Ambiguous Disorder

Wil Wheaton: Did [he] just say "Revenge is a dish best served cold" in Klingon?
Stuart: Yeah.
Wil Wheaton: What is wrong with him?
Stuart: Everyone has a different theory...

This character's behaviour is so bizarrely outside the norm that Real Life psychologists would be scrambling for the diagnostic manual to try to figure out what to diagnose them with. It's way beyond mere ordinary quirkiness. No reasons are given for the strange behaviour. No specific diagnosis is ever mentioned in the story. In fact, any resemblance to any real disorder is likely accidental; the character's symptoms are exactly those symptoms the writer wants them to have. It is a case of Ambiguous Disorder.

The disordered behaviour will often be Played for Laughs. This technique is generally used to avoid writing yet another Patient of the Week story about some specific disorder and to focus on the laugh-producing elements without having to deal with the serious issues. Or, less generously, to mock the kooky outer aspects of mental illness without the risk of getting angry letters.

In the instances where this trope is played seriously, the character usually overlaps with The Spock, Pinocchio Syndrome, or Tin Man and focus on this character's struggle to befriend people or otherwise fit into society.

A lot of mentally ill people in classical literature, especially from the 19th century and earlier, tend to be this; psychiatry was a very young field back then (and, until a certain point in history, didn't exist at all), and so there was no manual to turn to if you wanted to give your character odd quirks. Also, the lack of psychiatric expertise during these periods means that many historical figures might have had undiagnosed conditions (endless Wild Mass Guessing exists about this topic). Even today, due to difficulties in pinpointing an exact diagnosis, this is also often Truth in Television. That said, No Real Life Examples, Please! We don't want to start any sessions of "armchair diagnosis," since that kind of speculation about real people inevitably leads to controversy.

Compare The Disease That Shall Not Be Named, Soap Opera Disease, Victorian Novel Disease, and G-Rated Mental Illness.

For when a character is confirmed (either in-story or by Word of God) to be autistic but their portrayal is a bit off; please check Hollywood Autism.


Examples

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    Anime & Manga 
  • Aya from Shibariya Komachi is a Softspoken Sadist, admits he doesn't really have emotions, and feels no sympathy for others. He reveals he has started to feel some emotions due to magical bonding with the others in his group, but othervice just does as he's told. He often will tell facts coldly in dangerous situations if he's safe instead of saving his friends, he often even strangles them from behind for fun.
  • Yuuki Rieko of 14Juicy displays a limited emotional range and seems to have no interest in, or aptitude for, anything but soccer.
  • Area 88, the 2004 TV anime version:
    • Shin Kazama only speaks when absolutely necessary and has a blunted affect. He's socially awkward, as seen with how he interacts with Ryoko in flashbacks. He's aloof and detached from the other pilots at Area 88, and only slightly less so with friends such as Kim and Mickey. He demonstrated this behavior before his time at Area 88, so it can't be attributed to depression or war trauma.
    • Mickey has a somewhat bipolar temperament. He can be cheerful and gregarious in some situations, and extremely angry at other times. He's prone to violence, as demonstrated when he punches Makoto Shinjou in the first episode and beats him within an inch of his life in the last episode. It's not clear if this is Mickey's default personality or a result of his war trauma.
  • Generally Played for Laughs, but the extremely strange behavior of most of the cast of Axis Powers Hetalia coupled with how they've lived through countless years of wars, diseases, and other difficult times makes one wonder.
  • Osaka from Azumanga Daioh thinks in ways so completely different from other people that it's easy to think she might be mentally disabled in some way. She's dreamy and inattentive, prone to weird misunderstandings, has poor motor control, and occasionally seems to suffer from actual hallucinations. But although she seems mentally slow, she gets only slightly below average grades at a regular school and manages to socialize more-or-less normally. She even has some Genius Ditz tendencies: she's prone to penetrating insights that escape all the other characters, she's surprisingly well-versed in some obscure topics like marine biology, and her odd way of looking at the world makes her extremely good at certain kinds of riddles. The joke here — which can easily escape Western viewers — is that Osaka's spacey, laid-back personality makes her a humorous inversion of the stereotypical brash, loudmouthed, Hot-Blooded Idiot From Osaka.
  • Claire Stanfield from Baccano!. There's definitely something off about him, though it's hard to pinpoint exactly what. He's prone to violence but follows a set of rules so completely alien to the average person that he can't really be called "good" or "evil", and can be affable and calm, even while brutally murdering someone. He's even said that he believes the world to be an illusion and everyone to be a dream of his own making, which is often attributed to sociopaths, and thinks of himself as completely invincible (which might even be true, thanks to Achievements in Ignorance).
  • Bakuman。: Eiji Niizuma has extremely odd sitting patterns, demonstrates some trouble with social conventions and nonverbal clues, and has an obsessive interest and talent in a particular subject. Ice Queen Aiko Iwase also qualifies.
  • Edward from Cowboy Bebop is ludicrously intelligent but shows absolutely no ability (or inclination) to socialize in a remotely normal fashion for even brief periods. She almost always skips, cartwheels or dances instead of walking, and she sings improvised songs about whatever she's doing, often as a substitute for normal conversation. Her closest friend is a hyperintelligent, non-talking dog.
  • Death Note:
    • Super-detectives L and Near have several odd tics and habits and a near genius intellect that highly suggest some manner of disorder, though nothing's ever spelled out in the series.
    • Villain Protagonist Light Yagami is also undeniably insane, but it's never clarified where exactly it comes from. Between his monster god complex, inability to cope with any perceived evil, and constant manic laughter, there's something definitely wrong with him; that's all without even discussing the fact that he picks up mass-murder like a new, exciting hobby. For the record, Word of God states that Light went off the deep end was because he was a perfectionist and couldn't reconcile that with the fact that he had unintentionally murdered someone except through Insane Troll Logic.
  • Detective Conan:
    • Hattori Heiji's really thick about other people's feelings, bad at picking up social cues, and extremely awkward a lot of the time. He can't lie without stuttering and giggling like an idiot, and he latches onto ideas or interests and does not let them go. For example, when he first became friends with Conan, he talked about Shinichi SO incessantly that his childhood friend believes him to have a girlfriend in Tokyo with the last name Kudo. He's also extremely adept at remembering little details and noticing anything out of the ordinary, no matter how minor.
    • The protagonist, Shinichi Kudo/Conan: In the first episode, he does not know when to stop rambling on about Holmes and Conan Doyle and talks to Ran about it the entire time they are at the roller coaster. Even whenever he dates her and starts off wanting to tell her his feelings, instead he ends up gabbing about Holmes again. He is not very social and it is implied that many of his teachers and classmates believed him to be arrogant and self-absorbed. Also, he seems to be quite blunt and unaware of social tact.
  • Maria, from A Devil and Her Love Song, is shown to be incredibly blunt, has great difficulty in expressing her feelings, and shows an immense lack of social tact, namely bringing up topics that make other people very uncomfortable or upset and not realizing it. In flashbacks, this is shown to have been normal for her since she was a small child, with her mother worrying that it would cause trouble for her later in life. She shows little restraint when it comes to lashing out at others (she was expelled from her first school for hitting a teacher who didn't take a friend's bullying seriously) but also goes to great lengths for and clearly cares about people close to her. Personal attacks and harassment on her, meanwhile, are generally met with emotionless responses.
  • Ellis in El Cazador de la Bruja is somewhere between this and a Cloudcuckoolander. Possibly explained by her being an Artificial Human.
  • Considering how quirky most of the characters in Eyeshield 21 are, the fact that both Shin and Tetsuma are both considered a little "off" by both the other characters and standards of the series says something:
    • Shin speaks in monotone with textbook level formality, has an encyclopedic knowledge of everything related to physical fitness (he maintains a VERY strict nutrition plan and seems to be very well-read on human anatomy), and absolute devotion to improving himself as a football player. At the same time, he speaks his mind in the most direct way possible (both positively and negatively), has no interpersonal skills or awareness of social norms (he doesn't see anything wrong with walking around shirtless), and is completely oblivious about anything that's not football or school related (when his teammate Sakuraba grows a beard, gets a crew-cut, and starts training harder, the only thing Shin notices is that Sakuraba's muscle tone has improved). Nonetheless, he's very respectful and always means well, so the few friends he has seem to take his many idiosyncrasies in stride.
    • Tetsuma is very literal-minded, even more oblivious to social norms then Shin (as well as being an expert on his position), and can't seem to function normally without his best friend to tell him what to do. When he does speak (which he'll only do if someone specifically tells him to speak), it's very robotic and formal. Most likely because of his difficulty in interacting with people, he dearly treasures his friendship with Kid, who accepts him regardless.
  • Erza Scarlet from Fairy Tail is extremely socially awkward and serious, and holds other people to such high standards that she tends to drive them away. Much of this can be explained by her traumatic childhood and the fact that she hasn't been very well socialized with other people.
  • In Free!, if it weren't Played for Laughs Haruka's obsession with water and swimming, to the point that he once attempts to dive into a fish tank after stripping down to his swimsuit in a pet store, would almost certainly result in someone trying to diagnose him with a disorder. He's also extremely socially awkward, rarely emotes at a normal level, and is very blunt when interacting with others, which isolates him from most of his peers. While he gradually improves his social skills over time at the beginning of the series he's almost entirely dependent on his friend Makoto, who makes sure he actually goes to school and communicates for him.
  • Fruits Basket:
    • Ren has some sort of intense codependency focused on her husband — so much so that years after his death, she remains intensely hostile to the point of extreme emotional abusiveness toward any female character she saw as a rival for his affection, including her own daughter. This seems reflect insecurity over class issues in their relationship — Ren was a lowly maid before the head of the household fell in love with her — but her behavior is so extreme that it's hard to believe she wasn't a bit unhinged even before; at one point, her response to feeling as if her "mind is very clear" is to take a knife and threaten her own child with it, to get back an empty box. The most we're told is that she's "a little sick, mentally and physically", but no specifics are given.
    • Akito shows similar behavior. Intense co-dependency towards the other Zodiacs (to the point of having a complete breakdown at the thought of any of them leaving) just the tip of the iceberg. Akito has also been known to physically and mentally assault anyone who threatens what she considers to be the happy little world the Zodiac all live in. She has no friends outside of the Zodiac, and those relationships are awkward and strained. While more than a little of this is likely the result of Akito's abuse at the hands of Ren, it's also hinted that Akito inherited some sort of mental instability from Ren and/or Akira.
    • Machi seems to have some sort of disorder, too, although it's considerably more subdued than Akito's or Ren's. She has no friends (except her half-brother), dangerously low self-esteem, and trouble communicating with people in general. And then she feels compelled to ruin things when they're too "perfect", either methodically or in fits of violence. Presumably this is because of all the stress and anxiety that she built up trying to be a "perfect child", all compounded when her parents essentially declared her a failure and shifted their affections to her little brother.
  • Shu Ouma from Guilty Crown is an Extreme Doormat with No Social Skills who admits to himself that his mind might be out of step with everyone else's, and has only made "friends" by going along with what other people say. When he makes a carelessly cold remark about someone else and is reprimanded for it, he can only think about his own feelings that were hurt, rather than feeling bad about what he said. He also has trouble with making eye contact with other people.
  • Erio from Ground Control to Psychoelectric Girl is a delusional teenage girl who believes she's an alien who can fly. For the entirety of the first episode she's rolled up in her futon and walks around in it. She has also shown dangerous behavior trying to "prove" she's an alien. Erio was originally an Emotionless Girl and was a hikikomori until Makoto coaxed her out of her shell. Her behavior is due to having gone missing a year prior and having no memory of the six months she was gone. Erio has since become convinced she's an alien.
  • Several protagonists in the Gundam franchise have traits like this. Seems to have something to do with being a Newtype.
    • Amuro Ray of the original Mobile Suit Gundam is capable of social interaction, but absolutely hates it. He's paranoid, prone to focusing on himself, and in his Establishing Character Moment, is shown sitting in his room in his underwear, not having eaten in a day, looking at a computer chip through a microscope and studiously ignoring the evacuation siren blaring outside. His friend Frau specifically states that this isn't uncommon behavior, and that his neighbor was supposed to come in and tell him if the siren was going off.
    • Kamille Bidan of Mobile Suit Zeta Gundam has similar Newtype traits to Amuro in addition to a volatile temper and a near-genius intellect, but is also capable of compassion. Big Bad and sort of Shadow Archetype to Kamille Paptimus Scirocco is similar but has incredible disdain for people and an extreme Lack of Empathy, which he compensates for with his Psychic Powers.
    • Kira Yamato of Mobile Suit Gundam SEED shares many of Amuro's personality traits; the main difference is that he tries to be social (despite sucking at it) while Amuro deliberately avoids other people at all times.
    • Tiffa Adill from After War Gundam X is a Mysterious Waif who in the beginning largely keeps to herself and fixates on creepy drawings she makes to express her emotions, wears loose-fitting clothing that looks like something a girl with sensory integration issues would wear and demonstrates a form of Spider-Sense in additional to more explicitly supernatural Seers abilities. The fact that she herself questions whether she's really a Newtype makes it even more ambiguous.
  • Hime Shirayuki/Cure Princess from Happiness Charge Pretty Cure seems to suffer from sensory overload issues when more than one person tries to speak to her or when she hears loud music. A Running Gag in early episodes is that she usually becomes overwhelmed to the point that she physically flees the room when in these types of situations. She also displays a general lack of knowledge of how to behave in most social situations.
  • Eru Chitanda of Hyouka gets easily distracted and has an outright obsession with mysteries, and isn't able to stop thinking about them until she solves them. It's also implied she may have some sensory integration issues and seems to have much sharper senses than other people.
  • Inside Mari implies this with the original Mari (as opposed to the protagonist-Isao-in-Mari's-body) when Isao tries repeatedly to tell Mari's mother who he really is her reaction is a strained smile and trying to get Isao to take medication. As the manga goes on there are heavy implications that no body swap occurred and Mari has a Split Personality.
  • Sawako from Kimi ni Todoke. At the age of fifteen she's never made a single friend, and frequently misinterprets social cues with hilarious results. She doesn't seem to find this at all weird. Though this is mostly explained by her frightening appearance causing people to avoid her and her resulting social inexperience.
  • Buchi from Mekko Rarekko: Hamamura, his only friend in first grade told him that he's no friend of his. Because of that experience, Buchi has No Social Skills or a very small number of social skills. Buchi goes to extreme lengths to make sure that his friends stay his friends and when it doesn't work he wonders if he did something wrong or if there is something wrong with him. Two good examples are Fukami cutting off his relationship with Buchi after learning that he didn't want to be hated by his friends leaving Buchi wondering why. Then in the sixth issue, Taishou, Buchi's other friend (and only other friend) spends time with someone else and he stops seeing Buchi. Buchi is left extremely lonely and, as mentioned above, wonders if something is wrong with him.
  • Monster:
  • Most of the main Neon Genesis Evangelion cast would probably count - it comes with the Dysfunction Junction nature of the show. Whether they have anything diagnosable, though, is anyone's guess. Their highly traumatic backstories certainly don't help, at any rate.
  • One of the first things the audience learns of Shiro of No Game No Life is that she has a communication disorder. In Japanese parlance, that is a catch-all phrase that covers not only what is strictly the medical definition of the term, such as Speech Impediment, but also such things as social anxiety or autism.
  • The protagonist Tomoko from No Matter How I Look at It, It's You Guys' Fault I'm Not Popular! seems to live this trope. She's extremely socially awkward, to the point of being incapable of talking to anyone who isn't her relative or best friend without stuttering and stumbling over the simplest of words several times. She also seems to view herself as superior to other people for no good reason, often taking anime and manga clichés as her stepping stones to becoming popular but they generally end up failing. While the series is playing it for comedy at times, it gets Played for Drama just as often.
  • In The Pet Girl of Sakurasou, despite Mashiro's behavior, it's never outright stated that she has a mental disorder. The closest thing her dormmates did to name her a disorder was for Sorata to call her "special", having been fed up with her antics earlier that day.
  • Jirarudan/Lawrence III from Pokémon 2000. He's an art collector of a ridiculously high magnitude who seems to have learned social skills by rote, has a narrow and fixed attention span, wears a long coat with an undershirt to tropical islands in the middle of summer, has almost no change in facial expression or vocal intonation despite living by his passions, seems to have difficulty recognizing cues from others, and takes everything, including the legend and Misty screaming at him, only by the words presented without considering tone or alternate meaning.
  • In Pokémon Adventures, Black is so focused on his goals that he needs his Munna to eat his dreams in order to focus on the task at hand. Attempts to do so without clearing his mind causes him to overload his brain and faint. He does eventually get a little better whenever White is concerned, but it still takes a lot of considerable effort. Black also has No Social Skills as a result of being so focused; he isn't inherently a Jerk Ass, but often he honestly just doesn't notice how his actions can inconvenience or hurt others.
  • The Nuns of Princess Jellyfish clearly have something, what with their singular obsessions, various tics, and near-total inability to interact with anyone outside of each other, but this isn't focused on and usually only pops up as a source of comedy.
  • Ami Mizuno/Sailor Mercury from Sailor Moon is incredibly intelligent, but has a hard time making friends or fitting in with kids her own age, and often comes off as cold and unemotional to her peers. This is even more pronounced in the live-action version, where she also displays a complete inability to understand sarcasm, hyperbole, or social cues (which is Played for Drama a few times).
  • Nozomu "Mr. Despair" Itoshiki of Sayonara, Zetsubou-Sensei. Focuses on one topic for an incredible amount of time; depressive and paranoid to a nearly delusional degree (although it's Played for Laughs); is a self-proclaimed master of not looking people in the eye due to a family custom that would force him to marry the first person he makes eye contact with. The rest of his family have their own quirks and likely played a large role in making him the dysfunctional mess he is.
  • Yuki from School-Live! is an eccentric Cloudcuckoolander who acts much younger than her actual age. She is delusional and is oblivious of the Zombie Apocalypse due to Repressed Memories, until being forced to kill a zombie snaps her out of her hallucinations. Miki thinks she has Multiple Personality Disorder however her symptoms don't fit. Even prior to the zombie outbreak she was shown to have been bullied by the other girls due to her personality and looks (she wears a cat-earred Nice Hat and has a kiddie looking backpack).
  • Lain in her initial appearances within Serial Experiments Lain, she shows impairment in the use of nonverbal behaviors, has developed few peer relationships and the ties with two of her friends are very weak, does not show enthusiasm to seek enjoyment or socialization with others, and lacks social or emotional reciprocity. She also rarely speaks, and cannot converse well or start/hold a prolonged conversation. Finally, she becomes unusually enthralled by computer/technological objects and their construction as the series goes on. Never mind the loss of sense of time and space, vivid hallucinations(?), moments of amnesia, hearing voices... All possibly justified from being an Artificial Human. Or the Anthropomorphic Personification of the Internet. Or something.
  • Yutaka from Shounen Note is a highly emotional boy who has sensory issues. Vladmir also has sensitivity to sounds.
  • Saori from Wandering Son is asocial and moody beyond the normal pubescent awkwardness. She's shown to have not have any friends most of her life and goes near hikikomori once. She Cannot Tell a Joke, has terrible social skills, and is awkwardly blunt. When confronted with a friendship issue Saori decides to ruin her 2-year friendships and avoid them.
  • In When Marnie Was There, Anna is frequently noted to act oddly for a child or focus on strange things. The book starts with her acting incredibly detached from other people, enjoying spending time alone, limiting interactions with the family she lives with, and sending postcards to her guardian that are only a few sentences long. She views the world as being a circle with people on the "inside" and on the "outside", believing herself to be on the outside and separate from everyone else. At one point, she goes into a fury over an insult which everyone, even the narrator, considers to be silly. She also doesn't seem to have many friends, but the people she does meet and bond with (Marnie and, later, the family that moves into her house) she's able to form very close ties to. Some of her behavior can be attributed to her fearing that her foster mother is only keeping her for the money, but her reaction to that still comes across as unusual for an upset child.
  • The character Satsuki Yatouji from X1999 is a computer genius and one of the world's most dangerous hackers. In her personal life she mostly avoids contacts with other people (and is frequently annoyed by it) and spends most of her time connected to the supercomputer Beast. She is also extremely rational and seems to have problems with understanding human emotions.

