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* ''WesternAnimation/TheBeagles'': [[WesternAnimation/{{Underdog}} Simon Barsinister and Savoir-Faire]] are canine musicians during UsefulNotes/The60s who perform groovy music. Their boss is [[WesternAnimation/PinocchiosChristmas Santa Claus]].
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!!#0-9
* ''WesternAnimation/OneHundredAndOneDalmatiansTheSeries'': [[WesternAnimation/KingOfTheHill Bobby Hill]], [[WesternAnimation/{{Rugrats}} Phil]] [[WesternAnimation/AllGrownUp DeVille]], [[WesternAnimation/SonicTheHedgehogSatAM Sally Acorn]], and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]] go on adventures, usually thwarting the plans of [[WesternAnimation/{{Recess}} Miss Finster]]. Other foes tend to be [[WesternAnimation/XiaolinShowdown Clay Bailey]] and [[WesternAnimation/PepperAnn Milo]]. [[WesternAnimation/TheBuzzOnMaggie Pupert]], WesternAnimation/{{Dexter|sLaboratory}}, and [[WesternAnimation/XiaolinShowdown Omi]] (who left the gang after falling in love with Bobby) are all in Milo's gang. Bobby is rivals with [[WesternAnimation/{{Recess}} King Bob]]. [[WesternAnimation/HeyArnold Harold Berman]] is friends with the pups as well. They are all in the Bark Brigade, run by [[WesternAnimation/MightyDucksTheAnimatedSeries Duke L'Orange]], [[WesternAnimation/ThePowerpuffGirls1998 Ace]], and [[WesternAnimation/GoofTroop Pete]].
* ''WesternAnimation/TwoStupidDogs'': [[Film/AmericanReel Marvin Ayres]] and [[WesternAnimation/ABugsLife Dim]] are two moronic canines who have many misadventures together, often running afoul of [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Nick Dean]] and [[WesternAnimation/TomAndJerryKids Clyde Cat]]. [[WesternAnimation/{{Animaniacs}} Yakko Warner]] is a close friend of theirs, while [[Film/TransformersFilmSeries Ironhide]] and [[WesternAnimation/{{CatDog}} Cat]] are [[WesternAnimation/SecretSquirrel secret agents that star in a spy cartoon]] that airs between episodes.
* ''WesternAnimation/ThreeTwoOnePenguins'': When [[Series/{{Smallville}} Phillip Lamont]] and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Sweetie Belle]] move in with their grandmother [[WesternAnimation/XMenEvolution Destiny]], they find four porcelain penguins that turn out to be [[Manga/{{Inuyasha}} Rasetsu]], [[VideoGame/MarvelVsCapcom3 Shuram-Gorath]], WesternAnimation/{{George of the Jungle|2007}}, and [[Manga/DragonBall Master Roshi]]. Together, they fend off various villains.
* ''WesternAnimation/ThreeAmigonauts'': [[WesternAnimation/CaptainFlamingo Ruth Ann]], [[WesternAnimation/CupcakeAndDinoGeneralServices Mayor Vicky]], and [[WesternAnimation/ClangInvasion Socket]] go to a school for space cadets. [[WesternAnimation/TotalDrama Mike]] is their rival, while [[WesternAnimation/{{Mysticons}} Baron Dreadbane]] is the trio's vehicle.
* ''WesternAnimation/{{Sixteen}}'': [[ComicBook/{{Diabolik}} Eva Kant]], WesternAnimation/ScaredySquirrel, [[Series/DegrassiTheNextGeneration Officer Turner]], [[Series/DropDeadDiva Deb Dobkins]], [[WesternAnimation/RubyGloom Iris]] and [[WesternAnimation/{{Sidekick}} Trevor Troublemeyer]] hang out in a mall. Eva works for [[WesternAnimation/TimothyGoesToSchool Henry]] at a sporting goods store; Trevor dates [[WesternAnimation/CarlSquared Chloe Crashman]] for a time; Turner dates [[WesternAnimation/GirlstuffBoystuff Reanne]] and then [[WesternAnimation/JaneAndTheDragon Verbena]]; [[WesternAnimation/TimeWarpTrio Sam]] hits on Iris but later dates [[WesternAnimation/TotalDramaPresentsTheRidonculousRace Emma]]; Iris also works for [[WesternAnimation/AlmostNakedAnimals Bunny]] and [[WesternAnimation/TotalDrama Katie and Sadie]]; [[WesternAnimation/{{Birdz}} Tommy Turkey]] is Trevor and Turner's boss in Season 2; [[WesternAnimation/PeepAndTheBigWideWorld Quack]] is the mall cop; and [[Series/SchittsCreek Jocelyn Schitt]] is Deb's rival.
* ''WesternAnimation/The7D'': [[WesternAnimation/{{Amphibia}} Hop Pop]], [[WesternAnimation/WolverineAndTheXMen2009 Blob]], [[WesternAnimation/GravityFalls Sheriff Blubs]], [[WesternAnimation/{{Futurama}} Phillip J. Fry, Kif Kroker]], [[WesternAnimation/WhereonEarthisCarmenSandiego Zack]], and [[WesternAnimation/PhineasAndFerb Perry the Platypus]] protect [[WesternAnimation/BackAtTheBarnyard Abby the Cow]]'s kingdom from the evils of [[WesternAnimation/PetAlien Swanky]] and [[Series/DropDeadDiva Joyce Keck]]. [[Creator/OneSaturdayMorning Manny the Uncanny]] is Abby's hapless assistant, and [[WesternAnimation/TheFairlyOddParents the Crimson Chin]] and [[Series/StarTrekTheNextGeneration Guinan]] are magical objects. Abby's great grandmommers is [[Film/SinginInTheRain Kathy Selden]].
!!A
* ''WesternAnimation/AaahhRealMonsters'': [[WesternAnimation/TinyToonAdventures Buster Bunny]], [[WesternAnimation/DarkwingDuck Gosalyn Mallard]], and [[WesternAnimation/{{Rugrats}} Reptar]] go to a school for monsters run by [[VideoGame/Spyro2RiptosRage Ripto]] to learn how to scare people. [[WesternAnimation/HeyArnold Coach Wittenburg]] tries to prove the monsters are real, while [[WesternAnimation/TheWildThornberrys Nigel Thornberry]] criticizes Ripto's teaching skills.
* ''WesternAnimation/AbbyHatcher'': [[WesternAnimation/MaxAndRuby Ruby]], the daughter of [[Series/{{Salvation}} Karissa]] and [[WesternAnimation/{{Sixteen}} Jonesy Garcia]], has adventures around her parents' hotel with magical creatures called Fuzzlies, of which one named [[WesternAnimation/ElinorWondersWhy Ari]] is her best friend.
* ''WesternAnimation/ActionMan2000'': [[VideoGame/FatalFury Terry Bogard]] is an Extreme sports athlete with analytical powers, who, along with his friends, [[Anime/PowerpuffGirlsZ Mojo Jojo]], [[WesternAnimation/TheCrampTwins Mari Phelps]] and [[WesternAnimation/EdEddNEddy Rolf]], and his high school coach, [[Series/StargateSg1 Teal'c]], and his friend/rival, [[Film/TuckerAndDaleVsEvil Dale]] must battle against the council of Doom consisting of its leader, [[WesternAnimation/XMenEvolution Beast]], later [[WesternAnimation/TheNewAdventuresOfHeMan Skeletor]], [[Manga/DragonBall Dende]], [[WesternAnimation/EdEddNEddy Sarah]], and [[Anime/UnicronTrilogy Optimus Prime]].
* ''WesternAnimation/TheAddamsFamily1992'': [[Film/AttackOfTheKillerTomatoes Professor Mortimer Gangreen]] and [[WesternAnimation/{{Duckman}} Merv's Secretary]] live a rather creepy and kooky life with their children [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Jimmy Neutron]] and [[WesternAnimation/TheOblongs Beth Oblong]], uncle [[WesternAnimation/TomAndJerryTheMovie Captain Kiddie]], cousin [[WesternAnimation/TeenageMutantNinjaTurtles1987 Krang]], butler WesternAnimation/DarkwingDuck, and grandmother [[WesternAnimation/Thumbelina1994 Ms. Fieldmouse]]. Their neighbors are [[WesternAnimation/DannyPhantom Jack Fenton]], [[WesternAnimation/Frozen2013 Gerda]], and [[WesternAnimation/DaveyAndGoliath Davey Hansen]].
* ''WesternAnimation/AdventureTime'': [[WesternAnimation/BatmanTheBraveAndTheBold Young Robin]] and his best friend [[WesternAnimation/{{Futurama}} Bender]] go on various adventures with Princess [[WesternAnimation/TeenTitans2003 Starfire]] and battle evil foes like [[WesternAnimation/UltimateSpiderMan2012 Dr. Octopus]], [[WesternAnimation/PhineasAndFerb Vanessa Doofenshmirtz]], and [[WesternAnimation/AvatarTheLastAirbender Fire Lord Ozai]].
** Starfire's servant is [[WesternAnimation/CampLazlo Chip/Skip]].
** At the end of the second season, Starfire gets possessed by [[WesternAnimation/TeenTitans2003 Slade]] and turns into [[WesternAnimation/TeenageMutantNinjaTurtles2012 Shredder]]. After Robin and Bender exorcise her, she regresses into [[Series/BetterOffTed Rose Crisp]].
** ''[[GenderFlip Adventure Time with Fionna and Cake]]'': [[Series/{{Californication}} Becca Moody]] and her cat [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Bubbie]] have to save Prince [[Series/HowIMetYourMother Barney Stinson]] from [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Mandy]]. [[Film/SoloAStarWarsStory Young Lando Calrissian]] is a mischievous vampire.
** At the end of season 3, Robin has a crush on the daughter of [[VideoGame/DissidiaFinalFantasy Chaos]], [[VideoGame/ResonanceOfFate Leanne]].
** In an alternate universe, Robin's mother is WesternAnimation/{{Mulan}}, and his future self is [[WesternAnimation/{{Gargoyles}} Xanatos]].
** Towards the end of season 3, [[WesternAnimation/KickButtowski Jackie Wackerman]] falls in love with [[WesternAnimation/RegularShow Benson]].
** WesternAnimation/RickAndMorty are demented dukes, though the younger one is much nicer than the older one.
** [[Series/{{Scrubs}} Turk]] just really wants to be a princess.
** [[Series/StarTrekTheOriginalSeries Mr. Sulu]] wants Starfire to love him ''or else''.
** [[Series/TheOfficeUS Dwight]] is a robot swordsman and an out-classed white mage; Creed is a wandering adventurer.
** At the start of season 6, it turns out that [[spoiler:Robin's dad is]] [[WesternAnimation/KingOfTheHill Bill Dauterive]].
** [[Series/{{Girls}} Hannah Horvath]] literally wrote the book on portals.
** An Film/{{Orphan}} is a one-armed bandit from the past-turned gooey glowing green ghost [[spoiler: and one of Robin's past lives]].
** [[Film/XMenFilmSeries (Older) Mystique]] is TheVamp[=iest=] of a quintet of vampires.
** [[WesternAnimation/TheAmazingWorldOfGumball Anais]] is an assassin.
* ''WesternAnimation/AdventuresFromTheBookOfVirtues'': [[WesternAnimation/RandyCunninghamNinthGradeNinja Viceroy]], [[Franchise/ScoobyDoo Fred Jones]], [[WesternAnimation/TazMania Taz]], and [[WesternAnimation/DextersLaboratory Dexter's Mom]] help [[WesternAnimation/TheOblongs Milo Oblong]] and [[WesternAnimation/{{Futurama}} Cubert Farnsworth]] solve everyday kid problems by reading stories to teach them important lessons.
* ''WesternAnimation/TheAdventuresOfChuckAndFriends'': [[WesternAnimation/PegPlusCat Jesse]] is a young dump truck whose parents are [[WesternAnimation/PawPatrol Mr. Porter]] (later [[WesternAnimation/RubyGloom Len]]) and [[Film/DumbAndDumber Mary Swanson]] and older brother is [[Anime/{{Bakugan}} Masquerade]]. His friends include WesternAnimation/RobTheRobot, [[WesternAnimation/{{Detentionaire}} Camillio Martinez]], [[WesternAnimation/CampLakebottom Squirt]], [[WesternAnimation/SevenLittleMonsters One]], and [[WesternAnimation/TimothyGoesToSchool Fritz]].
* ''WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius'': Manga/ZatchBell is a boy genius who created his pet, [[WesternAnimation/{{Hercules}} Pegasus]]. His best friends are [[WesternAnimation/DextersLaboratory Major Glory]] and [[WesternAnimation/CloneHigh Jesús Cristo]]. [[WesternAnimation/SpongebobSquarepants Sandy Cheeks]] and [[WesternAnimation/ThePJs Calvin]] usually mock Zatch's work, while [[WesternAnimation/EvilConCarne Hector Con Carne]] is a CloudCuckoolander and [[WesternAnimation/ChalkZone Snap]] is the BadButt [[TheChewToy Chew Toy]]. [[Series/WizardsOfWaverlyPlace Cupid]] and [[WesternAnimation/TheMightyB Hillary Higgenbottom]] are Zatch's parents, [[WesternAnimation/KimPossible Mrs. Stoppable]] is their teacher, [[WesternAnimation/TimeSquad Buck Tuddrussel]] is their principal, [[WesternAnimation/SonicTheHedgehogSatAM Sally Acorn]] is a girl Zatch has a crush on, [[Franchise/WinnieThePooh Tigger]] is a superhero that Jesús idolizes (with [[VideoGame/MetalGearSolid Grey Fox]] being Tigger's archnemesis), and [[WesternAnimation/TheRenAndStimpyShow Stimpy]] is the local candy bar owner.
** Occasionally, Zatch, Pegasus, Major Glory and Jesús, often accompanied by Sandy and Calvin, have to fend off threats such as the evil alien [[VideoGame/KidIcarusUprising Hades]] (formerly [[Series/StarTrekTheNextGeneration Captain Picard]]) and his henchman [[VideoGame/YokaiWatch Mangimutt]] (formerly [[WesternAnimation/TreasurePlanet B.E.N.]]), [[WesternAnimation/TheWildThornberrys Nigel Thornberry]], a scientist who could never finish anything, his daughter [[WesternAnimation/TheOwlHouse Eda]], Zatch's failed nanobots [[WesternAnimation/TheFairlyOddparents Cosmo]] and [[WesternAnimation/TransformersAnimated Starscream]], intergalactic game show host [[Franchise/ToyStory Buzz Lightyear]], space bandits [[WesternAnimation/MyLittlePonyFriendshipIsMagic Chancellor Neighsay]], [[WesternAnimation/CampLazlo Raj]] and [[WesternAnimation/MyLifeAsATeenageRobot Armaggedroid]], junk salesman [[WesternAnimation/CowAndChicken Red Guy]], SpoiledBrat [[WesternAnimation/TeenageMutantNinjaTurtles2012 Donatello]], evil baby [[Series/{{Seinfeld}} Alec Berg]], brainwashing granny [[WesternAnimation/TheLittleMermaid1989 Carlotta]], and MadScientist [[WesternAnimation/{{Animaniacs}} Baloney the Dinosaur]].
** ''WesternAnimation/PlanetSheen'': After borrowing one of Zatch's rockets, Jesús crash-lands on Planet Zeenu, which is ruled by emperor [[Manga/{{Naruto}} Gato]]. He also befriends a chimpanzee who crashed on the planet years ago named [[WesternAnimation/{{Chowder}} Mr. Fugu]], meets an alien named [[WesternAnimation/PinkyAndTheBrain Pinky]], [[SuspiciouslySimilarSubstitute who is almost exactly like Major Glory]], falls in love with Series/PunkyBrewster, and keeps away from [[WesternAnimation/FostersHomeForImaginaryFriends Coco]], the two-faced daughter of the emperor. Meanwhile, [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Peppermint Larry]] schemes to kill Jesús, along with his sidekick [[Film/TheHitchhikersGuideToTheGalaxy2005 Eddie the shipboard computer]].
* ''WesternAnimation/TheAdventuresOfPussInBoots'': [[WesternAnimation/WabbitALooneyTunesProduction Pepé Le Pew]] protects the village of San Lorenzo, which is inhabited by [[Film/EpicMovie Lucy]], [[WesternAnimation/TheLionGuard Bunga]], [[WesternAnimation/FostersHomeForImaginaryFriends Coco]], [[WesternAnimation/WhatsNewScoobyDoo Daphne Blake]], and WesternAnimation/{{Freakazoid}}. The mayor is [[WesternAnimation/CampLazlo Lazlo]].
* ''WesternAnimation/TheAdventuresOfSamAndMaxFreelancePolice'': [[WesternAnimation/TheSuperMarioBrosSuperShow King Koopa]] and [[WesternAnimation/{{Pelswick}} Pelswick Eggert]] work as private investigators. Their allies include their mysterious agent [[WesternAnimation/LittleBear Father Bear]], pint-sized genius Anime/SailorMoon, and an extremely clingy fan of the duo named [[Series/TheRedGreenShow Harold Green]].
* ''WesternAnimation/AdventuresOfSonicTheHedgehog'': [[Series/FamilyMatters Steve Urkel]] is a speedy hedgehog who works with his friend [[Series/{{Rubicon}} Grant Test]] to stop the schemes of [[WesternAnimation/ReBoot Old Man Pearson]] and his minions [[Manga/ZatchBell Professor Takamine]], [[WesternAnimation/BeastWars Optimus Primal]], and [[Manga/DragonBall Goku]]. [[Manga/InuYasha Suikotsu]] tries to sell them stuff. Old Man Pearson was [[Franchise/WinnieThePooh Tigger]] in the pilot.
* ''WesternAnimation/AdventuresOfTheGummiBears'': A group of bears, consisting of [[WesternAnimation/WackyRaces Dick Dastardly]], WesternAnimation/GeorgeOfTheJungle (later [[WesternAnimation/HouseOfMouse Ludwig Von Drake]]), [[WesternAnimation/LooneyTunes Witch Hazel]], ComicStrip/{{Garfield}}, [[WesternAnimation/MuppetBabies1984 Baby Rowlf the Dog]], and [[WesternAnimation/TheSmurfs1981 Slouchy Smurf]], help a squire who is initially [[Music/TheAquabats The MC Bat Commander]] (but later becomes [[WesternAnimation/TheLegendOfKorra Mako]], then [[WesternAnimation/TheFairlyOddParents Chester McBadbat]], and finally [[WesternAnimation/TaleSpin Kit Cloudkicker]]) defend his home kingdom from a pack of ogres led by Radio/TheLoneRanger. [[WesternAnimation/TheLionKing1994 Adult Simba's singing voice]] sings the theme song.
* ''WesternAnimation/TheAdventuresOfTintin1991'': [[Anime/SailorMoon Andrew Foreman]] is a young reporter who goes on adventures with his pet [[WesternAnimation/{{Birdz}} Eddie Storkowitz]], sea captain [[WesternAnimation/XMenTheAnimatedSeries Master Mold]], AbsentMindedProfessor [[Series/TheRedGreenShow Mike Hamar]], and twin detectives [[WesternAnimation/TheAdventuresOfSuperMarioBros3 Bully Koopa and Toad]].
* ''WesternAnimation/AladdinTheSeries'': [[Series/FullHouse Steve Hale]] is a street urchin engaged with Princess [[Film/{{Joshua}} Karen Danforth]]. The two go on adventures with their companions [[WesternAnimation/TheSimpsons Barney Gumble]], [[WesternAnimation/{{Cyberchase}} Digit]], and WesternAnimation/CuriousGeorge, fighting villains such as [[WesternAnimation/ThePowerpuffGirls Fuzzy Lumpkins]], [[WesternAnimation/{{Dilbert}} Catbert]], [[WesternAnimation/CowAndChicken Chicken]], [[WesternAnimation/TaleSpin Baloo]], [[WesternAnimation/{{Rugrats}} Chas Finster]], and [[Series/{{Cheers}} Lilith Sternin]]. [[Film/{{Ladybugs}} Matthew]] ([[WesternAnimation/CampLazlo Raj]] in one episode) is an evil wizard and [[ShadowArchetype Steve's opposite]]. [[Series/StarTrekDeepSpaceNine Odo]] is an Egyptian-themed Imp and conman.
* ''Literature/AlexanderAndTheTerribleHorribleNoGoodVeryBadDay'' [- (1990 AnimatedAdaptation) -]: [[WesternAnimation/TheMagicSchoolBus Arnold Perlstein]] has a terrible day. [[Theatre/ThePhantomOfTheOpera Raoul de Chagny]] and [[Film/SleeplessInSeattle Loretta]] are his parents, and [[AnimatedMusical they all sing songs]] by the composer of ''Theatre/ByeByeBirdie''.
* ''WesternAnimation/AllHailKingJulien'': [[WesternAnimation/MilesFromTomorrowland Admiral Watson]] is made king of the lemurs by his uncle [[Series/HappyDays the Fonz]]. He rules with the help of [[WesternAnimation/LoonaticsUnleashed Tech E. Coyote]], [[Film/RunFatboyRun Maya]], and [[WesternAnimation/JusticeLeagueAction Chronos]]. His subjects include WesternAnimation/JohnnyBravo, [[WesternAnimation/ThePowerpuffGirls Ace]], [[Film/LooneyTunesBackInAction Foghorn Leghorn]], [[WesternAnimation/StarVsTheForcesOfEvil Coblat]], [[Anime/TheCatReturns Natoru]], and [[WesternAnimation/BuzzLightyearOfStarCommand Warp Darkmatter]]. [[WesternAnimation/{{Chowder}} Mung Daal]] is a recurring villain.
* ''WesternAnimation/AlmostNakedAnimals'': [[WesternAnimation/{{Cyberchase}} Delete]] manages a hotel with his best friend [[WesternAnimation/JacobTwoTwo Leo Louse]]. Other staff members include [[Anime/{{Bakugan}} Alice Gehabich]], [[WesternAnimation/RocketMonkeys YAY-OK]], [[WesternAnimation/JimmyTwoShoes Lucius Heinous VII]], [[WesternAnimation/SevenLittleMonsters Four]], and [[WesternAnimation/ScaredySquirrel Sally Fishlips]]. Their business rival is [[WesternAnimation/{{Grojband}} Trina Riffin]] and her sidekick [[Series/{{Wilbur}} Wilbur the Calf]]. Also, [[WesternAnimation/TotalDrama Chris McLean]] is a stuntman that Delete idolizes.
* ''Comicbook/TheAmazingScrewOnHead'': [[Film/ShootEmUp An unkempt assassin]] and his BattleButler [[WesternAnimation/{{Ratatouille}} Remy]] must save the world from his ex-BattleButler zombie [[Film/Hellboy2004 Abe Sapien]].
* ''WesternAnimation/TheAmazingWorldOfGumball'': [[WesternAnimation/YoungJustice2010 Beast Boy]] (WesternAnimation/{{Chowder}} in the pilot; [[Series/TheGoldbergs Chad Kremp]] in Seasons 3-5; [[WesternAnimation/LEGOStarWarsTheFreemakerAdventures Rowan Freemaker]] in Seasons 5-6) gets into various highjinks with his family and friends, usually with his goldfish-turned-brother [[WesternAnimation/TheLooneyTunesShow Gossamer]] ([[Theatre/{{Matilda}} Nigel]] in the pilot; [[Series/TheWhispers Ethan]] in Seasons 3-5; [[Series/{{Containment}} Thomas]] in Seasons 5-6; [[WesternAnimation/{{TOTS}} Freddy]] in Season 6), his sister [[WesternAnimation/AdventureTime Me-Mow]] or his parents [[WesternAnimation/RainbowRangers Preston Praxton]] and [[VideoGame/XenobladeChronicles2 Queen Raqura]]. [[WesternAnimation/ThomasAndFriends Diesel]] works in every job. [[Film/ThePhantomMenace Sebulba]] was several supporting characters in the first season. Also, Santa Claus leads a double life as an AxCrazy [[WesternAnimation/{{Tarzan}} hunter]] named [[WesternAnimation/PeppaPig Grampy Rabbit]].
* ''WesternAnimation/AmericanDad'': [[WesternAnimation/TheClevelandShow Tim the Bear]] is a government agent working for [[Series/StarTrekTheNextGeneration Captain Picard]]. He is married to [[Film/{{Innerspace}} Wendy]] and has two kids named [[Series/{{ER}} Dr. Archie Morris]] and [[WesternAnimation/CodenameKidsNextDoor Numbuh 362]], an alien named [[WesternAnimation/FamilyGuy Brian Griffin]], and a German fish named [[WesternAnimation/SpongeBobSquarePants Bubble Bass]]. Two of Morris's friends are [[Film/RevengeOfTheNerds Booger]] and [[Film/AmericanPie Finch]].
* ''WesternAnimation/AmericanDragonJakeLong'': [[WesternAnimation/AvatarTheLastAirbender Prince Zuko]] is an Asian-American teenager who can transform himself into a dragon. His grandfather, [[WesternAnimation/HiHiPuffyAmiYumi Kaz]], is his mentor and [[WesternAnimation/AdventureTime Jake the Dog]] joins him. His parents are [[WesternAnimation/{{Futurama}} Amy Wong]] and WesternAnimation/JohnnyBravo and his sister is [[Series/PhilOfTheFuture Pim Diffy]]. He later has a complicated relationship with [[WesternAnimation/TheOwlHouse Amity Blight]].
* ''WesternAnimation/{{Amphibia}}'': [[Series/TheSuiteLifeOfZackAndCody London Tipton]] is magically transported to a world inhabited by frogs, where she befriends [[WesternAnimation/MilesFromTomorrowland the second Miles Callisto]], who lives in the town of Wartwood with his grandfather WesternAnimation/{{Goofy}} and little sister [[WesternAnimation/ThePowerpuffGirls2016 Blossom]]. However, London's friends, [[WesternAnimation/BigCityGreens Gloria]] and [[WesternAnimation/ArloTheAlligatorBoy Alia]], have also been transported to the same world and have teamed up with [[Anime/SoulEater Excalibur]] and [[WesternAnimation/ThePrincessAndTheFrog Dr. Facilier]] respectively. The denizens of Wartwood include the mayor [[WesternAnimation/KingOfTheHill Bill Dauterive]] and his sidekick WesternAnimation/{{Wander|OverYonder}}, spooky kid [[Series/OneMississippi Jessie]] and her triplet sisters [[Series/SingleParents Sophie Cooper]] and [[Series/TheReallyLoudHouse Lana and Lola Loud]], resident nutjob [[Franchise/KingdomHearts Xigbar]], and Miles' crush [[WesternAnimation/{{Storks}} Tulip]], who is the daughter of [[Anime/{{Aggretsuko}} Retsuko's mother]] and the granddaughter of [[Anime/DigimonTamers Terriermon]].
* ''WesternAnimation/AngelaAnaconda'': The creator of ''WesternAnimation/PepperAnn'' is rivals with AlphaBitch [[WesternAnimation/{{Franklin}} Badger]], who is the TeachersPet of [[WesternAnimation/BlazingDragons Sir Blaze]]. Her friends are WesternAnimation/ElliotMoose, [[WesternAnimation/TotalDrama Samey]], and [[Anime/{{Dangaioh}} Roll Kran]].
* ''WesternAnimation/TheAngryBeavers'': [[WebAnimation/HelluvaBoss Crimson]] and [[WesternAnimation/OKKOLetsBeHeroes a warlock]] are brothers who have many misadventures in their Northern Oregon home. [[VideoGame/BatmanArkhamAsylum The Riddler]] and [[VideoGame/StarWarsTheOldRepublic Karrels Javis]] are friends of theirs and [[Series/{{Friends}} Jasmine]] is the warlock's girlfriend.
* ''WesternAnimation/{{Animaniacs}}'': [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Carl Wheezer]], [[WesternAnimation/TwoStupidDogs Secret Squirrel]], and [[WesternAnimation/AdventuresOfTheGummiBears Lady Bane]] are a trio of cartoon siblings who run amuck pestering people. [[WesternAnimation/TheCritic Jeremy Hawke]] is a gangster pigeon, [[Theatre/AnnieGetYourGun Annie Oakley]] and [[Franchise/ScoobyDoo Fred Jones]] are a homeless cat and dog, [[WesternAnimation/TheSimpsons Bart Simpson]] is a happy-go-lucky toddler who causes her dog [[WesternAnimation/TinyToonAdventures Gogo Dodo]] a lot of grief, [[WesternAnimation/MyGymPartnersAMonkey Principal Pixiefrog]] and [[WesternAnimation/DannyPhantom Jack Fenton]] are [[WesternAnimation/PinkyAndTheBrain two lab rats who constantly plot to]] TakeOverTheWorld, and [[Series/LittleHouseOnThePrairie Rachel Brown Oleson]] and [[WesternAnimation/{{Histeria}} Froggo]] are cartoon squirrels.
** ''WesternAnimation/Animaniacs2020'': Carl, Secret, and Bane are back for more cartoon antics.
** [[WesternAnimation/TheTransformers Megatron]] doesn't like the trio turning up behind him all of a sudden and tells them not to do that. However, Carl tells them not to ask them, but to ask [[WesternAnimation/DaveTheBarbarian Chuckles the Silly Piggy]] instead.
* ''WesternAnimation/AnneOfGreenGablesTheAnimatedSeries'': [[WesternAnimation/ToadPatrol Oyster]] lives in Avonlea, Canada with her adopted parents [[WesternAnimation/TheAdventuresOfTintin1991 Professor Cuthbert Calculus]] and [[WesternAnimation/MissSpidersSunnyPatchFriends Betty Beetle]]. Her friends are [[WesternAnimation/{{Sixteen}} Starr]], [[Series/RadioFreeRoscoe Ray Brennan]], [[WesternAnimation/{{Franklin}} Rabbit]], and [[Series/WindAtMyBack Maisey McGinty]]; and their teacher is [[WesternAnimation/CareBears1980s Love-a-Lot Bear]]
* ''WesternAnimation/AquaTeenHungerForce'': [[WesternAnimation/OKKOLetsBeHeroes Doctor Grayman]], [[WesternAnimation/TheBrakShow Thundercleese]], and [[CreatorCameo the shows creator]] all share a house in New Jersey. The narrator of ''WesternAnimation/{{Squidbillies}}'' is their neighbor and [[WesternAnimation/SpaceGhostCoastToCoast Zorak]] is a mad scientist.
* ''WesternAnimation/{{Arcane}}'': [[VideoGame/{{Titanfall}} Kuben Blisk]] takes in two orphaned sisters, [[WesternAnimation/SpiderManSpiderVerse Gwen Stacy]], and a little girl who grows up to be [[Film/MissPeregrinesHomeForPeculiarChildren Emma Bloom]]. Gwen and Emma are raised alongside [[Franchise/Ben10 Ben Tennyson]] and Franchise/SonicTheHedgehog. After a disastrous chain of events that lead to [[spoiler:Emma accidentally killing Ben and Sonic as well as Blisk dying]], the two sisters have a falling out. [[VideoGame/FalloutNewVegas Vulpes Inculta]], Blisk's [[CainAndAbel "brother"-turned-enemy]], takes in Emma as his adoptive daughter while Gwen gets abducted and imprisoned. [[{{Timeskip}} Years later]], Gwen is released by [[Film/HarryPotter Cho Chang]] and comes back home with her to find Emma, who unbeknownst to either of them, has become Vulpes' minion and is far from the sister she once knew.
* ''WesternAnimation/{{Archer}}'': [[WesternAnimation/HomeMovies Coach McGuirk]] is a secret agent working alongside [[WesternAnimation/DextersLaboratory Dee Dee]] for an organization run by his mother, [[Series/{{Dinosaurs}} Fran Sinclair]]. His coworkers include [[WesternAnimation/BoJackHorseman Sextina Aquafina]] (who is also his on again, off again girlfriend), [[WesternAnimation/RickAndMorty Jerry Smith]], [[WesternAnimation/AskTheStorybots Beep]], [[WesternAnimation/FriskyDingo Valerie, Xtacle]], and [[WesternAnimation/SeaLab2021 Dr. Virjay]].
* ''WesternAnimation/AroundTheWorldInEightyDays'': [[WesternAnimation/TheBatman Alfred Pennyworth]] wants to marry [[WesternAnimation/TheJetsons Judy Jetson]], the niece to an unscrupulous aristocrat named [[Theatre/TheMerchantOfVenice Shylock]] who wagers that if Alfred can go [[TitleDrop around the world in eighty days]], he can marry Judy.
* ''WesternAnimation/{{Arthur}}'': [[Series/RadioActive Ethan St. John]] ([[WesternAnimation/TheSaveUms Noodle]] in Seasons 6-11; [[WesternAnimation/BabarAndTheAdventuresOfBadou Badou]] in Seasons 12-19) lives in Elwood City with his parents [[WesternAnimation/Patrol03 Shorty and Carmen]], his younger sister [[ComicStrip/LittleLulu Annie Inch]] ([[WesternAnimation/MonaTheVampire George]] in Seasons 4-6; [[WesternAnimation/PopPixie Fixit]] in Seasons 11-15, WesternAnimation/MikeTheKnight in Seasons 16-17; [[WesternAnimation/PawPatrol Alex]] in Seasons 20-21; [[WesternAnimation/TopWing Rod]] in Seasons 22-25) [[note]]Jason Swzimmer and Andrew Dayton, DW's voice actors in Seasons 7-10 and Seasons 18-19 respectively, have no other known credits[[/note]], and pet dog [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Goddard]]. He attends Lakewood Elementary with his friends, who include [[WesternAnimation/WhatsWithAndy Danny Pickett]], [[Series/AreYouAfraidOfTheDark Kiki]], [[WesternAnimation/CampLakebottom Gretchen]], and [[VideoGame/DeusExHumanRevolution William Taggart]]. Their teacher is [[VideoGame/SplinterCell President David Bowers]] and the principal is WesternAnimation/{{Papa Beaver|sStorytime}}.
