Line #120 DelicateAndSickly/VideoGames


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8	!!Female Examples
9	* In ''VideoGame/AdvanceWars: Days of Ruin'', Isabella/Catleia fills this role early on due to being infected with the mysterious floral virus. Will/Ed is the one to cares for her most, but because the virus only affects younger people, he'd be in danger if he was around her too much. Due to her strange memories, the crew manages to find a cure for it. Unfortunately, the virus later evolves to be able to affect matures as well.
10	* Yasumi Aizawa in ''VisualNovel/AoiShiro'' is one of these. [[spoiler: Until it turns out she just needed a little blood]].
11	* ''VideoGame/AITheSomniumFiles'': [[spoiler: The [[GenkiGirl sweet and bubbly]] Iris is suffering from a terminal brain cancer, and several moments in the game foreshadow the fact by showing her suffering symptoms like nausea and chills. She tries to maintain her optimism despite it all, not even telling people about her disease out of fear. She succumbs to the cancer of at the end of her route, but thankfully is cured in the GoldenEnding.]]
12	* Fana from ''VideoGame/AvalonCode''. Interesting in that you can actually heal her by removing the illness code attached to her, but this requires a series of related plot events, as you can't just pluck out the code and slap it on something else (codes with this property are marked with spiked borders).
13	* Subverted in ''VideoGame/BahamutLagoon''. Frederica is a [[SquishyWizard frail mage]] suffering from a mysterious sickness that makes her prone to fainting. If you [[VideoGameCrueltyPotential swipe it from her]], you learn her so-called medicine is enough [[HealingPotion healing potions]] to drown a horse. She's actually a [[GRatedDrug recovery item junkie]] going through withdrawals. She also doubly [[TemptingFate tempts fate]] by saying she will open an [[PhlebotinumOverdose item shop]] once the [[{{Retirony}} war is over]].
14	* Beatrix from ''VideoGame/{{Battleborn}}'' was born with a terminal disease that gave her a very weak body, a thing that is looked down upon by Jennerit society which greatly values strength. Because of this, she originally didn't have long to live. However thanks to her mother's lobbying to have Beatrix sustained for her genius, Beatrix became something akin to ''ComicBook/{{Deadpool}}'', an immortal stuck with an otherwise sickly body. Excerpts from her diary from the lore in [[https://forums.gearboxsoftware.com/t/battleplan-32-12-22-16/1552633 Battleplan 32]] reveal her thoughts about her illness.
15	-->There once was a girl named Trix\
16	Whose body nobody could fix—\
17	She went to the doctor\
18	Who stabbed her and stocked her\
19	With every pill in the mix.
20	--->A poem by Beatrix from her diary
21	* Eve in ''VideoGame/BlasterMasterZero2'' plays this role due to the mutant infection [[HappyEndingOverride not quite having gone away]] and the plot involves racing to her home planet to find a cure. Unlike most examples, her disease shows a clear sign of BodyHorror.
22	* In ''VideoGame/BoxxyQuestTheGatheringStorm'', Catie passes out whenever STORM wipes a site, due to her link with the goddesses and [[spoiler: being a piece of Virtua]]. As STORM erases more of the Internet, Catie’s health begins failing, and she even slips briefly into a coma at the start of Chapter 8. Even after she wakes up, her sprite is noticeably paler from that point on until you finish the game.
23	* Victoria F. Stein from ''VideoGame/BravelyDefault'' is a dark twist on this trope; while she was subjected to an incurable disease, she was treated by Victor and his father Vincent. The treatment was imperfect, however, and while Victoria can move freely, not only did it stunt her growth, but she is subjected to [[spoiler:increasingly frequent]] seizures, and the continued trauma has made her [[AxCrazy a different kind of sick]].
24	* ''VideoGame/BreathOfFireIII'' subverts this during the [[InevitableTournament Contest of Champions]]. Emitai, one of the competitors, visits the heroes before their bout (which is weighed against a spellcaster like him because the arena has AntiMagic) and introduces them to his daughter; he claims to be in the contest to earn her an operation that will cure her disease, and asks them to throw the fight. As one of the heroes is being held hostage, they refuse. After the match, however, if you visit Emitai's dressing room, you learn that it was a giant fraud on his part to get his opponents to forfeit. Just to make this clear, after the TimeSkip, you can find Emitai again (and recruit him as a master); his daughter has grown up and is rather embarrassed with him.
25	* Tomoki in ''VisualNovel/Canvas2''. However, the surgery she needs is actually quite easy and not that expensive. Not even that risky. She's actually afraid it will work and she'll be lonely.
26	* Erika in ''VideoGame/DigimonStoryCyberSleuthHackersMemory'', the team's MissionControl, is a young ShrinkingViolet with a [[YourDaysAreNumbered terminal brain disease]] that requires her to undergo BrainUploading semi-regularly in order to relieve the strain it causes.