    Comic Books 
  • Marv from Sin City is often considered stupid and insane, an opinion that he shares. He did poorly in school, has No Social Skills, gets "confused" a lot, and often has violent blackouts, although he has mentioned fighting in a war and suffering from symptoms indicative of severe PTSD. In his first story, he mentions that he has always been good at puzzles, implying that he's capable of solving complex mysteries. He was certainly intelligent enough to go up against a powerful crime family. He also cares a lot about his friends and family, is friendly towards complete strangers, and is something of an awkward gentleman with women. On the other hand, he often displays bizarre emotional responses, most prominently a near-sociopathic Lack of Empathy — there have been multiple instances of him remaining genuinely perfectly calm during moments of intense chaotic violence, and he's capable of cool, calculated cruelty and a complete lack of queasiness or discomfort while casually torturing people to death (not that his victims didn't deserve it).
  • At the beginning of The Stupiders we are told that everyone has at least one problem or quirk, but what exactly those problems are is left up to the reader to discern.
  • Every Batman villain, as well as Batman himself in some interpretations. If anything The Joker could probably be diagnosed with "Being The Joker".
  • Cammi from Annihilation and Avengers Arena seems incapable of feeling empathy and has absolutely no verbal filter. Numerous characters remark how incredibly bizarre this behavior is for an 11-year-old girl.
    Nova: Oh, this is Cammi. She says out loud stuff most people just think.
  • Brian of Knights of the Dinner Table. He has a job that involves running an online service from his home (which he is said to not clean) and painting model figurines. He has a savant-like memory of obscure roleplaying game rules, yet sometimes forgets his own phone number. He is stated to become very uncomfortable when any social group exceeds four to six people, especially when it happens away from the context of a shared interest. He rarely speaks unless dealing with gaming, and has a face and body language that is usually unreadable. And finally, some things that would annoy other people seem to have no effect on him at all, while something that others would take in stride can send him into a sudden and brutal fury, typically involving flipping over the gaming table in rage.
  • Runaways
    • Nico is shown to have issues dealing with stress, loss, and rejection. In the first story arc, she mentions having "this thing with stress and eating". Later, after Karolina leaves to marry Xavin, Nico sits in her bedroom, with a pile of her clothes scattered around her. She later notes that she has a tendency to throw herself at "the nearest warm body" when she's upset or confused (kissing Chase after a near-death experience, even though he's dating Gert, reacting to Gert's death by sleeping with Victor, etc.) All of the characters act in different ways to cope with the stress of growing up as the children of supervillains, but Nico is the only one who feels her behavior is unacceptable.
    • Later member Klara talks to plants, is prone to weird moods, and occasionally blurts out appallingly rude things. Whether her behavior is due to her traumatic background, her Fish Out of Temporal Water nature, some sort of neurological issue, or just a consequence of the inconsistent writing that plagued the series in its later arcs has never been explicitly stated, though Avengers Academy hinted that she might have PTSD.
  • It was implied for years that Hank Pym from The Avengers likely had some sort of mental illness, as he displays obsessive behavior, sometimes goes through violent mood swings, and is prone to frequent identity crises. After years of this, Marvel finally dropped the "ambiguous" part and made it canon that Hank suffers from bipolar disorder.
  • Rufus Whedon from Locke & Key. He's definitely "special" in some way, but he seems too articulate for retardation or Downs. His first appearances made him appear to have some sort of disassociative identity disorder (he only talked through his action figures) but later ones had him talk on his own and say that was just pretend.
  • Spinister from Transformers: More than Meets the Eye. He's best described as a mix between an autistic child and violent psychopath. Despite this, he's also an ace surgeon who can defuse bombs and seems to be able to socialize well.
    "The fire's giving me funny looks, Krok. I think I'm gonna shoot it."
  • Sonic from Sonic the Comic. He cannot express his feelings well and back when he was younger he was asocial enough to rely on a human for companionship, instead of other animals. He also seemed to only care for running when younger.
  • Herbie Popnecker from the Herbie comic is extremely uncommunicative, has no interest in social interaction of any kind, usually shows absolutely no visible emotions, and seems utterly indifferent to what other people think of him.
  • Cyclops is introverted to an unhealthy extent: the people he interacts with outside of work can be counted on one hand. This trait is compounded by his difficulty with expressing emotion and extreme dependency on his few close friends- all of which, not coincidentally, are telepathic. Everyone else perceives Cyclops as colder than he actually is.

