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[[quoteright:350:https://static.tvtropes.org/pmwiki/pub/images/simpsonscast.jpg]]
[[caption-width-right:350:The main cast. Not pictured: one of the most epic lists of guest stars in the history of television.]]
An index for the voice actors and voice actresses of ''WesternAnimation/TheSimpsons'' who have a page on TV Tropes.
----
[[foldercontrol]]
!!Series, Specials & Film
[[folder:Regular cast]]
!!Main cast
* Creator/DanCastellaneta: Homer Jay Simpson, Abraham "Abe" Jedediah Simpson II, Herschel "Krusty the Clown" Krustofski, Barney Gumble, Groundskeeper Willie, Mayor Joseph Quimby, Hans Moleman, Sideshow Mel, Gil Gunderson, Squeaky Voiced Teen, Kodos, Itchy.
* Creator/JulieKavner: Marjorie "Marge" Jacqueline Simpson (née Bouvier), Jacqueline Ingrid Bouvier (née Gurney), Patricia "Patty" Bouvier, Selma Bouvier.
* Creator/NancyCartwright: Bartholomew "Bart" Jo-Jo Simpson, Margaret "Maggie" Evelyn Simpson (later seasons), Ralph Wiggum, Nelson Muntz, Kearney, Todd Flanders, Ling Bouvier.
* Creator/YeardleySmith: Lisa Marie Simpson, Margaret "Maggie" Evelyn Simpson (earlier seasons).
* Creator/HankAzaria: Apu Nahasapeemapetilon, Morris "Moe" Szyslak, Carl Carlson (seasons 1-31), Chief Clarence "Clancy" Wiggum, Officer Lou (seasons 1-31), Jeffrey "Comic Book Guy" Albertson, Kirk Van Houten, Professor John Frink Jr., Superintendent Gary Chalmers, Cletus Spuckler, Snake Jailbird, Captain Horatio [=McCallister=], Bumblebee Man (seasons 4-31), Disco Stu, Dr. Nick Riviera, Duffman.
* Creator/HarryShearer: Nedward "Ned" Flanders, Charles "Monty" Montgomery Burns, Waylon J. Smithers Jr., Principal W. Seymour Skinner, Lenny Leonard, Kent Brockman, Reverend Timothy Lovejoy, Dr. Julius Hibbert (seasons 2-31), Judge Roy Snyder (seasons 1-31) Otto Man, Jasper Beardley, Rainier Wolfcastle, Kang, Scratchy.
!!Recurring cast
* Creator/SusanBlu: Various supporting characters in season 1.
* Creator/AlbertBrooks: Cowboy Bob, Jacques, Brad Goodman, Hank Scorpio, Tab Spangler, Russ Cargill, French Guy, Dr. Raufbold.
* Creator/KimberlyBrooks: Janey Powell, Lewis Clark (since season 32).
* Creator/GlennClose: Mona Simpson.
* Christopher Collins: Mr. Burns (season 1 only, replaced by Harry Shearer).
* Creator/GreyDeLisle: Sherri Mackleberry, Terri Mackleberry, Martin Prince, Üter Zörker (since season 31).
* Creator/AlexDesert: Carl Carlson, Officer Lou (since season 32).
* Chris Edgerly: Various supporting characters,.
* Marcia Mitzman Gaven: Replaced Maggie Roswell (seen below) for seasons 11-14.
* Creator/DanaGould: Himself, Murphy, Air Marshall, Barney Fife, Producer, Various.
* Creator/KelseyGrammer: Robert "Sideshow Bob" Terwilliger.
* Doris Grau: Lunchlady Doris (eventually replaced by Tress [=MacNeille=] after her death)
* Creator/PamelaHayden: Milhouse Van Houten, Jimbo Jones, Rod Flanders, Janey Powell, Sarah Wiggum.
* Jo Ann Harris: Various supporting characters (until season 4).
* Creator/PhilHartman: Lionel Hutz, Troy [=McClure=].
* Creator/JanHooks: Manjula Nahasapeemapetilon (replaced by Tress [=MacNeille=] after her death)
* Creator/JaneKaczmarek: Judge Constance Harm.
* Creator/MauriceLaMarche: Various supporting characters (since season 6).
* Creator/DawnnLewis: Berince Hibbert (since season 32).
* Creator/EricLopez: Bumblebee Man (since season 32)/Gambling Man/Lisa's Student.
* Creator/NatashaLyonne: Sophie (since season 28).
* Creator/TressMacNeille: Agnes Skinner, Lindsey Naegle, Brandine Spuckler, Crazy Cat Lady, Cookie Kwan, Bernice Hibbert, Manjula Nahasapeemapetilon, Lunchlady Doris, Dolph Starbeam, Kumiko Albertson (seasons 25-31).
* Creator/JoeMantegna: Fat Tony.
* Jackie Mason: Hyman Krustofsky.
* Creator/MeganMullally: Sarah Wiggum (since season 32).
* Creator/JayPharoah: Drederick Tatum (since season 33).
* Creator/PamelaReed: Ruth Powers.
* Creator/KevinMichaelRichardson: Dr. Julius Hibbert, Judge Roy Snyder (since season 32), Anger Watkins.
* Creator/AlexRocco: Roger Meyers Jr.
* Tony Rodriguez: Julio Franco (since season 32).
* Maggie Roswell: Elizabeth Hoover, Maude Flanders, Helen Lovejoy, Luann Van Houten, Mary Bailey, Princess Kashmir, Martha Quimby.
* Creator/RussiTaylor: Sherri Mackleberry, Terri Mackleberry, Martin Prince, Wendell Borton, Üter Zörker (until season 30)
* Creator/ScottThompson: Grady.
* Creator/MarciaWallace: Edna Krabappel.
* Creator/KerryWashington: Rayshelle Peyton.
* Karl Wiedergott: Various secondary characters (until season 22).
* Creator/FrankWelker: Santa's Little Helper, Snowball II, various animals.
* Creator/JennyYokobori: Kumiko Albertson (since season 32)
[[/folder]]
[[folder:Guest stars]]
!!A-F
* Music/FiftyCent: Himself in Episode #344 "Pranksta Rap".
* {{Music/Aerosmith}}: Themselves in Episode #45 "Flaming Moe's".
* Creator/ShohrehAghdashloo: Mina bin Laden in Episode #427 "Mypods and Broomsticks".
* Creator/JasonAlexander: Bourbon Verlander in Episode #615 "Caper Chase".
* Music/AlisonKraussAndUnionStation: They perform the theme song in Episode #500 "At Long Last Leave".
* Creator/SteveAllen:
** Electronically altered voice of Bart in Episode #53 "Separate Vocations".
** Himself in Episode #125 "'Round Springfield".
* Creator/UtkarshAmbudkar: Jay Nahasapeemapetilon in Episode #586 "Much Apu About Something".
* Creator/GillianAnderson: [[Series/TheXFiles Dana]] [[AgentScully Scully]] in Episode #163 "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]".
* Creator/AndreAgassi: Himself in Episode #260 "Tennis the Menace".
* Creator/JuddApatow: Himself in Episode #539 "Steal This Episode".
* Creator/FredArmisen: Terrence in Episode #515 "The Day the Earth Stood Cool" and #745 "Pin Gal".
* Creator/WillArnett: Deputy Director Gratman in Episode #539 "Steal This Episode".
* Creator/TomArnold: Himself in Episode #230 "Treehouse of Horror X".
* Creator/EdwardAsner: Newspaper editor in Episode #229 "Guess Who's Coming to Criticize Dinner?".
* Creator/DanAykroyd: Postage Stamp Fellow in Episode #695 "The Dad-Feelings Limited".
* Creator/DiedrichBader: Sheriff in Episode #245 "Kill the Alligator and Run".
* Creator/ScottBakula: Himself in Episode #672 "Bobby, It's Cold Outside".
* Creator/BobBalaban: Narrator in Episode #695 "The Dad-Feelings Limited".
* Creator/AlecBaldwin:
** Himself in Episode #208 "When You Dish Upon a Star".
** Caleb Thorn in Episode #357 "Bonfire of the Manatees".
* Creator/AnneBancroft: Dr. Zweig in Episode #114 "Fear of Flying".
* Creator/ElizabethBanks: Persephone Odair in Episode #754 "Thirst Trap: A Corporate Love Story".
* Creator/ChristineBaranski: Herself in Episode #714 "Portrait of a Lackey on Fire".
* Creator/SachaBaronCohen: Jakob in Episode #457 "The Greatest Story Ever D'ohed".
* Creator/DrewBarrymore: Sophie in Episode #251 "Insane Clown Poppy".
* Creator/AngelaBassett: [[UsefulNotes/BarackObama Michelle Obama]] in Episode #456 "Stealing First Base".
* Creator/MarioBatali: Himself in #491 "The Food Wife" and #622 "Treehouse of Horror XXVIII".
* Creator/JasonBateman: Himself in Episode #355 "Home Away from Homer".
* Creator/BryanBatt: Philip Hefflin/Carl in Episode #650 "Mad About the Toy".
* Creator/EdBegleyJr: Himself in Episode #216 "Homer to the Max" and #433 "Gone Maggie Gone".
* Creator/KristenBell: Harper Jambowski in Episode #580 "Friend with Benefit".
* Music/BelleAndSebastian: Themselves in Epsiode #758 "Ae Bonny Romance".
* Creator/HJonBenjamin: [[WesternAnimation/BobsBurgers Bob Belcher]] in Episode #642 "My Way or the Highway to Heaven".
* Music/TonyBennett: Himself in #18 "Dancin' Homer" and #294 "Bart vs. Lisa vs 3rd Grade" and #527 "Whiskey Business".
* Creator/GreggBerger: Various animals in Episode #471 "How Munched Is That Birdie in the Window?".
* Creator/HalleBerry: Herself in Episode #478 "Angry Dad: The Movie".
* Music/JustinBieber: Himself in Episode #528 "The Fabulous Faker Boy".
* Creator/JackBlack: Milo in Episode #407 "Husbands and Knives".
* UsefulNotes/TonyBlair: [[PoliticianGuestStar Himself]] in Episode #317 "The Regina Monologues".
* Creator/CateBlanchett: Elaine Wolff in Episode #684 "The Way of the Dog".
* Music/Blink182: Themselves in Episode #302 "Barting Over".
* Creator/RachelBloom: Annette in Episode #620 "Springfield Splendor".
* Creator/EmilyBlunt: Juliet Hobbes in Episode #429 "Lisa the Drama Queen".
* Creator/BobTheDragQueen: Herself in Episode #740 "My Life as a Vlog".
* Creator/PeterBogdanovich: Psychologist in Episode #392 "Yokel Chords".
* Creator/ErnestBorgnine: Himself in Episode #89 "Boy-Scoutz 'n the Hood".
* Creator/AnthonyBourdain: Himself in Episode #491 "The Food Wife".
* Creator/BillyBoyd: Himself in Episode #619 "The Serfsons".
* Creator/RussellBrand: Himself in Episode #478 "Angry Dad: The Movie".
* Creator/JamesLBrooks: [[CreatorCameo Himself]] in Episode #304 "A Star Is Born Again".
* Creator/MelBrooks: Himself in Episode #120 "Homer vs. Patty and Selma".
* Creator/PierceBrosnan: Ultrahouse's Pierce Brosnan voice and Himself in Episode #270 "Treehouse of Horror XII".
* Music/JamesBrown: Himself in Episode #88 "Bart's Inner Child".
* Creator/WrenTBrown: Virgil in Episode #454 "The Color Yellow".
* Creator/CarrieBrownstein: Emily in Episode #515 "The Day the Earth Stood Cool".
* Creator/HannibalBuress: Principal Finch in Episode #692 "The Road to Cincinnati"
* Creator/BillBurr: Townie, Man in Tunnel, Cart-Warning Man in Episode #599 "The Town".
* Creator/SteveBuscemi:
** Himself in Episode #311 "Brake My Wife, Please".
** Dwight David Diddlehoffer in Episode #404 "I Don't Wanna Know Why the Caged Bird Sings".
* Creator/GaryBusey: Himself in Episode #346 "On a Clear Day I Can't See My Sister".
* Music/DavidByrne: Himself in Episode #309 "Dude, Where's My Ranch?" and Episode #502 "How I Wet Your Mother".
* Creator/JamesCaan: Himself in Episode #337 "All's Fair in Oven War"
* Creator/NeveCampbell: Cassandra in Episode #448 "Rednecks and Broomsticks".
* Creator/LizzyCaplan: Virginia Johnson in Episode #612 "Kamp Krustier".
* Creator/SteveCarell: Dan Gillick in Episode #513 "Penny Wiseguys".
* Creator/DrewCarey: Himself in Episode #420 "All About Lisa".
* Creator/GeorgeCarlin: Munchie in Episode #209 "D'oh-in in the Wind".
* Music/JohnnyCash: Coyote in Episode #162 "The Mysterious Voyage of Homer".
* Creator/KimCattrall: Chloe Talbot in Episode #339 "She Used to Be My Girl".
* Creator/DickCavett: Himself in Episode #118 "Homie the Clown".
* Creator/MichaelCera: Nick in Episode #499 "The Daughter Also Rises".
* Creator/DonCheadle: Brother Faith in Episode #237 "Faith Off".
* Creator/CheechAndChong: Themselves in Episode #480 "A Midsummer's Nice Dream".
* Creator/MichaelChiklis: Handsome Boston quarterback in Episode #599 "The Town".
* Creator/TomClancy: Himself in Episode #323 "Diatribe of a Mad Housewife".
* Creator/DickClark: Himself in Episode #230 "Treehouse of Horror X".
* [[Music/FlightOfTheConchords Jermaine Clement]]: Ethan Ballantyne in Episode #465 "Elementary School Musical".
* Creator/StephenColbert: Colby Kraus in Episode #401 "He Loves to Fly and He D'ohs".
* Creator/GaryColeman: Himself in Episode #235 "Grift of the Magi", #250 "A Tale of Two Springfields", and #261 "Day of the Jackanapes".
* Creator/OliviaColman: Lily in Episode #689 "The 7 Beer Itch".
* Creator/TimConway: Himself in Episode #177 "The Simpsons Spin-off Showcase".
* Creator/SteveCoogan: Rowan Priddis in Episode #505 "A Totally Fun Thing That Bart Will Never Do Again".
* Creator/AndersonCooper: Himself in Episode #536 "The Kid Is All Right".
* Creator/BrianCox: Kostas Becker in Episode #712 "A Serious Flanders".
* Creator/BryanCranston:
** Stradivarius Cain in Episode #506 "The Spy Who Learned Me".
** [[Series/BreakingBad Walter White]] ([[MediumBlending live action]]) in Episode #525 "What Animated Women Want" (CouchGag).
* Music/DavidCrosby: Himself in Episode #80 "Marge in Chains" and Episode #82 "Homer's Barbershop Quartet".
* Creator/MarkCuban: Himself in Episode #428 "The Burns and the Bees".
* Creator/BenedictCumberbatch: British Prime Minister in Episode #520 "Love Is a Many-Splintered Thing".
* Creator/AlanCumming: Loki in Episode #708 "Bart's in Jail!".
* Creator/WillemDafoe:
** Commandent in Episode #178 "The Secret War of Lisa Simpson".
** Jack Lassen in Episode #559 "Blazed and Confused".
* Creator/AndyDaly: Judge Dowd in #632 "Fears of a Clown".
* Creator/RodneyDangerfield: Larry Burns in Episode #157 "Burns, Baby Burns".
* Creator/WilliamDaniels: KITT in Episode #205 "The Wizard of Evergreen Terrace".
* Creator/TedDanson: Sam Malone in Episode #114 "Fear of Flying".
* UsefulNotes/RichardDawkins: Himself in Episode #523 "Black Eyed, Please".
* Creator/EllenDeGeneres: Herself in Episode #464 "Judge Me Tender".
* Creator/GuillermoDelToro: Himself in Episode #654 "101 Mitigations".
* Creator/KatDennings: Valerie in Episode #626 "Mr. Lisa's Opus".
* Creator/EmilyDeschanel: Herself in Episode #640 "Bart's Not Dead".
* Creator/ZooeyDeschanel: Mary Spuckler in Episode #417 "Apocalypse Cow", Episode #509 "Moonshine River" and Episode #520 "Love is a Many-Splintered Thing".
* Creator/DannyDeVito: Herb Powell in Episode #28 "Oh Brother, Where Art Thou?", Episode #59 "Brother, Can You Spare Two Dimes?" and Episode #519 "The Changing of the Guardian".
* Creator/JohnDiMaggio: [[{{WesternAnimation/Futurama}} Bender]] in Episode #350 "Future-Drama", Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]", and ''VideoGame/TheSimpsonsGame''.
* Creator/AndyDick: Himself in Episode #392 "Yokel Chords".
* Creator/MattDillon: Louie in Episode #403 "Midnight Towboy".
* Music/DixieChicks: Themselves in Episode #416 "Papa Don't Leech".
* Creator/KirkDouglas: Chester J. Lampwick in Episode #146 "The Day the Violence Died".
* Creator/FranDrescher: Female Golem in Episode #382 "Treehouse of Horror XVII".
* Creator/AdamDriver: Adam Sackler in Episode #575 "Every Man's Dream".
* Creator/DavidDuchovny: [[Series/TheXFiles Fox]] [[AgentMulder Mulder]] in Episode #163 "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]".
* Creator/OlympiaDukakis: Zelda in Episode #282 "The Old Man and the Key".