* ''WesternAnimation/AsToldByGinger'': [[VideoGame/Spyro2RiptosRage Elora the Faun]] is an ordinary junior high school student who, with her friends [[Anime/CannonBusters Philly the Kid]], [[WesternAnimation/TheWildThornberrys Pippo]], and [[WesternAnimation/ConstantPayne Amanda Payne]], tries to become popular amongst the school's students. [[WesternAnimation/SpiderManTheAnimatedSeries Deborah Whitman]], the resident popular girl, takes a liking to Elora and tries to include her in whatever plans she has, but Deborah's accomplice [[WesternAnimation/{{Rugrats}} Susie Carmichael]] does not like Elora. Meanwhile, Elora's little brother [[WesternAnimation/TheSuperMarioBrosSuperShow Princess Toadstool]] and his best friend [[WesternAnimation/{{Animaniacs}} Dot Warner]] get into their own shenanigans and Elora's mother [[WesternAnimation/TurboFAST Queen Invicta]] often gives her advice. Deborah's younger brother is [[WesternAnimation/DextersLaboratory Agent Honeydew]].
* ''WesternAnimation/AtomicBetty'': [[WesternAnimation/TheBerenstainBears Sister Bear]] lives a secret double life defending the galaxy under the command of [[WesternAnimation/RubyGloom Poe]]. She and her crew, [[WesternAnimation/AtomicPuppet Professor Tite-Gripp]] and [[Series/PuppetsWhoKill Rocko the Dog]], fight Supreme Evil Overlord [[WesternAnimation/TheLegendOfZelda1989 King Harkinian]] and his sidekick [[WesternAnimation/TheRaccoons Bert Raccoon]] (later [[WesternAnimation/SevenLittleMonsters Three]]). Her parents are [[WesternAnimation/{{Cyberchase}} Motherboard]] and [[WesternAnimation/ScaredySquirrel Nestor]]; her friends are [[WesternAnimation/TimothyGoesToSchool Fritz]] and [[WesternAnimation/{{Franklin}} Beaver]]; and [[WesternAnimation/XMenTheAnimatedSeries Jean Grey]] is the AlphaBitch, whose brother [[WesternAnimation/CampLakebottom McGee]] is Sister Bear's love interest.
* ''WesternAnimation/AtomicPuppet'': [[WesternAnimation/ElTigre White Pantera]] is transformed into a sock puppet by his disgruntled sidekick [[WesternAnimation/TotalDrama Cody]] and teams up with [[WesternAnimation/LooneyTunesCartoons Daffy Duck]], who can put him on his hand to become a superhero. The duo fight villains such as [[WesternAnimation/AtomicBetty Sparky]], [[WesternAnimation/NumbChucks Hooves]], and [[WesternAnimation/RubyGloom Skull Boy]]. Daffy's best friend is [[WesternAnimation/TheMysteriesOfAlfredHedgehog Cynthia]] and his family is made of [[WesternAnimation/HeroElementary Mr. Sparks]], [[WesternAnimation/MissSpidersSunnyPatchFriends Spindella]], and [[Anime/{{Bakugan}} Julie Makimoto]]. [[Anime/SailorMoon Kenji Tsukino]] is the local newsman.
* ''WesternAnimation/AvatarTheLastAirbender'': After being frozen for 100 years, [[WesternAnimation/TheBackyardigans Pablo]] (as well as his pets [[VideoGame/GearsOfWar General RAAM]] and [[WesternAnimation/SpongeBobSquarePants Cannonball Jenkins]]) is woken by a young waterbender named [[WesternAnimation/AmericanDragonJakeLong Rose]] and her brother [[Series/OneHundredThingsToDoBeforeHighSchool Jack Roberts]]. Together, along with [[WesternAnimation/MeetTheRobinsons Young Franny]], they journey around the world while being pursued by [[Film/{{Hook}} Rufio]] and his uncle [[WesternAnimation/SamuraiJack Aku]]. After taking care of other villains such as Rufio's rival [[VideoGame/TheWorldEndsWithYou Daisukenojo "Beat" Bito]], [[Franchise/HarryPotter Lucius Malfoy]] and EvilChancellor [[WesternAnimation/YoungJustice2010 King Faraday]], everyone must defeat Rufio's manipulative sister [[Franchise/ScoobyDoo Daphne Blake]] and their EvilOverlord father [[Franchise/StarWars Luke Skywalker]].
** ''WesternAnimation/TheLegendOfKorra'': [[Series/{{Entourage}} Amy Miller]], the reincarnation of Pablo, is taught airbending by [[Film/SpiderManTrilogy J. Jonah Jameson]], the son of Pablo and Rose. [[Series/MarriedWithChildren Bud Bundy]] and [[Film/HorribleBosses Kenny Sommerfeld]] are two brothers who are her friends; [[Film/TheLastAirbender Princess Yue]] is the {{TheTeam|Normal}} BadassNormal, while [[WesternAnimation/TransformersPrime Starscream]] and [[WesternAnimation/TransformersAnimated Lockdown]] are working to rid the world of bending. Meanwhile, an old threat of [[spoiler:bloodbender]] [[Franchise/DCAnimatedUniverse Lex Luthor]] returns in the form of [[WesternAnimation/StarWarsTheCloneWars Captain Rex]]. [[Series/{{Lost}} Jin-Soo Kwon]], [[Series/MadMen Sally Draper]], and [[Film/AustinPowers Frau Farbissima]] are also involved. Pablo, Jack, Rose, and Franny's future selves are [[WesternAnimation/{{Dinosaur}} Aladar]], [[WesternAnimation/BackAtTheBarnyard Otis]], [[Film/NorthByNorthwest Eve Kendall]] and [[Manga/{{Naruto}} Sakura Haruno]] respectively.
** In the second season, Amy must stop her uncle, [[Series/SonsOfAnarchy Officer Craft]], from releasing the ancient spirit of chaos [[WesternAnimation/GreenLanternTheAnimatedSeries Atrocitus]] from his prison. Meanwhile, [[WesternAnimation/HarveyBirdmanAttorneyAtLaw Mentok the Mindtaker]] attempts to profit off a civil war, and it's revealed that 10,000 years ago, the Avatar was created when [[Series/TheWalkingDead Glen]] fused with [[VideoGame/ValkyriaChronicles Selvaria Bles]] to defeat Atrocitus.
** In the third season, a spiritual event gives random nonbenders--among them Jonah's brother [[Film/OfficeSpace Tom Smykowski]] and Franny's granddaughter (via Farbissima's half-sister [[WesternAnimation/AdventureTime Cherry Cream Soda Gal]]) [[VideoGame/KingdomHearts358DaysOver2 Xion]]--airbending. Unfortunately, one of the ''other'' parties affected is the BadassNormal [[BombThrowingAnarchists anarchist]] [[WesternAnimation/AdventureTime Bob Rainicorn]]...and he proceeds to break out of jail, spring his ColdSniper girlfriend [[WesternAnimation/TransformersRobotsInDisguise Windblade]] and their friends MagmaMan [[VideoGame/DawnOfWar Azariah Kyras]] and DisabledBadass BloodKnight [[WesternAnimation/TUFFPuppy Kitty Katswell]] from their tailored cells, and go gunning for Amy. [[spoiler:And their sleeper agent [[WesternAnimation/{{Futurama}} Kif Kroker]] was already in Cherry's city...]]
** In the final season, Amy is recuperating from the events of the previous with the help of Rose/Eve [[spoiler:and later Franny/Sakura, who's become [[Anime/DigimonAdventure Mimi Tachikawa]] in her old age]]. Meanwhile, [[WesternAnimation/TeenageMutantNinjaTurtles2012 Mona Lisa]]--aided by Kenny, Mentok, [[Manga/KOn Yui Hirasawa]] and [[Manga/SgtFrog Keroro]]--starts a war; and Jin resurfaces to apologize to Yue for having wronged her [[spoiler:before getting killed by Mona Lisa's giant mecha]]. When all is said and done, [[WesternAnimation/BlazeAndTheMonsterMachines Stripes]] [[spoiler:has abdicated the throne of the Earth Kingdom to pursue a career as a singer]], and [[spoiler:Amy hooks up with Yue]] at Mentok and Yui's wedding reception.
* ''WesternAnimation/AvengersAssemble'': Patriotic SuperSoldier [[VideoGame/ResidentEvil5 Chris Redfield]], the armor-clad [[Series/{{Heroes}} Nathan Petrelli]][[TheOtherDarrin /]][[WesternAnimation/KungFuPandaLegendsOfAwesomeness Po]] (whose armor is supported by the A.I. [[WesternAnimation/TransformersPrime Hardshell]]), God of Thunder [[Manga/FullmetalAlchemist Roy Mustang]], the savage [[VideoGame/BatmanArkhamCity Solomon Grundy]], archer [[VideoGame/DeadOrAlive Ryu Hayabusa]], spy [[Anime/BlueGender Marlene Angel]], and the winged [[WesternAnimation/Ben10Omniverse Rook Blonko]] are a team of superheroes. Among the villains are Chris' archenemy [[VideoGame/TransformersWarForCybertron Air Raid]], the cybernetically-enhanced [[WesternAnimation/LoonaticsUnleashed Optimatus]], Asgardian troll [[WesternAnimation/YoungJustice2010 Martian Manhunter]], ruler of Latveria [[WesternAnimation/CodenameKidsNextDoor Father]], the vampire [[WesternAnimation/TheSecretSaturdays V.V. Argost]], and corrupt businessman [[WesternAnimation/GreenLanternTheAnimatedSeries Razer]].
** Season 2: It's revealed that Air Raid is working with [[VideoGame/StreetFighterIV Sagat]]. Among other villains are the robotic [[ComicBook/DCTheNewFrontier Slam Bradley]] and a super villain group consisting of [[VideoGame/BatmanArkhamOrigins Black Mask]], [[WesternAnimation/BewareTheBatman Batman]], [[VideoGame/DeadOrAlive Christie]], [[WesternAnimation/YoungJustice2010 Kid Flash]], [[WesternAnimation/OzzyAndDrix Osmosis Jones]], and WesternAnimation/SamuraiJack. In the season finale, Sagat returns with a [[TheVoiceless silent brute]], [[Anime/LuckyStar Yukata Kobayakawa, Kagami Hiiragi]], [[WesternAnimation/XMenEvolution Professor Charles Xavier]], and [[WesternAnimation/SuperFriends Desaad]] working for him.
* ''WesternAnimation/TheAvengersEarthsMightiestHeroes'': [[Anime/CrayonShinChan Hiro Nohara]], [[VideoGame/DragonAgeOrigins the Arishok]], [[Franchise/MassEffect Saren Arterius]] (the personification of [[Series/{{Revenge}} Nolan Ross]]'s anger), [[VideoGame/BatmanArkhamSeries the Riddler]], and [[Anime/DigimonAdventure Sora Takenouchi]] form a team of superheroes. They're soon joined by [[WesternAnimation/GIJoeRenegades Zartan]], [[VideoGame/MetalGearSolid Sigint]], and [[WesternAnimation/JusticeLeagueUnlimited Captain Atom]] in Season 1 and [[VideoGame/KnightsOfTheOldRepublic Bastila]] and [[Franchise/MassEffect Sovereign]] in Season 2. Among their enemies are [[VideoGame/Uncharted2AmongThieves Zoran Lazarevic]], [[VideoGame/NoMoreHeroes Travis Touchdown]], [[Literature/{{Durarara}} Celty Sturluson]], [[WesternAnimation/Ben10 Diamondhead]], [[WesternAnimation/TransformersPrime Ratchet]], [[WesternAnimation/JusticeLeagueCrisisOnTwoEarths Martian Manhunter]], [[WesternAnimation/TheGarfieldShow Jon Arbuckle]], [[Franchise/AlienVsPredator Carl Bishop Weyland]], and [[VideoGame/MetalGearSolid2SonsOfLiberty Vamp]]. [[Series/{{Becker}} Jake Malinack]] and [[Series/{{Sliders}} Maggie Beckett]] are part of a government agency that sometimes works with the team.
** Season 2 welcomes the Fantastic Four, composed of [[WesternAnimation/StarWarsTheCloneWars Captain Rex]], [[VideoGame/BatmanArkhamAsylum Bane]], [[WesternAnimation/SupermanTheAnimatedSeries Jimmy Olsen]], and [[VideoGame/GodOfWar Athena]], as well as more heroes, including [[WesternAnimation/JusticeLeagueDoom Cyborg]], [[Series/TheJamieFoxxShow Braxton P. Hartnabrig]], [[WesternAnimation/BatmanTheAnimatedSeries Dick Grayson]], [[Anime/WolfsRain Tsume]], [[VideoGame/SonicTheHedgehog2006 Princess Elise]], [[Anime/TengenToppaGurrenLagann Leeron Littner]], [[Series/{{Fringe}} Phillip Broyles]], [[Series/DrakeAndJosh Drake Parker]] ([[TheOtherMarty who was once]] [[WesternAnimation/GreenLanternTheAnimatedSeries the Green Lantern]]), [[VideoGame/FinalFantasyXIII Yaag Rosch]], and [[Anime/CowboyBebop Spike Spiegel]]. Among the new villains are [[WesternAnimation/TheBatman Metallo]], [[WesternAnimation/{{Rugrats}} Tommy Pickles]], [[WesternAnimation/{{CatDog}} Eddie the Squirrel]], [[VideoGame/BatmanArkhamCity Clayface]], [[WesternAnimation/MortalKombatDefendersOfTheRealm Shang Tsung]], [[VideoGame/StarCraftII Zeratul]], [[VideoGame/StreetFighterIV Ryu]], [[Series/StarTrekTheNextGeneration Data]], [[WesternAnimation/BeastWars Megatron]], [[WesternAnimation/GeneratorRex Van Kleiss]] (who is pursued by a team of heroes consisting of [[Franchise/{{Halo}} Master Chief]], [[WesternAnimation/TeenTitans2003 Malchior]], [[VideoGame/BatmanArkhamCity Two-Face]], [[Literature/BludgeoningAngelDokuroChan Zansu]], and [[WesternAnimation/MyLifeAsATeenageRobot Brit Crust]]), [[Film/TransformersDarkOfTheMoon Laserbeak]], and [[Film/Underworld2003 Raze]].
* ''WesternAnimation/TheAvengersUnitedTheyStand'': [[WesternAnimation/RescueHeroes Jack Hammer]], Anime/SailorMoon, [[Anime/BakutenShootBeyblade Boris Balkov]], [[WesternAnimation/XMenTheAnimatedSeries Morph]], [[Series/KungFu1972 Lulu Morgan]], [[WesternAnimation/InspectorGadget2015 Dr. Claw]], [[Anime/OutlawStar Aisha Clanclan]], and [[Series/RadioFreeRoscoe Principal Waller]] are a team of superheroes.
!!B
* ''Literature/{{Babar}}'': [[Series/TheRedGreenShow Hap Shaughnessy]] rules a kingdom of elephants with his wife [[WesternAnimation/CadillacsAndDinosaurs Governor Scharnhorst]], his brother-in-law [[WesternAnimation/FlyingRhinoJuniorHigh Buford]], and his children [[Series/ThePolitician Ricardo]], [[Series/ReadyOrNot1993 Mona]], [[WesternAnimation/TheMagicSchoolBus Ralphie Tennelli]], and [[WesternAnimation/TimothyGoesToSchool Yoko]]. He was tutored by [[WesternAnimation/{{Beetlejuice}} Delia Deetz]] and [[Film/SawV Bernie]] is his closest friend. His advisors are [[Series/FridayThe13thTheSeries Jack Marshak]] and [[WesternAnimation/MaggieAndTheFerociousBeast The Ferocious Beast]], while [[WesternAnimation/TheRaccoons George Raccoon]] is his chef. [[WesternAnimation/{{Rupert}} Constable Growler]] and [[WesternAnimation/BeverlyHillsTeens Nikki Darling]] rule a rival kingdom of rhinos with their son [[Series/KungFuTheLegendContinues Chuckie]] and their advisor [[WesternAnimation/BlazingDragons Sir Burnevere]]. Governor Scharnhorst was [[WesternAnimation/TeenTitans2003 Raven]] as a child.
** (2000 revival): Hap Shaughnessy and Governor Scharnhorst are now [[WesternAnimation/{{Mysticons}} Nova Terron]] and [[WesternAnimation/JacobTwoTwo Florence]], while their first three kids are now [[WesternAnimation/{{Franklin}} Franklin, Snail, and Rabbit]]. They now travel the world via hot-air balloon and have magical adventures in different lands alongside Bernie (who is now [[WesternAnimation/{{Cyberchase}} the second Buzz]]).
** ''WesternAnimation/BabarAndTheAdventuresOfBadou'': The adventures of Hap's grandson [[WesternAnimation/{{Arthur}} Arthur Read]] (son of Ricardo, who is now [[WesternAnimation/LittleBear Rusty Bear]]), whose circle of friends includes Bernie's daughter [[WesternAnimation/DNAce Sloane Plunderman]], as well as WesternAnimation/{{Max|AndRuby}}, [[WesternAnimation/JaneAndTheDragon Princess Lavinia]], and [[WesternAnimation/{{Stoked}} George Ridgemount]]. Their teacher is [[WesternAnimation/RoliePolieOlie Polina Polie]]. Also, [[WesternAnimation/DonkeyKongCountry King K. Rool]] is the scheming ambassador of a kingdom of crocodiles whose nephews are [[WesternAnimation/{{Grojband}} Corey Riffin and Kin Kujira]], while [[WesternAnimation/TotalDrama Trent]] rules the savannah. Constable Growler and Nikki Darling are now [[WesternAnimation/AtomicBetty Admiral DeGill]] and [[WesternAnimation/{{Wayside}} Miss Mush]], and their grandson [[Anime/{{Medabots}} Ikki Tenryou]] is Arthur's rival.
* ''WesternAnimation/BabyLooneyTunes'': [[WesternAnimation/EdEddNEddy Double D]], [[Manga/CardcaptorSakura Julian]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Party Favor, Igneous Rock]], [[WesternAnimation/SittingDucks Bill]], [[WesternAnimation/StrawberryShortcake Blueberry Muffin]], Anime/{{Hamtaro}}, and [[Manga/{{Inuyasha}} Kagura]] are baby versions of the ''WesternAnimation/LooneyTunes'', cared for by [[WesternAnimation/SpiderManAndHisAmazingFriends Aunt May]] and her nephew [[Anime/DragonBallZ Vegeta]].
* ''WesternAnimation/BackAtTheBarnyard'': [[WesternAnimation/SanjayAndCraig Craig]], [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Sheen Estevez]], [[VideoGame/MetalGearSolid Liquid Snake]], [[WesternAnimation/BubbleGuppies Mr. Grouper]], [[WesternAnimation/DannyPhantom the Box Ghost]], [[Series/GoodLuckCharlie Amy Duncan]], [[Series/TheNewAdventuresOfOldChristine Barb Baran]], and [[WesternAnimation/HeyArnold Ernie Potts]] are a group of farm animals who go on adventures when their master, [[VideoGame/TransformersWarForCybertron Ratchet]] isn't looking. [[Film/KungPowEnterTheFist The Chosen One]] and [[WesternAnimation/WordGirl Mrs. Botsford]] are their neighbors.
* ''WesternAnimation/BackToTheFuture'': [[WesternAnimation/DannyPhantom Danny Fenton]] goes on adventures in time with [[WesternAnimation/TheSimpsons Homer Simpson]], Homer's wife [[Film/{{Elf}} Emily Hobbs]] and Homer's sons [[WesternAnimation/TheSpectacularSpiderMan Peter Parker]] and [[Series/LeaveItToBeaver Kevin Cleaver]]; Danny's girlfriend [[WesternAnimation/ThePowerpuffGirls Blossom]] sometimes travels with them too. [[WesternAnimation/BatmanTheAnimatedSeries Tony Zucco]] and his various ancestors often cause trouble for Danny and Homer. In live action segments at the end of the show, Homer, now [[Film/StarTrekIIITheSearchForSpock Commander Kruge]], is assisted by Series/BillNyeTheScienceGuy.
* ''WesternAnimation/BadDog'': The misadventures of an obsessively obedient dog owned by WesternAnimation/GeorgeShrinks, whose older siblings are [[WesternAnimation/TotalDrama Courtney]] and [[VideoGame/MegaManLegends Teisel Bonne]], parents are [[WesternAnimation/TheAdventuresOfSamAndMaxFreelancePolice Sam]] and [[Series/LittleMosqueOnThePrairie Sarah Hamoudi]], and grandfather is [[WesternAnimation/{{Babar}} Basil]].
* ''WesternAnimation/TheBagelAndBeckyShow'': [[WesternAnimation/InvaderZIM Almighty Tallest Purple]] and [[WesternAnimation/{{Mysticons}} Oozie Q]] are siblings who have adventures in the town of Awkward Hills with their friend, [[WesternAnimation/ThreeAmigonauts Burt]]. [[WesternAnimation/RoliePolieOlie Bonita Bevel]] is their mother.
* ''WesternAnimation/TheBatman'': [[Anime/SailorMoon Tuxedo Mask]] is a masked vigilante who, with the help of his sidekicks [[Manga/{{Naruto}} Tenten]] and [[Film/RaisingHelen Oliver Portman]], fights villains such as [[WesternAnimation/DannyPhantom Skulker]], [[WesternAnimation/RockosModernLife Heffer Wolfe]], [[VideoGame/GodOfWar Hades]], [[Anime/AfroSamurai Justice]], [[Franchise/ANightmareOnElmStreet Freddy Krueger]], [[WesternAnimation/TeenTitans2003 Blackfire]], [[Film/GhostbustersII Janos Poha]], [[WesternAnimation/AGoofyMovie Max Goof]], [[WesternAnimation/TheSimpsons Homer Simpson]], and [[Film/MortalKombatAnnihilation Lord Raiden]]. [[VideoGame/LegacyOfKain Mortanius]] is Tuxedo Mask's butler and Tenten's police commissioner father is [[Series/TheXFiles Agent Skinner]]. Other cops include [[Series/BattlestarGalactica2003 William Adama]] / [[WesternAnimation/{{Gargoyles}} Jade]], [[Series/ThePractice Eugene Young]], and WesternAnimation/{{Mulan}}.
* ''WesternAnimation/BatmanTheBraveAndTheBold'': [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Hoss Delgado]], along with other superheroes like [[WesternAnimation/TheSpectacularSpiderMan Harry Osborn]], [[WesternAnimation/ThunderCats2011 Lion-O]], [[WesternAnimation/TheFairlyOddParents Cupid]], [[Film/FullMetalJacket Gunnery Sergeant Hartman]], and [[VideoGame/FinalFantasyXII Gilgamesh]], fight off villains like [[WesternAnimation/Ben10AlienForce Azmuth]], [[VideoGame/GodOfWar Hermes]], [[WesternAnimation/TeenTitans2003 Control Freak]], and [[WesternAnimation/CodenameKidsNextDoor Numbuh 86]]. In the end, [[Series/HappyDays Arthur 'Fonzie' Fonzarelli]] tries to save the show from getting cancelled.
** One episode has Hoss facing off against the [[TheMusicMeister hypnotic powers]] of [[Series/HowIMetYourMother Barney Stintson]].
** [[Franchise/ScoobyDoo A movie]] involves Hoss teaming up with [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Goddard]], [[Film/Scream1996 Stuart Macher]], [[WesternAnimation/HiHiPuffyAmiYumi Yumi Yoshimura]], [[Series/TheFactsOfLife Natalie]], and [[Franchise/{{Transformers}} Megatron]].
** In the advertisement for the tie-in game, he, along with [[Franchise/RatchetAndClank Ratchet]], take some time off to play video games at the insistence of [[Creator/PaulReubens Pee-wee Herman]].
* ''WesternAnimation/BeastWars'': The heroic Maximals [[WesternAnimation/RollBots Lance]], [[Anime/DragonBallZ Captain Ginyu]], & WesternAnimation/{{Mega Man|RubySpears}}, led by [[WesternAnimation/MegaManRubySpears Guts Man]], battle the evil [[WesternAnimation/TransformersAnimated Optimus Prime]] and his Predacon forces, composed of [[Anime/DragonBallZ Mr. Satan, Oolong]], [[Anime/UnicronTrilogy Tidal Wave]], and [[WesternAnimation/MegaManRubySpears Eddie]], who is the TheChewToy. [[WesternAnimation/XMenEvolution Wolverine]] pulls a HeelFaceTurn and becomes VitriolicBestBuds with Lance. [[Anime/SaberMarionetteJ Tiger]] also switches sides to be with [[Manga/BlackLagoon Verrocchio]]. [[Series/{{Supernatural}} Dr. Jennings]], [[Manga/MaisonIkkoku Yukari Godai]], and [[VideoGame/CallOfDuty Lt. Vasquez]] later join the Maximals, while [[Series/{{Sanctuary}} Helen Magnus' dad]], [[Anime/MegaManNTWarrior Count Zap]], and [[Series/BattlestarGalactica2003 The First Hybrid]] join the Predacons.
** ''WesternAnimation/BeastMachines'': Immediately following the events on Earth, Guts Man, Mega Man, Lance, and Tiger return to their home planet only to discover that Optimus Prime has taken it over with his henchmen, [[Toys/{{Bionicle}} Matau]] ([[spoiler:in actuality, Verrocchio]]), [[VideoGame/DawnOfWar Gabriel Angelos]] ([[spoiler:Ginyu]]) and [[Series/{{Highlander}} Joe Dawson]] ([[spoiler:Eddie]]). Now, with the help of [[WesternAnimation/XMenEvolution Gambit]] and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Queen Chrysalis]], they must bring balance to the planet and stop the Vehicons. [[WesternAnimation/WarPlanets Graveheart]] and [[Manga/BlackLagoon Balalaika]] later join up with Optimus after the "departures" of Matau and Gabriel.
* ''WesternAnimation/BeatBugs'': [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rainbow Dash]], [[WesternAnimation/{{Dinotrux}} Albert]], [[WesternAnimation/LittlestPetShopAWorldOfOurOwn Edie Von Keet]], [[Series/TheGoodDoctor Marcie Murphy]], and [[WesternAnimation/KidVSKat Coop Burtonburger]] are five young bug friends who learn valuable life lessons through covers of songs by Music/TheBeatles. Recurring characters include [[Anime/DragonBallZ Vegeta]], [[WesternAnimation/BarbieInAChristmasCarol the Spirit of Christmas Future]], [[WesternAnimation/EdEddNEddy Rolf, Jonny 2x4]], [[Film/TheSantaClause2 a seismic interpreter]], [[WesternAnimation/{{Ninjago}} Acronix]], [[Manga/BlackLagoon Revy]], [[WesternAnimation/SabrinaTheAnimatedSeries Uncle Quigley]], [[Manga/DeathNote Misa Amane]], and [[WesternAnimation/JohnnyTest Mary Test]].
* ''WesternAnimation/BeavisAndButtHead'': [[WesternAnimation/KingOfTheHill Hank Hill]] and [[WesternAnimation/SouthParkBiggerLongerAndUncut Kenny McCormick]] are two idiotic teens who like to watch music videos and snark on them when they're not making mischief.
* ''WesternAnimation/BeethovenTheAnimatedSeries'': [[Series/MadMen Freddy Rumsen]] is a friendly St. Bernard who drives his owners [[WesternAnimation/SupermanTheAnimatedSeries Sam Lane]] and [[WesternAnimation/DannyPhantom Maddie Fenton]] crazy and goes on adventures with his friends [[Film/BadBoys1995 Captain Howard]], [[WesternAnimation/TinyToonAdventures Babs Bunny]], and [[WesternAnimation/SpongeBobSquarePants Patrick Star]]. The family also includes Sam and Maddie's children [[Series/TheNanny Maggie Sheffield]], [[WesternAnimation/TheSwanPrincess Derek]], and [[WesternAnimation/HeyArnold Helga Pataki]] as well as their pet hamster [[WesternAnimation/AvatarTheLastAirbender Guru Pathik]].
* ''WesternAnimation/{{Beetlejuice}}'': [[VideoGame/ResidentEvil Claire Redfield]] is a PerkyGoth that hangs out with the ghostly [[WesternAnimation/XMenTheAnimatedSeries Angel]]. Claire's parents are [[Series/MurdochMysteries Mr. Todd]] and [[WesternAnimation/LittleBear Hen]], while Angel's neighbors are [[WesternAnimation/CareBears1980s Professor Coldheart]], [[WesternAnimation/{{Babar}} Movie!Rataxes]], and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rarity]]. Angel's vehicle is [[WesternAnimation/StickinAround Mr. Lederhosen]] (who sometimes transforms into [[WesternAnimation/{{Rupert}} The Professor]]), his parents are [[WesternAnimation/TheRaccoons Bert and Melissa Raccoon]], and his goody-two-shoes younger brother is [[WesternAnimation/MissSpidersSunnyPatchFriends Felix the Frog]]. [[WesternAnimation/BatmanTheAnimatedSeries Batgirl]] is the AlphaBitch.
* ''WesternAnimation/BeingIan'': [[WesternAnimation/{{Dinotrux}} Revvit]] is a young boy with aspirations of filmmaking. His family is made up of his parents, [[Anime/PowerpuffGirlsZ Professor Utonium]] and [[Anime/DragonBallZ Android 19]], and his older brothers, [[WesternAnimation/ClassOfTheTitans Herry]] and [[WesternAnimation/EdEddNEddy Ed]]. His best friends are [[WesternAnimation/HotWheelsWorldRace Nolo Passaro]] and [[WesternAnimation/JimmyTwoShoes Heloise]]; his respective paternal and maternal grandmothers are [[WesternAnimation/PollyPocket Griselle Grande]] and [[WesternAnimation/ChipAndPotato Grandma Pug]]; and [[WesternAnimation/AdventuresOfSonicTheHedgehog Coconuts]] is a FunnyForeigner who works at Professor Utonium's piano store. The show was created by [[Manga/DragonBall Goku]].
* ''WesternAnimation/Ben10'': [[WesternAnimation/TheFairlyOddParents Timmy Turner]] finds an alien artifact that can turn him into numerous aliens (such as [[WesternAnimation/AvatarTheLastAirbender Appa]], [[VideoGame/RatchetAndClank Captain Qwark]], [[Anime/TheBigO Roger Smith]], [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Eight-Armed Willy]], [[WesternAnimation/SquirrelBoy Rodney J. Squirrel]], [[WesternAnimation/DannyPhantom Fright Knight]], and [[WesternAnimation/MonstersVsAliens General W.R. Monger]]). With the help of his cousin [[WesternAnimation/AllGrownUp Rachel]] and his grandpa [[VideoGame/MetalGearSolid Colonel Roy Campbell]], he squares off against people like [[WesternAnimation/TheAvengersEarthsMightiestHeroes Red Skull]], [[VideoGame/MetalGearSolid3SnakeEater Ivan Raidenovitch Raikov]] ([[Anime/DigimonFrontier Takuya Kanbara]] in his first appearance), [[WesternAnimation/YoungJustice2010 Aqualad]] and his niece [[Anime/SamuraiChamploo Fuu]], and [[VideoGame/XMenLegends Beast]].
** ''WesternAnimation/Ben10AlienForce'': Timmy has matured into [[Manga/{{Naruto}} Sasuke Uchiha]], Rachel has also matured into [[VideoGame/TheLastOfUs Ellie]], Raikov has had a HeelFaceTurn and matured into [[WesternAnimation/SuperRobotMonkeyTeamHyperforceGo Chiro]], and they've teamed-up against the forces of evil. This time, the bad guys include [[Series/StarTrekTheNextGeneration Wesley Crusher]], [[WesternAnimation/AvatarTheLastAirbender Bato]], and Red Skull (now [[Film/TransformersDarkOfTheMoon Sideswipe]]). Sideswipe has [[WesternAnimation/AmericanDad Klaus]] as a minion. Many of Sasuke's aliens now sound exclusively like Appa, while one sounds like [[WesternAnimation/UltimateSpiderMan2012 the Wrecker]] and another has two personalities, one of whom is [[Film/Godzilla1998 Elsie Chapman]] and the other one is WesternAnimation/{{Batman|TheAnimatedSeries}}.
** ''WesternAnimation/Ben10UltimateAlien'': [[WesternAnimation/CaptainPlanetAndThePlaneteers Ma-Ti]] reveals Sasuke's identity to the public, making him into a celebrity to children and a villain to adults. Sasuke has to overcome this to save the world from [[WesternAnimation/BatmanTheBraveAndTheBold Aquaman]]. Later, Sasuke has to deal with [[WesternAnimation/TeenageMutantNinjaTurtles1987 Splinter]] and [[WesternAnimation/BatmanUnderTheRedHood the Joker]]. The alien with two additional personalities briefly reappear, and this time Elsie is [[WesternAnimation/IceAge Roshan]] while Batman is [[WesternAnimation/{{Gargoyles}} Brooklyn]].
** ''WesternAnimation/Ben10Omniverse'': After Ellie and Chiro leave for college, Sasuke teams up with a rookie alien named [[WesternAnimation/TransformersAnimated Bumblebee]], and they now have to fight [[WesternAnimation/XMenEvolution Professor Charles Xavier]], who turns out to be working for [[VideoGame/BatmanArkhamCity Hugo Strange]] and [[WesternAnimation/TheLooneyTunesShow Marvin the Martian]]. Later on, Sasuke and Bumblebee deal with the return of [[WesternAnimation/TeenageMutantNinjaTurtles2012 Shredder]] and his daughter [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]]. Also, Sideswipe is back to sounding like the Red Skull. Other villains include Klaus's gang (consisting of [[WesternAnimation/TheTransformers Perceptor]], [[WesternAnimation/TheSpectacularSpiderMan Sandman]], and [[WesternAnimation/GIJoeARealAmericanHero the Baroness]]) [[Series/ParksAndRecreation Tom Haverford]], [[Film/TheBreakfastClub John Bender]], [[WesternAnimation/BeastWars Megatron]], [[WesternAnimation/GIJoeResolute Storm Shadow]], and [[Franchise/StarWars Luke Skywalker]]. Many of Sasuke's aliens sound like [[WesternAnimation/AvengersAssemble the Falcon]], [[WesternAnimation/LegionOfSuperHeroes Superman]], [[Manga/InuYasha Sesshomaru]], [[WesternAnimation/SpiderManTheAnimatedSeries Hydro-Man]], and [[WesternAnimation/{{Chowder}} Schnitzel]], with the alien with two personalities now sounding like [[WesternAnimation/StevenUniverse Jasper]] and [[WesternAnimation/TransformersRobotsInDisguise2015 Drift]]. The show is intercut with adventures of Sasuke back when he was Timmy.