    Fan Works 
  • The My Little Pony: Friendship Is Magic fanfic Jericho has a case of this which is not played for laughs, but rather for drama. The narrator Jericho has one of these. While his behavior is often kooky and generally silly (like monologing his life aloud), at times he gets downright evil (being mentally unable to comprehend how beating a girl into unconsciousness was wrong). Word of God states Jericho has a real condition, but the author refuses to admit what it is. As such, there's a lot of guessing by the fans as to what condition he really has..
  • John Egbert in Homestuck fanfic Brainbent is the only person in St. Lobaf whose disorder is unclear, though fans speculate that he has schizophrenia.
  • Sai in Second Bloom is not very social, very good at art, loves bright colors, has a lisp and is a little slow, but since this is the shinobi world, they don't identify it.
  • Otacon's portrayal in Stray maintains the Ambiguously Disordered traits he has in canon, but adds a few new symptoms - he's not great with metaphors and figurative language and it's mentioned at one point that he can find facial expressions hard to read.
  • In the Sherlock fanfic Baker School Blitz, while everyone at Baker Boarding House has some sort of mental disorder or disability, since it's a special school for the disabled, no one explicitly comments on the nature of Sherlock's disorder, nor that of his brother, Mycroft.
  • A recurring theme in Gender Confusion, during one arc, is the author attempting to find a credible diagnosis for some of the characters using Zetsu as the resident psychologist. Subverted after a believable conclusion actually is drawn, rather than left ambiguous for the whole story.
  • Caim from Mass Effect Human Revolution is clearly heavily traumatized by his past, but there's no DSM-recognised anxiety disorder that can be staved off by harming others.
  • Ada Linus from The Bombshell is shy, has an adverse reaction to touch and noise, has certain habits she strictly adheres to such as wearing the same clothes for days at a time, and has a difficult time reading emotions and body language as well as idioms, among other things. She also exhibits an extreme fascination with all things technical.
  • Gensokyo 20XX:
    • When Yukari had gone insane, remaining like that for about two stories, she was prone to wandering around, which occasionally involves searching for Ran like a lost pet, screaming at random periods (whether or not that is part of it is left up in the air), going ballistic at a moment's notice (according to Amoridere), rambling, and generally incoherent most of the time. By the time of Gensokyo 20XXV, she seems to have regained her sanity, aside from the bouts of Attention Deficit... Ooh, Shiny!!
    • Reimu has mood swings during the events of 20XXIV and, later in 20XXV, chapter 54, it is revealed she periodically stares into nothing, muttering nonsensically or in what she used to communicate in, along with catatonia. It was also noted that she seemed to have some sort of psychosis, which is made more apparent in chapter 115, where she starts clawing at mirrors, claiming to see messages in them.
  • In the Kill la Kill fanfic titled Second Story Window, its inherently clear Ragyo has some sort of psychosis, said psychosis causing her lash out violently against her children, but we don't know what it is and neither does Satsuki who is narrating. Amoridere did state in the end note that whatever is wrong with Ragyo or Satsuki (who is suffering from a kind of psychosis), when the perspectives are flipped, is anyone's guess.
  • History's Strongest Shinobi: While very competent and of decent intellect, Naruto is hyperactive, has a short attention span, misses obvious social cues at times unless it involves fighting or him getting miamed and/or killed and has an interest in fighting. At one point the narration lampshades this by explaining how his friends honestly think Naruto has a undiagnosed attention disorder.
  • From Kiryuuin Chronicles, we have Ragyou, as a result of her husband's abuse, and it is clear she is suffering from some form of psychosis or delusional disorder, yet she does have moments of clarity, which is clear when she holds Satsuki in her arms for the first time in a long time.
  • A mentally ill Satsuki in Remember seems to have the symptoms of an undiagnosed mood and psychotic disorder. Unfortunately, her disorders are to an extent that she cannot take care of herself and has to live in a mental hospital.
  • Marca from Tom Riddle's Schooldays. It is generally believed that what she has has not even been codified yet at the time of the story.
  • An interesting variant occurs in Train Tracks with Ryuuko "Maggie" Kiryuuin. According to Rei's narration as she describes her, the aforementioned seemed to have been a tad developmentally delayed, as she didn't really start walking until she was roughly two and half years old, yet, otherwise, intellect and behavior-wise, she was normal. However, when Rei introduced her, she also noted that the aforementioned wasn't born healthy.
  • The Pandora Hearts fanfic Beyond The Winding Road plays with this a bit in-universe. Lewis' parents took him to many, many psychologists and psychiatrists as a child, trying to figure out exactly what was going on with him. Word of God says they eventually concluded he had Dissociative Identity Disorder, but his mother Beatrix eventually realized that there was more to it. His 'episodes' turn out to be a symptom of his reemerging past memories.
  • Luna from Friendship is Witchcraft is an exaggerated stereotype of awkward fangirls, has little care for personal space, and has No Social Skills.
  • Satsuki in The Mysterious Lady Kiryuuin is implied to have some kind of a disorder, likely one relating to social anxiety, considering that she is so painfully shy and seems to have some agoraphobic traits, considering that going outside scares or, to a lesser degree, upset her. There's also the fact that she doesn't interact with her new house-guests directly and her mother's ghost described her as "fragile in mind", along with having been like that since she was a child. However, while her condition is, to some extent, debilitating, it doesn't keep her from being a caregiver to her younger sister, Ryuuko, and a child she adopted, Nui.

    Films — Animation 
  • Lilo in Lilo & Stitch has a bad case of All of the Other Reindeer, but unlike many examples of that trope, she really is a genuinely strange little person who weirds out her "friends" with a strange mix of eccentricities, behavioral issues, social inappropriateness, and unusual interests. She may have the behavioral and social issues though because of her parents sudden death in a car accident, as well as the stress of possibly being split up from her older sister by social services.
  • White from Tekkonkinkreet: there's definitely something mentally different about him, but it's impossible to distinctly tell what. He's exceedingly childish for his age, refusing to bathe unless prompted and unable to tie his own shoes at age ten. Yet at the same time White has a... ''vivid'' imagination and occasionally a strange, almost cosmic insight.

    Films — Live-Action 
  • In Assassination Games, Brazil has no emotional affect, is obsessed with maintaining his house in perfect order, doesn't seem to get sexual gestures, and has a fascination with using bizarre and archaic weapons in his kills.
  • In The Big Short, Michael Burry is a Bunny-Ears Lawyer who gos to the office in shorts, T-shirts, and barefoot, is constantly drumming to heavy metal, and readily admits that he has trouble interacting with his co-workers and investors, is awkward in one-on-one interactions with his employees, and met his wife on match.com. He believes that this is all due to him having to wear a glass eye after a childhood illness.
  • Miss G from Cracks certainly has some form of disorder. Possibly agoraphobia as she seems nervous during her trip to town and becomes almost panicked when she attracts the attention of some local louts.
  • Damsels In Distress. When Violet was a girl, she would perform various actions in an obsessive-compulsive manner, starting all over again if she couldn't do them right ten times in a row.
  • Pollux Troy in Face/Off is said to have a high IQ, but also has an unspecified mental disorder and screws up simple tasks. He's said to take Mylax, which in real life is the name of a few different medications, none of which are for the mentally ill.
  • Jenny from Famine. She's clumsy and twitchy, yells at random during conversations, goes on profanity-laced rants, her people skills are sketchy at best, and her demeanor (horrified to nonchalant, or hateful to loving in the blink of an eye) jumps all over the place, to the point that a teacher wonders if she is a junkie or suffering from some kind of premature PMS. Oh, and there are bits like this:
    Ms. Vickers: Yeah, Nick just isn't man enough, is he?
    Jenny: Nick is a man! He came on my face!
  • Ghostbusters (1984): Egon is very socially awkward, has quirky and specific interests ("I collect spores, molds, and fungus"), speaks largely in a monotone voice, seems to have a rather short temper that results in violent outbursts when he's agitated enough ("YOUR MOTHER!") and almost never smiles. In the same vein, Ray's speech patterns can be a bit awkward, he can apparently repair a massively ruined car in less than 24 hours, his behavior is very childish and immature, he also fixates strongly on specific interests (the paranormal), and he frequently speaks with his hands while talking.
  • Benjamin Braddock from The Graduate and Harold Chasen from Harold and Maude are both young misfits with little social ability and little motivation to take part in society, largely due to the overbearing presences of the adults in their lives. Benjamin is somewhat well-adjusted - he was an outstanding student and athletenote , and his parents and their friends all adore him. He still has no friends and no idea what he wants to do with his life - after all, he prefers lying in his parents' swimming pool to going out into the Real World™. Harold, unlike Benjamin, actively resists interaction with other people. For example, he enjoys horrifying girls with fake suicide attempts whenever his mother sets him up on a date. (He torments his mother with fake suicide attempts too, but she's used to it.)
  • Ashburn from The Heat probably has something, given how Literal-Minded and obsessive she is. Might be because she was a foster kid and by implication wasn't well socialized growing up.
  • Martian Child: The titular character is a young boy who doesn't understand facial expressions (he takes pictures of other people's facial expressions to try and puzzle them out at his leisure) and has multiple sensory issues (he wears a weight belt all the time to keep from "floating away", is overly fond of seat belts, and can't stand sunlight). He also displays signs of having Synesthesia.
  • Napoleon Dynamite: Napoleon, Kip, Pedro and Deb all display really, really severe social awkwardness and fixations on various unusual subjects (e.g. ligers).
  • The Omen (2006): Damien's supposed to be the son of the devil but if you take the "It was all a coincidence and not supernatural forces at work..." he's just a really weird kid.
  • The Other Woman features William who is either just a very bright boy trying to deal with divorce in the family or a case of this trope.
  • π: Max Cohen is never diagnosed, but he suffers from intensive social withdrawal, obsessive compulsiveness, chronic migraines, psychotic episodes, and possesses savant-like abilities in regards to mathematics (performing division on par with a pocket calculator).
  • Séance: A character is antisocial and awkward, and takes an unnamed medication that he claims is supposed to make him "normal".
  • Sherlock Holmes: Robert Downey Jr.'s portrayal in the 2009 film and its 2011 sequel was more socially challenged than usual, had some weird eye contact moments, and was implied to have issues with sensory integration. This is actually more accurate to the original stories by Conan Doyle than most portrayals of the character (see below under "Literature").
  • Denny in The Room seems completely ignorant of social norms and generally acts much younger than his apparent age, at one point leaping into bed with Johnny and Lisa as they are about to have sex. In an interview, director Tommy Wiseau admitted that Denny is "retarded, a little bit," but he failed to tell the actor that or spell it out in the script, so the performance is confused.
  • The Social Network: Zuckerberg. He cannot hold down a single topic in a conversation. He shows very little tact as well, as an offhand comment he makes to his girlfriend causes her to break up with him. In short, he is much more at home with his computers and code than he is with other human beings.
  • In Spiral, Mason avoids eye contact, goes on manic bouts of obsession with painting a particular set of poses, frequently hallucinates a dead blond girl, and is either killing his models, imagining them and their deaths, or a little of both.
  • There have been numerous articles speculating about Anakin Skywalker and trying to form a diagnosis based on the symptoms he shows in the Star Wars prequels. Likewise, in The Force Awakens, his successor and grandson Kylo Ren shows a similar collection of huge mood swings, extreme outbursts of anger, lack of empathy, difficulties with interpersonal relationships, emotional disturbances, and odd obsessions and anxieties.
  • It stands to reason that most of the cast of Sucker Punch aren't All There upstairs, seeing as they're in a mental institution, but no actual diagnostics are given on their conditions (possibly justified in that it's the 1950s). There's also Blue, who seems to have something wrong with him. He acts like he's just as powerful in the real world as he is in the brothel fantasy, even though he's clearly just an orderly. He continuously declares himself to be the one in charge, completely loses his mind when he realizes that he can't make Babydoll return to consciousness, after her lobotomy, and tries to order the police into letting him go, even though they're there on the orders of Dr. Gorski (Blue's superior) and they clearly saw him trying to molest Babydoll.
  • Garth from Wayne's World. His speech is stilted, he doesn't eat anything that isn't brightly coloured and fruity (to the point of eating a jelly donut with a straw), goes off on some extremely bizarre tangents in conversations, and spends hours obsessing over strange mechanical gadgets.
  • The Wizard: Jimmy, by way of The Rainman with the way he plays video games. Seems to be trauma related, as it began when his sister died.

