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* "Tsst"'s ending becomes a lot harder to watch when find out what happens to Cartman in his adulthood: [[spoiler: In "Return of COVID", after Bad Future!Cartman sacrifices his current life to save his friends from being cynical and miserable, Good Future!Cartman is revealed to be a homeless shell of his former self, abusing alcohol and shouting obscenities on the street.]] Cesar helped ''avert'' that future for him only for Liane to selfishly revert Cartman back to his original self, putting him back on the path towards his bleak adulthood, all because [[ForWantOfANail Cesar rejected Liane's advances.]]
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* "Tsst"'s ending becomes a lot harder to watch when find out what happens to Cartman in his adulthood: [[spoiler: In "Return of COVID", after Bad Future!Cartman sacrifices his current life to save his friends from being cynical and miserable, Good Future!Cartman is revealed to be a homeless shell of his former self, abusing alcohol and shouting obscenities on the street.]] Cesar helped ''avert'' that future for him only for Liane to selfishly revert Cartman back to his original self, putting him back on the path towards his bleak adulthood, all because [[ForWantOfANail Cesar rejected Liane's advances.]]
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** Also from the same episode, a scene was cut by executives before broadcasts out of fear of any real-life imitations, depicting Shelley repeatedly setting Stan on fire before throwing water over him. 24 years later, in ''WesternAnimation/SouthParkPostCovid'', [[spoiler: it's revealed that, in the BadFuture, Stan unintentionally burned Shelley to death when he set fire to Tegridy Farms.]]
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** Also from the same episode, a scene was cut by executives before broadcasts out of fear of any real-life imitations, depicting Shelley repeatedly setting Stan on fire before throwing water over him. 24 years later, in ''WesternAnimation/SouthParkPostCovid'', [[spoiler: it's revealed that, in the BadFuture, Stan [[LaserGuidedKarma unintentionally burned Shelley to death death]] when he set fire to Tegridy Farms.]]
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** Also from the same episode, a scene was cut by executives before broadcasts out of fear of any real-life imitations, depicting Shelley repeatedly setting Stan on fire before throwing water over him. 24 years later, in ''WesternAnimation/SouthParkPostCovid'', [[spoiler: its revealed that, in the BadFuture, Stan unintentionally burned Shelley to death when he set fire to Tegridy Farms.]]
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** Also from the same episode, a scene was cut by executives before broadcasts out of fear of any real-life imitations, depicting Shelley repeatedly setting Stan on fire before throwing water over him. 24 years later, in ''WesternAnimation/SouthParkPostCovid'', [[spoiler: its it's revealed that, in the BadFuture, Stan unintentionally burned Shelley to death when he set fire to Tegridy Farms.]]
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* More of a "Heartwarming Aneurysm Moment", but remember all of those adorable scenes in Season 20 focusing on the blooming romance between Cartman and Heidi, and how dedicated he was to her? Try watching them after "[[Recap/SouthParkS21E6SonsAWitches Sons a Witches]]" or "[[Recap/SouthParkS21E7DoublingDown Doubling Down]]", when we see just how badly the relationship has fallen apart, especially as he gets worse every episode.
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* More of a "Heartwarming Aneurysm Moment", in Hindsight", but remember all of those adorable scenes in Season 20 focusing on the blooming romance between Cartman and Heidi, and how dedicated he was to her? Try watching them after "[[Recap/SouthParkS21E6SonsAWitches Sons a Witches]]" or "[[Recap/SouthParkS21E7DoublingDown Doubling Down]]", when we see just how badly the relationship has fallen apart, especially as he gets worse every episode.
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* The fourth season episode "[[Recap/SouthParkS4E8SomethingYouCanDoWithYourFinger Something You Can Do With Your Finger]]" has a joke about the girls of South Park saying that they would be much more excited about meeting Matt Lauer than the new boy band that the boys are trying to start. The aneurysm then occurred in 2017 when Lauer was fired from his position at NBC due to his long history of sexual harassment towards his female coworkers. More concerning is the girls' mouth animations make their screams look more frightened than excited, and the screaming also sounded like they were horrified, too.
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* The fourth season episode "[[Recap/SouthParkS4E8SomethingYouCanDoWithYourFinger Something You Can Do With Your Finger]]" has a joke about the girls of South Park saying that they would be much more excited about meeting Matt Lauer than the new boy band that the boys are trying to start. The aneurysm then occurred Then in 2017 when 2017, Lauer was fired from his position at NBC due to his long history of sexual harassment towards his female coworkers. More concerning is the girls' mouth animations make their screams look more frightened than excited, and the screaming also sounded like they were horrified, too.
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-->'''Subway Rep:''' Mr. Jared's views do not necessarily reflect the views of the Subway company.
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-->'''Subway Rep:''' The opinions expressed by Mr. Jared's views do Fogle are not necessarily reflect the views those of the Subway company.
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** Also from the same episode, a scene was cut by executives before broadcasts out of fear of any real-life imitations, depicting Shelley repeatedly setting Stan on fire before throwing water over him. 24 years later, in ''WesternAnimation/SouthParkPostCovid'', [[spoiler: its revealed that, in the BadFuture, Stan unintentionally burned Shelley to death when he set fire to Tegridy Farms.]]
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* In "[[Recap/SouthParkS4E12TrapperKeeper Trapper Keeper]]", a man under the alias Bill Cosby comes to South Park pretends to want to be Cartman's friend. And Cartman responds "Nah, my mom says I'm not allowed to have male friends over thirty." This line becomes a lot less funny after the rape allegations against Creator/BillCosby.[[note]]Although it could also be a CallBack to the events of "Cartman Joins NAMBLA".[[/note]]
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* In "[[Recap/SouthParkS4E12TrapperKeeper Trapper Keeper]]", a man under the alias Bill Cosby comes to South Park pretends to want to be Cartman's friend. And Cartman responds "Nah, my mom says I'm not allowed to have male friends over thirty." This line becomes a lot less funny after the rape allegations against and eventual imprisonment of the real Creator/BillCosby.[[note]]Although it could also be a CallBack to the events of "Cartman Joins NAMBLA".[[/note]]
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* A RunningGag from the show's early days was Mr. Garrison asking the mayor if they can "kill all the Mexicans". Decades later, Mr. Garrison would become a {{parody}} of UsefulNotes/DonaldTrump, and one of the most horrific things to come out of the Trump Administration would be [[https://en.wikipedia.org/wiki/Trump_administration_family_separation_policy the displacement and detainment of countless Mexican children in inhumane internment camps at the US / Mexico border.]] It became even less funny in 2019 after a white supremacist carried out a mass shooting in El Paso, Texas with the explicit goal of killing Latinos. The anti-Mexican racism of the administration's internment camps would later be tackled in the Season 23 premiere.
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* A RunningGag from the show's early days was Mr. Garrison asking the mayor if they can "kill all the Mexicans". Decades later, Mr. Garrison would become a {{parody}} of UsefulNotes/DonaldTrump, and one of the most horrific things to come out of the Trump Administration would be [[https://en.wikipedia.org/wiki/Trump_administration_family_separation_policy the displacement and detainment of countless Mexican children in inhumane internment camps at the US / Mexico border.]] It became even less funny in 2019 after a white supremacist carried out a mass shooting in at El Paso, Texas with the explicit goal of killing Latinos. The anti-Mexican racism of the administration's internment camps would later be tackled in the Season 23 premiere.
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* A RunningGag from the show's early days was Mr. Garrison asking the mayor if they can "kill all the Mexicans". Decades later, Mr. Garrison would become a {{parody}} of UsefulNotes/DonaldTrump, and one of the most horrific things to come out of the Trump Administration would be [[https://en.wikipedia.org/wiki/Trump_administration_family_separation_policy the displacement and detainment of countless Mexican children in inhumane internment camps at the US / Mexico border.]] and it's considered less funny after a mass shooting in El Paso, Texas on June 4th, 2019 in which 22 people were killed in an act of domestic terrorism. The shooter, Patrick Crusius, stated that "he was out to kill as many Mexicans as he could." The anti-Mexican racism of the administration's internment camps would later be tackled in the Season 23 premiere.
