History Main / ProfessorGuineaPig

18th Sep '16 3:59:45 PM ChaoticNovelist
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Believe it or not, [[TruthInTelevision this was actually standard procedure]] in many fields of science until fairly recently. Even as late as the 1950's, chemists would create a new compound and ingest it to see what it did. It was not the healthiest of occupations; quite a few scientists did end up killing themselves via experimentation. The Nuremberg Code of 1946, which codified the ethical requirements for human experimentation, forbids any experiments that is highly likely to or will certainly cause death or serious harm to the subjects. However, the ban is '''explicitly waived''' if the researcher is experimenting on himself. It's still sort-of common; see the real-life examples down below.

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Believe it or not, [[TruthInTelevision this was actually standard procedure]] in many fields of science until fairly recently.science. Even as late as the 1950's, chemists would create a new compound and ingest it to see what it did. It was not the healthiest of occupations; quite a few scientists did end up killing themselves via experimentation. The Nuremberg Code of 1946, which codified the ethical requirements for human experimentation, forbids any experiments that is highly likely to or will certainly cause death or serious harm to the subjects. However, the ban is '''explicitly waived''' if the researcher is experimenting on himself. It's still sort-of common; see the real-life examples down below.



*''Literature/JourneyToChaos'': Ginger Hasina is a healer who makes experimental remedies. One of them was an anthrax vaccine that she tried on herself. When Eric enters her office late at night, she thinks auditory and visual hallucinations are side effects.



** Exactly the same thing happens in the Sixties TimeTravel show ''Series/TheTimeTunnel''.

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** Exactly the same thing happens in the Sixties TimeTravel show ''Series/TheTimeTunnel''.%%*''Series/TheTimeTunnel''.



* Subverted in ''Series/PowerRangersDinoThunder'' where Dr. Anton Mercer tries and tries to perfect a potion to free himself from his SuperpoweredEvilSide Mesogog, where Mesogog actually succeeds in perfecting the potion and capturing the scientist.
** Of course, Mercer experimenting on himself was what ''created'' Mesogog in the first place.

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* Subverted in ''Series/PowerRangersDinoThunder'' where Dr. Anton Mercer tries and tries to perfect a potion to free himself from his SuperpoweredEvilSide Mesogog, where Mesogog actually succeeds in perfecting the potion and capturing the scientist.
**
scientist. Of course, Mercer experimenting on himself was what ''created'' Mesogog in the first place.



* The inventor of cardiac catheterization did the [[http://en.wikipedia.org/wiki/Werner_Forssmann first one to himself]], with an x-ray to prove it. He even tied his assistant to a table to prevent him from interfering after everyone told him the procedure was insane. He survived the procedure and eventually ended up with the Nobel Prize.
** No that's incorrect. The actual story is even crazier. It was a nurse who volunteered to be the Guinea Pig. So he sedated her, turned around, and then did the procedure on himself. [[{{Website/Cracked}} That's right. The man stabbed himself in the heart as a slight of hand trick, thereby permanently upstaging David Copperfield years before he was even born.]] And then he walked all the way to the X-ray room while holding the cable. When one of colleagues tried to pull it out as he thought the man was crazy, Werner kicked him in the chest.
* [[http://en.wikipedia.org/wiki/John_Stapp Colonel John Paul Stapp]] (M.D., Ph.D) was an aeronautics expert involved in testing the limitations of the human body in high speed flight at the dawn of the jet age. Due to the lack of crash test dummies that could accurately model the human body or report on how they felt, Col. Stapp offered his services as a substitute. In 1947 the conventional wisdom that forces greater than 18G would prove fatal. After numerous tests in [[RocketRide rocket powered contraptions]] Col. Stapp shattered this barrier and eventually reached 46.2G, a record which stands to this day as the highest g-forces ever '''''voluntarily''''' experienced by a human being.
** Predictably, Stapp suffered repeated and various injuries including broken limbs, ribs, detached retina, and miscellaneous traumas which eventually resulted in lifelong lingering vision problems caused by permanently burst blood vessels in his eyes.

