History Main / IntoxicatedSuperpowerSnag

* ''Film/Lifechanger'': Drew's ability to maintain his form falters when he takes cocaine, resulting in the usual PowerDegeneration and physical decomposition setting in much earlier. However, Drew's ability to steal new forms work better the closer he is to decomposing, so he's careful to keep a little cocaine on hand just in case he needs a quick change of appearance.
* ''Film/MinorityReport'': Combined with JunkieProphet. The Precogs' ability to predict murders days before they happen only works [[DreamingOfThingsToCome in their nightmares]], so the Department of Precrime keeps Agatha, Arthur, and Dashiel drugged so that they'll always be receptive to new visions... at the cost of leaving them [[AndIMustScream stuck endlessly watching murders and unable to wake from their semi-conscious dream-states]]. After Agatha is freed by Anderton, it's discovered that she still has powers while sober and awake, though her conscious vision is limited to a few minutes into the future—meaning that she's been operating under this trope for most of her life.

[[/folder]]

-->-- '''Agent X,''' ''VideoGame/TheShapeshiftingDetective''

[[folder: Comic Books]]

* ''ComicBook/SupermanBatman'': During "The Search for Kryptonite" arc, Silver Kryptonite makes Superman hallucinate, gives him the munchies, and enhances his superhuman senses to the point where he can smell someone baking brownies in North Dakota... while on the Watchtower, ''which is in orbit around the Earth.''

[[folder: Fanfic]]

* In the ''WesternAnimation/TeenTitans'' fic ''[[https://www.fanfiction.net/s/9809658/1/Tremble-Mortal Tremble Mortal]]'', Aqualad comes to Raven's room and offers her a bit of liquor. It turns out that any alcohol both makes her lose access to her powers and effectively paralyzes her. Almost leads to some unpleasant consequences when Aqualad gets a bit touchy and mistakes her lack of objection for consent, but she manages to break through before it gets too far.

[[folder: Film — Live Action]]
* ''Film/MinorityReport:'' Combined with JunkieProphet. The Precogs' ability to predict murders days before they happen only works [[DreamingOfThingsToCome in their nightmares]], so the Department of Precrime keeps Agatha, Arthur, and Dashiel drugged so that they'll always be receptive to new visions... at the cost of leaving them [[AndIMustScream stuck endlessly watching murders and unable to wake from their semi-conscious dream-states]]. After Agatha is freed by Anderton, it's discovered that she still has powers while sober and awake, though her conscious vision is limited to a few minutes into the future—meaning that she's been operating under this trope for most of her life.
* ''Film/{{Scanners}}:'' A mild tranquilizer known as Ephemerol is the one thing that can temporarily disable a Scanner's PsychicPowers. As such, Cameron Vale uses it to blot out the voices that torment him, while [[MegaCorp ConSec]] makes sure to keep some on hand in case unfriendly Scanners come knocking. It's eventually revealed that Ephemerol's effects aren't just due to its nature as a tranquilizer: [[spoiler: it's actually responsible for the BizarreBabyBoom that created Scanners in the first place.]]

[[folder: Literature]]
* ''Literature/{{Animorphs}}:'' In "[[Recap/AnimorphsTheUnderground The Underground]]," it's discovered that the [[PuppeteerParasite Yeerks]] are chemically susceptible to maple-and-ginger flavored instant oatmeal, which they treat as [[AlienCatnip a highly addictive drug]] on par with crystal meth. Furthermore, the negative side-effects also result in afflicted Yeerks intermittently losing control of their hosts during their demented frenzies, hence how the Animorphs found out about this in the first place.

[[folder: Live-Action TV]]

* ''Series/JessicaJones2015'': In "[[Recap/JessicaJones2015S1E2AKACrushSyndrome AKA Crush Syndrome]]," Jessica learns that [[BigBad Kilgrave]] had to have a kidney transplant after being hit by a bus and [[SkipTheAnesthetic insisted on remaining conscious throughout the operation]]. From this, she realizes that Kilgrave can't maintain the use of [[CompellingVoice his powers]] while under the influence of surgical anesthesia, which would shut down the parts of his brain responsible for controlling his slaves. In the episodes that follow, Jessica sets out to obtain drugs in order to safely capture him, and in "[[Recap/JessicaJones2015S1E5AKATheSandwichSavedMe AKA The Sandwich Saved Me]]," she and Simpson are able to successfully abduct Kilgrave without any brainwashed pawns interfering. [[spoiler: Unfortunately, Kilgrave [[ProperlyParanoid planned ahead]] by legitimately hiring a group of mercenaries to guard him, so their allegiance doesn't change while his powers are on the fritz. Consequently, he's rescued almost immediately, allowing him to recover the use of his powers in private.]]

