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Nightmare Fuel: DEFCON
A game that is a Defictionalization of the "Global Thermonuclear War" game from WarGames. Watching cities all around the world, possibly even yours, vanish with dry, clinical tallies of the dead is terrifying. "The only winning move is not to play", indeed.
Listen to it with headphones on. This isn't always that bad, but when it happens right as enemy nukes impact Chicago?
By inspecting the file names a number of the ambient sounds become apparent for what they're meant to be. There are both male and female versions of choked coughing, as well as the woman sobbing in despair. Even more disturbing, though, is discovering what sounds like a distorted announcement over a PA system is really the Lord's Prayer.
Oh, and then there's a whole slew of ambient noises which sound like a distorted choir—all of them labeled "souls." You are hearing the cries of souls lost in the nuclear fire—even more terrifying if you already have familiarity with hearing the souls of humanity scream from watching End of Evangelion's Instrumentality sequence.