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* The inventor of cardiac catheterization did the [[http://en.wikipedia.org/wiki/Werner_Forssmann first one to himself]], with an x-ray to prove it. He even tied his assistant to a table to prevent him from interfering after everyone told him the procedure was insane. He survived the procedure and eventually ended up with the Nobel Prize.
** No that's incorrect. The actual story is even crazier. It was a
A nurse who volunteered to be the Guinea Pig. So Pig so he sedated her, turned around, and then did the procedure on himself. [[{{Website/Cracked}} That's right. The man stabbed himself in the heart as a slight of hand trick, thereby permanently upstaging David Copperfield years before he was even born.]] And then he walked all the way to the X-ray room while holding the cable. When one of colleagues tried to pull it out as he thought the man was crazy, Werner kicked him in the chest.
* [[http://en.wikipedia.org/wiki/John_Stapp Colonel John Paul Stapp]] (M.D., Ph.D) was an aeronautics expert involved in testing the limitations of the human body in high speed flight at the dawn of the jet age. Due to the lack of crash test dummies that could accurately model the human body or report on how they felt, Col. Stapp offered his services as a substitute. In 1947 the conventional wisdom that forces greater than 18G would prove fatal. After numerous tests in [[RocketRide rocket powered contraptions]] Col. Stapp shattered this barrier and eventually reached 46.2G, a record which stands to this day as the highest g-forces ever '''''voluntarily''''' experienced by a human being.
**
being. Predictably, Stapp suffered repeated and various injuries including broken limbs, ribs, detached retina, and miscellaneous traumas which eventually resulted in lifelong lingering vision problems caused by permanently burst blood vessels in his eyes.



* The Nuremberg Code, formulated after the trials of the concentration camp "doctors," expressly forbids any form of human experimentation unless the doctors in question experiment on themselves - and treats even that exception as being ethically and morally dubious. No country has ever adopted the Nuremberg Code in its entirety.
** However, all countries did adopt the Declaration of Helsinki, as mandated by the WHO, which is more practical and easier to work with for scientists and doctor.

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* The Nuremberg Code, formulated after the trials of the concentration camp "doctors," expressly forbids any form of human experimentation unless the doctors in question experiment on themselves - and treats even that exception as being ethically and morally dubious. No country has ever adopted the Nuremberg Code in its entirety.
**
entirety. However, all countries did adopt the Declaration of Helsinki, as mandated by the WHO, which is more practical and easier to work with for scientists and doctor.
21st Aug '16 8:04:39 PM CompletelyNormalGuy
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** Oddly a striking number of H-manga and doujins parody, lampshade and even deconstruct tropes from either the source material or from hentai in general. It's typically done to further the sex (mind control? why of course I'd go crazy and turn the world into my harem) or simply to break the tension by pointing out how weird the plots can get.



* Kurotsuchi Mayuri of ''Manga/{{Bleach}}'' is obviously his own favorite test subject (he's given himself such bizarre abilities as being able to rip out his own ear and transform it into a [[http://en.wikipedia.org/wiki/Kusarigama kusarigama]], and to [[RocketPunch launch his right arm as a grappling hook]])...although based on what is known of his personality, most of his "improvements" were probably perfected on the unwilling first.

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* ''Manga/{{Bleach}}'':
**
Kurotsuchi Mayuri of ''Manga/{{Bleach}}'' is obviously his own favorite test subject (he's given himself such bizarre abilities as being able to rip out his own ear and transform it into a [[http://en.wikipedia.org/wiki/Kusarigama kusarigama]], and to [[RocketPunch launch his right arm as a grappling hook]])...although based on what is known of his personality, most of his "improvements" were probably perfected on the unwilling first.



