These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: What's Happening!!
Acceptable Targets: Rerun and Shirley are mocked—and they insult each other—because of their weight. Mrs. Thomas is also obese, but nothing much is said about her weight.
Fear of Mrs. Thomas is probably what prevented that; would you make fun of her weight?
Even though this is true, she was caught and punished severely for taking an It's Not What You Think moment (in this case, her friend Robin wanted to run away from home, but asked Dee to talk to the guidance counselor, who thought that it was Dee who wanted to run away) and turning it to her advantage to get Raj and Mrs. Thomas to be nicer to her and buy her things.
Crowning Moment of Funny: the episode where Rerun tries out for the dance group and makes it because the other dancers want him for comic relief because of his weight. Dwayne finds out and tells Rerun and Raj, who sabotages the show by pretending he's Rerun. MUCH Hilarity Ensues
Jump the Shark: When the three friends went to college and two characters, Big Earl and Little Earl, were introduced many fans claim the show lost its original charm.
Tearjerker: The episode where Dee, Yes THAT Dee, befriends a rather gruff old man while her brother is in the hospital. Her reaction to his death, in addition to being a Tearjerker, is also a Crowning Moment of Heartwarming . Dee tells the man's daughter that he'll be all right because you can't get hurt sliding into a cloud.