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* A RunningGag from the show's early days was Mr. Garrison asking the mayor if they can "kill all the Mexicans". Decades later, Mr. Garrison would become a {{parody}} of UsefulNotes/DonaldTrump, and one of the most horrific things to come out of the Trump Administration would be [[https://en.wikipedia.org/wiki/Trump_administration_family_separation_policy the displacement and detainment of countless Mexican children in inhumane internment camps at the US / Mexico border.]] and it's considered It became even less funny in 2019 after a white supremacist carried out a mass shooting in El Paso, Texas on June 4th, 2019 in which 22 people were killed in an act with the explicit goal of domestic terrorism. The shooter, Patrick Crusius, stated that "he was out to kill as many Mexicans as he could." killing Latinos. The anti-Mexican racism of the administration's internment camps would later be tackled in the Season 23 premiere.
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* On the subject of "The Return of COVID", Cartman's [[CrazyHomelessPerson awful fate]] at the end of the special puts several previous episodes in a more negative light:
** After getting kicked out of the group in "Bebe's Boobs Destroy Society", Cartman flips off Stan and Kyle (and Tweek) and shouts "Fuck you!" to each of them. In this episode, it was Played for Laughs. When something similar happens in "The Return of COVID" it's not played for laughs at all, and hearing a now-friendless Cartman flip the boys off while yelling "Fuck you!" is downright tragic when you take into account the ending of said episode.
** The ending of "My Future Self and Me" has a RidiculouslySuccessfulFutureSelf version of Cartman travel back in time to meet himself in the present in an attempt to ensure that he stays on the path to a good future, only for Cartman to end up becoming a FutureLoser instead due to Cartman thinking his "future self" is just a paid actor, like the other "future self" characters seen earlier in the episode. Let's just say that after the "Return Of COVID" special, Cartman's new future self at the end of ''this'' episode seems successful by comparison, and like this episode, he caused it due to time travel.
** Eric Cartman mocks the homeless throughout one episode, as well as jumping over them with his skateboard and exaggerating his feat, to the point it becomes a hobby of his by the end of the episode. After watching the "Return of COVID" special when Cartman himself becomes homeless, once again, something that was PlayedForLaughs won't be so funny to watch anymore.
** After getting kicked out of the group in "Bebe's Boobs Destroy Society", Cartman flips off Stan and Kyle (and Tweek) and shouts "Fuck you!" to each of them. In this episode, it was Played for Laughs. When something similar happens in "The Return of COVID" it's not played for laughs at all, and hearing a now-friendless Cartman flip the boys off while yelling "Fuck you!" is downright tragic when you take into account the ending of said episode.
** The ending of "My Future Self and Me" has a RidiculouslySuccessfulFutureSelf version of Cartman travel back in time to meet himself in the present in an attempt to ensure that he stays on the path to a good future, only for Cartman to end up becoming a FutureLoser instead due to Cartman thinking his "future self" is just a paid actor, like the other "future self" characters seen earlier in the episode. Let's just say that after the "Return Of COVID" special, Cartman's new future self at the end of ''this'' episode seems successful by comparison, and like this episode, he caused it due to time travel.
** Eric Cartman mocks the homeless throughout one episode, as well as jumping over them with his skateboard and exaggerating his feat, to the point it becomes a hobby of his by the end of the episode. After watching the "Return of COVID" special when Cartman himself becomes homeless, once again, something that was PlayedForLaughs won't be so funny to watch anymore.
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Examples related to a real-life figure's death only count if the death in the work is similar to their death in real life. Removing as discussed on the Hindsight clean-up thread
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* In "The Snuke", the titular bomb in Hilary Clinton's vagina turns out to be part of a plot by England take back the United States, and its thwarting causes Queen Elizabeth II to [[DrivenToSuicide blow her brains out]]. This becomes more uncomfortable in light of the Queen's actual death in September 2022.
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* In "The Snuke", the titular bomb in Hilary Clinton's vagina turns out to be part of a plot by England take back the United States, and its thwarting causes Queen Elizabeth II to [[DrivenToSuicide blow her brains out]]. This becomes more uncomfortable in light of the Queen's actual death in September 2022.
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* In "Return of COVID", [[spoiler: Cartman performs an HeroicSacrifice so his friends can live better lives in the new timeline, at the cost of him being homeless and unemployed, losing his family, and his friends forgetting everything he did for them.]] In ''Film/SpiderManNoWayHome'', released ''a mere day'' after the special, [[spoiler: Peter Parker essentially goes through the same thing at the end of the movie.]]
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* In "Return of COVID", [[spoiler: Cartman performs an HeroicSacrifice so his friends can live better lives in the new timeline, at the cost of him being homeless and unemployed, homeless, losing his family, and his friends forgetting everything he did for them.]] In ''Film/SpiderManNoWayHome'', released ''a mere day'' after the special, [[spoiler: Peter Parker essentially goes through the same thing at the end of the movie.]]
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* In "Return of COVID", [[spoiler: Cartman performs an HeroicSacrifice so his friends can live better lives in the new timeline, at the cost of him being homeless and unemployed, losing his family, and his friends forgetting everything he did for them.]] In ''Film/SpiderManNoWayHome'', released ''a mere day'' after the special, [[spoiler: Peter Parker essentially goes through the same thing at the end of the movie.]]
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* In [[Recap/SouthParkS16E12ANightmareOnFaceTime A Nightmare On Face Time]], Randy is treated like an idiot for wanting to run a movie rental store in the age of streaming. While Netflix ''was'' far more convenient than Blockbuster in 2012, ten years later Netflix is starting to show a noticeable decline in popularity, not helped by the rise of various other competitors which are now necessary to all subscribe to in order to have access to all the content that was on Netflix in 2012. So for those who don't want to pay for Creator/DisneyPlus, Creator/HBOMax, Creator/{{Peacock}}, Creator/ParamountPlus, etc. alongside Netflix, a video rental store might be necessary in TheNewTwenties.
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Example was here twice
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* In an in-universe example of this, the revelation in the WhamEpisode "[[Recap/SouthParkS14E6TwoHundredOne 201]]" completely twists the climax of "[[Recap/SouthParkS5E4ScottTenormanMustDie Scott Tenorman Must Die]]" around in a new light. For those who wonder: [[spoiler:Cartman's true father and Scott Tenorman's father are the same. Meaning that Cartman killed his own dad and thus that his his victory in "Scott Tenorman Must Die" was a retroactive PyrrhicVictory.]]
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* One of the last scenes of "[[Recap/SouthParkS5E14ButtersVeryOwnEpisode Butters' Very Own Episode]]" has Gary Condit, [=JonBenet=] Ramsey's parents, and UsefulNotes/OJSimpson being called out quite viciously and angrily for being murderers who lie through their teeth while playing the victim card. Though it was basically conventional wisdom at the time that Condit and the Ramseys were guilty liars, it has since that it has been confirmed that the Ramseys and Condit were innocent victims who were ConvictedByPublicOpinion, making their call-outs in the episode not ''nearly'' as funny and biting when viewed today. This revelation came too late for Patsy Ramsey, having died of ovarian cancer. [[http://www.nytimes.com/2011/09/25/magazine/talk-trey-parker-and-matt-stone-of-south-park.html?_r=0 Matt Stone and Trey Parker have gone on record saying that they deeply regret this.]]