    Literature 
  • In Dragon Bones, Ward's mother is drugged with some fantasy drug almost all the time, but never acts sober, anyway. She sometimes hums, sometimes babbles nonsense, sometimes says something correct, that could tipp off others about facts she knows about but they don't. As it is a medieval fantasy setting, no diagnosis is ever mentioned, but her children seem to think it is self-induced, and are bitter about it.
  • Ignatius J. Reilly from A Confederacy of Dunces. He's a hoarder, a massive conspiracy theorist, and an extreme luddite and creature of habit.
  • Lisbeth Salander of The Millennium Trilogy. She exhibits several oddities, including Photographic Memory, extremely selective interests (mathematics and computer hacking), and very few changes in expression or vocal tone. The author said he envisioned her as somebody who has turned into "somewhat of a sociopath" from incredibly traumatic experiences, or how a modern-day Pippi Longstocking might turn out after growing up as an mentally odd orphan handled by the somewhat infamous Swedish bureaucratic system.
  • No clear diagnosis for Matt is ever given in Peter Pays Tribute. He carries a bottle of Febreeze with him to public restaurants for fun, apparently.
  • In the book Changeling by Delia Sherman, it's strongly implied that Changeling has been diagnosed with something, but it's never stated what.
  • Colin from An Abundance of Katherines — his social skills are a mess. His only real friend in high school actually needs to tell him when his conversation topics are boring. They become friends after he thinks it is funny to refer to his eye as a "pupillary sphincter." His friend, who was home-schooled up until that point, remarks something along the lines of, "I've only been in public school for 2 days, and I know that your sphincter is not something you talk about."
  • In Peter F. Hamilton's The Dreaming Void, implants giving people their own built-in "heads-up display" are ubiquitous, but only Troblum is described as having or needing a "protocol behaviour program" to prompt him through ordinary social situations. He's got an obsessive interest in a thousand-years-past war (that just so happens to be the subject of the two previous books set in that universe) and is explicitly stated to have no real ties to anyone in the Commonwealth.
  • Sherlock Holmes as portrayed by Sir Arthur Conan Doyle. Later depictions of the character can differ, but the original stories make it fairly clear that it's not just that Holmes is incredibly smart — his brain works in a different way from most people. He's got a hefty dose of social awkwardness and assorted weird behavioral quirks to go along with the extreme intelligence and perspicacity, as well. And then there's the cocaine addiction.
  • Daymar the wizard from the Dragaera books is truly brilliant, but also extremely Literal-Minded, and oblivious to social cues unless they're explicitly spelled out — and after they are explicitly spelled out, he never shows even a trace of embarrassment about how awkward his own behavior was.
  • Charlie in The Perks of Being a Wallflower is a more serious example of this. He was held back for being "emotionally damaged", but the disorder is never named. He seems to have trouble in social situations and seems to be very sheltered from normal life.
  • Jay in the Spaceforce series is clearly not quite normal by the standards of his own species, the Taysans, and perhaps even by human standards. His commander Salthar describes him as a 'sociopath', but this seems to be because, unlike most Taysans, he's adept at lying and has no shame when it comes to pursuing sexual liaisons. However, despite his ruthlessness and tendency to be a Manipulative Bastard, he is capable of feeling love and loyalty.
  • Bella from Twilight. By her own admission, she has trouble connecting with people in general. Apparently her only friend in Phoenix was her mother, who she still forgets to write to when in Forks. She becomes extremely obsessed with things like becoming a vampire, while making no plans for things like college or a career. She becomes so unhealthily obsessed with Edward that when he leaves her, she first is catatonic and then makes no effort to move on with her life, instead choosing to spend her college money on motorcycles and nearly killing herself cliff diving. She gives very little thought to the consequences of her actions, and tends to not understand why people react the way they do.
  • The narrator of Oh, the Humanity!: A Gentle Guide to Social Interaction for the Feeble Young Introvert has a pretty spectacular one, mixed with generous doses of denial and Know-Nothing Know-It-All. Traits include an obsession with germs, total disinterest in other people's lives ("I meant to call you to tell you you have so much to live for...I'm sorry, I've just been doing so much gardening lately"), a grasp on human interaction that can at best be called fumble-fingered, an inability to focus or prioritize (at one point delaying a pub crawl for two hours because he forgot to give his parakeet its ear medication, and didn't like to wake it up), and massive, hubristic pride in the social skills he does not in fact possess. It's unclear how much of this emerged from his Hilariously Abusive Childhood.
  • A side story in The Dresden Files, told from Murphy's point of view, makes Harry Dresden an in-universe example of this: From most Muggles' viewpoint, Dresden, a self-declared wizard, has a tendency to poke around crime scenes, looking or asking for things like toenail clippings or hair straws, mumbling to himself and never looking people in the eyes. In addition to this is his at-times-dubious personal hygiene, Man Child personality, near-pathological need to snark at and gainsay authority figures, and Nerves of Steel that make it unnerving when he seldom shows outwards reactions to things normal people would lose their wits over. The end result is that it makes him seem, at best, a high-functioning but very eccentric autistic. By reading most of the books (which are from Harry's point of view), most of these behavior patterns are explained logically, but that doesn't make him seem any less weird to the muggles he must uphold The Masquerade to.
  • Gracie Milne, a minor character in Tipping the Velvet, is a bit like this. She doesn't really have any identifiable symptoms, but she's definitely more than a little odd, acts rather young for her age, and she may have sensory processing differences considering her fixation with colors.
  • Diary of a Wimpy Kid:
    • Fregley has no friends and is blissfully unaware that his bizarre behavior disgusts others. He's a more negative portrayal, with his social deviations shown as weird and repulsive. This could be a case of Unreliable Narrator, since Greg Heffley (the narrator) is just a kid and probably doesn't know much about any disorders that Fregley might have. His repulsiveness in Greg's eyes could just be due to a lack of understanding.
  • Harry Potter:
    • Luna Lovegood could have some kind of personality disorder, probably because of her upbringing under her eccentric father Xenophilius (who himself is an odd duck) combined with witnessing her mother's death and being socially isolated for her outlandish ideas. However, she's a very wise girl with a strong sense of empathy and understanding of people, especially Harry.
    • The books heavily imply that pre-Voldemort Tom Riddle was a sociopath, but it's never directly stated what precisely is wrong with him. He sees absolutely no value in forming relationships with others unless there is some benefit in it for him, he is completely incapable of feeling love in any capacity, he enjoys working alone and refuses to confide in any of his "friends", he is disturbingly good at understanding how to manipulate people into doing what he wants, and can kill anyone, from babies to his own remaining family, without any hint of remorse.
    • Harry himself also shows symptoms of PTSD during book five.
    • Severus Snape is a genius when it comes to magic; he exhibits a narrow, intense interest in magical studies and, as a preteen during his first year at Hogwarts, knew more about dark magic than most seventh-years did. But on the flip side, he's twitchy, reclusive, lacking in social graces, and generally creepy and off-putting.
  • Discworld
    • Jeremy Clockson in Thief of Time, who has No Social Skills and becomes agitated to the point of violence when confronted with inaccurate timekeeping. He also has medicine, so presumably he has been diagnosed with something, but we never learn what (and this being Discworld, where No Sense of Humor is Nichtlachen-Keinwortz Syndrome, it's unlikely the diagnosis was anything a Roundworld psychologist would recognize).
    • Stanley Howler from Going Postal is profoundly awkward, slightly neurotic, and obsessed with two things, pins (and later stamps) and the Rules and Regulations of the Post Office: "The world of pins was simple, but everything else was very complicated and only worked if you followed the rules". He's also prone to occasionally-violent meltdowns (which Mr. Groat refers to as Stanley's "Little Moments").
  • Fifty Shades of Grey:
    • Anastasia Steele is extremely thin, has a poor self-esteem and body-image and never wants to eat.
    • Christian Grey, who by his own admission is "fifty shades of fucked up". He dislikes interacting with others, save for a small circle of people he's close to. He seems to have difficulty with communications, often getting angry with Ana for not knowing something she couldn't know unless he told her. He has extreme issues with impulsive behavior, immediately responding to a joke e-mail Ana sent by driving to her house, tying her to the bed, and forcing himself on her, without giving her a chance to explain the situation. He also seems unable to rationally think about previous situations (for example, he continues to hate blondes because a blonde police officer took him away from his dead mother's body, even though sixteen or so years have passed and he should be able to think about it differently). Oh, and he enjoys taking submissives who look like his "crack whore" mother (his own nickname for her), because he enjoys pretending he's beating her. He blames this behavior all on childhood trauma even though said trauma ended when he was four and, by his own admittance, he doesn't remember much of it.
  • Handled fairly realistically in the works of H.P. Lovecraft. Several of his stories involve characters going insane but never clearly diagnosing them. Part of this can be attributed to the fact that psychological terminology was not as mainstream when he was writing. It can also be justified by the fact that some of his characters may be suffering from mental conditions that even modern psychology wouldn't be able to clearly place (any "official" diagnosis being an approximation), especially given that most of his "insane" characters became such as a result of seeing horrors beyond their comprehension.
  • Bradley Chalkers from There's a Boy in the Girls' Bathroom clearly has some kind of behavioral/conduct disorder-he bullies people, performs poorly in class, has almost no friends, displays odd behaviors like cutting paper into tiny pieces-but it's never specified.
  • In Hush, Hush, Nora generally cannot/will not remember traumatic events that happened to her (such as Jules trying to kill her, or someone drugging and chasing her). She is obsessed with her boyfriend and whether or not he's cheating on her, and is incredibly concerned about him leaving her even before he shows any indication that he'd do so.
  • Brandon from The Leonard Regime acts very strangely. Some his thoughts and acts are outright ridiculous, and nobody knows why he does it.
  • The title character's sister from Raptor Red, though not human, is clearly stated to not think or act like a normal raptor. She has terrible fits of temper, doesn't think logically, and is so highly aggressive that she can't stand the company of other raptors (they're normally a social species). It's possible she has some form of dinosaurian psychosis.
  • The titular character from The Body Of Christopher Creed, from his description, is terrible at picking up on social cues, seems to have a slight Self-Serving Memory, speaks in Antiquated Linguistics, and obsesses over random subjects like Eastern religions and lead poisoning.
  • Bigend Books: Main character Cayce has a panic reaction to brand logos that's downright pathological, needs verbal stimming, and considers herself someone who doesn't have hobbies — she has "obsessions", worlds to retreat into.
  • In One Flew Over the Cuckoo's Nest, of all the main characters in the institution, no one has an explicitly given mental illness that puts them there, putting it all up to speculation.
  • The Mahabharata character Mayaa is an unparalleled architect who unconsciously vocalizes his thoughts, obsesses over work to insomniac degrees, and rarely speaks to even his coworkers. When one of Mayaa's creations is destroyed, he falls into the sort of deep depression most people reserve for human deaths.
  • Joe Pickett: Wyatt, the youngest of the Scarlett brothers in In Plain Sight, is generally regarded as 'odd' and 'not quite right' without any specific diagnosis being offered.
  • Barnaby Gold, the eponymous central character of The Undertaker series, is generally regarded as 'not right up top'; being cold and emotionally detached and not having normal emotional responses to events like his father's death.

