History Tearjerker / BabylonFive

** ... where he knows what's coming to Londo, and he's genuinely sad for what awaits this man he remembers since his (Londo's) childhood. And then later, the Drakh (Shiv'kala) punishes him through the Keeper for giving what can hardly be seen as even a ''hint'' of a revelation of what was going on to Londo--and if you've read The Centauri Trilogy you know that these Keepers can be used to inflict a great amount of pain on their hosts.

* For all that a lot of people hate Lochley, Creator/NeilGaiman gave her one of the most tear jerking moments in the entire series in the ''Day of the Dead'' episode: she is confronted by the "ghost" of her dead friend Zoe, who OD'd decades earlier when they were teenage drug addicts, and whose body Lochley found (and never knew whether the OD was an accident or suicide). Just three simple words, and it will break you in half, just like it does Zoe:

** What makes it even worse is that, until that moment, Zoe ''didn't really believe she was dead!'' She'd even asked Lochley if she had any "junk" around earlier.

** especially the scene between Delenn and Lennier where she describes growing up in in capital city, the thinks of her "beautiful city in flames." Even more so when you consider the actress that played her came from a country that was going through a bloody civil war around the time the show originally aired (and that JMS admitted that fact informed his plotting of the series).

* Londo in "Acts of Sacrifice". He has more influence and power than he's ever had before, but no real friends to share it with.
-->'''Londo''': ''I want you to stay! And have a little drink with me. I want you to be happy, I want '''me''' to be happy. I want you to be happy for me and me to be happy for you. Is that so much to ask around here? Why is everyone here walking around like they are afraid of me?''
-->'''Garibaldi''': ''[[BrutalHonesty Maybe we are]].''

*** Made especially poignant when you realise that she's asking for the ultimate sacrifice of tens of thousands of people on the minute, off chance that a few hundred people may be saved. That even with the best possible outlook, mankind will be decimated anyway.

** It gets worse when you remember why they were out there. Earthforce was helping an alien government suppress a rebellion in exchange for basing rights, gaining Earth a forward defence-outpost in case of conflict with the Centauri Republic... but at the end of the season, the Alliance signs a ''non-aggression pact'' with the Centauri, meaning that those Gropos' sacrifice was for ''nothing''.
* Or how about Sheridan touching the screen with his wife's face on it at the end of the episode where his sister visits and saying "Goodbye, Anna. I love you." So..very..poignant. Must..get..tissues. He forgot to say that the last time they spoke, and always regretted it. In Season 3 she shows up again, but she's not really Anna any more.

* The very end of "Endgame" (and the resulting personal aftermath). Marcus Cole, trying to save the life of what he thought was his pretty much unrequited love, bludgeons his way through the medlab so he can resuscitate her with an artifact (that, incidentally, needs to drain his life to work its magic). The nearly-dead Marcus whispers a faint "I love you" over the still unconscious Ivanova.

* While it was not something that is on the show, JMS' introduction on the Season Five DVD booklet as he explains the odds the show overcame to become what is was, especially the final words.

-->'''Neroon''':I was born Warrior Caste! But I see now, the calling of my heart is RELIGIOUS! The war is over! Listen to her! Listen!

* The end of "Intersections in Real Time". Sheridan has been tortured, interrogated, beaten, the inquisitor has done everything within his power to break him but he has said no. After he refuses his "last chance" to recant and join Clark, they strap him to a bed and take him to "Room 17", with a priest reading the last rites as they go... and then in Room 17 they reveal a chair identical to the one he'd been strapped into, and a new inquisitor comes in to start it all over again. What's worse, the Drazi he "convinced to stay strong" was working with them the whole time. The look on Sheridan's face is heartbreaking.
* Ivanova's utter despair in "The Hour of the Wolf", when she believes they've lost Sheridan forever. It takes a special touch to make the story of a friendship just as beautiful and just as moving as the story of a romance, but JMS did it ''perfectly'' with John and Susan; she's reduced to total heartbreak, and if anyone ever wondered just how much those two mean to each other, they certainly can't any more.

* Delenn and G'Kar's discussion right before the latter joins the war council.

* [[http://www.epictimes.com/07/28/2016/j-michael-straczynskis-statement-death-jerry-doyle/ J. Michael Straczynski's]] thoughts on the passing of actor Jerry Doyle (who played Garibaldi).