* Creator/LenaDunham: Candace, Hannah Helene Horvath in Episode #575 "Every Man's Dream".
* Creator/BillyEichner: Billy in Episode #647 "Krusty the Clown" and #746 "Fan-ily Feud".
* Creator/HarlanEllison: Himself in Episode #540 "Married to the Blob".
* Creator/RobertEnglund: [[Franchise/ANightmareOnElmStreet Freddy Krueger]] in Episode #207 "Treehouse of Horror IX".
* Creator/RLeeErmey: Colonel Leslie Hapablap in Episode #137 "Sideshow Bob's Last Gleaming" and Episode #569 "Waiting for Duffman".
* Creator/MorganFairchild: Vivienne St. Charmaine in Episode #690 "Podcast News".
* Music/FallOutBoy: They perform the ending theme song in Episode #429 "Lisa the Drama Queen".
* Creator/AnnaFaris: Ashley in Episode #731 "Lisa the Boy Scout".
* Creator/TinaFey: Ms. Cantwell in Episode #523 "Black-Eyed, Please".
* Creator/NathanFielder: Doug Blattner in Episode #568 "Sky Police".
* Creator/HarveyFierstein: Karl in Episode #15 "Simpson and Delilah".
* Creator/FyvushFinkel: AsHimself playing Krusty in Episode #181 "Lisa's Sax".
* Creator/MiriamFlynn: Miss Barr in Episode #6 "Moaning Lisa".
* Creator/JaneFonda: Maxine Lombard in Episode #557 "Opposites A-Frack".
* Creator/JuneForay: Babysitting Lady in Episode #13 "Some Enchanted Evening".
* Creator/WillForte: King Toot in Episode #560 "Covercraft".
* Creator/JodieFoster: Maggie Simpson in Episode #440 "Four Great Women and a Manicure".
* Creator/BrendanFraser: Brad in Episode #201 "King of the Hill".
* Creator/StephenFry: Terrance in Episode #705 "The Man from G.R.A.M.P.A."
!!G-L
* Creator/GalGadot: Herself in Episode #640 "Bart's Not Dead".
* Creator/NeilGaiman:
** Himself in Episode #492 "The Book Job".
** Snowball II in Episode #622 "Treehouse of Horror XXVIII".
* Creator/ZachGalifianakis: Lucas Bortner in Episode #547 "Luca$".
* Creator/VictorGarber: Michael in Episode #714 "Portrait of a Lackey on Fire".
* Creator/AndyGarcia: Slick Publisher in Episode #492 "The Book Job".
* Creator/JaneaneGarofalo: Herself in Episode #193 "The Last Temptation of Krust" and Episode #494 "The Ten-Per-Cent Solution".
* Creator/SarahMichelleGellar: Gina Vendetti in Episode #329 "The Wandering Juvie" and Episode #509 "Moonshine River".
* Creator/BrianGeorge: [=MI5=] Agents in Episode #705 "The Man from G.R.A.M.P.A."
* Creator/RichardGere: Himself in Episode #275 "She of Little Faith".
* Creator/RickyGervais: Charles Heathbar in Episode #371 "Homer Simpson, This is Your Wife".
* Creator/MelGibson: Himself in Episode #227 "Beyond Blunderdome".
* Creator/KarenGillan: Maisie [=MacWeldon=] in Episode #758 "Ae Bonny Romance".
* Creator/JeffGoldblum: [=MacArthur=] Parker in Episode #147 "A Fish Called Selma".
* Creator/JohnGoodman: Meathook in Episode #234 "Take My Wife, Sleaze".
* UsefulNotes/DorisKearnsGoodwin: Herself in #599 "The Town".
* Creator/ElliottGould: Elliott Gould in Episode #299 "The Dad Who Knew Too Little".
* Creator/TopherGrace: Donny in Episode #413 "The Debarted".
* Creator/SethGreen: Mav Redfield in Episode #727 "Meat is Murder".
* Music/GreenDay: Themselves in ''WesternAnimation/TheSimpsonsMovie''.
* Creator/KathyGriffin: Francine in Episode #264 "Bye Bye Nerdie".
* Creator/MattGroening: [[CreatorCameo Himself]] in multiple episodes of the show, along with ''VideoGame/TheSimpsonsGame''.
* Creator/JonathanGroff: Actor Bart in Episode #640 "Bart's Not Dead".
* Creator/ChristopherGuest: Nigel Tufnel in Episode #57 "The Otto Show".
* Creator/BillHader:
** Slava in Episode #528 "The Fabulous Baker Boy".
** Manacek in Episode #630 "Homer is Where the Art Isn't."
* Creator/LarryHagman: Wallace Brady in Episode #377 "The Monkey Suit".
* Creator/MarkHamill: Himself, Leavelle, Theater Owner in Episode #212 "Mayored to the Mob".
* Creator/JonHamm: FBI Agent in Episode #473 "Donnie Fatso".
* Creator/ArmieHammer: Cameron Winklevoss, Tyler Winklevoss in Episode #497 "The D'oh-cial Network".
* Creator/TomHanks: Himself in ''WesternAnimation/TheSimpsonsMovie''.
* Creator/AlysonHannigan: Melody Juniper in Episode #475 "Flaming Moe".
* Creator/DavidHarbour: Fred Kranepool in Episode #685 "Undercover Burns".
* Creator/DanHarmon: Himself in Episode #620 "Springfield Splendor".
* Creator/JessHarnell: Various animals in Episode #271 "The Parent Rap".
* Creator/ValerieHarper:
** Proctor Perkins in Episode #518 "A Test Before Trying".
** Ms. Myles in Episode #626 "Mr. Lisa's Opus".
* Creator/WoodyHarrelson: Woody Boyd in Episode #114 "Fear of Flying".
* Creator/NeilPatrickHarris: Himself in Episode #39 "Bart the Murderer".
* Music/GeorgeHarrison: Himself in Episode #82 "Homer's Barbershop Quartet".
* Creator/AnneHathaway:
** Jenny in Episode #437 "The Good, the Sad and the Ugly" and Episode #509 "Moonshine River".
** Princess Penelope in Episode #451 "Once Upon a Time in Springfield".
* Creator/TonyHawk: Himself in Episode #302 "Barting Over".
* Creator/StephenHawking: Himself in Episode #225 "They Saved Lisa's Brain", Episode #351 "Don't Fear The Roofer", Episode #398 "Stop or My Dog Will Shoot!", and Episode #465 "Elementary School Musical".
* Creator/TarajiPHenson: Praline in Episode #608-609 "The Great Phatsby".
* Creator/DavidHerman: [[{{WesternAnimation/Futurama}} Scruffy]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
* Creator/DonHertzfeldt: "The Sampsans" in Episode #553 "Clown in the Dumps" (CouchGag).
* Creator/WernerHerzog: Walter Hotenhoffer in Episode #479 "The Scorpion's Tale".
* Creator/JonahHill: Andy Hamilton in Episode #447 "Pranks and Greens".
* Creator/DustinHoffman: Mr. Bergstrom in Episode #32 "Lisa's Substitute".
* Creator/BobHope: Himself in Episode #63 "Lisa the Beauty Queen".
* Creator/RonHoward: Himself in Episode #208 "When You Dish Upon a Star" and Episode #232 "Hello Gutter, Hello Fadder".
* Creator/HelenHunt: Renee in Episode #194 "Dumbell Indemnity".
* Creator/EricIdle: Declan Desmond in Episode #307 "Scuse Me While I Miss the Sky", Episode #340 "Fat Man and Little Boy", Episode #391 "Springfield Up" and Episode #506 "The Spy Who Learned Me".
* Creator/JeremyIrons: Bar Rag in Episode #498 "Moe Goes from Rags to Riches".
* Creator/SuzyEddieIzzard: Nigel Bakerbutcher in Episode #461 "To Surveil With Love".
* Creator/HughJackman: Janitor in Episode #728 "Poorhouse Rock".
* Creator/JoshuaJackson: Jesse Grass in Episode #252 "List the Tree Hugger".
* Music/MichaelJackson: Leon Kompowsky in Episode #36 "Stark Raving Dad".
* Creator/PeterJackson: Himself in Episode #754 "Thirst Trap: A Corporate Love Story".
* Music/MickJagger: Himself in Episode #293 "How I Spent My Strummer Vacation".
* UsefulNotes/LeBronJames: Himself in Episode #343 ""Homer and Ned's Hail Mary Pass".
* Creator/AllisonJanney: Julia in Episode #598 "Friends and Family".
* Music/EltonJohn: Himself in Episode #217 "I'm with Cupid".
* Creator/JamesEarlJones:
** Moving Man, Serak the Preparer, ''[[Creator/EdgarAllanPoe The Raven]]'' Narrator in Episode #16 "Treehouse of Horror".
** Alternate universe Maggie Simpson in Episode #109 "Treehouse of Horror V".
* Creator/RashidaJones: Portia in Episode #519 "The Changing of the Guardian".
* Music/TomJones: Himself in Episode #66 "Marge Gets a Job".
* Creator/MikeJudge: [[WesternAnimation/KingOfTheHill Hank Hill]] in Episode #184 "Bart Star".
* Creator/CarolKane:
** Maggie Simpson (uncredited) in Episode #20 "Bart vs. Thanksgiving".
** Blythe in Episode #736 "Step Brother from the Same Planet".
* Creator/MichaelKeaton: Jack Crowley in Episode #258 "Pokey Mom".
* Creator/EllieKemper: Mary Tannenbaum in Episode #694 "A Springfield Summer Christmas for Christmas".
* Creator/KeeganMichaelKey: Jazzy James in Episode #608-609 "The Great Phatsby".
* Creator/RichardKind: Director in Episode #694 "A Springfield Summer Christmas for Christmas".
* Creator/JoeyKing: Addy in Episode #683 "The Hateful Eight-Year-Olds".
* Creator/StephenKing: Himself in Episode #251 "Insane Clown Poppy".
* Creator/EarthaKitt: Herself (posthumously) in Episode #451 "Once Upon a Time in Springfield".
* Creator/JaneKrakowski: Zhenya in Episode #528 "The Fabulous Baker Boy".
* Creator/NickKroll: Lem in Episode #578 "Halloween of Horror".
* Creator/LisaKudrow: Alex Whitney in Episode #204 "Lard of the Dance".
* Music/LadyGaga: Herself in Episode #508 "Lisa Goes Gaga".
* Creator/PhilLaMarr:
** [[{{WesternAnimation/Futurama}} Hermes Conrad]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
** Auctioneer, Informed Party Guest in Episode #608-609 "The Great Phatsby".
* Creator/LisaLampanelli: Ramona in Episode #530 "Dangers on a Train".
* Creator/MartinLandau: The Great Raymondo in Episode #482 "The Great Simpsina".
* Creator/HughLaurie: Roger in Episode #468 "Treehouse of Horror XXI".
* Creator/LucyLawless: Herself in Episode #230 "Treehouse of Horror X".
* Creator/ClorisLeachman: Mrs. Glick in Episode #34 "Three Men and a Comic Book".
* Creator/NormanLear: Himself in Episode #626 "Mr. Lisa's Opus".
* Creator/StanLee: Himself in Episode #287 "I Am Furious (Yellow)", Episode #540 "Married to the Blob", and Episode #615 "Caper Chase".
* Creator/JaneLeeves: Edwina in Episode #317 "The Regina Monologues".
* Creator/JackLemmon: Frank Ormand in Episode #164 "The Twisted World of Marge Simpson".
* Creator/JayLeno: Himself in Episode #193 "The Last Temptation of Krust" and Episode #594 "To Courier with Love".
* Creator/DavidLetterman: Himself in Episode #497 "The D'oh-cial Network".
* Creator/JerryLewis: Professor John Frink Sr. in Episode #314 "Treehouse of Horror XIV".
* Creator/RichardLewis: Golem in Episode #382 "Treehouse of Horror XVII".
* Creator/DelroyLindo: Gabriel in Episode #276 "Brawl in the Family".
* Creator/RayLiotta: Morty Szyslak in Episode #634 "King Leer".
* Creator/JohnLithgow:
** Himself in Episode #659 "I'm Just a Girl Who Can't Say D'oh".
** Augustus Redfield in Episode #727 "Meat is Murder".
* Creator/LucyLiu: Madam Wu in Episode #347 "Goo Goo Gai Pan".
* Music/{{Lizzo}}: Goobie-Woo in Episode #750 "Homer's Adventures Through the Windshield Glass".
* Creator/ChristopherLloyd:
** [[Series/{{Taxi}} Jim Ignatowski]] in Episode #566 "My Fare Lady".
** [[Franchise/BackToTheFuture Emmett "Doc" Brown]] in ''Ride/TheSimpsonsRide''.
* Creator/EvaLongoria: Isabel Gutierrez in Episode #536 "The Kid is All Right".
* Creator/JuliaLouisDreyfus: Gloria in Episode #273 "A Hunka Hunka Burns in Love", Episode #404 "I Don't Wanna Know Why the Caged Bird Sings" and Episode #421 "Sex, Pies and Idiot Scrapes".
* Creator/RobLowe: Peter in #748 "The Very Hungry Caterpillars".
* Creator/PattiLuPone: Cheryl Monroe in Episode #651 "The Girl on the Bus".
* Creator/JaneLynch:
** Roz Davis in Episode #490 "Replaceable You".
** Jeanie in Episode #649 "Tis the 30th Season".
!!M-S
* Creator/SethMacFarlane: Ben in Episode #530 "Dangers on a Train".
* Creator/JohnMahoney: Dr. Robert Terwilliger, Sr. in Episode #408 "Funeral for a Fiend".
* Creator/{{Mako}}: Battling Seizure Robot in Episode #226 "Thirty Minutes Over Tokyo".
* Creator/GarryMarshall:
** Larry Kidkill in Episode #233 "Eight Misbehavin'".
** Sheldon Leavitt in Episode #476 "Homer the Father".
* Creator/PennyMarshall: Ms. Botz in Episode #13 "Some Enchanted Evening".
* Creator/AndreaMartin: Apu's Mother in Episode #185 "The Two Mrs. Nahasapeemapetilons".
* Creator/SteveMartin: Ray Patterson in Episode #200 "Trash of the Titans".
* Creator/KarenMaruyama: Dancing Woman in Episode #175 "In Marge We Trust" and Japanese Stewardess in Episode #226 "Thirty Minutes Over Tokyo".
* Creator/JackMcBrayer: Ewell Freestone in Episode #482 "The Great Simpsina".
* Creator/MelissaMcCarthy: Calvin in Episode #736 "Step Brother from the Same Planet".
* Music/PaulMcCartney: Himself in Episode #133 "Lisa The Vegetarian".
* Creator/FrancesMcDormand: Melanie Upfoot in Episode #375 "Girls Just Want to Have Sums".
* Creator/PatrickMcGoohan: [[Series/ThePrisoner1967 Number 6]] in Episode #254 "The Computer Wore Menace Shoes".
* Creator/MichaelMcKean:
** David St. Hubbins in Episode #57 "The Otto Show".
** Jerry Rude in Episode #224 "Monty Can't Buy Me Love".
* Creator/IanMcKellen: Himself in Episode #317 "The Regina Monologues".
* Creator/KateMcKinnon: Hettie Mae Boggs in Episode #588 "Gal of Constant Sorrow".
* Creator/EdMcMahon: Himself in Episode #207 "Treehouse of Horror IX".
* Creator/SamMcMurray:
** SNPP Employee/Duff Commercial VO in Episode #3 "Homer's Odyssey".
** Gulliver Dark in Episode #10 "Homer's Night Out".
* Creator/IanMcShane: Artemis in Episode #706 "The Last Barfighter".
* Creator/AudreyMeadows: Bea Simmons in Episode #30 "Old Money".
* Creator/ColmMeaney: Tom O'Flanagan in Episode #434 "In the Name of the Grandfather".
* Creator/StephenMerchant: CONRAD in Episode #584 "The Girl Code".
* Music/{{Metallica}}: Themselves in Episode #379 "The Mook, the Chef, the Wife and Her Homer".
* Creator/LeaMichele: Sarah in Episode #465 "Elementary School Musical".
* Creator/CristinMilioti: Barb in Episode #712 "A Serious Flanders".
* Creator/DanMintz: Tina Belcher in #642 "My Way or the Highway to Heaven".
* Creator/EugeneMirman: Gene Belcher in #642 "My Way or the Highway to Heaven".
* Creator/JayMohr: Creator/ChristopherWalken in Episode #251 "Insane Clown Poppy".
* Creator/CoryMonteith: Flynn in Episode #465 "Elementary School Musical".
* Creator/AlanMoore: Himself in Episode #407 "Husbands and Knives".
* Music/MandyMoore: Tabitha Vixx in Episode #378 "Marge and Homer Turn a Couple Play".
* Creator/MichaelMoore: Himself in Episode #316 "The President Wore Pearls".
* Creator/HarryMorgan: [[Series/{{Dragnet}} Bill Gannon]] in Episode #136 "Mother Simpson".
* Creator/ElisabethMoss: Gretchen in Episode #534 "Labor Pains".
* Creator/JohnMulaney: Warburton Parker in Episode #663 "The Winter of Our Monetized Content" and Episode #717 "The Longest Marge".
* Creator/MartinMull: Seth in Episode #209 "D'oh-in in the Wind".
* Creator/FrankieMuniz: Thelonius in Episode #266 "Trilogy of Error".
* UsefulNotes/RupertMurdoch: Himself in Episode #215 "Sunday, Cruddy Sunday".