     Live-Action TV 
  • Coronation Street has Roy Cropper, who is simply seen as odd by his neighbours with his bizarre lectures on really trivial subjects, fascination with details, and that little bag he carries everywhere.
  • CSI: Gil Grissom. His level of social understanding fluctuates between episodes, along with his attention to trivial details and love of bugs.
  • Law & Order: Criminal Intent: Detective Robert Goren; it's suggested he simply never learned proper social skills growing up because his family suffered from one mental illness or another. Goren is what happens when the genetic dice are loaded to roll Snake-Eyes and come up Lucky 7 anyway.
  • The Big Bang Theory:
    • Sheldon is socially challenged, has fairly monotonous speech, and exhibits heavily ritualized behavior.note  He even has hypersensitive hearing; the others refer to it as "Vulcan hearing" and are usually cursing it due to his overhearing things they wish he didn't. He also shows a disturbing lack of empathy, obsessive behavior, and an unusual number of phobias.
    • Leonard rather noticeably struggles with keeping eye contact in a conversation and fidgets with his fingers constantly. Besides Raj (who is unable to speak in front of a girl) he is the one with the most trouble actually trying to communicate in an unfamiliar social environment. Unusual for this trope, these things are downplayed as the series progressed, factoring a lot of his issues into his low self-esteem at the beginning and showing a great deal of personal growth.
    • Raj was shown to be almost biologically unable to to speak in front of a woman without some sort of anti-anxiety medication or alcohol to calm his nerves. This ended up actually being, well, diagnosed in the second season by Leonard's mother as selective mutism.
    • Sheldon's Distaff Counterpart Amy Farrah Fowler shows many of the same symptoms, but later given a twist that makes her further removed from being a female Sheldon. Some of her oddity stems from the show playing her demi-sexuality for laughs.
    • Before Amy was introduced, fans saw Leonard's mom as a "female Sheldon". She's cold, detached (to the point she's only ever had sex to procreate and Leonard was forced to build a hugging machine that his dad borrowed) has no problem with treating her son as a test subject and embarrassing him (despite, ironically, studying and understanding human behavior is her job, which also makes this a case of The Cobbler's Children Have No Shoes), and several weird Sheldon-esque traits such as demanding her coffee be made a certain impossibly specific way and announcing "I have to urinate" every time she gets up to go to the bathroom. From dialogue, it's clear her mother deliberately held her back from socializing with other children when she was growing up.
  • Community: Abed is incredibly fascinated with films and television and is a bit obsessed with projecting their tropes onto real life. He has a strange, somewhat sterile demeanor, doesn't seem to know (or even when corrected, care about) how to go about certain social situations, and is face-blind. He also becomes highly distressed whenever anyone tries to tamper with his life as he's familiar with it (such as messing with the engine of his Dreamatorium or moving clocks an hour back). Whenever he's about to have a meltdown he lets out a high-pitched whine. Lampshaded on numerous occasions, either by the story (in "Advanced Dungeons and Dragons" he is referred to as "Abed The Undiagnosable"), other characters and himself (in the pilot he rattles off everything he knows about Britta from their one conversation including that she has a brother who "works with children with a disorder I might want to look up"). During the Musical Episode, in one of the songs he sings, "On the spectrum? None of your business.", apparently to the audience.
  • While not being exactly there at all, Taxi's Jim Ignatowski often forgets about people, he lived for five years in a condemned building and he once pestered Alex to the point of harassment for not watching E.T. the Extra-Terrestrial. He's also an Hero-Worshipper of Louie, who ostensibly treats him like crap.
  • It's Always Sunny in Philadelphia:
    • The episode "Sweet Dee Is Dating A Retarded Person" revolves around this trope, with Dee dating a rapper named Lil' Kevin, who acts much younger than his age, displays odd hand tics, and is incredibly strong, all of which Dee to believe that he is mentally disabled. However, at the very end of the episode, it turns out that he isn't, he's simply very eccentric.
    • A whole book could be written on Charlie. He displays dyslexic tendencies and can't read, is a musical savant (he is able to masterfully play a keyboard despite having absolutely no formal training, and claims "Keyboards just make sense"), displays almost superhuman strength at times, displays unhealthy fixations on his love interests, and seems to have an impossibly high threshold for pain.
  • Spinelli, on General Hospital, nicknames everyone and uses unnecessarily long words... but when Dr. Matt Hunter suggests undergoing tests for autism, he refuses, saying "I am me".
  • Reginald Barclay from Star Trek: The Next Generation shows severe social anxiety, along with an obsessive streak and a compulsive tendency to retreat into fantasy.
  • Buffy the Vampire Slayer:
    • Anya — at first viewers are led to believe her complete lack of social skills is a result of having been a demon for centuries, but eventually it's revealed that she acted exactly the same before she became a demon.
    • Andrew also shows a fair degree of social ineptness, sometimes flat affect, and a fascination with certain topics that leads him to recite in detail at times.
    • Spike managed to improve his social skills over the course of a century, but he has a mixed bag of vaguely bipolar, obsessive, borderline and schizoidal tendencies which come and go with the story. Whenever he's bored, he'll do something ridiculously suicidal just for the hell of it, he stalked Buffy for over a year, and once had a full-blown psychotic episode.
  • Michael Scott of The OfficeNo Social Skills, near-total inability to understand metaphors, sarcasm or hyperbole, savant-like skills in regards to sales, very strong indications that he has never had any friends, and overall behavior that no normal person would believe was acceptable. This pops up in a lot of Steve Carell roles.
  • Cal Lightman of Lie to Me. Quite socially uncomfortable, with a very fixated interest on lies and facial expressions as well as psychology. He destroyed his own marriage because he couldn't switch off.
  • Fringe: Dr. Walter Bishop started like this, but this is jossed in a Cerebus Retcon where Walter got William Bell to perform brain surgery on him to stop him becoming evil like Walternate. All indications are he was already an emotionally distant genius before the elective brain surgery, though.
  • Bernard Black of Black Books. Very socially awkward and uncomfortable with changes in an extremely repetitive routine. Also has an extreme Lack of Empathy, enjoys the suffering of others, and honestly doesn't seem to understand that having his book shop sell books and make money is a good thing (he's infuriated when Manny sells his stock, because it would mean a minute long phone call to his supplier). Also The Alcoholic, which probably exacerbates things. When Manny leaves, he is so unable to take care of himself that it nearly kills him.
  • NCIS: Lab Rat Abby Sciuto. She is very good at what she does and shows a childlike sense of joy while working, she will often give long-winded and highly technical speeches when explaining something, she is extremely attached to and protective of those she cares about, and she becomes almost unable to function both professionally and personally if she has to dress in anything other than her typical goth style or can't listen to her music while working.
  • Chloe O'Brien of 24. It's not mentioned as any sort of possible mental illness in the show; other characters just vaguely refer to her as having an odd personality. She is often blunt to the point of rudeness, easily irritated, especially when she is in the middle of something, and is generally dismissive of other people. She is, however, not without empathy. She usually isn't aware she's engaging in behavior most would find odd or annoying until she notices the way people are looking at her. It's just that most of the time, she doesn't care. Unfortunately, the writers clearly felt that Chloe could only accommodate one character trait at a time, as in Season 9 her Disorder is replaced by being an emo. Most of her behavioral issues magically disappear, however it could be argued that this is a result of the death of her husband and child.
  • RO from Sea Patrol has a very black and white view of the world, and when asked if this was true he responded "I'm not racist." Then there's his believing Bomber fancied him after she gave him a peck on the cheek, and him not wanting to take credit for saving her life because she told him not to go near her.
  • Renfield Turnbull from Due South is just odd, even compared with Bunny Ears Mountie extraordinaire Benton Fraser. Some fans have wondered how someone with his apparent emotional volatility and clumsiness ever made it into law enforcement.
  • In Raw Philip displays poor social skills, is incredibly awkward at making small talk, likes to keep orderly lists and cooking is his big obsession.
  • Leon from Tucker is obsessed with Mexican wrestling and sea creatures (even sponsoring an octopus) and has a strange collection of human hair.
  • Brick Heck on The Middle. He has the Verbal Tic of, at least once each episode, repeating what he just said in a whisper while looking downward. He's in a special social skills class at his school. He is obsessive about reading almost continually, to the point that he's delighted to get a toy robot for his birthday... because the instructions are in different languages, and he hopes to learn Japanese that way.
  • Saga Norén of Bron|Broen has No Social Skills to an extreme degree, is shockingly lacking in apparent empathy and compassion, and has an extremely rule-bound attitude to life. The actor and creators have said that she probably is somewhere on the autistic spectrum, but that they deliberately didn't state it explicitly or work from a list of recognized symptoms because they wanted to write her as they wished without misleading or offending people.
  • Jerry, Elaine and George of Seinfeld. Complete Lack of Empathy, constant selfishness, unthinking cruelty, continual rejection of any maturity or adult responsibility, and meticulous adherence to a (often fabricated) social code not because they care about others but because it is expected of them. Surprisingly, Kramer is rarely presented as anything other than a regular person who just has a lot of quirks and a wild imagination, while the other three are sociopaths Played for Laughs.
  • Father Ted:
    • Ted is supposed to be the most levelheaded, but is a chronic liar, willing to break laws to achieve his means, and dreams of completely unrealistic things. Bishop Brennan is the only character who can see Ted for what he really is, which is why they mutually hate each other. The creators have noted they were inspired by Seinfeld and it really shows with him.
    • Mrs Doyle has some very odd quirks that suggest she is hiding something about her life (not even the main characters know her first name, for example). The most glaring of these is the fact she wants people to forget she was ever married.
    • Tom, who likes to boast of being a psychopathic killer, but is always friendly to people.
  • In a flash forward on Roseanne we see Jackie take an adult DJ to a psychologist. He expresses little emotion, has a monotone speech pattern, and is fixated on how Becky has changed.
  • Person of Interest:
    • In "Masquerade," Finch seems to have a panic attack while taking the dog out for a walk, but it's not confirmed what exactly caused this. Seeing how this happened after Root kidnapped him, it's possible that the trauma of the ordeal may have affected Finch substantially.
    • Root herself. She was initially believed to be a sociopath, but she denied it, and has shown that she is far too capable of regret, love, and fear to be one. A psychologist once thought she was a paranoid schizophrenic, but that's because he didn't know that she wasn't imagining the hitman coming to kill her or the Machine that was talking to her. The basic consensus from everyone seems to be that she's just plain crazy, but there's no exact indication as to why.
      Finch: [When he realizes Root plans to steal a cop car] Are you out of your mind?
      Root: Since when is that relevant?
    • Shaw shows all the classic signs of sociopathy (lack of empathy, rational reasoning, and deadened emotions), but she is never explicitly called a sociopath. Flashbacks show that despite her skill as a doctor, it was politely recommended that she leave the profession because her horrific bedside manner meant that no one trusted her. She became a government assassin instead, which worked pretty well until her partner was killed for asking too many questions. She has, however, shown the ability to connect with people with difficulty; she has a soft spot for children and dogs, and tends to bond with her coworkers over time as long as they're the type of people she can discuss weapons with. She even gets quite a bit of Les Yay with post-Heel–Faith Turn Root.
  • Christopher Moltisanti in The Sopranos, who has emotional outbursts, fits of alternating aggression and depression, and serious attention deficit difficulties. He self-medicates through drug abuse. His various undiagnosed mental problems are brought up by other characters on multiple occasions.
  • Occurs in-universe in an episode of 30 Rock, when Pete and the writers become concerned that Jenna might be a sociopath, when she passes this supposed test. At the end of the episode, she shows that she's capable of empathy and it's concluded that she's not a sociopath, just highly narcissistic.
  • Timothy Spall, who plays Lord Emsworh in Blandings, said of the character, "Nowadays he'd be diagnosed with some kind of condition."
  • Power Rangers RPM: Dr. K has absolutely No Social Skills, while Gem and Gemma have the mentality of five-year-olds and an inordinate fondness for explosives, yet all three are technical geniuses. Fans tend to blame their issues on the fact that they were denied normal childhoods: a government think tank abducted them and nurtured their scientific gifts at the expense of everything else.
  • Power Rangers S.P.D., Bridge is a Cloudcuckoolander who has a tendency to ramble and make odd, if usually accurate, statements.
  • Supernatural: The angel Castiel has a lot of vaguely related traits: literal mindedness, limited interpersonal skills, No Sense of Humor, and schizoidal tendencies which he attributes to not having spent much time on Earth, even though none of the other angels (including a number who have spent less time on Earth) have any of his problems. Before the civil war, he seems to have been fairly well-liked and to have had a good relationship with his angelic siblings, so his quirkiness probably hasn't caused him any real problems.
  • Cat Valentine, the red-haired Genki Girl from Victorious goes a little beyond normal CloudCuckooLander-ness and sometimes acts strangely eccentric. Sometimes she even knows what she is saying and is a bit ditzy.
  • Game of Thrones:
    • Viserys exhibits a range of bipolar-like tendencies, among other things. First, there's all his mood swings which range from intense calmness to manic twitchiness. There's also his uncontrollable rages, bouts of depression, and extreme self-delusion. His sister Daenerys says that the worst of it only started after they were forced to sell their deceased mother's crown to survive, but considering he's the son of "Mad King" Aerys Targaryen and there's an in-universe saying that the Gods flip a coin when a Targaryen is born as to whether they'll be destined for "insanity or greatness" this makes sense, and centuries of incest probably haven't helped.
    • Daenerys shows no emotion while watching her brother be killed via molten gold to the head, and later unflinchingly ties the woman who killed her son to Khal Drogo's funeral pyre. From there on, she's shown as being extremely focused on her goals, occasionally to the point of foolishness (for example, badgering merchants for ships, without considering that she has no way to pay for them). While she certainly shows more empathy for those in her care than Viserys did, including putting her own goals in jeopardy for the sake of freeing slaves on several occasions, she also is shown to be capable of violently dealing with anyone who tries to hinder her without showing any signs of being bothered. A major source of dramatic tension with her character is what side of the coin for the Targaryens she'll end up being.
    • Joffrey, a product of incest himself, displays a disturbing fondness for violence. At times he even seems to be sexually aroused by it. He shows no signs of empathy whatsoever, is extremely impulsive (ordering a crowd of peasants slaughtered because someone threw a cow pie at him), and derives joy from inflicting random cruelty on others. It's difficult to pinpoint exactly what's wrong with him, but whatever it is it's bad.
  • Merlin:
    • Merlin would appear to have this. He has to make up increasingly bizarre explanations that are maybe just plausible to deflect suspicion, but earn him many a weird look. Arthur alone thinks he is a cross-dressing woodworm-obsessed pathological snarker who can barely function as a keeper of cleanliness. Justified when nobody points this out often since this is nearly a thousand years before anyone began seriously diagnosing mental disorders.
    • By the end of the series, Merlin has ceased caring about anything that's not Arthur, to the point of wild mood swings, irrational and irritable behavior, and selling out his people. Many have called his behavior obsessive.
    • Morgana and Uther seem to share some deeply rooted tendency towards madness. Even Arthur shows some signs of it sometimes. In one deleted scene, Arthur mentions that his grandfather went mad as well, and Merlin points out that these things tend to run in families.
  • The Home and Away villain Angie Russell seemed to become increasingly obviously manic as her tenure went on. Despite having a relatively successful career as a teacher, she had an odd habit of seducing her son's friends if they were mean to him and her method of getting a promotion was to lock the other candidate up to try and bring on an OCD attack. And that's before you get on to the hiring hitmen and arson. Despite this, no-one really seemed to consider her mad and no diagnosis was made, possibly because no-one could think of a mental illness that would turn you into an Angie.
  • The chubby-yet-implacable-assassin Arby in Utopia suffers from a multitude of ills. His speech and mannerisms are stilted and he appears to suffer from a complete Lack of Empathy or even meaningful interaction with other people and kills at the behest of his handlers without question. It turns out he had been tortured and experimented on by his father as a child and Arby isn't even his real name, and after suffering regret from murdering a bunch of schoolchildren he proves he has Hidden Depths and performs a Heel–Face Turn.
  • Randy from My Name Is Earl, despite multiple characters claiming he isn't handicapped or disabled, just "slow" and "simple". It was eventually implied that his behavior is the result of brain damage incurred when he once inexplicably stopped breathing long enough for his parents to assume he had actually died. At one point, Earl tells Randy "The doctor did say that you were borderline artistic". (Earl isn't very bright either)
  • Doctor Who originally played off the Doctor's eccentricities as him being an alien, until later seasons established that other Time Lords viewed him as weird and unpredictable, his mountains of PTSD (which in canon he just ignores) certainly not helping. The exact nature and severity of his quirks varies wildly between actor, writer, and individual episode, but it's evident that he's largely unique in the universe and would defy diagnosis anyway.
    • The final Fourth Doctor story, "Logopolis", ups this to extreme levels when he starts being paranoid, unfeeling, scary, and rude towards his (grantled, mostly new) friends and thinking peculiarly even by his own standards. It seems like depression, but could also be a Deconstruction of the Fourth Doctor's more famous comical generic-'madness', or Time Lord old age instability.
    • The Twelfth Doctor is prone to being Innocently Insensitive and using Brutal Honesty, is less comfortable than his predecessors with lying even when it's necessary to achieve his goals, has next to No Social Skills, Hates Being Touched or touching others unless it's by someone he is really close to, a dreadful memory (he can't even recall how old his companion Clara is supposed to be!) and severe prosopagnosia, extremely expressive body language, and often lets impatience and impertinence get the better of him — all of which hides how compassionate and sensitive he actually is Beneath the Mask. Clara is effectively (and by his own admission) his "carer" in that she helps bridge the empathy gap between him and others, and in Series 9 she tutors him in better social interactions. Also, if most Doctors manage to hide/ignore their PTSD, this one (coming right off of 900 or so years spent just defending one little town in his previous life) certainly doesn't — he has a marked dislike for soldiers with only a few exceptions, doesn't want to be seen as an officer either (preferring that anyone who does anything to help him exercises their free will rather than just following orders), and questions his own actions, especially his mistakes past and present, surprisingly often.
  • Miss Fisher's Murder Mysteries: Beatrice Mason, one of the suspects in "The Blood of Juana the Mad", is generally agreed by most characters to be suffering from some kind of 'mental affliction'.
  • Artie from Warehouse 13 has poor social skills, a Hair-Trigger Temper, OCD-esque tendencies, has trust issues, and rants and snaps whenever his status quo gets challenged. This is strongly suggested to have been caused by the fact that he's spent a large part of his life working alone in the Warehouse. Having his once best friend betray him and become a Manipulative Bastard borderline supervillain probably didn't help.
  • The Good Wife: Elsbeth Tascioni, who's easily distracted by things surrounding her and led to flights of fancy by them.
  • Gotham:
    • Obviously, Young Bruce Wayne is not in the best headspace after watching his parents get killed right in front of him, but there's something else going on with him that's distinct from the trauma. He demonstrates hyper-awareness and has some obsessive-compulsive tendencies, he has difficulty relating to and socializing with children his own age, and his speech patterns are overly formal and precise, bordering on unnatural-sounding. And we viewers know that these tendencies are only going to deepen as he gets older and resolves to put them to use.
    • Nobody knows what's up with Ed Nygma (the future Riddler), but even by Gotham City standards this young man is extremely eccentric. He's perfectionistic (to the point of rearranging someone else's filing system to "improve" it), obsessed with science and riddles, and has No Social Skills, and he doesn't seem to notice when he's making other people uncomfortable.
  • Ed Chigliak on Northern Exposure has an odd clipped way of speaking, seems to avoid eye contact, and only seems comfortable addressing a few topics, like movies.
  • Sherlock in Elementary has many of the quirks that various Sherlock Holmes adaptations give to the character, along with an array of symptoms such as constant fidgeting, an obsession with order and routine, and an addictive personality (that sometimes manifests in plain addiction) that's a response to attempt to make sense of a constant overwhelming influx of sensory input.
  • Detective Murdoch's interests in Murdoch Mysteries tend toward a specific type of scientific bookishness, coupled with a mechanical aptitude, as opposed to literature or sport (though he has recognized quotations from Shakespeare and played sports well enough on occasion). At times, he is an adult version of the "little professor" explaining things to his boss Brackenreid and the various constables, among others. He often fails to understand the popularity of things like fads, fictional movies and spectator sports, and certain forms of humour leave him cold (making him an excellent straight man). Later in the series, he speaks positively of the anonymity of living in a hotel, since it allows him to avoid "useless" conversations with his neighbours. Some of his personal conversations (even those with his beloved Julia) end abruptly when he sees something that brings his mind back to his current case, and he hastily takes his leave to follow up an idea, with the others reacting to his sudden departure. All that said, his colleagues and friends seem to regard him as merely a bit unusual. Even Julia tells him, "You're not the only one who lives inside your head." It must also be said that Murdoch's continual studies (and the deep concentration to pursue them) have provided him with a highly useful expertise, though when asked about this in court, he merely replied, "I am an expert, yes."
  • Daredevil:
    • Wilson Fisk is a brilliant Chessmaster, but surprisingly shy and awkward in face-to-face interactions. He also has unusual body language and speech inflections and trouble with eye contact, he's very routine-bound, and he can be explosively angry when he's particularly embarrassed or frustrated.
    • Melvin Potter clearly has some kind of mental disability, which is acknowledged in the show, but his diagnosis is never mentioned. He's a talented designer and tinkerer and you wouldn't want to have to take him on in a fight. He also has somewhat childlike mannerisms, he's rather emotionally volatile, and by his own admission, he gets confused sometimes.
  • Barry in Best Friends Whenever lacks social skills and has trouble matching facial expressions with emotions; despite this he has a circle of understanding friends as well as being a full-on Teen Genius.
  • SCTV: Almost the entire cast is a psychologist's field day, but a short list:
    • Floyd Robertson has a Hair-Trigger Temper, is rather impulsive, struggles with alcoholism, has unstable relationships, and is prone to wild and violent mood swings.
    • Sammy Maudlin has a repetitive Character Tic (slapping his knee), frequently repeats words and phrases, appears to laugh and/or applaud when he isn't sure how to react to something, and fails to realize when he's said something rude.
    • Bobby Bittman is confirmed to be a compulsive liar, but aside from that, he's preening, egomaniacal, cocky, and grandiose with a huge helping of It's All About Me.
    • Earl Camembert, among other things, tried to eat his dinner at the news desk, went on-air stoned out of his mind, tried to have his son sit in for Floyd while the latter was out getting coffee, locked himself in a cell with violent prisoners to do an interview, and attempted to connect with the youth by roller-skating onto the set to disco music. Something is obviously wrong with him.
  • Second Chance (2016): Until Otto was nine years old, he never spoke to anyone except his sister, and only in a language he invented called Twinspeak. While he has improved significantly since then, he still avoids speaking to anyone but Mary and Arthur, and part of the reason Mary is willing to go so far to fight her cancer is because she knows he'll shut down completely without her.
  • River Tam on Firefly is introduced with vague Ophelia-style "insanity" that developed during the experiments and other tortures she endured at the Academy. Later in the series, the characters find out that much of her trauma stems from the destruction of her amygdalae and the revelation of the Miranda experiment. This still leaves some questions open, though. For example, is her madness connected to her Psychic Powers in any way? And why did the removal of her amygdalae reduce her emotional inhibition, instead of eliminating her fear response like it would in a typical brain?