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* One of the last scenes of "[[Recap/SouthParkS5E14ButtersVeryOwnEpisode Butters' Very Own Episode]]" has Gary Condit, [=JonBenet=] Ramsey's parents, and UsefulNotes/OJSimpson being called out quite viciously and angrily for being murderers who lie through their teeth while playing the victim card. Though it was basically conventional wisdom at the time that Condit and the Ramseys were guilty liars, it has since that it has then been confirmed that that, unlike O.J. Simpson, the Ramseys and Condit were innocent victims who were ConvictedByPublicOpinion, making their call-outs in the episode not ''nearly'' as funny and biting when viewed today. This revelation came too late for Patsy Ramsey, having died of ovarian cancer.cancer five years after the episode premiered. [[http://www.nytimes.com/2011/09/25/magazine/talk-trey-parker-and-matt-stone-of-south-park.html?_r=0 Matt Stone and Trey Parker have gone on record saying that they deeply regret this.]]
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** Naturally, the next times Jared showed up (in Season 19's "[[Recap/SouthParkS19E1StunningAndBrave Stunning and Brave]]" and ''VideoGame/SouthParkTheFracturedButWhole''), his pedophilia ''was'' [[CrossesTheLineTwice the main joke.]]
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** Naturally, the next times Jared showed up (in Season 19's "[[Recap/SouthParkS19E1StunningAndBrave Stunning and Brave]]" and ''VideoGame/SouthParkTheFracturedButWhole''), ''VideoGame/SouthParkTheFracturedButWhole'', with a redesign putting an uncanny emphasis on his lips too), his pedophilia ''was'' [[CrossesTheLineTwice the main joke.]]
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* The entire plot of "Cartoon Wars" (about people panicking over ''WesternAnimation/FamilyGuy'' broadcasting an episode that has Muhammad on it) became a FunnyAneurysmMoment thanks to the "201" debacle. In fact, this and the line about the truck driver liking ''WesternAnimation/FamilyGuy'' because it's not preachy and up its own ass in morals aren't so funny anymore now that ''WesternAnimation/SouthPark'' and ''WesternAnimation/FamilyGuy'' have had their SeasonalRot blamed on being [[{{Anvilicious}} heavy on the morals]]. Also HilariousInHindsight as the show predicted that ''WesternAnimation/FamilyGuy'' would do an episode that has to do with Peter and Islam ("[[Recap/FamilyGuyS11E15TurbanCowboy Turban Cowboy]]"). It didn't have any reference to Muhammad in it, but it is a very happy coincidence (or possibly intentional as Creator/SethMacFarlane has joked about the episode's jabs at him before).
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* The entire plot of "Cartoon Wars" (about people panicking over ''WesternAnimation/FamilyGuy'' broadcasting an episode that has Muhammad on it) became a FunnyAneurysmMoment this thanks to the "201" debacle. In fact, this and the line about the truck driver liking ''WesternAnimation/FamilyGuy'' because it's not preachy and up its own ass in morals aren't so funny anymore now that ''WesternAnimation/SouthPark'' and ''WesternAnimation/FamilyGuy'' have had their SeasonalRot blamed on being [[{{Anvilicious}} heavy on the morals]]. Also HilariousInHindsight as the show predicted that ''WesternAnimation/FamilyGuy'' would do an episode that has to do with Peter and Islam ("[[Recap/FamilyGuyS11E15TurbanCowboy Turban Cowboy]]"). It didn't have any reference to Muhammad in it, but it is a very happy coincidence (or possibly intentional as Creator/SethMacFarlane has joked about the episode's jabs at him before).
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''WesternAnimation/SouthPark'', being the [[CrossesTheLineTwice button-pushing]] and [[RippedFromTheHeadlines topical]] show that it is, is bound to have a few gags that [[HarsherInHindsight become far more confronting than intended]] when HistoryRepeats.
----
* In the episode "[[Recap/SouthParkS1E4BigGayAlsBigGayBoatRide Big Gay Al’s Big Gay Boat Ride]]", a sympathetic portrayal of Stan's homosexual dog Sparky actually shows him as a rapist who forces himself on straight male dogs. They even whimper and cry as they run away. Given the many {{stereotype}}s and fears of homosexual men that view them as insatiable sex monsters who will rape any man or child that gets in their way, this intended VerySpecialEpisode can actually feel like part of the problem now, due to more awareness of the oppression of gay men.
* In a similar vein there's "[[Recap/SouthParkS1E5AnElephantMakesLoveToAPig An Elephant Makes Love To A Pig]]". Chef tells the boys that whenever he's seducing a woman he always starts by getting them "good and drunk" and that the next morning they'd usually regret it. It would only be a few years later that this method of courtship would be recognized as date-rape.
** It's possible the writers may have had this in mind when creating "[[Recap/SouthParkS10E1TheReturnOfChef The Return of Chef]]", where Chef starts coming onto the children in the same way he flirts with women.
* Knowing Trey Parker would later undergo two divorces makes it awkward to see [[AuthorAvatar Stan]] talk about how much divorce sucks in "[[Recap/SouthParkS2E12Clubhouses Clubhouses]]".
* In the Season 2 episode "[[Recap/SouthParkS2E8SummerSucks Summer Sucks]]", Mr. Garrison daydreams about cutting [[Series/LambChopsPlayAlong Lamb Chop]] off Creator/ShariLewis' arm and throwing her on a barbecue. This became much less funny when Lewis passed away less than two months after the episode aired.
* In "[[Recap/SouthParkS2E7CityOnTheEdgeOfForever City on the Edge of Forever]]", Cartman having a false flashback of the events of "[[Recap/SouthParkS1E13CartmansMomIsADirtySlut Cartman’s Mom is a Dirty Slut]]", where his father is John Elway, is a bit more depressing after Season 14 when [[spoiler:it turns out his father really was one of the Denver Broncos. He was Scott Tenorman's father, whom Cartman got killed in Season 5]].
* The entire episode "[[Recap/SouthParkS8E6TheJeffersons The Jeffersons]]" (and the lines from the black man on "[[Recap/SouthParkS2E6TheMexicanStaringFrogOfSouthernSriLanka The Mexican Staring Frog of Southern Sri Lanka]]" who kept telling Jesus that Music/MichaelJackson is still a beloved entertainer, despite being branded as a MemeticMolester), which brutally spoofed Jackson, considering the death of the pop idol and how all the jokes about him being a child molester fell out of favor when he was acquitted in 2005 and when he died in 2009. Considering all the crap he got for his alleged crimes, both in real life and on other TV shows, that make jokes about Jackson being a child molester, ''South Park'' actually had a shocking amount of sympathy for him in the episode "The Jeffersons" as a ManChild who acted this way to make up for the childhood he never had (and Kyle calls "Mr. Jefferson" out on acting like a kid when really he should be caring for the child he has).
* The Season 5 episode "[[Recap/SouthParkS5E7ProperCondomUse Proper Condom Use]]" has parents pushing for sex ed to be taught to the younger grades. How young? Try "kindergarten".[[note]]Which Chef finds appalling, as he believes that kids should be kids and not worry about sexual matters until they find out about it for themselves.[[/note]] It was just a joke about how insane the need for teaching sex ed to younger children can be pushed. That is until some schools actually ''proposed'' having sex ed classes for 1st and 2nd graders. However, this was more centered on child molestation and what to do if you or someone you know is being sexually molested.
* One of the last scenes of "[[Recap/SouthParkS5E14ButtersVeryOwnEpisode Butters' Very Own Episode]]" has Gary Condit, [=JonBenet=] Ramsey's parents, and UsefulNotes/OJSimpson being called out quite viciously and angrily for being murderers who lie through their teeth while playing the victim card. Though it was basically conventional wisdom at the time that Condit and the Ramseys were guilty liars, it has since that it has been confirmed that the Ramseys and Condit were innocent victims who were ConvictedByPublicOpinion, making their call-outs in the episode not ''nearly'' as funny and biting when viewed today. This revelation came too late for Patsy Ramsey, having died of ovarian cancer. [[http://www.nytimes.com/2011/09/25/magazine/talk-trey-parker-and-matt-stone-of-south-park.html?_r=0 Matt Stone and Trey Parker have gone on record saying that they deeply regret this.]]