* In ''Manga/SoulEater'', one of the first things we learn about Franken Stein is that he is interested in observation and experimentation, where anything or one could be a test subject -- including himself. Stein has, naturally, a bolt through his head and scars all over him.
** Sort of an odd example though in that we don't actually know what he did to himself. Yes, he has a stitch over his face but aside from that he doesn't look too different from his younger incarnation we see in flashbacks so it at least wasn't anything cosmetic. He's been hailed as a genius meister since before he had the scar and bolt too so it wasn't some kind of power augmentation. So far the bolt and scar on his face only seem to be evidence that he has done this, but the reason behind it has not yet been given.

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* In ''Manga/SoulEater'', one of the first things we learn about Franken Stein is that he is interested in observation and experimentation, where anything or one could be a test subject -- including himself. Stein has, naturally, a bolt through his head and scars all over him.
**
him. Sort of an odd example though in that we don't actually know what he did to himself. Yes, he has a stitch over his face but aside from that he doesn't look too different from his younger incarnation we see in flashbacks so it at least wasn't anything cosmetic. He's been hailed as a genius meister since before he had the scar and bolt too so it wasn't some kind of power augmentation. So far the bolt and scar on his face only seem to be evidence that he has done this, but the reason behind it has not yet been given.
6th Aug '16 9:12:28 AM narm00
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* Lampshaded in ''ComicBook/BlueBeetle''. When Dan Garrett (having recently switched meds) decides to fly Jaime and herself into a volcano the following exchange occurs:

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* Lampshaded in ''ComicBook/BlueBeetle''. When Dan Dani Garrett (having recently switched meds) decides to fly Jaime and herself into a volcano the following exchange occurs:



-->'''Dan''': Only one way to find out!

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-->'''Dan''': -->'''Dani''': Only one way to find out!



-->'''Dan''': Oh, yeah. Whoops.

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-->'''Dan''': -->'''Dani''': Oh, yeah. Whoops.



* In ''Film/TheFly1958'', the lead character tries teleporting himself, winds up switching heads with a housefly. [[Film/TheFly1986 The 1986 remake]] rationalized this simply enough -- [[AlcoholInducedIdiocy he was drunk at the time,]] having just rowed with his love interest. Mind you, he had already tested the thing with a monkey with no ill effects.

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* In ''Film/TheFly1958'', the lead character tries teleporting himself, and winds up switching heads with a housefly. [[Film/TheFly1986 The 1986 remake]] rationalized this simply enough -- [[AlcoholInducedIdiocy he was drunk at the time,]] having just rowed with his love interest. Mind you, he had already tested the thing with a monkey with no ill effects.



* Victor in ''{{Film/Upldr}}'', used himself as a test subject on a way to upload and download information directly from the human brain.

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* Victor in ''{{Film/Upldr}}'', ''{{Film/Upldr}}'' used himself as a test subject on a way to upload and download information directly from the human brain.



* In fact, it shows up in a lot Creator/HGWells stories, period. Another example is ''The New Accelerator'', in which he tests out a drug on himself that makes him speed up by a factor of several thousand.
* Another classic example is ''Literature/TheStrangeCaseOfDrJekyllAndMrHyde'' and all the variations thereof, e.g. ''TheNuttyProfessor''.

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* In fact, it shows up in a lot of Creator/HGWells stories, period. Another example is ''The New Accelerator'', in which he tests out a drug on himself that makes him speed up by a factor of several thousand.
* Another classic example is ''Literature/TheStrangeCaseOfDrJekyllAndMrHyde'' and all the variations thereof, e.g. ''TheNuttyProfessor''.''Film/TheNuttyProfessor''.



* ''Literature/TwentyThousandLeaguesUnderTheSea'': In a variation, TheProfessor Aronnax is willing to sacrifice his own freedom for the rest of his life [[ForScience for the rare chance to discover all the seaís secret in the Nautilus]]. Fortunately, he is not [[GuineaPigFamily willing to sacrifice his friendís freedom]] and leads them in their GreatEscape.

