWelcomeToTheJungle'' all have lists of strengths and weaknesses. Some weaknesses, like Ruby’s weakness to venom, make sense, but others, like Mouse exploding if he takes one bite of cake, are just silly.
* In ''Film/NightOfTheDemons2009'', the demons are vulnerable to rust.
* ''Film/MontyPythonAndTheHolyGrail'': The Knights Who Say "Ni!" are sent into unbearable pain upon hearing the word "it".
* ''Film/{{Hungerford}}'': The [[BigCreepyCrawlies bugs]] don't like body spray. If a [[MindControl mind-controlled]] human host is sprayed, they'll fall to the ground, clutching their faces, and then the bug will leap out of their neck.
* ''Film/{{Peelers}}'': The infected can be killed with water. The apparent logic behind this is because the two substances are as incompatible as oil and water.
* ''Film/BlackSheep2007'': The were-sheep are horrible monsters. But they're mentally still sheep, so a single sheepdog is enough to contain them.
[[/folder]]

[[folder:Gamebooks]]
* The Darklords of the ''Literature/LoneWolf'' gamebooks are [[spoiler:(were, as of Book 12)]] crippled by ''clean air'' and can only unleash their full strength in toxic habitats. Half the reason they waged a centuries-long campaign ruining Magnamund (the other half being that they are AlwaysChaoticEvil embodiments of evil) is [[spoiler:(was)]] to make the world a paradise for themselves. Even in their weakened state they can still put up a good fight with their mastery of BlackMagic and immunity to conventional weapons. In one story arc, the Darklords develop a magical engine that allow them to retain their full strength outside their realm. [[spoiler:About a dozen of them are on the frontlines of their war when the protagonist smashes the engine, singlehandedly ending their reign of terror.]]
[[/folder]]

[[folder:Sports]]
* The MLB has starting pitcher Jon Lester. He's a three-time World Series winner, four-time All-Star, and a perennial Cy Young candidate. Only [[https://www.youtube.com/watch?v=cblrlzIxxfY he]] [[https://www.youtube.com/watch?v=pWM_rGr7A0w has]] [[https://www.youtube.com/watch?v=Sls10cwh6tw some]] [[https://www.youtube.com/watch?v=X_6Mvx6bQ5g trouble]] throwing to first base. Other players have had this problem at some point in their careers, such as pitchers Matt Young and Matt Garza, and second basemen Steve Sax and Chuck Knoblauch; catcher Mackey Sasser uniquely developed trouble throwing the ball back to the pitcher accurately. The term used for this in baseball is "The Yips."
* Also in baseball, we have knuckleball pitchers. Knuckleballs take relatively little force to throw and put little stress on a pitcher's joints. So, [[DifficultButAwesome once mastered]], knuckleball pitchers are virtually guaranteed long careers. The catch? The pitch is almost totally dependent on the pitcher's fingernails for control. So a broken nail or hangnail a standard pitcher might not even notice (or could handle with a simple bandage) can wreck a knuckleballer.
[[/folder]]