* ''WesternAnimation/BenAndHollysLittleKingdom'': Within the miniscule Little Kingdom, there live two types of beings: elves and fairies. [[Film/CrookedHouse Eustace]] the elf is best friends with [[WesternAnimation/PeppaPig Zoë Zebra]] the fairy princess, and regularly go on adventures together. Zoë lives in the Little Castle with her parents, [[Series/{{Pennyworth}} Arthur Pennyworth]] and [[Film/FourWeddingsAndAFuneral Laura]], as well as their housemaker [[WesternAnimation/PeppaPig Miss Rabbit]]. Eustace lives in the Great Elf Tree with his parents WesternAnimation/FiremanSam and [[Series/TheBrittasEmpire Julie Porter]], while [[Series/{{Thunderbirds}} Gordon Tracy]] lives at the top and oversees the elves' duties. [[Series/TheSarahJaneAdventures Mr Smith]] is a caricature of Boris Johnson.
* ''WesternAnimation/BensCity'': [[Anime/SamuraiPizzaCats Speedy Cerviche]] is literally everybody.
* ''Literature/TheBerenstainBears'':
** (1985 series) [[WesternAnimation/TwoStupidDogs Mr. Hollywood]] is married to [[WesternAnimation/LinusTheLionhearted Granny Goodwitch]] and has two kids, [[WesternAnimation/RainbowBrite Krys]] and [[WesternAnimation/APupNamedScoobyDoo Velma Dinkley]]. [[WesternAnimation/CodenameKidsNextDoor Professor XXXL]] is the mayor of the town they live in.
** (2003 series) [[WesternAnimation/DonkeyKongCountry King K. Rool]] is married to [[Series/DueSouth Meg Thatcher]] and has two kids, [[Film/{{Juno}} Paulie Bleeker]] and WesternAnimation/AtomicBetty.
* ''WesternAnimation/BestEd'': [[WesternAnimation/{{Detentionaire}} Principal General Barrage]] and [[WesternAnimation/{{Spliced}} Two-Legs Joe]] are best friends who live in the town of Swellville.
* ''WesternAnimation/BewareTheBatman'': [[Series/ThirdWatch Carlos Nieto]] fights crime with his butler [[Manga/{{Hellsing}} Enrico Maxwell]] and swordswoman [[WesternAnimation/TransformersPrime Arcee]]. [[Series/That70sShow Red Forman]] is a cop who has to learn to trust Carlos. Among the villains they have to deal with are [[WesternAnimation/TheAvengersEarthsMightiestHeroes Falcon]], [[WesternAnimation/DannyPhantom Sam Manson]], [[WesternAnimation/BatmanTheBraveAndTheBold Ocean Master]], and [[WesternAnimation/AvatarTheLastAirbender Guru Pathik]] and his sidekick [[Film/{{Blade}} Dragonetti]]. [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]] is Red's daughter and is a fangirl of Carlos and Arcee.
* ''WesternAnimation/BigCityGreens'': [[CreatorCameo One of the show's creators]] is a country boy who lives in the big city with his sister WesternAnimation/{{Pearlie}}, his dad [[WesternAnimation/TheJungleBook2 Bagheera]], and his grandmother [[Series/ItsAlwaysSunnyInPhiladelphia Artemis Dubois]]. His friends are a nerdy rich kid named [[WesternAnimation/YoungJustice2010 Cyborg]] and a coffee barista named [[WebVideo/RileyRewind Riley Brown]]. His mother, [[Film/{{Bridesmaids}} Rita]], was recently released from prison.
* ''WesternAnimation/BigGuyAndRustyTheBoyRobot'': [[WesternAnimation/KingOfTheHill Bobby Hill]] is the title Boy Robot, who goes on adventures with the Big Guy, who's piloted by [[UsefulNotes/ToysRUs Geoffrey the Giraffe]]. [[Series/BeverlyHills90210 Andrea Zuckerman]], [[WesternAnimation/TeenTitans2003 Val-Yor]], and [[Series/TheDrewCareyShow Mimi]] back them up. Other supporting cast include [[WesternAnimation/KingOfTheHill Bill Dauterive]], [[WesternAnimation/AvatarTheLastAirbender Lion Turtle]], [[Film/TheRockyHorrorPictureShow Dr. Frank N. Furter]] and [[Film/FullMetalJacket Gunnery Sergeant Hartman]]. This show turned out to have an AllStarCast.
* ''WesternAnimation/{{Birdz}}'': [[WesternAnimation/RockAndRule Angel]] is the daughter of [[Anime/SailorMoon Kenji Tsukino]] and [[VideoGame/ResidentEvil Ada Wong]], while her sisters are WesternAnimation/{{Yin|YangYo}} and [[WesternAnimation/XMenTheAnimatedSeries Storm]]. She attends school with [[WesternAnimation/{{Franklin}} Badger]], [[WesternAnimation/BeverlyHillsTeens Tara Belle]], [[WesternAnimation/TotalDrama Justin]], [[WesternAnimation/{{Rupert}} Rupert Bear]], and [[Anime/SamuraiPizzaCats Speedy Cerviche]]; their teacher is [[WesternAnimation/PippiLongstocking Ms. Prysselius]], and the principal is [[WesternAnimation/{{Dinosaucers}} Allo]]. [[WesternAnimation/{{Babar}} Cornelius]] is the local police officer while [[WesternAnimation/TheZhuZhus Mr. Squiggles]] is a patient of Kenji.
* ''WesternAnimation/BlastersUniverse'': [[WesternAnimation/GetEd Mr. Simon Bedlam]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Gilda the Griffon]], and [[WesternAnimation/{{Fangbone}} Venomous Drool]] travel across the galaxy to stop intergalactic villains from destroying their home planet of Omega.
* ''WesternAnimation/BlazeAndTheMonsterMachines'': [[VideoGame/{{Uncharted}} Nathan Drake]] is a super fast monster truck driven by [[WesternAnimation/TheLionGuard Beshte]] (later [[WesternAnimation/TheLoudHouse Clyde]], [[WesternAnimation/TheEpicTalesOfCaptainUnderpants George Beard]], [[WesternAnimation/SpideyAndHisAmazingFriends Miles Morales/Spin]], and [[Series/DramaClub2021 Skip]]). Together, they go on adventures around the city and learn about science. They are accompanied by the mechanic [[WesternAnimation/BubbleGuppies Deema]] (later [[Series/AndiMack Iris]] and [[WesternAnimation/{{Firebuds}} Wiley Riley]]), the tiger truck [[VideoGame/FalloutNewVegas Muggy]], the cowgirl [[Manga/{{Naruto}} Sakura]], the daredevil [[WesternAnimation/TeenTitans2003 Control Freak]], and the dinosaur truck [[WesternAnimation/{{Amphibia}} One-Eyed Wally]]. They run afoul of a cheating monster truck named [[WesternAnimation/YoungJustice2010 Martian Manhunter]], and his perky assistant [[WesternAnimation/{{Disenchantment}} Elfo]], though Manhunter becomes nicer overtime and a friend to Nathan. Later on, Nathan and the others are joined by [[WesternAnimation/{{TOTS}} Ava]].
* ''WesternAnimation/BlazingDragons'': [[WesternAnimation/AngelaAnaconda Gordy Rhinehart]] is a squire for the Knights of the Square Table, comprised of lazy buffoon [[Series/KungFuTheLegendContinues Kermit Griffin]] (later [[WesternAnimation/BlastersUniverse M.E.L.]]), CampGay [[WesternAnimation/{{Redwall}} Basil Stag Hare]], veteran Scot [[WesternAnimation/CareBears1980s Beastly]], large and imposing [[Anime/MetalFightBeyblade Dr. Ziggurat]], and small but gassy [[WesternAnimation/InspectorGadget Chief Quimby]]. Princess [[Anime/SailorMoon Sailor Venus]], the daughter of [[WesternAnimation/DonkeyKongCountry Cranky Kong]] and step-daughter of [[Film/CaesarAndCleopatra2009 Brittanus]], is Gordy's crush. The BigBad is [[Series/FrankieDrakeMysteries Dr. Peter Thomson]] (later [[WesternAnimation/XMenTheAnimatedSeries Professor X]]), whose henchmen are evil knights [[WesternAnimation/TheAdventuresOfTeddyRuxpin Tweeg]] (later [[WesternAnimation/{{Anastasia}} Czar Nicholas II]]), [[Anime/{{Bakugan}} Naga]], and [[WesternAnimation/{{Dinosaucers}} Genghis Rex]], and sorceress [[Series/{{Heartland}} Maggie Duval]]. [[Series/FXTheSeries Captain Marvin Van Duran]] and [[Series/{{Debra}} Principal Ridge]] is the two-headed jester while [[WesternAnimation/{{Birdz}} Mr. Nuthatch]] provides commentary on the characters' adventures.
* ''WesternAnimation/BlessTheHarts'': [[Film/{{Bridesmaids}} Annie Walker]] lives in Greenpoint, North Carolina with her mother [[Film/{{Idiocracy}} Rita]] and her daughter [[Series/{{Workaholics}} Jillian Belk]]. Her boyfriend is [[Film/Neighbors2014 Jimmy Blevins]].
* ''WesternAnimation/BobAndMargaret'': [[WesternAnimation/PeppaPig Dr. Elephant]] (later [[WesternAnimation/AvatarTheLastAirbender Guru Pathik]]) and the show's creator are a married couple living in London. Dr. Elephant/Guru Pathik's Canadian cousins are [[WesternAnimation/MissSpidersSunnyPatchFriends Mr. Mantis]] and [[WesternAnimation/JoJosCircus Ms. Kersplatski]], and his brother [[Film/NightAtTheMuseum Octavius]] is a TV chef. Dr. Elephant/Guru Pathik and the show's creator later move to Toronto where their neighbors are [[WesternAnimation/JacobTwoTwo Principal I.M. Greedyguts]] and [[WesternAnimation/MarvinTheTapDancingHorse Edna]] (later [[WesternAnimation/ScaredySquirrel Nestor's Momma]]).
* ''WesternAnimation/BobbysWorld'': [[WesternAnimation/MuppetBabies1984 Baby Animal]] is a very imaginative little boy. His parents are [[Film/{{Gremlins}} Gizmo]] and [[WesternAnimation/TinyToonAdventures Shirley the Loon]]. His obnoxious siblings are [[WesternAnimation/BaltoIIIWingsOfChange Dusty]] and [[WesternAnimation/JonnyQuestVersusTheCyberInsects Jonny Quest]] (who would later become [[WesternAnimation/KingOfTheHill Bobby Hill]]). Plus there's Aunt [[WesternAnimation/DarkwingDuck Binkie Muddlefoot]] and Uncle [[WesternAnimation/{{Barnyard}} Pig]]. Baby Animal is also best friends with [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Jimmy Neutron]].
* ''WesternAnimation/BobsBurgers'': [[WesternAnimation/{{Archer}} Sterling Archer]] runs a greasy burger shop. Along for the ride is his wife [[Series/LateNight Jimmy's Mom]], awkward teenage daughter [[WesternAnimation/AdventureTime T.V.]], weird son [[Series/{{Delocated}} Evgeni Mirminski]], and sociopath [[WesternAnimation/GravityFalls Mabel Pines]].
* ''WesternAnimation/BobTheBuilder'': (UK; 1999) [[Series/MenBehavingBadly Tony Smart]] is a construction worker who, along with his business partner [[WesternAnimation/TheSecretShow Anita Knight]], complete construction and reparation projects with their team of anthropomorphic construction vehicles, consisting of [[Series/WaterlooRoad Eddie Lawson]], [[WesternAnimation/ThomasAndFriends James]], [[WesternAnimation/ChopSockyChooks Chuckie Chan]], [[WesternAnimation/LavenderCastle Lyca]] and [[Literature/SoulMusic Mort]].
** (UK; 2015) Tony and Anita (now [[Film/HarryPotter Stan Shunpike]] and [[Series/DowntonAbbey Anna Bates]]) move to a new location, and are joined by [[Film/BadBoysForLife Armando]]. Their machines are now WesternAnimation/FiremanSam, [[Series/TheInbetweeners Neil Sutherland]], [[WesternAnimation/TheOctonauts Peso]], [[Series/Miranda2009 Stevie Sutton]] and [[WesternAnimation/MattHatterChronicles Gomez]].
** (US; 1999) [[Franchise/{{Patlabor}} Kataoka]] (later [[Series/TrueJacksonVP Max Madigan]], then [[WesternAnimation/FifiAndTheFlowertots Bumble]]) is a construction worker who, along with his business partner [[WesternAnimation/{{Fantomcat}} Tabs Wildcat]], complete construction and reparation projects with their team of anthropomorphic construction vehicles, consisting of [[WesternAnimation/GerryAndersonsNewCaptainScarlet Destiny Angel]] (later WesternAnimation/HorridHenry)[[note]]Sonya Leite, Lofty's first actress, has no other notable acting credits[[/note]], [[WesternAnimation/{{Ninjago}} Dareth]] (later [[WesternAnimation/ThunderbirdsAreGo Virgil Tracy]]), [[Series/DoctorWho Trinity Wells (later Ace]]), [[WesternAnimation/RoaryTheRacingCar Roary]] and [[VideoGame/ProfessorLayton Luke Triton]].
** (US; 2015) Bumble and Tabs (now [[WesternAnimation/BeastWars Quickstrike]] and Anna Bates) move to a new location, and are joined by [[WesternAnimation/IronManArmoredAdventures War Machine]]. Their machines are now [[WesternAnimation/MyLittlePonyFriendshipIsMagic Snails, Sweetie Belle]], Neil Sutherland, [[WesternAnimation/{{Ninjago}} Kai]] and [[Anime/DragonBallZ Goku]], who have been joined by [[WesternAnimation/ThreeTwoOnePenguins Fidgel]] and [[WesternAnimation/StreetFighter M. Bison]].
* ''WesternAnimation/BoJackHorseman'': [[Series/ArrestedDevelopment Gob Bluth]] is the washed-up star of the sitcom ''Horsin' Around''. His agent/on-and-off girlfriend is [[WesternAnimation/ShrekTheThird Cinderella]], and his rommate is [[Series/BreakingBad Jesse Pinkman]]. His former rival in television was [[Film/ThereWillBeBlood Prescott]], while [[Series/{{Community}} Annie Edison]] is ghostwriting is autobiography.
* ''WesternAnimation/BoltsAndBlip'': [[WesternAnimation/TotalDramaPresentsTheRidonculousRace Don]] and [[Series/RookieBlue Officer Duncan Moore]] are two robots who participate in fighting tournaments alongside [[WesternAnimation/{{Arthur}} Muffy Crosswire]], their coach [[VideoGame/FarCry5 Eli Palmer]], and his assistant WesternAnimation/IggyArbuckle. [[Series/MonsterWarriors Dink Dorman]] is their rival, while the tournament announcers are [[WesternAnimation/JimmyTwoShoes Samy Garvin and General Molotov]]. The BigBad is [[WesternAnimation/AtomicBetty Maximus I.Q.]], the former colleague of [[WesternAnimation/SevenLittleMonsters Three]], the scientist who created all the robots.
* ''WesternAnimation/{{Bonkers}}'': [[WesternAnimation/TaleSpin Don Karnage]] loses his job as Wackytoon Studios' biggest cartoon star and becomes a cop. He is first partnered with [[WesternAnimation/TheLooneyTunesShow Taz]], and then later with [[WesternAnimation/BatmanTheAnimatedSeries Cassidy]].
* ''WesternAnimation/TheBoondocks'': [[Series/{{Southland}} Detective Lydia Adams]] and [[Series/TwentyFour Sandra Palmer]] are two brothers raised in the suburbs by [[Series/TheWayansBros John 'Pops' Williams]]. [[Series/Reno911 Deputy S. Jones]] is a lawyer who married [[WesternAnimation/SpongeBobSquarePants Karen]]. [[WesternAnimation/StrokerAndHoop Coroner Rick]] is a white supremacist. [[Series/TheMaryTylerMooreShow Lou Grant]] is a CorruptCorporateExecutive whose grandson, [[Series/ChappellesShow Buc Nasty]], is a [[PrettyFlyForAWhiteGuy wigger]] who spends most of his time robbing stores with his partner [[Film/PulpFiction Jules Winnfield]].
* ''WesternAnimation/TheBotsMaster'': [[Anime/MobileSuitGundamWing Heero Yuy]] leads a brigade of heroic robots against an evil MegaCorp led by [[Anime/DragonBallZ Cell]] and his subordinates [[WesternAnimation/BeastWars Cheetor]] and [[WesternAnimation/EdEddNEddy Sarah]]. The robots working for Heero include the likes of [[WesternAnimation/ReBoot Mike the TV]], [[Franchise/DragonBall Krillin]], and [[WesternAnimation/EdEddNEddy Double D]].
* ''WesternAnimation/BoyGirlDogCatMouseCheese'': [[WesternAnimation/TheFungies Nevin]],[[Anime/YuGiOhZexal Rio Kastle]], [[Anime/PokemonTheSeries Mantle]], [[TheVoiceless a cat]], [[WesternANimation/WinxClub Orlando]], and [[VideoGame/SonicRush Blaze the Cat]] have all become stepsiblings and must learn to get along.
* ''WesternAnimation/{{Braceface}}'': [[Film/{{Clueless}} Cher Horowitz]] (later [[WesternAnimation/{{Sixteen}} Nikki Wong]]) is a teenage girl with braces that effect her ordinary life in strange ways. Her friends are [[WesternAnimation/JoJosCircus Peaches]] and [[WesternAnimation/MyFriendRabbit Rabbit]], and [[Anime/SailorMoon Tuxedo Mask]] is her crush, whose best friend is [[WesternAnimation/TheMagicSchoolBus Carlos]]. [[WesternAnimation/TotallySpies Alex]] is the AlphaBitch whose sidekick is [[WesternAnimation/AnneOfGreenGablesTheAnimatedSeries Diana Barry]]. Cher/Nikki's mother is [[WesternAnimation/XMenTheAnimatedSeries Mystique]], and her brothers are [[WesternAnimation/TotalDrama Geoff]] and Film/{{Scott Pilgrim|VsTheWorld}}.
* ''WesternAnimation/BrandyAndMrWhiskers'': [[Series/TheBigBangTheory Penny]] is a pampered poodle whose life changes when she ends up stuck in the Amazon with [[WesternAnimation/AaahhRealMonsters Ickis]]. The two get into many shenanigans together in their new home, and make friends with such creatures as [[WesternAnimation/TransformersAnimated Starscream]], [[VideoGame/ScarfaceTheWorldIsYours Tony Montana]], [[WesternAnimation/BatmanTheAnimatedSeries Batgirl]], [[WesternAnimation/WelcomeToTheWayne Ansi Molina]], [[VideoGame/MassEffect Female Commander Shepard]], and [[WesternAnimation/MadagascarEscape2Africa Florrie the Lion]].
* ''Franchise/{{Bratz}}'': Series/PunkyBrewster, one of the twins from ''Series/SisterSister'', [[WesternAnimation/AvatarTheLastAirbender Ty Lee]], and [[WesternAnimation/TheFairlyOddParents Trixie Tang]] run a fashion magazine and do stuff, usually against antagonists [[Series/TheBigBangTheory Penny]] and [[WesternAnimation/TheWildThornberrys Eliza Thornberry]], who both work for [[Series/JustShootMe Nina Van Horn]]. [[Videogame/FinalFantasyX2 Buddy]], WesternAnimation/KickButtowski, and [[WesternAnimation/TheEmperorsNewSchool Malina]] are supporting characters.
* ''WesternAnimation/{{Breadwinners}}'': [[WesternAnimation/OKKOLetsBeHeroes Raymond]] and [[WesternAnimation/{{Unikitty}} Master Frown]] are ducks who work for a bread-delivering company. [[WesternAnimation/TeenTitans2003 Control Freak]] is the ducks' pet frog, [[WesternAnimation/AskTheStorybots Bang]] is a legendary creature who lives in the bread mines, [[WesternAnimation/TheFairlyOddParents Chloe Carmichael]] is a mechanic that they occasionally seek advice from, [[VideoGame/KidIcarusUprising Hades]] is their best customer, and [[VideoGame/{{Skylanders}} Stealth Elf]] is a police officer who dislikes them.
* ''WesternAnimation/{{Brickleberry}}'': [[WesternAnimation/KingOfTheHill Buckley]] works at a national park run by WesternAnimation/SpongeBobSquarePants. His co-workers include [[Series/LuckyLouie Walter]], [[CreatorCameo the show's creator]], and [[Series/ItsAlwaysSunnyInPhiladelphia Dee]] (later [[WesternAnimation/UglyAmericans Callie]]). Creator/DanielTosh is a talking bear.
* ''WesternAnimation/TheBrothersFlub'': [[WesternAnimation/TeenTitans2003 Robin]] and [[Film/{{Godspell}} Jerry]] are brothers who work for a delivery company run by [[Series/GirlMeetsWorld Grammy Hart]].
* ''WesternAnimation/{{Bubsy}}'': Obnoxious bobcat [[WesternAnimation/{{Animaniacs}} Dr. Otto Scratchensniff]] volunteers to test a virtual reality helmet invented by [[WesternAnimation/WildWestCOWBoysOfMooMesa Marshall Moo Montana]]. They are accompanied by Otto's pet armadillo [[WesternAnimation/RainbowBrite Lurky Dismal]], his niece and nephew [[WesternAnimation/ScoobyDooAndTheAlienInvaders Velma Dinkley]] and [[WesternAnimation/{{Futurama}} Tinny Tim]], and Marshall Moo's assistant [[WesternAnimation/VeggietalesInTheHouse Junior Asparagus]]. [[WesternAnimation/ScoobyDooAndTheReluctantWerewolf Repulsa]] sends her henchmen [[WesternAnimation/KungFuPandaLegendsOfAwesomeness Constable Hu]] and [[WesternAnimation/BumpInTheNight Mr. Bumpy]] to steal the helmet for herself.
* ''WesternAnimation/BumpInTheNight'': WesternAnimation/{{Cat|Dog}} is a small green monster who lives under the bed of a 10-year-old boy with his best friend [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Principal Willabee]]. Other characters include [[WesternAnimation/ThePowerpuffGirls Grubber]], [[Anime/LoveLive Cocoa Yazawa]], [[WesternAnimation/TomAndJerryTheMovie Robyn Starling]], [[WesternAnimation/FindingNemo Bloat]], and [[WesternAnimation/{{Rugrats}} Tommy Pickles]].
* ''WesternAnimation/ButtUglyMartians'': [[WesternAnimation/PetAlien Tommy Cadle]], [[WesternAnimation/DocMcStuffins Chilly the Snowman]], and [[WesternAnimation/{{Catscratch}} Gordon]] are a team of crime-fighting martians who regularly foil the evil plans of their leader [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius King Goobot]]. Joining them are [[WesternAnimation/DextersLaboratory Dexter's Mom]], [[WesternAnimation/{{Animaniacs}} Yakko Warner]], [[WesternAnimation/TheLifeAndTimesOfJuniperLee Ray-Ray]], and [[WesternAnimation/UltimateSpiderMan2012 Miles Morales]], while [[Series/TheUntouchables Eliot Ness]] is a martian hunter sent to exterminate them.
* ''WesternAnimation/BuzzLightyearOfStarCommand'': [[WesternAnimation/TheEmperorsNewGroove Kronk]] dons a spacesuit and sets out to save the universe. Joining him are [[WesternAnimation/CloneHigh Joan of Arc]], [[WesternAnimation/RoadRovers Sport]], and [[Series/{{Scrubs}} The Janitor]] (sometimes [[Film/PrettyWoman Mr. Hollister]]). They defend the galaxy from the likes of {{WesternAnimation/Batman|TheBraveAndTheBold}}, [[WesternAnimation/ToyStory2 Al]], [[WesternAnimation/{{Freakazoid}} Roddy MacStew]], [[WesternAnimation/{{Hercules}} Pain]], and [[WesternAnimation/TheHunchbackOfNotreDameDisney Judge Claude Frollo]]. In the pilot movie, Kronk was [[Series/HomeImprovement Tim "the Toolman" Taylor]].
* ''WesternAnimation/TheBuzzOnMaggie'': [[WesternAnimation/TheLoudHouse Lucy Loud]] is a preteen housefly whose parents are [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Captain K'nuckles]] and [[WesternAnimation/PepperAnn Aunt Janie Diggety]]. Her siblings are [[WesternAnimation/BackToTheFuture Marty McFly]], [[WesternAnimation/{{Gargoyles}} Lexington]], and [[WesternAnimation/TeenTitans2003 Raven]]. Her best friend at school is [[WesternAnimation/MyLifeAsATeenageRobot Tiff Crust]] while her rival is [[VideoGame/BatmanArkhamCity Harley Quinn]].
!!C
* ''WesternAnimation/CadillacsAndDinosaurs'': In a post-apocalyptic future where dinosaurs once again rule the Earth, mechanic [[Series/FXTheSeries Rick Forsythe]] and ambassador [[Anime/SailorMoon Sailor Jupiter]] struggle against a variety of foes, notably a power-hungry council composed of [[WesternAnimation/{{Babar}} Queen Celeste]], [[WesternAnimation/{{Cyberchase}} Motherboard]], and [[WesternAnimation/RoliePolieOlie Baxter Bevel]].
* ''WesternAnimation/{{Caillou}}'': [[WesternAnimation/{{Franklin}} Harriet Turtle]] (later [[Series/FifteenLove Megan O'Connor]] and then [[WesternAnimation/DragonHunters Zaza]]) explores their world and has vivid imagination sequences.
** (puppet segments): [[WesternAnimation/TheAdventuresOfTeddyRuxpin The Wooly What's-It,]] [[Series/UnderTheUmbrellaTree Iggy Iguana]], [[Series/TheNoddyShop Rusty the Tin Clown and Warloworth Q. Weasel]] discover the world around them.
* ''WesternAnimation/CampLakebottom'': [[Anime/{{Bakugan}} Dan Kuso]], WesternAnimation/PippiLongstocking, and [[WesternAnimation/{{Sixteen}} Darth Mall]] attend a creepy summer camp run by [[WesternAnimation/JohnCallahansQuads Blazer]], [[WesternAnimation/RoliePolieOlie Percy Polie]], and [[WesternAnimation/YinYangYo Eradicus]]. Their archenemies are rich kid [[WesternAnimation/TotalDrama Noah]] and Dan's sister [[WesternAnimation/AnneOfGreenGablesTheAnimatedSeries Anne Shirley]].
* ''WesternAnimation/CampLazlo'': [[WesternAnimation/TheFairlyOddParents Mr. Crocker]] is a fun-loving boy scout at a summer camp run by [[WesternAnimation/TheBatman the Penguin]] and [[WesternAnimation/TeenTitans2003 Mumbo]]. Other people at the camp are [[WesternAnimation/DextersLaboratory Dexter's dad]], [[WesternAnimation/ElTigre Puma Loco]], [[WesternAnimation/SpongebobSquarepants Larry the Lobster]], [[WesternAnimation/TheLandBeforeTime Petrie]], [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Dr. Barber, Lolly Poopdeck]], [[WesternAnimation/RockosModernLife Filburt]], [[WebAnimation/MightyMagiswords Ralphio]], [[WesternAnimation/AdventureTime Peppermint Butler, Duke of Nut]], [[WesternAnimation/SecretMountainFortAwesome Slog]], [[WesternAnimation/RegularShow Spacey McSpacetree]], [[WesternAnimation/CodenameKidsNextDoor Mr. Boss]], and [[WesternAnimation/SamuraiJack Scaramouche]]. [[WesternAnimation/CatDog Lube]] is the camp cook, while [[WesternAnimation/SpongebobSquarepants Plankton]] is the nurse. WesternAnimation/JohnnyBravo and [[WesternAnimation/TheLifeAndTimesOfJuniperLee Monroe]] appear as lifeguards in one episode. [[WesternAnimation/ToyStory2 Barbie]], who attends the girls' camp, has a crush on Crocker while The Penguin sports one on [[WesternAnimation/TheLittleMermaid1989 Ariel]], the head of the girls' camp, which is also attended by [[WesternAnimation/SpongebobSquarepants Karen]], [[WesternAnimation/TheLoudHouse Rita Loud]], [[WesternAnimation/BaltoIIWolfQuest Jenna]], [[WesternAnimation/IceAge Roshan]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]], and [[VideoGame/TheWonderful101 Wonder-Pink]]. Ariel's assistant is [[WesternAnimation/TheBoondocks Sarah Dubois]]. Barbie turns out to be the daughter of the Penguin's boss [[WesternAnimation/ThePowerpuffGirls Grubber]]. Larry's older brothers are WesternAnimation/SpongeBobSquarePants, [[WesternAnimation/FostersHomeForImaginaryFriends Eduardo]], [[WesternAnimation/ClassOf3000 Principal Luna]], and [[WesternAnimation/PenguinsOfMadagascar Kowalski]]. [[spoiler:In the final episode, it turns out that the Penguin impersonated the real Scoutmaster [[WesternAnimation/MyGymPartnersAMonkey Jake Spidermonkey]].]]
* ''WesternAnimation/CaptainCavemanAndTheTeenAngels'': WesternAnimation/DaffyDuck is a prehistoric superhero who solves mysteries with [[Series/TheFreshPrinceOfBelAir Viola "Vy" Smith]], [[WesternAnimation/ScoobyDooAndTheGhoulSchool Winnie Werewolf]], and [[WesternAnimation/MyLittlePonyTheMovie1986 Sweet Stuff]].
* ''WesternAnimation/CaptainFlamingo'': [[WesternAnimation/MyLittlePonyPonyLife Spike]] is a kid superhero who helps other children solve their problems with the help of his best friend sidekick [[WesternAnimation/DiGataDefenders Maia]]. Other characters include over-protective only child [[WesternAnimation/PeepAndTheBigWideWorld Peep]], smart and sophisticated [[WesternAnimation/MyFriendRabbit Coral]], disaster-making [[WesternAnimation/OddJobJack Bobby Lee]], Spike's cousin nemesis [[WesternAnimation/RoliePolieOlie Olie]], Maia's rival [[WesternAnimation/{{Cyberchase}} Inez]], smart and constantly freaking out [[WesternAnimation/MissSpidersSunnyPatchFriends Shimmer]], easily distracted [[WesternAnimation/{{Braceface}} Sharon Spitz]], wacky genius [[WesternAnimation/XMenTheAnimatedSeries Jean Grey]], sweet girl [[Series/NaturallySadie J.P.]] (later [[WesternAnimation/CareBearsBigWishMovie Wish Bear]]), Spike's baby brother [[WesternAnimation/MyBigBigFriend Yuri]], and Spike's mom and dad are [[WesternAnimation/JoJosCircus Dr. Seltzer]] and [[WesternAnimation/BlazingDragons Cinder]]. [[WesternAnimation/RubyGloom Scaredy Bat]] is the show's narrator.
* ''WesternAnimation/CaptainNTheGameMaster'': WesternAnimation/{{Ed|EddNEddy}} is thrust into the video game world, where he becomes the personal protector of Princess [[WesternAnimation/MyLittlePonyTales Patch]]. With the assistance of [[Anime/MobileSuitGundamSeed Patrick Zala]], [[Manga/DragonBall Oolong]], [[Manga/DeathNote L Lawliet]], and later [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Goddard]], Ed fights the evil forces of [[Manga/RanmaOneHalf Ryoga Hibiki]], [[WesternAnimation/AdventuresOfSonicTheHedgehog Grounder]], [[WesternAnimation/BabyLooneyTunes the Tasmanian Devil]], and [[Film/LittleShopOfHorrors Audrey II]].
* ''WesternAnimation/CaptainPlanetAndThePlaneteers'': Our world is in peril. [[Series/StarTrekTheNextGeneration Guinan]]/ [[Film/SupermanFilmSeries Lois Lane]], the spirit of Earth, can no longer stand the terrible destruction plaguing our planet. She gives five special rings to five special young people. From Africa, [[Series/Roots1977 Kunta Kinte]] with the power of earth. From North America, [[WesternAnimation/CartoonAllStarsToTheRescue The Drug Dealer]] with the power of fire. From the Soviet Union/Eastern Europe, [[WesternAnimation/{{Rugrats}} Lil Deville]] with the power of wind. From Asia, [[WesternAnimation/MyLifeAsATeenageRobot Jenny "XJ-9" Wakeman]] with the power of water. And from South America, [[WesternAnimation/TeenTitans2003 Robin]] with the power of heart. With the five powers combined they summon earth's greatest champion - [[WesternAnimation/PolePosition DANIEL DARRET]]! In addition, the villains include [[WesternAnimation/MonstersInc Henry Waternoose]] / [[WesternAnimation/TaleSpin Baloo]], [[Franchise/JurassicPark Ian Malcolm]] / [[WesternAnimation/PinkyAndTheBrain The Brain]], [[Series/TheWestWing President Bartlet]] / [[WesternAnimation/ChalkZone Skrawl]], [[Film/WhenHarryMetSally Sally]] / [[WesternAnimation/SouthPark Liane Cartman]], and [[Film/TheRockyHorrorPictureShow Frank N. Furter]].
