| 1 | [[WMG: This series is set in an AlternateUniverse in which Holmes doesn't have a mood disorder.]] |
| 2 | Which changes a lot. He never developed a cocaine habit because he didn't have the incentive to self-medicate. His somewhat more amiable overall temperament in this adaptation is a combination of less hostile brain chemistry and the absence of the psychological side-effects of drug use. |
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