** After suffering a HeroicBSOD in "[[Recap/TheUmbrellaAcademy2019S01E07 The Day That Wasn't]]," Luther gets drunk, goes clubbing, and does a shitload of party drugs as well. Klaus, jittery from withdrawal, fears that being high will have similar nullifying effects on Luther's super-strength and is forced to go to the rescue when his brother's drugged-up antics end up pissing off some local tough guys.
** It's eventually revealed that [[spoiler: Viktor AKA Number 7 actually has superpowers, but after realizing how dangerous they were, Reginald Hargreeves [[NightmareOfNormality erased Viktor's memory of them with help from Alison]]. Since then, Viktor has been prescribed anti-anxiety medication in order to suppress his abilities, and given his chronic lack of confidence, he isn't inclined to stop taking them. The plot naturally begins heating up when Leonard Peabody steals Viktor's prescription, gradually allowing his powers to return... but after spending most of his life having his emotions suppressed by drugs, Viktor has [[MoodSwinger no gauge on his emotions]] - and consequently, not much restraint in the use of his powers.]]

[[folder: Video Games]]
* ''VideoGame/BioShock:'' Both [[VideoGame/BioShock1 Jack]] and [[VideoGame/BioShock2 Subject Delta]] find that alcohol drains their EVE bars, leaving them with progressively less energy to use on plasmids... but on the upside, [[BoozeBasedBuff alcohol restores their health bars]], so it's useful if you don't have any health kits and don't mind squandering mana. By contrast, nicotine regenerates the player characters' EVE bars but damages their health bars.
* ''VideoGame/TheShapeshiftingDetective:'' If you decide to become Lexie and try to get answers out of Zak Weston, he immediately gets ''very'' sleazy, offering you a glass of vodka as he tries to rope you into [[SleazyPhotoshoot a naked photoshoot]]. If you actually go through with it, you quickly discover that [[SlippingAMickey your drink has been spiked]], causing you to lose control of your powers and [[ARottenTimeToRevert revert to your true form]]—not the "Sam" persona, but your ''real'' true form. You recover quickly, but Zak is so horrified by the sight that he refuses to speak to you again.

[[folder: Webcomics]]

[[folder: Western Animation]]
* ''WesternAnimation/RickAndMorty:'' In "[[Recap/RickAndMortyS2E3AutoEroticAssimilation Auto Erotic Assimilation]]", Rick bumps into an OldFlame by the name of Unity, a planet-spanning HiveMind that's assimilated the local population and can control them in any way it pleases. Unfortunately, it's not long before the two of them renew their relationship and start doing drugs again... and as a result of its intoxication, Unity loses control of a few thousand host bodies. Worse still, it turns out that the planet's population was in the middle of a race war when [[TheExtremistWasRight Unity took control of them]], and the conflict starts up again within minutes of the hosts being freed. Plus, one of the sex offenders that Unity had reformed [[AttemptedRape goes after Summer]], though Unity is able to rescue her and Morty before things get any worse. [[spoiler: Ultimately, Rick's bad influence proves to be one of the major reasons why Unity decides that it can't be with him anymore, prompting it and its host bodies to leave the planet with only a series of {{Dear John Letter}}s in their wake.]]

->''Don't get drugged. You'll revert to your natural form. ''Nobody'' wants to see that.''

-->--'''Agent X,''' ''VideoGame/TheShapeshiftingDetective''

Not everyone reacts to intoxication the same way. In both fiction and reality, many people have experienced unusual reactions to drugs, not because of a dodgy product or FantasticDrug, but simply because the users are slightly different to the usual market—to the point that some cocaine users can actually fall asleep while high.

However, the most unusual responses appear in wielders of fantastic powers: mutants, mages, superhumans, shapeshifters, and a huge variety of other beings blessed with otherworldly powers experience drastic side-effects as a result of getting high, most commonly affecting their powers and how they work—or ''don't'' work.

Compare MalfunctionMalady, in which illnesses has similar effects on superpowered entities.

Contrast AddictionPowered and JunkieProphet, in which the drugs actually ''induce'' the abilities, and and NeverGetsDrunk, in which the superpowers make it impossible for drugs to affect the wielder ''at all.''

* In the ''WesternAnimation/TeenTitans'' fic ''[[https://www.fanfiction.net/s/9809658/1/Tremble-Mortal Tremble Mortal]]'', Aqualad comes to Raven's room and offers her a bit of liquor. It turns out that any alcohol both makes her lose access her powers and effectively paralyzes her. Almost leads to some unpleasant consequences when Aqualad gets a bit touchy and mistakes her lack of objection for consent, but she manages to break through before it gets too far.

* ''Literature/RiversOfLondon'': Implied. [[PunchClockVillain Varvara Sidorovna Tamonina]] relates that during her wild times in the 1970's, she once tried to do magic whilst high on acid. Exactly what happens is never explained, but she definitely recommends her audience not to try it for themselves.

