Trivia: The Sarah Silverman Program
- Acting for Two: The young actress who plays Sarah's daughter in "Not Without My Daughter" is the same actress who plays the child version of Sarah in the Pilot and other episodes.
- The Danza: Applies to most of the cast, first and last (but not middle) name for the title character and her sister.
- Hey, It's That Guy!: Various cast members from Tim & Eric Awesome Show, Great Job! have made appearances on the show, Tim Heidecker himself among the most notable. Since this is arguably the sister show to Mr. Show (MRS Show?!), many familiar faces pop up.
- Hey, It's That Voice!: Andy and Ollie Pesto are on the show, as is Kim Possible's Cousin Larry.
- Missing Episode: Episodes 2 and 5 are missing from Netflix for unknown reasons.
- Real-Life Relative: Sarah Silverman and Laura Silverman. it's not a coincidence.
- Although in real life, Laura is Sarah's older sister.
- Screwed by the Network: Despite its immediate and continual success, networks rarely showed reruns of the episodes for very long, and after every season ended, all episodes and ads and discussion of the show would be dropped for months at a time. Fans were in a constant state of not knowing whether or not the show had been cancelled yet. After a third season, the show's episodes were quickly pulled away again ... only with a quiet message saying the show has been cancelled.