27	* ''VideoGame/EldenRing'' plays with this trope in regard to Malenia, a demigod infected with [[MysticalPlague Scarlet Rot]] from birth. When you meet her in-game, [[DisabledDeity three of her limbs have been replaced with prosthetics]], her remaining arm does not look long for this world, her [[EyeScream eyes are gone]], and her body is scarred all over by the Rot. [[SlidingScaleOfGameplayAndStoryIntegration In gameplay, this results in her having relatively low resistances to most status ailments because of how the Rot has weakened her body]]. Her introductory cutscene emphasizes her vulnerability, as she comes out of a long coma and slowly puts on her prosthetic arm while recounting the nightmares she's had while unconscious. The fact that she's ''still'' [[{{Superboss}} the hardest boss in the game]] says ''a lot'' about [[{{Determinator}} Malenia]].
28	* ''Franchise/FireEmblem'' has three cases:
29	** In ''VideoGame/FireEmblemTheBlazingBlade'', [[GentleGiant Dorcas]]'s wife and VictoriousChildhoodFriend in an ill girl named Natalie, who has had problems in her leg ever since she was a little girl. One of the earlier missions is to keep her safe her inside of some abandoned ruins, and if Lyn talks to her husband who is in the enemy group, you can make him defect and [[HeelFaceTurn join your group]].
30	** In ''VideoGame/FireEmblemTheSacredStones'', [[spoiler: Orson's wife Monica]] was an ill girl who died prior to the story. [[spoiler: Her husband loved her so much that [[DespairEventHorizon he fell into utter and complete despair]], [[LoveMakesYouEvil and defected to Grado when given the chance to have her revived]].]]
31	** In ''VideoGame/FireEmblemAwakening'':
32	*** ShrinkingViolet Noire says she's anemic, and some of her lines have her saying she gets tired much easier than the other characters.
33	*** Subverted with [[CuteClumsyGirl Sumia]]. In a support with Henry, he notices [[spoiler: after their FreakyFridayFlip]] that her heartbeat is faster than normal and believes she has a heart murmur. It turns out that since this is [[RelationshipUpgrade their S level support]], the super fast heartbeat happens because [[LoveTropes Sumia has fallen in love with Henry and is nervous around him]]; when she gives him her LoveConfession, he realizes [[LoveEpiphany that the same thing happens to him]] and then he asks her to marry him.
34	* ''VideoGame/GranblueFantasy'': Ferry's [[TheCutie little sister Firra]]. During their childhood (long before the start of the plot), Firra suffered from a chronic disease that left her bedridden for days on end, which is why she eventually (but reluctantly) left her family behind on their [[WorldInTheSky small island]] to seek treatment elsewhere. She never returned. Much of Ferry's story is about finding out what happened to her little sister.
35	* Occurs a couple of times in the ''VideoGame/{{Growlanser}}'' series:
36	** ''Growlanser II: The Sense of Justice'' includes Charlone's younger brother in this role.
37	** ''Growlanser 3'' has this as part of [[spoiler: TheDragon's motivation to side with the BigBad]].
38	* Taimi of ''VideoGame/GuildWars2'' is an Asuran child who suffers from a disease similar to multiple sclerosis, rendering it painful to walk for significant distances. She gets around this by riding in a [[HandicappedBadass combat-ready golem chassis]].
39	* ''VideoGame/DotHackGU'' has Aina, Oban's sister who plays [[ShowWithinAShow The World]] because it's the only way for her to communicate with her brother (He's in Japan, she's receiving treatment in Germany). She would've received a crucial treatment long ago... but unfortunately she became a Lost One (a victim of the [[PlayerKilling PKer]] Tri-Edge. [[spoiler: This greatly eats away at Oban's consciousness because ''he'' is Tri-Edge due to the AIDA infection. His plans throughout the series are so that he can free her mind from the game.]]
40	* ''VideoGame/HarvestMoonMagicalMelody'' features Dia, a girl you can romance who is incredibly ill from some vague disease. As such she spends every waking hour in the hospital and you have to come visit her. You could always just woo her nurse instead.
41	* ''VideoGame/HonkaiImpact3rd'': Sora couldn't possibly have more "cute-ill" traits: she is a child with pale skin and white hair, has tattered clothes, bandaged head and arms – one of which is in a sling – and is constantly on an IV that is held by a small robot floating next to her.
42	* Kaoru Watabe from ''VideoGame/TheKingOfFighters'', who is in a wheelchair at the start of KOF'97. She has only started to take her first steps out of it by the time she meets her idols, the Psycho Soldiers. [[spoiler: Around KOF 99 her health has improved dramatically, atleast enough to have her [[BigDamnHeroes help the group out of the NESTS base]].]]
43	* Claudia, the main character in ''VideoGame/LegendOfFae'' has a leg brace due to contracting polio as a child. Fortunately, she can still kick butt using her affinities with the elemental spirits.
44	* In the JRPG ''VideoGame/LostOdyssey'' the player can acquire an ingame codex entry of the maincharacters past experiences. One in particular centers around an Ill Girl whom liked to hear his stories of far off places when ever he stopped by. The codex ends with the last encounter with this Ill Girl has her comatosed and on the brink of dying when he arrives to tell her one last final story.