[[folder:Western Animation]]
* ''WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius'': In "Ultra Sheen", using his encyclopedic knowledge of [[ShowWithinAShow Ultra Lord]], Sheen remembers that his ArchEnemy [=RoboFiend=] has crippling lactose intolerance ([[RuleOfFunny despite being a robot]]). Spraying him with llama milk causes him to sneeze so hard he ''explodes''.
* One episode of ''WesternAnimation/{{Arthur}}'' revealed that [[ShowWithinAShow Bionic Bunny]]'s weakness is table salt. As soon as it contacts his skin, he loses his powers, retains water, and becomes grouchy.
* ''WesternAnimation/AvatarTheLastAirbender'': Element-bending is basically SupernaturalMartialArts combined with ElementalPunch, meaning that you can stop the craziest of superpowered benders by tying up their hands and legs. Though there are those with whom even ''that'' won't work [[spoiler: (Aang can blow people away with a sneeze, Iroh and Korra can breathe fire, Bumi can earthbend with his face, Yakone and Noatak have demonstrated psychic bloodbending, Combustion Man and P'li can blow things up by thinking at them, and Ming-Hua can waterbend despite having no arms]].
* In ''WesternAnimation/BatmanBeyond'', the assassin Inque is vulnerable to water, which dilutes her form so she can't stay in one piece and has to pull herself back together over time. Despite this, she's likely the strongest villain in the series (in terms of physical power), who has likely come closer to killing Terry than anyone else (even his ArchEnemy Blight), and while he has defeated her, he has ''always'' needed help from someone else to do so.
* ''WesternAnimation/BatmanTheBraveAndTheBold'': In "The Super-Batman of Planet X!", Batman is stranded on a strange, alien planet and teams up with the local near-identical Batman to foil crime. Then it turns out that thanks to the planet's atmosphere Batman becomes a FlyingBrick, much to the local Batman-X's chagrin. That is, until the [[KryptoniteIsEverywhere commonly occurring]] mineral ''Quartz'' renders him worse than powerless and allows Batman-X to save the day.
* ''WesternAnimation/Ben10'':
** In "The Galactic Enforcers", it turns out that the leader of the Galactic Enforcers (an alien superhero team, said leader an obvious parody of Superman) has a devastating weakness to chocolate, which [[LampshadeHanging Ben himself points out]] is a lame superweakness.
** In "Camp Fear", a fungus monster is killed using ordinary athletes' foot powder.
* ''WesternAnimation/Ben10UltimateAlien'' features in [[MonsterOfTheWeek the episode]] "The Big Story" an otherwise-invulnerable plant monster that ''dissolves'' on contact with... peanuts. No explanation is given beyond "it's allergic".
* WesternAnimation/{{Birdman|1967}} from the old Creator/HannaBarbera cartoons had the powers of flight, energy beams that shot from his hands, enhanced strength, and a personal force field -- and drew his powers from the light of the sun. Fair enough, there are plenty of other solar-powered heroes out there (Characters/{{Superman|TheCharacter}}, [[Characters/MarvelComicsCyclops Cyclops]] [[[DependingOnTheWriter sometimes]]], [[Characters/TeenTitansStarfire Starfire]]). Unlike those heroes, however, Birdman apparently had ''no'' energy reserve; he became weak as a baby after being removed from sunlight for ''less than a minute''. As it was implied that being out of the sun for an extended period of time ("extended" apparently being something like five minutes) was fatal to Birdman, it's a wonder he didn't spontaneously drop dead at night. [[WesternAnimation/HarveyBirdmanAttorneyAtLaw No wonder he became a lawyer.]] After he became a lawyer, he developed a new Weaksauce Weakness; he's completely worthless if he loses the Birdman insignia that he keeps on his forehead.
* In one episode of ''WesternAnimation/TheBotsMaster'', the BigBad uses a special alloy to make his MechaMooks [[NighInvulnerability nigh-invulnerable]]. The good guys think that they're screwed, until the inventor of the alloy tells them that the alloy can be dissolved by...''citric acid''. In the end they use ''lemon juice'' to defeat the new MechaMooks.
* ''WesternAnimation/BureauOfAlienDetectors'': When making an unstoppable zombie army, it's a good idea to ensure that the one thing that will kill them doesn't exist naturally in the atmosphere. [[spoiler:Oxygen.]]
* ''WesternAnimation/CaptainPlanetAndThePlaneteers'':