* ''Franchise/CareBears''
** ''WesternAnimation/CareBears1980s'': WesternAnimation/{{Rudolph|TheRedNosedReindeer1964}} (later [[WesternAnimation/TheDevilAndDanielMouse Daniel Mouse]]), [[WesternAnimation/{{Wayside}} Miss Mush]], [[WesternAnimation/StickinAround Ms. Mobley]], [[WesternAnimation/WildKratts Donita Donata]], [[WesternAnimation/{{Ewoks}} Shodu Warrick]], [[WesternAnimation/TheRaccoons Ralph Raccoon]], [[WesternAnimation/KidVsKat Old Lady Munson]], [[WesternAnimation/InspectorGadget Chief Quimby]], [[WesternAnimation/LittleBear Mother Bear]], [[WesternAnimation/RoliePolieOlie Bonita Bevel]], and [[WesternAnimation/LetsGoLuna Lucie Hopper]] are colorful bears from the land of Care-a-lot who help childen in need of caring while also foiling the evil plans of [[WesternAnimation/DonkeyKongCountry Krusha]] and later [[WesternAnimation/{{Dinosaucers}} Dimetro]] and his henchmen [[WesternAnimation/{{Redwall}} Cap'n Clogg]] and [[WesternAnimation/FlyingRhinoJuniorHigh Lydia Lopez]].
** ''WesternAnimation/CareBearsWelcomeToCareALot'': [[Manga/{{Naruto}} Jiraiya]], [[VideoGame/FinalFantasyVIII Squall]] [[VideoGame/DissidiaFinalFantasy Leonhart]], [[Manga/{{Bleach}} Nnoitra]], [[Manga/GirlsBravo Kirie Kojima]], [[VideoGame/BinaryDomain Rachel Townsend]], [[WesternAnimation/PeterRabbit Lily Bobtail]], and [[VideoGame/MortalKombatVsDCUniverse Catwoman]] are a bunch of colorful bears who teach lessons and morals to kids.
** ''WesternAnimation/CareBearsAndCousins'': [[Manga/MobileSuitGundamTheOrigin Denim]], [[WesternAnimation/HeyArnold Rhonda Wellington Lloyd]], [[WesternAnimation/BuddyThunderstruck Handsome Joe]], and [[Anime/YourName Taki Tachibana]] reunite with the bears.
* ''WesternAnimation/CarlSquared'': [[WesternAnimation/TheMagicSchoolBus Ralphie Tennelli]] orders a clone of himself named [[WesternAnimation/XMenTheAnimatedSeries Proteus]] to do stuff for him. His best friend [[Film/CampRock Barron James]] is the only one who knows of this clone. His girlfriend is [[WesternAnimation/AngelaAnaconda Gina Lash]], and his family includes his sister [[WesternAnimation/RubyGloom Misery]], his mother [[WesternAnimation/{{Wayside}} Mrs. Jewls]], and his dad [[Series/ThisIsWonderland Cameron Tiernay]].
* ''WesternAnimation/CarmenSandiego'': [[Series/JaneTheVirgin Jane Villanueva]] is an orphan raised by the heads of a global crime syndicate (including [[Anime/{{Naruto}} Gaara]], [[WesternAnimation/StevenUniverse Dr. Maheswaran]], [[WesternAnimation/Ducktales2017 Mrs. Beakley]], and [[VideoGame/{{Overwatch}} Hanzo]]) who has wanted to be a thief her whole life. However, she abandons the syndicate after seeing what lengths they'll go to to secure priceless artifacts, and, with help from young hacker [[Series/StrangerThings Mike Wheeler]], dedicates her life to taking them down. Along the way, she fights former classmates [[Franchise/Ben10 Charmcaster]], [[WesternAnimation/LooneyTunesCartoons Bugs Bunny]], and [[Series/OrangeIsTheNewBlack Brook Soso]], and is pursued by a French Interpol agent and his partner [[VideoGame/{{Overwatch}} D.Va]].
* ''WesternAnimation/Castlevania2017'': The vampire hunter [[Film/TheHobbit Thorin Oakenshield]], the witch [[WesternAnimation/WinxClub Flora]] and the Dhampir [[WesternAnimation/RickAndMorty Pat Gutterman]] are working together to fight the vampire [[VideoGame/DantesInferno Dante]] after he goes to a war against humanity following his wife's death.
* ''WesternAnimation/TheCatInTheHatKnowsALotAboutThat'': [[Film/ThreeAmigos Ned Nederlander]] teaches [[WesternAnimation/TotalDramaPresentsTheRidonculousRace Junior]] and [[WesternAnimation/TopWing Shelly]] about the world. They are joined by Junior and Shelly's goldfish [[WesternAnimation/TheZhuZhus Chunk]] and Ned's helpers [[WesternAnimation/AlmostNakedAnimals Howie]] and [[WesternAnimation/{{Cyberchase}} Delete]].
* ''WesternAnimation/CatDog'': [[WesternAnimation/OKKOLetsBeHeroes Lord Boxman]] and WesternAnimation/SpongeBobSquarePants (alternatively, [[WesternAnimation/TheSuperHeroSquadShow Thanos and Iron Man]]) are conjoined brothers. Recurring antagonists include [[{{WesternAnimation/Futurama}} Phillip J. Fry]], [[WesternAnimation/{{Chowder}} Mung Daal]], [[WesternAnimation/TheLooneyTunesShow Elmer Fudd]], and a gang made up of [[WesternAnimation/RockosModernLife Rocko, Heffer,]] and [[WesternAnimation/HarveyBeaks Grada]]. [[WesternAnimation/MikeLuAndOg Mike Mazinsky]], [[WesternAnimation/TheRenAndStimpyShow Stimpy]], [[VideoGame/TakAndThePowerOfJuju Jibolba]], and [[Series/TalesFromTheCrypt the Crypt Keeper]] are friends of theirs and [[WesternAnimation/CampLazlo Clam]] is their roommate. [[spoiler: [[WesternAnimation/OpenSeason Giselle]] and [[Anime/PrincessMonoke Jiko]] are Boxman and [=SpongeBob=]'s parents.]]
* ''WesternAnimation/{{Catscratch}}'': [[WesternAnimation/HouseOfMouse Jose Carioca]], [[Series/{{Seinfeld}} Newman]], and [[WesternAnimation/InvaderZim Almighty Tallest Purple]] live in a mansion with their DeadpanSnarker butler [[WesternAnimation/TheCritic Orson Welles]]. Jose has a crush on his neighbor [[WesternAnimation/{{Chowder}} Panini]], and [[Anime/TengenToppaGurrenLagann Nia Teppelin]] becomes a SixthRanger later on.
* ''WesternAnimation/{{Centaurworld}}'': In the middle of a war, [[WesternAnimation/SpiderManSpiderVerse Peni Parker]] gets separated from her best friend [[Theatre/{{Carousel}} Carrie Pipperidge]] and winds up in a fantastical world where each and every organism is a centaur. There, Peni partners up with the centaur equivalents of [[WesternAnimation/SofiaTheFirst Princess Prisma]], [[Series/HowIMetYourMother Ted Mosby]], [[WesternAnimation/TransformersRescueBots Blades]], [[WesternAnimation/TheWonderfulWorldOfMickeyMouse Mickey Mouse]], and... uh... [[DescendedCreator somebody pretty important,]] and embarks on a quest to get back home to Carrie, singing songs with her new friends along the way and learning the value of self-care and healing from trauma, but Peni eventually has to prevent a terrifying creature called [[WesternAnimation/ThePrinceOfEgypt Jethro]] from destroying both worlds.
* ''WesternAnimation/CentralPark'': [[Theatre/{{Hamilton}} Aaron Burr]] is the manager of Central Park and, alongside his family (wife [[Series/ParksAndRecreation Jennifer Barkley]], son [[Series/UnbreakableKimmySchmidt Titus Andromedon]], and daughter [[WesternAnimation/Frozen2013 Anna]] ([[TheOtherDarrin later]] [[Series/TheUmbrellaAcademy Allison Hargreeves]]), fights to save the park from the machinations of elderly heiress [[Film/TheHungerGames Caesar Flickerman]]. [[Film/BeautyAndTheBeast2017 Le Fou]] is the show's narrator.
* ''WesternAnimation/ChalkZone'': After discovering a piece of magic chalk, [[WesternAnimation/ThePowerpuffGirls Buttercup]] and [[WesternAnimation/AdventureTime Princess Bubblegum]] go into a world made entirely out of chalk drawings, where they meet one of Buttercup's greatest drawings, [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Nick Dean]], and frequently foil the evil plans of WesternAnimation/DarkwingDuck. [[WesternAnimation/FostersHomeForImaginaryFriends Cheese]] is the bully at their school and [[WesternAnimation/SpongeBobSquarePants Squidward]] is a GentleGiant who helps them out sometimes. Buttercup's parents are [[WesternAnimation/{{Animaniacs}} Wakko Warner]] and [[WesternAnimation/TheLandBeforeTime Grandma Longneck]], while Princess Bubblegum's mother is [[WesternAnimation/TheLoudHouse Luna Loud]]. [[WesternAnimation/XMenTheAnimatedSeries Colossus]] is their teacher.
* ''WesternAnimation/{{Chaotic}}'': Friends [[Anime/{{Pokemon}} Cilan, Stephan, Mallow and McGinty]] play cards in a virtual world. Cilan's favorite card is [[Anime/DragonBallZ Goku]], who he transforms into during battles.
* ''WesternAnimation/ElChavoAnimado'': [[Manga/CardcaptorSakura Syaoran Li]] is a poor orphan boy living in urban Mexico. The screwed-up neighbors in this wacky vicinity are the bum [[Manga/LupinTheThird Inspector Zenigata]], the spoiled [[Manga/{{Bleach}} Gin Ichimaru]], his equally snobby mother [[Manga/{{Naruto}} Sakura Haruno]], the witch hag [[WesternAnimation/SouthPark Sheila Broflovski]], the sassy [[WesternAnimation/BlazeAndTheMonsterMachines Starla]], the dumb [[Anime/SailorMoon Ami Mizuno]], the fat guy [[Manga/{{Naruto}} Sasuke Uchiha]], his landlord father [[Franchise/{{Digimon}} Seraphimon]], and the lazy mailman [[Anime/{{FLCL}} Commander Amarao]].
* ''WesternAnimation/ChipAndPotato'': [[WesternAnimation/TopWing Penny]] attends Kindergarten for the first time with her pet and best friend [[WesternAnimation/MyLittlePonyFriendshipIsMagic Pinkie Pie]]. Her parents are [[Series/{{Supernatural}} Donna Hanscum]] and [[Anime/MobileSuitGundamSEEDDestiny Martin DaCosta]], and her older brother is [[Series/AMillionLittleThings Danny Dixon]]. Her teacher is [[Toys/{{Bionicle}} Toa Vakama]]. The school bully is [[WesternAnimation/{{Gigantosaurus}} Leon]]. Penny's best friend's parents are [[Film/AFairlyOddMovieGrowUpTimmyTurner Mrs. Turner]] and [[WesternAnimation/TotalDramarama Chef Hatchet]].
* ''WesternAnimation/ChipNDaleRescueRangers'': [[WesternAnimation/{{Histeria}} Toast]] and [[WesternAnimation/SquirrelBoy Ranger Stu]] are part of a group of animal crimefighters, also consisting of [[WesternAnimation/TinyToonAdventures Babs Bunny]], [[WesternAnimation/TreasurePlanet Onus]], and [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Ultra Lord]] (sometimes [[Franchise/{{Transformers}} Optimus Prime]]). They often fight off an overweight feline named [[WesternAnimation/{{Balto}} Steele]], who was originally owned by [[WesternAnimation/SupermanBatmanPublicEnemies Alfred Pennyworth]], or a MadScientist named [[WesternAnimation/DarkwingDuck Herb Muddlefoot]].
* ''WesternAnimation/ChopChopNinja'': [[WesternAnimation/TrollTheTakeOfATail Jan]], [[VideoGame/AssassinsCreedII Claudia Auditore da Firenze]], [[Anime/{{Bakugan}} Dragonoid]], and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Bow Hothoof]] are a group of young ninjas who defend their dojo from villains like [[WesternAnimation/{{Detentionaire}} Lynch Webber]] and [[Anime/SamuraiPizzaCats Jerry Atric]].
* ''WesternAnimation/{{Chowder}}'': A young boy named [[WesternAnimation/BambiII Flower]] becomes the apprentice of Chef [[VideoGame/CrashBandicoot Papu Papu]], along with his wife [[WesternAnimation/TheSuperheroSquadShow Scarlet Witch]] and his assistant, [[WesternAnimation/AdventureTime Jake the Dog]]. Papu Papu's business rival is [[Film/AustinPowers Frau Farbissina]], whose apprentice, [[WebAnimation/BravestWarriors Beth]], has a massive crush on Flower. Flower is also friends with [[WesternAnimation/AquaTeenHungerForce Master Shake]] and his pet is [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Fred Fredburger]].
* ''WesternAnimation/ChucksChoice'': [[Animation/{{Tobot}} Dylan]] is a 12-year-old boy with a robot named [[WesternAnimation/LittlestPetShopAWorldOfOurOwn Manny Mouser]] who gives him choices that can alter reality - just not always as expected. Accompanying them on their adventures is the tomboy [[Anime/{{InuYasha}} Kagome Hirugashi]]. Dylan's older brother is [[WesternAnimation/EdEddNEddy Rolf]] and [[WesternAnimation/PackagesFromPlanetX Dan Zembrowsky]] is his rival.
* ''WesternAnimation/ClangInvasion'': [[WesternAnimation/{{Spliced}} Two-Legs Joe]], [[WesternAnimation/ScaredySquirrel Sally Fishlips]], and [[WesternAnimation/TheBagelAndBeckyShow Percy]] are three alien robots from Planet Clang who crash land on Earth, where they befriend twins [[WesternAnimation/TotalDrama Sierra]] and [[WesternAnimation/TheAmazingSpiez Tony Clark]]. Sierra and Tony's dog [[WesternAnimation/CreativeGalaxy Pablo]] can speak through a voice box made by the robots.
* ''WesternAnimation/{{Clarence}}'': The show's creator (later [[Series/SantaClaritaDiet Eric Bemis]]), [[Series/TheGoldbergs Adam Goldberg]], and [[WesternAnimation/FostersHomeForImaginaryFriends Eduardo]] have everyday adventures. The school bully is [[Manga/{{Bleach}} Shinji Hirako]] and Eric's mom is [[WesternAnimation/TotalDrama Izzy]], while her boyfriend is [[WesternAnimation/WeBareBears Grizz]] and their teacher is [[WesternAnimation/{{Spliced}} Patricia]].
* ''WesternAnimation/ClassOf3000'': [[WesternAnimation/CampLazlo Mr. Slinkman]], [[WesternAnimation/OzzyAndDrix Osmosis Jones]], [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Libby Folfax]], [[VideoGame/MetroidPrime Samus Aran]], [[Anime/{{Bleach}} Yuzu Kurosaki]], and [[WesternAnimation/MyLifeAsaTeenageRobot Jenny Wakeman]] are students in the music class of [[Music/OutKast the show's creator]]. [[WesternAnimation/CodenameKidsNextDoor Mr. Boss]] is the school's principal.
* ''WesternAnimation/ClassOfTheTitans'': [[Anime/{{InuYasha}} Miroku, Sango]], [[WesternAnimation/XMenEvolution Rogue]] (later [[Anime/TransformersCybertron Lori]]), [[WesternAnimation/DragonTales Ord]], [[WesternAnimation/EdEddNEddy Edd]], [[Anime/TransformersEnergon Cliffjumper]], and [[Manga/DragonBall Yamcha]] are the descendants of Greek heroes who have been brought together to defeat [[Franchise/RatchetAndClank Clank]].
* ''WesternAnimation/CleopatraInSpace'': [[Series/KnightSquad Sage]] is an Egyptian princess transported 30 thousand years into the future to an alien galaxy, where she goes on adventures with her friends [[WesternAnimation/{{Clarence}} Mary Wendell]] and [[WesternAnimation/ElenaOfAvalor Gabe Nuñez]] and her teacher [[Series/{{Heroes}} Mohinder Suresh]]. Together, they battle [[Series/TwoBrokeGirls Oleg Golishevsky]].
* ''Literature/CliffordTheBigRedDog'': [[WesternAnimation/AvatarTheLastAirbender Azula]] adopts [[Series/EightSimpleRules Paul Hennessy]], who grows to gigantic proportions due to Azula's love. Azula's parents, [[WesternAnimation/ScoobyDooMysteryIncorporated Daphne Blake]] and [[VideoGame/WorldOfWarcraft the Blood Elf]], decide to move to Birdwell Island, where Paul becomes friends with [[WesternAnimation/TheSpectacularSpiderMan Glory Grant]], [[Series/AllThat Ed]], and [[VideoGame/MetalGearSolid Liquid Snake]]. Meanwhile, Azula becomes friends with [[VideoGame/DarkForcesSaga Tavion]], [[WesternAnimation/RocketPower Sam, and Twister]]. And their neighbors are [[Anime/KikisDeliveryService Barsa]] and [[VideoGame/MonkeyIsland the Ghost Pirate LeChuck]].
** ''WesternAnimation/CliffordsPuppyDays'': It's revealed that in his youth, Paul was [[WesternAnimation/TheLifeAndTimesOfJuniperLee Juniper Lee]].
* ''WesternAnimation/CloneHigh'': Best friends Film/MacGruber, [[Series/MadTV Stuart]], and [[WesternAnimation/KimPossible Shego]] are clones of famous people attending high school alongside AlphaBitch [[Series/TheDrewCareyShow Kate O'Brien]] and JerkJock [[Series/CarolineInTheCity Cliff. Bill]] is the MadScientist who created them. Also, [[Series/{{Scrubs}} Turk]] has invented an anthropomorphic peanut, [[Series/StarTrekVoyager the EMH Mark II]] is a clinically depressed artist, [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Sheen Estevez]] is a holy carpenter with a Latino accent, and [[Series/BeverlyHills90210 Dylan McKay]] is [[RememberTheNewGuy a guy]] [[LateArrivalSpoiler who dies]]. Also, [[Franchise/BackToTheFuture Marty McFly]] is a lonely kidney.
** (2023 revival): [=MacGruber=], Shego, Kate O'Brien (now [[Series/ThreeBusyDebras Romper Debra]]), and Cliff are unfrozen after 20 years and continue attending high school alongside Bill's new batch of clones, who include [[Series/OrangeIsTheNewBlack Dominga "Daddy" Duarte]], [[WesternAnimation/TeenageMutantNinjaTurtlesMutantMayhem April O'Neil]], [[WesternAnimation/TheGreatNorth Steven Huang]], and [[Film/Ghostbusters2016 Rowan North]]. [[Series/CougarTown Ellie Torres]] is Bill's new boss.
* ''WesternAnimation/CloseEnough'': Married couple [[WesternAnimation/RegularShow Mordecai]] and [[Film/TheHive Jess]] live in a Los Angeles duplex with their daughter [[WesternAnimation/MuppetBabies2018 Summer Penguin]] and their divorced friends [[WesternAnimation/BigMouth Jay Bilzerian]] and [[WesternAnimation/SpiderManSpiderVerse Peni Parker]].
* ''WesternAnimation/CloudyWithAChanceOfMeatballs2017'': [[WesternAnimation/WinstonSteinburgerAndSirDudleyDingDong Cutty]] is an aspiring inventor with a pet monkey named [[WesternAnimation/RocketMonkeys Wally]]. He befriends a weather intern named [[WesternAnimation/{{Braceface}} Nina Harper]], whose cameraman is [[WesternAnimation/EsmeAndRoy Roy]]. Cutty's dad is [[WesternAnimation/SevenLittleMonsters Four]], and the town's mayor is [[WesternAnimation/BestEd Ed]]. Also, [[WesternAnimation/TotalDrama Chef Hatchet]] is the local police officer and [[WesternAnimation/AlmostNakedAnimals Duck]] is the mascot for a sardine company.
* ''WesternAnimation/CoconutFredsFruitSaladIsland'': [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Carl Wheezer]], [[WesternAnimation/ElTigre Rodolfo Rivera]], [[WesternAnimation/TheRenAndStimpyShow Stimpy]], Anime/SailorMoon, and [[Manga/InuYasha Sesshomaru]] are a group of friends who live on a island for fruit. [[Manga/RanmaOneHalf Ryoga Hibiki]] is a frequent rival of Carl.
* ''WesternAnimation/CodenameKidsNextDoor'': VideoGame/{{Mega Man|11}}, [[WesternAnimation/MuppetBabies2018 Baby Gonzo]], [[WesternAnimation/TeenTitans2003 Jinx]], [[WesternAnimation/StarWarsTheCloneWars Captain Rex]], and [[WesternAnimation/{{Rugrats}} Susie Carmichael]] are members of an organization of children who fight villains such as [[Anime/DigimonFusion Shoutmon]], [[WesternAnimation/CowAndChicken Dad]], [[WesternAnimation/TinyToonAdventures Elmyra]], [[Franchise/StarWars Luke Skywalker]], [[WesternAnimation/TransformersPrime Knock Out]], [[VideoGame/FireEmblemFates Takumi]], [[WesternAnimation/HouseOfMouse Mortimer Mouse]] (who becomes [[WesternAnimation/DextersLaboratory Dexter's dad]] when depowered), [[WesternAnimation/{{Animaniacs}} Baloney the Dinosaur]], [[WesternAnimation/TheLoudHouse Lana, Lola, and Lily Loud]], [[WesternAnimation/ThePowerpuffGirls1998 Mayor, Snake, Lil Arturo]], [[Franchise/ScoobyDoo Fred Jones]], [[WesternAnimation/CampLazlo Raj, Samson]], [[WesternAnimation/PhineasAndFerb Perry the Platypus]], [[WesternAnimation/GravityFalls Waddles]], [[WesternAnimation/CatDog Dog]], [[WesternAnimation/StarWarsCloneWars Obi-Wan Kenobi]], [[WesternAnimation/GuardiansOfTheGalaxy2015 Groot]], and [[WesternAnimation/SpongeBobSquarePants Squilliam Fancyson]] (who is actually [[WesternAnimation/FostersHomeForImaginaryFriends Coco]]). Susie's older sister [[WesternAnimation/AtlantisTheLostEmpire Kida]] was a former member of the organization before becoming a teenager and joining the villains. [[WesternAnimation/AmericanDad Hayley Smith]], [[WesternAnimation/TotallySpies Sam]], [[Anime/DigimonTamers Henry Wong]], [[WesternAnimation/MyLifeAsATeenageRobot Jenny Wakeman]], and [[WesternAnimation/HiHiPuffyAmiYumi Ami Onuki]] are also members of the organization as was Baby Gonzo's younger brother [[WesternAnimation/PhineasAndFerb Perry the Platypus]] before going off on his own. Mega Man's girlfriend is [[WesternAnimation/TheFairlyOddParents Vicky]] and his parents are [[WesternAnimation/EvilConCarne Boskov]] and [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Gladys]], Baby Gonzo and Perry's mother is [[WesternAnimation/MuchaLucha the Headmistress]] and their grandmother is [[WesternAnimation/TheLifeAndTimesOfJuniperLee Ophelia Ramírez]], Jinx's younger sister is WesternAnimation/{{Unikitty}} and her parents are [[WesternAnimation/{{Futurama}} Amy Wong]] and [[Series/{{Deadwood}} Mr. Wu]], Rex's baby brother is [[WesternAnimation/AvatarTheLastAirbender Appa]] and his parents are [[WesternAnimation/AmericanDragonJakeLong Jonathan Long]] and [[VideoGame/MetroidPrime Samus Aran]], and Susie and Kida's parents are [[WesternAnimation/TheClevelandShow Cleveland Jr.]] and [[WesternAnimation/DannyPhantom Valerie Grey]]. [[WesternAnimation/TheTransformers Bonecrusher]] is a KnightOfCerebus who is the father of Mortimer [[spoiler:and Boskov, who was [[Anime/DigimonFrontier Trailmon]] in his youth]].
* ''WesternAnimation/{{Committed}}'': [[Series/SchittsCreek Johnny and Moira Rose]] have three children, who are [[WesternAnimation/{{Franklin}} Skunk]], [[Series/NaturallySadie Sadie Hawthorne]], and [[WesternAnimation/RoliePolieOlie Olie Polie]]. [[WesternAnimation/ABugsLife Flik]] is their pet.
* ''WesternAnimation/CoolMcCool'': WesternAnimation/MiltonTheMonster is a hip, trenchcoat-wearing superspy who always manages to thwart villainy despite his ineptness.
* ''[[WesternAnimation/COPS1988 C.O.P.S.]]'': [[Series/TheXFiles Walt Eubanks]], [[WesternAnimation/DogCity Bugsy Vile]], [[WesternAnimation/{{Dinosaucers}} Ankylo]], [[Film/DeadRingers Leo]], [[WesternAnimation/CareBears1980s Professor Coldheart]], [[WesternAnimation/{{Babar}} Madame]], [[WesternAnimation/{{Cyberchase}} Buzz]], [[Series/AlfredHitchcockPresents Max Cantilever]], [[Series/{{Wiseguy}} Crawley]], WesternAnimation/{{Jayce|AndTheWheeledWarriors}}, [[WesternAnimation/RubyGloom Scaredy Bat]], and [[Anime/SailorMoon JunJun]] are a team of police officers who thwart the criminal enterprises of [[WesternAnimation/TheLegendOfZelda1989 Ganondorf]] and his henchmen [[Series/TheLAComplex Ron Jacobs]], [[WesternAnimation/DiGataDefenders Flinch]], [[Series/KingOfKensington Speedy]], WesternAnimation/CliffordTheBigRedDog, [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rarity]], [[WesternAnimation/LittleBear Father Bear]], [[Film/ShortCircuit2 a robotics company executive]], and [[WesternAnimation/TheRaccoons Cedric Sneer]].
* ''WesternAnimation/CornAndPeg'': [[WesternAnimation/CliffordTheBigRedDog2019 Pablo]] (formerly [[WesternAnimation/LetsGoLuna Andy Hopper]]) and [[WesternAnimation/BluesCluesAndYou Paprika]] are inspired by their TV hero [[WesternAnimation/CupcakeAndDinoGeneralServices Mayor Vicky]] to always do good around their town.
* ''WesternAnimation/CosmicQuantumRay'': [[WesternAnimation/SpongeBobSquarePants Gary the Snail]] is a superhero who teams up with [[WesternAnimation/EdEddNEddy Double D]], Anime/{{Hamtaro}}, [[WesternAnimation/MyLittlePonyFriendshipIsMagic Snails]], [[WesternAnimation/CareBearsAdventuresInCareALot Oopsy Bear]], and [[WesternAnimation/CaptainNTheGameMaster Kevin Keene]] to defeat villains like [[WesternAnimation/{{CatDog}} Cliff]] and [[WesternAnimation/CampLazlo Slinkman]].
* ''WesternAnimation/CowAndChicken'': [[WesternAnimation/TinyToonAdventures Buster Bunny]] and [[WesternAnimation/AaahhRealMonsters Ickis]] are siblings who are constantly harassed by [[WesternAnimation/SonicTheHedgehogSatAM Snively]]. Their parents are [[WesternAnimation/StarWarsTheCloneWars Captain Rex]] and [[WesternAnimation/MyLifeAsATeenageRobot Nora Wakeman]] and their best friends are [[WesternAnimation/TheSimpsons Homer Simpson]] and [[WesternAnimation/TheManyAdventuresOfWinnieThePooh Gopher]] ([[WesternAnimation/TheLooneyTunesShow Yosemite Sam]] in one episode). [[WesternAnimation/TinyToonAdventures Sweetie Pie]] is their teacher.
** ''WesternAnimation/IAmWeasel'': [[Series/StarTrekTheNextGeneration Worf]] is an intellectual celebrity, while [[WesternAnimation/RockosModernLife Ed Bighead]] is always trying to outdo him. Occasionally, Snively shows up to annoy the two.
* ''WesternAnimation/CraigOfTheCreek'': [[Film/HeroMode Nick Williams]] goes to the Creek, the woods behind his house, every day to have fun with his best friends [[WesternAnimation/StarTrekLowerDecks D'Vana Tendi]] (formerly [[WesternAnimation/{{Jellystone}} Augie Doggie]]) and [[WesternAnimation/{{Unikitty}} Brock]]. Other residents of the Creek include [[Series/{{Heroes}} Monica Dawson]], [[WesternAnimation/KungFuPandaThePawsOfDestiny Bao]], [[WesternAnimation/SheRaAndThePrincessesOfPower Glimmer]], [[WesternAnimation/LegoStarWarsAllStars Moxie]], [[WebAnimation/TrickMoon Trickshot]], [[VideoGame/{{Overwatch}} D.va]], [[WesternAnimation/TheLoudHouse Ronnie Anne Santiago]], and [[DescendedCreator the show's creators]]. Nick lives with his father [[Film/TheExpendables Hale Caesar]], his mother [[Series/KevinProbablySavesTheWorld Yvette]], and his older brother [[WesternAnimation/SamuraiJack Jack]] (who's dating [[Film/SuicideSquad2016 Katana]]); his grandparents are [[WesternAnimation/AtlantisTheLostEmpire Joshua Sweet]] and [[Series/ThirdWatch Mary Proctor]]. The kids eventually explore the Other Side of the Creek, ruled by [[WesternAnimation/TrollsTrollstopia Demo]] and his "BFF" [[WesternAnimation/KipoAndTheAgeOfWonderbeasts Wolf]], whom [[Anime/PokemonJourneysTheSeries Goh]] keeps from invading.
* ''WesternAnimation/TheCrampTwins'': [[WesternAnimation/SquirrelBoy Leon]] and [[WesternAnimation/TinyToonAdventures Fifi La Fume]] are siblings living in Soap City who constantly do [[{{Squick}} gross things]] to each other. Their parents are [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Celestia]] and WesternAnimation/{{Mega Man|RubySpears}} and they frequently hang out with [[WesternAnimation/EdEddNEddy Eddy's Brother]]. Leon also has a friend named [[WesternAnimation/LeagueOfSuperEvil Doktor Frogg]] who owns the local dump.
* ''WesternAnimation/CrashCanyon'': [[WesternAnimation/{{Sidekick}} Professor Pampelmoose]], his wife [[Series/EastboundAndDown Cassie Powers]], his kids [[WesternAnimation/{{Grojband}} Laney Penn]] and [[WesternAnimation/MyDadTheRockStar Willy Zilla]], and his cousin [[WesternAnimation/TheAdventuresOfSamAndMaxFreelancePolice Lorne]] live in a community located at the bottom of a canyon.
* ''WesternAnimation/TheCritic'': [[Series/SaturdayNightLive Tommy Flanagan, the Pathological Liar]] is New York's #3 film critic. He tries to do right by his son [[WesternAnimation/{{Rugrats}} Chuckie Finster]], but is often verbally abused by his makeup lady [[WesternAnimation/TheSimpsons Lunchlady Doris]] and his boss [[WesternAnimation/{{Squidbillies}} the Sheriff]]. He finds love with [[Series/EmptyNest Laverne Higby]]. He is good friends with [[WesternAnimation/PinkyAndTheBrain the Brain]].
* ''WesternAnimation/CrusaderRabbit'': [[WesternAnimation/InvaderZIM Ms. Bitters]] (later [[WesternAnimation/LooneyTunes Granny]]) is a rabbit who goes on crusades with her tiger sidekick.[[note]]Vern Louden, Ragland T. Tiger's voice actor, has no other credits.[[/note]]
* ''WesternAnimation/CupcakeAndDinoGeneralServices'': [[Series/MurdochMysteries Buck Christopher]] and WesternAnimation/{{Gary|AndHisDemons}} are a sibling duo who make a living by performing various odd jobs around their hometown. Their grandmother is [[Anime/{{Bakugan}} Runo Misaki]] and [[Series/MissPersona Jason]] is their uncle. [[Series/{{Letterkenny}} Coach]] is their business assistant; [[WesternAnimation/NumbChucks Woodchuck Morris]] is their rival; and [[WesternAnimation/ThreeAmigonauts Kirbie]] is the mayor of their town.
* ''WesternAnimation/TheCupheadShow'': [[VideoGame/Psychonauts2 Adam Joseph Gette]] and [[Manga/TheVampireDiesInNoTime Draluc]] get into misadventures around Inkwell Isle, occasionally being joined by their friend [[WesternAnimation/DannyPhantom Sam Manson]].
* ''WesternAnimation/CuriousGeorge'': [[WesternAnimation/ExtremeGhostbusters Eduardo Rivera]] (originally [[Series/ShamelessUS Frank Gallagher]]) narrates the adventures of [[WesternAnimation/{{Aladdin}} Abu]], a mischievous monkey who lives with WesternAnimation/JohnnyBravo.
* ''WesternAnimation/{{Cyberchase}}'': [[Anime/{{Medabots}} Rintarou Namishima]], [[WesternAnimation/TotalDrama Leshawna, and Sierra]] are three kids who team up with a cyborg bird named [[WesternAnimation/{{Aladdin}} Iago]] (later WesternAnimation/MarvinTheTapDancingHorse) to stop the evil plans of [[Franchise/BackToTheFuture Doc Brown]] and his henchmen [[WesternAnimation/DonkeyKongCountry Krusha]] (later [[WesternAnimation/StickinAround Stanley Stickler]]) and [[WesternAnimation/AlmostNakedAnimals Howie]] to rule cyberspace, which is protected by [[WesternAnimation/MissSpidersSunnyPatchFriends Spindella]] and her technician [[WesternAnimation/MyFriendRabbit Mouse]].
* ''WesternAnimation/{{Cybersix}}'': [[WesternAnimation/MyLittlePonyFriendshipIsMagic Spike]] is an android who works as a teacher by day and battles his creator [[Anime/DragonBallZ Krilin]] by night. He is helped out by his friend and co-worker [[Anime/TransformersArmada Starscream]], his student [[WesternAnimation/EdEddNEddy Sarah]], and a street urchin named [[Toys/{{Bionicle}} Jaller]]. Krilin's son and second-in-command is [[Anime/InuYasha Kohaku]], while [[Anime/DeathNote Ryuk]] is a detective.