45	* ''VideoGame/LoveNikkiDressUpQueen'' has two of these:
46	** The BigGood of the game, Queen Nanari of the Lilith Kingdom, has such a weak health that she hasn't been seen in public for years and her NumberTwo, Sir Nidhogg, has to handle almost everything. Even her members of her own family (like [[spoiler: her younger brother, Prince Royce]]) can only visit with her on a limited basis. The Nanari that spirits the titular Nikki and her cat Momo to the world of Miraland is actually a product of AstralProjection, and disappears few later.
47	** While not as frail as Queen Nanari, Nikki's IdenticalStranger Bai Jinjin appears to have a weak constitution. When she and her boyfriend Zhong Lizi headed towards the frigid North Kingdom [[spoiler: after the attempted kidnapping at the Designer's Tea Party]], her health deteriorated to the point that they were forced to return to their homeland, the Cloud Empire.
48	-->'''Zhong Lizi:''' "The further north we went, the worse Bai Jinjin's condition would get. Maybe she just can't bear the freezing weather."
49	* ''VideoGame/LufiaIIRiseOfTheSinistrals'' has Leefa, an orphan who sells flowers for a living. (In [[VideoGame/LufiaCurseOfTheSinistrals the remake]], she has siblings.) The party ends up climbing a dangerous mountain to get her a special rare flower -- [[ContinuityNod a flower that ends up being named "priphea"]].
50	* Jessica from ''VideoGame/ManaKhemiaAlchemistsOfAlRevis''. One alchemist, [[spoiler:who turns out to be TheHero's "father", sort of]], cured her ... at the cost of her life energy. In short, she got better, but her life was cut in half ''at least''.
51	* In ''VideoGame/MitsumeteKnight'', the SpiritualSuccessor of ''Tokimeki Memorial'', the resident Ill Girl is [[{{Meganekko}} Sarah]] [[HotForStudent Pixis]] ; she suffers from a heart disease that prevents her to go outside, and the Asian (the player avatar) gets to meet her as his private teacher. Other Ill Girls are [[TheWoobie Sophia's]] [[TheUnfavourite estranged mother]] and little brother, Dolphan's Queen, as well as [[spoiler:[[HospitalHottie Teddie Adelaide]], Sarah's nurse and friend, who suffers from the same heart disease as her and thus why the two are close]].
52	* Yonah from ''VideoGame/{{NieR}}'', who is infected with the Black Scrawl Virus, prompting her [[PapaWolf father]]/[[KnightTemplarBigBrother brother]] (depending on which version you buy) to go out and fight his way to finding a cure. Later on, it is revealed that [[spoiler:Kaine]] is also infected.
53	* Mary/Maki Sonomura in ''VideoGame/Persona1'' is introduced as an Ill Girl, but when demons arrive to the scene, she suddenly got back up. [[spoiler:Turns out this healthy Mary is the 'Ideal Mary', imagined by the real, ill Mary, who dreamed of her own world where one of the aspects there is that she's healthy, and by some complicated means, it's coming to take over reality.]]
54	** [[MissionControl Fuuka]] of ''VideoGame/Persona3'' is this to a lesser extent. It rarely comes up over the course of the game, but she's a total non-combatant with no interest in any kind of physical activity, the smallest and slightest member of the party who isn't ten years old, and Yukari mentions that she is often out of school due to illness.
55	* In ''VideoGame/PotionPermit'', your first patient is Mayor Myer's daughter Rue, who had been stricken with a long-term illness. Your dedication in curing her is what inspires Myer to ask for your help around Moonbury Town.
56	* Em in ''VideoGame/{{Prelude}}'' is another adult example. She has an unspecified ailment which makes her tire easily and start coughing when she's been outside for too long and which prompted her father to discourage her from singing due to the vocal strain.
57	* ''VideoGame/ProfessorLaytonAndTheLastSpecter'' has [[spoiler: Arianna; she is cured a year after the events of the story.]]
58	* ''VideoGame/ProjectRemedium'' opens with a young, unnamed girl getting infected by an unknown new viral strain, one too powerful for modern medicine to counter. To save her life, a thousand experimental [[NanoMachines nanobots]] are injected into her bloodstream, and you play as one of the many bots fighting different viruses.
59	* Muse from ''VideoGame/RomancingSaGa3''. Surprisingly enough, she is one of the better characters to recruit after [[spoiler:she is cured of her sickness]].
60	* ''VideoGame/SakuraWarsSoLongMyLove'' has Diana Caprice, the niece of the New York Combat Revue's commander. When she is introduced, she is wheelchair-bound and all but convinced that she will die in the very near future. The chapter that sees her inducted into the Revue as a STAR pilot revolves around helping her find the will to live. She eventually ditches the wheelchair when she resolves to survive. [[spoiler:At the end of the game, she reveals that she will undergo surgery in the hopes of extending her life.]]