** Being a paragon of clean Earth, Captain Planet is weak against your usual forms of pollution (smog, toxic waste, etc.), as well as Hitler-level hatred, apparently. You might consider these not particularly weaksauce, but it suggests Gaia went seriously wrong in the design stage: the things he was created to fight against are the things that do him the most damage. It's like J'onn J'onnz deciding to be a firefighter or Alan Scott deciding to only fight evil loggers.
** The Planeteer's individual rings also ([[DependingOnTheWriter occasionally]]) don't work when there is too much pollution, which again brings up several questions regarding Gaia's design philosophy for the weapons of her pollution fighting champions.
** His EvilCounterpart Captain Pollution has an even lamer weakness: direct sunlight, lack of pollution, and ''clean water.'' Yes, any remotely clean source of drinking water sprayed in his face will make him bow down and crawl helplessly. This seriously deters his ability to establish himself as a credible threat.
* Namor the Sub-Mariner of Creator/MarvelComics is similarly affected by pollution (though not by hate, which is good, since he seems to run on it), but that makes sense, as he's a water-breather. Because he's a HalfHumanHybrid, he's also subject to insanity and fits of rage if he stays submerged for more than two weeks. Or emerged for more than two weeks. So he needed to switch environment every week to stay sane. Until authors simply forgot the issue.
* In the ''WesternAnimation/CatDog'' episode "Greasers in the Mist", where [=CatDog=] has Lola Caricola infiltrate the Greasers to try and learn about their weaknesses, everyone refers to this trope as "Porkfat", named after the weaksauce weakness of the in-universe movie character, Mean Bob.
* ''WesternAnimation/CodenameKidsNextDoor'': The Kids overcome Father's pyrokinesis by drenching him in ice cream. (Oddly enough, he still eats it from time to time, especially when he's depressed.)
* ''WesternAnimation/DannyPhantom'':
** Desiree's main weakness is that she has to grant ''every'' wish she hears, including wishes like "I wish you were defeated." She even says "I... I must obey!"
** The Fright Knight is also stupidly vulnerable. If his sword gets sheathed in a pumpkin, he is instantly defeated. His worst nightmare is probably somebody using an ordinary pumpkin as a shield.
* ''WesternAnimation/DarkwingDuck'':
** Not exactly canon, but when he retells his origins in "The Secret Origin of Darkwing Duck," he describes meeting another hero whose weakness is Coo-koo Cola. She winds up falling into a vat of the stuff at a factory and, well... adds to the Disney series' death count. Then again that story's complete baloney (to name but one problem, that hero was played by Gosalyn and Launchpad was her sidekick, neither of whom Darkwing met until after they'd been active for a while), so it only counts for invoked in a ShowWithinAShow.
** There's also Comet Guy (SuperWeight: 4), whose AchillesHeel is that every time he hears the sound of a bell, he starts dancing mindlessly until he hears a whistle. His intellect might also count, but frankly it probably can't even do 2+2. Darkwing teaches him to work around the bell problem by [[spoiler:via becoming a DanceBattler]].
* ''WesternAnimation/TheFairlyOddParents'':
** All that fairy magic is neutralized when they are under a butterfly net. There's also all the various "Da Rules" which prevent them from undoing some of the more disastrous wishes, but do nothing to stop them from getting into these situations to begin with. One thinks an "I wish that no wishes that will somehow prevent me from ''undoing'' those wishes can be cast" wish might save a lot of trouble.
** Despite all their bluster of being strong, the Yugopotamians have a huge weakness- they’re terrified of anything considered cute, happy, or saccharine. This comes up in several episodes featuring them, where they panic and stop fighting every time they encounter something that falls into that description. In one episode, for example, they challenge Timmy to eat a bar of chocolate, something they consider the most lethal poison in existence, and they pass out in fright when he easily does so.
* Parodied in an episode of ''WesternAnimation/{{Freakazoid}}'', where Gutierrez confronts Freakazoid armed with a small collection of famous Weaksauce Weaknesses like [[Franchise/{{Superman}} a chunk of kryptonite]], a [[Franchise/GreenLantern gold card]] and [[Film/TheWizardOfOz a glass of water]]. Then he finds out that his weakness is actually [[SubvertedTrope graphite bars charged with negative ions]]. And "[[{{Fartillery}} poo-gas]]" (but then again, nobody likes poo-gas.)
* Spoofed in ''WesternAnimation/{{Futurama}}'' where some robots are watching B-grade monster movie where the monster is a human who is "[[ImmuneToBullets impervious to their most powerful magnetic rays]]", yet can be brought down by a simple [[WoodenStake sharpened stick]].
** ''Film/TheWizardOfOz'' parody in "Anthology of Interest II" spoofs that movie's witches' [[KillItWithWater melting when they touch water]], having both Mom and [[spoiler:Leela]] as witches who predictably end up splashed with a small amount of liquid and melt away.
* ''WesternAnimation/{{Gargoyles}}'':