* In "[[Recap/SouthParkS6E1JaredHasAides Jared Has Aides]]", after a misunderstanding, Jared Fogle is fired from his position as a Subway spokesman because people think he wants to give people AIDS, including children. Several lines of this episode become cringe-worthy after Subway cut ties with Jared after he had his home searched by the FBI under suspicion of possessing child pornography. He was subsequently charged and pled guilty of it and having sex with minors:
-->'''Subway Rep:''' Mr. Jared's views do not necessarily reflect the views of the Subway company.
-->'''Tuong Lu Kim:''' I'm no having Jared in my City Wok! Don't you know? Everyone hates him now that he want to give AIDS to children!
** Naturally, the next times Jared showed up (in Season 19's "[[Recap/SouthParkS19E1StunningAndBrave Stunning and Brave]]" and ''VideoGame/SouthParkTheFracturedButWhole''), his pedophilia ''was'' [[CrossesTheLineTwice the main joke.]]
* In an in-universe example of this, the revelation in the WhamEpisode "[[Recap/SouthParkS14E6TwoHundredOne 201]]" completely twists the climax of "[[Recap/SouthParkS5E4ScottTenormanMustDie Scott Tenorman Must Die]]" around in a new light. For those who wonder: [[spoiler:Cartman's true father and Scott Tenorman's father are the same. Meaning that Cartman killed his own dad and thus that his his victory in "Scott Tenorman Must Die" was a retroactive PyrrhicVictory.]]
* In "[[Recap/SouthParkS8E3ThePassionOfTheJew The Passion of the Jew]]", Creator/MelGibson is shown as a deranged man who goes after Stan and Kenny for hating ''Film/ThePassionOfTheChrist'' and ends up making a fool of himself in front of everyone in town (even going so far as to act like WesternAnimation/DaffyDuck, back when he was a screwball). In 2006, Gibson was pulled over for drunk driving, and while being arrested, he made anti-Semitic remarks and insulted a female officer by calling her a misogynistic name. In 2010, he's taped making racial and sexist slurs and screamed at his wife while threatening her, in a way that is scarily similar to his insane depiction.
* This one goes to ''WesternAnimation/SouthParkBiggerLongerAndUncut''; in light of the cyber-attacks on Sony Pictures allegedly by North Korea over the film ''Film/TheInterview'', the plot about going to war over a movie doesn't seem too farfetched anymore. In a related note, the "Cartoon Wars" two-parter features an episode of ''WesternAnimation/FamilyGuy'' getting pulled after it receives terrorist threats due to its depiction of Muhammad. ''The Interview'' ended up getting pulled from theaters due to terrorist threats over its depiction of Kim Jong-un.
* In the commentaries, Creator/TreyParkerAndMattStone noted that of all the early episodes, the only one that's ''more'' edgy nowadays and which they probably wouldn't be able to get away with now is "[[Recap/SouthParkS1E3Volcano Volcano]]" because it features [[UsefulNotes/{{Columbine}} children pointing guns and threatening to shoot each other.]]..Though, since Season 19 concluded with whole ''families'' point guns at each other, they presumably changed their minds about that.
* In "[[Recap/SouthParkS2E12Clubhouses Clubhouses]]", Randy and Sharon briefly separate after a series of arguments. They get back together at the end of the episode. The episode itself is funny... but then along comes "[[Recap/SouthParkS15E7YoureGettingOld You're Getting Old]]", which is "Clubhouses," only more dramatic (and a two-part episode).
* At the end of "[[Recap/SouthParkS5E3SuperBestFriends Super Best Friends]]," the announcer declares that "Their return is assured, for there will always be a need for the Super Best Friends!" After the "200/201" two-parter created a huge controversy over the show's depictions of Muhammad, the network decided [[BannedEpisode "Super Best Friends" would not return to reruns.]]
* The entire plot of "Cartoon Wars" (about people panicking over ''WesternAnimation/FamilyGuy'' broadcasting an episode that has Muhammad on it) became a FunnyAneurysmMoment thanks to the "201" debacle. In fact, this and the line about the truck driver liking ''WesternAnimation/FamilyGuy'' because it's not preachy and up its own ass in morals aren't so funny anymore now that ''WesternAnimation/SouthPark'' and ''WesternAnimation/FamilyGuy'' have had their SeasonalRot blamed on being [[{{Anvilicious}} heavy on the morals]]. Also HilariousInHindsight as the show predicted that ''WesternAnimation/FamilyGuy'' would do an episode that has to do with Peter and Islam ("[[Recap/FamilyGuyS11E15TurbanCowboy Turban Cowboy]]"). It didn't have any reference to Muhammad in it, but it is a very happy coincidence (or possibly intentional as Creator/SethMacFarlane has joked about the episode's jabs at him before).
** The cancellation of the release of ''Film/TheInterview'' due to potential terrorist threats disturbingly mirrors the reasons for the conflict of this episode, just replace UsefulNotes/OsamaBinLaden with Kim Jong Un.
** This becomes ''even less'' funny after the [[https://en.wikipedia.org/wiki/Charlie_Hebdo_shooting Charlie Hebdo massacre]]. And even less funny after that following [[https://en.wikipedia.org/wiki/November_2015_Paris_attacks the November 2015 Paris tragedy]].
* At the end of "[[Recap/SouthParkS6E6ProfessorChaos Professor Chaos]]", we are abruptly asked, "Which of these six South Park residents was killed, and will never be seen again?" Since this is a parody of cliffhanger endings, the answer is immediately given as Ms. Choksondik. Besides her, the suspects were the Mayor, Officer Barbrady, Jimbo, Mr. Garrison, and... Chef, which wouldn't be true until four years later.
* As [[NauseaFuel gross]] as the "stick food up your butt and shit out your mouth" concept in "[[Recap/SouthParkS6E8RedHotCatholicLove Red Hot Catholic Love]]" was, it was at least ridiculous enough to be seen as impossible -- until a video on ''Tosh.0'' proved that vomiting up feces is physically possible.
* In "[[Recap/SouthParkS4E12TrapperKeeper Trapper Keeper]]", a man under the alias Bill Cosby comes to South Park pretends to want to be Cartman's friend. And Cartman responds "Nah, my mom says I'm not allowed to have male friends over thirty." This line becomes a lot less funny after the rape allegations against Creator/BillCosby.[[note]]Although it could also be a CallBack to the events of "Cartman Joins NAMBLA".[[/note]]
* More of a "Heartwarming Aneurysm Moment", but remember all of those adorable scenes in Season 20 focusing on the blooming romance between Cartman and Heidi, and how dedicated he was to her? Try watching them after "[[Recap/SouthParkS21E6SonsAWitches Sons a Witches]]" or "[[Recap/SouthParkS21E7DoublingDown Doubling Down]]", when we see just how badly the relationship has fallen apart, especially as he gets worse every episode.
** One specific example is when they start the "Let's Come Together as a School" campaign which has Heidi mimicking Cartman's voice, pronouncing school like "skew." This is sort of horrible to think of in the context of Heidi [[DistaffCounterpart essentially transforming into Cartman]] the latter half of season 21 and hating herself over it.
* In "[[Recap/SouthParkS4E17AVeryCrappyChristmas A Very Crappy Christmas]]", Stan pokes fun at Cartman during his impersonation of the latter with Kyle by making fat jokes for a recording project, one of the lines being "I don't need to take that kind of shit from a Jew!". This was rather hilarious until the season 19 episode "Truth and Advertising" where Stan yells '''Fuck You Kyle!!!''' in a voice way too similar to Cartman without trying to impersonate him this time and actually showing genuine hostility towards Kyle, then getting into a fistfight.