* Creator/KumailNanjiani: Theo in Episode #720 "You Won't Believe What This Episode Is About – Act Three Will Shock You!"
* Creator/CharlesNapier:
** Warden in Episode #258 "Pokey Mom" and Episode #329 "The Wandering Juvie".
** Grant Conner in Episode #318 "The Fat and the Furriest".
** Officer Krackney in Episode #349 "The Seven-Beer Snitch".
* Creator/LiamNeeson: Father Sean in Episode #356 "The Father, the Son and the Holy Guest Star".
* Creator/SamNeill: Molloy in Episode #92 "Homer the Vigilante".
* Creator/BobNewhart: Himself in Episode #143 "Bart the Fink".
* Creator/PaulNewman: Himself in Episode #274 "The Blonder Years".
* Creator/NichelleNichols: Herself in Episode #332 "Simple Simpson".
* Creator/LeonardNimoy: Himself in Episode #71 "Marge vs. the Monorail" and Episode #163 "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]".
* Creator/EdwardNorton:
** Devon Bradley in Episode #255 "The Great Money Caper".
** Reverend Elijah Hooper in Episode #526 "Pulpit Friction".
* {{Music/NSYNC}}: Themselves in Episode #262 "New Kids on the Blecch".
* Music/TedNugent: Himself in Episode #404 "I Don't Wanna Know Why the Caged Bird Sings".
* Creator/ConanOBrien: Himself in Episode #93 "Bart Gets Famous".
* Creator/BobOdenkirk: Mob Lawyer in Episode #665 "The Fat Blue Line".
* Creator/ChrisODowd: Seamus in Episode #712 "A Serious Flanders".
* Creator/NickOfferman: Captain Bowditch in Episode #554 "The Wreck of the Relationship".
* Creator/KeithOlbermann: Himself in Episode #408 "Funeral for a Fiend".
* Creator/JohnOliver: Booth Wilkes-John in Episode #551 "Pay Pal".
* Creator/EdwardJamesOlmos: Pit Master in Episode #576 "Cue Detective".
* Creator/KaitlinOlson: Quinn Hopper in Episode #584 "The Girl Code".
* Creator/MaryKateAndAshleyOlsen: Themselves in Episode #323 "Diatribe of a Mad Housewife".
* Creator/TimothyOlyphant: Sheriff Flanders in Episode #712 "A Serious Flanders".
* Creator/PattonOswalt: T-Rex in Episode #515 "The Day the Earth Stood Cool".
* Creator/ElliotPage: Alaska Nebraska in Episode #439 "Waverly Hills 9-0-2-1-D'oh".
* Creator/MichaelPalin: Museum Curator in Episode #686 "I, Carumbus".
* Creator/JoePantoliano: Dante Calabresis in Episode #379 "The Mook, the Chef, the Wife and Her Homer".
* Creator/DonPardo: Himself in Episode #509 "Moonshine River".
* Creator/JessicaPare: Collette in Episode #712 "A Serious Flanders".
* Creator/NickPark: Himself in Episode #478 "Angry Dad: The Movie".
* Creator/ChrisParnell: Fiance in Episode #694 "A Springfield Summer Christmas for Christmas".
* Creator/MandyPatinkin: Hugh Parkfield in Episode #122 "Lisa's Wedding".
* Creator/JamesPatterson: Himself in Episode #392 "Yokel Chords".
* Creator/AaronPaul: [[Series/BreakingBad Jesse Pinkman]] ([[MediumBlending live action]]) in Episode #525 "What Animated Women Want" (CouchGag).
* Creator/PennAndTeller: Themselves in Episode #232 "Hello Gutter, Hello Fadder" and Episode #482 "The Great Simpsina".
* Creator/RheaPerlman: [[Series/{{Cheers}} Carla Tortelli]] in episode #114 "Fear of Flying".
* Creator/LukePerry: Himself in Episode #81 "Krusty Gets Kancelled".
* Music/KatyPerry: Herself ([[MediumBlending live action]]) in Episode #472 "The Fight Before Christmas".
* Creator/MatthewPerry: Ultrahouse's Matthew Perry voice in Episode #270 "Treehouse of Horror XII".
* Creator/MichellePfeiffer: Mindy Simmons in Episode #90 "The Last Temptation of Homer".
* Creator/DavidHydePierce:
** Cecil Terwilliger in Episode #169 "Brother from Another Series" and Episode #408 "Funeral for a Fiend".
** Himself in Episode #553 "Clown in the Dumps".
* Creator/BenPlatt: Blake in Episode #691 "Three Dreams Denied".
* Creator/AubreyPlaza: Amber Duffman in Episode #735 "From Beer to Paternity".
* Creator/GeorgePlimpton: Himself in Episode #303 "I'm Spelling as Fast as I Can".
* Creator/AmyPoehler: Jenda in Episode #350 "Future-Drama" and Episode #548 "Days of Future Future".
* Creator/BillyPorter: Desmond in Episode #679 "Highway to Well".
* Creator/NataliePortman: Darcy in Episode #390 "Little Big Girl" and Episode #509 "Moonshine River".
* Creator/BrianPosehn: Dumlee in Episode #614 "A Father's Watch".
* Creator/ParkerPosey: Becky in Episode #247 "It's a Mad, Mad, Mad, Mad Marge".
* Creator/TomPoston: Capital City Goofball in Episode #18 "Dancin' Homer".
* Creator/DanielRadcliffe:
** Edmund in Episode #468 "Treehouse of Horror XXI".
** Diggs in Episode #542 "Diggs".
** Himself in Episode #633 "No Good Read Goes Unpunished".
* Creator/MaryLynnRajskub: Chloe O'Brien in Episode #399 "24 Minutes".
* Creator/AndrewRannells: Himself in Episode #592 "How Lisa Got Her Marge Back".
* Music/RedHotChiliPeppers: Themselves in Episode #81 "Krusty Gets Kancelled".
* Creator/ChristinaRicci: Erin in Episode #153 "Summer of 4 ft. 2".
* Music/LionelRichie: Himself in Episode #401 "He Loves to Fly and He D'ohs".
* Creator/AmberRiley: Herself in Episode $465 "Elementary School Musical".
* Creator/KrystenRitter: Sheila Redfield in Episode #727 "Meat is Murder".
* Creator/JoanRivers: Annie Dubinsky in Episode #494 "The Ten-Per-Cent Solution".
* Creator/TimRobbins: Jim Hope in Episode #235 "Grift of the Magi".
* Creator/JohnRobertsActor: Linda Belcher in Episode #642 "My Way or the Highway to Heaven" and #734 "Treehouse of Horror XXXIII".
* Creator/SethRogen:
** Lyle [=McCarthy=] in Episode #442 "Homer the Whopper".
** Himself in Episode #539 "Steal This Episode".
* Creator/JustinRoiland: [[WesternAnimation/RickAndMorty Rick Sanchez and Morty Smith]] in Episode #574 "Mathlete's Feat" (CouchGag).
* Creator/AlRoker: Himself in Episode #509 "Moonshine River".
* Creator/RayRomano: Ray Magini in Episode #351 "Don't Fear the Roofer".
* Creator/MickeyRooney: Himself in Episode #130 "Radioactive Man".
* Creator/StephenRoot: Bildorf in Episode #697 "Wad Goals".
* Creator/AnikaNoniRose: Rita [=LaFleur=] in Episode #512 "Gone Abie Gone".
* Creator/JeffreyRoss: Jeff Ross in Episode #553 "Clown in the Dumps".
* Creator/IsabellaRossellini: Astrid Weller in Episode #222 "Mom and Pop Art".
* Creator/JKRowling: Herself in Episode #317 "The Regina Monologues".
* Creator/PaulRudd: Dr. Zander in Episode #481 "Love is a Many Strangled Thing".
* Creator/MayaRudolph: Julia in Episode #402 "Homer of Seville".
* {{Creator/Rupaul}}: Queen Chantein in Episode #646 "Werking Mom".
* Creator/MegRyan: Dr. Stacy Swanson in Episode #392 "Yokel Chords".
* Creator/WinonaRyder: Allison Taylor in Episode #105 "Lisa's Rival".
* Creator/KateySagal: [[{{WesternAnimation/Futurama}} Leela]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
* Creator/SusanSarandon: Ballet Teacher in Episode #120 "Homer vs. Patty and Selma".
* Creator/JenniferSaunders: Phoebe Pratt in Episode #616 "Looking for Mr. Goodbart".
* Creator/KristenSchaal:
** Taffy in Episode #484 "Homer Scissorhands".
** [[WesternAnimation/BobsBurgers Louise Belcher]] in Episode #642 "My Way or the Highway to Heaven".
* Creator/AmySchumer: Daphne Burns in Episode #597 "Monty Burns' Fleeing Circus".
* Creator/RyanSeacrest: Himself in Episode #464 "Judge Me Tender".
* Creator/GeorgeSegal: Nick in Episode #641 "Heartbreak Hotel".
* Creator/PeterSerafinowicz: CEO in Episode #647 "Krusty the Clown".
* Creator/AndySerkis: Cleanie in Episode #309 "Dude, Where's My Ranch?".
* Creator/AmandaSeyfried: Lori Spivak in Episode #761 "Frinkenstein's Monster".
* Creator/WallaceShawn: Wallace in Episode #655 "I Want You (She's So Heavy)".
* Creator/MartinSheen: Real Seymour Skinner in Episode #180 "The Principal and the Pauper".
* Creator/MichaelSheen: William Masters in Episode #612 "Kamp Krustier".
* Music/EdSheeran: Brendan Beiderbecke in Episode #628 "Haw-Haw Land".
* Creator/BrookeShields: Herself in Episode #78 "The Front".
* Creator/SabShimono:
** Master Chef in Episode #24 "One Fish, Two Fish, Blowfish, Blue Fish".
** Mr. Sparkle in Episode #175 "In Marge We Trust".
* Creator/MartinShort: Guthrie Frenel in Episode #620 "Springfield Splendor".
* Creator/JamesSie: The Lama in Episode #697 "Waf Goals".
* Creator/SarahSilverman:
** Nikki [=McKenna=] in Episode #456 "Stealing First Base" and Episode #509 "Moonshine River".
** Herself in Episode #553 "Clown in the Dumps".
** Rachel Cohen in Episode #600 "Treehouse of Horror XXVII".
* Music/SirMixALot: "Baby Likes Fat" singer in Episode #382 "Treehouse of Horror XVII".
* Creator/JKSimmons:
** [[Film/SpiderManTrilogy J. Jonah Jameson]] in Episode #384 "Moe'N'a Lisa".
** Tabloid Editor in Episode #394 "Homerazzi".
** J.J. Gruff in Episode #631 "3 Scenes Plus a Tag From a Marriage".
** Victor Kleskow in Episode #658 "Girl's in the Band".
* Creator/JennySlate: Piper Paisley in Episode #662 "Crystal Blue-Haired Persuasion".
* Creator/JohnSlattery: Robert Marlowe in Episode #493 "The Man in the Blue Flannel Pants".
* Music/SnoopDogg: Himself in Episode #608-609 "The Great Phatsby".
* Creator/SuzanneSomers: Herself in Episode #146 "The Day the Violence Died".
* Creator/RichSommer: Young Man in Episode #566 "My Fare Lady".
* Music/StephenSondheim: Himself in Episode #392 "Yokel Chords".
* Music/BritneySpears: Herself in Episode #238 "The Mansion Family".
* Creator/ArtSpiegelman: Himself in Episode #407 "Husbands and Knives".
* Creator/BrentSpiner: Robots in Episode #503 "Them, Robot".
* Creator/JerrySpringer: Himself in Episode #207 "Treehouse of Horror IX".
* Music/RingoStarr: Himself in Episode #31 "Brush with Greatness".
* Creator/RodSteiger: Captain Tenille in Episode #197 "Simpson Tide".
* Creator/DanielStern: Narrator in Episode #34 "Three Men and a Comic Book".
* Creator/FrancesSternhagen: Mrs. Bellamy in #290 "The Frying Game".
* Creator/JonStewart: Himself in Episode #410 "E Pluribus Wiggum".
* Creator/PatrickStewart: Number One in Episode #115 "Homer the Great".
** Vigorous Older Man in Episode #528 "The Fabulous Baker Boy".
* Creator/BenStiller: Garth Motherloving in Episode #277 "Sweets and Sour Marge".
* {{Music/Sting}}: Himself in Episode #48 "Radio Bart".
* Creator/MerylStreep: Jessica Lovejoy in Episode #110 "Bart's Girlfriend".
* Creator/CecilyStrong: Megan Matheson in Episode #630 "Homer is Where the Art Isn't."
* Creator/DonaldSutherland: Hollis Hurlbut in Episode #144 "List the Iconoclast".
* Creator/KieferSutherland:
** [[Series/TwentyFour Jack Bauer]] in Episode #399 "24 Minutes".
** Wayne Slater in Episode #487 "The Falcon and the D'ohman".
* Creator/WandaSykes: School Counselor in in Episode #525 "What Animated Women Want".
!!T-Z
* Creator/MrT: Himself in Episode #319 "Today I Am A Clown".
* Creator/GeorgeTakei:
** Akira in Episode #24 "One Fish, Two Fish, Blowfish, Blue Fish".
** Wink in Episode #226 "Thirty Minutes Over Tokyo".
** Sushi Chef in Episode #525 "What Animated Women Want".
** Himself in Episode #591 "The Burns Cage".
* Creator/AmyTan: Herself in Episode #251 "Insane Clown Poppy".
* Creator/ChanningTatum: Himself in Episode #539 "Steal This Episode".
* Creator/ElizabethTaylor:
** Maggie Simpson in Episode #69 "Lisa's First Word".
** Herself in Episode #81 "Krusty Gets Kancelled".
* Creator/RonTaylor: Bleeding Gums Murphy in Episode #6 "Moaning Lisa" and #125 "'Round Springfield".
* Creator/DavidTennant: Pa [=MacWeldon=] in Episode #758 "Ae Bonny Romance".
* Creator/DaveThomas:
** Rex Banner in Episode #171 "Homer Vs. The 18th Amendment".
** Bob Hope in Episode #370 "Bart Has Two Mommies".
* Creator/JonathanTaylorThomas: Luke Stetson in Episode #309 "Dude, Where's My Ranch?".
* Creator/LawrenceTierney: Don Brodka in Episode #139 "Marge Be Not Proud".
* Creator/JenniferTilly: Herself in Episode #512 "Gone Abie Gone".
* Creator/LaurenTom: [[{{WesternAnimation/Futurama}} Amy Wong]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
* Creator/MarisaTomei: Sara Sloane in Episode #304 "A Star is Born Again".
* Creator/LilyTomlin: Tammy in Episode #363 "The Last of the Red Hot Mamas".
* Creator/PaulFTompkins: Colby Redfield in Episode #727 "Meat Is Murder".
* Creator/KathleenTurner: Stacy Lovell in Episode #95 "Lisa Vs. Malibu Stacy".
* UsefulNotes/NeilDeGrasseTyson: Himself in Episode #615 "Caper Chase".
* Music/{{U2}}: Themselves in Episode #200 "Trash of the Titans".
* Creator/TraceyUllman: Emily Winthrop, Mrs. Winfield in Episode #29 "Bart's Dog Gets an F".
* Creator/JohnUpdike: Himself in Episode #251 "Insane Clown Poppy".
* Creator/DickVanDyke: Himself in Episode #753 "[=McMansion=] & Wife".[[note]]Van Dyke was 97 when he recorded his part, making him the oldest guest star in the show's history.[[/note]]
* Creator/CariceVanHouten: Annika Van Houten in Episode #572 "Let's Go Fly a Coot".
* Creator/JimVarney: Cooder in Episode #190 "Bart Carny".
* Creator/SofiaVergara: Carol Berrera in Episode #585 "Teenage Mutant Milk-Caused Hurdles".
* Creator/GoreVidal: Himself in Episode #384 "Moe'N'a Lisa".
* Creator/MaxVonSydow: Klaus Ziegler in Episode #545 "The War of Art".
* Creator/TaikaWaititi: Himself in Episode #759 "Murder, She Boat".
* Creator/BurtWard: {{ComicBook/Robin}} in Episode #295 "Large Marge".
* Creator/PendletonWard: "[[WesternAnimation/AdventureTime Simpsons Time]]" singer in Episode #597 "Monty Burns' Fleeing Circus" (CouchGag).
* Creator/JohnWaters: John in Episode #168 "Homer's Phobia".
* Creator/DennisWeaver: Buck [=McCoy=] in Episode #281 "The Lastest Gun in the West".
* Creator/StevenWeber: Neil in Episode #201 "King of the Hill".
* Music/TheWeeknd: Orion Hughes in Episode #721 "Bart the Cool Kid".
* Creator/RachelWeisz: Dr. Thurston in Episode #471 "How Munched is that Birdie in the Window?".
* Creator/AdamWest:
** Himself in Episode #68 "Mr. Plow".
** {{Series/Batman|1966}} in Episode #295 "Large Marge".
* Creator/BillyWest: [[{{WesternAnimation/Futurama}} Philip J. Fry, Professor Farnsworth, Dr. Zoidberg]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]" and ''VideoGame/TheSimpsonsGame''.
* Music/BarryWhite: Himself in Episode #79 "Whacking Day".
* Creator/BettyWhite: Herself in Episode #241 "Missionary: Impossible" and Episode #394 "Homerazzi".