** The titular creatures [[TakenForGranite turn into immobile statues]] during the day, which leaves them extremely vulnerable. They try to work around this in various ways (working a deal with humans in exchange for protection, magic spells, etc.) However, this is actually a bit of a double-edged sword. Though vulnerable as stone statues, they are COMPLETELY healed of almost ANY wounds (even potentially fatal ones) when they return to flesh and blood. Hudson, being the most experienced of the main cast, uses this to his advantage, defeating the better armed and fitter Demona while protecting an injured Goliath by simply keeping her at bay until dawn. When the sun sets, Goliath is healed and they easily dispatch her together.
** Oberon's Children, like other portrayals of TheFairFolk, are all vulnerable to iron. Iron can disrupt their magic, actually ''hurt'' them, and imprison them. In his [[spoiler: not really]] first appearance, Puck is forced to obey Demona after being bound with iron chains. The Weird Sisters are also coerced into doing a favor in exchange for being released from an iron chain. Later, TricksterGod Coyote is trapped in the ''robot'' Coyote's latest body which was constructed with iron from a magical cauldron. Their ruler Oberon, while not immune to iron, is powerful enough to withstand being ''impaled by an iron harpoon'' though it does cause him to wither in appearance for a short time. ([[spoiler:Ringing an iron bell]] defeated him in his first appearance, but then, [[WillfullyWeak this was after he purposely reduced his power]].)
* According to ''WesternAnimation/GodTheDevilAndBob'', Satan can't stand Tony Orlando songs. This comes in handy the one time he actually tries to knock off the comedy routine and physically attack Bob.
* Mighty Ray of ''WesternAnimation/{{Hero 108}}'' has the ability to shoot lightning from his eyes. The drawback is that he has to eat a banana to do it...and he ''hates'' bananas. He can also have his eyes knocked out of his head, which happens more often than you'd like to think.
* Zim of ''WesternAnimation/InvaderZim'' is a member of a hyper-advanced, [[GeneticEngineeringIsTheNewNuke genetically engineered]] race of aliens for whom {{Humongous Mecha}}s are a mundane occurrence and whose sole purpose seems to be conquering the entire universe. His main weakness? Water (possibly just polluted water) and ''meat''.
* ''WesternAnimation/JackieChanAdventures'':
** In the season 4 premiere, Tohru threw an onion at Tarakudo on the strength of his mother's fairy tales about onions repelling oni. Tarakudo screamed about his eyes burning and vanished. Several episodes in we get Jade digging an onion out of a dumpster.
--->'''Tarakudo:''' No! Anything but onions! ''(Jade throws it at him.)'' My eyes! My eyes! ''(poof)''
** A one-off villain could be turned to stone if exposed to salt.
* ''WesternAnimation/JimmyTwoShoes'': According to WordOfGod, Lucius actually has some pretty terrifying powers, including RealityWarper abilities. The sole reason he doesn't use them is because his {{pride}} would be wounded if he admitted he needed them. Without them, he becomes a rather HarmlessVillain.
* ''WesternAnimation/JusticeLeague'':
** The Imperium, White Martian expys in ''WesternAnimation/JusticeLeague'' have an even greater weakness than the usual fire. Direct sunlight causes them to burn and evaporate near instantly. One would think they'd be moving along planet systems ''away'' from suns, but no.
** Alan Scott's weakness to wood was parodied in the ''WesternAnimation/JusticeLeague'' [[UsefulNotes/TheGoldenAgeOfComicBooks Golden Age]] AffectionateParody episode "[[Recap/JusticeLeagueS1E18And19Legends Legends]]", with his [[CaptainErsatz stand-in version]] "Green Guardsman", who had a weakness to aluminum. Either way, you've got a superhero who could appear on the news after having been beaten to death with a baseball bat -- and considering that one of his foes was the Sportsmaster, who ''did'' wield a baseball bat... it's pretty darned weaksauce.
* ''WesternAnimation/{{Kaeloo}}'': One of Mr. Cat's biggest weaknesses is [[spoiler: "zumba with friends"; that is, if his friends turn on zumba music and dance, he starts [[InvoluntaryDance involuntarily dancing along with them]] and is forced to stop doing anything else he might be doing at the moment]].
* ''WesternAnimation/KimPossible'':
** Felix Renton's SuperWheelchair is one of the most advanced pieces of technology in the series. It can hover and has CombatTentacles. But it can be hijacked by a ''wireless game controller''.
** One of [[MadScientist Dr. Drakken's]] schemes was to create an army of [[EvilKnockoff Kim Possible clones]]. The scheme failed when Wade figured out that the clones were chemically unstable and would melt if exposed to carbonated soda.
** In ''[[WesternAnimation/KimPossibleMovieSoTheDrama So The Drama]]'', Drakken created a synthodrone that could [[RidiculouslyHumanRobots pass for human]]. It [[NearVillainVictory blocked Kim's last-ditch attempt to stop Drakken]]... until one bite from Rufus drained its synthogoo and destroyed it.
* The controversial ''WesternAnimation/LooneyTunes'' short "Injun Trouble" (and its 1945 color remake "WesternAnimation/WagonHeels") features [[BraidsBeadsAndBuckskins Injun Joe]], [[BadassNative The Superchief]] as its villain. Injun Joe is a powerhouse; he shatters mountains and laughs at gunfire. But Porky Pig's sidekick Sloppy Moe knows Injun Joe's secret weakness: he's ticklish!
