While Emira gets a pass due to being at Dr. Bride's clinic, Sioux and Veronica are the only other LOWTH members who don't participate in interrogating Cross with the rest of the team.
I.M.P. was meant to appear earlier where Piniet would've hired them to assassinate Luz. This was changed to Loona getting trapped on the Isles which thematically fit the story better.
Before Mel's gang was created, Loona was originally brought to the Boiling Isles by Mel only to her to forget about the hellhound and leave her behind.
Due to the liberties taken from adjusting the Helluva Boss timeline to that of Luz Clawthorne, Moxxie hasn't met Millie and I.M.P. hasn't been formed yet.
Cruella being a dalmatian demon was made for the irony of it.