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* ''Literature/TwentyThousandLeaguesUnderTheSea'': In a variation, TheProfessor Aronnax is willing to sacrifice his own freedom for the rest of his life [[ForScience for the rare chance to discover all the seaís secret secrets in the Nautilus]]. Fortunately, he is not [[GuineaPigFamily willing to sacrifice his friendís freedom]] and leads them in their GreatEscape.



* In the third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and injects it into himself. He gets insect-like super-strength, agility, and wall-climbing ability, but as a side effect appears to be mutating uncontrollably. The entire plot line appears to be a direct reference to the 1986 version of ''TheFly''.

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* In the third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and injects it into himself. He gets insect-like super-strength, agility, and wall-climbing ability, but as a side effect appears to be mutating uncontrollably. The entire plot line appears to be a direct reference to [[Film/TheFly1986 the 1986 version version]] of ''TheFly''.''The Fly''.



* Semi-averted in an episode of ''Series/TheSaint'', where a man with a heart condition wanted to use cryogenics until open heart surgery was commonplace. He did several animal testing, and ''wanted'' to start human testing with [[TheHero somebody else]], but at the end of the episode, Simon Templar escaped and a heart attack forced the man to enter his machine in emergency.

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* Semi-averted in an episode of ''Series/TheSaint'', where a man with a heart condition wanted to use cryogenics until open heart surgery was commonplace. He did several animal testing, tests, and ''wanted'' to start human testing with [[TheHero somebody else]], but at the end of the episode, Simon Templar escaped and a heart attack forced the man to enter his machine in emergency.



* WhateleyUniverse: A recurring problem with the devisers and gadgeteers of [[SuperheroSchool Whateley Academy]]. Hazmat was lucky; all his treatment did was burn all his hair off his head. Compiler wasn't quite so fortunate - while she did manage to become a faux-Exemplar and speedster through her nanite treatment, she ended up locked in her dorm room most of the time, because she couldn't control her new powers. As for [[BodyHorror Migraine]]... well, she should have known better than to mix two ''different'' devisor projects when she wasn't even a Devisor herself. Then there are the MadScientist types like Jobe, who uses other students as his guinea pigs. Sometimes he even tells them this ahead of time. Sometimes.

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* WhateleyUniverse: Literature/WhateleyUniverse: A recurring problem with the devisers and gadgeteers of [[SuperheroSchool Whateley Academy]]. Hazmat was lucky; all his treatment did was burn all his hair off his head. Compiler wasn't quite so fortunate - while she did manage to become a faux-Exemplar and speedster through her nanite treatment, she ended up locked in her dorm room most of the time, because she couldn't control her new powers. As for [[BodyHorror Migraine]]... well, she should have known better than to mix two ''different'' devisor projects when she wasn't even a Devisor herself. Then there are the MadScientist types like Jobe, who uses other students as his guinea pigs. Sometimes he even tells them this ahead of time. Sometimes.
30th May '16 4:41:34 PM Jacob175
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* Shirogane Ryou of ''TokyoMewMew'', upon completing his father's research, promptly tested it on himself. Because he conveniently didn't have the right genetic code, he did not, in fact, become a magical girl... er, boy.

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* Shirogane Ryou of ''TokyoMewMew'', ''Manga/TokyoMewMew'', upon completing his father's research, promptly tested it on himself. Because he conveniently didn't have the right genetic code, he did not, in fact, become a magical girl... er, boy.



* Averted in ''FrankenFran'': the eponymous character doesn't test a treatment she developed for aging on herself because, as she herself puts it, "It's just too scary~". [[spoiler: For good reason: she based it on telomerase...and cells that have too much of it turn cancerous. Her client, who ordered her killed so she could keep all the research to herself, ends up testing it by self injection...[[LaserGuidedKarma and is]] [[BodyHorror ultimately turned]] [[FateWorseThanDeath into a huge cancerous blob]].]]

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* Averted in ''FrankenFran'': ''Manga/FrankenFran'': the eponymous character doesn't test a treatment she developed for aging on herself because, as she herself puts it, "It's just too scary~". [[spoiler: For good reason: she based it on telomerase...and cells that have too much of it turn cancerous. Her client, who ordered her killed so she could keep all the research to herself, ends up testing it by self injection...[[LaserGuidedKarma and is]] [[BodyHorror ultimately turned]] [[FateWorseThanDeath into a huge cancerous blob]].]]