* ''WesternAnimation/LucyTheDaughterOfTheDevil'':
** Not only is vampires' weakness to sunlight so great that they can be turned to dust by UV fluorescent lights, but they're deathly afraid of ''balloons''.
** And when Senator Whitehead turns into a [[AttackOfThe50FootWhatever giant monster]], his weakness is beatboxing.
* An episode of ''WesternAnimation/MartinMystery'' had an alien fungus monster that had taken over a small town and replaced the inhabitants with clones. Both it and the clones could be killed with salt. As luck would have it, the small town just happened to be in [[http://en.wikipedia.org/wiki/Great_Salt_Lake northern Utah.]]
* The second act of the ''WesternAnimation/MrBogus'' episode "[[Recap/MrBogusS2E6TotallyBogusVideo Totally Bogus Video]]" showed that the Dirt Dudes are vulnerable to fruit punch, as it causes them to melt when it comes in contact with them, a la [[Film/TheWizardOfOz the Wicked Witch of the West]].
* ''WesternAnimation/MyLifeAsATeenageRobot'':
** "This Time With Feeling" has an incredibly powerful, sadistic, and sexist supervillain, Himcules, who gets stronger and stronger anytime he hurts or humiliates someone. And of course, he appears right after Jenny has implanted sensors in herself that either tickles herself or causes her pain. Stuck in "Pain" mode, Himcules continues to gain more and more muscle (and even pleasure) every second he makes her cry in pain... then she comes upon a little girl who kindly (sorta) switches her "Pain" switch to "Tickle", and it just so happens that laughing at Himcules is his only weakness.
** Another example would probably be Jenny herself. She’s a powerful crime-fighting robot whose only weakness is [[NoWaterProofingInTheFuture ...water]].
* In what might be one of the most literal examples of this trope, ''WesternAnimation/TheNewScoobyAndScrappyDooShow'' episode "Scooby's Gold Medal Gambit" featured a villain known as Chameleon who was a MasterOfDisguise, capable of disguising himself so flawlessly as to be completely unrecognizable. His one flaw? He hated Worcestershire sauce. So much that whenever someone so much as ''mentioned'' the condiment, he felt compelled to break character to scream about how much he hated Worcestershire sauce.
* In the ''WesternAnimation/PlanetSheen'' episode "To Chill a Mocking Blurg", the Blurgs explode after being complimented.
* ''Franchise/ThePowerpuffGirls'':
** When Buttercup wanted to become a better superhero in "SuperZeroes", she became Mange, a knockoff of DarkerAndEdgier comic book {{Anti Hero}}es -- Comicbook/{{Spawn}} in particular. However, when the time came for her and her sisters (both of whom also assumed their own "better superhero" identities) to go out and fight a monster destroying Townsville, Mange was the only one who stayed behind, saying it's too bright and that she only travels at night. Mange then spent the rest of the day sitting on the couch with Professor Utonium until night fell, arriving too late at the scene as the monster had already left (her sisters were also late for reasons of their own). The three girls spent the night under a tree. When the monster came back to face the girls again, Mange sits out the fight, preferring to stay under the tree's shade. This attitude led the monster to eventually call her "Little Miss Darkness who’s afraid of a little sun".
** Being kindergarteners, the girls have plenty of weaknesses of their own any other time--they have been shown to be deathly afraid of "cooties", cockroaches, and broccoli. The episodes these weaknesses show up in usually involve [[MonsterOfTheAesop some sort of super-powered or evil version of it]], so it's not always so silly...
** There's Antidote X which was used in only one television episode ("Slumbering With The Enemy", on the girls themselves) and in the movie (on Mojo Jojo). Mojo also tried to use it in another episode where he also used Chemical X to give his then-partner Princess super-powers. Unfortunately, this backfired on ''both'' villains, and Princess was hit with the Antidote X, letting the Girl trounce them both.
** The original incarnation of their [[DistaffCounterpart Spear Counterpart]] enemies the Rowdyruff Boys [[spoiler:are so grossed out by the girls' kisses that they explode]]. And after being genetically modified to actually gain strength from this past weakness ([[spoiler: aka puberty]]), they gain a new weakness, [[spoiler: humiliation. Yes, humiliation. Anytime they are embarrassed and laughed at, or "[[DoesThisRemindYouOfAnything whenever their masculinity is threatened]]", they shrink]].
* The ''WesternAnimation/SheepInTheBigCity'' episode "Fleeced to Meet You" had a sketch where the superhero Completely Powerful Guy is informed by his sidekick Wonderful Boy that there are various criminals on the loose that he's expected to stop. Completely Powerful Guy claims that the villains' various attacks, such as using dynamite, pollen, or even tickling, are his most dangerous vulnerabilities, though it's implied that he's just making up excuses to avoid going after the crooks. [[WhatTheHellHero Wonderful Boy rightly calls Completely Powerful Guy out on avoiding going after the criminals with the flimsy excuse that they could easily hurt him]].