----
* ''WesternAnimation/OneHundredAndOneDalmatiansTheSeries'': [[WesternAnimation/KingOfTheHill Bobby Hill]], [[WesternAnimation/{{Rugrats}} Phil]] [[WesternAnimation/AllGrownUp DeVille]], [[WesternAnimation/SonicTheHedgehogSatAM Sally Acorn]], and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]] go on adventures, usually thwarting the plans of [[WesternAnimation/{{Recess}} Miss Finster]]. Other foes tend to be [[WesternAnimation/XiaolinShowdown Clay Bailey]] and [[WesternAnimation/PepperAnn Milo]]. [[WesternAnimation/TheBuzzOnMaggie Pupert]], WesternAnimation/{{Dexter|sLaboratory}}, and [[WesternAnimation/XiaolinShowdown Omi]] (who left the gang after falling in love with Bobby) are all in Milo's gang. Bobby is rivals with [[WesternAnimation/{{Recess}} King Bob]]. [[WesternAnimation/HeyArnold Harold Berman]] is friends with the pups as well. They are all in the Bark Brigade, run by [[WesternAnimation/MightyDucksTheAnimatedSeries Duke L'Orange]], [[WesternAnimation/ThePowerpuffGirls1998 Ace]], and [[WesternAnimation/GoofTroop Pete]].
* ''WesternAnimation/TwoStupidDogs'': [[Film/AmericanReel Marvin Ayres]] and [[WesternAnimation/ABugsLife Dim]] are two moronic canines who have many misadventures together, often running afoul of [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Nick Dean]] and [[WesternAnimation/TomAndJerryKids Clyde Cat]]. [[WesternAnimation/{{Animaniacs}} Yakko Warner]] is a close friend of theirs, while [[Film/TransformersFilmSeries Ironhide]] and [[WesternAnimation/{{CatDog}} Cat]] are [[WesternAnimation/SecretSquirrel secret agents that star in a spy cartoon]] that airs between episodes.
* ''WesternAnimation/ThreeTwoOnePenguins'': When [[Series/{{Smallville}} Phillip Lamont]] and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Sweetie Belle]] move in with their grandmother [[WesternAnimation/XMenEvolution Destiny]], they find four porcelain penguins that turn out to be [[Manga/{{Inuyasha}} Rasetsu]], [[VideoGame/MarvelVsCapcom3 Shuram-Gorath]], WesternAnimation/{{George of the Jungle|2007}}, and [[Manga/DragonBall Master Roshi]]. Together, they fend off various villains.
* ''WesternAnimation/ThreeAmigonauts'': [[WesternAnimation/CaptainFlamingo Ruth Ann]], [[WesternAnimation/CupcakeAndDinoGeneralServices Mayor Vicky]], and [[WesternAnimation/ClangInvasion Socket]] go to a school for space cadets. [[WesternAnimation/TotalDrama Mike]] is their rival, while [[WesternAnimation/{{Mysticons}} Baron Dreadbane]] is the trio's vehicle.
* ''WesternAnimation/{{Sixteen}}'': [[ComicBook/{{Diabolik}} Eva Kant]], WesternAnimation/ScaredySquirrel, [[Series/DegrassiTheNextGeneration Officer Turner]], [[Series/DropDeadDiva Deb Dobkins]], [[WesternAnimation/RubyGloom Iris]] and [[WesternAnimation/{{Sidekick}} Trevor Troublemeyer]] hang out in a mall. Eva works for [[WesternAnimation/TimothyGoesToSchool Henry]] at a sporting goods store; Trevor dates [[WesternAnimation/CarlSquared Chloe Crashman]] for a time; Turner dates [[WesternAnimation/GirlstuffBoystuff Reanne]] and then [[WesternAnimation/JaneAndTheDragon Verbena]]; [[WesternAnimation/TimeWarpTrio Sam]] hits on Iris but later dates [[WesternAnimation/TotalDramaPresentsTheRidonculousRace Emma]]; Iris also works for [[WesternAnimation/AlmostNakedAnimals Bunny]] and [[WesternAnimation/TotalDrama Katie and Sadie]]; [[WesternAnimation/{{Birdz}} Tommy Turkey]] is Trevor and Turner's boss in Season 2; [[WesternAnimation/PeepAndTheBigWideWorld Quack]] is the mall cop; and [[Series/SchittsCreek Jocelyn Schitt]] is Deb's rival.
* ''WesternAnimation/The7D'': [[WesternAnimation/{{Amphibia}} Hop Pop]], [[WesternAnimation/WolverineAndTheXMen2009 Blob]], [[WesternAnimation/GravityFalls Sheriff Blubs]], [[WesternAnimation/{{Futurama}} Phillip J. Fry, Kif Kroker]], [[WesternAnimation/WhereonEarthisCarmenSandiego Zack]], and [[WesternAnimation/PhineasAndFerb Perry the Platypus]] protect [[WesternAnimation/BackAtTheBarnyard Abby the Cow]]'s kingdom from the evils of [[WesternAnimation/PetAlien Swanky]] and [[Series/DropDeadDiva Joyce Keck]]. [[Creator/OneSaturdayMorning Manny the Uncanny]] is Abby's hapless assistant, and [[WesternAnimation/TheFairlyOddParents the Crimson Chin]] and [[Series/StarTrekTheNextGeneration Guinan]] are magical objects. Abby's great grandmommers is [[Film/SinginInTheRain Kathy Selden]].
!!A
* ''WesternAnimation/AaahhRealMonsters'': [[WesternAnimation/TinyToonAdventures Buster Bunny]], [[WesternAnimation/DarkwingDuck Gosalyn Mallard]], and [[WesternAnimation/{{Rugrats}} Reptar]] go to a school for monsters run by [[VideoGame/Spyro2RiptosRage Ripto]] to learn how to scare people. [[WesternAnimation/HeyArnold Coach Wittenburg]] tries to prove the monsters are real, while [[WesternAnimation/TheWildThornberrys Nigel Thornberry]] criticizes Ripto's teaching skills.
* ''WesternAnimation/AbbyHatcher'': [[WesternAnimation/MaxAndRuby Ruby]], the daughter of [[Series/{{Salvation}} Karissa]] and [[WesternAnimation/{{Sixteen}} Jonesy Garcia]], has adventures around her parents' hotel with magical creatures called Fuzzlies, of which one named [[WesternAnimation/ElinorWondersWhy Ari]] is her best friend.
* ''WesternAnimation/ActionMan2000'': [[VideoGame/FatalFury Terry Bogard]] is an Extreme sports athlete with analytical powers, who, along with his friends, [[Anime/PowerpuffGirlsZ Mojo Jojo]], [[WesternAnimation/TheCrampTwins Mari Phelps]] and [[WesternAnimation/EdEddNEddy Rolf]], and his high school coach, [[Series/StargateSg1 Teal'c]], and his friend/rival, [[Film/TuckerAndDaleVsEvil Dale]] must battle against the council of Doom consisting of its leader, [[WesternAnimation/XMenEvolution Beast]], later [[WesternAnimation/TheNewAdventuresOfHeMan Skeletor]], [[Manga/DragonBall Dende]], [[WesternAnimation/EdEddNEddy Sarah]], and [[Anime/UnicronTrilogy Optimus Prime]].
* ''WesternAnimation/TheAddamsFamily1992'': [[Film/AttackOfTheKillerTomatoes Professor Mortimer Gangreen]] and [[WesternAnimation/{{Duckman}} Merv's Secretary]] live a rather creepy and kooky life with their children [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Jimmy Neutron]] and [[WesternAnimation/TheOblongs Beth Oblong]], uncle [[WesternAnimation/TomAndJerryTheMovie Captain Kiddie]], cousin [[WesternAnimation/TeenageMutantNinjaTurtles1987 Krang]], butler WesternAnimation/DarkwingDuck, and grandmother [[WesternAnimation/Thumbelina1994 Ms. Fieldmouse]]. Their neighbors are [[WesternAnimation/DannyPhantom Jack Fenton]], [[WesternAnimation/Frozen2013 Gerda]], and [[WesternAnimation/DaveyAndGoliath Davey Hansen]].
* ''WesternAnimation/AdventureTime'': [[WesternAnimation/BatmanTheBraveAndTheBold Young Robin]] and his best friend [[WesternAnimation/{{Futurama}} Bender]] go on various adventures with Princess [[WesternAnimation/TeenTitans2003 Starfire]] and battle evil foes like [[WesternAnimation/UltimateSpiderMan2012 Dr. Octopus]], [[WesternAnimation/PhineasAndFerb Vanessa Doofenshmirtz]], and [[WesternAnimation/AvatarTheLastAirbender Fire Lord Ozai]].
** Starfire's servant is [[WesternAnimation/CampLazlo Chip/Skip]].
** At the end of the second season, Starfire gets possessed by [[WesternAnimation/TeenTitans2003 Slade]] and turns into [[WesternAnimation/TeenageMutantNinjaTurtles2012 Shredder]]. After Robin and Bender exorcise her, she regresses into [[Series/BetterOffTed Rose Crisp]].
** ''[[GenderFlip Adventure Time with Fionna and Cake]]'': [[Series/{{Californication}} Becca Moody]] and her cat [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Bubbie]] have to save Prince [[Series/HowIMetYourMother Barney Stinson]] from [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Mandy]]. [[Film/SoloAStarWarsStory Young Lando Calrissian]] is a mischievous vampire.
** At the end of season 3, Robin has a crush on the daughter of [[VideoGame/DissidiaFinalFantasy Chaos]], [[VideoGame/ResonanceOfFate Leanne]].
** In an alternate universe, Robin's mother is WesternAnimation/{{Mulan}}, and his future self is [[WesternAnimation/{{Gargoyles}} Xanatos]].
** Towards the end of season 3, [[WesternAnimation/KickButtowski Jackie Wackerman]] falls in love with [[WesternAnimation/RegularShow Benson]].
** WesternAnimation/RickAndMorty are demented dukes, though the younger one is much nicer than the older one.
** [[Series/{{Scrubs}} Turk]] just really wants to be a princess.
** [[Series/StarTrekTheOriginalSeries Mr. Sulu]] wants Starfire to love him ''or else''.
** [[Series/TheOfficeUS Dwight]] is a robot swordsman and an out-classed white mage; Creed is a wandering adventurer.
** At the start of season 6, it turns out that [[spoiler:Robin's dad is]] [[WesternAnimation/KingOfTheHill Bill Dauterive]].
** [[Series/{{Girls}} Hannah Horvath]] literally wrote the book on portals.
** An Film/{{Orphan}} is a one-armed bandit from the past-turned gooey glowing green ghost [[spoiler: and one of Robin's past lives]].
** [[Film/XMenFilmSeries (Older) Mystique]] is TheVamp[=iest=] of a quintet of vampires.
** [[WesternAnimation/TheAmazingWorldOfGumball Anais]] is an assassin.
* ''WesternAnimation/AdventuresFromTheBookOfVirtues'': [[WesternAnimation/RandyCunninghamNinthGradeNinja Viceroy]], [[Franchise/ScoobyDoo Fred Jones]], [[WesternAnimation/TazMania Taz]], and [[WesternAnimation/DextersLaboratory Dexter's Mom]] help [[WesternAnimation/TheOblongs Milo Oblong]] and [[WesternAnimation/{{Futurama}} Cubert Farnsworth]] solve everyday kid problems by reading stories to teach them important lessons.
* ''WesternAnimation/TheAdventuresOfChuckAndFriends'': [[WesternAnimation/PegPlusCat Jesse]] is a young dump truck whose parents are [[WesternAnimation/PawPatrol Mr. Porter]] (later [[WesternAnimation/RubyGloom Len]]) and [[Film/DumbAndDumber Mary Swanson]] and older brother is [[Anime/{{Bakugan}} Masquerade]]. His friends include WesternAnimation/RobTheRobot, [[WesternAnimation/{{Detentionaire}} Camillio Martinez]], [[WesternAnimation/CampLakebottom Squirt]], [[WesternAnimation/SevenLittleMonsters One]], and [[WesternAnimation/TimothyGoesToSchool Fritz]].
* ''WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius'': Manga/ZatchBell is a boy genius who created his pet, [[WesternAnimation/{{Hercules}} Pegasus]]. His best friends are [[WesternAnimation/DextersLaboratory Major Glory]] and [[WesternAnimation/CloneHigh Jesús Cristo]]. [[WesternAnimation/SpongebobSquarepants Sandy Cheeks]] and [[WesternAnimation/ThePJs Calvin]] usually mock Zatch's work, while [[WesternAnimation/EvilConCarne Hector Con Carne]] is a CloudCuckoolander and [[WesternAnimation/ChalkZone Snap]] is the BadButt [[TheChewToy Chew Toy]]. [[Series/WizardsOfWaverlyPlace Cupid]] and [[WesternAnimation/TheMightyB Hillary Higgenbottom]] are Zatch's parents, [[WesternAnimation/KimPossible Mrs. Stoppable]] is their teacher, [[WesternAnimation/TimeSquad Buck Tuddrussel]] is their principal, [[WesternAnimation/SonicTheHedgehogSatAM Sally Acorn]] is a girl Zatch has a crush on, [[Franchise/WinnieThePooh Tigger]] is a superhero that Jesús idolizes (with [[VideoGame/MetalGearSolid Grey Fox]] being Tigger's archnemesis), and [[WesternAnimation/TheRenAndStimpyShow Stimpy]] is the local candy bar owner.
** Occasionally, Zatch, Pegasus, Major Glory and Jesús, often accompanied by Sandy and Calvin, have to fend off threats such as the evil alien [[VideoGame/KidIcarusUprising Hades]] (formerly [[Series/StarTrekTheNextGeneration Captain Picard]]) and his henchman [[VideoGame/YokaiWatch Mangimutt]] (formerly [[WesternAnimation/TreasurePlanet B.E.N.]]), [[WesternAnimation/TheWildThornberrys Nigel Thornberry]], a scientist who could never finish anything, his daughter [[WesternAnimation/TheOwlHouse Eda]], Zatch's failed nanobots [[WesternAnimation/TheFairlyOddparents Cosmo]] and [[WesternAnimation/TransformersAnimated Starscream]], intergalactic game show host [[Franchise/ToyStory Buzz Lightyear]], space bandits [[WesternAnimation/MyLittlePonyFriendshipIsMagic Chancellor Neighsay]], [[WesternAnimation/CampLazlo Raj]] and [[WesternAnimation/MyLifeAsATeenageRobot Armaggedroid]], junk salesman [[WesternAnimation/CowAndChicken Red Guy]], SpoiledBrat [[WesternAnimation/TeenageMutantNinjaTurtles2012 Donatello]], evil baby [[Series/{{Seinfeld}} Alec Berg]], brainwashing granny [[WesternAnimation/TheLittleMermaid1989 Carlotta]], and MadScientist [[WesternAnimation/{{Animaniacs}} Baloney the Dinosaur]].
** ''WesternAnimation/PlanetSheen'': After borrowing one of Zatch's rockets, Jesús crash-lands on Planet Zeenu, which is ruled by emperor [[Manga/{{Naruto}} Gato]]. He also befriends a chimpanzee who crashed on the planet years ago named [[WesternAnimation/{{Chowder}} Mr. Fugu]], meets an alien named [[WesternAnimation/PinkyAndTheBrain Pinky]], [[SuspiciouslySimilarSubstitute who is almost exactly like Major Glory]], falls in love with Series/PunkyBrewster, and keeps away from [[WesternAnimation/FostersHomeForImaginaryFriends Coco]], the two-faced daughter of the emperor. Meanwhile, [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Peppermint Larry]] schemes to kill Jesús, along with his sidekick [[Film/TheHitchhikersGuideToTheGalaxy2005 Eddie the shipboard computer]].
* ''WesternAnimation/TheAdventuresOfPussInBoots'': [[WesternAnimation/WabbitALooneyTunesProduction Pepé Le Pew]] protects the village of San Lorenzo, which is inhabited by [[Film/EpicMovie Lucy]], [[WesternAnimation/TheLionGuard Bunga]], [[WesternAnimation/FostersHomeForImaginaryFriends Coco]], [[WesternAnimation/WhatsNewScoobyDoo Daphne Blake]], and WesternAnimation/{{Freakazoid}}. The mayor is [[WesternAnimation/CampLazlo Lazlo]].
* ''WesternAnimation/TheAdventuresOfSamAndMaxFreelancePolice'': [[WesternAnimation/TheSuperMarioBrosSuperShow King Koopa]] and [[WesternAnimation/{{Pelswick}} Pelswick Eggert]] work as private investigators. Their allies include their mysterious agent [[WesternAnimation/LittleBear Father Bear]], pint-sized genius Anime/SailorMoon, and an extremely clingy fan of the duo named [[Series/TheRedGreenShow Harold Green]].
* ''WesternAnimation/AdventuresOfSonicTheHedgehog'': [[Series/FamilyMatters Steve Urkel]] is a speedy hedgehog who works with his friend [[Series/{{Rubicon}} Grant Test]] to stop the schemes of [[WesternAnimation/ReBoot Old Man Pearson]] and his minions [[Manga/ZatchBell Professor Takamine]], [[WesternAnimation/BeastWars Optimus Primal]], and [[Manga/DragonBall Goku]]. [[Manga/InuYasha Suikotsu]] tries to sell them stuff. Old Man Pearson was [[Franchise/WinnieThePooh Tigger]] in the pilot.
* ''WesternAnimation/AdventuresOfTheGummiBears'': A group of bears, consisting of [[WesternAnimation/WackyRaces Dick Dastardly]], WesternAnimation/GeorgeOfTheJungle (later [[WesternAnimation/HouseOfMouse Ludwig Von Drake]]), [[WesternAnimation/LooneyTunes Witch Hazel]], ComicStrip/{{Garfield}}, [[WesternAnimation/MuppetBabies1984 Baby Rowlf the Dog]], and [[WesternAnimation/TheSmurfs1981 Slouchy Smurf]], help a squire who is initially [[Music/TheAquabats The MC Bat Commander]] (but later becomes [[WesternAnimation/TheLegendOfKorra Mako]], then [[WesternAnimation/TheFairlyOddParents Chester McBadbat]], and finally [[WesternAnimation/TaleSpin Kit Cloudkicker]]) defend his home kingdom from a pack of ogres led by Radio/TheLoneRanger. [[WesternAnimation/TheLionKing1994 Adult Simba's singing voice]] sings the theme song.
* ''WesternAnimation/TheAdventuresOfTintin1991'': [[Anime/SailorMoon Andrew Foreman]] is a young reporter who goes on adventures with his pet [[WesternAnimation/{{Birdz}} Eddie Storkowitz]], sea captain [[WesternAnimation/XMenTheAnimatedSeries Master Mold]], AbsentMindedProfessor [[Series/TheRedGreenShow Mike Hamar]], and twin detectives [[WesternAnimation/TheAdventuresOfSuperMarioBros3 Bully Koopa and Toad]].
* ''WesternAnimation/AladdinTheSeries'': [[Series/FullHouse Steve Hale]] is a street urchin engaged with Princess [[Film/{{Joshua}} Karen Danforth]]. The two go on adventures with their companions [[WesternAnimation/TheSimpsons Barney Gumble]], [[WesternAnimation/{{Cyberchase}} Digit]], and WesternAnimation/CuriousGeorge, fighting villains such as [[WesternAnimation/ThePowerpuffGirls Fuzzy Lumpkins]], [[WesternAnimation/{{Dilbert}} Catbert]], [[WesternAnimation/CowAndChicken Chicken]], [[WesternAnimation/TaleSpin Baloo]], [[WesternAnimation/{{Rugrats}} Chas Finster]], and [[Series/{{Cheers}} Lilith Sternin]]. [[Film/{{Ladybugs}} Matthew]] ([[WesternAnimation/CampLazlo Raj]] in one episode) is an evil wizard and [[ShadowArchetype Steve's opposite]]. [[Series/StarTrekDeepSpaceNine Odo]] is an Egyptian-themed Imp and conman.
* ''Literature/AlexanderAndTheTerribleHorribleNoGoodVeryBadDay'' [- (1990 AnimatedAdaptation) -]: [[WesternAnimation/TheMagicSchoolBus Arnold Perlstein]] has a terrible day. [[Theatre/ThePhantomOfTheOpera Raoul de Chagny]] and [[Film/SleeplessInSeattle Loretta]] are his parents, and [[AnimatedMusical they all sing songs]] by the composer of ''Theatre/ByeByeBirdie''.
* ''WesternAnimation/AllHailKingJulien'': [[WesternAnimation/MilesFromTomorrowland Admiral Watson]] is made king of the lemurs by his uncle [[Series/HappyDays the Fonz]]. He rules with the help of [[WesternAnimation/LoonaticsUnleashed Tech E. Coyote]], [[Film/RunFatboyRun Maya]], and [[WesternAnimation/JusticeLeagueAction Chronos]]. His subjects include WesternAnimation/JohnnyBravo, [[WesternAnimation/ThePowerpuffGirls Ace]], [[Film/LooneyTunesBackInAction Foghorn Leghorn]], [[WesternAnimation/StarVsTheForcesOfEvil Coblat]], [[Anime/TheCatReturns Natoru]], and [[WesternAnimation/BuzzLightyearOfStarCommand Warp Darkmatter]]. [[WesternAnimation/{{Chowder}} Mung Daal]] is a recurring villain.
* ''WesternAnimation/AlmostNakedAnimals'': [[WesternAnimation/{{Cyberchase}} Delete]] manages a hotel with his best friend [[WesternAnimation/JacobTwoTwo Leo Louse]]. Other staff members include [[Anime/{{Bakugan}} Alice Gehabich]], [[WesternAnimation/RocketMonkeys YAY-OK]], [[WesternAnimation/JimmyTwoShoes Lucius Heinous VII]], [[WesternAnimation/SevenLittleMonsters Four]], and [[WesternAnimation/ScaredySquirrel Sally Fishlips]]. Their business rival is [[WesternAnimation/{{Grojband}} Trina Riffin]] and her sidekick [[Series/{{Wilbur}} Wilbur the Calf]]. Also, [[WesternAnimation/TotalDrama Chris McLean]] is a stuntman that Delete idolizes.
* ''Comicbook/TheAmazingScrewOnHead'': [[Film/ShootEmUp An unkempt assassin]] and his BattleButler [[WesternAnimation/{{Ratatouille}} Remy]] must save the world from his ex-BattleButler zombie [[Film/Hellboy2004 Abe Sapien]].
* ''WesternAnimation/TheAmazingWorldOfGumball'': [[WesternAnimation/YoungJustice2010 Beast Boy]] (WesternAnimation/{{Chowder}} in the pilot; [[Series/TheGoldbergs Chad Kremp]] in Seasons 3-5; [[WesternAnimation/LEGOStarWarsTheFreemakerAdventures Rowan Freemaker]] in Seasons 5-6) gets into various highjinks with his family and friends, usually with his goldfish-turned-brother [[WesternAnimation/TheLooneyTunesShow Gossamer]] ([[Theatre/{{Matilda}} Nigel]] in the pilot; [[Series/TheWhispers Ethan]] in Seasons 3-5; [[Series/{{Containment}} Thomas]] in Seasons 5-6; [[WesternAnimation/{{TOTS}} Freddy]] in Season 6), his sister [[WesternAnimation/AdventureTime Me-Mow]] or his parents [[WesternAnimation/RainbowRangers Preston Praxton]] and [[VideoGame/XenobladeChronicles2 Queen Raqura]]. [[WesternAnimation/ThomasAndFriends Diesel]] works in every job. [[Film/ThePhantomMenace Sebulba]] was several supporting characters in the first season. Also, Santa Claus leads a double life as an AxCrazy [[WesternAnimation/{{Tarzan}} hunter]] named [[WesternAnimation/PeppaPig Grampy Rabbit]].
* ''WesternAnimation/AmericanDad'': [[WesternAnimation/TheClevelandShow Tim the Bear]] is a government agent working for [[Series/StarTrekTheNextGeneration Captain Picard]]. He is married to [[Film/{{Innerspace}} Wendy]] and has two kids named [[Series/{{ER}} Dr. Archie Morris]] and [[WesternAnimation/CodenameKidsNextDoor Numbuh 362]], an alien named [[WesternAnimation/FamilyGuy Brian Griffin]], and a German fish named [[WesternAnimation/SpongeBobSquarePants Bubble Bass]]. Two of Morris's friends are [[Film/RevengeOfTheNerds Booger]] and [[Film/AmericanPie Finch]].
* ''WesternAnimation/AmericanDragonJakeLong'': [[WesternAnimation/AvatarTheLastAirbender Prince Zuko]] is an Asian-American teenager who can transform himself into a dragon. His grandfather, [[WesternAnimation/HiHiPuffyAmiYumi Kaz]], is his mentor and [[WesternAnimation/AdventureTime Jake the Dog]] joins him. His parents are [[WesternAnimation/{{Futurama}} Amy Wong]] and WesternAnimation/JohnnyBravo and his sister is [[Series/PhilOfTheFuture Pim Diffy]]. He later has a complicated relationship with [[WesternAnimation/TheOwlHouse Amity Blight]].
* ''WesternAnimation/{{Amphibia}}'': [[Series/TheSuiteLifeOfZackAndCody London Tipton]] is magically transported to a world inhabited by frogs, where she befriends [[WesternAnimation/MilesFromTomorrowland the second Miles Callisto]], who lives in the town of Wartwood with his grandfather WesternAnimation/{{Goofy}} and little sister [[WesternAnimation/ThePowerpuffGirls2016 Blossom]]. However, London's friends, [[WesternAnimation/BigCityGreens Gloria]] and [[WesternAnimation/ArloTheAlligatorBoy Alia]], have also been transported to the same world and have teamed up with [[Anime/SoulEater Excalibur]] and [[WesternAnimation/ThePrincessAndTheFrog Dr. Facilier]] respectively. The denizens of Wartwood include the mayor [[WesternAnimation/KingOfTheHill Bill Dauterive]] and his sidekick WesternAnimation/{{Wander|OverYonder}}, spooky kid [[Series/OneMississippi Jessie]] and her triplet sisters [[Series/SingleParents Sophie Cooper]] and [[Series/TheReallyLoudHouse Lana and Lola Loud]], resident nutjob [[Franchise/KingdomHearts Xigbar]], and Miles' crush [[WesternAnimation/{{Storks}} Tulip]], who is the daughter of [[Anime/{{Aggretsuko}} Retsuko's mother]] and the granddaughter of [[Anime/DigimonTamers Terriermon]].
* ''WesternAnimation/AngelaAnaconda'': The creator of ''WesternAnimation/PepperAnn'' is rivals with AlphaBitch [[WesternAnimation/{{Franklin}} Badger]], who is the TeachersPet of [[WesternAnimation/BlazingDragons Sir Blaze]]. Her friends are WesternAnimation/ElliotMoose, [[WesternAnimation/TotalDrama Samey]], and [[Anime/{{Dangaioh}} Roll Kran]].
* ''WesternAnimation/TheAngryBeavers'': [[WebAnimation/HelluvaBoss Crimson]] and [[WesternAnimation/OKKOLetsBeHeroes a warlock]] are brothers who have many misadventures in their Northern Oregon home. [[VideoGame/BatmanArkhamAsylum The Riddler]] and [[VideoGame/StarWarsTheOldRepublic Karrels Javis]] are friends of theirs and [[Series/{{Friends}} Jasmine]] is the warlock's girlfriend.
* ''WesternAnimation/{{Animaniacs}}'': [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Carl Wheezer]], [[WesternAnimation/TwoStupidDogs Secret Squirrel]], and [[WesternAnimation/AdventuresOfTheGummiBears Lady Bane]] are a trio of cartoon siblings who run amuck pestering people. [[WesternAnimation/TheCritic Jeremy Hawke]] is a gangster pigeon, [[Theatre/AnnieGetYourGun Annie Oakley]] and [[Franchise/ScoobyDoo Fred Jones]] are a homeless cat and dog, [[WesternAnimation/TheSimpsons Bart Simpson]] is a happy-go-lucky toddler who causes her dog [[WesternAnimation/TinyToonAdventures Gogo Dodo]] a lot of grief, [[WesternAnimation/MyGymPartnersAMonkey Principal Pixiefrog]] and [[WesternAnimation/DannyPhantom Jack Fenton]] are [[WesternAnimation/PinkyAndTheBrain two lab rats who constantly plot to]] TakeOverTheWorld, and [[Series/LittleHouseOnThePrairie Rachel Brown Oleson]] and [[WesternAnimation/{{Histeria}} Froggo]] are cartoon squirrels.
** ''WesternAnimation/Animaniacs2020'': Carl, Secret, and Bane are back for more cartoon antics.
** [[WesternAnimation/TheTransformers Megatron]] doesn't like the trio turning up behind him all of a sudden and tells them not to do that. However, Carl tells them not to ask them, but to ask [[WesternAnimation/DaveTheBarbarian Chuckles the Silly Piggy]] instead.
* ''WesternAnimation/AnneOfGreenGablesTheAnimatedSeries'': [[WesternAnimation/ToadPatrol Oyster]] lives in Avonlea, Canada with her adopted parents [[WesternAnimation/TheAdventuresOfTintin1991 Professor Cuthbert Calculus]] and [[WesternAnimation/MissSpidersSunnyPatchFriends Betty Beetle]]. Her friends are [[WesternAnimation/{{Sixteen}} Starr]], [[Series/RadioFreeRoscoe Ray Brennan]], [[WesternAnimation/{{Franklin}} Rabbit]], and [[Series/WindAtMyBack Maisey McGinty]]; and their teacher is [[WesternAnimation/CareBears1980s Love-a-Lot Bear]]
* ''WesternAnimation/AquaTeenHungerForce'': [[WesternAnimation/OKKOLetsBeHeroes Doctor Grayman]], [[WesternAnimation/TheBrakShow Thundercleese]], and [[CreatorCameo the shows creator]] all share a house in New Jersey. The narrator of ''WesternAnimation/{{Squidbillies}}'' is their neighbor and [[WesternAnimation/SpaceGhostCoastToCoast Zorak]] is a mad scientist.
* ''WesternAnimation/{{Arcane}}'': [[VideoGame/{{Titanfall}} Kuben Blisk]] takes in two orphaned sisters, [[WesternAnimation/SpiderManSpiderVerse Gwen Stacy]], and a little girl who grows up to be [[Film/MissPeregrinesHomeForPeculiarChildren Emma Bloom]]. Gwen and Emma are raised alongside [[Franchise/Ben10 Ben Tennyson]] and Franchise/SonicTheHedgehog. After a disastrous chain of events that lead to [[spoiler:Emma accidentally killing Ben and Sonic as well as Blisk dying]], the two sisters have a falling out. [[VideoGame/FalloutNewVegas Vulpes Inculta]], Blisk's [[CainAndAbel "brother"-turned-enemy]], takes in Emma as his adoptive daughter while Gwen gets abducted and imprisoned. [[{{Timeskip}} Years later]], Gwen is released by [[Film/HarryPotter Cho Chang]] and comes back home with her to find Emma, who unbeknownst to either of them, has become Vulpes' minion and is far from the sister she once knew.
* ''WesternAnimation/{{Archer}}'': [[WesternAnimation/HomeMovies Coach McGuirk]] is a secret agent working alongside [[WesternAnimation/DextersLaboratory Dee Dee]] for an organization run by his mother, [[Series/{{Dinosaurs}} Fran Sinclair]]. His coworkers include [[WesternAnimation/BoJackHorseman Sextina Aquafina]] (who is also his on again, off again girlfriend), [[WesternAnimation/RickAndMorty Jerry Smith]], [[WesternAnimation/AskTheStorybots Beep]], [[WesternAnimation/FriskyDingo Valerie, Xtacle]], and [[WesternAnimation/SeaLab2021 Dr. Virjay]].
* ''WesternAnimation/AroundTheWorldInEightyDays'': [[WesternAnimation/TheBatman Alfred Pennyworth]] wants to marry [[WesternAnimation/TheJetsons Judy Jetson]], the niece to an unscrupulous aristocrat named [[Theatre/TheMerchantOfVenice Shylock]] who wagers that if Alfred can go [[TitleDrop around the world in eighty days]], he can marry Judy.
* ''WesternAnimation/{{Arthur}}'': [[Series/RadioActive Ethan St. John]] ([[WesternAnimation/TheSaveUms Noodle]] in Seasons 6-11; [[WesternAnimation/BabarAndTheAdventuresOfBadou Badou]] in Seasons 12-19) lives in Elwood City with his parents [[WesternAnimation/Patrol03 Shorty and Carmen]], his younger sister [[ComicStrip/LittleLulu Annie Inch]] ([[WesternAnimation/MonaTheVampire George]] in Seasons 4-6; [[WesternAnimation/PopPixie Fixit]] in Seasons 11-15, WesternAnimation/MikeTheKnight in Seasons 16-17; [[WesternAnimation/PawPatrol Alex]] in Seasons 20-21; [[WesternAnimation/TopWing Rod]] in Seasons 22-25) [[note]]Jason Swzimmer and Andrew Dayton, DW's voice actors in Seasons 7-10 and Seasons 18-19 respectively, have no other known credits[[/note]], and pet dog [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Goddard]]. He attends Lakewood Elementary with his friends, who include [[WesternAnimation/WhatsWithAndy Danny Pickett]], [[Series/AreYouAfraidOfTheDark Kiki]], [[WesternAnimation/CampLakebottom Gretchen]], and [[VideoGame/DeusExHumanRevolution William Taggart]]. Their teacher is [[VideoGame/SplinterCell President David Bowers]] and the principal is WesternAnimation/{{Papa Beaver|sStorytime}}.
