History DisabledInTheAdaptation / WithPearlAndRubyGlowing

* [[WesternAnimation/Sing2 Porscha Crystal]] has no sense of smell, allowing her father to trick her into believing that her fellow "co-stars" tortures was just very elaborate make up as she couldn't smell any of the gore.

* [[WesternAnimation/StrawberryShortcake Gingersnap]] cut off her leg for her and her friends to eat when they ran out of food when stranded on the Ark's island.

* [[WesternAnimation/LooneyTunes Daffy]] is autistic, has ADD, and has narcissistic "fleas" that he picked up from his mother. Sylvester has purely obsessional OCD which gives him intrusive throughts about hurting Tweety.

* [[WesternAnimation/LooneyTunes Daffy]] is autistic, has ADD, and has narcissistic "fleas" that he picked up from his mother.

* [[WesternAnimation/StevenUniverse Spinel]] has Borderline Personality Disorder. Ruby and Sapphire have achondroplasic dwarfism. Jasper mentions two of her sisters (heavily implied to be [[RelatedInTheAdaptation Amethyst and Carnelian]]) are little people and that a third (presumably Skinny Jasper) has some condition preventing weight gain, and she and at least some of her siblings, possibly including them, are intersex (definitely including Lace Amethyst and Amethysts 8XJ, 8XK, and 8XL). Malachite was Jasper and Lapis' child, born with sirenomelia and missing organs which resulted in her death within a week. Aquamarine has Dissociative Identity Disorder, with Bluebird Azurite being her alternate personality as a result of being molested by Eyeball Ruby, who is her biological mother in this setting.

Several characters in ''Fanfic/WithPearlAndRubyGlowing'', unlike canon, are [[DisabledInTheAdaptation disabled or have disorders]], some as a result of people assaulting them. Some were even assaulted specifically because of their disabilities. Other disabilities are references to character designs from their source material or behavior shown in canon.

* [[WesternAnimation/LooneyTunes Daffy]] has autism, ADD, and narcissistic "fleas" that he picked up from his mother.
* [[WesternAnimation/BigHero6 Baymax]] has autism, which gives him flat, robotic mannerisms.

* Both WesternAnimation/WallaceAndGromit have autism; Gromit is also mute, which may or may not be connected to the autism.

* [[Series/DrakeAndJosh Josh]] mentions having autism, and Megan is implied to have some kind of cluster B disorder.

* [[Series/ICarly Spencer Shay]] has autism and schizophrenia that causes him to hallucinate fire. He also mentions that Miss Ackerman has bipolar depression and Borderline Personality Disorder.
* [[Franchise/KungFuPanda Viper]] has two prosthetic arms and Po mentions in "Friends" that Tigress has autism.

* [[WesternAnimation/FostersHomeForImaginaryFriends Goo]] has autism and ADHD; kids her own age think she's weird because of it, but she gets along well with younger children and people older than her. Wilt has albinism along with his canon missing arm and blind eye.
* [[WesternAnimation/MissingLink Lionel]], [[WesternAnimation/StarVsTheForcesOfEvil Toffee]], [[WesternAnimation/TheLegendOfKorra Iroh II]], and [[WesternAnimation/CraigOfTheCreek Mark]] were castrated/emasculated. [[spoiler:[[WesternAnimation/InsideOut Riley]] is rendered infertile after suffering a ruptured uterus.]]

* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Trixie]] has Narcissistic Personality Disorder; Flim and Flam make it clear that it doesn't make her a bad person. The population of Equestria are prone to a FictionalDisability which makes it hard for them to conceive and carry boy babies to term, so there are a lot more women there. Dr. Hooves mentions that his wife, likely Derpy, is autistic.

* [[WesternAnimation/IceAge Sid]] was sent to Karlag because of his Waardenburg Syndrome, as well as being Koryo-saram. Momma Rex is implied to have autism or something similar, as she's mute and has no control over her temper, proper treatment not being available at the time. Roger is implied to have some form of mental disability.

* [[WesternAnimation/TheOwlHouse Edric and Emira]] were born with a lot of health problems; both required heart surgery, Emira has Turner Syndrome, and Edric's dairy allergy briefly mentioned in canon is possibly lethal. The Collector has clinical kleptomania, autism, separation anxiety, and B-12 deficiency.

* [[WesternAnimation/{{Encanto}} Mirabel]] has Narcissistic Personality Disorder (as an analogy to her lacking magic in the movie) and her Chosen Person is Antonio. She's worried that it makes her dangerous or a bad person, but [[WesternAnimation/MyLittlePonyFriendshipIsMagic Dr. Hooves]] assures her that it doesn't and implies he has it himself. Beatriz (the name given to the character made from the original design of Isabela) also probably has it though may not have been diagnosed officially. Bruno has OCD and hyper-empathy, and Dolores is autistic with sensitivity to loud noises (as an analogy to her gift in the movie).

