The keyboard battle between Jeremy and Teh_Masterer in Season 1. "Console style!" "Arcade style!"
One scene where Doug JUMPS OUT OF A TREE while Jeremy is giving a routine monologue had this troper falling out of his chair.
Dave trying to back out of going with Jeremy to talk to Anastasia about Jeremy deleting her World of Warcraft character. "Dude! You deleted her shit!"
The celebratory dancing Jeremy does when he is off the hook for deleting Anastasia's Level 70, full tier 5 World of Warcraft character. Anastasia actually took the time to do more real life things when it happened and never found out Jeremy was responsible.
"Your pony died cuz it wasn't pretty enough? AGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH"*