These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: Bio Ship Paladin
Anti-Climax Boss: The Final Boss, Tatsuriki, both slower and possesses less firepower than the previous two bosses. Additionally, it moves very predictably and slowly and lacks the capacity to hit much of the screen at one time, making it a sitting duck for the manual "Beam" shots.
Game Breaker: The manual-target explosive blasts could decimate bosses and Giant Mooks in seconds, AND defend you from projectiles. It takes some practice to master it, though.
That One Level: Any level with asteroids/rocks, ESPECIALLY brown ones. All rocks explode into shrapnel when destroyed, and the shrapnel can do a lot of damage.