* A RunningGag in season 20 was the AudienceReactions to ''Franchise/StarWars'': ''Film/TheForceAwakens'' varying wildly, with many wondering if the film was really as good as when they first saw it. This gag has lost much of its humor as of the release of the sequel, ''Film/TheLastJedi'', which has gotten a major case of CriticalDissonance; becoming the lowest-ranked installment by audiences on Rotten Tomatoes and highlighting many issues with the series' BrokenBase. This reception being inverted as of the release of ''Film/TheRiseOfSkywalker'' can double as this and HilariousInHindsight.
* The fourth season episode "[[Recap/SouthParkS4E8SomethingYouCanDoWithYourFinger Something You Can Do With Your Finger]]" has a joke about the girls of South Park saying that they would be much more excited about meeting Matt Lauer than the new boy band that the boys are trying to start. The aneurysm then occurred in 2017 when Lauer was fired from his position at NBC due to his long history of sexual harassment towards his female coworkers. More concerning is the girls' mouth animations make their screams look more frightened than excited, and the screaming also sounded like they were horrified, too.
* Also in the fourth season in the episode "[[Recap/SouthParkS4E6CherokeeHairTampons Cherokee Hair Tampons]]" when Mr. Garrison is given leave from his job as 3rd grade teacher. He goes to [[TurnInYourBadge turns in his badge]] and gun [puts revolver on table], but he's told that "most teachers ''do not carry a gun!''", demonstrating what a {{Cloudcuckoolander}} he is. As of 2013, some groups ''are'' pushing for teachers to be allowed to carry guns in the wake of school shooting tragedies.
* In the season 15 episode "[[Recap/SouthParkS15E14ThePoorKid The Poor Kid]]", Kenny, his brother, and sister and Cartman are all placed in a group home run by exaggeratedly abusive and strict foster parents who punish them by spraying Dr. Pepper in their basement and force them to clean the house extremely spotless from top to bottom. It was (mostly) funny to watch but in light of the news of a California couple who systematically abused 12 of their 13 kids in an almost similar fashion, the episode would been seen as hard to watch.
* "[[Recap/SouthParkS3E6SexualHarassmentPanda Sexual Harassment Panda]]", while already dealing with touchy subject matter, becomes even harder to watch in light of the [=#MeToo=] movement, where sexual harassment accusations, particularly against public figures, have become even more prominent in the news. Particularly troubling is the show's insinuation that victims are exaggerating or inventing their claims, possibly at the instigation of money hungry lawyers. This is a real life argument often used to silence victims and protect the powerful and famous from facing the consequences of their actions.
* "[[Recap/SouthParkS10E6Manbearpig Manbearpig]]" manages to be this both in a meta sense and in-universe through the power of RealLifeWritesThePlot. The titular cryptid is a metaphor for climate change, which wasn't as widely supported in 2006 as it was in later years. Thus, environmentalist UsefulNotes/AlGore was portrayed as a friendless {{Cloudcuckoolander}} making things up so people would give him attention. While the theory of global warming is still heavily debated, more science has come out in recent years in support of the Earth warming up, with some people noticing more drastic weather changes. To reflect these changing politics, the episode "[[Recap/SouthParkS22E6TimeToGetCereal Time to Get Cereal]]" released in 2018 confirmed that Manbearpig [[spoiler:[[TheCuckoolanderWasRight is real]] and is a greater threat than the boys ever predicted, murdering South Park residents and apparently even being a demon straight from {{Hell}}. With Al Gore having given up the fight, the ''boys'' now have to convince the town that Manbearpig is real... [[CassandraTruth which, of course, many people don't still believe.]]]]
** This can also apply to the episode [[Recap/SouthParkS9E8TwoDaysBeforeTheDayAfterTomorrow "Two Days Before The Day After Tomorrow"]], where various characters mistakenly believe that a massive climate shift is coming on and start crying out "We didn't listen!" in fits of self-pity.
** ''Any'' early episode with anti-environmentalist, global warming skeptic sentiment could probably fall into this, given how reports of species extinction and drastic weather changes are making that sentiment less acceptable.
* The Video game, ''VideoGame/SouthParkTheStickOfTruth'', has Princess Kenny, who served as a parody of Daenerys Targaryen of ''Series/GameOfThrones'' during the "Black Friday" trilogy, pull a FaceHeelTurn for no reason other than a outrageous backstory she made up in the last second and becomes the FinalBoss leading to many hilarious moments. This can become very uncomfortable after watching Daenerys Targaryen, the character Kenny is parodying, [[spoiler:pull a FaceHeelTurn in "[[Recap/GameOfThronesS8E5TheBells The Bells]]" and slaughter thousands of innocent people with her dragon.]]
* A RunningGag from the show's early days was Mr. Garrison asking the mayor if they can "kill all the Mexicans". Decades later, Mr. Garrison would become a {{parody}} of UsefulNotes/DonaldTrump, and one of the most horrific things to come out of the Trump Administration would be [[https://en.wikipedia.org/wiki/Trump_administration_family_separation_policy the displacement and detainment of countless Mexican children in inhumane internment camps at the US / Mexico border.]] and it's considered less funny after a mass shooting in El Paso, Texas on June 4th, 2019 in which 22 people were killed in an act of domestic terrorism. The shooter, Patrick Crusius, stated that "he was out to kill as many Mexicans as he could." The anti-Mexican racism of the administration's internment camps would later be tackled in the Season 23 premiere.
* "[[Recap/SouthParkS23E2BandInChina Band in China]]"
** Less than a week after the episode mocked how easily American media gives in to Chinese censorship came the boycott of Creator/BlizzardEntertainment for [[https://www.bloomberg.com/news/articles/2019-10-09/gamers-call-for-boycott-of-blizzard-after-hong-kong-protest-ban banning a player for supporting Hong Kong's protests against the Chinese government.]]
** Randy's already-unsettling journey to China becomes more cringeworthy after "Pandemic Special," which revealed that Randy became PatientZero for the COVID-19 virus after [[ItMakesSenseInContext a drug-induced spree with Mickey Mouse.]] It also makes it harder to watch the subsequent episodes that feature Randy in close contact with people, particularly "Shots!!!", the episode immediately following "Band In China" where he throws a parade during a period when he would be contagious.
* "[[Recap/SouthParkS21E3HolidaySpecial Holiday Special]]" has Randy protesting Columbus Day and invoking the destruction of Columbus' statues, before being revealed as a fanboy of the Italian navigator. Flash forward to June 2020 and the rage against Columbus becomes relevant again as the aftermath of the protests for the death of George Floyd: they resulted in the vandalizing or toppling of [[https://en.wikipedia.org/wiki/List_of_monuments_and_memorials_removed_during_the_George_Floyd_protests many monuments]] of several historical figures, not only Columbus but many others including Winston Churchill and Mahatma Gandhi.
* In "My Future Self n Me" parents, including Randy, went to ridiculous extremes to get their kids to not use drugs such as teaching them drugs will make you a terrorist. Come Season 23, Randy becomes a terrorist to profit off his weed farm.
* In "Where My Country Gone?", Canada builds a wall to keep the Americans out. While not a literal wall, the Trump administration's botched initial UsefulNotes/COVID19Pandemic response and its long-term effects throughout the year of 2020 has led to the Canadians closing down the US-Canadian Border.