61	* ''VideoGame/SilentHill2'' has Mary, a rare adult example. Naturally, she has the IncurableCoughOfDeath, too. The real rarity is the fact that she dies before the start of the game and is only seen and heard in flashbacks [[spoiler:or maybe not.]] Even rarer still is that the "delicate and beautiful" part is painfully averted; Mary's specific illness is not made clear, but the physical degeneration caused by it destroyed her looks and made her look aged and haggard, along with prompting nasty mood swings where she would lash out at her husband James, which also took a huge emotional toll on him.
62	* Maria Robotnik of the ''Franchise/SonicTheHedgehog'' series had NIDS. In fact, Gerald Robotnik's creation of Shadow the Hedgehog was his attempt to save Maria's life.
63	* Ameena from ''VideoGame/StarOceanTillTheEndOfTime'', who's also an Expy of [[VideoGame/FinalFantasyVII another flower-selling girl]]. It ends [[DiabolusExMachina even worse than this implies]].
64	* Subverted in ''VideoGame/SuperRobotWarsOriginalGeneration'': Ryusei's mother is an adult Ill Girl, but it's due to a military project she used to work on as a psychic destroying her body. Her son has ended up being "recruited" by the same project in exchange for paying for her hospital bills.
65	* ''VideoGame/TalesSeries'':
66	** Colette from ''VideoGame/TalesOfSymphonia'', who ends up suffering from a couple various ailments, the first being Angel Toxicosis [[spoiler:Actually is pain from her soul being consumed by the Cruxis Crystal, as part of the World Regeneration Journey]], and the second Chronic Angeleus Crystallius Inofficium actually ''does'' disfigure her (In the one cutscene where it's visible) and you spend a while (half of disc 2) getting the cure for her.
67	** Hilda from ''VideoGame/TalesOfRebirth'' was one as a child. [[HalfHumanHybrid Huma/Gajuma hybrids]] in general tend to have frail bodies, and many don't survive infancy because of this.
68	** Laphicet Crowe in ''VideoGame/TalesOfBerseria'' suffers from chronic fevers, and the game opens with him getting over his latest bout while Velvet goes hunting so she can sell the meat and buy higher-quality medicine. Later, the party meets another child who has the same condition and learn that it's the rare "Twelve-Year Disease." Sufferers get a fever every twelve days, gradually increasing in severity until they turn twelve, upon which they suffer one last fatal fever. [[spoiler:Laphicet Crowe found this information in all the reading he did while sick. Knowing that he didn't have long to live, he secretly asked Arthur to use him as the second sacrifice to revive Innominat. Laphicet the malak's character sidequest has him befriend the second child and decipher ancient texts for a cure.]]
69	** Cheria starts ''VideoGame/TalesOfGraces'' like this, but she gets better when Asbel returns.
70	* In the ''VisualNovel/TokimekiMemorial'' series, there's [[{{Meganekko}} Mio]] [[CuteBookworm Kisaragi]] of Tokimemo 1, who suffers from anemia and thus and can't handle violent physical activities and emotions, and Hotaru Izumi of Tokimemo 3, who had to stay for a long time at the hospital, and still suffers from some aftereffects, due to a car accident a few years prior the game's proper, which also [[spoiler: [[TheMourningAfter cost the life of her dear boyfriend]]]].
71	* Patchouli Knowledge from ''Franchise/TouhouProject'' is really sick. She suffers from asthma, anemia, and Vitamin A deficiency because of her refusal to leave the library she lives in for ''centuries''[[note]]and also because of all the poisonous chemicals, such as mercury and arsenic, that she uses for her magic[[/note]]. This is used to justify her inconsistent power level; when she's the midboss of the Extra Level in ''VideoGame/TouhouKoumakyouTheEmbodimentOfScarletDevil'', she explains beforehand that her asthma has cleared up.
72	* Tyler Chase's little sister Amy is infected with the Deftera GUILT two years prior to the first ''VideoGame/TraumaCenterAtlus'', and [[spoiler:eventually goes into critical condition in Chapter 3. Derek operates on her and cures her, thus removing her status as Ill Girl]].
73	* Miyuki Tanaka from ''VisualNovel/TrueLoveJunaiMonogatari'' is, like Mio, anemic and prone to dizzy spells. She even collapses at some point and [[spoiler: her friend Mikae]] has to take care of her.
74	* ''VideoGame/{{Unpacking}}'': [[spoiler: The protagonist becomes this in 2012 where after her break-up and briefly moving back in her childhood home. She has to use painkillers and a heating pad and in 2013 after getting her own place again, she has a walking cane.]]
75	* Heather the Ghoul from the ''VideoGame/VampireTheMasqueradeBloodlines'' game practically embodies this trope. First, you have to save her life when she lies dying in a hospital. Then, when she finds you again, she acts so cute and affectionate, you just have to have a heart of stone to send her away. Then, she starts making you small presents and other pleasant things, like letting you feed on her blood, free of charge, etc. Most of her behavior is determined by her condition (by turning her into your ghoul, you bind her to yourself and your blood becomes a powerful, addictive drug for her) but that doesn't diminish her cuteness even one bit. That she is a {{Meganekko}} and a potential CosplayOtakuGirl doesn't exactly help, either... [[spoiler: if you ''don't'' send her away, at some point she is gonna be kidnapped and murdered as an act of [[PlayerPunch revenge upon you]].]]