* Creator/KristenWiig:
** Calliope Juniper in Episode #475 "Flaming Moe".
** Annie Crawford in Episode #531 "Homerland".
* Creator/FredWillard: Wally Kogen in Episode #215 "Sunday, Cruddy Sunday".
* Creator/AllisonWilliams: Candace's Friend in Episode #575 "Every Man's Dream".
* Music/PharrellWilliams: Himself in Episode #565 "Walking Big & Tall".
* Creator/TreatWilliams: Himself in Episode #505 "A Totally Fun Thing That Bart Will Never Do Again".
* Creator/PaulWinfield: Lucious Sweet in Episode #156 "The Homer They Fall" and #198 "The Trouble with Trillions".
* Creator/HenryWinkler: Ramrod in Episode #234 "Take My Wife, Sleaze".
* Creator/ReeseWitherspoon: Greta Wolfcastle in Episode #280 "The Bart Wants What It Wants".
* Creator/JamesWoods: Himself in Episode #94 "Homer and Apu".
* Creator/ZachWoods: Zane Furlong in Episode #674 "The Miseducation of Lisa Simpson".
* Creator/TomWolfe: Himself in in Episode #384 "Moe'N'a Lisa".
* Creator/WillWright: Himself in ''VideoGame/TheSimpsonsGame''.
* Creator/BowenYang: Richard in Episode #750 "Homer's Adventures Through the Windshield Glass".
* Music/WeirdAlYankovic: Himself in Episode #308 "Three Gays of the Condo" and #411 "That '90s Show" and #744 "Hostile Kirk Place".
* Creator/MichaelYork:
** Mason Fairbanks in Episode #366 "Homer's Paternity Coot".
** Dr. Lionel Budgie in Episode #589 "Lisa the Veterinarian", Episode #607 "Pork and Burns" and Episode #618 "Dogtown".
** Nigel in Episode #617 "Moho House".
* Creator/KeoneYoung: Sumo wrestler in Episode #226 "Thirty Minutes Over Tokyo".
[[/folder]]
!!Foreign Dubs
[[folder:Canadian French]]
* Creator/HugolinChevretteLandesque: Nelson Muntz (since Season 8).
* Creator/HubertGagnon: Homer Simpson (Seasons 1-27), Abraham "Abe" Simpson (Seasons 9-27), Herb Powell (first appearance only), and Creator/MelGibson ("[[Recap/TheSimpsonsS11E1BeyondBlunderdome Beyond Blunderdome]]").
* Creator/PascaleMontreuil: Colin in the movie.
* Creator/MartinWatier: Jimbo Jones, Dolph, Lou, and Rainier Wolfcastle, along with President Arnold Schwarzenegger in the movie.
* Creator/AlainZouvi: Waylon Smithers and Apu Nahasapeemapetilon (since "[[Recap/TheSimpsonsS9E8LisaTheSkeptic Lisa the Skeptic]]").
[[/folder]]
[[folder:European French]]
* Creator/VeroniqueAugereau: Marge Simpson / Patty bouvier / Selma Bouvier.
* Creator/NathalieBienaime: Bart Simpson (since Season 23) / Jimbo Jones.
* Creator/BrunoChoel: Alec Baldwin.
* Creator/GilbertLevy: Moe Szyslak / Lenny Leonard / Groundskeeper Willie / Professor Frink / Cletus Spuckler (since Season 3).
* Creator/PhilippePeythieu: Homer Jay Simpson / Abraham "Abe" Simpson / Otto Mann.
* Creator/AlexisVictor: Loki in ''WesternAnimation/TheGoodTheBartAndTheLoki''.
[[/folder]]
[[folder:German]]
* Creator/KaiTaschner: Professor Frink, Mr. Burns (since 2014).
[[/folder]]
[[folder:Hebrew]]
* Creator/ShiraNaor: Lisa Simpson, Maggie Simpson (movie).
* Creator/HadarShachafMaayan: Bart Simpson (movie).
* Creator/SharonShachal: Colin, Agnes Skinner, Cookie Kwan (movie).
[[/folder]]
[[folder:Hungarian]]
* Creator/IstvanBarath: Nelson Muntz.
[[/folder]]
[[folder:Italian]]
* Creator/ToninoAccolla: Homer Simpson (Seasons 1-23).
* Creator/NanniBaldini: Nelson Muntz (Seasons 4-15).
* Creator/OresteBaldini: Sideshow Mel (since Season 15).
* Creator/GaiaBolognesi: Bart Simpson (since Season 23).
* Creator/LiuBosisio: Marge Simpson (Seasons 1-22), Patty and Selma Bouvier (Seasons 1-21).
* Creator/MinoCaprio: Moe Szyslak (Seasons 1-7) and Abraham "Abe" Simpson (Season 23).
* Creator/MauraCenciarelli: Ralph Wiggum (since Season 10) and Rod Flanders.
* Creator/GilbertaCrispino: Martin Prince (since Season 14) and Todd Flanders.
* Creator/MarcoGuadagno: Nelson Muntz (Seasons 1-2).
* Creator/FrancescaGuadagno: Agnes Skinner (Seasons 22-29).
* Creator/IlariaLatini: Martin Prince in (Seasons 6-12) and Ralph Wiggum (Seasons 6-7).
* Creator/LauraLatini: Ralph Wiggum (Seasons 4-5).
* Creator/DavideLepore: Milhouse Van Houten.
* Creator/AngeloMaggi: Chief Wiggum (since Season 5).
* Creator/FabrizioMazzotta: Krusty the Clown.
* Creator/StellaMusy: Shauna Chalmers.
* Creator/IlariaStagni: Bart Simpson (Seasons 1-22).
* Creator/MonicaWard: Lisa Simpson.
[[/folder]]
[[folder:Japanese]]
'''NOTE:''' The following voice cast is from seasons 1 to 14 only. Starting with season 15, the entire voice cast was replaced with newer voice actors.
----
* Creator/ToruOhira: Homer Simpson until his death.
* Creator/TaekoKawata: Maggie Simpson in the TV series. In the theatrical version, Saori Seto voice her instead.
* Creator/NobuoTobita: Milhouse van Houten, Professor Frink, Jimbo Jones, Nick Riviera and Itchy. Creator/YuuSugimoto voiced Milhouse in the home video release of the movie.
* Creator/SayuriYamauchi: Scratchy.
* Creator/HiroyaIshimaru: Lionel Hutz and Duffman.
* Creator/ShigeruChiba: Otto Mann (seasons 1-6), Creator/ShinpachiTsuji (seasons 7-15).
* Creator/DaikiNakamura: Chief Wiggum and Dolph.
* Creator/JunpeiTakiguchi: Abraham "Abe" Simpson and Rabbi Hyman Krustofski until his death.
* Creator/BinShimada: Krusty, Troy [=McClure=], Rainier Wolfcastle (until season 11) and Mr. Sparkle.
* Creator/HiroshiIto: Kent Brockman, Kirk Van Houten, and Fat Tony (movie/theatrical version).
* Creator/MasashiHirose: Barney Gumble, Sideshow Mel and Apu.
* Creator/MinoruInaba: Moe Szyslak and Gil Gunderson.
* Creator/MitsuruOgata: Charles Montgomery Burns (second voice, TV series).
* Creator/VolcanoOta: Seymour Skinner (season 15 onwards)
* Creator/TakumiYamazaki: Arnie Pye.
* Creator/YokuShioya: Artie Ziff (season 1-?), Creator/HideyukiUmezu (?-15).
* Creator/RokuroNaya: Mayor Quimby. Creator/ShinpachiTsuji later replace him in further seasons.
* Creator/YuichiNagashima: Lenny.
* Creator/DaisukeGori: Judge Roy Snyder.
* Creator/KeiTomiyama: [[ShowWithinTheShow Jack]].
* Creator/ShinobuAdachi: Todd Flanders and Martin Prince.
* Creator/YosukeAkimoto: Principal Harlan Dondelinger.
* Creator/ToruFurusawa: Dean Bobby Peterson.
* Creator/JojiNakata: Reverend Lovejoy in the movie (theatrical version).[[note]]Very likely a CastingGag regarding his role as [[SinisterMinister Kirei Kotomine]] in ''VisualNovel/FateStayNight''[[/note]] In the home video version and the proper TV series, he is voiced regularly by Kousuke Meguro instead.
* Creator/MikiIto: Helen Lovejoy in the movie (theatrical version).[[note]]Just like with Nakata, this is very likely a CastingGag regarding her role as Taiga Fujimura in ''VisualNovel/FateStayNight'', through a very hilarious one considering Taiga is technically Kotomine's enemy due to the fact she is the step-sister of Shiro Emiya, his arch-enemy.([[/note]] In the home video version and the proper TV series, she is voiced regularly by Ai Satou instead.
* Creator/KikukoInoue: Collete in "[[Recap/TheSimpsonsS3E10FlamingMoes Flaming Moe's]]".
* Creator/KoichiYamadera: Leon Kompowsky in "[[Recap/TheSimpsonsS3E1StarkRavingDad Stark Raving Dad]]".
* Creator/RyuseiNakao: Mr. Bengstrom in "[[Recap/TheSimpsonsS2E19LisasSubstitute Lisa's Substitute]]".
* Creator/IkueOtani: Tobias in "[[Recap/TheSimpsonsS6E16BartVsAustralia Bart vs. Australia]]".
* Creator/MinamiTakayama: Adil Hoxha in "[[Recap/TheSimpsonsS1E11TheCrepesOfWrath The Crepes of Wrath]]".
* Creator/AkioOtsuka: Ringo Starr in "[[Recap/TheSimpsonsS2E18BrushWithGreatness Brush with Greatness]]".
* Creator/YasunoriMatsumoto: Cowboy Bob in "[[Recap/TheSimpsonsS1E7TheCallOfTheSimpsons The Call of the Simpsons]]".
* Creator/HochuOtsuka: Creator/MelGibson in "[[Recap/TheSimpsonsS11E1BeyondBlunderdome Beyond Blunderdome]]".
* Creator/KeikoToda and Morio Kazama: Dana Scully and Fox Mulder respectively in "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]", both actors reprising their roles from the Japanese dub of their [[Series/TheXFiles home series]].
* Creator/MichieTomizawa: Jessica Lovejoy in "[[Recap/TheSimpsonsS6E7BartsGirlfriend Bart's Girlfriend]]".
* Creator/RihokoYoshida: Mona Simpson in "[[Recap/TheSimpsonsS7E8MotherSimpson Mother Simpson]]".
* Creator/TakeshiAono: Herb Powell in "[[Recap/TheSimpsonsS2E15OhBrotherWhereArtThou Oh Brother, Where Art Thou?]]". Creator/KiyoyukiYanada voiced him in later episodes.
* Creator/AtsukoTanaka: Creator/BrookeShields in "[[Recap/TheSimpsonsS4E19TheFront The Front]]".
* Creator/EmiShinohara: Lurleen Lumpkin in "[[Recap/TheSimpsonsS3E20ColonelHomer Colonel Homer]]''.
* Creator/KumikoWatanabe: Princess Kashmir in "[[Recap/TheSimpsonsS1E10HomersNightOut Homer's Night Out]]".
* Creator/RikaFukami and Creator/KenyuuHoriuchi: Creator/KimBasinger and Creator/AlecBaldwin in "[[Recap/TheSimpsonsS10E5WhenYouDishUponAStar When You Dish Upon a Star]]".
* Creator/KenNarita: Jesse Grass in "[[Recap/TheSimpsonsS12E4LisaTheTreeHugger Lisa the Tree Hugger]]".
* Creator/YukoKobayashi: Mindy Simmons in "[[Recap/TheSimpsonsS5E9TheLastTemptationOfHomer The Last Temptation of Homer]]".
* Creator/MitsuruMiyamoto: Hugh Parkfield in "[[Recap/TheSimpsonsS6E19LisasWedding Lisa's Wedding]]".
* Creator/ReiIgarashi: Sara Sloane in "[[Recap/TheSimpsonsS14E13AStarIsBornAgain A Star is Born Again]]".
* Creator/KozoShioya: Larry Burns in "[[Recap/TheSimpsonsS8E4BurnsBabyBurns Burns, Baby Burns]]".
* Creator/NaokoMatsui: Samantha Stanky in "[[Recap/TheSimpsonsS3E23BartsFriendFallsInLove Bart's Friend Falls in Love]]".
* Creator/NaoyaUchida: Brother Faith in "[[Recap/TheSimpsonsS11E11FaithOff Faith Off]]".
* Creator/TesshoGenda: President Creator/ArnoldSchwarzenegger in the movie (both video and theatrical releases), this one a CastingGag around the fact he is the regular dub voice of him.
* Creator/TomomichiNishimura: Russ Cargill in the movie (theatrical release), while Creator/UnshoIshizuka voiced him in the home video version instead.
* Creator/UraraTakano: Mrs. Muntz in the movie (theatrical release)
* Creator/DaisukeHirakawa: Loki in ''WesternAnimation/TheGoodTheBartAndTheLoki'' (RoleReprise from the ''Franchise/MarvelCinematicUniverse'').
[[/folder]]
[[folder:European Spanish]]
* Creator/IsachaMengibar: Lisa Simpson.
* Creator/CheloMolina: Milhouse Van Houten.
* Creator/CheloVivares: Ralph Wiggum, Martin Prince, Itchy, Todd Flanders.
[[/folder]]
[[folder:Latin American Spanish]]
* Creator/PatriciaAcevedo: Lisa and Maggie Simpson until Season 15, and from season 31 onwards.
* Creator/RossyAguirre: Dolph in the first season, Allison Taylor in the sixth and Ms. Hoover in the tenth.
* Creator/YamilAtala: Cowboy Bob in "[[Recap/TheSimpsonsS1E7TheCallOfTheSimpsons The Call of the Simpsons]]".
* Creator/SalvadorDelgado: Lionel Hutz, Cecil Terwilliger, Troy [=McLure=] in season 7 and Mike Scoscia in "[[Recap/TheSimpsonsS3E17HomerAtTheBat Homer at the Bat]]".
* Creator/RocioGarcel: Lurleen Lumpkin in "[[Recap/TheSimpsonsS3E20ColonelHomer Colonel Homer]]".
* Creator/BlasGarcia: Arnold Schwarzenegger in ''WesternAnimation/TheSimpsonsMovie''.
* Creator/ReneGarcia: Artie Ziff in seasons 13 and 15, [[Music/{{Aerosmith}} Joe Perry]] in "[[Recap/TheSimpsonsS3E10FlamingMoes Flaming Moe's]]", Music/{{Sting}}, and Bill in seasons 3 and 10
* Creator/CristinaHernandez: Allison Taylor in the tenth season.
* Creator/CarlosInigo: Professor Frink from seasons 3 to 15 and Toshiro.
* Creator/JoseLavat: {{God}} in the tenth season.
* Creator/AraceliDeLeon: Rod Flanders in seasons 3,5 and 6. Creator/LilianaBarba voiced him from seasons 9 to 12.
* Creator/HermanLopez: Otto Mann from seasons 1 to 15.
* Creator/EdsonMatus: Nelson Muntz from seasons 16 to 17, Akira, Duffman, and Rainer Wolfcastle from season 25 onwards. Creator/EduardoGarza voiced him in season 8.
* Creator/RicardoMendoza: [[TheDanza Mendoza]] in "[[Recap/TheSimpsonsS2E15OhBrotherWhereArtThou Oh Brother, Where Art Thou?]]".
* Creator/ArturoMercado: Tom Hanks in ''WesternAnimation/TheSimpsonsMovie''
* Creator/AlfonsoObregonInclan: Cletus in seasons 11 and 12, [[Music/{{Aerosmith}} Joey Kramer]] in "[[Recap/TheSimpsonsS3E10FlamingMoes Flaming Moe's]]" and Creator/BobHope.
* Creator/GloriaObregon: Selma Bouvier.
* Creator/JoseLuisOrozco: Sideshow Bob in season 3, Leon Kompowsky, and Kent Brockman from season 32 onwards.
* Creator/MarianaOrtiz: Manjula since season 18 onwards.
* Creator/GabrielPingarron: Seymour Skinner from seasons 9 to 15.
* Creator/GerardoReyero: Reverend Lovejoy in seasons 7, 10 to 15, Jose Canseco in "[[Recap/TheSimpsonsS3E17HomerAtTheBat Homer at the Bat]]", and also Rainer Wolfcastle in season 7.
* Creator/BenjaminRivera: Jimbo Jones from seasons 2 to 14. Creator/CarlosInigo voiced Dolph from seasons 10 to 13.
* Creator/NallelySolis: Lisa Simpson, Milhouse Van Houten (since Season 16).
* Creator/MartinSoto: Mayor Joe Quimby from seasons 10 to 15.
* Creator/LauraTorres: Martin Prince, Kearney in the first season, Chuck, Scratchy in some episodes and Ralph Wiggum until Season 13. Creator/MarianaOrtiz, her later mother Creator/AraceliDeLeon and Creator/IsabelMartinon voiced Martin for some episodes.
* Creator/XochitlUgarte: Kumiko Albertson.
* Creator/GerardoVasquez: Doctor Hibbert in from season 10 to season 14, and from season 16 onwards. He was also Seymour Skinner and Barney Gumble from seasons 16 to 31.
* Creator/HumbertoVelez: Homer Simpson, [[Series/MarriedWithChildren Al Bundy]] in his brief cameo in "[[Recap/TheSimpsonsS4E20WhackingDay Whacking Day]]", and Creator/MattGroening until Season 15, then from season 31 onwards.