* In "Cherokee Hair Tampons," whenever Stan worries about Kyle dying, Kenny gets mad, claiming (through his muffled voice), "You never seem to care when ''I'' die!" When he gets fed up and leaves, he gets killed by a falling piano. A funny gag at the time, but becomes sadder given the context from two later episodes. First, "Kenny Dies" takes Kenny's death seriously, and Stan is the one who gets the most upset over it, feeling immense guilt when he doesn't visit Kenny at the hospital and Kenny's last words are, "Where's Stan?" Second, "Mysterion Rises" and "Coon vs. Coon and Friends" retcon Kenny's immortality to be the result of a demonic curse, and reveals that not only does Kenny remember every painful death he's experienced, he's extremely pissed that his friends never remember, to the point [[WhoWantsToLiveForever he would rather kill himself than keep living with such a curse]].
* In "The Red Badge of Gayness", Cartman tries to win a bet with Stan and Kyle by turning the town's Civil War reenactment into a real Civil War, which includes leading his troops to storm Washington, D.C. and make President Clinton surrender to the Confederacy. Not so funny 22 years later, when supporters of President Trump, which include neo-Confederates, violently stormed the U.S. Capitol in an attempted coup.
* The attack on the Federal Express store in "T.M.I." has become far less amusing after a former employee attacked a Federal Express facility in Indianapolis in April 2021.
* The campaign against distracted driving in "[[Recap/SouthParkS21E2PutItDown Put It Down]]". The episode already show a bunch of children being run over, but it's even sadder after Jason White died by being run over in "[[Recap/SouthParkS23E6SeasonFinale Season Finale]]".
* "Tsst"'s ending becomes a lot harder to watch when find out what happens to Cartman in his adulthood: [[spoiler: In "Return of COVID", after Bad Future!Cartman sacrifices his current life to save his friends from being cynical and miserable, Good Future!Cartman is revealed to be a homeless shell of his former self, abusing alcohol and shouting obscenities on the street.]] Cesar helped ''avert'' that future for him only for Liane to selfishly revert Cartman back to his original self, putting him back on the path towards his bleak adulthood, all because [[ForWantOfANail Cesar rejected Liane's advances.]]
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* In the episode "[[Recap/SouthParkS1E4BigGayAlsBigGayBoatRide Big Gay Al’s Big Gay Boat Ride]]", a sympathetic portrayal of Stan's homosexual dog Sparky actually shows him as a rapist who forces himself on straight male dogs. They even whimper and cry as they run away. Given the many {{stereotype}}s and fears of homosexual men that view them as insatiable sex monsters who will rape any man or child that gets in their way, this intended VerySpecialEpisode can actually feel like part of the problem now, due to more awareness of the oppression of gay men.
* In a similar vein there's "[[Recap/SouthParkS1E5AnElephantMakesLoveToAPig An Elephant Makes Love To A Pig]]". Chef tells the boys that whenever he's seducing a woman he always starts by getting them "good and drunk" and that the next morning they'd usually regret it. It would only be a few years later that this method of courtship would be recognized as date-rape.
** It's possible the writers may have had this in mind when creating "[[Recap/SouthParkS10E1TheReturnOfChef The Return of Chef]]", where Chef starts coming onto the children in the same way he flirts with women.
* Knowing Trey Parker would later undergo two divorces makes it awkward to see [[AuthorAvatar Stan]] talk about how much divorce sucks in "[[Recap/SouthParkS2E12Clubhouses Clubhouses]]".
* In the Season 2 episode "[[Recap/SouthParkS2E8SummerSucks Summer Sucks]]", Mr. Garrison daydreams about cutting [[Series/LambChopsPlayAlong Lamb Chop]] off Creator/ShariLewis' arm and throwing her on a barbecue. This became much less funny when Lewis passed away less than two months after the episode aired.
* In "[[Recap/SouthParkS2E7CityOnTheEdgeOfForever City on the Edge of Forever]]", Cartman having a false flashback of the events of "[[Recap/SouthParkS1E13CartmansMomIsADirtySlut Cartman’s Mom is a Dirty Slut]]", where his father is John Elway, is a bit more depressing after Season 14 when [[spoiler:it turns out his father really was one of the Denver Broncos. He was Scott Tenorman's father, whom Cartman got killed in Season 5]].
* The entire episode "[[Recap/SouthParkS8E6TheJeffersons The Jeffersons]]" (and the lines from the black man on "[[Recap/SouthParkS2E6TheMexicanStaringFrogOfSouthernSriLanka The Mexican Staring Frog of Southern Sri Lanka]]" who kept telling Jesus that Music/MichaelJackson is still a beloved entertainer, despite being branded as a MemeticMolester), which brutally spoofed Jackson, considering the death of the pop idol and how all the jokes about him being a child molester fell out of favor when he was acquitted in 2005 and when he died in 2009. Considering all the crap he got for his alleged crimes, both in real life and on other TV shows, that make jokes about Jackson being a child molester, ''South Park'' actually had a shocking amount of sympathy for him in the episode "The Jeffersons" as a ManChild who acted this way to make up for the childhood he never had (and Kyle calls "Mr. Jefferson" out on acting like a kid when really he should be caring for the child he has).
* The Season 5 episode "[[Recap/SouthParkS5E7ProperCondomUse Proper Condom Use]]" has parents pushing for sex ed to be taught to the younger grades. How young? Try "kindergarten".[[note]]Which Chef finds appalling, as he believes that kids should be kids and not worry about sexual matters until they find out about it for themselves.[[/note]] It was just a joke about how insane the need for teaching sex ed to younger children can be pushed. That is until some schools actually ''proposed'' having sex ed classes for 1st and 2nd graders. However, this was more centered on child molestation and what to do if you or someone you know is being sexually molested.
* One of the last scenes of "[[Recap/SouthParkS5E14ButtersVeryOwnEpisode Butters' Very Own Episode]]" has Gary Condit, [=JonBenet=] Ramsey's parents, and UsefulNotes/OJSimpson being called out quite viciously and angrily for being murderers who lie through their teeth while playing the victim card. Though it was basically conventional wisdom at the time that Condit and the Ramseys were guilty liars, it has since that it has been confirmed that the Ramseys and Condit were innocent victims who were ConvictedByPublicOpinion, making their call-outs in the episode not ''nearly'' as funny and biting when viewed today. This revelation came too late for Patsy Ramsey, having died of ovarian cancer. [[http://www.nytimes.com/2011/09/25/magazine/talk-trey-parker-and-matt-stone-of-south-park.html?_r=0 Matt Stone and Trey Parker have gone on record saying that they deeply regret this.]]
* In "[[Recap/SouthParkS6E1JaredHasAides Jared Has Aides]]", after a misunderstanding, Jared Fogle is fired from his position as a Subway spokesman because people think he wants to give people AIDS, including children. Several lines of this episode become cringe-worthy after Subway cut ties with Jared after he had his home searched by the FBI under suspicion of possessing child pornography. He was subsequently charged and pled guilty of it and having sex with minors:
-->'''Subway Rep:''' Mr. Jared's views do not necessarily reflect the views of the Subway company.
-->'''Tuong Lu Kim:''' I'm no having Jared in my City Wok! Don't you know? Everyone hates him now that he want to give AIDS to children!
** Naturally, the next times Jared showed up (in Season 19's "[[Recap/SouthParkS19E1StunningAndBrave Stunning and Brave]]" and ''VideoGame/SouthParkTheFracturedButWhole''), his pedophilia ''was'' [[CrossesTheLineTwice the main joke.]]
* In an in-universe example of this, the revelation in the WhamEpisode "[[Recap/SouthParkS14E6TwoHundredOne 201]]" completely twists the climax of "[[Recap/SouthParkS5E4ScottTenormanMustDie Scott Tenorman Must Die]]" around in a new light. For those who wonder: [[spoiler:Cartman's true father and Scott Tenorman's father are the same. Meaning that Cartman killed his own dad and thus that his his victory in "Scott Tenorman Must Die" was a retroactive PyrrhicVictory.]]