    Newspaper Comics 

    Professional Wrestling 
  • Something is clearly wrong with Jon Moxley (aka Dean Ambrose, former WWE US Champion and former member of The Shield) but precisely what that something might be is unknowable. Aside from being violent and angry, which could be attributed to his traumatic childhood, Moxley also exhibits paranoia, hears "voices" occasionally, and swings wildly between despair and begging his opponents to "put him out of his misery" to being a ranting near-psychotic with a God complex.
  • Subverted in SHINE, where Leva Bates dives into several texts books and makes a case for what exactly is afflicting Kimberly based on her behavior. Unfortunately, Bates wasn't qualified to treat her and in fact may have made things worse.

    Theatre 
  • In The Pajama Party Murders, Eddie Cosmo has difficulty with metaphors, is obsessed with numbers, acts inappropriately, and is easy to enrage over small things.
  • George Banks from Mary Poppins demands precision and order, is often insensitive when he doesn't mean to be, has difficulty with emotional intimacy and romance, and recoils from physical contact (at least to begin with).

    Video Games 
  • Handsome Jack from Borderlands 2 is shown to be very emotionally unstable and impulsive to the point of buying a horse made of diamonds because he's rich, he's suffered physical abuse at the hands of his grandmother, he seems to genuinely believe he is the hero of the story, and nearly everyone he's worked with has either died or betrayed him.
  • Oracle of Tao: Ambrosia has a Sugar and Ice Personality, coupled with dramatic Tsundere moments, and occasionally has rather dramatic depressive episodes. You'd probably say she's bipolar, except her down periods are more flat, like a schizoid. She also has serious fears that she doesn't exist, and that she's hallucinating the game events. Add a few Axe Crazy episodes, and you get a very strange picture. It's clear what the cause is though, her real parents had to give her away because she was note , her adoptive parents died, and people she hired to help with her inheritance used her money and left her on the street. She has no trust in people until Nevras comes along.
  • Tales Series:
    • Tales of Symphonia has Raine Sage: a cold and calculating, but incredibly intelligent young woman who normally acts like an aloof mentor who always has to be right... and who devolves into a child-like state the moment she discovers a temple ruin, an ancient weapon or anything to do with the civilisations of past eras. She's shown to have difficulty relating to the other party members, especially in the anime where her Ice Queen elements are really played up. It's mostly treated as comedic, as her similarly-bright sibling Genis is just plain embarrassed by her enthusiasm (at one point, she even descends into maniacal laughter over the insides of an old temple). Her mother left her and Genis at a ruin that transported them to the world of Sylvarant when they were very young, terrified at the possibility that they would grow up as lab rats or labourers like most half-elves. Raine's obsession with ruins developed from a wish to be reunited with her family.
      • In a sidequest, you can learn that her mother fits the bill. It's not clear what's the matter with her but she has very clearly gone insane from the pain of being forced to abandon her children, as she spends all of her time talking to a doll that she believes is Raine.
    • In Tales of the Abyss, most of the characters show some kind of dysfunction, but only one of them has the dysfunction as the cause of their backstory, instead of the result: Jade Curtiss. He's bizarre when you first meet him - highly intelligent and mixing traits of Stepford Smiler and Stepford Snarker into one darkly humorous mask of unreadability. You later learn that as a child, he never showed any outward emotion besides a confidence in his skill and intelligence that extended into arrogance, that he liked to kill even weak and harmless monsters, and that he's 'never understood what it means to die'. This attitude led to him killing his teacher with a spell he couldn't control when he was twelve, and spending the next decade or so trying to bring her back, creating clone after clone, until he nearly died as a result and his best friend had to convince him to stop. He also shows some social awkwardness (in one skit, he joins Anise in tickling Guy as if he either doesn't understand or doesn't care that what's cute from a fourteen year old girl is weird from a thirty-five year old man) and obliviousness to his own emotions (in the Disc One Final Dungeon, Anise points out to him that he must like and respect the other party members, and Jade seems genuinely surprised to realize that she's right).
      • Guy Cecil freaks out every time a woman makes physical contact with him as a result of post-traumatic stress from having his sister and all of the maids in his household sacrifice themselves to protect him, causing him to be buried under a mountain of female corpses for days.
    • Pascal in Tales of Graces seems to have rather strange obsessions and does not understand exactly how socially awkward she can be at times. Her immature behavior makes many players surprised to discover she's 22 years old (although the visual design for her character doesn't help).
    • It seems possible in Tales of Vesperia that Raven could have some type of Split Personality. His alter ego Schwann is drastically different from his Raven persona - the first upstanding, militaristic, well-mannered and honorable, and the second friendly, goofy, flirtatious and casual. They also refer to each other as different people when they talk about each other, as in Schwann's boss fight when Schwann says Raven isn't here. However, unlike most classic examples, he's completely aware of what happens when he's in either persona, hence the ambiguity.
  • Heavy Rain has Norman Jayden. He's shown to be socially awkward and has difficulty carrying on normal conversations, though these could be argued as symptoms of his abuse of Triptocaine and the ARI.
  • Metal Gear:
    • Otacon is socially awkward and bad at reading other people's motivations, rather Literal-Minded, alternates between losing himself in his work and retreating into fantasy worlds, and has tenuous control over his emotions. It's not clear how much of this might be due to some underlying ASD and how much is stunted development from childhood trauma. His stepmother sexually abused him, his estranged father committed suicide after learning of the affair, and his stepsister was nearly drowned in the process.
    • Big Boss in Metal Gear Solid 3: Snake Eater and Metal Gear Solid: Peace Walker. Despite his charisma, he's not very sociable and tends to not handle emotions well, has a tendency for repeating other people's phrases, has unusually dedicated obsessions with guns and cardboard boxes, is surprisingly naive and trusting towards people who end up deceiving him in some major way (Miller, Paz, Huey), and has some rather unusual beliefs (such as being afraid of vampires and believing in Santa Claus well into his 30s). His sons also exhibit a few of these traits.
  • There's explicitly something wrong with the title character of American McGee's Alice, but the PTSD from her family's deaths doesn't explain the hallucinations, delusions, or episodes of mania and catatonia so severe she was institutionalized. When asked later on, American McGee confirmed that this game was a "natural extension" of the Alice series going under the assumption that the previous stories weren't either fantasies or real events, but hallucinations she honestly thought were real.
  • Touhou:
    • Marisa Kirisame actively shuns human interaction (to the point of willingly living in a youkai infested forest), has multiple obsessions that she seems to abandon as often as she acquires them, has no sense of personal property, is a severe hoarder, and is belligerent and trigger-happy even by Gensoukyou standards. It is repeatedly noted that she is much more like a youkai than a human, which would put her into Blue and Orange Morality if she weren't determined to retain her humanity.
    • Flandre Scarlet clearly has something wrong with her, though how much of that is the result of being a youkai, how much an inborn condition, and how much due to being locked in the mansion basement for nearly 500 years with little to no social interactions is a good question. Either way she has the mentality of a child and has no real concept of restraint, and has No Social Skills to the max.
    • Alice Margatroid suffers from nightmares for unknown reasons, holds conversations with her dolls, and manages to creep out everyone even in a society composed largely of monsters and supernatural beasties.
    • Yukari Yakumo is just plain weird even compared with everyone else in Gensoukyou, with only her friend Yuyuko (who gets a pass for weirdness by being dead) having any idea how to deal with her. There are hints that she was originally a human, namely Maribel Hearn, who herself is an example.
    • Koishi Komeiji has a hard to follow speech pattern, bizarre thought processes, a severe case of Attention Deficit... Ooh, Shiny!, a fascination with obscure or difficult topics while struggling to understand relatively simple concepts, and generally acts far younger than even other immature characters. In her case she sealed off her Psychic Powers, gaining control over her subconscious and having no emotions or thoughts beyond the surface, which obviously defies human classification.
    • Kosuzu Motoori, the star of Forbidden Scrollery, is lovingly obsessed with her books and nothing else, brushing off concerns of the dangers of youma books because of how interesting they are, and while she doesn't actively shun other humans she's rather awkward and avoidant around them most of the time. Her only real friend is a Wise Beyond Her Years Reincarnation, and they get along swimmingly.
  • The incarnation of Sweet Tooth in Twisted Metal: Black is noted as having insomnia and an "unidentifed mental illness" in his psych profile. Whether he is a psychopath or just an incredibly twisted individual, he's a professional serial killer, and he loves his job.
  • Dragon Age:
    • Alistair from Origins is used to people belittling his intelligence and found the silence in the monastery where he grew up absolutely unbearable; he eventually resorted to screaming just to bring people running. This discomfort with regards to his upbringing in the Chantry is referenced again in The Silent Grove, when he notes that screaming prisoners remind him of being forced to listen to the chant during his studies with the Templars, and how claustrophobic it made him feel.
    • Anders of Dragon Age II is all but outright stated to have bipolar disorder (in addition to the Demonic Possession) - his character bio mentions manic and depressive phases.
    • Merrill has trouble understanding figurative language, has No Social Skills, gets easily distracted, and borderline Hikikomori behaviour.
    • While it's likely due to being a spirit, Cole is definitely like this. In Asunder (before his nature as a spirit was discovered), he showed symptoms of several mental illnesses; some of them were explained as him being a spirit (his disassociation and amnesia), while others could only be explained as being caused by the trauma and isolation he experienced (his anxiety, depression, and lack of social skills).
  • Pokémon:
    • In Pokémon Black and White, N was raised by Pokémon without human contact to be groomed into a tool for world conquest. The result of this is an inability to empathize with humans, speaking very fast and in a lot of scientific terms, having a black and white morality viewpoint and a slight tendency to stalk people.
    • Courtney in Pokémon Omega Ruby and Alpha Sapphire. Her official character profile describes her as highly intelligent, she rarely speaks, and she is disinterested in most people and things except for a few special interests. She also has an odd way of speaking where she constantly pauses and uses few words.
  • Royce Bracket from Transistor is undoubtedly a genius, able to master the Process. But he speaks with a stilted cadence, often repeating phrases or mumbling to himself, or pausing to find words. This is reflected in his subtitles, so his awkward speaking style is completely intentional.
  • Fire Emblem games, due to having Loads and Loads of Characters, tend to have a number of characters exhibit odd mannerisms and quirks. Miriel in Fire Emblem Awakening, for instance, lacks social skills, sacrifices any sense of empathy for a tireless ambition to learn and discover things, and often is detached from reality. She also doesn't seem to feel fear, as shown in her support conversations with Lon'qu where she continually puts herself in life-threatening situations just to test if he will save her or not.
  • Monkey Island:
    • Guybrush Threepwood is shown as a Man Child who nobody respects or believes when he says he's a mighty pirate. Yet, he's very resourceful and is perfectly willing to do sociopathic things to achieve his ends. He has no problem talking to complete strangers, but is hopeless around Elaine, to the point where even after he's married her, he does whatever she says and she handles his business whilst he furthers his interests in being a pirate. Guybrush manages to alienate almost any friend he makes.
    • Wally is good at cartography and hopeless in every other situation. He's admittedly based on nerd stereotypes.
  • To some extents this trope is averted with River in To the Moon. The name of her "condition" is never outright stated, but she gets a Pervasive Developmental Disorder diagnosis by a psychologist in the game who also gives her and her boyfriend a book by Tony Attwood, a prominent real life psychologist who has written several books about Asperger's Syndrome, so that they can better understand her condition.
  • The Lutece twins in BioShock Infinite are insufferably geniuses with a very narrow range of interests, have a hard time understanding the thought processes of other people, speak in a near constant monotone with little to no visible emotion, act very rigidly and appear to enjoy constant repetition... Some of this could be chalked up to their status as Physical Gods, but the game's voxophones show they acted more or less the same when mortal.
  • Kapura from the Mata Nui Online Game is a weird, eccentric Ta-Matoran whose manner of speech sounds like deliberately awkwardly worded philosophizing, often repeats himself, and sounds as if he's unable to articulate his thoughts in a way that doesn't make them come off as random. While other Ta-Matoran do their work, he's out practicing the art of "walking quick by moving slow" (and farting) in a creepy, dead forest. He doesn't stop practicing even when conversing with the player, and casually asks if you're the Makuta or not. He's slow (except when performing his technique), deliberate and unnervingly calm among all the hot-headed, fiery Ta-Matoran. Kopeke from the same game also shows signs of this trope, being coldly antisocial, quiet and emotionless in his rare moments of talking, doing his work with robotic precision.
  • Kenny Jr AKA Duck from The Walking Dead video game, goes from talking his head off to suddenly becoming quiet after a brush in danger. He also seems to lack any social cues from not noticing a distressed Clementine after the end of episode "A New Day" to ignoring Lee's warnings that they're eating Mark's legs in "Starved For Help"
  • The eponymous Non-Ironic Clown from Dropsy. He's a trusting, grotesque clown who seems to be mute and has no desires beyond helping people, but doesn't immediately understand why they wouldn't want to be hugged by a looming, mute, bald clown with only a handful of yellowing teeth left. Despite all this, he demonstrates a certain amount of brilliance in how he solves the town's problems..

