Basic Trope: Characters who spend the majority of their time alone are considered to be social deviants.
Straight: Lorenzo spends the vast majority of his time alone, and he's considered to be an outcast and freak.
Exaggerated: Lorenzo spends the vast majority of his time alone, and he's considered to be a villain who schemes against others.
Although Lorenzo has only a few friends, he is still considered a bit weird whenever he's alone.
Although others don't mind Lorenzo's solitary nature, they are a bit concerned about him.
Humans are social animals, and the others are naturally inclined to assume that Lorenzo is mentally unbalanced.
Lorenzo is a recluse who lives off the grid in a cabin in the woods outside of town, hunts and grows his own food, has no job, and wears animal skins he made himself. He's actually a friendly guy, but nobody wants to talk to him due to his bizarre lifestyle.
Double Subverted: ...or so he'd seem to anyone first getting to know him. He's actually even more of a freak than anyone guessed when he still spent all his time alone.
Lorenzo is treated as an almost imaginary figure amongst other people.
Lorenzo is given cold unfriendly glares from everyone because he doesn't have a Facebook page.
The people are portrayed as ultimate paragons of virtue because they use The Power of Friendship to overcome obstacles while Lorenzo is portrayed as a irredeemable villain because of his preference of solitude.
Zig Zagged: Sometimes, others treat Lorenzo with disdain and suspicion whenever he's alone, and sometimes, they relent when Lorenzo doesn't cause any trouble, although that doesn't stop others from continuously discouraging his behavior.
Averted: No one thinks of Lorenzo as a freak.
"People think loners are freaks, and we need a stock freaky character. Let's make Lorenzo not talk to anyone."
Exploited: Mark, a villain, makes nasty rumors about a solitary Lorenzo planning to commit genocide on the planet so that everyone can look up to him.
Defied: "He may be a loner, but I'm pretty sure he's not some freakish monster."
"Why in the world that all of these loners in the world have such serious problems?"
"Why does everyone think that being alone is such a bad thing?"
Conversed: "If I was Lorenzo, I'd stop being such a weirdo and join the heroes already."
The preconceptions that Lorenzo is a freak really start to take a mental toll on him. Things eventually turn into one vicious cycle, as he starts to intentionally avoid others even more, therefore making the others spread the "freak" rumors even more. That's when he pulls a Face-Heel Turn and they still ignored him, so he pulled off a Slasher Smile and decided to kill 'em.
Their "humans are social" belief is so strong that they don't believe anyone could possibly enjoy being alone, and dismiss his claims that he really does enjoy being alone as a transparent case of sour grapes. Jerkasses mock Lorenzo for being a "loser" who "failed at life", while the nicer people out there take pity on him and try to "help" him be more "normal" and sociable so that he can finally have a happy life (much to his annoyance).
The "humans are social" propaganda got into Lorenzo's head making him more depressed to the point of contemplating on killing himself just to escape from the scorn and antagonism of those sociable arseholes.
The "humans are social" propaganda got into Lorenzo's head making him feel that there really is something wrong with him, and as a result, he makes an effort to be "normal". However, he is miserable that way because he hates doing "normal" activities, and he is miserable when alone and doing things he actually likes because he feels like a loser and a freak.