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Tear Jerker: Indiana Jones And The Kingdom Of The Crystal Skull
Indy looking at a photo of the late Henry, Sr., complete with the musical cue from the previous film.
Early on in the movie, Indy reveals that Marcus and his father both died, and with Mac betraying him, he's completely alone. This brought tears, only for a reprise of crying when Indy finds Marion and Mutt again.
The line by Indy's friend Charles (Jim Broadbent): We seem to have reached the age where life stops giving us things and starts taking them away.
Thankfully that later lead to a happy subversion (as well as a happy tear-jearker) when Indy found he had a son, and both he and Charles get their jobs back.
Not to mention the way John William's score is precisely aimed to work these moments to the hilt. I now can't hear the Grail theme without tearing up at the thought of Henry Jones Sr's death.