76	* ''VideoGame/AVeryLongRopeToTheTopOfTheSky'': Mint, although, unlike more conventional examples, this doesn't stop her from adventuring with the rest, to the noticeable detriment of her health. Her condition is strongly implied to be genetic (or at least congenital), and the major way it manifests is that she will occasionally just ''collapse'' from too much excitement, strain, or some other strong emotion. [[spoiler:[[KillTheCutie She dies]] [[TearJerker because of this.]]]]
77	-->'''Mint''': ''[to Ivy]'' [[DontYouDarePityMe I told you to stop using me as an excuse!]]
78	* Subverted by Raquel in ''VideoGame/{{Wild ARMs 4}}''. While she's [[spoiler: slowly dying of an unknown disease in her body that's greatly implied to be radiation poisoning]], it doesn't stop her from becoming a badass swordswoman and one of the most powerful characters in the game.
79	* Ellen from ''VideoGame/TheWitchsHouse'' is [[TheHeroine Viola]]'s 7-year-old friend who lives in a house near the woods, and is also terminally ill. The disease gradually eats away at her body, making her look uglier, and her parents are [[ParentalNeglect basically absent from her life]], but Viola cares for her anyway. The plot happens because Viola, on the way to visit her, gets lost and wanders into the titular house. [[spoiler:The sympathetic aspect is subverted, however, when Ellen is revealed as the [[WickedWitch witch]], and a cruel {{sadist}} who screwed over Viola in the backstory in addition to killing [[SelfMadeOrphan her own parents]] and hundreds of innocents over the course of her [[ReallySevenHundredYearsOld immortal life]].]]
80	* ''VideoGame/YesYourGrace'': Paloma, Atana's Queen, has a mysterious illness that she seems to have had had for at least several years. Her husband and son are both desperate to find a cure.
81	* In the ''VideoGame/YumeNikki'' fangame ''[[VideoGame/DotFlow .flow]]'', through the game's symbolism, [[spoiler:it is heavily implied that Sabitsuki, the player character, is dying from some sort of illness]]. This isn't just an EpilepticTree, but almost ''canon''. [[MindScrew Maybe]].
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84	!!Male Examples
85	* [[spoiler: The playable Elektrosoldat]] turns out to be this in ''VideoGame/AkatsukiBlitzkampf''. [[spoiler: The consequences of being both a clone and a member of the MechaMooks "club" include [[BloodFromTheMouth coughing up blood]] (as he does in his ending) and [[WoundThatWillNotHeal being unable to heal properly from any injuries he sustains]].]]
86	* In both ''VideoGame/ArtOfFighting'' and ''VideoGame/TheKingOfFighters'', we have [[{{Bifauxnen}} King]]'s [[PromotionToParent ward and younger brother]] [[AdorablyPrecociousChild Jean]]. His illness is never specified but it's mentioned that he's very delicate and can only walk short distances, so his older sister's main goal is [[HealthcareMotivation to pay for his surgery and later for his treatment]]. He gets noticeably better around ''[[http://www.vgmuseum.com/end/neogeo/a/aof2king.htm AOF 2]]'' ([[spoiler: Robert and Ryo paid for his operation as thanks for King's help when Yuri was kidnapped]]) /[[http://www.vgmuseum.com/end/neogeo/b/kof96gor.htm KOF' 96]] ([[spoiler: he was hospitalized and in treatment as his sister, Mai and Kasumi fought around the world, and the other two girls brought him to King's presence in the end]]).
87	* In ''VideoGame/DarkElfHistoria'', Ruse has always been a bit sickly as a result of the time he spent alone after his parents were killed, but if Fraylia manages to defeat Danny the Orc without failing any previous missions, Ruse will suddenly fall ill with "Neysterbey Syndrome", which requires Fraylia to immediately abandon paid questing in order to go find a cure.
88	* ''VideoGame/EnsembleStars'' has Eichi, who has all the apparent theming for it, having pale blonde hair, a kindly disposition, and constant angel motifs. However, in a total deviation from the trope's usual implications, Eichi is actually a BitchInSheepsClothing who presents an image as a kind BigGood type to the public while secretly sabotaging anyone standing in his way. To a lesser extent, there is also Chiaki who was sickly in his youth and spent a lot of time in hospital (crossing paths with Eichi several times), but who mostly overcame that illness as he grew up. However, he's still very accident prone, and so ends up in the hospital for injuries fairly often.
89	* John Cassidy from ''VideoGame/Fallout2'' suffers from a heart condition, necessitating regular injections of cardio-boosters to keep from having a heart attack. If you give him a chem like Psycho, Buffout, or Jet, it will aggravate the condition to the point of giving him an instant, and fatal, heart attack.