* In ''Film/TheStoryOfLouisPasteur'', Charbonnet the skeptic injects himself with Pasteur's rabies culture to prove that Pasteur's theories about germs causing disease are wrong. Charbonnet is triumphant when he never gets sick, but this leads Pasteur to a EurekaMoment in which he figures out that weakenened forms of the germ (the sample was three weeks old) can be used in vaccines to combat illness.

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* In ''Film/TheStoryOfLouisPasteur'', Charbonnet the skeptic injects himself with Pasteur's rabies culture to prove that Pasteur's theories about germs causing disease are wrong. Charbonnet is triumphant when he never gets sick, but this leads Pasteur to a EurekaMoment in which he figures out that weakenened weakened forms of the germ (the sample was three weeks old) can be used in vaccines to combat illness.



** In ''TheTimeMachine'' he at least has the presence of mind to build a proof of concept device first.

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** In ''TheTimeMachine'' ''Literature/TheTimeMachine'' he at least has the presence of mind to build a proof of concept device first.



* ''Literature/HarryPotter'': Fred and George test sweets they've made that will cause sudden minor illnesses, allowing you to get out of class, on themselves. After they tried out the Nosebleed Nougat, their mother thought they'd had a fight. The worst is gets, though, is painful boils in an area they "don't normally expose to the public", and even that's eventually fixed. They try to test the sweets out on their fellow students (namely, first-years who wouldn't know to be suspicious), but Hermione stops them by [[DontTellMama threatening to tell their mother about it]].

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* ''Literature/HarryPotter'': Fred and George test sweets they've made that will cause sudden minor illnesses, allowing you to get out of class, on themselves. After they tried out the Nosebleed Nougat, their mother thought they'd had a fight. The worst is it gets, though, is painful boils in an area they "don't normally expose to the public", and even that's eventually fixed. They try to test the sweets out on their fellow students (namely, first-years who wouldn't know to be suspicious), but Hermione stops them by [[DontTellMama threatening to tell their mother about it]].



** And in ''StarTrekFirstContact'', Zefram Cochrane, the inventor of warp drive, flies the test ship himself. Given the post-apocalyptic setting, however, finding a trained pilot may have been very difficult, and it makes a certain amount of sense for the person who ''knows'' the ship inside and out to be aboard. At least he had two astronauts from the future to help out.

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** And in ''StarTrekFirstContact'', ''Film/StarTrekFirstContact'', Zefram Cochrane, the inventor of warp drive, flies the test ship himself. Given the post-apocalyptic setting, however, finding a trained pilot may have been very difficult, and it makes a certain amount of sense for the person who ''knows'' the ship inside and out to be aboard. At least he had two astronauts from the future to help out.



** Averted in ''TheIncredibleHulk'' (2008 film) where Bruce is trying to find a cure and tests it on a blood sample instead of drinking it himself.

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** Averted in ''TheIncredibleHulk'' ''Film/TheIncredibleHulk'' (2008 film) where Bruce is trying to find a cure and tests it on a blood sample instead of drinking it himself.



* The ''Series/MythBusters'' often use themselves as test subjects for their experiements. That said, the experiments they run in this manner have to be approved by their insurance company in advance, and there's always someone keeping tabs on the test subject(s) (if not another one of the hosts, then a producer or other member of the production team), avoiding at least some of the pitfalls of this trope.

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* The ''Series/MythBusters'' often use themselves as test subjects for their experiements.experiments. That said, the experiments they run in this manner have to be approved by their insurance company in advance, and there's always someone keeping tabs on the test subject(s) (if not another one of the hosts, then a producer or other member of the production team), avoiding at least some of the pitfalls of this trope.



* In the ''VideoGame/AnotherCode'' games, Richard ends up having the Another machine tested on himself [[spoiler:twice. And both times, it was done involuntarily by the villains.]]