* In "[[Recap/SouthParkS8E3ThePassionOfTheJew The Passion of the Jew]]", Creator/MelGibson is shown as a deranged man who goes after Stan and Kenny for hating ''Film/ThePassionOfTheChrist'' and ends up making a fool of himself in front of everyone in town (even going so far as to act like WesternAnimation/DaffyDuck, back when he was a screwball). In 2006, Gibson was pulled over for drunk driving, and while being arrested, he made anti-Semitic remarks and insulted a female officer by calling her a misogynistic name. In 2010, he's taped making racial and sexist slurs and screamed at his wife while threatening her, in a way that is scarily similar to his insane depiction.
* This one goes to ''WesternAnimation/SouthParkBiggerLongerAndUncut''; in light of the cyber-attacks on Sony Pictures allegedly by North Korea over the film ''Film/TheInterview'', the plot about going to war over a movie doesn't seem too farfetched anymore. In a related note, the "Cartoon Wars" two-parter features an episode of ''WesternAnimation/FamilyGuy'' getting pulled after it receives terrorist threats due to its depiction of Muhammad. ''The Interview'' ended up getting pulled from theaters due to terrorist threats over its depiction of Kim Jong-un.
* In the commentaries, Creator/TreyParkerAndMattStone noted that of all the early episodes, the only one that's ''more'' edgy nowadays and which they probably wouldn't be able to get away with now is "[[Recap/SouthParkS1E3Volcano Volcano]]" because it features [[UsefulNotes/{{Columbine}} children pointing guns and threatening to shoot each other.]]..Though, since Season 19 concluded with whole ''families'' point guns at each other, they presumably changed their minds about that.
* In "[[Recap/SouthParkS2E12Clubhouses Clubhouses]]", Randy and Sharon briefly separate after a series of arguments. They get back together at the end of the episode. The episode itself is funny... but then along comes "[[Recap/SouthParkS15E7YoureGettingOld You're Getting Old]]", which is "Clubhouses," only more dramatic (and a two-part episode).
* At the end of "[[Recap/SouthParkS5E3SuperBestFriends Super Best Friends]]," the announcer declares that "Their return is assured, for there will always be a need for the Super Best Friends!" After the "200/201" two-parter created a huge controversy over the show's depictions of Muhammad, the network decided [[BannedEpisode "Super Best Friends" would not return to reruns.]]
* The entire plot of "Cartoon Wars" (about people panicking over ''WesternAnimation/FamilyGuy'' broadcasting an episode that has Muhammad on it) became a FunnyAneurysmMoment thanks to the "201" debacle. In fact, this and the line about the truck driver liking ''WesternAnimation/FamilyGuy'' because it's not preachy and up its own ass in morals aren't so funny anymore now that ''WesternAnimation/SouthPark'' and ''WesternAnimation/FamilyGuy'' have had their SeasonalRot blamed on being [[{{Anvilicious}} heavy on the morals]]. Also HilariousInHindsight as the show predicted that ''WesternAnimation/FamilyGuy'' would do an episode that has to do with Peter and Islam ("[[Recap/FamilyGuyS11E15TurbanCowboy Turban Cowboy]]"). It didn't have any reference to Muhammad in it, but it is a very happy coincidence (or possibly intentional as Creator/SethMacFarlane has joked about the episode's jabs at him before).
** The cancellation of the release of ''Film/TheInterview'' due to potential terrorist threats disturbingly mirrors the reasons for the conflict of this episode, just replace UsefulNotes/OsamaBinLaden with Kim Jong Un.
** This becomes ''even less'' funny after the [[https://en.wikipedia.org/wiki/Charlie_Hebdo_shooting Charlie Hebdo massacre]]. And even less funny after that following [[https://en.wikipedia.org/wiki/November_2015_Paris_attacks the November 2015 Paris tragedy]].
* At the end of "[[Recap/SouthParkS6E6ProfessorChaos Professor Chaos]]", we are abruptly asked, "Which of these six South Park residents was killed, and will never be seen again?" Since this is a parody of cliffhanger endings, the answer is immediately given as Ms. Choksondik. Besides her, the suspects were the Mayor, Officer Barbrady, Jimbo, Mr. Garrison, and... Chef, which wouldn't be true until four years later.
* As [[NauseaFuel gross]] as the "stick food up your butt and shit out your mouth" concept in "[[Recap/SouthParkS6E8RedHotCatholicLove Red Hot Catholic Love]]" was, it was at least ridiculous enough to be seen as impossible -- until a video on ''Tosh.0'' proved that vomiting up feces is physically possible.
* In "[[Recap/SouthParkS4E12TrapperKeeper Trapper Keeper]]", a man under the alias Bill Cosby comes to South Park pretends to want to be Cartman's friend. And Cartman responds "Nah, my mom says I'm not allowed to have male friends over thirty." This line becomes a lot less funny after the rape allegations against Creator/BillCosby.[[note]]Although it could also be a CallBack to the events of "Cartman Joins NAMBLA".[[/note]]
* More of a "Heartwarming Aneurysm Moment", but remember all of those adorable scenes in Season 20 focusing on the blooming romance between Cartman and Heidi, and how dedicated he was to her? Try watching them after "[[Recap/SouthParkS21E6SonsAWitches Sons a Witches]]" or "[[Recap/SouthParkS21E7DoublingDown Doubling Down]]", when we see just how badly the relationship has fallen apart, especially as he gets worse every episode.
** One specific example is when they start the "Let's Come Together as a School" campaign which has Heidi mimicking Cartman's voice, pronouncing school like "skew." This is sort of horrible to think of in the context of Heidi [[DistaffCounterpart essentially transforming into Cartman]] the latter half of season 21 and hating herself over it.
* In "[[Recap/SouthParkS4E17AVeryCrappyChristmas A Very Crappy Christmas]]", Stan pokes fun at Cartman during his impersonation of the latter with Kyle by making fat jokes for a recording project, one of the lines being "I don't need to take that kind of shit from a Jew!". This was rather hilarious until the season 19 episode "Truth and Advertising" where Stan yells '''Fuck You Kyle!!!''' in a voice way too similar to Cartman without trying to impersonate him this time and actually showing genuine hostility towards Kyle, then getting into a fistfight.
* A RunningGag in season 20 was the AudienceReactions to ''Franchise/StarWars'': ''Film/TheForceAwakens'' varying wildly, with many wondering if the film was really as good as when they first saw it. This gag has lost much of its humor as of the release of the sequel, ''Film/TheLastJedi'', which has gotten a major case of CriticalDissonance; becoming the lowest-ranked installment by audiences on Rotten Tomatoes and highlighting many issues with the series' BrokenBase. This reception being inverted as of the release of ''Film/TheRiseOfSkywalker'' can double as this and HilariousInHindsight.
* The fourth season episode "[[Recap/SouthParkS4E8SomethingYouCanDoWithYourFinger Something You Can Do With Your Finger]]" has a joke about the girls of South Park saying that they would be much more excited about meeting Matt Lauer than the new boy band that the boys are trying to start. The aneurysm then occurred in 2017 when Lauer was fired from his position at NBC due to his long history of sexual harassment towards his female coworkers. More concerning is the girls' mouth animations make their screams look more frightened than excited, and the screaming also sounded like they were horrified, too.
* Also in the fourth season in the episode "[[Recap/SouthParkS4E6CherokeeHairTampons Cherokee Hair Tampons]]" when Mr. Garrison is given leave from his job as 3rd grade teacher. He goes to [[TurnInYourBadge turns in his badge]] and gun [puts revolver on table], but he's told that "most teachers ''do not carry a gun!''", demonstrating what a {{Cloudcuckoolander}} he is. As of 2013, some groups ''are'' pushing for teachers to be allowed to carry guns in the wake of school shooting tragedies.