90	* In ''Franchise/FireEmblem'' we have ''many'' cases:
91	** The first one is [[CrutchCharacter Arran]] from ''VideoGame/FireEmblemMysteryOfTheEmblem''. He contracts a [[YourDaysAreNumbered fatal illness]] between ''VideoGame/FireEmblemShadowDragonAndTheBladeOfLight'' and ''Mystery of the Emblem'' and joins Marth's group as [[LastSecondChance his last chance]] [[MyGreatestFailure to atone for a horrible mistake from his past]] before his SoapOperaDisease catches up with him.
92	** Then there's [[spoiler:Prince Julius of Velthomer/Grannvale]] from ''VideoGame/FireEmblemGenealogyOfTheHolyWar''. In ''VideoGame/FireEmblemThracia776'' he catches a high fever, and a conversation between [[spoiler:his half-brother Saias and girlfriend Ishtar]] states that while he was somewhat delicate as a child, his health really declined after [[spoiler:he became the vessel for the Dark God Loptous.]]
93	** In ''VideoGame/FireEmblemTheBindingBlade'', [[MagicMusic Elffin]] [[spoiler:aka Prince Mildian]] has really bad eyesight. [[spoiler:He once was poisoned to near death, and this partial blindness is the only effect that still remains.]]
94	** ''VideoGame/FireEmblemTheBlazingBlade'':
95	*** Subverted by Lucius, who is said to be pale and sickly. His companion Raven asks him once in a while if he's "under the weather", and he apparently has a borderline seizure in his C support with [[spoiler: Renault]], who also shows worry for his well-being. However, Lucius himself says it's not a physical illness, but one "from the soul". (It ''could'' be clinical depression or PTSD, as he says he tries to help others with their pain yet he is afflicted too.)
96	*** Played straight by Nils. At some point he ''does'' have a seizure and collapses, and his [[PromotionToParent older sister Ninian]] asks the group not to move him from the spot he passed out on. The following mission has protecting him for 15 turns as its goal.
97	** Despite being a [[BadassBookworm genius-level]] [[CastingAShadow dark magic user]], Prince Lyon of Grado from ''VideoGame/FireEmblemTheSacredStones'' has a very weak constitution that causes him to feel inferior to his best friends, Ephraim and Eirika, and his stern but gentle father Emperor Vigarde.
98	** In ''VideoGame/FireEmblemPathOfRadiance'', local [[WhiteMagicianGirl White Magician Guy]] Rhys appears to constantly suffer from one illness or another, with several characters inquiring about his health.
99	** In the aforementioned Henry's supports with Olivia in ''VideoGame/FireEmblemAwakening'', he claims his bloodlust is a genetic nervous disorder. Whether it actually ''is'' or not, eh, it's something else. His profile, on the other hand, says that he actually has [[http://en.wikipedia.org/wiki/Low_blood_pressure hypotension aka low blood pressure]], which can potentially be quite serious.
100	* ''Growlanser II: The Sense of Justice'' has a female character whose younger brother is an ill boy. And yes, there is a mysterious "operation" that can cure him, and this provides that character's main motivation. In a slight variation on the usual plot, the character's family is very wealthy and can easily afford the operation, but the Ill Boy is afraid to go through with it because it is reputed to be extremely painful. (Maybe the MagiTek of the setting doesn't include anesthetic?)
101	* ''VideoGame/HarvestMoon'':
102	** Marlin from ''VideoGame/HarvestMoonAWonderfulLife'' and ''VideoGame/HarvestMoonDS'' was ill in his youth. He was moved out into the mountains in the hope that the HealthyCountryAir would cure him. It did help quite a bit, but he's still kinda sickly.
103	** In stark contrast with his boisterous and muscular adult self, Dean from ''VideoGame/HarvestMoonLightOfHope'' was a sickly child who spent much of his time indoors. He loved reading books about flowers so he begged his dad to take him hiking with him. Over time, the frequent hikes helped Dean become healthier.
104	* Daniel Curien, son of Dr. Roy Curien (an antagonist in the ''VideoGame/HouseOfTheDead'' series) was overcome with an illness during his childhood days. Dr. Curien stepped beyond the boundaries, just to save his son's life.
105	* In ''VideoGame/TheLegendOfZeldaTwilightPrincess'', Prince Ralis of the [[FishPeople Zora]] is first encountered gravely ill due both to being attacked by Zant's forces on his way to seeking help from Princess Zelda and to being dehydrated from being away from water too long. Link must escort Telma and Ilia as they take Ralis to Kakariko Village to be healed by the shaman there.
106	* In ''VideoGame/LikeADragonInfiniteWealth'', while Kiryu has never been delicate, he's revealed to have cancer. Despite that, he's still as good-looking as ever.
107	* In ''VideoGame/MassEffect2'', assassin Thane Krios suffers from a condition called Kepral's syndrome, which many drell get since the comparatively moist environments non-drell inhabit causes their lungs, which are more accustomed to their homeworld's arid atmosphere, to gradually lose the ability to draw in oxygen. As a result of his condition, Thane joins Shepard's SuicideMission readily: regardless of whether he joins, he may not have long to live.
