Trivia: The Adventures of Milo and Otis
- Enforced Method Acting: Allegedly, many of the stunts were done by actually putting the animal actors in danger and then filming. The other wiki mentions the allegations but notes that nothing was ever proven. The Japanese version has a good bit of footage deemed too nasty for the American cut, including a much more violent fight between the pug and the bear, and one kitten that reportedly had its foot deliberately broken.
- Hey, It's That Voice! / Hey, It's That Guy!: The English dub of the movie has Dudley Moore as the narrator.
- Pop-Star Composer: Ryuichi Sakamoto, from Synthpop band Yellow Magic Orchestra, composed the music for the original Japanese release.
- Public Domain Soundtrack: Most of the score for the version released outside of Japan consists of classical music for which the copyrights had long since elapsed.