* ''WesternAnimation/SpongeBobSquarePants'':
** The alien jellyfish in the episode "Planet of the Jellyfish" dissolve into puddles of goop upon contact with mayonnaise.
** One of Mermaid Man and Barnacle Boy's antagonists is the Dirty Bubble, who is... a bubble. Go ahead, guess a weakness.
* If WesternAnimation/{{SheZow}} gets her hair messed up, she loses her power -- fortunately for her, [[CrazyPrepared she has a can of hair spray in the Beautility Belt to fix this]].
* ''WesternAnimation/SupermanTheAnimatedSeries'': Mr. Mxyzptlk is [[RealityWarper so powerful]] that he has no natural weaknesses. To make his fights with Characters/{{Superman|TheCharacter}} more challenging, [[SelfImposedChallenge he gives himself one]]. Which one does he choose? Saying his own name backwards. Used hilariously in "Mxyzpixilated" with Superman using clever and creative ways of exploiting Mr. Mxyzptlk's "weakness", often without having to use any sort of super powers at all. In one, Clark tells Mxyzptlk he can't "play" until he finishes proof-reading a paper. Mxyzptlk grabs it and uses magic to cross out all the typos. Three guesses what they spell.
* The members of the WesternAnimation/SushiPack are rendered powerless by any kind of heat, but even worse, they feel compelled to announce this every time a villain pulls out a heat lamp.
* In the ''WesternAnimation/{{Talespin}}'' episode, "Pizza Pie in the Sky", the normally healthy and active Louie is severely allergic to anchovies. One whiff of the irregular anchovies that Baloo and Kit bring him is enough to make him ill and delusional.
* In ''[[WesternAnimation/TeenageMutantNinjaTurtles2003 Teenage Mutant Ninja Turtles: Fast Forward]]'' Sh'Okanabo's first attempt to infect Earth with his [[TheVirus progeny]] is thwarted by...sunlight. Although this is handwaved as a particular, unexpected feature of Earth's, and Sh'Okanabo himself is not normally affected, dealing with his weakness is the thrust of his character arc throughout the remainder of the season.
* ''WesternAnimation/ThunderCats1985'':
** [[BigBad Mumm-Ra]] had a weakness to ''his own reflection''. The writers eventually realized this made Mumm-Ra too lame, so they had him get over it. The Thundercats had a harder time dealing with him after that. Even more so when he got an InfinityPlusOneSword of his own.
** [[WalkingWasteland Plutar]] was weakened by soap. The show was so far in the future that modern society was all but forgotten; soap was treated as an ancient science.
* In ''WesternAnimation/TheTransformers'', the Decepticons were once driven off by a fire suppression system that sprayed them with fire-retardant foam after Megatron claimed it would short out their circuits. Why this doesn't make Inferno and Hot Spot (Autobots who turn into fire trucks) into the Decepticons' primary nemeses has never been explored. In what may be a weird mixture of CallBack and RunningGag, Sideways in ''Anime/TransformersCybertron'' and Starscream and Blackarachnia in ''WesternAnimation/TransformersAnimated'' have also been incapacitated by fire-retardant foam for varying lengths of time. This includes the foam from a traditional human-sized fire extinguisher, in the case of Sideways.
* In ''WesternAnimation/WanderOverYonder'' the extremely powerful Lord Dominator has only two weaknesses; being cut off from the armor that provides her powers (understandable and not often a problem) and, far more embarrassingly, [[spoiler: a severe allergy to ''pollen'']]. In the second-to-last episode of season 2 this leads to her humiliatingly defeating herself by [[spoiler: picking up a flower]].
* WesternAnimation/WordGirl isn't so much defeated by a cute little kitten, but rather [[CutenessProximity easily distracted by one]]. She also compensates for her language abilities by showing a complete lack of competence in art, poetry, and dance.
* ''WesternAnimation/YinYangYo'':
** The only thing that prevents Brother Herman from [[TakeOverTheWorld taking over the world]] is the fact the he's allergic to panda fur. As long as Master Yo, [[LastOfHisKind the last panda on the planet]], is around, [[FailureIsTheOnlyOption failure will be his only option]].
** His brother Carl, The Evil Cockroach Wizard has been shown to be a very powerful villain capable of [[TakeOverTheWorld global domination]] himself, but he has one glaring weakness: self-esteem. He's been defeated by insults and peer pressure, and his own low opinion of himself keeps him from going full-tilt against the heroes and his brother.
* ''WesternAnimation/{{Zeroman}}'s'' weakness is anti-static sheets, which mess with Zeroman's suit's systems.
[[/folder]]

