History Heartwarming / WhoFramedRogerRabbit

** After getting rescued by Eddie and untied by him, Jessica rushes to Roger, kisses him over and over again and calls him a pillar of strength. It's so cute.

** It's also touching that Jessica was willing to put herself through something so unpleasant and potentially humiliating for the sake of her husband's career, because she knows how much Roger loves his job.

* The first (and sadly ''only'') team-up between WesternAnimation/MickeyMouse and WesternAnimation/BugsBunny was a wonderful little thing. Unlike WesternAnimation/DonaldDuck and WesternAnimation/DaffyDuck, who spent ''their'' scene competing, Mickey and Bugs' scene shows them being friendly and working together to mess with Eddie.
** Although in a DeletedScene, it's revealed that Donald and Daffy's aggression to each other is AllPartOfTheShow and no genuine ill will is held between the two cartoon ducks off the stage. In the deleted scene, Eddie sneaks backstage and hides in a replacement piano, the two are then seen quite amicably conversing with each other, before they decide on a whim to sit at the piano and practice together. And when the piano isn't playing as expected, because Eddie's inside it, they work together on figuring out why it's out of tune.

* When Eddie meets WesternAnimation/BettyBoop in the Ink and Paint Club as a cigarette girl, he's shocked to see her there, and Betty explains that work's been a bit slow for her since technicolor cartoons have become the norm. But being who she is, Betty keeps an upbeat attitude giving him her trademark 'boop-boop-be-do-boop'. Eddie, the guy who at that point despised any and all toons that he met, actually gives her a genuine smile and remarked, "Yeah, you still got it." Says a lot for the guy that up until that moment has reacted to all toons with annoyance and hostility.

** This bit is poignant for several reasons actually. First off, when the movie starts, the two seem to be arguing because Dolores has loaned Eddie money that could cost her the job at the bar, so this scene implies that Eddie has finally realized how much he has put Dolores through and [[IWantMyBelovedToBeHappy cares enough to ask her to seek her own happiness because he's done dragging her through the mud]]. Secondly, however, Dolores' comment shows that she [[YouAreBetterThanYouThinkYouAre still sees the good in him and still cares about him, despite all he's put her through]].

** Even before Dolores shows up, after Roger asks Eddie straight-up about what happened to him that led to his hatred towards toons, Eddie decides to come clean and reveals what happened to his brother, Teddy. This is heartwarming for two reasons:

*** 2.) Roger's got nothing but sympathy for what Eddie's had to go through since his brother died--Roger's also horrified that it was a toon that killed Teddy, especially since (as previously mentioned at earlier points in the movie) toons are meant to be funny, make people laugh and feel happy.

* When Eddie, well-established as an alcoholic, decides to take a drink before entering Toontown, but then visibly toughens his discipline and instead uses the bottle of whiskey as target practice.

*** Speaking of the gun, when Eddie opens the lid for the bullets, they are mentioning how they haven't seen him in five years. Are they angry that he's ignored them all this time? Nope! On the contrary, they are ''overjoyed'' to see him again and when he opens his gun, they readily jump in with an excited yell.

** Related to the above: one of the newspaper clippings showed how Eddie and Teddy solved a kidnapping of WesternAnimation/DonaldDuck's nephews (Huey, Louie and Dewey), and to celebrate their return, they threw a party which all of Toontown attended.
* Marvin Acme may be a bit of a ManChild, but like his buddy Roger, all he wants to do is make people laugh. He sprays in disappearing/reappearing ink on Eddie, but is quick to apologize when he sees Eddie doesn't find it funny. Even his will refers to the toons as "those lovable characters!"

* Though his relationship with Jessica was both inappropriate and a sham, it really says something that Marvin Acme trusted her enough to leave his will with her, knowing she'd get it into the toons' hands.

!!Meta

* [[https://s-media-cache-ak0.pinimg.com/originals/02/cb/5d/02cb5d6b04efa41e17f28c459c1f103a.jpg Roger and Jessica at Disney.]]
* When casting WesternAnimation/BettyBoop, they got [[https://en.wikipedia.org/wiki/Mae_Questel Mae Questel]], who had voiced Betty the longest with 150 shorts to her name, to reprise the role, ''fifty years'' since her last appearance as the character. Also gives her line about "I've StillGotIt, Eddie" a bit more RealitySubtext.
* Due to Mel Blanc's failing health, he was unable to provide the loud, growly vocals for WesternAnimation/YosemiteSam, so Blanc instead passed off the character to Creator/JoeAlaskey, thus beginning a passing of a torch for multiple other voice actors to carry (Alaskey, Creator/JeffBergman, Creator/BobBergen, Creator/GregBurson, Creator/BillyWest, and others).