    Visual Novels 
  • Ace Attorney:
    • Vera Misham from Apollo Justice: Ace Attorney dislikes being outside or in crowds, doesn't show much emotion on her face, does not understand "rules" of social behaviour (like when she stares at Klavier in court for a very long time), and communicates either in short, broken sentences or through sketches. She also shows signs of being a savant, as demonstrated by her ability to create perfect forgeries of artwork and evidence.
    • The Big Bad of the second Ace Attorney Investigations is heavily implied to be a sociopath, despite the term never being explicitly used. The idea of trusting others is utterly incomprehensible to them, they're a master manipulator and they only see other people as tools, not caring who they hurt as long as it furthers their goals.
  • CLANNAD: Fuko Ibuki is amazingly immature for her age. Yes, she's technically younger than the rest of the cast and still has the mentality of a freshman even when she's in her twenties due to her being comatose for years, but she still acts far less mature than the average teenager, to the point where she gets mistaken for a grade schooler.
  • Katawa Shoujo:
    • Kenji is obsessed with delusional conspiracy theories to a degree that would probably have psychologists scrutinizing him for schizophrenic tendencies in Real Life, although unlike all the other disabilities in the game this is almost purely Played for Laughs. That's before mentioning his extreme dislike of being around other people or open spaces, frequently locking himself in his room for days at a time.
    • Rin definitely does not think like most people, forming connections and inferences that seemingly make no sense, switching rapidly between topics, is clearly artistically gifted even without considering she paints with her feet, and her behavior and comments can be socially inappropriate, not in the manner of someone who doesn't understand normal social interaction but more as if she simply doesn't care. Later in her route it's shown that Rin is aware to some extent of how odd she comes across to people, and the difficulties she has with expressing her thoughts, whether through words or through her art, are quite frustrating to her.
    • Misha is an inverted variant. She has no obvious disabilities, so many players are left wondering why exactly she's at Yamaku. She's a bit quirky (energetic, laughs a lot, has some volume control issues), but not to the point that she'd be considered seriously mentally unstable, and Yamaku is not supposed to cater to mental disabilities in any case. It turns out that she came to Yamaku for other reasons: namely, she wants to be a sign language instructor and Yamaku is one of the only schools that has sign language courses. It's later revealed that Misha's bubbly, hyperactive self is a facade to hide her crippling and near-suicidal depression as a result of unrequited love towards Shizune, and in the unused beta arc due to the unrequited love and previous homophobic bullying at her old school.
    • Hanako has severe social anxiety that goes beyond the normal Shrinking Violet and suffers from panic attacks.
  • Almost every mage in the Nasuverse who isn't a psychopath could qualify for this at some level. Socially distant, obsessed with their own singular interests (their magic fields, their Origins and the Akashic Records in this case), frequently have special repeated tics or actions associated with activating magecraft.
  • Steins;Gate:
    • Shiina Mayuri is a very sweet, if slow young woman. She often misunderstands or misphrases information she overhears, often has innuendo or subtlety fly over her head, and acts much younger than her age, but the most explanation we ever get is her childhood friend Okabe saying she's a little "off" and that she's always been like this.
    • Moeka Kiryu is shy to the point of preferring to communicate via text message even when face to face with the person she's talking to and responds with extreme distress if anyone attempts to take her cell phone from her, and is almost always emotionally repressed and expressionless. She's also completely dependent on her contact FB, to the point that she commits suicide once FB's messages stop in one timeline.
  • When They Cry:
    • Rena from Higurashi: When They Cry is suggested to have a mental illness even ignoring the Hinamizawa Syndrome everyone in her town has. She can be violent and have mood swings, though some of it is related to the aforementioned problem, some of her violence is understandable, and others times it's the case of another character being an Unreliable Narrator.
    • Umineko: When They Cry:
      • The Ushiromiya family patriarch Kinzo's behavior explains a lot about his children, with one flashback to WWII showing he was so depressed that he joined the army hoping to be killed in battle, and only snapped out of it when he met his lover, Beatrice Castiglioni and once she suffered Death by Childbirth went completely off the rails to the point of raping his own illegitimate daughter with said mistress because he believed she was her mother's reincarnation, an act which produced Yasu, below. Nearly every scene he's present in features him screaming at the sky.
      • Maria is nine years old but behaves far younger, has bizarre reactions (or lack of same) to events around her, and she never seems to be able to avoid hitting her mother's Berserk Button when she really should know better. There's also her Verbal Tic (which unlike most examples tends to annoy other people) and lack of focus towards anything except for her hobby of studying black magic.
      • Her mother Rosa definitely seems to have a few screws loose. Besides the aforementioned Berserk Button there's her abuse towards Maria, including rapidly alternating between screaming at her, hitting her and apologizing for her behavior, and her angry reactions to hearing about Beatrice since the young Rosa saw "Beatrice" fall off a cliff to her death and blames herself for it.
      • Erika Furudo, introduced later in the series, definitely comes off as this because of her obsessive behavior and egomania. It says something when the Ushiromiyas, who themselves are a major case of Dysfunction Junction, immediately notice something's off about her and she quickly wears out her welcome.
      • The spoilerific example of Sayo Yasuda, and by extension Shannon, Kanon, and Beatrice, whose issues seem to include pretending to be multiple people to the point of almost becoming them and probable gender dysphoria in addition to body dysmorphia caused by a horrific injury to their sexual organs that causes them to refer to themselves as "furniture" after finding out the truth about their origins mainly, the aforementioned rape of his own daughter by Kinzo.

    Webcomics 
  • Homestuck:
    • Mituna has an ambiguous brain injury from over using his psionics that leaves him with strange tics, a tendency to become incomprehensible and have dramatic and sudden mood swings. He also lacks coordination and has to wear a helmet to avoid injuring himself.
    • Jake, who was raised in almost complete isolation on a deserted island by his grandmother, has such poor social skills and is so oblivious to the feelings of others, including a tendency to ramble on about his issues without regard for the feelings of the person he's talking to. It's also implied that his Alternate Universe self Grandpa Harley (who seems to have had a normal enough upbringing, even though his stepmother was actually an alien empress) was similarly odd.
    • Clubs Deuce/Courtyard Droll is very childish (despite being a grown man who's part of a gang), gets easily excited at the smallest victory, and has difficulty paying attention to people or focusing on a given task. He also seems convinced that his fellow gangsters are just his eccentric and lovable family.
    • Caliborn/Lord English is undeniably a sociopath, but also admits finding it very hard to think clearly, often overlooks obvious solutions to his problems in favor of unnecessarily complex workarounds, has very poor social skills, lacks impulse control and self-awareness, and admits to "thinking in colours", suggesting he views the world in a fundamentally different way.
  • Lalli, of Stand Still, Stay Silent seems to think he's a cat. He sits on his haunches, sleeps in strange places and for extremely long periods of time, scratches doors rather than knocking when he wants someone to open them and has engaged his teammates in social grooming. However, in spite of all his strangeness, Lalli is a pretty well-adjusted human being (apart from having No Social Skills) and has found a way to turn his quirks into a useful career as a night scout.
  • Played for Drama with Dina of Dumbing of Age. She is obsessed with paleontology but doesn't really seem to understand other humans, by her own admission; at one point she gets depressed because some other girls mistook her for a retarded child (aside from her behavior, she looks about twelve). Her roommate Amber has tried to help her read social cues with mixed results. The creator has gone on record saying she's never been diagnosed with anything, later acknowledging that she probably has Asperger's. For what it's worth, her parents behave similarly (at least, they're very laconic).
  • In Ha from Cheese In The Trap seems for the most part just selfish, shallow and lazy, but then someone says something to set her off and she shows just how insane she is. This often involves physically attacking the people around her, though sometimes it is just shown in her sudden personality change, and her inability to be reasoned with. It's never played for laughs. Also Professor Baek hinted that Jung had some kind of disorder, but never specified what that was. He certainly has difficulty forming relationships with others, or understand how other people process the world.
  • Afkinz from Zoophobia does come across as rather odd. He has super-long hair that he lets his cat live in and sometimes hisses at random people.
  • Ethan from Ctrl+Alt+Del just doesn't seem to be capable of functioning as a normal human being. He's so obsessed with gaming that he suffers actual withdrawal symptoms if deprived of any means of gaming for more than an hour or so, his behaviour to his friends is often deeply insensitive, and his behaviour towards people he doesn't like can be downright sociopathic, to the point where he inflicts potentially murderous levels of violence against his co-worker Rob for the heinous crime of liking Counter-Strike and saying "bro" rather a lot.
  • Brun the bartender in Questionable Content. At first she just comes across as taciturn and undemonstrative, then when the bar burns down she continues to be taciturn and undemonstrative, eventually explaining when Clinton congratulates her for being calm "I'm not ... great. With emotions", and the stress is actually making it hard for her to talk at all. Later, her friend Renee says she's "not great at working out people's intentions", and she says needs a new routine now that the bar is gone.

