History Main / JekyllAndHyde

* ''AceLightning'' has Random Virus, who has two personalities, good and evil, signified by his cyborg eye being green or red, respectively. He doesn't seem to have much control over whether he's good or evil, although Ace managed to turn him good temporarily by reminding him that he was a Lightning Knight, and therefore a 'good guy'.

* ''TheVampireDiaries'': Stefan Salvatore. He has one side of his personality which is kind, caring, empathetic and compassionate and heroic ("Jekyll", Hero!Stefan) and another side of his personality which is sociopathic, crazy, addictive, cold and ruthless ("Hyde", Ripper!Stefan)

* On ''TheBigBangTheory'', after Penny wakes up with Raj, she refers to herself as Dr. Jekyll and Miss Whore.

* Every character in ''TabletopGame/KindredOfTheEast'': the soul of an eastern vampire is divided into the higher Hun and the lower P'o. It is as troublesome as it sounds, but the P'o is indispensible. It serves as the SuperpoweredEvilSide, providing some essential combat powers (indeed, a vampire couldn't even grow fangs without it) and is responsible for him being undead in the first place (via LikeABadassOutOfHell).

The infamous Zodiac killer claimed this in one of his letters.He said that he would "lose all control" to his Zodiac persona soon,and set up a bomb to blow up children.However,this may been just a trick to humilate the police once again.

* Angel Starr from the first ''VisualNovel/PhoenixWrightAceAttorney'' game, complete with PeekABangs moving from one eye to another depending on whether she's sweet or sour.

** The exact same situation with TheSentry and The Void at Marvel.

* ''TabletopGame/MeMyselfAndIrene'' had this with Jim Carrey playing two guys in one- nice cop Charlie and bad cop Hank.
* ''RepoTheGeneticOpera'' has Nathan, doting father by day, [[PsychoForHire Repo Man]] by night.

* Julius Kelp (Sherman Klump in the remake) and Buddy Love in ''TheNuttyProfessor''.

* In ''CitizenKane'', Charles Foster Kane tells Thatcher early on, "The trouble is, you don't realize that you're talking to two people," referring to himself as both a man of wealth and as a man of the people. One of the main points of the movie is the internal war between those two sides. [[spoiler: It can be argued that both sides lose by the end of the movie.]]

** Eh... Somewhat. Nathan's seems to be a more intentional shifting between identities rather than a real split personality. This can be seen during the scene where he's talking to Shilo as Nathan while performing his job as Repo Man at the same time.
*** Zdunich has referred to the character(s) as "Doctor Nathan and Mr. Repo Man", so Word Of God... er... at least considers that reference accurate?

* Kenshin and Battousai in ''RurouniKenshin.''

* ''MagicalProjectS'': Misao Amano's normal self is that of a stereotypical ShrinkingViolet [[FriendlessBackground friendless]], [[ShyBlueHairedGirl blue-haired]] IllGirl. However, this persona falls away when she's transformed into Pixy Misa, the manifestation of her deeply repressed id: an egomaniacal [[GreenEyedMonster jealous]] DarkMagicalGirl [[VillainousHarlequin trickster]].

Jekyll's transformation is inverted and averted by Julian Advent of the ''{{Nightside}}'' series, who faced the same choice as Jekyll when he discovered a similar formula, but chose to drink the version that brought his ''Good'' side to the fore, making him TheCape instead of this trope.

* ''ScoobyDooWhereAreYou'': "Nowhere To Hyde" (season 2, episode 1) mixes this with the standard ScoobyDooHoax. A diamond necklace is stolen by a figure people see is the Ghost of Hyde. The gang (after circumstances from confronting Hyde) follow him to a house in the woods where they meet Dr. Jekyll, who says he's the ghost of Hyde after attempting to mix and test a vitamin formula. The standard c=investigations and chases ensue and after Hyde is captured, it turns out the Hyde ''was'' Dr. Jekyll in a mask who tried to frame his housekeeper for the crime.

** ''ComicBook/BatmanTheDarkKnightReturns'' turns this on its head. [[spoiler: Recent breakthroughs in plastic surgery have restored his face to normal, but at the unforseen cost of forever destroying the "Harvey" half of his personality, and permanently leaving the "Face" in complete control.]]
* The Green Goblin is sometimes, and to an extent originally, depicted as a split personality of the milquetoast scientist NormanOsborn in ''SpiderMan''. The main difference is that Osborn is a ManipulativeBastard, while the Goblin is a AxCrazy psychopath. Since he came BackFromTheDead, Osborn had been more or less in control and became the Goblin willingly and [[ForTheEvulz for shitz and giggles]], but recently he's started losing it again.

* [[{{Smallville}} Davis Bloome]]/Doomsday.

* Adam Worth from {{Sanctuary}} is said to be the in-universe explanation for the novel. Neither personality is particularly stronger, but unlike most examples, both sides work in tandem.

** ''TheDarkKnightReturns'' turns this on its head. [[spoiler: Recent breakthroughs in plastic surgery have restored his face to normal, but at the unforseen cost of forever destroying the "Harvey" half of his personality, and permanently leaving the "Face" in complete control.]]