108	** A series-wide example would be the quarians, who cannot survive outside of their suits as they have a rather weak immune system, which was even further weakened by three centuries of living aboard sterile spaceships. [[spoiler: they get better if you manage to [[GoldenEnding get them to make peace with the geth during ''Priority: Rannoch'']] and then choose the "Synthesis" or "Control" ending in ''VideoGame/MassEffect3'' : since the geth do not believe in holding grudges, they welcome their quarian creators back to Rannoch with open arms and upload themselves to the quarians' suits to mimic a variety of diseases and illnesses. As a result, quarians are able to ditch the suits completely ''within a few years'' following the events of the trilogy]].
109	* In ''VideoGame/MegaManBattleNetwork 3'', a kid named Mamoru has an illness with a vague acronym (HBD) that essentially boils down to a heart defect. Lan helps the kid out and convinces him to go through another operation that is supposed to cure it [[spoiler: because it just happens to be the disease that killed Lan's twin brother Hub, whose mind was digitized and placed inside Megaman.EXE]]. The hospital just has to be attacked on the day of the operation, and it's up to Lan to save everybody, including the kid.
110	* From what little we see of [[spoiler: Hugo]] in ''VideoGame/{{OFF}}'', he seems to be this. His [[VoiceGrunting voice grunting]] is a cough, and exploring The Room shows writing that mentions having to take pills. There's also all the brain and coma imagery in the battles, items, and game over screen, but that's going into WMG territory.
111	* Akinari Kamiki, the Sun Arcana from ''VideoGame/Persona3'', is a prospective writer who was born ill, thus his days have been numbered ever since birth. Developing his S-Link is about having him learn to enjoy his last days of life. [[spoiler: He will die before the game is over, leaving the children's book he wrote with the MC's help and encouragement as a TragicKeepsake, and if his link is maxed his soul will cheer on you before you take on Nyx.]]
112	** From the same game is party member [[HiddenHeartOfGold Shinjiro Aragaki]], who is slowly dying courtesy of suppressants that he's taking to suppress his Persona. It has degraded his immune system to the point that he gains a nasty IncurableCoughOfDeath and, according to WordOfGod, his body cannot regulate its body temperature properly anymore (this was given as an explanation as to why he always wears winter clothing during Spring and Summer.)
113	* Wally/Mitsuru, TheRival from ''VideoGame/PokemonRubyAndSapphire'', is mentioned to be rather sickly and weak-bodied as well. Apparently, he has asthma.
114	* Similar to the above, Hanbei from ''VideoGame/PokemonConquest'' suffers from tuberculosis (not like the game will state that). Unlike the above example, he keeps it to himself and does what Hideyoshi tells him to do, so at the end of his episode, he starts coughing. When asked what's wrong, Hanbei responds that he got too excited; Kanbei doesn't believe it one bit. In both cases, the disease eventually killed the real-life Hanbe Takenaka.
115	* Subverted: Ukyo Tachibana from ''VideoGame/SamuraiShodown'' has tuberculosis (IncurableCoughOfDeath and BloodFromTheMouth included), but he remains quite a badass fighter. [[spoiler: Further subverted as the second game implies that he dies of it, but he reappears in the third (which admittedly can be excused as being a prequel).]] Amusingly, his [[PressXToDie Seppuku]] sees him cough and then collapse, as the TB finally finishes the job.
116	* [[WhiteHairBlackHeart Hanbe Takenaka]] from ''VideoGame/SengokuBasara'' is a villainous version of this, as he spends most of his time proving just how [[EvilerThanThou evil he is]] through sheer [[MagnificentBastard manipulation]] and [[KickTheDog dog-kicking]] despite his [[IncurableCoughOfDeath tuberculosis]].
117	* After regaining the memories of their true identity in ''VideoGame/SuperRobotWarsX'', [[spoiler:Iori]] revealed to X-Cross members that they were originally someone who was physically weak, and prone to sickness. Which greatly surprised the X-Cross members.
118	* Ion from ''VideoGame/TalesOfTheAbyss'' is known to have a weak constitution, and upon using a Daathic fonic arte, becomes weak to the point of collapsing. [[spoiler:This is actually because the Ion seen in the game is a replica of the original Ion, who died a few years prior. Doing things such as using fonic artes or reading the Score cause Replica Ion's body to degenerate.]]
119	* In ''VideoGame/TalesOfBerseria'', Velvet's younger brother Laphicet is rather sickly and often bedridden. ...Well, he ''was'', until Artorius killed him. A sidequest reveals [[spoiler:his illness was called the Twelve Year Sickness, inflicted progressively worse fevers on him every twelve days, and would have killed him anyway on his twelfth birthday]]. A late-game WhamEpisode reveals [[spoiler:he ''knew'' this, and volunteered to be Artorius' human sacrifice]].