* The film adaptation of ''Literature/TheSpiderwickChronicles'' gives the villains several Weaksauce Weaknesses they didn't have in the original books:

Subtropes include:

!!Examples:

* ''Film/TheSpiderwickChronicles'' provides a literal weak''[[{{Pun}} sauce]]'' weakness: Tomato sauce is corrosive to goblins. (This was not in the original book.)

** Another example would probably be Jenny herself. She’s a powerful crime-fighting robot who’s only weakness is [[NoWaterProofingInTheFuture ...water]].

[[folder:Film — Animation]]

* Invoked by Syndrome in ''WesternAnimation/TheIncredibles'' with the Omnidroid. It was built for an EngineeredHeroics scheme, so he designed it to be [[NighInvulnerability nigh-invulnerable]] and unstoppable... to anything ''except'' the remote control that Syndrome wore on his wrist. [[spoiler: It doesn't end well for him when the Omnidroid's adaptive A.I. [[GoneHorriblyRight adapts to cover for that weakness]], but it does eventually allow the heroes to win, after a period of desperately playing keep-away while the Omnidroid attempted to destroy the remote.]]

[[folder:Film — Live-Action]]

* [[OurFairiesAreDifferent Fairies]] from ''LightNovel/HumanityHasDeclined'' are killed by EM waves, a.k.a. light, the most ubiquitous thing in the universe. If the setting wasn't AfterTheEnd, they'd be screwed, and they still have problems with it anyway.

** In-universe, at least, we have Enel. His ShockAndAwe abilities are considered among the most godlike Devil Fruit powers in the setting, yet Luffy's relatively low-tier RubberMan powers completely and utterly negated them, to the point that Eneru had to get really creative with his powers just to find a way to harm Luffy at all, and only his unrelated CombatClairvoyance protected him from getting beaten to a pulp pretty much instantly.