* In the season 15 episode "[[Recap/SouthParkS15E14ThePoorKid The Poor Kid]]", Kenny, his brother, and sister and Cartman are all placed in a group home run by exaggeratedly abusive and strict foster parents who punish them by spraying Dr. Pepper in their basement and force them to clean the house extremely spotless from top to bottom. It was (mostly) funny to watch but in light of the news of a California couple who systematically abused 12 of their 13 kids in an almost similar fashion, the episode would been seen as hard to watch.
* "[[Recap/SouthParkS3E6SexualHarassmentPanda Sexual Harassment Panda]]", while already dealing with touchy subject matter, becomes even harder to watch in light of the [=#MeToo=] movement, where sexual harassment accusations, particularly against public figures, have become even more prominent in the news. Particularly troubling is the show's insinuation that victims are exaggerating or inventing their claims, possibly at the instigation of money hungry lawyers. This is a real life argument often used to silence victims and protect the powerful and famous from facing the consequences of their actions.
* "[[Recap/SouthParkS10E6Manbearpig Manbearpig]]" manages to be this both in a meta sense and in-universe through the power of RealLifeWritesThePlot. The titular cryptid is a metaphor for climate change, which wasn't as widely supported in 2006 as it was in later years. Thus, environmentalist UsefulNotes/AlGore was portrayed as a friendless {{Cloudcuckoolander}} making things up so people would give him attention. While the theory of global warming is still heavily debated, more science has come out in recent years in support of the Earth warming up, with some people noticing more drastic weather changes. To reflect these changing politics, the episode "[[Recap/SouthParkS22E6TimeToGetCereal Time to Get Cereal]]" released in 2018 confirmed that Manbearpig [[spoiler:[[TheCuckoolanderWasRight is real]] and is a greater threat than the boys ever predicted, murdering South Park residents and apparently even being a demon straight from {{Hell}}. With Al Gore having given up the fight, the ''boys'' now have to convince the town that Manbearpig is real... [[CassandraTruth which, of course, many people don't still believe.]]]]
** This can also apply to the episode [[Recap/SouthParkS9E8TwoDaysBeforeTheDayAfterTomorrow "Two Days Before The Day After Tomorrow"]], where various characters mistakenly believe that a massive climate shift is coming on and start crying out "We didn't listen!" in fits of self-pity.
** ''Any'' early episode with anti-environmentalist, global warming skeptic sentiment could probably fall into this, given how reports of species extinction and drastic weather changes are making that sentiment less acceptable.
* The Video game, ''VideoGame/SouthParkTheStickOfTruth'', has Princess Kenny, who served as a parody of Daenerys Targaryen of ''Series/GameOfThrones'' during the "Black Friday" trilogy, pull a FaceHeelTurn for no reason other than a outrageous backstory she made up in the last second and becomes the FinalBoss leading to many hilarious moments. This can become very uncomfortable after watching Daenerys Targaryen, the character Kenny is parodying, [[spoiler:pull a FaceHeelTurn in "[[Recap/GameOfThronesS8E5TheBells The Bells]]" and slaughter thousands of innocent people with her dragon.]]
* A RunningGag from the show's early days was Mr. Garrison asking the mayor if they can "kill all the Mexicans". Decades later, Mr. Garrison would become a {{parody}} of UsefulNotes/DonaldTrump, and one of the most horrific things to come out of the Trump Administration would be [[https://en.wikipedia.org/wiki/Trump_administration_family_separation_policy the displacement and detainment of countless Mexican children in inhumane internment camps at the US / Mexico border.]] and it's considered less funny after a mass shooting in El Paso, Texas on June 4th, 2019 in which 22 people were killed in an act of domestic terrorism. The shooter, Patrick Crusius, stated that "he was out to kill as many Mexicans as he could." The anti-Mexican racism of the administration's internment camps would later be tackled in the Season 23 premiere.
* "[[Recap/SouthParkS23E2BandInChina Band in China]]"
** Less than a week after the episode mocked how easily American media gives in to Chinese censorship came the boycott of Creator/BlizzardEntertainment for [[https://www.bloomberg.com/news/articles/2019-10-09/gamers-call-for-boycott-of-blizzard-after-hong-kong-protest-ban banning a player for supporting Hong Kong's protests against the Chinese government.]]
** Randy's already-unsettling journey to China becomes more cringeworthy after "Pandemic Special," which revealed that Randy became PatientZero for the COVID-19 virus after [[ItMakesSenseInContext a drug-induced spree with Mickey Mouse.]] It also makes it harder to watch the subsequent episodes that feature Randy in close contact with people, particularly "Shots!!!", the episode immediately following "Band In China" where he throws a parade during a period when he would be contagious.
* "[[Recap/SouthParkS21E3HolidaySpecial Holiday Special]]" has Randy protesting Columbus Day and invoking the destruction of Columbus' statues, before being revealed as a fanboy of the Italian navigator. Flash forward to June 2020 and the rage against Columbus becomes relevant again as the aftermath of the protests for the death of George Floyd: they resulted in the vandalizing or toppling of [[https://en.wikipedia.org/wiki/List_of_monuments_and_memorials_removed_during_the_George_Floyd_protests many monuments]] of several historical figures, not only Columbus but many others including Winston Churchill and Mahatma Gandhi.
* In "My Future Self n Me" parents, including Randy, went to ridiculous extremes to get their kids to not use drugs such as teaching them drugs will make you a terrorist. Come Season 23, Randy becomes a terrorist to profit off his weed farm.
* In "Where My Country Gone?", Canada builds a wall to keep the Americans out. While not a literal wall, the Trump administration's botched initial UsefulNotes/COVID19Pandemic response and its long-term effects throughout the year of 2020 has led to the Canadians closing down the US-Canadian Border.
* In "Cherokee Hair Tampons," whenever Stan worries about Kyle dying, Kenny gets mad, claiming (through his muffled voice), "You never seem to care when ''I'' die!" When he gets fed up and leaves, he gets killed by a falling piano. A funny gag at the time, but becomes sadder given the context from two later episodes. First, "Kenny Dies" takes Kenny's death seriously, and Stan is the one who gets the most upset over it, feeling immense guilt when he doesn't visit Kenny at the hospital and Kenny's last words are, "Where's Stan?" Second, "Mysterion Rises" and "Coon vs. Coon and Friends" retcon Kenny's immortality to be the result of a demonic curse, and reveals that not only does Kenny remember every painful death he's experienced, he's extremely pissed that his friends never remember, to the point [[WhoWantsToLiveForever he would rather kill himself than keep living with such a curse]].
* In "The Red Badge of Gayness", Cartman tries to win a bet with Stan and Kyle by turning the town's Civil War reenactment into a real Civil War, which includes leading his troops to storm Washington, D.C. and make President Clinton surrender to the Confederacy. Not so funny 22 years later, when supporters of President Trump, which include neo-Confederates, violently stormed the U.S. Capitol in an attempted coup.
* The attack on the Federal Express store in "T.M.I." has become far less amusing after a former employee attacked a Federal Express facility in Indianapolis in April 2021.
* The campaign against distracted driving in "[[Recap/SouthParkS21E2PutItDown Put It Down]]". The episode already show a bunch of children being run over, but it's even sadder after Jason White died by being run over in "[[Recap/SouthParkS23E6SeasonFinale Season Finale]]".
* "Tsst"'s ending becomes a lot harder to watch when find out what happens to Cartman in his adulthood: [[spoiler: In "Return of COVID", after Bad Future!Cartman sacrifices his current life to save his friends from being cynical and miserable, Good Future!Cartman is revealed to be a homeless shell of his former self, abusing alcohol and shouting obscenities on the street.]] Cesar helped ''avert'' that future for him only for Liane to selfishly revert Cartman back to his original self, putting him back on the path towards his bleak adulthood, all because [[ForWantOfANail Cesar rejected Liane's advances.]]
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