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1See also AndCallHimGeorge.
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3[[AC:FanWorks]]
4* ''Fanfic/SorrowfulAndImmaculateHearts'': In "Gone Fishing", Clark mentions that his parents once experimented with keeping rabbits for food, and Bruce appeals to him to "tell me about the rabbits", which Clark recognizes is a reference to ''Of Mice & Men''.
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6[[AC:Film - Animation]]
7* ''WesternAnimation/SharkTale'': Lenny's name is probably inspired by Lennie Small. There's even a short AndCallHimGeorge moment with Oscar.
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9[[AC: {{Film}} -- Live Action]]
10* ''Film/Gremlins2TheNewBatch'' has two Gremlins named after George and Lenny. Naturally, George is a grumpy Gremlin who rarely smiles, and Lenny is a dim witted and silly Gremlin.
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12[[AC:{{Literature}}]]
13* Sal from ''Literature/OnTheRoad'' quotes, "You won't tell what he done up in Weed, will you? What'd he do up in Weed? You won't tell will you? What'd he do up in Weed?" to make Terry laugh.
14* In ''Literature/TheStateOfGrace'', the "quiet room" at Grace's school is essentially a glorified store cupboard, complete with leftover copies of ''Of Mice and Men''.
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16[[AC:WebAnimation]]
17* ''WebAnimation/TheFlashTub'': In a scene from Tub Bites 2 (which parodies WebAnimation/HomestarRunner), Strong Mad "pets Marmalade too hard, now she don't move no more", leading Strong Bad to pull out a gun and "tell him about the rabbits".
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19[[AC:WebVideo]]
20* Grant Wisler's video [[https://www.youtube.com/watch?v=jzcD3OffhU8 How Internet Humor Progressively Gets Worse]] includes a direct parody of the ending.
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22[[AC:WesternAnimation]]
23* ''WesternAnimation/AmericanDad'': The title of "Of Ice and Men" is a reference to this book.
24* ''WesternAnimation/{{Animaniacs}}'': The Rita and Runt cartoon "Of Nice and Men" is a loose WholePlotReference to ''Of Mice & Men'', with a cameo appearance by Lennie and George as portrayed by Creator/LonChaneyJr and Creator/BurgessMeredith in the 1939 film version.
25* ''WesternAnimation/Animaniacs2020'': The title of "Of Mice and Memes".
26* ''WesternAnimation/BungleBrothers'': Joey's temperament is clearly patterned after Lennie; as such, George is his George.
27* An episode of ''WesternAnimation/ChipNDaleRescueRangers'' is called "When Mice Were Men".
28* ''WesternAnimation/KingOfTheHill'':
29** "Of Mice and Little Green Men".
30** Peggy scoffs at John Steinbeck during a performance of ''Of Mice and Men''.
31* ''WesternAnimation/LooneyTunes'' codified the AndCallHimGeorge trope. Willoughby the dog from ''The Heckling Hare'' (1941) and Hugo the snowman from ''The Abominable Snow Rabbit'' (1961) are based directly on Lennie.
32* Leni Loud from ''WesternAnimation/TheLoudHouse'' is named after this book's Lennie. This is fitting, as they are both unintelligent, although Leni is simply TheDitz rather than intellectually disabled. In fact, [[WhatCouldHaveBeen in development]], Leni was going to be a SuperStrongChild who [[DoesNotKnowHisOwnStrength did not know her own strength]], before being changed into a fashionista.
33* ''WesternAnimation/RobotChicken'' once had a sketch where characters from ''WesternAnimation/RockyAndBullwinkle'' reenacted key scenes from the story.
34* ''WesternAnimation/TexAveryMGMCartoons'' also revel in ''OM&M'' parodies.
35** "Lonesome Lenny" is probably the ultimate example of this. "You know, I had a little friend once — ''[[PleaseWakeUp but he don't move no more!]]''". At which point Screwy Squirrel (the "little friend" in question) pulls a sign saying "Sad ending - Ain't it?" [[KilledOffForReal Noticeably, this is the last Screwy Squirrel Cartoon chronologically]].

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