- Acting for Two: James Marsden plays Steve in the first season, Steve's twin Ben in the second season, and both in the third season.
- Actor-Shared Background: Jen has undergone a double mastectomy in the past, just like Christina Applegate. However, while the character's mastectomy was a purely preventative measure, Applegate actually was diagnosed with cancer in one breast. Both the character and Applegate share an inherited genetic trait that can cause breast cancer with their mothers; while Jen's mother died, Applegate's real-life mother is a breast cancer survivor. Both Jen and Applegate also trained as dancers in their youth.
- Queer Character, Queer Actor: Natalie Morales, who is queer and uses she/they pronouns, plays Judy's queer love interest, Michelle.
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