* ''WesternAnimation/AsToldByGinger'': [[VideoGame/Spyro2RiptosRage Elora the Faun]] is an ordinary junior high school student who, with her friends [[Anime/CannonBusters Philly the Kid]], [[WesternAnimation/TheWildThornberrys Pippo]], and [[WesternAnimation/ConstantPayne Amanda Payne]], tries to become popular amongst the school's students. [[WesternAnimation/SpiderManTheAnimatedSeries Deborah Whitman]], the resident popular girl, takes a liking to Elora and tries to include her in whatever plans she has, but Deborah's accomplice [[WesternAnimation/{{Rugrats}} Susie Carmichael]] does not like Elora. Meanwhile, Elora's little brother [[WesternAnimation/TheSuperMarioBrosSuperShow Princess Toadstool]] and his best friend [[WesternAnimation/{{Animaniacs}} Dot Warner]] get into their own shenanigans and Elora's mother [[WesternAnimation/TurboFAST Queen Invicta]] often gives her advice. Deborah's younger brother is [[WesternAnimation/DextersLaboratory Agent Honeydew]].
* ''WesternAnimation/AtomicBetty'': [[WesternAnimation/TheBerenstainBears Sister Bear]] lives a secret double life defending the galaxy under the command of [[WesternAnimation/RubyGloom Poe]]. She and her crew, [[WesternAnimation/AtomicPuppet Professor Tite-Gripp]] and [[Series/PuppetsWhoKill Rocko the Dog]], fight Supreme Evil Overlord [[WesternAnimation/TheLegendOfZelda1989 King Harkinian]] and his sidekick [[WesternAnimation/TheRaccoons Bert Raccoon]] (later [[WesternAnimation/SevenLittleMonsters Three]]). Her parents are [[WesternAnimation/{{Cyberchase}} Motherboard]] and [[WesternAnimation/ScaredySquirrel Nestor]]; her friends are [[WesternAnimation/TimothyGoesToSchool Fritz]] and [[WesternAnimation/{{Franklin}} Beaver]]; and [[WesternAnimation/XMenTheAnimatedSeries Jean Grey]] is the AlphaBitch, whose brother [[WesternAnimation/CampLakebottom McGee]] is Sister Bear's love interest.
* ''WesternAnimation/AtomicPuppet'': [[WesternAnimation/ElTigre White Pantera]] is transformed into a sock puppet by his disgruntled sidekick [[WesternAnimation/TotalDrama Cody]] and teams up with [[WesternAnimation/LooneyTunesCartoons Daffy Duck]], who can put him on his hand to become a superhero. The duo fight villains such as [[WesternAnimation/AtomicBetty Sparky]], [[WesternAnimation/NumbChucks Hooves]], and [[WesternAnimation/RubyGloom Skull Boy]]. Daffy's best friend is [[WesternAnimation/TheMysteriesOfAlfredHedgehog Cynthia]] and his family is made of [[WesternAnimation/HeroElementary Mr. Sparks]], [[WesternAnimation/MissSpidersSunnyPatchFriends Spindella]], and [[Anime/{{Bakugan}} Julie Makimoto]]. [[Anime/SailorMoon Kenji Tsukino]] is the local newsman.
* ''WesternAnimation/AvatarTheLastAirbender'': After being frozen for 100 years, [[WesternAnimation/TheBackyardigans Pablo]] (as well as his pets [[VideoGame/GearsOfWar General RAAM]] and [[WesternAnimation/SpongeBobSquarePants Cannonball Jenkins]]) is woken by a young waterbender named [[WesternAnimation/AmericanDragonJakeLong Rose]] and her brother [[Series/OneHundredThingsToDoBeforeHighSchool Jack Roberts]]. Together, along with [[WesternAnimation/MeetTheRobinsons Young Franny]], they journey around the world while being pursued by [[Film/{{Hook}} Rufio]] and his uncle [[WesternAnimation/SamuraiJack Aku]]. After taking care of other villains such as Rufio's rival [[VideoGame/TheWorldEndsWithYou Daisukenojo "Beat" Bito]], [[Franchise/HarryPotter Lucius Malfoy]] and EvilChancellor [[WesternAnimation/YoungJustice2010 King Faraday]], everyone must defeat Rufio's manipulative sister [[Franchise/ScoobyDoo Daphne Blake]] and their EvilOverlord father [[Franchise/StarWars Luke Skywalker]].
** ''WesternAnimation/TheLegendOfKorra'': [[Series/{{Entourage}} Amy Miller]], the reincarnation of Pablo, is taught airbending by [[Film/SpiderManTrilogy J. Jonah Jameson]], the son of Pablo and Rose. [[Series/MarriedWithChildren Bud Bundy]] and [[Film/HorribleBosses Kenny Sommerfeld]] are two brothers who are her friends; [[Film/TheLastAirbender Princess Yue]] is the {{TheTeam|Normal}} BadassNormal, while [[WesternAnimation/TransformersPrime Starscream]] and [[WesternAnimation/TransformersAnimated Lockdown]] are working to rid the world of bending. Meanwhile, an old threat of [[spoiler:bloodbender]] [[Franchise/DCAnimatedUniverse Lex Luthor]] returns in the form of [[WesternAnimation/StarWarsTheCloneWars Captain Rex]]. [[Series/{{Lost}} Jin-Soo Kwon]], [[Series/MadMen Sally Draper]], and [[Film/AustinPowers Frau Farbissima]] are also involved. Pablo, Jack, Rose, and Franny's future selves are [[WesternAnimation/{{Dinosaur}} Aladar]], [[WesternAnimation/BackAtTheBarnyard Otis]], [[Film/NorthByNorthwest Eve Kendall]] and [[Manga/{{Naruto}} Sakura Haruno]] respectively.
** In the second season, Amy must stop her uncle, [[Series/SonsOfAnarchy Officer Craft]], from releasing the ancient spirit of chaos [[WesternAnimation/GreenLanternTheAnimatedSeries Atrocitus]] from his prison. Meanwhile, [[WesternAnimation/HarveyBirdmanAttorneyAtLaw Mentok the Mindtaker]] attempts to profit off a civil war, and it's revealed that 10,000 years ago, the Avatar was created when [[Series/TheWalkingDead Glen]] fused with [[VideoGame/ValkyriaChronicles Selvaria Bles]] to defeat Atrocitus.
** In the third season, a spiritual event gives random nonbenders--among them Jonah's brother [[Film/OfficeSpace Tom Smykowski]] and Franny's granddaughter (via Farbissima's half-sister [[WesternAnimation/AdventureTime Cherry Cream Soda Gal]]) [[VideoGame/KingdomHearts358DaysOver2 Xion]]--airbending. Unfortunately, one of the ''other'' parties affected is the BadassNormal [[BombThrowingAnarchists anarchist]] [[WesternAnimation/AdventureTime Bob Rainicorn]]...and he proceeds to break out of jail, spring his ColdSniper girlfriend [[WesternAnimation/TransformersRobotsInDisguise Windblade]] and their friends MagmaMan [[VideoGame/DawnOfWar Azariah Kyras]] and DisabledBadass BloodKnight [[WesternAnimation/TUFFPuppy Kitty Katswell]] from their tailored cells, and go gunning for Amy. [[spoiler:And their sleeper agent [[WesternAnimation/{{Futurama}} Kif Kroker]] was already in Cherry's city...]]
** In the final season, Amy is recuperating from the events of the previous with the help of Rose/Eve [[spoiler:and later Franny/Sakura, who's become [[Anime/DigimonAdventure Mimi Tachikawa]] in her old age]]. Meanwhile, [[WesternAnimation/TeenageMutantNinjaTurtles2012 Mona Lisa]]--aided by Kenny, Mentok, [[Manga/KOn Yui Hirasawa]] and [[Manga/SgtFrog Keroro]]--starts a war; and Jin resurfaces to apologize to Yue for having wronged her [[spoiler:before getting killed by Mona Lisa's giant mecha]]. When all is said and done, [[WesternAnimation/BlazeAndTheMonsterMachines Stripes]] [[spoiler:has abdicated the throne of the Earth Kingdom to pursue a career as a singer]], and [[spoiler:Amy hooks up with Yue]] at Mentok and Yui's wedding reception.
* ''WesternAnimation/AvengersAssemble'': Patriotic SuperSoldier [[VideoGame/ResidentEvil5 Chris Redfield]], the armor-clad [[Series/{{Heroes}} Nathan Petrelli]][[TheOtherDarrin /]][[WesternAnimation/KungFuPandaLegendsOfAwesomeness Po]] (whose armor is supported by the A.I. [[WesternAnimation/TransformersPrime Hardshell]]), God of Thunder [[Manga/FullmetalAlchemist Roy Mustang]], the savage [[VideoGame/BatmanArkhamCity Solomon Grundy]], archer [[VideoGame/DeadOrAlive Ryu Hayabusa]], spy [[Anime/BlueGender Marlene Angel]], and the winged [[WesternAnimation/Ben10Omniverse Rook Blonko]] are a team of superheroes. Among the villains are Chris' archenemy [[VideoGame/TransformersWarForCybertron Air Raid]], the cybernetically-enhanced [[WesternAnimation/LoonaticsUnleashed Optimatus]], Asgardian troll [[WesternAnimation/YoungJustice2010 Martian Manhunter]], ruler of Latveria [[WesternAnimation/CodenameKidsNextDoor Father]], the vampire [[WesternAnimation/TheSecretSaturdays V.V. Argost]], and corrupt businessman [[WesternAnimation/GreenLanternTheAnimatedSeries Razer]].
** Season 2: It's revealed that Air Raid is working with [[VideoGame/StreetFighterIV Sagat]]. Among other villains are the robotic [[ComicBook/DCTheNewFrontier Slam Bradley]] and a super villain group consisting of [[VideoGame/BatmanArkhamOrigins Black Mask]], [[WesternAnimation/BewareTheBatman Batman]], [[VideoGame/DeadOrAlive Christie]], [[WesternAnimation/YoungJustice2010 Kid Flash]], [[WesternAnimation/OzzyAndDrix Osmosis Jones]], and WesternAnimation/SamuraiJack. In the season finale, Sagat returns with a [[TheVoiceless silent brute]], [[Anime/LuckyStar Yukata Kobayakawa, Kagami Hiiragi]], [[WesternAnimation/XMenEvolution Professor Charles Xavier]], and [[WesternAnimation/SuperFriends Desaad]] working for him.
* ''WesternAnimation/TheAvengersEarthsMightiestHeroes'': [[Anime/CrayonShinChan Hiro Nohara]], [[VideoGame/DragonAgeOrigins the Arishok]], [[Franchise/MassEffect Saren Arterius]] (the personification of [[Series/{{Revenge}} Nolan Ross]]'s anger), [[VideoGame/BatmanArkhamSeries the Riddler]], and [[Anime/DigimonAdventure Sora Takenouchi]] form a team of superheroes. They're soon joined by [[WesternAnimation/GIJoeRenegades Zartan]], [[VideoGame/MetalGearSolid Sigint]], and [[WesternAnimation/JusticeLeagueUnlimited Captain Atom]] in Season 1 and [[VideoGame/KnightsOfTheOldRepublic Bastila]] and [[Franchise/MassEffect Sovereign]] in Season 2. Among their enemies are [[VideoGame/Uncharted2AmongThieves Zoran Lazarevic]], [[VideoGame/NoMoreHeroes Travis Touchdown]], [[Literature/{{Durarara}} Celty Sturluson]], [[WesternAnimation/Ben10 Diamondhead]], [[WesternAnimation/TransformersPrime Ratchet]], [[WesternAnimation/JusticeLeagueCrisisOnTwoEarths Martian Manhunter]], [[WesternAnimation/TheGarfieldShow Jon Arbuckle]], [[Franchise/AlienVsPredator Carl Bishop Weyland]], and [[VideoGame/MetalGearSolid2SonsOfLiberty Vamp]]. [[Series/{{Becker}} Jake Malinack]] and [[Series/{{Sliders}} Maggie Beckett]] are part of a government agency that sometimes works with the team.
** Season 2 welcomes the Fantastic Four, composed of [[WesternAnimation/StarWarsTheCloneWars Captain Rex]], [[VideoGame/BatmanArkhamAsylum Bane]], [[WesternAnimation/SupermanTheAnimatedSeries Jimmy Olsen]], and [[VideoGame/GodOfWar Athena]], as well as more heroes, including [[WesternAnimation/JusticeLeagueDoom Cyborg]], [[Series/TheJamieFoxxShow Braxton P. Hartnabrig]], [[WesternAnimation/BatmanTheAnimatedSeries Dick Grayson]], [[Anime/WolfsRain Tsume]], [[VideoGame/SonicTheHedgehog2006 Princess Elise]], [[Anime/TengenToppaGurrenLagann Leeron Littner]], [[Series/{{Fringe}} Phillip Broyles]], [[Series/DrakeAndJosh Drake Parker]] ([[TheOtherMarty who was once]] [[WesternAnimation/GreenLanternTheAnimatedSeries the Green Lantern]]), [[VideoGame/FinalFantasyXIII Yaag Rosch]], and [[Anime/CowboyBebop Spike Spiegel]]. Among the new villains are [[WesternAnimation/TheBatman Metallo]], [[WesternAnimation/{{Rugrats}} Tommy Pickles]], [[WesternAnimation/{{CatDog}} Eddie the Squirrel]], [[VideoGame/BatmanArkhamCity Clayface]], [[WesternAnimation/MortalKombatDefendersOfTheRealm Shang Tsung]], [[VideoGame/StarCraftII Zeratul]], [[VideoGame/StreetFighterIV Ryu]], [[Series/StarTrekTheNextGeneration Data]], [[WesternAnimation/BeastWars Megatron]], [[WesternAnimation/GeneratorRex Van Kleiss]] (who is pursued by a team of heroes consisting of [[Franchise/{{Halo}} Master Chief]], [[WesternAnimation/TeenTitans2003 Malchior]], [[VideoGame/BatmanArkhamCity Two-Face]], [[Literature/BludgeoningAngelDokuroChan Zansu]], and [[WesternAnimation/MyLifeAsATeenageRobot Brit Crust]]), [[Film/TransformersDarkOfTheMoon Laserbeak]], and [[Film/Underworld2003 Raze]].
* ''WesternAnimation/TheAvengersUnitedTheyStand'': [[WesternAnimation/RescueHeroes Jack Hammer]], Anime/SailorMoon, [[Anime/BakutenShootBeyblade Boris Balkov]], [[WesternAnimation/XMenTheAnimatedSeries Morph]], [[Series/KungFu1972 Lulu Morgan]], [[WesternAnimation/InspectorGadget2015 Dr. Claw]], [[Anime/OutlawStar Aisha Clanclan]], and [[Series/RadioFreeRoscoe Principal Waller]] are a team of superheroes.
!!B
* ''Literature/{{Babar}}'': [[Series/TheRedGreenShow Hap Shaughnessy]] rules a kingdom of elephants with his wife [[WesternAnimation/CadillacsAndDinosaurs Governor Scharnhorst]], his brother-in-law [[WesternAnimation/FlyingRhinoJuniorHigh Buford]], and his children [[Series/ThePolitician Ricardo]], [[Series/ReadyOrNot1993 Mona]], [[WesternAnimation/TheMagicSchoolBus Ralphie Tennelli]], and [[WesternAnimation/TimothyGoesToSchool Yoko]]. He was tutored by [[WesternAnimation/{{Beetlejuice}} Delia Deetz]] and [[Film/SawV Bernie]] is his closest friend. His advisors are [[Series/FridayThe13thTheSeries Jack Marshak]] and [[WesternAnimation/MaggieAndTheFerociousBeast The Ferocious Beast]], while [[WesternAnimation/TheRaccoons George Raccoon]] is his chef. [[WesternAnimation/{{Rupert}} Constable Growler]] and [[WesternAnimation/BeverlyHillsTeens Nikki Darling]] rule a rival kingdom of rhinos with their son [[Series/KungFuTheLegendContinues Chuckie]] and their advisor [[WesternAnimation/BlazingDragons Sir Burnevere]]. Governor Scharnhorst was [[WesternAnimation/TeenTitans2003 Raven]] as a child.
** (2000 revival): Hap Shaughnessy and Governor Scharnhorst are now [[WesternAnimation/{{Mysticons}} Nova Terron]] and [[WesternAnimation/JacobTwoTwo Florence]], while their first three kids are now [[WesternAnimation/{{Franklin}} Franklin, Snail, and Rabbit]]. They now travel the world via hot-air balloon and have magical adventures in different lands alongside Bernie (who is now [[WesternAnimation/{{Cyberchase}} the second Buzz]]).
** ''WesternAnimation/BabarAndTheAdventuresOfBadou'': The adventures of Hap's grandson [[WesternAnimation/{{Arthur}} Arthur Read]] (son of Ricardo, who is now [[WesternAnimation/LittleBear Rusty Bear]]), whose circle of friends includes Bernie's daughter [[WesternAnimation/DNAce Sloane Plunderman]], as well as WesternAnimation/{{Max|AndRuby}}, [[WesternAnimation/JaneAndTheDragon Princess Lavinia]], and [[WesternAnimation/{{Stoked}} George Ridgemount]]. Their teacher is [[WesternAnimation/RoliePolieOlie Polina Polie]]. Also, [[WesternAnimation/DonkeyKongCountry King K. Rool]] is the scheming ambassador of a kingdom of crocodiles whose nephews are [[WesternAnimation/{{Grojband}} Corey Riffin and Kin Kujira]], while [[WesternAnimation/TotalDrama Trent]] rules the savannah. Constable Growler and Nikki Darling are now [[WesternAnimation/AtomicBetty Admiral DeGill]] and [[WesternAnimation/{{Wayside}} Miss Mush]], and their grandson [[Anime/{{Medabots}} Ikki Tenryou]] is Arthur's rival.
* ''WesternAnimation/BabyLooneyTunes'': [[WesternAnimation/EdEddNEddy Double D]], [[Manga/CardcaptorSakura Julian]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Party Favor, Igneous Rock]], [[WesternAnimation/SittingDucks Bill]], [[WesternAnimation/StrawberryShortcake Blueberry Muffin]], Anime/{{Hamtaro}}, and [[Manga/{{Inuyasha}} Kagura]] are baby versions of the ''WesternAnimation/LooneyTunes'', cared for by [[WesternAnimation/SpiderManAndHisAmazingFriends Aunt May]] and her nephew [[Anime/DragonBallZ Vegeta]].
* ''WesternAnimation/BackAtTheBarnyard'': [[WesternAnimation/SanjayAndCraig Craig]], [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Sheen Estevez]], [[VideoGame/MetalGearSolid Liquid Snake]], [[WesternAnimation/BubbleGuppies Mr. Grouper]], [[WesternAnimation/DannyPhantom the Box Ghost]], [[Series/GoodLuckCharlie Amy Duncan]], [[Series/TheNewAdventuresOfOldChristine Barb Baran]], and [[WesternAnimation/HeyArnold Ernie Potts]] are a group of farm animals who go on adventures when their master, [[VideoGame/TransformersWarForCybertron Ratchet]] isn't looking. [[Film/KungPowEnterTheFist The Chosen One]] and [[WesternAnimation/WordGirl Mrs. Botsford]] are their neighbors.
* ''WesternAnimation/BackToTheFuture'': [[WesternAnimation/DannyPhantom Danny Fenton]] goes on adventures in time with [[WesternAnimation/TheSimpsons Homer Simpson]], Homer's wife [[Film/{{Elf}} Emily Hobbs]] and Homer's sons [[WesternAnimation/TheSpectacularSpiderMan Peter Parker]] and [[Series/LeaveItToBeaver Kevin Cleaver]]; Danny's girlfriend [[WesternAnimation/ThePowerpuffGirls Blossom]] sometimes travels with them too. [[WesternAnimation/BatmanTheAnimatedSeries Tony Zucco]] and his various ancestors often cause trouble for Danny and Homer. In live action segments at the end of the show, Homer, now [[Film/StarTrekIIITheSearchForSpock Commander Kruge]], is assisted by Series/BillNyeTheScienceGuy.
* ''WesternAnimation/BadDog'': The misadventures of an obsessively obedient dog owned by WesternAnimation/GeorgeShrinks, whose older siblings are [[WesternAnimation/TotalDrama Courtney]] and [[VideoGame/MegaManLegends Teisel Bonne]], parents are [[WesternAnimation/TheAdventuresOfSamAndMaxFreelancePolice Sam]] and [[Series/LittleMosqueOnThePrairie Sarah Hamoudi]], and grandfather is [[WesternAnimation/{{Babar}} Basil]].
* ''WesternAnimation/TheBagelAndBeckyShow'': [[WesternAnimation/InvaderZIM Almighty Tallest Purple]] and [[WesternAnimation/{{Mysticons}} Oozie Q]] are siblings who have adventures in the town of Awkward Hills with their friend, [[WesternAnimation/ThreeAmigonauts Burt]]. [[WesternAnimation/RoliePolieOlie Bonita Bevel]] is their mother.
* ''WesternAnimation/TheBatman'': [[Anime/SailorMoon Tuxedo Mask]] is a masked vigilante who, with the help of his sidekicks [[Manga/{{Naruto}} Tenten]] and [[Film/RaisingHelen Oliver Portman]], fights villains such as [[WesternAnimation/DannyPhantom Skulker]], [[WesternAnimation/RockosModernLife Heffer Wolfe]], [[VideoGame/GodOfWar Hades]], [[Anime/AfroSamurai Justice]], [[Franchise/ANightmareOnElmStreet Freddy Krueger]], [[WesternAnimation/TeenTitans2003 Blackfire]], [[Film/GhostbustersII Janos Poha]], [[WesternAnimation/AGoofyMovie Max Goof]], [[WesternAnimation/TheSimpsons Homer Simpson]], and [[Film/MortalKombatAnnihilation Lord Raiden]]. [[VideoGame/LegacyOfKain Mortanius]] is Tuxedo Mask's butler and Tenten's police commissioner father is [[Series/TheXFiles Agent Skinner]]. Other cops include [[Series/BattlestarGalactica2003 William Adama]] / [[WesternAnimation/{{Gargoyles}} Jade]], [[Series/ThePractice Eugene Young]], and WesternAnimation/{{Mulan}}.
* ''WesternAnimation/BatmanTheBraveAndTheBold'': [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Hoss Delgado]], along with other superheroes like [[WesternAnimation/TheSpectacularSpiderMan Harry Osborn]], [[WesternAnimation/ThunderCats2011 Lion-O]], [[WesternAnimation/TheFairlyOddParents Cupid]], [[Film/FullMetalJacket Gunnery Sergeant Hartman]], and [[VideoGame/FinalFantasyXII Gilgamesh]], fight off villains like [[WesternAnimation/Ben10AlienForce Azmuth]], [[VideoGame/GodOfWar Hermes]], [[WesternAnimation/TeenTitans2003 Control Freak]], and [[WesternAnimation/CodenameKidsNextDoor Numbuh 86]]. In the end, [[Series/HappyDays Arthur 'Fonzie' Fonzarelli]] tries to save the show from getting cancelled.
** One episode has Hoss facing off against the [[TheMusicMeister hypnotic powers]] of [[Series/HowIMetYourMother Barney Stintson]].
** [[Franchise/ScoobyDoo A movie]] involves Hoss teaming up with [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Goddard]], [[Film/Scream1996 Stuart Macher]], [[WesternAnimation/HiHiPuffyAmiYumi Yumi Yoshimura]], [[Series/TheFactsOfLife Natalie]], and [[Franchise/{{Transformers}} Megatron]].
** In the advertisement for the tie-in game, he, along with [[Franchise/RatchetAndClank Ratchet]], take some time off to play video games at the insistence of [[Creator/PaulReubens Pee-wee Herman]].
* ''WesternAnimation/BeastWars'': The heroic Maximals [[WesternAnimation/RollBots Lance]], [[Anime/DragonBallZ Captain Ginyu]], & WesternAnimation/{{Mega Man|RubySpears}}, led by [[WesternAnimation/MegaManRubySpears Guts Man]], battle the evil [[WesternAnimation/TransformersAnimated Optimus Prime]] and his Predacon forces, composed of [[Anime/DragonBallZ Mr. Satan, Oolong]], [[Anime/UnicronTrilogy Tidal Wave]], and [[WesternAnimation/MegaManRubySpears Eddie]], who is the TheChewToy. [[WesternAnimation/XMenEvolution Wolverine]] pulls a HeelFaceTurn and becomes VitriolicBestBuds with Lance. [[Anime/SaberMarionetteJ Tiger]] also switches sides to be with [[Manga/BlackLagoon Verrocchio]]. [[Series/{{Supernatural}} Dr. Jennings]], [[Manga/MaisonIkkoku Yukari Godai]], and [[VideoGame/CallOfDuty Lt. Vasquez]] later join the Maximals, while [[Series/{{Sanctuary}} Helen Magnus' dad]], [[Anime/MegaManNTWarrior Count Zap]], and [[Series/BattlestarGalactica2003 The First Hybrid]] join the Predacons.
** ''WesternAnimation/BeastMachines'': Immediately following the events on Earth, Guts Man, Mega Man, Lance, and Tiger return to their home planet only to discover that Optimus Prime has taken it over with his henchmen, [[Toys/{{Bionicle}} Matau]] ([[spoiler:in actuality, Verrocchio]]), [[VideoGame/DawnOfWar Gabriel Angelos]] ([[spoiler:Ginyu]]) and [[Series/{{Highlander}} Joe Dawson]] ([[spoiler:Eddie]]). Now, with the help of [[WesternAnimation/XMenEvolution Gambit]] and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Queen Chrysalis]], they must bring balance to the planet and stop the Vehicons. [[WesternAnimation/WarPlanets Graveheart]] and [[Manga/BlackLagoon Balalaika]] later join up with Optimus after the "departures" of Matau and Gabriel.
* ''WesternAnimation/BeatBugs'': [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rainbow Dash]], [[WesternAnimation/{{Dinotrux}} Albert]], [[WesternAnimation/LittlestPetShopAWorldOfOurOwn Edie Von Keet]], [[Series/TheGoodDoctor Marcie Murphy]], and [[WesternAnimation/KidVSKat Coop Burtonburger]] are five young bug friends who learn valuable life lessons through covers of songs by Music/TheBeatles. Recurring characters include [[Anime/DragonBallZ Vegeta]], [[WesternAnimation/BarbieInAChristmasCarol the Spirit of Christmas Future]], [[WesternAnimation/EdEddNEddy Rolf, Jonny 2x4]], [[Film/TheSantaClause2 a seismic interpreter]], [[WesternAnimation/{{Ninjago}} Acronix]], [[Manga/BlackLagoon Revy]], [[WesternAnimation/SabrinaTheAnimatedSeries Uncle Quigley]], [[Manga/DeathNote Misa Amane]], and [[WesternAnimation/JohnnyTest Mary Test]].
* ''WesternAnimation/BeavisAndButtHead'': [[WesternAnimation/KingOfTheHill Hank Hill]] and [[WesternAnimation/SouthParkBiggerLongerAndUncut Kenny McCormick]] are two idiotic teens who like to watch music videos and snark on them when they're not making mischief.
* ''WesternAnimation/BeethovenTheAnimatedSeries'': [[Series/MadMen Freddy Rumsen]] is a friendly St. Bernard who drives his owners [[WesternAnimation/SupermanTheAnimatedSeries Sam Lane]] and [[WesternAnimation/DannyPhantom Maddie Fenton]] crazy and goes on adventures with his friends [[Film/BadBoys1995 Captain Howard]], [[WesternAnimation/TinyToonAdventures Babs Bunny]], and [[WesternAnimation/SpongeBobSquarePants Patrick Star]]. The family also includes Sam and Maddie's children [[Series/TheNanny Maggie Sheffield]], [[WesternAnimation/TheSwanPrincess Derek]], and [[WesternAnimation/HeyArnold Helga Pataki]] as well as their pet hamster [[WesternAnimation/AvatarTheLastAirbender Guru Pathik]].
* ''WesternAnimation/{{Beetlejuice}}'': [[VideoGame/ResidentEvil Claire Redfield]] is a PerkyGoth that hangs out with the ghostly [[WesternAnimation/XMenTheAnimatedSeries Angel]]. Claire's parents are [[Series/MurdochMysteries Mr. Todd]] and [[WesternAnimation/LittleBear Hen]], while Angel's neighbors are [[WesternAnimation/CareBears1980s Professor Coldheart]], [[WesternAnimation/{{Babar}} Movie!Rataxes]], and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rarity]]. Angel's vehicle is [[WesternAnimation/StickinAround Mr. Lederhosen]] (who sometimes transforms into [[WesternAnimation/{{Rupert}} The Professor]]), his parents are [[WesternAnimation/TheRaccoons Bert and Melissa Raccoon]], and his goody-two-shoes younger brother is [[WesternAnimation/MissSpidersSunnyPatchFriends Felix the Frog]]. [[WesternAnimation/BatmanTheAnimatedSeries Batgirl]] is the AlphaBitch.
* ''WesternAnimation/BeingIan'': [[WesternAnimation/{{Dinotrux}} Revvit]] is a young boy with aspirations of filmmaking. His family is made up of his parents, [[Anime/PowerpuffGirlsZ Professor Utonium]] and [[Anime/DragonBallZ Android 19]], and his older brothers, [[WesternAnimation/ClassOfTheTitans Herry]] and [[WesternAnimation/EdEddNEddy Ed]]. His best friends are [[WesternAnimation/HotWheelsWorldRace Nolo Passaro]] and [[WesternAnimation/JimmyTwoShoes Heloise]]; his respective paternal and maternal grandmothers are [[WesternAnimation/PollyPocket Griselle Grande]] and [[WesternAnimation/ChipAndPotato Grandma Pug]]; and [[WesternAnimation/AdventuresOfSonicTheHedgehog Coconuts]] is a FunnyForeigner who works at Professor Utonium's piano store. The show was created by [[Manga/DragonBall Goku]].
* ''WesternAnimation/Ben10'': [[WesternAnimation/TheFairlyOddParents Timmy Turner]] finds an alien artifact that can turn him into numerous aliens (such as [[WesternAnimation/AvatarTheLastAirbender Appa]], [[VideoGame/RatchetAndClank Captain Qwark]], [[Anime/TheBigO Roger Smith]], [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Eight-Armed Willy]], [[WesternAnimation/SquirrelBoy Rodney J. Squirrel]], [[WesternAnimation/DannyPhantom Fright Knight]], and [[WesternAnimation/MonstersVsAliens General W.R. Monger]]). With the help of his cousin [[WesternAnimation/AllGrownUp Rachel]] and his grandpa [[VideoGame/MetalGearSolid Colonel Roy Campbell]], he squares off against people like [[WesternAnimation/TheAvengersEarthsMightiestHeroes Red Skull]], [[VideoGame/MetalGearSolid3SnakeEater Ivan Raidenovitch Raikov]] ([[Anime/DigimonFrontier Takuya Kanbara]] in his first appearance), [[WesternAnimation/YoungJustice2010 Aqualad]] and his niece [[Anime/SamuraiChamploo Fuu]], and [[VideoGame/XMenLegends Beast]].
** ''WesternAnimation/Ben10AlienForce'': Timmy has matured into [[Manga/{{Naruto}} Sasuke Uchiha]], Rachel has also matured into [[VideoGame/TheLastOfUs Ellie]], Raikov has had a HeelFaceTurn and matured into [[WesternAnimation/SuperRobotMonkeyTeamHyperforceGo Chiro]], and they've teamed-up against the forces of evil. This time, the bad guys include [[Series/StarTrekTheNextGeneration Wesley Crusher]], [[WesternAnimation/AvatarTheLastAirbender Bato]], and Red Skull (now [[Film/TransformersDarkOfTheMoon Sideswipe]]). Sideswipe has [[WesternAnimation/AmericanDad Klaus]] as a minion. Many of Sasuke's aliens now sound exclusively like Appa, while one sounds like [[WesternAnimation/UltimateSpiderMan2012 the Wrecker]] and another has two personalities, one of whom is [[Film/Godzilla1998 Elsie Chapman]] and the other one is WesternAnimation/{{Batman|TheAnimatedSeries}}.
** ''WesternAnimation/Ben10UltimateAlien'': [[WesternAnimation/CaptainPlanetAndThePlaneteers Ma-Ti]] reveals Sasuke's identity to the public, making him into a celebrity to children and a villain to adults. Sasuke has to overcome this to save the world from [[WesternAnimation/BatmanTheBraveAndTheBold Aquaman]]. Later, Sasuke has to deal with [[WesternAnimation/TeenageMutantNinjaTurtles1987 Splinter]] and [[WesternAnimation/BatmanUnderTheRedHood the Joker]]. The alien with two additional personalities briefly reappear, and this time Elsie is [[WesternAnimation/IceAge Roshan]] while Batman is [[WesternAnimation/{{Gargoyles}} Brooklyn]].
** ''WesternAnimation/Ben10Omniverse'': After Ellie and Chiro leave for college, Sasuke teams up with a rookie alien named [[WesternAnimation/TransformersAnimated Bumblebee]], and they now have to fight [[WesternAnimation/XMenEvolution Professor Charles Xavier]], who turns out to be working for [[VideoGame/BatmanArkhamCity Hugo Strange]] and [[WesternAnimation/TheLooneyTunesShow Marvin the Martian]]. Later on, Sasuke and Bumblebee deal with the return of [[WesternAnimation/TeenageMutantNinjaTurtles2012 Shredder]] and his daughter [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]]. Also, Sideswipe is back to sounding like the Red Skull. Other villains include Klaus's gang (consisting of [[WesternAnimation/TheTransformers Perceptor]], [[WesternAnimation/TheSpectacularSpiderMan Sandman]], and [[WesternAnimation/GIJoeARealAmericanHero the Baroness]]) [[Series/ParksAndRecreation Tom Haverford]], [[Film/TheBreakfastClub John Bender]], [[WesternAnimation/BeastWars Megatron]], [[WesternAnimation/GIJoeResolute Storm Shadow]], and [[Franchise/StarWars Luke Skywalker]]. Many of Sasuke's aliens sound like [[WesternAnimation/AvengersAssemble the Falcon]], [[WesternAnimation/LegionOfSuperHeroes Superman]], [[Manga/InuYasha Sesshomaru]], [[WesternAnimation/SpiderManTheAnimatedSeries Hydro-Man]], and [[WesternAnimation/{{Chowder}} Schnitzel]], with the alien with two personalities now sounding like [[WesternAnimation/StevenUniverse Jasper]] and [[WesternAnimation/TransformersRobotsInDisguise2015 Drift]]. The show is intercut with adventures of Sasuke back when he was Timmy.