* In ''WebComic/TheAdventuresOfDrMcNinja'' Dr. Birding tested his formula to transform into a super strong giant on himself, with dubious success. While it does accomplish this, it doesn't cure his paralysis, as was presumably the purpose behind the experiment.

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* In ''WebComic/TheAdventuresOfDrMcNinja'' Dr. Birding tested his formula to transform into a super strong giant on himself, with dubious success. While it does accomplish this, it doesn't cure his paralysis, as which was presumably the purpose behind the experiment.



* Giles Brindley, inventor of [[http://alignmap.com/2006/11/06/presentation-is-not-really-everything-the-giles-brindley-show/ early drug treatments]] for impotence. Link may be NSFW.[[note]]No, not like [[{{Fanservice}} that]].[[/note]] Link may also be [[GroinAttack disturbing to male readers]].

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* Giles Brindley, inventor of [[http://alignmap.com/2006/11/06/presentation-is-not-really-everything-the-giles-brindley-show/ early drug treatments]] for impotence. Link may be NSFW.[[note]]No, not like [[{{Fanservice}} that]].[[/note]] Link may also be [[GroinAttack [[ShareTheMalePain disturbing to male readers]].
15th May '16 5:03:59 PM Sharlee
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* Naturalist Farley Mowat, endeavoring to prove that Arctic wolves weren't to blame for declining caribou numbers in subarctic Canada, noted that the animals he was studying were living exclusively on rodents for most of the year. To confirm that such a large animal could survive on tiny prey, he proceeded to [[ReducedToRatburgers catch and eat nothing but rodents]] for protein himself.

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* Naturalist Farley Mowat, endeavoring to prove that Arctic wolves weren't to blame for declining caribou numbers in subarctic Canada, noted that the animals wolf family he was studying were living exclusively on rodents for most of the year. To confirm that such a large animal could survive on tiny prey, he proceeded to [[ReducedToRatburgers catch and eat nothing but rodents]] for protein himself.
15th May '16 5:03:22 PM Sharlee
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Added DiffLines:

* Naturalist Farley Mowat, endeavoring to prove that Arctic wolves weren't to blame for declining caribou numbers in subarctic Canada, noted that the animals he was studying were living exclusively on rodents for most of the year. To confirm that such a large animal could survive on tiny prey, he proceeded to [[ReducedToRatburgers catch and eat nothing but rodents]] for protein himself.
7th May '16 8:37:53 PM Theriocephalus
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[[folder:Tabletop RPG]]

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[[folder:Tabletop RPG]]Games]]
2nd Mar '16 8:24:05 AM DarkPhoenix94
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Added DiffLines:

* Bruce Banner supposedly did this in ''Fanfic/ChildOfTheStorm'', having seen the files on [[PlayingWithSyringes Camp Cathcart.]] The result was the Hulk.
** [[spoiler: Sinister]] got his powers this way.
2nd Dec '15 4:29:18 AM Morgenthaler
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* One that crosses it with RealLife was ''SuperSizeMe'' where the filmmaker ate nothing but [=McDonalds=] for a month and had the results filmed and monitored.

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* One that crosses it with RealLife was ''SuperSizeMe'' ''Film/SuperSizeMe'' where the filmmaker ate nothing but [=McDonalds=] for a month and had the results filmed and monitored.
20th Nov '15 12:08:10 AM Xelloss08
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** The same thing happens in the LovecraftLite story ''The Wreck of the Charles Dexter Ward'' by Elizabeth Bear and Creator/SarahMonette.

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** The same thing happens in * In the LovecraftLite Literature/{{Boojumverse}} story ''The "The Wreck of the Charles ''Charles Dexter Ward'' Ward''" by Elizabeth Bear and Creator/SarahMonette.Creator/SarahMonette, the villain injects herself with her experimental reanimation serum, believing that receiving it while still alive will produce better results than the mostly mindless zombies created by her previous tests.
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