[[/folder]]
----
[[caption-width-right:350:The main cast. Not pictured: one of the most epic lists of guest stars in the history of television.]]
An index for the voice actors and voice actresses of ''WesternAnimation/TheSimpsons'' who have a page on TV Tropes.
----
[[foldercontrol]]
!!Series, Specials & Film
[[folder:Regular cast]]
!!Main cast
* Creator/DanCastellaneta: Homer Jay Simpson, Abraham "Abe" Jedediah Simpson II, Herschel "Krusty the Clown" Krustofski, Barney Gumble, Groundskeeper Willie, Mayor Joseph Quimby, Hans Moleman, Sideshow Mel, Gil Gunderson, Squeaky Voiced Teen, Kodos, Itchy.
* Creator/JulieKavner: Marjorie "Marge" Jacqueline Simpson (née Bouvier), Jacqueline Ingrid Bouvier (née Gurney), Patricia "Patty" Bouvier, Selma Bouvier.
* Creator/NancyCartwright: Bartholomew "Bart" Jo-Jo Simpson, Margaret "Maggie" Evelyn Simpson (later seasons), Ralph Wiggum, Nelson Muntz, Kearney, Todd Flanders, Ling Bouvier.
* Creator/YeardleySmith: Lisa Marie Simpson, Margaret "Maggie" Evelyn Simpson (earlier seasons).
* Creator/HankAzaria: Apu Nahasapeemapetilon, Morris "Moe" Szyslak, Carl Carlson (seasons 1-31), Chief Clarence "Clancy" Wiggum, Officer Lou (seasons 1-31), Jeffrey "Comic Book Guy" Albertson, Kirk Van Houten, Professor John Frink Jr., Superintendent Gary Chalmers, Cletus Spuckler, Snake Jailbird, Captain Horatio [=McCallister=], Bumblebee Man (seasons 4-31), Disco Stu, Dr. Nick Riviera, Duffman.
* Creator/HarryShearer: Nedward "Ned" Flanders, Charles "Monty" Montgomery Burns, Waylon J. Smithers Jr., Principal W. Seymour Skinner, Lenny Leonard, Kent Brockman, Reverend Timothy Lovejoy, Dr. Julius Hibbert (seasons 2-31), Judge Roy Snyder (seasons 1-31) Otto Man, Jasper Beardley, Rainier Wolfcastle, Kang, Scratchy.
!!Recurring cast
* Creator/SusanBlu: Various supporting characters in season 1.
* Creator/AlbertBrooks: Cowboy Bob, Jacques, Brad Goodman, Hank Scorpio, Tab Spangler, Russ Cargill, French Guy, Dr. Raufbold.
* Creator/KimberlyBrooks: Janey Powell, Lewis Clark (since season 32).
* Creator/GlennClose: Mona Simpson.
* Christopher Collins: Mr. Burns (season 1 only, replaced by Harry Shearer).
* Creator/GreyDeLisle: Sherri Mackleberry, Terri Mackleberry, Martin Prince, Üter Zörker (since season 31).
* Creator/AlexDesert: Carl Carlson, Officer Lou (since season 32).
* Chris Edgerly: Various supporting characters,.
* Marcia Mitzman Gaven: Replaced Maggie Roswell (seen below) for seasons 11-14.
* Creator/DanaGould: Himself, Murphy, Air Marshall, Barney Fife, Producer, Various.
* Creator/KelseyGrammer: Robert "Sideshow Bob" Terwilliger.
* Doris Grau: Lunchlady Doris (eventually replaced by Tress [=MacNeille=] after her death)
* Creator/PamelaHayden: Milhouse Van Houten, Jimbo Jones, Rod Flanders, Janey Powell, Sarah Wiggum.
* Jo Ann Harris: Various supporting characters (until season 4).
* Creator/PhilHartman: Lionel Hutz, Troy [=McClure=].
* Creator/JanHooks: Manjula Nahasapeemapetilon (replaced by Tress [=MacNeille=] after her death)
* Creator/JaneKaczmarek: Judge Constance Harm.
* Creator/MauriceLaMarche: Various supporting characters (since season 6).
* Creator/DawnnLewis: Berince Hibbert (since season 32).
* Creator/EricLopez: Bumblebee Man (since season 32)/Gambling Man/Lisa's Student.
* Creator/NatashaLyonne: Sophie (since season 28).
* Creator/TressMacNeille: Agnes Skinner, Lindsey Naegle, Brandine Spuckler, Crazy Cat Lady, Cookie Kwan, Bernice Hibbert, Manjula Nahasapeemapetilon, Lunchlady Doris, Dolph Starbeam, Kumiko Albertson (seasons 25-31).
* Creator/JoeMantegna: Fat Tony.
* Jackie Mason: Hyman Krustofsky.
* Creator/MeganMullally: Sarah Wiggum (since season 32).
* Creator/JayPharoah: Drederick Tatum (since season 33).
* Creator/PamelaReed: Ruth Powers.
* Creator/KevinMichaelRichardson: Dr. Julius Hibbert, Judge Roy Snyder (since season 32), Anger Watkins.
* Creator/AlexRocco: Roger Meyers Jr.
* Tony Rodriguez: Julio Franco (since season 32).
* Maggie Roswell: Elizabeth Hoover, Maude Flanders, Helen Lovejoy, Luann Van Houten, Mary Bailey, Princess Kashmir, Martha Quimby.
* Creator/RussiTaylor: Sherri Mackleberry, Terri Mackleberry, Martin Prince, Wendell Borton, Üter Zörker (until season 30)
* Creator/ScottThompson: Grady.
* Creator/MarciaWallace: Edna Krabappel.
* Creator/KerryWashington: Rayshelle Peyton.
* Karl Wiedergott: Various secondary characters (until season 22).
* Creator/FrankWelker: Santa's Little Helper, Snowball II, various animals.
* Creator/JennyYokobori: Kumiko Albertson (since season 32)
[[/folder]]
[[folder:Guest stars]]
!!A-F
* Music/FiftyCent: Himself in Episode #344 "Pranksta Rap".
* {{Music/Aerosmith}}: Themselves in Episode #45 "Flaming Moe's".
* Creator/ShohrehAghdashloo: Mina bin Laden in Episode #427 "Mypods and Broomsticks".
* Creator/JasonAlexander: Bourbon Verlander in Episode #615 "Caper Chase".
* Music/AlisonKraussAndUnionStation: They perform the theme song in Episode #500 "At Long Last Leave".
* Creator/SteveAllen:
** Electronically altered voice of Bart in Episode #53 "Separate Vocations".
** Himself in Episode #125 "'Round Springfield".
* Creator/UtkarshAmbudkar: Jay Nahasapeemapetilon in Episode #586 "Much Apu About Something".
* Creator/GillianAnderson: [[Series/TheXFiles Dana]] [[AgentScully Scully]] in Episode #163 "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]".
* Creator/AndreAgassi: Himself in Episode #260 "Tennis the Menace".
* Creator/JuddApatow: Himself in Episode #539 "Steal This Episode".
* Creator/FredArmisen: Terrence in Episode #515 "The Day the Earth Stood Cool" and #745 "Pin Gal".
* Creator/WillArnett: Deputy Director Gratman in Episode #539 "Steal This Episode".
* Creator/TomArnold: Himself in Episode #230 "Treehouse of Horror X".
* Creator/EdwardAsner: Newspaper editor in Episode #229 "Guess Who's Coming to Criticize Dinner?".
* Creator/DanAykroyd: Postage Stamp Fellow in Episode #695 "The Dad-Feelings Limited".
* Creator/DiedrichBader: Sheriff in Episode #245 "Kill the Alligator and Run".
* Creator/ScottBakula: Himself in Episode #672 "Bobby, It's Cold Outside".
* Creator/BobBalaban: Narrator in Episode #695 "The Dad-Feelings Limited".
* Creator/AlecBaldwin:
** Himself in Episode #208 "When You Dish Upon a Star".
** Caleb Thorn in Episode #357 "Bonfire of the Manatees".
* Creator/AnneBancroft: Dr. Zweig in Episode #114 "Fear of Flying".
* Creator/ElizabethBanks: Persephone Odair in Episode #754 "Thirst Trap: A Corporate Love Story".
* Creator/ChristineBaranski: Herself in Episode #714 "Portrait of a Lackey on Fire".
* Creator/SachaBaronCohen: Jakob in Episode #457 "The Greatest Story Ever D'ohed".
* Creator/DrewBarrymore: Sophie in Episode #251 "Insane Clown Poppy".
* Creator/AngelaBassett: [[UsefulNotes/BarackObama Michelle Obama]] in Episode #456 "Stealing First Base".
* Creator/MarioBatali: Himself in #491 "The Food Wife" and #622 "Treehouse of Horror XXVIII".
* Creator/JasonBateman: Himself in Episode #355 "Home Away from Homer".
* Creator/BryanBatt: Philip Hefflin/Carl in Episode #650 "Mad About the Toy".
* Creator/EdBegleyJr: Himself in Episode #216 "Homer to the Max" and #433 "Gone Maggie Gone".
* Creator/KristenBell: Harper Jambowski in Episode #580 "Friend with Benefit".
* Music/BelleAndSebastian: Themselves in Epsiode #758 "Ae Bonny Romance".
* Creator/HJonBenjamin: [[WesternAnimation/BobsBurgers Bob Belcher]] in Episode #642 "My Way or the Highway to Heaven".
* Music/TonyBennett: Himself in #18 "Dancin' Homer" and #294 "Bart vs. Lisa vs 3rd Grade" and #527 "Whiskey Business".
* Creator/GreggBerger: Various animals in Episode #471 "How Munched Is That Birdie in the Window?".
* Creator/HalleBerry: Herself in Episode #478 "Angry Dad: The Movie".
* Music/JustinBieber: Himself in Episode #528 "The Fabulous Faker Boy".
* Creator/JackBlack: Milo in Episode #407 "Husbands and Knives".
* UsefulNotes/TonyBlair: [[PoliticianGuestStar Himself]] in Episode #317 "The Regina Monologues".
* Creator/CateBlanchett: Elaine Wolff in Episode #684 "The Way of the Dog".
* Music/Blink182: Themselves in Episode #302 "Barting Over".
* Creator/RachelBloom: Annette in Episode #620 "Springfield Splendor".
* Creator/EmilyBlunt: Juliet Hobbes in Episode #429 "Lisa the Drama Queen".
* Creator/BobTheDragQueen: Herself in Episode #740 "My Life as a Vlog".
* Creator/PeterBogdanovich: Psychologist in Episode #392 "Yokel Chords".
* Creator/ErnestBorgnine: Himself in Episode #89 "Boy-Scoutz 'n the Hood".
* Creator/AnthonyBourdain: Himself in Episode #491 "The Food Wife".
* Creator/BillyBoyd: Himself in Episode #619 "The Serfsons".
* Creator/RussellBrand: Himself in Episode #478 "Angry Dad: The Movie".
* Creator/JamesLBrooks: [[CreatorCameo Himself]] in Episode #304 "A Star Is Born Again".
* Creator/MelBrooks: Himself in Episode #120 "Homer vs. Patty and Selma".
* Creator/PierceBrosnan: Ultrahouse's Pierce Brosnan voice and Himself in Episode #270 "Treehouse of Horror XII".
* Music/JamesBrown: Himself in Episode #88 "Bart's Inner Child".
* Creator/WrenTBrown: Virgil in Episode #454 "The Color Yellow".
* Creator/CarrieBrownstein: Emily in Episode #515 "The Day the Earth Stood Cool".
* Creator/HannibalBuress: Principal Finch in Episode #692 "The Road to Cincinnati"
* Creator/BillBurr: Townie, Man in Tunnel, Cart-Warning Man in Episode #599 "The Town".
* Creator/SteveBuscemi:
** Himself in Episode #311 "Brake My Wife, Please".
** Dwight David Diddlehoffer in Episode #404 "I Don't Wanna Know Why the Caged Bird Sings".
* Creator/GaryBusey: Himself in Episode #346 "On a Clear Day I Can't See My Sister".
* Music/DavidByrne: Himself in Episode #309 "Dude, Where's My Ranch?" and Episode #502 "How I Wet Your Mother".
* Creator/JamesCaan: Himself in Episode #337 "All's Fair in Oven War"
* Creator/NeveCampbell: Cassandra in Episode #448 "Rednecks and Broomsticks".
* Creator/LizzyCaplan: Virginia Johnson in Episode #612 "Kamp Krustier".
* Creator/SteveCarell: Dan Gillick in Episode #513 "Penny Wiseguys".
* Creator/DrewCarey: Himself in Episode #420 "All About Lisa".
* Creator/GeorgeCarlin: Munchie in Episode #209 "D'oh-in in the Wind".
* Music/JohnnyCash: Coyote in Episode #162 "The Mysterious Voyage of Homer".
* Creator/KimCattrall: Chloe Talbot in Episode #339 "She Used to Be My Girl".
* Creator/DickCavett: Himself in Episode #118 "Homie the Clown".
* Creator/MichaelCera: Nick in Episode #499 "The Daughter Also Rises".
* Creator/DonCheadle: Brother Faith in Episode #237 "Faith Off".
* Creator/CheechAndChong: Themselves in Episode #480 "A Midsummer's Nice Dream".
* Creator/MichaelChiklis: Handsome Boston quarterback in Episode #599 "The Town".
* Creator/TomClancy: Himself in Episode #323 "Diatribe of a Mad Housewife".
* Creator/DickClark: Himself in Episode #230 "Treehouse of Horror X".
* [[Music/FlightOfTheConchords Jermaine Clement]]: Ethan Ballantyne in Episode #465 "Elementary School Musical".
* Creator/StephenColbert: Colby Kraus in Episode #401 "He Loves to Fly and He D'ohs".
* Creator/GaryColeman: Himself in Episode #235 "Grift of the Magi", #250 "A Tale of Two Springfields", and #261 "Day of the Jackanapes".
* Creator/OliviaColman: Lily in Episode #689 "The 7 Beer Itch".
* Creator/TimConway: Himself in Episode #177 "The Simpsons Spin-off Showcase".
* Creator/SteveCoogan: Rowan Priddis in Episode #505 "A Totally Fun Thing That Bart Will Never Do Again".
* Creator/AndersonCooper: Himself in Episode #536 "The Kid Is All Right".
* Creator/BrianCox: Kostas Becker in Episode #712 "A Serious Flanders".
* Creator/BryanCranston:
** Stradivarius Cain in Episode #506 "The Spy Who Learned Me".
** [[Series/BreakingBad Walter White]] ([[MediumBlending live action]]) in Episode #525 "What Animated Women Want" (CouchGag).
* Music/DavidCrosby: Himself in Episode #80 "Marge in Chains" and Episode #82 "Homer's Barbershop Quartet".
* Creator/MarkCuban: Himself in Episode #428 "The Burns and the Bees".
* Creator/BenedictCumberbatch: British Prime Minister in Episode #520 "Love Is a Many-Splintered Thing".
* Creator/AlanCumming: Loki in Episode #708 "Bart's in Jail!".
* Creator/WillemDafoe:
** Commandent in Episode #178 "The Secret War of Lisa Simpson".
** Jack Lassen in Episode #559 "Blazed and Confused".
* Creator/AndyDaly: Judge Dowd in #632 "Fears of a Clown".
* Creator/RodneyDangerfield: Larry Burns in Episode #157 "Burns, Baby Burns".
* Creator/WilliamDaniels: KITT in Episode #205 "The Wizard of Evergreen Terrace".
* Creator/TedDanson: Sam Malone in Episode #114 "Fear of Flying".
* UsefulNotes/RichardDawkins: Himself in Episode #523 "Black Eyed, Please".
* Creator/EllenDeGeneres: Herself in Episode #464 "Judge Me Tender".
* Creator/GuillermoDelToro: Himself in Episode #654 "101 Mitigations".
* Creator/KatDennings: Valerie in Episode #626 "Mr. Lisa's Opus".
* Creator/EmilyDeschanel: Herself in Episode #640 "Bart's Not Dead".
* Creator/ZooeyDeschanel: Mary Spuckler in Episode #417 "Apocalypse Cow", Episode #509 "Moonshine River" and Episode #520 "Love is a Many-Splintered Thing".
* Creator/DannyDeVito: Herb Powell in Episode #28 "Oh Brother, Where Art Thou?", Episode #59 "Brother, Can You Spare Two Dimes?" and Episode #519 "The Changing of the Guardian".
* Creator/JohnDiMaggio: [[{{WesternAnimation/Futurama}} Bender]] in Episode #350 "Future-Drama", Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]", and ''VideoGame/TheSimpsonsGame''.
* Creator/AndyDick: Himself in Episode #392 "Yokel Chords".
* Creator/MattDillon: Louie in Episode #403 "Midnight Towboy".
* Music/DixieChicks: Themselves in Episode #416 "Papa Don't Leech".
* Creator/KirkDouglas: Chester J. Lampwick in Episode #146 "The Day the Violence Died".
* Creator/FranDrescher: Female Golem in Episode #382 "Treehouse of Horror XVII".
* Creator/AdamDriver: Adam Sackler in Episode #575 "Every Man's Dream".
* Creator/DavidDuchovny: [[Series/TheXFiles Fox]] [[AgentMulder Mulder]] in Episode #163 "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]".
* Creator/OlympiaDukakis: Zelda in Episode #282 "The Old Man and the Key".
* Creator/LenaDunham: Candace, Hannah Helene Horvath in Episode #575 "Every Man's Dream".
* Creator/BillyEichner: Billy in Episode #647 "Krusty the Clown" and #746 "Fan-ily Feud".