* WebAnimation/{{Ena}} has autism and bipolar disorder, which causes her to be a MoodSwinger.

* [[WesternAnimation/GravedaleHigh Vinnie]] has Von Willebrand Syndrome. Max mentions in his victim impact statement that he teaches a special ed class, with the others disorders being mentioned in a later intermission chapter. Frankentyke has achondroplasia, Reggie has anxiety, Blanche has bipolar disorder, Duzer is in remission from melanoma, Cleofatra has a thyroid problem, J.P. Ghastly has pituitary gland problems and cyanosis, and Sid has autism and ADD. (Gill isn't disabled but is a drug user.)

* [[Franchise/{{Barbie}} Skipper Roberts]] has Swyer Syndrome, which means she has no ovaries. [[WesternAnimation/BarbieMariposa Rayna]] is autistic, Rayla has butterfly syndrome/epidermolysis bullosa, Coral is anorexic and suffers from Fish Odour Syndrome, and Anemone has severe tinnitus. The Guardian Fairies ([[CompositeCharacter who are a singular body here]]) and Mariposa both have DID; the Guardian Fairies are a system and Mariposa develops a Willa introject after the trauma of finding Willa's body. The original Willa had lupus. Catania recovered from physical injury requiring a wheelchair but kept the chair because now she has glass delusion. Barbie suffered a psychotic breakdown after Kelly's death and started to think she was actually her friend Amelia, and [[WesternAnimation/BarbieAsThePrincessAndThePauper Anneliese]] mentions having had a similar delusion, implied to be that she thought she was Erika. [[WesternAnimation/BarbieAndTheSecretDoor Malucia]] has achondroplasic dwarfism with numerous symptoms, autism, ADHD, celiac disease, delayed puberty, and Freeman-Sheldon syndrome. [[WesternAnimation/BarbiePrincessCharmSchool Emily Willows]] thinks she might have autism but her family can't afford an official diagnosis. [[WesternAnimation/BarbieAndTheDiamondCastle Melody]] has mirror image agnosia. [[WesternAnimation/BarbieAndTheMagicOfPegasus Annika]] has bipolar disorder with hallucination symptoms. [[WesternAnimation/BarbieInTheNutcracker Eric]] was born with only one arm.

* [[WesternAnimation/StrawberryShortcake Gingersnap]] cut off her leg to eat when she ran out of food when stranded at the Ark's island.

* [[WesternAnimation/MonsterHigh Howleen]] became blind when her assailant beat her and gave her brain damage.

* [[WesternAnimation/StrawberryShortcake Gingersnap]] cut off her leg when she ran out of food when stranded at the Ark's island.

* WesternAnimation/{{Pinocchio}} has genital agenesis, causing the Coachman to angrily say he's not a "real boy" in a reference to the movie, though the narrative makes it clear he is. Foulfellow was blinded when the Coachman poked him in the eyes with a lit cigar for turning him in, as a reference to what happens to him in the original book.

* WesternAnimation/{{Pinocchio}} has genital agenesis, causing the Coachman to angrily say he's not a "real boy" in a reference to the movie, though the narrative makes it clear he is.

* [[WesternAnimation/DragonTales Ord]] has Down syndrome.

* [[WesternAnimation/ThePowerpuffGirls1998 Bunny]], instead of being an unstable ArtificialHuman, has Down syndrome and scoliosis.

* [[WebAnimation/HazbinHotel Angel Dust]] is a cis man with a medical issue which made him grow breasts. He also lost an eye to Valentino's goons, while in canon one of his eyes is just black, and they also mutilated his feet.

* [[WesternAnimation/RegularShow Hi-Five Ghost]] has an amputated arm.

* [[WesternAnimation/ThePowerpuffGirls1998 Bunny]], instead of being an unstable ArtificialHuman, has Down syndrome and scoliosis.
* [[WesternAnimation/TheOwlHouse The Collector]] has kleptomania, autism, separation anxiety, and B-12 deficiency.

* [[WesternAnimation/ThePowerpuffGirls1998 Bunny]], instead of being an unstable clone, has Down syndrome and scoliosis.

* [[WesternAnimation/TheOwlHouse Edric and Emira]] were born with a lot of health problems; both required heart surgery, Emira has Turner Syndrome, and Edric's dairy allergy briefly mentioned in canon is possibly lethal.

* The [[Music/SkiesForeverBlue boy and girl]]—here named Taffy and Skye respectively— are both autistic, the former being non-verbal and using a speech device.

* The [[Music/SkiesForeverBlue]] music video’s boy and girl are both autistic, the former being non-verbal and using a speech device.