* ''Series/HikoninSentaiAkibaranger'': In Episode 3, the team discovers that being drunk intensifies the Akibarangers' powers within the Delusion World. Moegi (who's a Fujoshi) decides to try this out as well during the next bout, causing the MonsterOfTheWeek to constantly shift between a bad-ass supervillain and a Yaoi protagonist, putting Red and Yellow at-odds and making the fight a lot harder than it needs to be. Akiba Blue ends up being the one to saves the day by quoting ''Series/GoGoSentaiBoukenger,'' sobering the other two up.
* ''Series/JessicaJones2015'': In "[[Recap/JessicaJones2015S1E2AKACrushSyndrome AKA Crush Syndrome]]," Jessica learns that [[BigBad Kilgrave]] had to have a kidney transplant after being hit by a bus and [[SkipTheAnesthetic insisted on remaining conscious throughout the operation]]. From this, she realizes that Kilgrave can't maintain the use of [[CompellingVoice his powers]] while under the influence of surgical anaesthesia, which would shut down the parts of his brain responsible for controlling his slaves. In the episodes that follow, Jessica sets out to obtain drug in order to safety capture him, and in "[[Recap/JessicaJones2015S1E5AKATheSandwichSavedMe AKA The Sandwich Saved Me]]," she and Simpson are able to successfully abduct Kilgrave without any brainwashed pawns interfering. [[spoiler: Unfortunately, Kilgrave [[ProperlyParanoid planned ahead]] by legitimately hiring a group of mercenaries to guard him, so their allegiance doesn't change while his powers are on the fritz. Consequently, he's rescued almost immediately, allowing him to recover the use of his powers in private.]]

* ''Webcomic/DominicDeegan'' was once the victim of a cruel prank as a kid involving a variation of this trope, recounted [[https://www.dominic-deegan.com/comic/2602-20110113/ here]]. One of his classmates had recently had Alterism (the local magical equivalent of plastic surgery) done to fix his cleft lip, and Dominic was dared to use his Second Sight to watch the procedure. What Dominic didn't know is the classmate had taken a hallucinogen that affects seers. Instead of seeing the worst parts of the procedure (which is what everyone expected), for a week, he had horrible nightmare visions of everything that can go wrong with Alterism. And thanks to the drug distorting his visions, he was the subject every time. Understandably, he's not a big fan of that magic.

Not everyone reacts to intoxication the same way. In both fiction and reality, many people have experienced unusual reactions to drugs, not because of a dodgy product or FantasticDrug, but simply because the users are slightly different to the usual market - to the point that some cocaine users can actually fall asleep while high.

However, the most unusual responses appear in wielders of fantastic powers: mutants, mages, superhumans, shapeshifters, and a huge variety of other beings blessed with otherworldly powers experience drastic side-effects as a result of getting high, most commonly affecting their powers and how they work - or ''don't'' work.

In the case of psychics and other superhumans with abilities dependent on focus and willpower, this is due to the drug eroding their ability to concentrate, reducing the effectiveness of their powers or even leaving the character BroughtDownToNormal until they've sobered up. In other cases, however, it's due to the chemical itself interacting with the power in unexpected ways, allowing for weirder and potentially more dangerous effects - including everything from a change of powers to a full-blown SuperpowerMeltdown.

* ''Fanfic/DungeonKeeperAmi'': Combined with DrunkenMaster. When Ami was drunk, she managed to reconfigure a spell to change the shape of its effect - but can't figure out how to do it while sober.

* ''Film/MinorityReport:'' Combined with JunkieProphet. The Precogs' ability to predict murders days before they happen only works [[DreamingOfThingsToCome in their nightmares]], so the Department of Precrime keeps Agatha, Arthur, and Dashiel drugged so that they'll always be receptive to new visions... at the cost of leaving them [[AndIMustScream stuck endlessly watching murders and unable to wake from their semi-conscious dream-states]]. After Agatha is freed by Anderton, it's discovered that she still has powers while sober and awake, though her conscious vision is limited to a few minutes into the future - meaning that she's been operating under this trope for most of her life.

* ''VideoGame/TheShapeshiftingDetective:'' If you decide to become Lexie and try to get answers out of Zak Weston, he immediately gets ''very'' sleazy, offering you a glass of vodka as he tries to rope you into [[SleazyPhotoshoot a naked photoshoot]]. If you actually go through with it, you quickly discover that [[SlippingAMickey your drink has been spiked]], causing you to lose control of your powers and [[ARottenTimeToRevert revert to your true form]] - not the "Sam" persona, but your ''real'' true form. You recover quickly, but Zak is so horrified by the sight that he refuses to speak to you again.

[[folder: Film - Live Action]]

[[folder: Live Action TV]]