* Creator/HarlanEllison: Himself in Episode #540 "Married to the Blob".
* Creator/RobertEnglund: [[Franchise/ANightmareOnElmStreet Freddy Krueger]] in Episode #207 "Treehouse of Horror IX".
* Creator/RLeeErmey: Colonel Leslie Hapablap in Episode #137 "Sideshow Bob's Last Gleaming" and Episode #569 "Waiting for Duffman".
* Creator/MorganFairchild: Vivienne St. Charmaine in Episode #690 "Podcast News".
* Music/FallOutBoy: They perform the ending theme song in Episode #429 "Lisa the Drama Queen".
* Creator/AnnaFaris: Ashley in Episode #731 "Lisa the Boy Scout".
* Creator/TinaFey: Ms. Cantwell in Episode #523 "Black-Eyed, Please".
* Creator/NathanFielder: Doug Blattner in Episode #568 "Sky Police".
* Creator/HarveyFierstein: Karl in Episode #15 "Simpson and Delilah".
* Creator/FyvushFinkel: AsHimself playing Krusty in Episode #181 "Lisa's Sax".
* Creator/MiriamFlynn: Miss Barr in Episode #6 "Moaning Lisa".
* Creator/JaneFonda: Maxine Lombard in Episode #557 "Opposites A-Frack".
* Creator/JuneForay: Babysitting Lady in Episode #13 "Some Enchanted Evening".
* Creator/WillForte: King Toot in Episode #560 "Covercraft".
* Creator/JodieFoster: Maggie Simpson in Episode #440 "Four Great Women and a Manicure".
* Creator/BrendanFraser: Brad in Episode #201 "King of the Hill".
* Creator/StephenFry: Terrance in Episode #705 "The Man from G.R.A.M.P.A."
!!G-L
* Creator/GalGadot: Herself in Episode #640 "Bart's Not Dead".
* Creator/NeilGaiman:
** Himself in Episode #492 "The Book Job".
** Snowball II in Episode #622 "Treehouse of Horror XXVIII".
* Creator/ZachGalifianakis: Lucas Bortner in Episode #547 "Luca$".
* Creator/VictorGarber: Michael in Episode #714 "Portrait of a Lackey on Fire".
* Creator/AndyGarcia: Slick Publisher in Episode #492 "The Book Job".
* Creator/JaneaneGarofalo: Herself in Episode #193 "The Last Temptation of Krust" and Episode #494 "The Ten-Per-Cent Solution".
* Creator/SarahMichelleGellar: Gina Vendetti in Episode #329 "The Wandering Juvie" and Episode #509 "Moonshine River".
* Creator/BrianGeorge: [=MI5=] Agents in Episode #705 "The Man from G.R.A.M.P.A."
* Creator/RichardGere: Himself in Episode #275 "She of Little Faith".
* Creator/RickyGervais: Charles Heathbar in Episode #371 "Homer Simpson, This is Your Wife".
* Creator/MelGibson: Himself in Episode #227 "Beyond Blunderdome".
* Creator/KarenGillan: Maisie [=MacWeldon=] in Episode #758 "Ae Bonny Romance".
* Creator/JeffGoldblum: [=MacArthur=] Parker in Episode #147 "A Fish Called Selma".
* Creator/JohnGoodman: Meathook in Episode #234 "Take My Wife, Sleaze".
* UsefulNotes/DorisKearnsGoodwin: Herself in #599 "The Town".
* Creator/ElliottGould: Elliott Gould in Episode #299 "The Dad Who Knew Too Little".
* Creator/TopherGrace: Donny in Episode #413 "The Debarted".
* Creator/SethGreen: Mav Redfield in Episode #727 "Meat is Murder".
* Music/GreenDay: Themselves in ''WesternAnimation/TheSimpsonsMovie''.
* Creator/KathyGriffin: Francine in Episode #264 "Bye Bye Nerdie".
* Creator/MattGroening: [[CreatorCameo Himself]] in multiple episodes of the show, along with ''VideoGame/TheSimpsonsGame''.
* Creator/JonathanGroff: Actor Bart in Episode #640 "Bart's Not Dead".
* Creator/ChristopherGuest: Nigel Tufnel in Episode #57 "The Otto Show".
* Creator/BillHader:
** Slava in Episode #528 "The Fabulous Baker Boy".
** Manacek in Episode #630 "Homer is Where the Art Isn't."
* Creator/LarryHagman: Wallace Brady in Episode #377 "The Monkey Suit".
* Creator/MarkHamill: Himself, Leavelle, Theater Owner in Episode #212 "Mayored to the Mob".
* Creator/JonHamm: FBI Agent in Episode #473 "Donnie Fatso".
* Creator/ArmieHammer: Cameron Winklevoss, Tyler Winklevoss in Episode #497 "The D'oh-cial Network".
* Creator/TomHanks: Himself in ''WesternAnimation/TheSimpsonsMovie''.
* Creator/AlysonHannigan: Melody Juniper in Episode #475 "Flaming Moe".
* Creator/DavidHarbour: Fred Kranepool in Episode #685 "Undercover Burns".
* Creator/DanHarmon: Himself in Episode #620 "Springfield Splendor".
* Creator/JessHarnell: Various animals in Episode #271 "The Parent Rap".
* Creator/ValerieHarper:
** Proctor Perkins in Episode #518 "A Test Before Trying".
** Ms. Myles in Episode #626 "Mr. Lisa's Opus".
* Creator/WoodyHarrelson: Woody Boyd in Episode #114 "Fear of Flying".
* Creator/NeilPatrickHarris: Himself in Episode #39 "Bart the Murderer".
* Music/GeorgeHarrison: Himself in Episode #82 "Homer's Barbershop Quartet".
* Creator/AnneHathaway:
** Jenny in Episode #437 "The Good, the Sad and the Ugly" and Episode #509 "Moonshine River".
** Princess Penelope in Episode #451 "Once Upon a Time in Springfield".
* Creator/TonyHawk: Himself in Episode #302 "Barting Over".
* Creator/StephenHawking: Himself in Episode #225 "They Saved Lisa's Brain", Episode #351 "Don't Fear The Roofer", Episode #398 "Stop or My Dog Will Shoot!", and Episode #465 "Elementary School Musical".
* Creator/TarajiPHenson: Praline in Episode #608-609 "The Great Phatsby".
* Creator/DavidHerman: [[{{WesternAnimation/Futurama}} Scruffy]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
* Creator/DonHertzfeldt: "The Sampsans" in Episode #553 "Clown in the Dumps" (CouchGag).
* Creator/WernerHerzog: Walter Hotenhoffer in Episode #479 "The Scorpion's Tale".
* Creator/JonahHill: Andy Hamilton in Episode #447 "Pranks and Greens".
* Creator/DustinHoffman: Mr. Bergstrom in Episode #32 "Lisa's Substitute".
* Creator/BobHope: Himself in Episode #63 "Lisa the Beauty Queen".
* Creator/RonHoward: Himself in Episode #208 "When You Dish Upon a Star" and Episode #232 "Hello Gutter, Hello Fadder".
* Creator/HelenHunt: Renee in Episode #194 "Dumbell Indemnity".
* Creator/EricIdle: Declan Desmond in Episode #307 "Scuse Me While I Miss the Sky", Episode #340 "Fat Man and Little Boy", Episode #391 "Springfield Up" and Episode #506 "The Spy Who Learned Me".
* Creator/JeremyIrons: Bar Rag in Episode #498 "Moe Goes from Rags to Riches".
* Creator/SuzyEddieIzzard: Nigel Bakerbutcher in Episode #461 "To Surveil With Love".
* Creator/HughJackman: Janitor in Episode #728 "Poorhouse Rock".
* Creator/JoshuaJackson: Jesse Grass in Episode #252 "List the Tree Hugger".
* Music/MichaelJackson: Leon Kompowsky in Episode #36 "Stark Raving Dad".
* Creator/PeterJackson: Himself in Episode #754 "Thirst Trap: A Corporate Love Story".
* Music/MickJagger: Himself in Episode #293 "How I Spent My Strummer Vacation".
* UsefulNotes/LeBronJames: Himself in Episode #343 ""Homer and Ned's Hail Mary Pass".
* Creator/AllisonJanney: Julia in Episode #598 "Friends and Family".
* Music/EltonJohn: Himself in Episode #217 "I'm with Cupid".
* Creator/JamesEarlJones:
** Moving Man, Serak the Preparer, ''[[Creator/EdgarAllanPoe The Raven]]'' Narrator in Episode #16 "Treehouse of Horror".
** Alternate universe Maggie Simpson in Episode #109 "Treehouse of Horror V".
* Creator/RashidaJones: Portia in Episode #519 "The Changing of the Guardian".
* Music/TomJones: Himself in Episode #66 "Marge Gets a Job".
* Creator/MikeJudge: [[WesternAnimation/KingOfTheHill Hank Hill]] in Episode #184 "Bart Star".
* Creator/CarolKane:
** Maggie Simpson (uncredited) in Episode #20 "Bart vs. Thanksgiving".
** Blythe in Episode #736 "Step Brother from the Same Planet".
* Creator/MichaelKeaton: Jack Crowley in Episode #258 "Pokey Mom".
* Creator/EllieKemper: Mary Tannenbaum in Episode #694 "A Springfield Summer Christmas for Christmas".
* Creator/KeeganMichaelKey: Jazzy James in Episode #608-609 "The Great Phatsby".
* Creator/RichardKind: Director in Episode #694 "A Springfield Summer Christmas for Christmas".
* Creator/JoeyKing: Addy in Episode #683 "The Hateful Eight-Year-Olds".
* Creator/StephenKing: Himself in Episode #251 "Insane Clown Poppy".
* Creator/EarthaKitt: Herself (posthumously) in Episode #451 "Once Upon a Time in Springfield".
* Creator/JaneKrakowski: Zhenya in Episode #528 "The Fabulous Baker Boy".
* Creator/NickKroll: Lem in Episode #578 "Halloween of Horror".
* Creator/LisaKudrow: Alex Whitney in Episode #204 "Lard of the Dance".
* Music/LadyGaga: Herself in Episode #508 "Lisa Goes Gaga".
* Creator/PhilLaMarr:
** [[{{WesternAnimation/Futurama}} Hermes Conrad]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
** Auctioneer, Informed Party Guest in Episode #608-609 "The Great Phatsby".
* Creator/LisaLampanelli: Ramona in Episode #530 "Dangers on a Train".
* Creator/MartinLandau: The Great Raymondo in Episode #482 "The Great Simpsina".
* Creator/HughLaurie: Roger in Episode #468 "Treehouse of Horror XXI".
* Creator/LucyLawless: Herself in Episode #230 "Treehouse of Horror X".
* Creator/ClorisLeachman: Mrs. Glick in Episode #34 "Three Men and a Comic Book".
* Creator/NormanLear: Himself in Episode #626 "Mr. Lisa's Opus".
* Creator/StanLee: Himself in Episode #287 "I Am Furious (Yellow)", Episode #540 "Married to the Blob", and Episode #615 "Caper Chase".
* Creator/JaneLeeves: Edwina in Episode #317 "The Regina Monologues".
* Creator/JackLemmon: Frank Ormand in Episode #164 "The Twisted World of Marge Simpson".
* Creator/JayLeno: Himself in Episode #193 "The Last Temptation of Krust" and Episode #594 "To Courier with Love".
* Creator/DavidLetterman: Himself in Episode #497 "The D'oh-cial Network".
* Creator/JerryLewis: Professor John Frink Sr. in Episode #314 "Treehouse of Horror XIV".
* Creator/RichardLewis: Golem in Episode #382 "Treehouse of Horror XVII".
* Creator/DelroyLindo: Gabriel in Episode #276 "Brawl in the Family".
* Creator/RayLiotta: Morty Szyslak in Episode #634 "King Leer".
* Creator/JohnLithgow:
** Himself in Episode #659 "I'm Just a Girl Who Can't Say D'oh".
** Augustus Redfield in Episode #727 "Meat is Murder".
* Creator/LucyLiu: Madam Wu in Episode #347 "Goo Goo Gai Pan".
* Music/{{Lizzo}}: Goobie-Woo in Episode #750 "Homer's Adventures Through the Windshield Glass".
* Creator/ChristopherLloyd:
** [[Series/{{Taxi}} Jim Ignatowski]] in Episode #566 "My Fare Lady".
** [[Franchise/BackToTheFuture Emmett "Doc" Brown]] in ''Ride/TheSimpsonsRide''.
* Creator/EvaLongoria: Isabel Gutierrez in Episode #536 "The Kid is All Right".
* Creator/JuliaLouisDreyfus: Gloria in Episode #273 "A Hunka Hunka Burns in Love", Episode #404 "I Don't Wanna Know Why the Caged Bird Sings" and Episode #421 "Sex, Pies and Idiot Scrapes".
* Creator/RobLowe: Peter in #748 "The Very Hungry Caterpillars".
* Creator/PattiLuPone: Cheryl Monroe in Episode #651 "The Girl on the Bus".
* Creator/JaneLynch:
** Roz Davis in Episode #490 "Replaceable You".
** Jeanie in Episode #649 "Tis the 30th Season".
!!M-S
* Creator/SethMacFarlane: Ben in Episode #530 "Dangers on a Train".
* Creator/JohnMahoney: Dr. Robert Terwilliger, Sr. in Episode #408 "Funeral for a Fiend".
* Creator/{{Mako}}: Battling Seizure Robot in Episode #226 "Thirty Minutes Over Tokyo".
* Creator/GarryMarshall:
** Larry Kidkill in Episode #233 "Eight Misbehavin'".
** Sheldon Leavitt in Episode #476 "Homer the Father".
* Creator/PennyMarshall: Ms. Botz in Episode #13 "Some Enchanted Evening".
* Creator/AndreaMartin: Apu's Mother in Episode #185 "The Two Mrs. Nahasapeemapetilons".
* Creator/SteveMartin: Ray Patterson in Episode #200 "Trash of the Titans".
* Creator/KarenMaruyama: Dancing Woman in Episode #175 "In Marge We Trust" and Japanese Stewardess in Episode #226 "Thirty Minutes Over Tokyo".
* Creator/JackMcBrayer: Ewell Freestone in Episode #482 "The Great Simpsina".
* Creator/MelissaMcCarthy: Calvin in Episode #736 "Step Brother from the Same Planet".
* Music/PaulMcCartney: Himself in Episode #133 "Lisa The Vegetarian".
* Creator/FrancesMcDormand: Melanie Upfoot in Episode #375 "Girls Just Want to Have Sums".
* Creator/PatrickMcGoohan: [[Series/ThePrisoner1967 Number 6]] in Episode #254 "The Computer Wore Menace Shoes".
* Creator/MichaelMcKean:
** David St. Hubbins in Episode #57 "The Otto Show".
** Jerry Rude in Episode #224 "Monty Can't Buy Me Love".
* Creator/IanMcKellen: Himself in Episode #317 "The Regina Monologues".
* Creator/KateMcKinnon: Hettie Mae Boggs in Episode #588 "Gal of Constant Sorrow".
* Creator/EdMcMahon: Himself in Episode #207 "Treehouse of Horror IX".
* Creator/SamMcMurray:
** SNPP Employee/Duff Commercial VO in Episode #3 "Homer's Odyssey".
** Gulliver Dark in Episode #10 "Homer's Night Out".
* Creator/IanMcShane: Artemis in Episode #706 "The Last Barfighter".
* Creator/AudreyMeadows: Bea Simmons in Episode #30 "Old Money".
* Creator/ColmMeaney: Tom O'Flanagan in Episode #434 "In the Name of the Grandfather".
* Creator/StephenMerchant: CONRAD in Episode #584 "The Girl Code".
* Music/{{Metallica}}: Themselves in Episode #379 "The Mook, the Chef, the Wife and Her Homer".
* Creator/LeaMichele: Sarah in Episode #465 "Elementary School Musical".
* Creator/CristinMilioti: Barb in Episode #712 "A Serious Flanders".
* Creator/DanMintz: Tina Belcher in #642 "My Way or the Highway to Heaven".
* Creator/EugeneMirman: Gene Belcher in #642 "My Way or the Highway to Heaven".
* Creator/JayMohr: Creator/ChristopherWalken in Episode #251 "Insane Clown Poppy".
* Creator/CoryMonteith: Flynn in Episode #465 "Elementary School Musical".
* Creator/AlanMoore: Himself in Episode #407 "Husbands and Knives".
* Music/MandyMoore: Tabitha Vixx in Episode #378 "Marge and Homer Turn a Couple Play".
* Creator/MichaelMoore: Himself in Episode #316 "The President Wore Pearls".
* Creator/HarryMorgan: [[Series/{{Dragnet}} Bill Gannon]] in Episode #136 "Mother Simpson".
* Creator/ElisabethMoss: Gretchen in Episode #534 "Labor Pains".
* Creator/JohnMulaney: Warburton Parker in Episode #663 "The Winter of Our Monetized Content" and Episode #717 "The Longest Marge".
* Creator/MartinMull: Seth in Episode #209 "D'oh-in in the Wind".
* Creator/FrankieMuniz: Thelonius in Episode #266 "Trilogy of Error".
* UsefulNotes/RupertMurdoch: Himself in Episode #215 "Sunday, Cruddy Sunday".
* Creator/KumailNanjiani: Theo in Episode #720 "You Won't Believe What This Episode Is About – Act Three Will Shock You!"