* Tobor, the Anime/EighthMan, recharged his powers with an inhalant stored in small, thin, white tubes that he carried in a cigarette case. When the bad guys allowed him "one last smoke" before executing him, this was great; when he was having a fight where kids could see him, he worried about setting a bad example by appearing to smoke.

* In ''Anime/CowboyBebop'', Pierrot le Fou a.k.a. Tongpu is a psychotic, unstoppable, bulletproof Psychopathic Manchild. He has exactly two weaknesses, both psychological: A pathological fear of cats due to the experiments that he was subjected to, and [[spoiler: feeling pain, induced in this case by Spike hurling a knife (a projectile too slow to be stopped by Pierrot's experimental shield) into his thigh]].

* ''LightNovel/{{Durarara}}'':

*** [[spoiler:If someone can get her angry enough, such as in the case of Kasane possessing Shinra, Celty will almost instantly turn into an amorphous, insentient monster]].

* Fairies from ''LightNovel/HumanityHasDeclined'' are killed by EM waves, a.k.a. light, the most ubiquitous thing in the universe. If the setting wasn't AfterTheEnd they'd be screwed. And theystill have problems with it anyway.

** Some powerful Stands also incorporate this trope for narrative balance reasons. One key example is [[Manga/JoJosBizarreAdventureDiamondIsUnbreakable Part Four's]] Red Hot Chili Pepper. Since it becomes stronger and faster the more electricity it has access to, with no stated or hinted upper limit, it can be said to be one of the most powerful stands in Part 4. But this comes with two weaksauce weaknesses; first, if you cut off its access to electricity, say, by destroying the motorcycle battery it was hiding in, it rapidly weakens and fades. Second, since salt water is such an excellent conductor, immersing it in the ocean will cause it to rapidly dissolve.

** ''Manga/StoneOcean'' has Ungalo's Stand, Bohemian Rhapsody, which has the incredible power to ''cause every single fictional character ever written to come to life''. On top of that, anyone who identifies with that character will [[YouCantFightFate be doomed to replace them and suffer the character's fate]]. This causes massive devastation across the entire world (for example, characters from ''Manga/FistOfTheNorthStar'' destroy Tokyo while reenacting their battle)... until Weather Report easily stops it dead in its tracks by creating an original character named Put-Back, who returns all of the summoned characters to their stories. As a side-effect, this also permanently renders Bohemian Rhapsody completely unusable, since any future attempts at reactivating its ability would also summon Put-Back, immediately cancelling it. Ungalo [[DespairEventHorizon instantly loses all will to live and falls into a coma]] upon realizing this.

* In one episode of ''LightNovel/MyriadColorsPhantomWorld'', the team are pitted against a [[{{Youkai}} Youkai Phantom]] in the form of a sunflower. They can't beat him until Koito works out that [[LogicalWeakness because he's a sunflower, he can only face towards the sun]]. They therefore defeat him by simply walking round him and attacking from behind, where he can't see or reach them.

* In ''LightNovel/{{Slayers}}'', female spell-casters have a very common and mundane weakness: menstruation. During a woman's menstruation period, her magical power output drops tremendously, so much so that even the protagonist, Lina Inverse, who is one of the strongest sorceresses in the entire Slayers setting, is barely able to cast a novice ''Light'' spell during her period. This is apparently a well-known weakness, as Zelgadis and even [[IdiotHero Gourry]] both figure out why her powers are weakened at one point, though Gourry is so ignorant that he doesn't understand the significance of "that time of the month" and just assumes it's magic-related.

* ''TabletopGame/BlackbirdsRPG'': ''TabletopGame/BlackbirdsRPG'': All of the [[OurDemonsAreDifferent Outsiders]] that Theurges can summon to perform feats of magic have some kind of weakness that prevents them from using their powers. Some of these make sense -- such as an Outsider who manifests in reflections needing a nearby reflective surface in order to appear -- but others are very random. Examples include Tabernacle, who is banished if doused in egg yolk; Asisaxasias, who refuses to manifest in the presence of [[CatsAreMagic cats]] and whose powers do not affect felines; and Father Longlegs, who will hide in a corner until sundown if he witnesses [[AllergicToLove a sincere act of physical affection]].