* ''WesternAnimation/BenAndHollysLittleKingdom'': Within the miniscule Little Kingdom, there live two types of beings: elves and fairies. [[Film/CrookedHouse Eustace]] the elf is best friends with [[WesternAnimation/PeppaPig Zoë Zebra]] the fairy princess, and regularly go on adventures together. Zoë lives in the Little Castle with her parents, [[Series/{{Pennyworth}} Arthur Pennyworth]] and [[Film/FourWeddingsAndAFuneral Laura]], as well as their housemaker [[WesternAnimation/PeppaPig Miss Rabbit]]. Eustace lives in the Great Elf Tree with his parents WesternAnimation/FiremanSam and [[Series/TheBrittasEmpire Julie Porter]], while [[Series/{{Thunderbirds}} Gordon Tracy]] lives at the top and oversees the elves' duties. [[Series/TheSarahJaneAdventures Mr Smith]] is a caricature of Boris Johnson.
* ''WesternAnimation/BensCity'': [[Anime/SamuraiPizzaCats Speedy Cerviche]] is literally everybody.
* ''Literature/TheBerenstainBears'':
** (1985 series) [[WesternAnimation/TwoStupidDogs Mr. Hollywood]] is married to [[WesternAnimation/LinusTheLionhearted Granny Goodwitch]] and has two kids, [[WesternAnimation/RainbowBrite Krys]] and [[WesternAnimation/APupNamedScoobyDoo Velma Dinkley]]. [[WesternAnimation/CodenameKidsNextDoor Professor XXXL]] is the mayor of the town they live in.
** (2003 series) [[WesternAnimation/DonkeyKongCountry King K. Rool]] is married to [[Series/DueSouth Meg Thatcher]] and has two kids, [[Film/{{Juno}} Paulie Bleeker]] and WesternAnimation/AtomicBetty.
* ''WesternAnimation/BestEd'': [[WesternAnimation/{{Detentionaire}} Principal General Barrage]] and [[WesternAnimation/{{Spliced}} Two-Legs Joe]] are best friends who live in the town of Swellville.
* ''WesternAnimation/BewareTheBatman'': [[Series/ThirdWatch Carlos Nieto]] fights crime with his butler [[Manga/{{Hellsing}} Enrico Maxwell]] and swordswoman [[WesternAnimation/TransformersPrime Arcee]]. [[Series/That70sShow Red Forman]] is a cop who has to learn to trust Carlos. Among the villains they have to deal with are [[WesternAnimation/TheAvengersEarthsMightiestHeroes Falcon]], [[WesternAnimation/DannyPhantom Sam Manson]], [[WesternAnimation/BatmanTheBraveAndTheBold Ocean Master]], and [[WesternAnimation/AvatarTheLastAirbender Guru Pathik]] and his sidekick [[Film/{{Blade}} Dragonetti]]. [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]] is Red's daughter and is a fangirl of Carlos and Arcee.
* ''WesternAnimation/BigCityGreens'': [[CreatorCameo One of the show's creators]] is a country boy who lives in the big city with his sister WesternAnimation/{{Pearlie}}, his dad [[WesternAnimation/TheJungleBook2 Bagheera]], and his grandmother [[Series/ItsAlwaysSunnyInPhiladelphia Artemis Dubois]]. His friends are a nerdy rich kid named [[WesternAnimation/YoungJustice2010 Cyborg]] and a coffee barista named [[WebVideo/RileyRewind Riley Brown]]. His mother, [[Film/{{Bridesmaids}} Rita]], was recently released from prison.
* ''WesternAnimation/BigGuyAndRustyTheBoyRobot'': [[WesternAnimation/KingOfTheHill Bobby Hill]] is the title Boy Robot, who goes on adventures with the Big Guy, who's piloted by [[UsefulNotes/ToysRUs Geoffrey the Giraffe]]. [[Series/BeverlyHills90210 Andrea Zuckerman]], [[WesternAnimation/TeenTitans2003 Val-Yor]], and [[Series/TheDrewCareyShow Mimi]] back them up. Other supporting cast include [[WesternAnimation/KingOfTheHill Bill Dauterive]], [[WesternAnimation/AvatarTheLastAirbender Lion Turtle]], [[Film/TheRockyHorrorPictureShow Dr. Frank N. Furter]] and [[Film/FullMetalJacket Gunnery Sergeant Hartman]]. This show turned out to have an AllStarCast.
* ''WesternAnimation/{{Birdz}}'': [[WesternAnimation/RockAndRule Angel]] is the daughter of [[Anime/SailorMoon Kenji Tsukino]] and [[VideoGame/ResidentEvil Ada Wong]], while her sisters are WesternAnimation/{{Yin|YangYo}} and [[WesternAnimation/XMenTheAnimatedSeries Storm]]. She attends school with [[WesternAnimation/{{Franklin}} Badger]], [[WesternAnimation/BeverlyHillsTeens Tara Belle]], [[WesternAnimation/TotalDrama Justin]], [[WesternAnimation/{{Rupert}} Rupert Bear]], and [[Anime/SamuraiPizzaCats Speedy Cerviche]]; their teacher is [[WesternAnimation/PippiLongstocking Ms. Prysselius]], and the principal is [[WesternAnimation/{{Dinosaucers}} Allo]]. [[WesternAnimation/{{Babar}} Cornelius]] is the local police officer while [[WesternAnimation/TheZhuZhus Mr. Squiggles]] is a patient of Kenji.
* ''WesternAnimation/BlastersUniverse'': [[WesternAnimation/GetEd Mr. Simon Bedlam]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Gilda the Griffon]], and [[WesternAnimation/{{Fangbone}} Venomous Drool]] travel across the galaxy to stop intergalactic villains from destroying their home planet of Omega.
* ''WesternAnimation/BlazeAndTheMonsterMachines'': [[VideoGame/{{Uncharted}} Nathan Drake]] is a super fast monster truck driven by [[WesternAnimation/TheLionGuard Beshte]] (later [[WesternAnimation/TheLoudHouse Clyde]], [[WesternAnimation/TheEpicTalesOfCaptainUnderpants George Beard]], [[WesternAnimation/SpideyAndHisAmazingFriends Miles Morales/Spin]], and [[Series/DramaClub2021 Skip]]). Together, they go on adventures around the city and learn about science. They are accompanied by the mechanic [[WesternAnimation/BubbleGuppies Deema]] (later [[Series/AndiMack Iris]] and [[WesternAnimation/{{Firebuds}} Wiley Riley]]), the tiger truck [[VideoGame/FalloutNewVegas Muggy]], the cowgirl [[Manga/{{Naruto}} Sakura]], the daredevil [[WesternAnimation/TeenTitans2003 Control Freak]], and the dinosaur truck [[WesternAnimation/{{Amphibia}} One-Eyed Wally]]. They run afoul of a cheating monster truck named [[WesternAnimation/YoungJustice2010 Martian Manhunter]], and his perky assistant [[WesternAnimation/{{Disenchantment}} Elfo]], though Manhunter becomes nicer overtime and a friend to Nathan. Later on, Nathan and the others are joined by [[WesternAnimation/{{TOTS}} Ava]].
* ''WesternAnimation/BlazingDragons'': [[WesternAnimation/AngelaAnaconda Gordy Rhinehart]] is a squire for the Knights of the Square Table, comprised of lazy buffoon [[Series/KungFuTheLegendContinues Kermit Griffin]] (later [[WesternAnimation/BlastersUniverse M.E.L.]]), CampGay [[WesternAnimation/{{Redwall}} Basil Stag Hare]], veteran Scot [[WesternAnimation/CareBears1980s Beastly]], large and imposing [[Anime/MetalFightBeyblade Dr. Ziggurat]], and small but gassy [[WesternAnimation/InspectorGadget Chief Quimby]]. Princess [[Anime/SailorMoon Sailor Venus]], the daughter of [[WesternAnimation/DonkeyKongCountry Cranky Kong]] and step-daughter of [[Film/CaesarAndCleopatra2009 Brittanus]], is Gordy's crush. The BigBad is [[Series/FrankieDrakeMysteries Dr. Peter Thomson]] (later [[WesternAnimation/XMenTheAnimatedSeries Professor X]]), whose henchmen are evil knights [[WesternAnimation/TheAdventuresOfTeddyRuxpin Tweeg]] (later [[WesternAnimation/{{Anastasia}} Czar Nicholas II]]), [[Anime/{{Bakugan}} Naga]], and [[WesternAnimation/{{Dinosaucers}} Genghis Rex]], and sorceress [[Series/{{Heartland}} Maggie Duval]]. [[Series/FXTheSeries Captain Marvin Van Duran]] and [[Series/{{Debra}} Principal Ridge]] is the two-headed jester while [[WesternAnimation/{{Birdz}} Mr. Nuthatch]] provides commentary on the characters' adventures.
* ''WesternAnimation/BlessTheHarts'': [[Film/{{Bridesmaids}} Annie Walker]] lives in Greenpoint, North Carolina with her mother [[Film/{{Idiocracy}} Rita]] and her daughter [[Series/{{Workaholics}} Jillian Belk]]. Her boyfriend is [[Film/Neighbors2014 Jimmy Blevins]].
* ''WesternAnimation/BobAndMargaret'': [[WesternAnimation/PeppaPig Dr. Elephant]] (later [[WesternAnimation/AvatarTheLastAirbender Guru Pathik]]) and the show's creator are a married couple living in London. Dr. Elephant/Guru Pathik's Canadian cousins are [[WesternAnimation/MissSpidersSunnyPatchFriends Mr. Mantis]] and [[WesternAnimation/JoJosCircus Ms. Kersplatski]], and his brother [[Film/NightAtTheMuseum Octavius]] is a TV chef. Dr. Elephant/Guru Pathik and the show's creator later move to Toronto where their neighbors are [[WesternAnimation/JacobTwoTwo Principal I.M. Greedyguts]] and [[WesternAnimation/MarvinTheTapDancingHorse Edna]] (later [[WesternAnimation/ScaredySquirrel Nestor's Momma]]).
* ''WesternAnimation/BobbysWorld'': [[WesternAnimation/MuppetBabies1984 Baby Animal]] is a very imaginative little boy. His parents are [[Film/{{Gremlins}} Gizmo]] and [[WesternAnimation/TinyToonAdventures Shirley the Loon]]. His obnoxious siblings are [[WesternAnimation/BaltoIIIWingsOfChange Dusty]] and [[WesternAnimation/JonnyQuestVersusTheCyberInsects Jonny Quest]] (who would later become [[WesternAnimation/KingOfTheHill Bobby Hill]]). Plus there's Aunt [[WesternAnimation/DarkwingDuck Binkie Muddlefoot]] and Uncle [[WesternAnimation/{{Barnyard}} Pig]]. Baby Animal is also best friends with [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Jimmy Neutron]].
* ''WesternAnimation/BobsBurgers'': [[WesternAnimation/{{Archer}} Sterling Archer]] runs a greasy burger shop. Along for the ride is his wife [[Series/LateNight Jimmy's Mom]], awkward teenage daughter [[WesternAnimation/AdventureTime T.V.]], weird son [[Series/{{Delocated}} Evgeni Mirminski]], and sociopath [[WesternAnimation/GravityFalls Mabel Pines]].
* ''WesternAnimation/BobTheBuilder'': (UK; 1999) [[Series/MenBehavingBadly Tony Smart]] is a construction worker who, along with his business partner [[WesternAnimation/TheSecretShow Anita Knight]], complete construction and reparation projects with their team of anthropomorphic construction vehicles, consisting of [[Series/WaterlooRoad Eddie Lawson]], [[WesternAnimation/ThomasAndFriends James]], [[WesternAnimation/ChopSockyChooks Chuckie Chan]], [[WesternAnimation/LavenderCastle Lyca]] and [[Literature/SoulMusic Mort]].
** (UK; 2015) Tony and Anita (now [[Film/HarryPotter Stan Shunpike]] and [[Series/DowntonAbbey Anna Bates]]) move to a new location, and are joined by [[Film/BadBoysForLife Armando]]. Their machines are now WesternAnimation/FiremanSam, [[Series/TheInbetweeners Neil Sutherland]], [[WesternAnimation/TheOctonauts Peso]], [[Series/Miranda2009 Stevie Sutton]] and [[WesternAnimation/MattHatterChronicles Gomez]].
** (US; 1999) [[Franchise/{{Patlabor}} Kataoka]] (later [[Series/TrueJacksonVP Max Madigan]], then [[WesternAnimation/FifiAndTheFlowertots Bumble]]) is a construction worker who, along with his business partner [[WesternAnimation/{{Fantomcat}} Tabs Wildcat]], complete construction and reparation projects with their team of anthropomorphic construction vehicles, consisting of [[WesternAnimation/GerryAndersonsNewCaptainScarlet Destiny Angel]] (later WesternAnimation/HorridHenry)[[note]]Sonya Leite, Lofty's first actress, has no other notable acting credits[[/note]], [[WesternAnimation/{{Ninjago}} Dareth]] (later [[WesternAnimation/ThunderbirdsAreGo Virgil Tracy]]), [[Series/DoctorWho Trinity Wells (later Ace]]), [[WesternAnimation/RoaryTheRacingCar Roary]] and [[VideoGame/ProfessorLayton Luke Triton]].
** (US; 2015) Bumble and Tabs (now [[WesternAnimation/BeastWars Quickstrike]] and Anna Bates) move to a new location, and are joined by [[WesternAnimation/IronManArmoredAdventures War Machine]]. Their machines are now [[WesternAnimation/MyLittlePonyFriendshipIsMagic Snails, Sweetie Belle]], Neil Sutherland, [[WesternAnimation/{{Ninjago}} Kai]] and [[Anime/DragonBallZ Goku]], who have been joined by [[WesternAnimation/ThreeTwoOnePenguins Fidgel]] and [[WesternAnimation/StreetFighter M. Bison]].
* ''WesternAnimation/BoJackHorseman'': [[Series/ArrestedDevelopment Gob Bluth]] is the washed-up star of the sitcom ''Horsin' Around''. His agent/on-and-off girlfriend is [[WesternAnimation/ShrekTheThird Cinderella]], and his rommate is [[Series/BreakingBad Jesse Pinkman]]. His former rival in television was [[Film/ThereWillBeBlood Prescott]], while [[Series/{{Community}} Annie Edison]] is ghostwriting is autobiography.
* ''WesternAnimation/BoltsAndBlip'': [[WesternAnimation/TotalDramaPresentsTheRidonculousRace Don]] and [[Series/RookieBlue Officer Duncan Moore]] are two robots who participate in fighting tournaments alongside [[WesternAnimation/{{Arthur}} Muffy Crosswire]], their coach [[VideoGame/FarCry5 Eli Palmer]], and his assistant WesternAnimation/IggyArbuckle. [[Series/MonsterWarriors Dink Dorman]] is their rival, while the tournament announcers are [[WesternAnimation/JimmyTwoShoes Samy Garvin and General Molotov]]. The BigBad is [[WesternAnimation/AtomicBetty Maximus I.Q.]], the former colleague of [[WesternAnimation/SevenLittleMonsters Three]], the scientist who created all the robots.
* ''WesternAnimation/{{Bonkers}}'': [[WesternAnimation/TaleSpin Don Karnage]] loses his job as Wackytoon Studios' biggest cartoon star and becomes a cop. He is first partnered with [[WesternAnimation/TheLooneyTunesShow Taz]], and then later with [[WesternAnimation/BatmanTheAnimatedSeries Cassidy]].
* ''WesternAnimation/TheBoondocks'': [[Series/{{Southland}} Detective Lydia Adams]] and [[Series/TwentyFour Sandra Palmer]] are two brothers raised in the suburbs by [[Series/TheWayansBros John 'Pops' Williams]]. [[Series/Reno911 Deputy S. Jones]] is a lawyer who married [[WesternAnimation/SpongeBobSquarePants Karen]]. [[WesternAnimation/StrokerAndHoop Coroner Rick]] is a white supremacist. [[Series/TheMaryTylerMooreShow Lou Grant]] is a CorruptCorporateExecutive whose grandson, [[Series/ChappellesShow Buc Nasty]], is a [[PrettyFlyForAWhiteGuy wigger]] who spends most of his time robbing stores with his partner [[Film/PulpFiction Jules Winnfield]].
* ''WesternAnimation/TheBotsMaster'': [[Anime/MobileSuitGundamWing Heero Yuy]] leads a brigade of heroic robots against an evil MegaCorp led by [[Anime/DragonBallZ Cell]] and his subordinates [[WesternAnimation/BeastWars Cheetor]] and [[WesternAnimation/EdEddNEddy Sarah]]. The robots working for Heero include the likes of [[WesternAnimation/ReBoot Mike the TV]], [[Franchise/DragonBall Krillin]], and [[WesternAnimation/EdEddNEddy Double D]].
* ''WesternAnimation/BoyGirlDogCatMouseCheese'': [[WesternAnimation/TheFungies Nevin]],[[Anime/YuGiOhZexal Rio Kastle]], [[Anime/PokemonTheSeries Mantle]], [[TheVoiceless a cat]], [[WesternANimation/WinxClub Orlando]], and [[VideoGame/SonicRush Blaze the Cat]] have all become stepsiblings and must learn to get along.
* ''WesternAnimation/{{Braceface}}'': [[Film/{{Clueless}} Cher Horowitz]] (later [[WesternAnimation/{{Sixteen}} Nikki Wong]]) is a teenage girl with braces that effect her ordinary life in strange ways. Her friends are [[WesternAnimation/JoJosCircus Peaches]] and [[WesternAnimation/MyFriendRabbit Rabbit]], and [[Anime/SailorMoon Tuxedo Mask]] is her crush, whose best friend is [[WesternAnimation/TheMagicSchoolBus Carlos]]. [[WesternAnimation/TotallySpies Alex]] is the AlphaBitch whose sidekick is [[WesternAnimation/AnneOfGreenGablesTheAnimatedSeries Diana Barry]]. Cher/Nikki's mother is [[WesternAnimation/XMenTheAnimatedSeries Mystique]], and her brothers are [[WesternAnimation/TotalDrama Geoff]] and Film/{{Scott Pilgrim|VsTheWorld}}.
* ''WesternAnimation/BrandyAndMrWhiskers'': [[Series/TheBigBangTheory Penny]] is a pampered poodle whose life changes when she ends up stuck in the Amazon with [[WesternAnimation/AaahhRealMonsters Ickis]]. The two get into many shenanigans together in their new home, and make friends with such creatures as [[WesternAnimation/TransformersAnimated Starscream]], [[VideoGame/ScarfaceTheWorldIsYours Tony Montana]], [[WesternAnimation/BatmanTheAnimatedSeries Batgirl]], [[WesternAnimation/WelcomeToTheWayne Ansi Molina]], [[VideoGame/MassEffect Female Commander Shepard]], and [[WesternAnimation/MadagascarEscape2Africa Florrie the Lion]].
* ''Franchise/{{Bratz}}'': Series/PunkyBrewster, one of the twins from ''Series/SisterSister'', [[WesternAnimation/AvatarTheLastAirbender Ty Lee]], and [[WesternAnimation/TheFairlyOddParents Trixie Tang]] run a fashion magazine and do stuff, usually against antagonists [[Series/TheBigBangTheory Penny]] and [[WesternAnimation/TheWildThornberrys Eliza Thornberry]], who both work for [[Series/JustShootMe Nina Van Horn]]. [[Videogame/FinalFantasyX2 Buddy]], WesternAnimation/KickButtowski, and [[WesternAnimation/TheEmperorsNewSchool Malina]] are supporting characters.
* ''WesternAnimation/{{Breadwinners}}'': [[WesternAnimation/OKKOLetsBeHeroes Raymond]] and [[WesternAnimation/{{Unikitty}} Master Frown]] are ducks who work for a bread-delivering company. [[WesternAnimation/TeenTitans2003 Control Freak]] is the ducks' pet frog, [[WesternAnimation/AskTheStorybots Bang]] is a legendary creature who lives in the bread mines, [[WesternAnimation/TheFairlyOddParents Chloe Carmichael]] is a mechanic that they occasionally seek advice from, [[VideoGame/KidIcarusUprising Hades]] is their best customer, and [[VideoGame/{{Skylanders}} Stealth Elf]] is a police officer who dislikes them.
* ''WesternAnimation/{{Brickleberry}}'': [[WesternAnimation/KingOfTheHill Buckley]] works at a national park run by WesternAnimation/SpongeBobSquarePants. His co-workers include [[Series/LuckyLouie Walter]], [[CreatorCameo the show's creator]], and [[Series/ItsAlwaysSunnyInPhiladelphia Dee]] (later [[WesternAnimation/UglyAmericans Callie]]). Creator/DanielTosh is a talking bear.
* ''WesternAnimation/TheBrothersFlub'': [[WesternAnimation/TeenTitans2003 Robin]] and [[Film/{{Godspell}} Jerry]] are brothers who work for a delivery company run by [[Series/GirlMeetsWorld Grammy Hart]].
* ''WesternAnimation/{{Bubsy}}'': Obnoxious bobcat [[WesternAnimation/{{Animaniacs}} Dr. Otto Scratchensniff]] volunteers to test a virtual reality helmet invented by [[WesternAnimation/WildWestCOWBoysOfMooMesa Marshall Moo Montana]]. They are accompanied by Otto's pet armadillo [[WesternAnimation/RainbowBrite Lurky Dismal]], his niece and nephew [[WesternAnimation/ScoobyDooAndTheAlienInvaders Velma Dinkley]] and [[WesternAnimation/{{Futurama}} Tinny Tim]], and Marshall Moo's assistant [[WesternAnimation/VeggietalesInTheHouse Junior Asparagus]]. [[WesternAnimation/ScoobyDooAndTheReluctantWerewolf Repulsa]] sends her henchmen [[WesternAnimation/KungFuPandaLegendsOfAwesomeness Constable Hu]] and [[WesternAnimation/BumpInTheNight Mr. Bumpy]] to steal the helmet for herself.
* ''WesternAnimation/BumpInTheNight'': WesternAnimation/{{Cat|Dog}} is a small green monster who lives under the bed of a 10-year-old boy with his best friend [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Principal Willabee]]. Other characters include [[WesternAnimation/ThePowerpuffGirls Grubber]], [[Anime/LoveLive Cocoa Yazawa]], [[WesternAnimation/TomAndJerryTheMovie Robyn Starling]], [[WesternAnimation/FindingNemo Bloat]], and [[WesternAnimation/{{Rugrats}} Tommy Pickles]].
* ''WesternAnimation/ButtUglyMartians'': [[WesternAnimation/PetAlien Tommy Cadle]], [[WesternAnimation/DocMcStuffins Chilly the Snowman]], and [[WesternAnimation/{{Catscratch}} Gordon]] are a team of crime-fighting martians who regularly foil the evil plans of their leader [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius King Goobot]]. Joining them are [[WesternAnimation/DextersLaboratory Dexter's Mom]], [[WesternAnimation/{{Animaniacs}} Yakko Warner]], [[WesternAnimation/TheLifeAndTimesOfJuniperLee Ray-Ray]], and [[WesternAnimation/UltimateSpiderMan2012 Miles Morales]], while [[Series/TheUntouchables Eliot Ness]] is a martian hunter sent to exterminate them.
* ''WesternAnimation/BuzzLightyearOfStarCommand'': [[WesternAnimation/TheEmperorsNewGroove Kronk]] dons a spacesuit and sets out to save the universe. Joining him are [[WesternAnimation/CloneHigh Joan of Arc]], [[WesternAnimation/RoadRovers Sport]], and [[Series/{{Scrubs}} The Janitor]] (sometimes [[Film/PrettyWoman Mr. Hollister]]). They defend the galaxy from the likes of {{WesternAnimation/Batman|TheBraveAndTheBold}}, [[WesternAnimation/ToyStory2 Al]], [[WesternAnimation/{{Freakazoid}} Roddy MacStew]], [[WesternAnimation/{{Hercules}} Pain]], and [[WesternAnimation/TheHunchbackOfNotreDameDisney Judge Claude Frollo]]. In the pilot movie, Kronk was [[Series/HomeImprovement Tim "the Toolman" Taylor]].
* ''WesternAnimation/TheBuzzOnMaggie'': [[WesternAnimation/TheLoudHouse Lucy Loud]] is a preteen housefly whose parents are [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Captain K'nuckles]] and [[WesternAnimation/PepperAnn Aunt Janie Diggety]]. Her siblings are [[WesternAnimation/BackToTheFuture Marty McFly]], [[WesternAnimation/{{Gargoyles}} Lexington]], and [[WesternAnimation/TeenTitans2003 Raven]]. Her best friend at school is [[WesternAnimation/MyLifeAsATeenageRobot Tiff Crust]] while her rival is [[VideoGame/BatmanArkhamCity Harley Quinn]].
!!C
* ''WesternAnimation/CadillacsAndDinosaurs'': In a post-apocalyptic future where dinosaurs once again rule the Earth, mechanic [[Series/FXTheSeries Rick Forsythe]] and ambassador [[Anime/SailorMoon Sailor Jupiter]] struggle against a variety of foes, notably a power-hungry council composed of [[WesternAnimation/{{Babar}} Queen Celeste]], [[WesternAnimation/{{Cyberchase}} Motherboard]], and [[WesternAnimation/RoliePolieOlie Baxter Bevel]].
* ''WesternAnimation/{{Caillou}}'': [[WesternAnimation/{{Franklin}} Harriet Turtle]] (later [[Series/FifteenLove Megan O'Connor]] and then [[WesternAnimation/DragonHunters Zaza]]) explores their world and has vivid imagination sequences.
** (puppet segments): [[WesternAnimation/TheAdventuresOfTeddyRuxpin The Wooly What's-It,]] [[Series/UnderTheUmbrellaTree Iggy Iguana]], [[Series/TheNoddyShop Rusty the Tin Clown and Warloworth Q. Weasel]] discover the world around them.
* ''WesternAnimation/CampLakebottom'': [[Anime/{{Bakugan}} Dan Kuso]], WesternAnimation/PippiLongstocking, and [[WesternAnimation/{{Sixteen}} Darth Mall]] attend a creepy summer camp run by [[WesternAnimation/JohnCallahansQuads Blazer]], [[WesternAnimation/RoliePolieOlie Percy Polie]], and [[WesternAnimation/YinYangYo Eradicus]]. Their archenemies are rich kid [[WesternAnimation/TotalDrama Noah]] and Dan's sister [[WesternAnimation/AnneOfGreenGablesTheAnimatedSeries Anne Shirley]].
* ''WesternAnimation/CampLazlo'': [[WesternAnimation/TheFairlyOddParents Mr. Crocker]] is a fun-loving boy scout at a summer camp run by [[WesternAnimation/TheBatman the Penguin]] and [[WesternAnimation/TeenTitans2003 Mumbo]]. Other people at the camp are [[WesternAnimation/DextersLaboratory Dexter's dad]], [[WesternAnimation/ElTigre Puma Loco]], [[WesternAnimation/SpongebobSquarepants Larry the Lobster]], [[WesternAnimation/TheLandBeforeTime Petrie]], [[WesternAnimation/TheMarvelousMisadventuresOfFlapjack Dr. Barber, Lolly Poopdeck]], [[WesternAnimation/RockosModernLife Filburt]], [[WebAnimation/MightyMagiswords Ralphio]], [[WesternAnimation/AdventureTime Peppermint Butler, Duke of Nut]], [[WesternAnimation/SecretMountainFortAwesome Slog]], [[WesternAnimation/RegularShow Spacey McSpacetree]], [[WesternAnimation/CodenameKidsNextDoor Mr. Boss]], and [[WesternAnimation/SamuraiJack Scaramouche]]. [[WesternAnimation/CatDog Lube]] is the camp cook, while [[WesternAnimation/SpongebobSquarepants Plankton]] is the nurse. WesternAnimation/JohnnyBravo and [[WesternAnimation/TheLifeAndTimesOfJuniperLee Monroe]] appear as lifeguards in one episode. [[WesternAnimation/ToyStory2 Barbie]], who attends the girls' camp, has a crush on Crocker while The Penguin sports one on [[WesternAnimation/TheLittleMermaid1989 Ariel]], the head of the girls' camp, which is also attended by [[WesternAnimation/SpongebobSquarepants Karen]], [[WesternAnimation/TheLoudHouse Rita Loud]], [[WesternAnimation/BaltoIIWolfQuest Jenna]], [[WesternAnimation/IceAge Roshan]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight Sparkle]], and [[VideoGame/TheWonderful101 Wonder-Pink]]. Ariel's assistant is [[WesternAnimation/TheBoondocks Sarah Dubois]]. Barbie turns out to be the daughter of the Penguin's boss [[WesternAnimation/ThePowerpuffGirls Grubber]]. Larry's older brothers are WesternAnimation/SpongeBobSquarePants, [[WesternAnimation/FostersHomeForImaginaryFriends Eduardo]], [[WesternAnimation/ClassOf3000 Principal Luna]], and [[WesternAnimation/PenguinsOfMadagascar Kowalski]]. [[spoiler:In the final episode, it turns out that the Penguin impersonated the real Scoutmaster [[WesternAnimation/MyGymPartnersAMonkey Jake Spidermonkey]].]]
* ''WesternAnimation/CaptainCavemanAndTheTeenAngels'': WesternAnimation/DaffyDuck is a prehistoric superhero who solves mysteries with [[Series/TheFreshPrinceOfBelAir Viola "Vy" Smith]], [[WesternAnimation/ScoobyDooAndTheGhoulSchool Winnie Werewolf]], and [[WesternAnimation/MyLittlePonyTheMovie1986 Sweet Stuff]].
* ''WesternAnimation/CaptainFlamingo'': [[WesternAnimation/MyLittlePonyPonyLife Spike]] is a kid superhero who helps other children solve their problems with the help of his best friend sidekick [[WesternAnimation/DiGataDefenders Maia]]. Other characters include over-protective only child [[WesternAnimation/PeepAndTheBigWideWorld Peep]], smart and sophisticated [[WesternAnimation/MyFriendRabbit Coral]], disaster-making [[WesternAnimation/OddJobJack Bobby Lee]], Spike's cousin nemesis [[WesternAnimation/RoliePolieOlie Olie]], Maia's rival [[WesternAnimation/{{Cyberchase}} Inez]], smart and constantly freaking out [[WesternAnimation/MissSpidersSunnyPatchFriends Shimmer]], easily distracted [[WesternAnimation/{{Braceface}} Sharon Spitz]], wacky genius [[WesternAnimation/XMenTheAnimatedSeries Jean Grey]], sweet girl [[Series/NaturallySadie J.P.]] (later [[WesternAnimation/CareBearsBigWishMovie Wish Bear]]), Spike's baby brother [[WesternAnimation/MyBigBigFriend Yuri]], and Spike's mom and dad are [[WesternAnimation/JoJosCircus Dr. Seltzer]] and [[WesternAnimation/BlazingDragons Cinder]]. [[WesternAnimation/RubyGloom Scaredy Bat]] is the show's narrator.
* ''WesternAnimation/CaptainNTheGameMaster'': WesternAnimation/{{Ed|EddNEddy}} is thrust into the video game world, where he becomes the personal protector of Princess [[WesternAnimation/MyLittlePonyTales Patch]]. With the assistance of [[Anime/MobileSuitGundamSeed Patrick Zala]], [[Manga/DragonBall Oolong]], [[Manga/DeathNote L Lawliet]], and later [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Goddard]], Ed fights the evil forces of [[Manga/RanmaOneHalf Ryoga Hibiki]], [[WesternAnimation/AdventuresOfSonicTheHedgehog Grounder]], [[WesternAnimation/BabyLooneyTunes the Tasmanian Devil]], and [[Film/LittleShopOfHorrors Audrey II]].
* ''WesternAnimation/CaptainPlanetAndThePlaneteers'': Our world is in peril. [[Series/StarTrekTheNextGeneration Guinan]]/ [[Film/SupermanFilmSeries Lois Lane]], the spirit of Earth, can no longer stand the terrible destruction plaguing our planet. She gives five special rings to five special young people. From Africa, [[Series/Roots1977 Kunta Kinte]] with the power of earth. From North America, [[WesternAnimation/CartoonAllStarsToTheRescue The Drug Dealer]] with the power of fire. From the Soviet Union/Eastern Europe, [[WesternAnimation/{{Rugrats}} Lil Deville]] with the power of wind. From Asia, [[WesternAnimation/MyLifeAsATeenageRobot Jenny "XJ-9" Wakeman]] with the power of water. And from South America, [[WesternAnimation/TeenTitans2003 Robin]] with the power of heart. With the five powers combined they summon earth's greatest champion - [[WesternAnimation/PolePosition DANIEL DARRET]]! In addition, the villains include [[WesternAnimation/MonstersInc Henry Waternoose]] / [[WesternAnimation/TaleSpin Baloo]], [[Franchise/JurassicPark Ian Malcolm]] / [[WesternAnimation/PinkyAndTheBrain The Brain]], [[Series/TheWestWing President Bartlet]] / [[WesternAnimation/ChalkZone Skrawl]], [[Film/WhenHarryMetSally Sally]] / [[WesternAnimation/SouthPark Liane Cartman]], and [[Film/TheRockyHorrorPictureShow Frank N. Furter]].
