This is based on opinion. Please don't list it on a work's trope example list.
Tear Jerker / Final Fantasy Adventure
Oh lord, where to begin? This game is one of the saddest ever seen on the Game Boy.
Willie dies right off the bat.
The heroine is left alone in the world because Hasim, her guardian, dies. She's forced to join with the first person she sees after that, since she cannot fight on her own.
Amanda, your best friend, is turned into a monster and begs you to kill her.
Lester, who spends a long time trapped in the form of a bird, is given the news that his sister is dead shortly after he's freed. After you beat Davius he says he's going to stay in Jadd and play requiem for her.
An example from a parenting magazine published in 1992 mentioned how the submitter's young kid got the game for Christmas and played it obsessively to completion. When she came into the room to tell him it was time to turn the Game Boy off, she was greeted with sad music coming from the system and saw her son in tears because of what happened through the game — even adding the main character giving up his Chocobo to the list of tearjerkers.