* Creator/CharlesNapier:
** Warden in Episode #258 "Pokey Mom" and Episode #329 "The Wandering Juvie".
** Grant Conner in Episode #318 "The Fat and the Furriest".
** Officer Krackney in Episode #349 "The Seven-Beer Snitch".
* Creator/LiamNeeson: Father Sean in Episode #356 "The Father, the Son and the Holy Guest Star".
* Creator/SamNeill: Molloy in Episode #92 "Homer the Vigilante".
* Creator/BobNewhart: Himself in Episode #143 "Bart the Fink".
* Creator/PaulNewman: Himself in Episode #274 "The Blonder Years".
* Creator/NichelleNichols: Herself in Episode #332 "Simple Simpson".
* Creator/LeonardNimoy: Himself in Episode #71 "Marge vs. the Monorail" and Episode #163 "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]".
* Creator/EdwardNorton:
** Devon Bradley in Episode #255 "The Great Money Caper".
** Reverend Elijah Hooper in Episode #526 "Pulpit Friction".
* {{Music/NSYNC}}: Themselves in Episode #262 "New Kids on the Blecch".
* Music/TedNugent: Himself in Episode #404 "I Don't Wanna Know Why the Caged Bird Sings".
* Creator/ConanOBrien: Himself in Episode #93 "Bart Gets Famous".
* Creator/BobOdenkirk: Mob Lawyer in Episode #665 "The Fat Blue Line".
* Creator/ChrisODowd: Seamus in Episode #712 "A Serious Flanders".
* Creator/NickOfferman: Captain Bowditch in Episode #554 "The Wreck of the Relationship".
* Creator/KeithOlbermann: Himself in Episode #408 "Funeral for a Fiend".
* Creator/JohnOliver: Booth Wilkes-John in Episode #551 "Pay Pal".
* Creator/EdwardJamesOlmos: Pit Master in Episode #576 "Cue Detective".
* Creator/KaitlinOlson: Quinn Hopper in Episode #584 "The Girl Code".
* Creator/MaryKateAndAshleyOlsen: Themselves in Episode #323 "Diatribe of a Mad Housewife".
* Creator/TimothyOlyphant: Sheriff Flanders in Episode #712 "A Serious Flanders".
* Creator/PattonOswalt: T-Rex in Episode #515 "The Day the Earth Stood Cool".
* Creator/ElliotPage: Alaska Nebraska in Episode #439 "Waverly Hills 9-0-2-1-D'oh".
* Creator/MichaelPalin: Museum Curator in Episode #686 "I, Carumbus".
* Creator/JoePantoliano: Dante Calabresis in Episode #379 "The Mook, the Chef, the Wife and Her Homer".
* Creator/DonPardo: Himself in Episode #509 "Moonshine River".
* Creator/JessicaPare: Collette in Episode #712 "A Serious Flanders".
* Creator/NickPark: Himself in Episode #478 "Angry Dad: The Movie".
* Creator/ChrisParnell: Fiance in Episode #694 "A Springfield Summer Christmas for Christmas".
* Creator/MandyPatinkin: Hugh Parkfield in Episode #122 "Lisa's Wedding".
* Creator/JamesPatterson: Himself in Episode #392 "Yokel Chords".
* Creator/AaronPaul: [[Series/BreakingBad Jesse Pinkman]] ([[MediumBlending live action]]) in Episode #525 "What Animated Women Want" (CouchGag).
* Creator/PennAndTeller: Themselves in Episode #232 "Hello Gutter, Hello Fadder" and Episode #482 "The Great Simpsina".
* Creator/RheaPerlman: [[Series/{{Cheers}} Carla Tortelli]] in episode #114 "Fear of Flying".
* Creator/LukePerry: Himself in Episode #81 "Krusty Gets Kancelled".
* Music/KatyPerry: Herself ([[MediumBlending live action]]) in Episode #472 "The Fight Before Christmas".
* Creator/MatthewPerry: Ultrahouse's Matthew Perry voice in Episode #270 "Treehouse of Horror XII".
* Creator/MichellePfeiffer: Mindy Simmons in Episode #90 "The Last Temptation of Homer".
* Creator/DavidHydePierce:
** Cecil Terwilliger in Episode #169 "Brother from Another Series" and Episode #408 "Funeral for a Fiend".
** Himself in Episode #553 "Clown in the Dumps".
* Creator/BenPlatt: Blake in Episode #691 "Three Dreams Denied".
* Creator/AubreyPlaza: Amber Duffman in Episode #735 "From Beer to Paternity".
* Creator/GeorgePlimpton: Himself in Episode #303 "I'm Spelling as Fast as I Can".
* Creator/AmyPoehler: Jenda in Episode #350 "Future-Drama" and Episode #548 "Days of Future Future".
* Creator/BillyPorter: Desmond in Episode #679 "Highway to Well".
* Creator/NataliePortman: Darcy in Episode #390 "Little Big Girl" and Episode #509 "Moonshine River".
* Creator/BrianPosehn: Dumlee in Episode #614 "A Father's Watch".
* Creator/ParkerPosey: Becky in Episode #247 "It's a Mad, Mad, Mad, Mad Marge".
* Creator/TomPoston: Capital City Goofball in Episode #18 "Dancin' Homer".
* Creator/DanielRadcliffe:
** Edmund in Episode #468 "Treehouse of Horror XXI".
** Diggs in Episode #542 "Diggs".
** Himself in Episode #633 "No Good Read Goes Unpunished".
* Creator/MaryLynnRajskub: Chloe O'Brien in Episode #399 "24 Minutes".
* Creator/AndrewRannells: Himself in Episode #592 "How Lisa Got Her Marge Back".
* Music/RedHotChiliPeppers: Themselves in Episode #81 "Krusty Gets Kancelled".
* Creator/ChristinaRicci: Erin in Episode #153 "Summer of 4 ft. 2".
* Music/LionelRichie: Himself in Episode #401 "He Loves to Fly and He D'ohs".
* Creator/AmberRiley: Herself in Episode $465 "Elementary School Musical".
* Creator/KrystenRitter: Sheila Redfield in Episode #727 "Meat is Murder".
* Creator/JoanRivers: Annie Dubinsky in Episode #494 "The Ten-Per-Cent Solution".
* Creator/TimRobbins: Jim Hope in Episode #235 "Grift of the Magi".
* Creator/JohnRobertsActor: Linda Belcher in Episode #642 "My Way or the Highway to Heaven" and #734 "Treehouse of Horror XXXIII".
* Creator/SethRogen:
** Lyle [=McCarthy=] in Episode #442 "Homer the Whopper".
** Himself in Episode #539 "Steal This Episode".
* Creator/JustinRoiland: [[WesternAnimation/RickAndMorty Rick Sanchez and Morty Smith]] in Episode #574 "Mathlete's Feat" (CouchGag).
* Creator/AlRoker: Himself in Episode #509 "Moonshine River".
* Creator/RayRomano: Ray Magini in Episode #351 "Don't Fear the Roofer".
* Creator/MickeyRooney: Himself in Episode #130 "Radioactive Man".
* Creator/StephenRoot: Bildorf in Episode #697 "Wad Goals".
* Creator/AnikaNoniRose: Rita [=LaFleur=] in Episode #512 "Gone Abie Gone".
* Creator/JeffreyRoss: Jeff Ross in Episode #553 "Clown in the Dumps".
* Creator/IsabellaRossellini: Astrid Weller in Episode #222 "Mom and Pop Art".
* Creator/JKRowling: Herself in Episode #317 "The Regina Monologues".
* Creator/PaulRudd: Dr. Zander in Episode #481 "Love is a Many Strangled Thing".
* Creator/MayaRudolph: Julia in Episode #402 "Homer of Seville".
* {{Creator/Rupaul}}: Queen Chantein in Episode #646 "Werking Mom".
* Creator/MegRyan: Dr. Stacy Swanson in Episode #392 "Yokel Chords".
* Creator/WinonaRyder: Allison Taylor in Episode #105 "Lisa's Rival".
* Creator/KateySagal: [[{{WesternAnimation/Futurama}} Leela]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
* Creator/SusanSarandon: Ballet Teacher in Episode #120 "Homer vs. Patty and Selma".
* Creator/JenniferSaunders: Phoebe Pratt in Episode #616 "Looking for Mr. Goodbart".
* Creator/KristenSchaal:
** Taffy in Episode #484 "Homer Scissorhands".
** [[WesternAnimation/BobsBurgers Louise Belcher]] in Episode #642 "My Way or the Highway to Heaven".
* Creator/AmySchumer: Daphne Burns in Episode #597 "Monty Burns' Fleeing Circus".
* Creator/RyanSeacrest: Himself in Episode #464 "Judge Me Tender".
* Creator/GeorgeSegal: Nick in Episode #641 "Heartbreak Hotel".
* Creator/PeterSerafinowicz: CEO in Episode #647 "Krusty the Clown".
* Creator/AndySerkis: Cleanie in Episode #309 "Dude, Where's My Ranch?".
* Creator/AmandaSeyfried: Lori Spivak in Episode #761 "Frinkenstein's Monster".
* Creator/WallaceShawn: Wallace in Episode #655 "I Want You (She's So Heavy)".
* Creator/MartinSheen: Real Seymour Skinner in Episode #180 "The Principal and the Pauper".
* Creator/MichaelSheen: William Masters in Episode #612 "Kamp Krustier".
* Music/EdSheeran: Brendan Beiderbecke in Episode #628 "Haw-Haw Land".
* Creator/BrookeShields: Herself in Episode #78 "The Front".
* Creator/SabShimono:
** Master Chef in Episode #24 "One Fish, Two Fish, Blowfish, Blue Fish".
** Mr. Sparkle in Episode #175 "In Marge We Trust".
* Creator/MartinShort: Guthrie Frenel in Episode #620 "Springfield Splendor".
* Creator/JamesSie: The Lama in Episode #697 "Waf Goals".
* Creator/SarahSilverman:
** Nikki [=McKenna=] in Episode #456 "Stealing First Base" and Episode #509 "Moonshine River".
** Herself in Episode #553 "Clown in the Dumps".
** Rachel Cohen in Episode #600 "Treehouse of Horror XXVII".
* Music/SirMixALot: "Baby Likes Fat" singer in Episode #382 "Treehouse of Horror XVII".
* Creator/JKSimmons:
** [[Film/SpiderManTrilogy J. Jonah Jameson]] in Episode #384 "Moe'N'a Lisa".
** Tabloid Editor in Episode #394 "Homerazzi".
** J.J. Gruff in Episode #631 "3 Scenes Plus a Tag From a Marriage".
** Victor Kleskow in Episode #658 "Girl's in the Band".
* Creator/JennySlate: Piper Paisley in Episode #662 "Crystal Blue-Haired Persuasion".
* Creator/JohnSlattery: Robert Marlowe in Episode #493 "The Man in the Blue Flannel Pants".
* Music/SnoopDogg: Himself in Episode #608-609 "The Great Phatsby".
* Creator/SuzanneSomers: Herself in Episode #146 "The Day the Violence Died".
* Creator/RichSommer: Young Man in Episode #566 "My Fare Lady".
* Music/StephenSondheim: Himself in Episode #392 "Yokel Chords".
* Music/BritneySpears: Herself in Episode #238 "The Mansion Family".
* Creator/ArtSpiegelman: Himself in Episode #407 "Husbands and Knives".
* Creator/BrentSpiner: Robots in Episode #503 "Them, Robot".
* Creator/JerrySpringer: Himself in Episode #207 "Treehouse of Horror IX".
* Music/RingoStarr: Himself in Episode #31 "Brush with Greatness".
* Creator/RodSteiger: Captain Tenille in Episode #197 "Simpson Tide".
* Creator/DanielStern: Narrator in Episode #34 "Three Men and a Comic Book".
* Creator/FrancesSternhagen: Mrs. Bellamy in #290 "The Frying Game".
* Creator/JonStewart: Himself in Episode #410 "E Pluribus Wiggum".
* Creator/PatrickStewart: Number One in Episode #115 "Homer the Great".
** Vigorous Older Man in Episode #528 "The Fabulous Baker Boy".
* Creator/BenStiller: Garth Motherloving in Episode #277 "Sweets and Sour Marge".
* {{Music/Sting}}: Himself in Episode #48 "Radio Bart".
* Creator/MerylStreep: Jessica Lovejoy in Episode #110 "Bart's Girlfriend".
* Creator/CecilyStrong: Megan Matheson in Episode #630 "Homer is Where the Art Isn't."
* Creator/DonaldSutherland: Hollis Hurlbut in Episode #144 "List the Iconoclast".
* Creator/KieferSutherland:
** [[Series/TwentyFour Jack Bauer]] in Episode #399 "24 Minutes".
** Wayne Slater in Episode #487 "The Falcon and the D'ohman".
* Creator/WandaSykes: School Counselor in in Episode #525 "What Animated Women Want".
!!T-Z
* Creator/MrT: Himself in Episode #319 "Today I Am A Clown".
* Creator/GeorgeTakei:
** Akira in Episode #24 "One Fish, Two Fish, Blowfish, Blue Fish".
** Wink in Episode #226 "Thirty Minutes Over Tokyo".
** Sushi Chef in Episode #525 "What Animated Women Want".
** Himself in Episode #591 "The Burns Cage".
* Creator/AmyTan: Herself in Episode #251 "Insane Clown Poppy".
* Creator/ChanningTatum: Himself in Episode #539 "Steal This Episode".
* Creator/ElizabethTaylor:
** Maggie Simpson in Episode #69 "Lisa's First Word".
** Herself in Episode #81 "Krusty Gets Kancelled".
* Creator/RonTaylor: Bleeding Gums Murphy in Episode #6 "Moaning Lisa" and #125 "'Round Springfield".
* Creator/DavidTennant: Pa [=MacWeldon=] in Episode #758 "Ae Bonny Romance".
* Creator/DaveThomas:
** Rex Banner in Episode #171 "Homer Vs. The 18th Amendment".
** Bob Hope in Episode #370 "Bart Has Two Mommies".
* Creator/JonathanTaylorThomas: Luke Stetson in Episode #309 "Dude, Where's My Ranch?".
* Creator/LawrenceTierney: Don Brodka in Episode #139 "Marge Be Not Proud".
* Creator/JenniferTilly: Herself in Episode #512 "Gone Abie Gone".
* Creator/LaurenTom: [[{{WesternAnimation/Futurama}} Amy Wong]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]".
* Creator/MarisaTomei: Sara Sloane in Episode #304 "A Star is Born Again".
* Creator/LilyTomlin: Tammy in Episode #363 "The Last of the Red Hot Mamas".
* Creator/PaulFTompkins: Colby Redfield in Episode #727 "Meat Is Murder".
* Creator/KathleenTurner: Stacy Lovell in Episode #95 "Lisa Vs. Malibu Stacy".
* UsefulNotes/NeilDeGrasseTyson: Himself in Episode #615 "Caper Chase".
* Music/{{U2}}: Themselves in Episode #200 "Trash of the Titans".
* Creator/TraceyUllman: Emily Winthrop, Mrs. Winfield in Episode #29 "Bart's Dog Gets an F".
* Creator/JohnUpdike: Himself in Episode #251 "Insane Clown Poppy".
* Creator/DickVanDyke: Himself in Episode #753 "[=McMansion=] & Wife".[[note]]Van Dyke was 97 when he recorded his part, making him the oldest guest star in the show's history.[[/note]]
* Creator/CariceVanHouten: Annika Van Houten in Episode #572 "Let's Go Fly a Coot".
* Creator/JimVarney: Cooder in Episode #190 "Bart Carny".
* Creator/SofiaVergara: Carol Berrera in Episode #585 "Teenage Mutant Milk-Caused Hurdles".
* Creator/GoreVidal: Himself in Episode #384 "Moe'N'a Lisa".
* Creator/MaxVonSydow: Klaus Ziegler in Episode #545 "The War of Art".
* Creator/TaikaWaititi: Himself in Episode #759 "Murder, She Boat".
* Creator/BurtWard: {{ComicBook/Robin}} in Episode #295 "Large Marge".
* Creator/PendletonWard: "[[WesternAnimation/AdventureTime Simpsons Time]]" singer in Episode #597 "Monty Burns' Fleeing Circus" (CouchGag).
* Creator/JohnWaters: John in Episode #168 "Homer's Phobia".
* Creator/DennisWeaver: Buck [=McCoy=] in Episode #281 "The Lastest Gun in the West".
* Creator/StevenWeber: Neil in Episode #201 "King of the Hill".
* Music/TheWeeknd: Orion Hughes in Episode #721 "Bart the Cool Kid".
* Creator/RachelWeisz: Dr. Thurston in Episode #471 "How Munched is that Birdie in the Window?".
* Creator/AdamWest:
** Himself in Episode #68 "Mr. Plow".
** {{Series/Batman|1966}} in Episode #295 "Large Marge".
* Creator/BillyWest: [[{{WesternAnimation/Futurama}} Philip J. Fry, Professor Farnsworth, Dr. Zoidberg]] in Episode #558 "[[Recap/TheSimpsonsS26E6Simpsorama Simpsorama]]" and ''VideoGame/TheSimpsonsGame''.
* Music/BarryWhite: Himself in Episode #79 "Whacking Day".
* Creator/BettyWhite: Herself in Episode #241 "Missionary: Impossible" and Episode #394 "Homerazzi".
* Creator/KristenWiig:
** Calliope Juniper in Episode #475 "Flaming Moe".
** Annie Crawford in Episode #531 "Homerland".
* Creator/FredWillard: Wally Kogen in Episode #215 "Sunday, Cruddy Sunday".