* ''Franchise/CareBears''
** ''WesternAnimation/CareBears1980s'': WesternAnimation/{{Rudolph|TheRedNosedReindeer1964}} (later [[WesternAnimation/TheDevilAndDanielMouse Daniel Mouse]]), [[WesternAnimation/{{Wayside}} Miss Mush]], [[WesternAnimation/StickinAround Ms. Mobley]], [[WesternAnimation/WildKratts Donita Donata]], [[WesternAnimation/{{Ewoks}} Shodu Warrick]], [[WesternAnimation/TheRaccoons Ralph Raccoon]], [[WesternAnimation/KidVsKat Old Lady Munson]], [[WesternAnimation/InspectorGadget Chief Quimby]], [[WesternAnimation/LittleBear Mother Bear]], [[WesternAnimation/RoliePolieOlie Bonita Bevel]], and [[WesternAnimation/LetsGoLuna Lucie Hopper]] are colorful bears from the land of Care-a-lot who help childen in need of caring while also foiling the evil plans of [[WesternAnimation/DonkeyKongCountry Krusha]] and later [[WesternAnimation/{{Dinosaucers}} Dimetro]] and his henchmen [[WesternAnimation/{{Redwall}} Cap'n Clogg]] and [[WesternAnimation/FlyingRhinoJuniorHigh Lydia Lopez]].
** ''WesternAnimation/CareBearsWelcomeToCareALot'': [[Manga/{{Naruto}} Jiraiya]], [[VideoGame/FinalFantasyVIII Squall]] [[VideoGame/DissidiaFinalFantasy Leonhart]], [[Manga/{{Bleach}} Nnoitra]], [[Manga/GirlsBravo Kirie Kojima]], [[VideoGame/BinaryDomain Rachel Townsend]], [[WesternAnimation/PeterRabbit Lily Bobtail]], and [[VideoGame/MortalKombatVsDCUniverse Catwoman]] are a bunch of colorful bears who teach lessons and morals to kids.
** ''WesternAnimation/CareBearsAndCousins'': [[Manga/MobileSuitGundamTheOrigin Denim]], [[WesternAnimation/HeyArnold Rhonda Wellington Lloyd]], [[WesternAnimation/BuddyThunderstruck Handsome Joe]], and [[Anime/YourName Taki Tachibana]] reunite with the bears.
* ''WesternAnimation/CarlSquared'': [[WesternAnimation/TheMagicSchoolBus Ralphie Tennelli]] orders a clone of himself named [[WesternAnimation/XMenTheAnimatedSeries Proteus]] to do stuff for him. His best friend [[Film/CampRock Barron James]] is the only one who knows of this clone. His girlfriend is [[WesternAnimation/AngelaAnaconda Gina Lash]], and his family includes his sister [[WesternAnimation/RubyGloom Misery]], his mother [[WesternAnimation/{{Wayside}} Mrs. Jewls]], and his dad [[Series/ThisIsWonderland Cameron Tiernay]].
* ''WesternAnimation/CarmenSandiego'': [[Series/JaneTheVirgin Jane Villanueva]] is an orphan raised by the heads of a global crime syndicate (including [[Anime/{{Naruto}} Gaara]], [[WesternAnimation/StevenUniverse Dr. Maheswaran]], [[WesternAnimation/Ducktales2017 Mrs. Beakley]], and [[VideoGame/{{Overwatch}} Hanzo]]) who has wanted to be a thief her whole life. However, she abandons the syndicate after seeing what lengths they'll go to to secure priceless artifacts, and, with help from young hacker [[Series/StrangerThings Mike Wheeler]], dedicates her life to taking them down. Along the way, she fights former classmates [[Franchise/Ben10 Charmcaster]], [[WesternAnimation/LooneyTunesCartoons Bugs Bunny]], and [[Series/OrangeIsTheNewBlack Brook Soso]], and is pursued by a French Interpol agent and his partner [[VideoGame/{{Overwatch}} D.Va]].
* ''WesternAnimation/Castlevania2017'': The vampire hunter [[Film/TheHobbit Thorin Oakenshield]], the witch [[WesternAnimation/WinxClub Flora]] and the Dhampir [[WesternAnimation/RickAndMorty Pat Gutterman]] are working together to fight the vampire [[VideoGame/DantesInferno Dante]] after he goes to a war against humanity following his wife's death.
* ''WesternAnimation/TheCatInTheHatKnowsALotAboutThat'': [[Film/ThreeAmigos Ned Nederlander]] teaches [[WesternAnimation/TotalDramaPresentsTheRidonculousRace Junior]] and [[WesternAnimation/TopWing Shelly]] about the world. They are joined by Junior and Shelly's goldfish [[WesternAnimation/TheZhuZhus Chunk]] and Ned's helpers [[WesternAnimation/AlmostNakedAnimals Howie]] and [[WesternAnimation/{{Cyberchase}} Delete]].
* ''WesternAnimation/CatDog'': [[WesternAnimation/OKKOLetsBeHeroes Lord Boxman]] and WesternAnimation/SpongeBobSquarePants (alternatively, [[WesternAnimation/TheSuperHeroSquadShow Thanos and Iron Man]]) are conjoined brothers. Recurring antagonists include [[{{WesternAnimation/Futurama}} Phillip J. Fry]], [[WesternAnimation/{{Chowder}} Mung Daal]], [[WesternAnimation/TheLooneyTunesShow Elmer Fudd]], and a gang made up of [[WesternAnimation/RockosModernLife Rocko, Heffer,]] and [[WesternAnimation/HarveyBeaks Grada]]. [[WesternAnimation/MikeLuAndOg Mike Mazinsky]], [[WesternAnimation/TheRenAndStimpyShow Stimpy]], [[VideoGame/TakAndThePowerOfJuju Jibolba]], and [[Series/TalesFromTheCrypt the Crypt Keeper]] are friends of theirs and [[WesternAnimation/CampLazlo Clam]] is their roommate. [[spoiler: [[WesternAnimation/OpenSeason Giselle]] and [[Anime/PrincessMonoke Jiko]] are Boxman and [=SpongeBob=]'s parents.]]
* ''WesternAnimation/{{Catscratch}}'': [[WesternAnimation/HouseOfMouse Jose Carioca]], [[Series/{{Seinfeld}} Newman]], and [[WesternAnimation/InvaderZim Almighty Tallest Purple]] live in a mansion with their DeadpanSnarker butler [[WesternAnimation/TheCritic Orson Welles]]. Jose has a crush on his neighbor [[WesternAnimation/{{Chowder}} Panini]], and [[Anime/TengenToppaGurrenLagann Nia Teppelin]] becomes a SixthRanger later on.
* ''WesternAnimation/{{Centaurworld}}'': In the middle of a war, [[WesternAnimation/SpiderManSpiderVerse Peni Parker]] gets separated from her best friend [[Theatre/{{Carousel}} Carrie Pipperidge]] and winds up in a fantastical world where each and every organism is a centaur. There, Peni partners up with the centaur equivalents of [[WesternAnimation/SofiaTheFirst Princess Prisma]], [[Series/HowIMetYourMother Ted Mosby]], [[WesternAnimation/TransformersRescueBots Blades]], [[WesternAnimation/TheWonderfulWorldOfMickeyMouse Mickey Mouse]], and... uh... [[DescendedCreator somebody pretty important,]] and embarks on a quest to get back home to Carrie, singing songs with her new friends along the way and learning the value of self-care and healing from trauma, but Peni eventually has to prevent a terrifying creature called [[WesternAnimation/ThePrinceOfEgypt Jethro]] from destroying both worlds.
* ''WesternAnimation/CentralPark'': [[Theatre/{{Hamilton}} Aaron Burr]] is the manager of Central Park and, alongside his family (wife [[Series/ParksAndRecreation Jennifer Barkley]], son [[Series/UnbreakableKimmySchmidt Titus Andromedon]], and daughter [[WesternAnimation/Frozen2013 Anna]] ([[TheOtherDarrin later]] [[Series/TheUmbrellaAcademy Allison Hargreeves]]), fights to save the park from the machinations of elderly heiress [[Film/TheHungerGames Caesar Flickerman]]. [[Film/BeautyAndTheBeast2017 Le Fou]] is the show's narrator.
* ''WesternAnimation/ChalkZone'': After discovering a piece of magic chalk, [[WesternAnimation/ThePowerpuffGirls Buttercup]] and [[WesternAnimation/AdventureTime Princess Bubblegum]] go into a world made entirely out of chalk drawings, where they meet one of Buttercup's greatest drawings, [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Nick Dean]], and frequently foil the evil plans of WesternAnimation/DarkwingDuck. [[WesternAnimation/FostersHomeForImaginaryFriends Cheese]] is the bully at their school and [[WesternAnimation/SpongeBobSquarePants Squidward]] is a GentleGiant who helps them out sometimes. Buttercup's parents are [[WesternAnimation/{{Animaniacs}} Wakko Warner]] and [[WesternAnimation/TheLandBeforeTime Grandma Longneck]], while Princess Bubblegum's mother is [[WesternAnimation/TheLoudHouse Luna Loud]]. [[WesternAnimation/XMenTheAnimatedSeries Colossus]] is their teacher.
* ''WesternAnimation/{{Chaotic}}'': Friends [[Anime/{{Pokemon}} Cilan, Stephan, Mallow and McGinty]] play cards in a virtual world. Cilan's favorite card is [[Anime/DragonBallZ Goku]], who he transforms into during battles.
* ''WesternAnimation/ElChavoAnimado'': [[Manga/CardcaptorSakura Syaoran Li]] is a poor orphan boy living in urban Mexico. The screwed-up neighbors in this wacky vicinity are the bum [[Manga/LupinTheThird Inspector Zenigata]], the spoiled [[Manga/{{Bleach}} Gin Ichimaru]], his equally snobby mother [[Manga/{{Naruto}} Sakura Haruno]], the witch hag [[WesternAnimation/SouthPark Sheila Broflovski]], the sassy [[WesternAnimation/BlazeAndTheMonsterMachines Starla]], the dumb [[Anime/SailorMoon Ami Mizuno]], the fat guy [[Manga/{{Naruto}} Sasuke Uchiha]], his landlord father [[Franchise/{{Digimon}} Seraphimon]], and the lazy mailman [[Anime/{{FLCL}} Commander Amarao]].
* ''WesternAnimation/ChipAndPotato'': [[WesternAnimation/TopWing Penny]] attends Kindergarten for the first time with her pet and best friend [[WesternAnimation/MyLittlePonyFriendshipIsMagic Pinkie Pie]]. Her parents are [[Series/{{Supernatural}} Donna Hanscum]] and [[Anime/MobileSuitGundamSEEDDestiny Martin DaCosta]], and her older brother is [[Series/AMillionLittleThings Danny Dixon]]. Her teacher is [[Toys/{{Bionicle}} Toa Vakama]]. The school bully is [[WesternAnimation/{{Gigantosaurus}} Leon]]. Penny's best friend's parents are [[Film/AFairlyOddMovieGrowUpTimmyTurner Mrs. Turner]] and [[WesternAnimation/TotalDramarama Chef Hatchet]].
* ''WesternAnimation/ChipNDaleRescueRangers'': [[WesternAnimation/{{Histeria}} Toast]] and [[WesternAnimation/SquirrelBoy Ranger Stu]] are part of a group of animal crimefighters, also consisting of [[WesternAnimation/TinyToonAdventures Babs Bunny]], [[WesternAnimation/TreasurePlanet Onus]], and [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Ultra Lord]] (sometimes [[Franchise/{{Transformers}} Optimus Prime]]). They often fight off an overweight feline named [[WesternAnimation/{{Balto}} Steele]], who was originally owned by [[WesternAnimation/SupermanBatmanPublicEnemies Alfred Pennyworth]], or a MadScientist named [[WesternAnimation/DarkwingDuck Herb Muddlefoot]].
* ''WesternAnimation/ChopChopNinja'': [[WesternAnimation/TrollTheTakeOfATail Jan]], [[VideoGame/AssassinsCreedII Claudia Auditore da Firenze]], [[Anime/{{Bakugan}} Dragonoid]], and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Bow Hothoof]] are a group of young ninjas who defend their dojo from villains like [[WesternAnimation/{{Detentionaire}} Lynch Webber]] and [[Anime/SamuraiPizzaCats Jerry Atric]].
* ''WesternAnimation/{{Chowder}}'': A young boy named [[WesternAnimation/BambiII Flower]] becomes the apprentice of Chef [[VideoGame/CrashBandicoot Papu Papu]], along with his wife [[WesternAnimation/TheSuperheroSquadShow Scarlet Witch]] and his assistant, [[WesternAnimation/AdventureTime Jake the Dog]]. Papu Papu's business rival is [[Film/AustinPowers Frau Farbissina]], whose apprentice, [[WebAnimation/BravestWarriors Beth]], has a massive crush on Flower. Flower is also friends with [[WesternAnimation/AquaTeenHungerForce Master Shake]] and his pet is [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Fred Fredburger]].
* ''WesternAnimation/ChucksChoice'': [[Animation/{{Tobot}} Dylan]] is a 12-year-old boy with a robot named [[WesternAnimation/LittlestPetShopAWorldOfOurOwn Manny Mouser]] who gives him choices that can alter reality - just not always as expected. Accompanying them on their adventures is the tomboy [[Anime/{{InuYasha}} Kagome Hirugashi]]. Dylan's older brother is [[WesternAnimation/EdEddNEddy Rolf]] and [[WesternAnimation/PackagesFromPlanetX Dan Zembrowsky]] is his rival.
* ''WesternAnimation/ClangInvasion'': [[WesternAnimation/{{Spliced}} Two-Legs Joe]], [[WesternAnimation/ScaredySquirrel Sally Fishlips]], and [[WesternAnimation/TheBagelAndBeckyShow Percy]] are three alien robots from Planet Clang who crash land on Earth, where they befriend twins [[WesternAnimation/TotalDrama Sierra]] and [[WesternAnimation/TheAmazingSpiez Tony Clark]]. Sierra and Tony's dog [[WesternAnimation/CreativeGalaxy Pablo]] can speak through a voice box made by the robots.
* ''WesternAnimation/{{Clarence}}'': The show's creator (later [[Series/SantaClaritaDiet Eric Bemis]]), [[Series/TheGoldbergs Adam Goldberg]], and [[WesternAnimation/FostersHomeForImaginaryFriends Eduardo]] have everyday adventures. The school bully is [[Manga/{{Bleach}} Shinji Hirako]] and Eric's mom is [[WesternAnimation/TotalDrama Izzy]], while her boyfriend is [[WesternAnimation/WeBareBears Grizz]] and their teacher is [[WesternAnimation/{{Spliced}} Patricia]].
* ''WesternAnimation/ClassOf3000'': [[WesternAnimation/CampLazlo Mr. Slinkman]], [[WesternAnimation/OzzyAndDrix Osmosis Jones]], [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Libby Folfax]], [[VideoGame/MetroidPrime Samus Aran]], [[Anime/{{Bleach}} Yuzu Kurosaki]], and [[WesternAnimation/MyLifeAsaTeenageRobot Jenny Wakeman]] are students in the music class of [[Music/OutKast the show's creator]]. [[WesternAnimation/CodenameKidsNextDoor Mr. Boss]] is the school's principal.
* ''WesternAnimation/ClassOfTheTitans'': [[Anime/{{InuYasha}} Miroku, Sango]], [[WesternAnimation/XMenEvolution Rogue]] (later [[Anime/TransformersCybertron Lori]]), [[WesternAnimation/DragonTales Ord]], [[WesternAnimation/EdEddNEddy Edd]], [[Anime/TransformersEnergon Cliffjumper]], and [[Manga/DragonBall Yamcha]] are the descendants of Greek heroes who have been brought together to defeat [[Franchise/RatchetAndClank Clank]].
* ''WesternAnimation/CleopatraInSpace'': [[Series/KnightSquad Sage]] is an Egyptian princess transported 30 thousand years into the future to an alien galaxy, where she goes on adventures with her friends [[WesternAnimation/{{Clarence}} Mary Wendell]] and [[WesternAnimation/ElenaOfAvalor Gabe Nuñez]] and her teacher [[Series/{{Heroes}} Mohinder Suresh]]. Together, they battle [[Series/TwoBrokeGirls Oleg Golishevsky]].
* ''Literature/CliffordTheBigRedDog'': [[WesternAnimation/AvatarTheLastAirbender Azula]] adopts [[Series/EightSimpleRules Paul Hennessy]], who grows to gigantic proportions due to Azula's love. Azula's parents, [[WesternAnimation/ScoobyDooMysteryIncorporated Daphne Blake]] and [[VideoGame/WorldOfWarcraft the Blood Elf]], decide to move to Birdwell Island, where Paul becomes friends with [[WesternAnimation/TheSpectacularSpiderMan Glory Grant]], [[Series/AllThat Ed]], and [[VideoGame/MetalGearSolid Liquid Snake]]. Meanwhile, Azula becomes friends with [[VideoGame/DarkForcesSaga Tavion]], [[WesternAnimation/RocketPower Sam, and Twister]]. And their neighbors are [[Anime/KikisDeliveryService Barsa]] and [[VideoGame/MonkeyIsland the Ghost Pirate LeChuck]].
** ''WesternAnimation/CliffordsPuppyDays'': It's revealed that in his youth, Paul was [[WesternAnimation/TheLifeAndTimesOfJuniperLee Juniper Lee]].
* ''WesternAnimation/CloneHigh'': Best friends Film/MacGruber, [[Series/MadTV Stuart]], and [[WesternAnimation/KimPossible Shego]] are clones of famous people attending high school alongside AlphaBitch [[Series/TheDrewCareyShow Kate O'Brien]] and JerkJock [[Series/CarolineInTheCity Cliff. Bill]] is the MadScientist who created them. Also, [[Series/{{Scrubs}} Turk]] has invented an anthropomorphic peanut, [[Series/StarTrekVoyager the EMH Mark II]] is a clinically depressed artist, [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Sheen Estevez]] is a holy carpenter with a Latino accent, and [[Series/BeverlyHills90210 Dylan McKay]] is [[RememberTheNewGuy a guy]] [[LateArrivalSpoiler who dies]]. Also, [[Franchise/BackToTheFuture Marty McFly]] is a lonely kidney.
** (2023 revival): [=MacGruber=], Shego, Kate O'Brien (now [[Series/ThreeBusyDebras Romper Debra]]), and Cliff are unfrozen after 20 years and continue attending high school alongside Bill's new batch of clones, who include [[Series/OrangeIsTheNewBlack Dominga "Daddy" Duarte]], [[WesternAnimation/TeenageMutantNinjaTurtlesMutantMayhem April O'Neil]], [[WesternAnimation/TheGreatNorth Steven Huang]], and [[Film/Ghostbusters2016 Rowan North]]. [[Series/CougarTown Ellie Torres]] is Bill's new boss.
* ''WesternAnimation/CloseEnough'': Married couple [[WesternAnimation/RegularShow Mordecai]] and [[Film/TheHive Jess]] live in a Los Angeles duplex with their daughter [[WesternAnimation/MuppetBabies2018 Summer Penguin]] and their divorced friends [[WesternAnimation/BigMouth Jay Bilzerian]] and [[WesternAnimation/SpiderManSpiderVerse Peni Parker]].
* ''WesternAnimation/CloudyWithAChanceOfMeatballs2017'': [[WesternAnimation/WinstonSteinburgerAndSirDudleyDingDong Cutty]] is an aspiring inventor with a pet monkey named [[WesternAnimation/RocketMonkeys Wally]]. He befriends a weather intern named [[WesternAnimation/{{Braceface}} Nina Harper]], whose cameraman is [[WesternAnimation/EsmeAndRoy Roy]]. Cutty's dad is [[WesternAnimation/SevenLittleMonsters Four]], and the town's mayor is [[WesternAnimation/BestEd Ed]]. Also, [[WesternAnimation/TotalDrama Chef Hatchet]] is the local police officer and [[WesternAnimation/AlmostNakedAnimals Duck]] is the mascot for a sardine company.
* ''WesternAnimation/CoconutFredsFruitSaladIsland'': [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Carl Wheezer]], [[WesternAnimation/ElTigre Rodolfo Rivera]], [[WesternAnimation/TheRenAndStimpyShow Stimpy]], Anime/SailorMoon, and [[Manga/InuYasha Sesshomaru]] are a group of friends who live on a island for fruit. [[Manga/RanmaOneHalf Ryoga Hibiki]] is a frequent rival of Carl.
* ''WesternAnimation/CodenameKidsNextDoor'': VideoGame/{{Mega Man|11}}, [[WesternAnimation/MuppetBabies2018 Baby Gonzo]], [[WesternAnimation/TeenTitans2003 Jinx]], [[WesternAnimation/StarWarsTheCloneWars Captain Rex]], and [[WesternAnimation/{{Rugrats}} Susie Carmichael]] are members of an organization of children who fight villains such as [[Anime/DigimonFusion Shoutmon]], [[WesternAnimation/CowAndChicken Dad]], [[WesternAnimation/TinyToonAdventures Elmyra]], [[Franchise/StarWars Luke Skywalker]], [[WesternAnimation/TransformersPrime Knock Out]], [[VideoGame/FireEmblemFates Takumi]], [[WesternAnimation/HouseOfMouse Mortimer Mouse]] (who becomes [[WesternAnimation/DextersLaboratory Dexter's dad]] when depowered), [[WesternAnimation/{{Animaniacs}} Baloney the Dinosaur]], [[WesternAnimation/TheLoudHouse Lana, Lola, and Lily Loud]], [[WesternAnimation/ThePowerpuffGirls1998 Mayor, Snake, Lil Arturo]], [[Franchise/ScoobyDoo Fred Jones]], [[WesternAnimation/CampLazlo Raj, Samson]], [[WesternAnimation/PhineasAndFerb Perry the Platypus]], [[WesternAnimation/GravityFalls Waddles]], [[WesternAnimation/CatDog Dog]], [[WesternAnimation/StarWarsCloneWars Obi-Wan Kenobi]], [[WesternAnimation/GuardiansOfTheGalaxy2015 Groot]], and [[WesternAnimation/SpongeBobSquarePants Squilliam Fancyson]] (who is actually [[WesternAnimation/FostersHomeForImaginaryFriends Coco]]). Susie's older sister [[WesternAnimation/AtlantisTheLostEmpire Kida]] was a former member of the organization before becoming a teenager and joining the villains. [[WesternAnimation/AmericanDad Hayley Smith]], [[WesternAnimation/TotallySpies Sam]], [[Anime/DigimonTamers Henry Wong]], [[WesternAnimation/MyLifeAsATeenageRobot Jenny Wakeman]], and [[WesternAnimation/HiHiPuffyAmiYumi Ami Onuki]] are also members of the organization as was Baby Gonzo's younger brother [[WesternAnimation/PhineasAndFerb Perry the Platypus]] before going off on his own. Mega Man's girlfriend is [[WesternAnimation/TheFairlyOddParents Vicky]] and his parents are [[WesternAnimation/EvilConCarne Boskov]] and [[WesternAnimation/TheGrimAdventuresOfBillyAndMandy Gladys]], Baby Gonzo and Perry's mother is [[WesternAnimation/MuchaLucha the Headmistress]] and their grandmother is [[WesternAnimation/TheLifeAndTimesOfJuniperLee Ophelia Ramírez]], Jinx's younger sister is WesternAnimation/{{Unikitty}} and her parents are [[WesternAnimation/{{Futurama}} Amy Wong]] and [[Series/{{Deadwood}} Mr. Wu]], Rex's baby brother is [[WesternAnimation/AvatarTheLastAirbender Appa]] and his parents are [[WesternAnimation/AmericanDragonJakeLong Jonathan Long]] and [[VideoGame/MetroidPrime Samus Aran]], and Susie and Kida's parents are [[WesternAnimation/TheClevelandShow Cleveland Jr.]] and [[WesternAnimation/DannyPhantom Valerie Grey]]. [[WesternAnimation/TheTransformers Bonecrusher]] is a KnightOfCerebus who is the father of Mortimer [[spoiler:and Boskov, who was [[Anime/DigimonFrontier Trailmon]] in his youth]].
* ''WesternAnimation/{{Committed}}'': [[Series/SchittsCreek Johnny and Moira Rose]] have three children, who are [[WesternAnimation/{{Franklin}} Skunk]], [[Series/NaturallySadie Sadie Hawthorne]], and [[WesternAnimation/RoliePolieOlie Olie Polie]]. [[WesternAnimation/ABugsLife Flik]] is their pet.
* ''WesternAnimation/CoolMcCool'': WesternAnimation/MiltonTheMonster is a hip, trenchcoat-wearing superspy who always manages to thwart villainy despite his ineptness.
* ''[[WesternAnimation/COPS1988 C.O.P.S.]]'': [[Series/TheXFiles Walt Eubanks]], [[WesternAnimation/DogCity Bugsy Vile]], [[WesternAnimation/{{Dinosaucers}} Ankylo]], [[Film/DeadRingers Leo]], [[WesternAnimation/CareBears1980s Professor Coldheart]], [[WesternAnimation/{{Babar}} Madame]], [[WesternAnimation/{{Cyberchase}} Buzz]], [[Series/AlfredHitchcockPresents Max Cantilever]], [[Series/{{Wiseguy}} Crawley]], WesternAnimation/{{Jayce|AndTheWheeledWarriors}}, [[WesternAnimation/RubyGloom Scaredy Bat]], and [[Anime/SailorMoon JunJun]] are a team of police officers who thwart the criminal enterprises of [[WesternAnimation/TheLegendOfZelda1989 Ganondorf]] and his henchmen [[Series/TheLAComplex Ron Jacobs]], [[WesternAnimation/DiGataDefenders Flinch]], [[Series/KingOfKensington Speedy]], WesternAnimation/CliffordTheBigRedDog, [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rarity]], [[WesternAnimation/LittleBear Father Bear]], [[Film/ShortCircuit2 a robotics company executive]], and [[WesternAnimation/TheRaccoons Cedric Sneer]].
* ''WesternAnimation/CornAndPeg'': [[WesternAnimation/CliffordTheBigRedDog2019 Pablo]] (formerly [[WesternAnimation/LetsGoLuna Andy Hopper]]) and [[WesternAnimation/BluesCluesAndYou Paprika]] are inspired by their TV hero [[WesternAnimation/CupcakeAndDinoGeneralServices Mayor Vicky]] to always do good around their town.
* ''WesternAnimation/CosmicQuantumRay'': [[WesternAnimation/SpongeBobSquarePants Gary the Snail]] is a superhero who teams up with [[WesternAnimation/EdEddNEddy Double D]], Anime/{{Hamtaro}}, [[WesternAnimation/MyLittlePonyFriendshipIsMagic Snails]], [[WesternAnimation/CareBearsAdventuresInCareALot Oopsy Bear]], and [[WesternAnimation/CaptainNTheGameMaster Kevin Keene]] to defeat villains like [[WesternAnimation/{{CatDog}} Cliff]] and [[WesternAnimation/CampLazlo Slinkman]].
* ''WesternAnimation/CowAndChicken'': [[WesternAnimation/TinyToonAdventures Buster Bunny]] and [[WesternAnimation/AaahhRealMonsters Ickis]] are siblings who are constantly harassed by [[WesternAnimation/SonicTheHedgehogSatAM Snively]]. Their parents are [[WesternAnimation/StarWarsTheCloneWars Captain Rex]] and [[WesternAnimation/MyLifeAsATeenageRobot Nora Wakeman]] and their best friends are [[WesternAnimation/TheSimpsons Homer Simpson]] and [[WesternAnimation/TheManyAdventuresOfWinnieThePooh Gopher]] ([[WesternAnimation/TheLooneyTunesShow Yosemite Sam]] in one episode). [[WesternAnimation/TinyToonAdventures Sweetie Pie]] is their teacher.
** ''WesternAnimation/IAmWeasel'': [[Series/StarTrekTheNextGeneration Worf]] is an intellectual celebrity, while [[WesternAnimation/RockosModernLife Ed Bighead]] is always trying to outdo him. Occasionally, Snively shows up to annoy the two.
* ''WesternAnimation/CraigOfTheCreek'': [[Film/HeroMode Nick Williams]] goes to the Creek, the woods behind his house, every day to have fun with his best friends [[WesternAnimation/StarTrekLowerDecks D'Vana Tendi]] (formerly [[WesternAnimation/{{Jellystone}} Augie Doggie]]) and [[WesternAnimation/{{Unikitty}} Brock]]. Other residents of the Creek include [[Series/{{Heroes}} Monica Dawson]], [[WesternAnimation/KungFuPandaThePawsOfDestiny Bao]], [[WesternAnimation/SheRaAndThePrincessesOfPower Glimmer]], [[WesternAnimation/LegoStarWarsAllStars Moxie]], [[WebAnimation/TrickMoon Trickshot]], [[VideoGame/{{Overwatch}} D.va]], [[WesternAnimation/TheLoudHouse Ronnie Anne Santiago]], and [[DescendedCreator the show's creators]]. Nick lives with his father [[Film/TheExpendables Hale Caesar]], his mother [[Series/KevinProbablySavesTheWorld Yvette]], and his older brother [[WesternAnimation/SamuraiJack Jack]] (who's dating [[Film/SuicideSquad2016 Katana]]); his grandparents are [[WesternAnimation/AtlantisTheLostEmpire Joshua Sweet]] and [[Series/ThirdWatch Mary Proctor]]. The kids eventually explore the Other Side of the Creek, ruled by [[WesternAnimation/TrollsTrollstopia Demo]] and his "BFF" [[WesternAnimation/KipoAndTheAgeOfWonderbeasts Wolf]], whom [[Anime/PokemonJourneysTheSeries Goh]] keeps from invading.
* ''WesternAnimation/TheCrampTwins'': [[WesternAnimation/SquirrelBoy Leon]] and [[WesternAnimation/TinyToonAdventures Fifi La Fume]] are siblings living in Soap City who constantly do [[{{Squick}} gross things]] to each other. Their parents are [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Celestia]] and WesternAnimation/{{Mega Man|RubySpears}} and they frequently hang out with [[WesternAnimation/EdEddNEddy Eddy's Brother]]. Leon also has a friend named [[WesternAnimation/LeagueOfSuperEvil Doktor Frogg]] who owns the local dump.
* ''WesternAnimation/CrashCanyon'': [[WesternAnimation/{{Sidekick}} Professor Pampelmoose]], his wife [[Series/EastboundAndDown Cassie Powers]], his kids [[WesternAnimation/{{Grojband}} Laney Penn]] and [[WesternAnimation/MyDadTheRockStar Willy Zilla]], and his cousin [[WesternAnimation/TheAdventuresOfSamAndMaxFreelancePolice Lorne]] live in a community located at the bottom of a canyon.
* ''WesternAnimation/TheCritic'': [[Series/SaturdayNightLive Tommy Flanagan, the Pathological Liar]] is New York's #3 film critic. He tries to do right by his son [[WesternAnimation/{{Rugrats}} Chuckie Finster]], but is often verbally abused by his makeup lady [[WesternAnimation/TheSimpsons Lunchlady Doris]] and his boss [[WesternAnimation/{{Squidbillies}} the Sheriff]]. He finds love with [[Series/EmptyNest Laverne Higby]]. He is good friends with [[WesternAnimation/PinkyAndTheBrain the Brain]].
* ''WesternAnimation/CrusaderRabbit'': [[WesternAnimation/InvaderZIM Ms. Bitters]] (later [[WesternAnimation/LooneyTunes Granny]]) is a rabbit who goes on crusades with her tiger sidekick.[[note]]Vern Louden, Ragland T. Tiger's voice actor, has no other credits.[[/note]]
* ''WesternAnimation/CupcakeAndDinoGeneralServices'': [[Series/MurdochMysteries Buck Christopher]] and WesternAnimation/{{Gary|AndHisDemons}} are a sibling duo who make a living by performing various odd jobs around their hometown. Their grandmother is [[Anime/{{Bakugan}} Runo Misaki]] and [[Series/MissPersona Jason]] is their uncle. [[Series/{{Letterkenny}} Coach]] is their business assistant; [[WesternAnimation/NumbChucks Woodchuck Morris]] is their rival; and [[WesternAnimation/ThreeAmigonauts Kirbie]] is the mayor of their town.
* ''WesternAnimation/TheCupheadShow'': [[VideoGame/Psychonauts2 Adam Joseph Gette]] and [[Manga/TheVampireDiesInNoTime Draluc]] get into misadventures around Inkwell Isle, occasionally being joined by their friend [[WesternAnimation/DannyPhantom Sam Manson]].
* ''WesternAnimation/CuriousGeorge'': [[WesternAnimation/ExtremeGhostbusters Eduardo Rivera]] (originally [[Series/ShamelessUS Frank Gallagher]]) narrates the adventures of [[WesternAnimation/{{Aladdin}} Abu]], a mischievous monkey who lives with WesternAnimation/JohnnyBravo.
* ''WesternAnimation/{{Cyberchase}}'': [[Anime/{{Medabots}} Rintarou Namishima]], [[WesternAnimation/TotalDrama Leshawna, and Sierra]] are three kids who team up with a cyborg bird named [[WesternAnimation/{{Aladdin}} Iago]] (later WesternAnimation/MarvinTheTapDancingHorse) to stop the evil plans of [[Franchise/BackToTheFuture Doc Brown]] and his henchmen [[WesternAnimation/DonkeyKongCountry Krusha]] (later [[WesternAnimation/StickinAround Stanley Stickler]]) and [[WesternAnimation/AlmostNakedAnimals Howie]] to rule cyberspace, which is protected by [[WesternAnimation/MissSpidersSunnyPatchFriends Spindella]] and her technician [[WesternAnimation/MyFriendRabbit Mouse]].
* ''WesternAnimation/{{Cybersix}}'': [[WesternAnimation/MyLittlePonyFriendshipIsMagic Spike]] is an android who works as a teacher by day and battles his creator [[Anime/DragonBallZ Krilin]] by night. He is helped out by his friend and co-worker [[Anime/TransformersArmada Starscream]], his student [[WesternAnimation/EdEddNEddy Sarah]], and a street urchin named [[Toys/{{Bionicle}} Jaller]]. Krilin's son and second-in-command is [[Anime/InuYasha Kohaku]], while [[Anime/DeathNote Ryuk]] is a detective.
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