    Web Original 
  • Killerbunnies:
    • Razelle has some sort of psychosis if her backstory is to go by. Unfortunately, in her fits of delirium, she is prone to committing violent acts if left unrestrained, although that could be part of some underlying impulse problem, worsened by said psychosis. Despite either of the two, be she coherent or not, she can be described as pleasant.
    • Coriander, according to her deviantArt description, is a rather eccentric sort with bizarre obsessions of counting to nonsensical numbers, plants, beaches, and nature in general, along with suffering a short attention span and is generally unaware of where she is, even in familiar territory, in which case, she may remember or she may forget.
    • Gas is described as being "not right in the head". However, considering what she does normally, which is playing with chemicals and making gases from them, this can be seen as a result of brain damaging side-effects.
    • Frankie, as per her profile, is described as being "ambiguous and erratic", along with the fact that she is friendly, yet tends to disregard others, and that she seems to lack some understanding of her actions.

    Western Animation 
  • Adventure Time has quite a bit of it due to being set in a Dysfunction Junction.
    • Jake has a very short attention span and often blurts things out without thinking as well as tendency to do things without thinking about consequences or the impact on others, both physical and emotional. (Though he can probably be excused by the fact that, anthropomorphic or not, he's still a dog)
    • Marceline is overly flirtatious with others, displays mild sociopathic tendencies, and seems to have trouble understanding other people's emotions.
    • Lemongrab, in particular, could keep a team of psychologists busy for weeks, with his wildly exaggerated emotions, total incomprehension of other peoples' emotions and thought-processes, extreme arrogance, contant suspicion of others, and ability to switch from pathetic to frighteningly vicious on a dime. Interestingly, his clone Lemongrab II still has issues, but is much gentler and more moral.
  • American Dad!:
    • Stan. His thought process runs on Aesop Amnesia, Insane Troll Logic, and Too Dumb to Live, and other characters often consider him insane.
    • Steve Smith. Several episodes prove that he's capable of extreme violence, self-abuse, and just plain undiagnosable problems for laughs. Roger even lampshades this with his response to Steve's plan to exact revenge on a bully by dressing up like a girl and seducing him: "Yes, let's keep that plan between you, me, and the string of therapists who won't be able to help you."
    • The Ditz Barry, though it was revealed in one episode that he is in fact a complete sociopath whose criminal inhibitions are "retarded" (their words) by powerful anti-psychotics that cause his odd behavior. Though the real Barry still shines through sometimes ("Let's kill his parents next! Let's kill them all!").
  • Archer
    • The titular character is a Psychopathic Man Child that can instinctively count bullets fired, instantly recognizes the model of every gun he sees, gets easily distracted and despite all that is an ace when killing/torturing enemies. Several characters have wondered if he is in fact autistic or if he has any other number of mental/psychological problems up to including brain damage.
    • Cheryl gets aroused by emotional and physical violence, is extremely agressive, constantly calls attention to herself, and, according to her brother, she has been a pyromaniac since she was a little girl.
  • Avatar: The Last Airbender: Azula lacks empathy note  and is a Consummate Liar to the point that Toph, the Living Lie Detector, can't tell when she's lying, and is manipulative as all get out. And yet despite her Magnificent Bastardry, when forced into social situations she proves to be cringe-inducingly inept when it comes to actually interacting with people as opposed to manipulating them. Slightly complicated by how Word of God is that this was mainly the result of her father's narcissistic influence but even as a child her mother wondered just what was wrong with her. She also demonstrates seriously inappropriate nigh-sexualized behavior towards her brother (though this seems mainly designed to creep him out).
  • Bob's Burgers:
    • All three Belcher kids to some extent. Tina speaks in a Creepy Monotone, expresses distress through long groans, openly discusses her bizarre sexual fantasies (including necrophilia), has No Social Skills and awkward body language. Gene is a Cloudcuckoolander with limited reasoning abilities and his Attention Deficit... Ooh, Shiny! so severe that his name is synonymous with getting distracted and screwing up in the Belcher family. Lousie is the most normal but she is manipulative, has a strong sense of schadenfreude, quick to anger, frequently advocates violence and often tries to escalate situations for her amusement.
    • The Pesto kids are if anything even weirder. Jimmy Junior's only apparent mechanism for dealing with his emotions is random Footloose-style dance numbers in public, and listing every weird thing Andy and Ollie do would require it's own page.
    • Mr Fischoder, the perpetually cheerful wealthy eccentric who owns most of the town is certifiably insane, most notably he seems to place no value on human life, including his own.
    • Aunt Gail is a Crazy Cat Lady, severely emotionally fragile, displays obsessive tendencies and at one point mentions being medicated. She has eaten her own lipstick, worn a dress made out of shrimp to church and shaved her cat.
  • Ed the otter from Brandy & Mr. Whiskers has something. He has awkward speech patterns, uses big words, he's also a bit on the stoic side for the most part and is also physically clumsy when it comes to sports.
  • Nonny from Bubble Guppies is a smaller example. He rarely ever smiles, has a bored, monotone voice, and is quite awkward compared with the other guppies.
  • Cleveland, Jr. from The Cleveland Show. He's a teenager with the mentality of a child, and has a number of disturbing quirks, such as an obsession with cleanliness and order, and random bursts of violence (such as strangling a mannequin head for being "so pretty"). He also believes one of his stuffed animals is alive, to the point of hiring a nanny for it.
  • From Family Guy, we have Chris and Meg. Meg has displayed some attachment problems, prone to Self-Harm, suicidal tendencies, and reckless behavior, has anger issues, and has been noted to hear voices in her head. Chris, on the other hand, has displayed violent tendencies (i.e drowning a mouse in a puddle) and, like Meg, anger issues, at the same time, he displays some lack of comprehension and basic understanding.
  • With Cheese from Foster's Home for Imaginary Friends, you can't really pin down what's wrong with him. He clearly was imagined by a special needs child (this is made painfully obvious when he's introduced), but what exactly that special need was is left ambiguous. Most likely it's just an amalgam of general "mentally challenged" stereotypes.
  • Hey Arnold! has the title character's cousin Arnie, who the other characters think is "dull" and "slow". His hobbies include counting things, reading ingredient labels (along with seemingly knowing what they are and how to pronounce them) and collections (specifically balls of lint and "plain flavored" gum), displays muted outward signs of emotion, and seems to have difficulty in social interaction (he constantly snorts and winks one eye at a time instead of blinking together).
  • King of the Hill: Dale is an awkward, paranoid Cloudcuckoolander whose conspiracy theories border on outright delusional — and yet despite his constant suspicion of everyone and everything, he's completely oblivious to actual conspiracies that are obvious to absolutely everyone else, such as his wife's affair with John Redcorn.
  • In The Legend of Korra, Eska and her twin brother Desna are almost emotionless and speak in a creepy monotone. Eska has occasional emotional outbursts, and an abusive treatment of poor Bolin and violent reaction to him running out on the wedding. She isn't exactly rational, either, as she blames Korra for the ruined wedding, even though it's rather clear in the show that she and Bolin are Just Friends and Korra is way more interested in Bolin's brother Mako. Like Azula, the twins didn't have the best upbringing; their daddy is the season's Big Bad. Unlike Azula, they were not shown to have been just the same when little, so maybe when you've lived their lives the world really is just that dull.
  • Daffy Duck in The Looney Tunes Show (carried over somewhat from older cartoons in which he was clearly insane, but not debilitatingly so). Bugs Bunny guesses that he's "a sociopath, "a narcissist" and "probably a psychopath". (He also sometimes seems to be unable to tell fantasy apart from reality — just see the music video for "The Wizard.")
  • Draggle from the original My Little Pony series shows signs of many disorders, and by default of her family life, Stockholm Syndrome. Also, her voice in "The End of Flutter Valley" indicates, erm, slowness due to Flanderization messing with her intelligence.
  • My Little Pony: Friendship Is Magic:
    • Pinkie Pie is a really eccentric Cloudcuckoolander who seems to inhabit normal reality only part-time and is almost pathologically cheerful and silly, with an obsession with parties... except that when a misunderstanding makes her believe her friends are excluding her, she immediately snaps into a state of paranoia and depression so severe that she becomes delusional and starts hallucinating. Pinkie has shown that she is aware of how annoying that she can be, but is either unwilling or incapable of altering her behavior. She is also implied to create the machines that she uses, and has displayed incredible memory and eye for detail.
    • It seems to run in the family because Pinkie's sister, Maud Pie also displays eccentric behavior of her own. She shares her sister's literal-mindedness, but unlike Pinkie, she displays practically no emotion whatsoever. She also talks in monotone and has a narrow-minded obsession with rocks. This general behavior makes her so un-relatable to Pinkie's friends that they don't really know what to make of her and don't seem to "click" socially speaking. Maud is cognizant of this though.
    • The official portrayal of Derpy Hooves showed her as ignorant to the scale of dangers and also simple in how she treats things, giving the impression that she's a bit... off.
    • Twilight Sparkle has Super OCD to the point that a disruption to her routine can induce a panic attack, and while fiercely good at management and organisation she approaches everything in her life as a rigid task; Celestia had to largely trick her into making friends through her "friendship reports". She's seen using breathing exercises to keep herself in check by the later episodes of season three, and has learned to interact with other ponies less clinically, but it's clear that even in-universe this is a real problem for her that she's working on getting better at dealing with.
    • Fluttershy is almost never seen with other ponies besides the other members of the Mane Six, preferring the company of her many animal friends. She has severe anxiety if she has to socialize beyond basic business transactions and small talk, with full-blown panic attacks (complete with hyperventilation and hallucinations) if ponies laugh at her.
    • Starlight Glimmer, the Arc Villain of the fifth season premier, displays symptoms for several disorders. She's absolutely obsessed with keeping the town under her control as harmonic, orderly, and equal as possible, to the point of making sure everypony's mane is identical, even if she has to rearrange it herself. She also shows extreme paranoia and distrust of those different from herself, to the point of not even trying to get to know the rest of her town until she'd convinced them to give up their Cutie Mark or outright stolen it (as Sugar Belle's plead with her attests to). And when something enrages her, she goes from calm and composed to explosions of anger and psychotic rage to the point of nearly attacking, and then actually attacking others who were supposedly friends. Unlike the mane six, these traits aren't Played for Laughs and combined with the power she has at her disposal, she's an extremely dangerous threat, especially since she isn't captured or reformed by the end of the two-parter. This gets to the point where she has three cameos stalking the Mane Six for the express purpose of revenge against them.
  • Phineas and Ferb:
    • Baljeet is dependent on routines and clear direction, unsocial, observant but somewhat oblivious and emotionally stunted, able to focus for long periods on repetitive behaviors.
    • Phineas is unaware of Isabella's advancement towards him, Ferb rarely speaks (not at all in some episodes), and both are incredibly savvy in machines. It's shown that Phineas apparently has a pathological need to invent, as in one episode he suffered Heroic B.S.O.D. when he couldn't invent anything for hours, and the same may apply to Ferb; he did say he felt like he was going to scream if he didn't invent anything, though nothing came out of it.
    • Candace is extremely obsessive over busting her brothers, and will do crazy things to do so. "Monster from the ID" also proves that her head is quite messed up.
  • Ralph Wiggum from The Simpsons. He acts much younger than his age, has weird mood swings, is quite the Cloudcuckoolander, doesn't seem able to tell fantasy apart from reality, and one episode shows he hallucinates. It's stated numerous times that he's on meds and Chief Wiggum, his father, mentions that Ralph goes to a "special school" as well as Springfield Elementary. A later episode depicted a flashback with Chief Wiggum holding a baby Ralph, who is drinking out of his bottle. Wiggum accidentally drops Ralph, and after he picks him back up, Ralph is no longer able to find his mouth with the bottle.
  • The titular character of SpongeBob SquarePants is a Man Child that is obsessed with working on the Krusty Krab (an episode has him going crazy when he's forced to take a vacation) and, despite having the knowledge necessary to drive, can't do it because he gets too nervous when he's behind the wheel.
  • Steven Universe:
    • Pearl gets obsessed with certain subjects like swords or gem history, seems to stim by clenching her fists and other gestures when she gets excited, takes hyperbole, sarcasm, and humour literally, has an inability to pick up on social cues, has difficulties empathizing with those she doesn't have a close connection with (ie: most humans), is ultra-logical most of the time but highly anxious and emotional in stressful situations, and has trouble understanding other people's perspectives. Given that the other Gems can seem to glean a basic understanding of earth and its inhabitants, Pearl's behavior may not be explainable by reference to her outsider status alone. This is on top of the rampant PTSD symptoms she displays in relation to the Great Offscreen War.
    • Ronaldo's I Just Want to Be Special and I Reject Your Reality tendencies, combined with what a Conspiracy Theorist he is, could be suggestive of some form of psychosis or personality disorder. He is at the very least slightly off.
    • Onion is almost completely non-verbal and prone to odd behaviors. This is especially seen when he tries to bond with Steven in "Onion Friend" and does things like feed a mouse to a snake or show Steven a video of the day Onion was born.
  • Superjail!: Where to begin with the Warden? He is shown to be very intelligent and yet has the mentality of a child. He also interacts better with animals and machines than with people and has sociopathic tendencies, especially when he's murdering his own inmates. (Although these are usually Played for Laughs.) Oh, and when he does befriend/fall in love with someone, he tends to be clingy and almost a bit of a creep around them.
  • Ice Bear from We Bare Bears rarely speaks, refers to himself in the third person, has an axe for a Security Blanket, and is never referred to by his name by any of the other characters. He's also a very skilled cook, knows a few different languages, and likes to tinker with electronics.

http://tvtropes.org/pmwiki/pmwiki.php/Main/AmbiguousDisorder