* Creator/AllisonWilliams: Candace's Friend in Episode #575 "Every Man's Dream".
* Music/PharrellWilliams: Himself in Episode #565 "Walking Big & Tall".
* Creator/TreatWilliams: Himself in Episode #505 "A Totally Fun Thing That Bart Will Never Do Again".
* Creator/PaulWinfield: Lucious Sweet in Episode #156 "The Homer They Fall" and #198 "The Trouble with Trillions".
* Creator/HenryWinkler: Ramrod in Episode #234 "Take My Wife, Sleaze".
* Creator/ReeseWitherspoon: Greta Wolfcastle in Episode #280 "The Bart Wants What It Wants".
* Creator/JamesWoods: Himself in Episode #94 "Homer and Apu".
* Creator/ZachWoods: Zane Furlong in Episode #674 "The Miseducation of Lisa Simpson".
* Creator/TomWolfe: Himself in in Episode #384 "Moe'N'a Lisa".
* Creator/WillWright: Himself in ''VideoGame/TheSimpsonsGame''.
* Creator/BowenYang: Richard in Episode #750 "Homer's Adventures Through the Windshield Glass".
* Music/WeirdAlYankovic: Himself in Episode #308 "Three Gays of the Condo" and #411 "That '90s Show" and #744 "Hostile Kirk Place".
* Creator/MichaelYork:
** Mason Fairbanks in Episode #366 "Homer's Paternity Coot".
** Dr. Lionel Budgie in Episode #589 "Lisa the Veterinarian", Episode #607 "Pork and Burns" and Episode #618 "Dogtown".
** Nigel in Episode #617 "Moho House".
* Creator/KeoneYoung: Sumo wrestler in Episode #226 "Thirty Minutes Over Tokyo".
[[/folder]]
!!Foreign Dubs
[[folder:Canadian French]]
* Creator/HugolinChevretteLandesque: Nelson Muntz (since Season 8).
* Creator/HubertGagnon: Homer Simpson (Seasons 1-27), Abraham "Abe" Simpson (Seasons 9-27), Herb Powell (first appearance only), and Creator/MelGibson ("[[Recap/TheSimpsonsS11E1BeyondBlunderdome Beyond Blunderdome]]").
* Creator/PascaleMontreuil: Colin in the movie.
* Creator/MartinWatier: Jimbo Jones, Dolph, Lou, and Rainier Wolfcastle, along with President Arnold Schwarzenegger in the movie.
* Creator/AlainZouvi: Waylon Smithers and Apu Nahasapeemapetilon (since "[[Recap/TheSimpsonsS9E8LisaTheSkeptic Lisa the Skeptic]]").
[[/folder]]
[[folder:European French]]
* Creator/VeroniqueAugereau: Marge Simpson / Patty bouvier / Selma Bouvier.
* Creator/NathalieBienaime: Bart Simpson (since Season 23) / Jimbo Jones.
* Creator/BrunoChoel: Alec Baldwin.
* Creator/GilbertLevy: Moe Szyslak / Lenny Leonard / Groundskeeper Willie / Professor Frink / Cletus Spuckler (since Season 3).
* Creator/PhilippePeythieu: Homer Jay Simpson / Abraham "Abe" Simpson / Otto Mann.
* Creator/AlexisVictor: Loki in ''WesternAnimation/TheGoodTheBartAndTheLoki''.
[[/folder]]
[[folder:German]]
* Creator/KaiTaschner: Professor Frink, Mr. Burns (since 2014).
[[/folder]]
[[folder:Hebrew]]
* Creator/ShiraNaor: Lisa Simpson, Maggie Simpson (movie).
* Creator/HadarShachafMaayan: Bart Simpson (movie).
* Creator/SharonShachal: Colin, Agnes Skinner, Cookie Kwan (movie).
[[/folder]]
[[folder:Hungarian]]
* Creator/IstvanBarath: Nelson Muntz.
[[/folder]]
[[folder:Italian]]
* Creator/ToninoAccolla: Homer Simpson (Seasons 1-23).
* Creator/NanniBaldini: Nelson Muntz (Seasons 4-15).
* Creator/OresteBaldini: Sideshow Mel (since Season 15).
* Creator/GaiaBolognesi: Bart Simpson (since Season 23).
* Creator/LiuBosisio: Marge Simpson (Seasons 1-22), Patty and Selma Bouvier (Seasons 1-21).
* Creator/MinoCaprio: Moe Szyslak (Seasons 1-7) and Abraham "Abe" Simpson (Season 23).
* Creator/MauraCenciarelli: Ralph Wiggum (since Season 10) and Rod Flanders.
* Creator/GilbertaCrispino: Martin Prince (since Season 14) and Todd Flanders.
* Creator/MarcoGuadagno: Nelson Muntz (Seasons 1-2).
* Creator/FrancescaGuadagno: Agnes Skinner (Seasons 22-29).
* Creator/IlariaLatini: Martin Prince in (Seasons 6-12) and Ralph Wiggum (Seasons 6-7).
* Creator/LauraLatini: Ralph Wiggum (Seasons 4-5).
* Creator/DavideLepore: Milhouse Van Houten.
* Creator/AngeloMaggi: Chief Wiggum (since Season 5).
* Creator/FabrizioMazzotta: Krusty the Clown.
* Creator/StellaMusy: Shauna Chalmers.
* Creator/IlariaStagni: Bart Simpson (Seasons 1-22).
* Creator/MonicaWard: Lisa Simpson.
[[/folder]]
[[folder:Japanese]]
'''NOTE:''' The following voice cast is from seasons 1 to 14 only. Starting with season 15, the entire voice cast was replaced with newer voice actors.
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* Creator/ToruOhira: Homer Simpson until his death.
* Creator/TaekoKawata: Maggie Simpson in the TV series. In the theatrical version, Saori Seto voice her instead.
* Creator/NobuoTobita: Milhouse van Houten, Professor Frink, Jimbo Jones, Nick Riviera and Itchy. Creator/YuuSugimoto voiced Milhouse in the home video release of the movie.
* Creator/SayuriYamauchi: Scratchy.
* Creator/HiroyaIshimaru: Lionel Hutz and Duffman.
* Creator/ShigeruChiba: Otto Mann (seasons 1-6), Creator/ShinpachiTsuji (seasons 7-15).
* Creator/DaikiNakamura: Chief Wiggum and Dolph.
* Creator/JunpeiTakiguchi: Abraham "Abe" Simpson and Rabbi Hyman Krustofski until his death.
* Creator/BinShimada: Krusty, Troy [=McClure=], Rainier Wolfcastle (until season 11) and Mr. Sparkle.
* Creator/HiroshiIto: Kent Brockman, Kirk Van Houten, and Fat Tony (movie/theatrical version).
* Creator/MasashiHirose: Barney Gumble, Sideshow Mel and Apu.
* Creator/MinoruInaba: Moe Szyslak and Gil Gunderson.
* Creator/MitsuruOgata: Charles Montgomery Burns (second voice, TV series).
* Creator/VolcanoOta: Seymour Skinner (season 15 onwards)
* Creator/TakumiYamazaki: Arnie Pye.
* Creator/YokuShioya: Artie Ziff (season 1-?), Creator/HideyukiUmezu (?-15).
* Creator/RokuroNaya: Mayor Quimby. Creator/ShinpachiTsuji later replace him in further seasons.
* Creator/YuichiNagashima: Lenny.
* Creator/DaisukeGori: Judge Roy Snyder.
* Creator/KeiTomiyama: [[ShowWithinTheShow Jack]].
* Creator/ShinobuAdachi: Todd Flanders and Martin Prince.
* Creator/YosukeAkimoto: Principal Harlan Dondelinger.
* Creator/ToruFurusawa: Dean Bobby Peterson.
* Creator/JojiNakata: Reverend Lovejoy in the movie (theatrical version).[[note]]Very likely a CastingGag regarding his role as [[SinisterMinister Kirei Kotomine]] in ''VisualNovel/FateStayNight''[[/note]] In the home video version and the proper TV series, he is voiced regularly by Kousuke Meguro instead.
* Creator/MikiIto: Helen Lovejoy in the movie (theatrical version).[[note]]Just like with Nakata, this is very likely a CastingGag regarding her role as Taiga Fujimura in ''VisualNovel/FateStayNight'', through a very hilarious one considering Taiga is technically Kotomine's enemy due to the fact she is the step-sister of Shiro Emiya, his arch-enemy.([[/note]] In the home video version and the proper TV series, she is voiced regularly by Ai Satou instead.
* Creator/KikukoInoue: Collete in "[[Recap/TheSimpsonsS3E10FlamingMoes Flaming Moe's]]".
* Creator/KoichiYamadera: Leon Kompowsky in "[[Recap/TheSimpsonsS3E1StarkRavingDad Stark Raving Dad]]".
* Creator/RyuseiNakao: Mr. Bengstrom in "[[Recap/TheSimpsonsS2E19LisasSubstitute Lisa's Substitute]]".
* Creator/IkueOtani: Tobias in "[[Recap/TheSimpsonsS6E16BartVsAustralia Bart vs. Australia]]".
* Creator/MinamiTakayama: Adil Hoxha in "[[Recap/TheSimpsonsS1E11TheCrepesOfWrath The Crepes of Wrath]]".
* Creator/AkioOtsuka: Ringo Starr in "[[Recap/TheSimpsonsS2E18BrushWithGreatness Brush with Greatness]]".
* Creator/YasunoriMatsumoto: Cowboy Bob in "[[Recap/TheSimpsonsS1E7TheCallOfTheSimpsons The Call of the Simpsons]]".
* Creator/HochuOtsuka: Creator/MelGibson in "[[Recap/TheSimpsonsS11E1BeyondBlunderdome Beyond Blunderdome]]".
* Creator/KeikoToda and Morio Kazama: Dana Scully and Fox Mulder respectively in "[[Recap/TheSimpsonsS8E10TheSpringfieldFiles The Springfield Files]]", both actors reprising their roles from the Japanese dub of their [[Series/TheXFiles home series]].
* Creator/MichieTomizawa: Jessica Lovejoy in "[[Recap/TheSimpsonsS6E7BartsGirlfriend Bart's Girlfriend]]".
* Creator/RihokoYoshida: Mona Simpson in "[[Recap/TheSimpsonsS7E8MotherSimpson Mother Simpson]]".
* Creator/TakeshiAono: Herb Powell in "[[Recap/TheSimpsonsS2E15OhBrotherWhereArtThou Oh Brother, Where Art Thou?]]". Creator/KiyoyukiYanada voiced him in later episodes.
* Creator/AtsukoTanaka: Creator/BrookeShields in "[[Recap/TheSimpsonsS4E19TheFront The Front]]".
* Creator/EmiShinohara: Lurleen Lumpkin in "[[Recap/TheSimpsonsS3E20ColonelHomer Colonel Homer]]''.
* Creator/KumikoWatanabe: Princess Kashmir in "[[Recap/TheSimpsonsS1E10HomersNightOut Homer's Night Out]]".
* Creator/RikaFukami and Creator/KenyuuHoriuchi: Creator/KimBasinger and Creator/AlecBaldwin in "[[Recap/TheSimpsonsS10E5WhenYouDishUponAStar When You Dish Upon a Star]]".
* Creator/KenNarita: Jesse Grass in "[[Recap/TheSimpsonsS12E4LisaTheTreeHugger Lisa the Tree Hugger]]".
* Creator/YukoKobayashi: Mindy Simmons in "[[Recap/TheSimpsonsS5E9TheLastTemptationOfHomer The Last Temptation of Homer]]".
* Creator/MitsuruMiyamoto: Hugh Parkfield in "[[Recap/TheSimpsonsS6E19LisasWedding Lisa's Wedding]]".
* Creator/ReiIgarashi: Sara Sloane in "[[Recap/TheSimpsonsS14E13AStarIsBornAgain A Star is Born Again]]".
* Creator/KozoShioya: Larry Burns in "[[Recap/TheSimpsonsS8E4BurnsBabyBurns Burns, Baby Burns]]".
* Creator/NaokoMatsui: Samantha Stanky in "[[Recap/TheSimpsonsS3E23BartsFriendFallsInLove Bart's Friend Falls in Love]]".
* Creator/NaoyaUchida: Brother Faith in "[[Recap/TheSimpsonsS11E11FaithOff Faith Off]]".
* Creator/TesshoGenda: President Creator/ArnoldSchwarzenegger in the movie (both video and theatrical releases), this one a CastingGag around the fact he is the regular dub voice of him.
* Creator/TomomichiNishimura: Russ Cargill in the movie (theatrical release), while Creator/UnshoIshizuka voiced him in the home video version instead.
* Creator/UraraTakano: Mrs. Muntz in the movie (theatrical release)
* Creator/DaisukeHirakawa: Loki in ''WesternAnimation/TheGoodTheBartAndTheLoki'' (RoleReprise from the ''Franchise/MarvelCinematicUniverse'').
[[/folder]]
[[folder:European Spanish]]
* Creator/IsachaMengibar: Lisa Simpson.
* Creator/CheloMolina: Milhouse Van Houten.
* Creator/CheloVivares: Ralph Wiggum, Martin Prince, Itchy, Todd Flanders.
[[/folder]]
[[folder:Latin American Spanish]]
* Creator/PatriciaAcevedo: Lisa and Maggie Simpson until Season 15, and from season 31 onwards.
* Creator/RossyAguirre: Dolph in the first season, Allison Taylor in the sixth and Ms. Hoover in the tenth.
* Creator/YamilAtala: Cowboy Bob in "[[Recap/TheSimpsonsS1E7TheCallOfTheSimpsons The Call of the Simpsons]]".
* Creator/SalvadorDelgado: Lionel Hutz, Cecil Terwilliger, Troy [=McLure=] in season 7 and Mike Scoscia in "[[Recap/TheSimpsonsS3E17HomerAtTheBat Homer at the Bat]]".
* Creator/RocioGarcel: Lurleen Lumpkin in "[[Recap/TheSimpsonsS3E20ColonelHomer Colonel Homer]]".
* Creator/BlasGarcia: Arnold Schwarzenegger in ''WesternAnimation/TheSimpsonsMovie''.
* Creator/ReneGarcia: Artie Ziff in seasons 13 and 15, [[Music/{{Aerosmith}} Joe Perry]] in "[[Recap/TheSimpsonsS3E10FlamingMoes Flaming Moe's]]", Music/{{Sting}}, and Bill in seasons 3 and 10
* Creator/CristinaHernandez: Allison Taylor in the tenth season.
* Creator/CarlosInigo: Professor Frink from seasons 3 to 15 and Toshiro.
* Creator/JoseLavat: {{God}} in the tenth season.
* Creator/AraceliDeLeon: Rod Flanders in seasons 3,5 and 6. Creator/LilianaBarba voiced him from seasons 9 to 12.
* Creator/HermanLopez: Otto Mann from seasons 1 to 15.
* Creator/EdsonMatus: Nelson Muntz from seasons 16 to 17, Akira, Duffman, and Rainer Wolfcastle from season 25 onwards. Creator/EduardoGarza voiced him in season 8.
* Creator/RicardoMendoza: [[TheDanza Mendoza]] in "[[Recap/TheSimpsonsS2E15OhBrotherWhereArtThou Oh Brother, Where Art Thou?]]".
* Creator/ArturoMercado: Tom Hanks in ''WesternAnimation/TheSimpsonsMovie''
* Creator/AlfonsoObregonInclan: Cletus in seasons 11 and 12, [[Music/{{Aerosmith}} Joey Kramer]] in "[[Recap/TheSimpsonsS3E10FlamingMoes Flaming Moe's]]" and Creator/BobHope.
* Creator/GloriaObregon: Selma Bouvier.
* Creator/JoseLuisOrozco: Sideshow Bob in season 3, Leon Kompowsky, and Kent Brockman from season 32 onwards.
* Creator/MarianaOrtiz: Manjula since season 18 onwards.
* Creator/GabrielPingarron: Seymour Skinner from seasons 9 to 15.
* Creator/GerardoReyero: Reverend Lovejoy in seasons 7, 10 to 15, Jose Canseco in "[[Recap/TheSimpsonsS3E17HomerAtTheBat Homer at the Bat]]", and also Rainer Wolfcastle in season 7.
* Creator/BenjaminRivera: Jimbo Jones from seasons 2 to 14. Creator/CarlosInigo voiced Dolph from seasons 10 to 13.
* Creator/NallelySolis: Lisa Simpson, Milhouse Van Houten (since Season 16).
* Creator/MartinSoto: Mayor Joe Quimby from seasons 10 to 15.
* Creator/LauraTorres: Martin Prince, Kearney in the first season, Chuck, Scratchy in some episodes and Ralph Wiggum until Season 13. Creator/MarianaOrtiz, her later mother Creator/AraceliDeLeon and Creator/IsabelMartinon voiced Martin for some episodes.
* Creator/XochitlUgarte: Kumiko Albertson.
* Creator/GerardoVasquez: Doctor Hibbert in from season 10 to season 14, and from season 16 onwards. He was also Seymour Skinner and Barney Gumble from seasons 16 to 31.
* Creator/HumbertoVelez: Homer Simpson, [[Series/MarriedWithChildren Al Bundy]] in his brief cameo in "[[Recap/TheSimpsonsS4E20WhackingDay Whacking Day]]", and Creator/MattGroening until Season 15, then from season 31 onwards.
[[/folder]]
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