120	* Emilio Juarez from ''VideoGame/{{Trauma Center\|Atlus}}: Under the Knife 2'', who is [[spoiler:one of the Sinners (read: tortured orphans used by the bioterrorist organization Delphi as lab rats) saved by Derek in the first game]] is seventeen, yet manages to be an excellent example of an Ill Boy all the same. If it weren't for all the "he"s and "boy"s used referring to him, though, it probably wouldn't be hard to [[DudeLooksLikeALady mistake him for a more traditional example of the trope]].
121	* Saki in ''VideoGame/UncommonTime''. It's subverted in that he's still capable of going adventuring with the heroes, but he's still very frail and sickly, and sometimes collapses and has to be taken care of. [[spoiler:This is in fact very serious; he is terminally ill with a congenital disease and knows he's likely to die soon. He keeps this a secret from the others, but his LoveInterest Meirin finds out anyway. In the GoldenEnding, she promises to find a cure for him; in one of the bad endings, he chooses to commit suicide rather than let the disease catch up to him.]]
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123	----
124	!!Mixed Examples
125	* ''VideoGame/DragonQuestV'': Mr. Whitaker is always sick, recovering from being sick or coming down with a new sickness. Taking care of him is the reason that his daughter Bianca can't be an adventurer, as much as she'd like to. Before the Hero comes along at least.
126	* Throughout the ''VideoGame/GodOfWar'' series, both of Kratos's children were ill.
127	** Calliope was a rather sickly child and Kratos went on a quest for Ambrosia to help her condition.
128	** In ''VideoGame/GodOfWarPS4'', Atreus suffers from some kind of debilitating condition that manifests as IncurableCoughOfDeath for most of his life. Mimir suggests that the illness is [[spoiler: psychosomatic, a result of Atreus' struggle to reconcile his divine nature and emerging abilities.]]
129	* The ''VideoGame/GuiltyGear'' franchise gives us a female example and a male one [[spoiler: who's a subversion]]:
130	** Female Example: Marina from the ''Ride the Lightning'' novel, a wheelchair-bound young lady who is the sister of [[spoiler: Solaria, a woman who was horribly experimented on and turned into a Gear -- which could have happened to Marina, too]]. She then accidentally drinks a drug named Vitae, which cures her disability [[spoiler: but in fact is made of Gear cells, which start causing her '''massive''' BodyHorror. She ''barely'' survives thanks to Ky and others, and later is reunited with Solaria and given the protection they both need, but [[AnArmAndALeg loses both of her legs]] and has to return to her wheelchair.]]
131	** Male Example: Bedman, a comatose young boy piloting a sort of hybrid between a MiniMecha and a bed. He's been subjected to horrible experiments that allow him to trap people in nightmare worlds of his own creation. [[spoiler: Subverted in that he is actually a ''villain'' -- more exactly an agent of the Senate, the driving force behind Ky's appointment as a PuppetKing, amongst other things.]]
132	* The quarians from ''Franchise/MassEffect'' are a ''species'' of Ill People. Since their forced exile from their homeworld 300 years before the events of the games, quarian immune systems (which were already weaker than those other species) have deteriorated to the point that all quarians must wear [[LatexSpaceSuit environmental suits]] at all times just so they don't die. ''Every'' quarian Shepard meets in the games -- from WrenchWench party member Tali'Zorah to badass marine Kal'Reegar to the valley girl complaining about her boyfriend on Illium -- is one suit breach away from potentially deadly sickness. That said, [[DontyouDarePityMe they don't appreciate the stereotype:]]
133	--> "I'm not gonna die from an infection in the middle of a battle. That's just insulting!”
134	* The main characters of ''VisualNovel/{{Narcissu}}'' are a terminally ill boy and girl. The prequel adds two more ill girls to the cast, one of them an [[LittlestCancerPatient 8-year-old orphan.]] And the third game... just say the whole series revolves around this trope.
135	* ''VideoGame/{{Undertale}}'''s Neutral path explains that the AmbiguousGender First Human was adopted by Asgore and Toriel after they fell into the Underground, but one day fell ill and died, after which their adoptive brother Asriel absorbed their SOUL in a fit of grief, took their body into the nearby human village, and was killed by the inhabitants who believed Asriel was responsible for their death. This lead to Asgore swearing revenge against humanity, a plan that disgusted Toriel so much she left the kingdom to live in the Ruins. Very tragic. Which makes it hit harder in the True Pacifist path, when you learn that [[spoiler:they actually poisoned themself on purpose as a ThanatosGambit. They told Asriel that the plan was to leave the barrier (which requires the amount of power in a human SOUL plus a monster SOUL), kill just six more humans, and return to shatter the barrier (which requires the amount of power in seven human [=SOULs=]), thereby freeing monsterkind. It's not made clear whether they were lying all along, or just got DrunkWithPower, but when it came time to execute the plan, Chara wanted to exterminate the entire village, and possibly all of humanity. Asriel's willpower was able to stop them, but got him killed as he refused to fight back.]]
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Context DelicateAndSickly / VideoGames